benserazide has been researched along with homovanillic acid in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (51.22) | 18.7374 |
| 1990's | 11 (26.83) | 18.2507 |
| 2000's | 5 (12.20) | 29.6817 |
| 2010's | 4 (9.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lorenzo, AV; Snodgrass, SR; Uretsky, NJ | 1 |
| Maitre, L; Waldmeier, PC | 1 |
| Marttila, R; Rinne, UK | 1 |
| Rinne, UK; Siirtola, T; Sonninen, V | 2 |
| Algeri, S; Campanella, G; Cerletti, C; Dolfini, E; Jori, A; Rinaldi, F | 1 |
| Geissbühler, F; Widmer, J | 1 |
| Groppe, G; Kuschinsky, K | 1 |
| Kuschinsky, K | 1 |
| Hyyppä, MT; Jolma, T; Riekkinen, P; Rinne, UK | 1 |
| Constantinidis, J; Gaillard, JM; Tissot, R | 1 |
| Cramer, H; Kuntzmann, F; Masson, H; Popescu, I; Strubel, D | 1 |
| Dissing, IC; Gerdes, AM; Güttler, F; Lou, H; Lykkelund, C; Pakkenberg, H; Rasmussen, V | 1 |
| Kraus, P; Kuhn, W; Przuntek, H | 1 |
| Liu, DK | 2 |
| Cohen, Y; el Gemayel, G; Jacquot, C; Prioux-Guyonneau, M; Trouvin, JH | 1 |
| Aizenstein, ML; de-Lucia, R; Scavone, C; Steinschreiber, S | 1 |
| Eplov, L; Nielsen, M; Scheel-Krüger, J | 1 |
| Edwards, DJ; Sedlock, ML | 1 |
| Jackson, DM; Miller, LP; Walters, JR | 1 |
| Watanabe, Y | 1 |
| Chen, CF; Hsieh, CC; Hsieh, MT; Peng, WH; Su, SH; Tsai, HY | 1 |
| Da Prada, M; Napolitano, A; Zürcher, G | 1 |
| De Klippel, N; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Antonin, KH; Bieck, PR; Dostert, P; Farger, G; Nilsson, EB; Schmidt, EK; Strolin Benedetti, M; Waldmeier, PC | 1 |
| Da Prada, M; Dingemanse, J; Zürcher, G | 1 |
| Chen, CF; Ho, YF; Hsieh, MT; Peng, WH; Wu, CR | 1 |
| Ichikawa, M; Matsuyama, K; Nakashima, M; Nakashima, MN; Sakurai, M; Sasaki, H; Zhao, MF | 1 |
| Achilli, G; Banting, A; Banting, S; Le Bars, D; Weil-Fugazza, J | 1 |
| Myers, CS; Wagner, GC; Witten, M; Yu, YL | 1 |
| Halladay, AK; Myers, CS; Wagner, GC; Widmer, DA | 1 |
| Gu, SD; Sun, XF; Wang, W; Zhao, DZ | 1 |
| Dziubina, A; Gołembiowska, K | 1 |
| Cooper, JD; Davies, MI; Heppert, KE; Lunte, SM | 1 |
| Buck, K; Ferger, B | 1 |
| Dziubina, A; Gołembiowska, K; Kamińska, K; Kowalska, M | 1 |
| Fukumura, T; Hosoi, R; Inoue, O; Nakao, R; Okada, M; Suzuki, K; Zhang, MR | 1 |
| Chao, OY; Huston, JP; Mattern, C; Nikolaus, S; Pum, ME; Ruocco, LA; Silva, AM; Wessler, J | 1 |
| Deng, M; Fang, Y; Huang, L; Li, L; Zhang, S | 1 |
| Di Paolo, T; Grégoire, L; Morin, N; Morissette, M | 1 |
2 trial(s) available for benserazide and homovanillic acid
| Article | Year |
|---|---|
Effects of L-tryptophan treatment on central indoleamine metabolism and short-lasting neurologic disturbances in multiple sclerosis.
Topics: Adult; Benserazide; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Multiple Sclerosis; Tryptophan | 1975 |
Tetrahydrobiopterin and Parkinson's disease.
Topics: Adult; Antiparkinson Agents; Benserazide; Biopterins; Clinical Trials as Topic; Drug Combinations; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Tyrosine | 1989 |
39 other study(ies) available for benserazide and homovanillic acid
| Article | Year |
|---|---|
Studies on the mechanism of depletion of striatal dopamine by alpha-methyl-m-tyrosine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brocresine; Corpus Striatum; Dopamine; Homovanillic Acid; In Vitro Techniques; Male; Methyltyrosines; p-Hydroxyamphetamine; Rats; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 1975 |
Effects of baclofen on dopamine metabolism and interaction with neuroleptic effects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aminobutyrates; Animals; Antipsychotic Agents; Baclofen; Benserazide; Carboxy-Lyases; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Female; Homovanillic Acid; Limbic System; Male; Methyltyrosines; Picrotoxin; Rats; Scopolamine | 1978 |
Brain dopamine receptor stimulation and the relief of Parkinsonism: relationship between bromocriptine and levodopa.
Topics: Benserazide; Brain; Bromocriptine; Female; Homovanillic Acid; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine | 1978 |
L-deprenyl treatment of on-off phenomena in Parkinson's disease.
Topics: Aged; Benserazide; Dopamine; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Phenethylamines; Selegiline; Vanilmandelic Acid | 1978 |
Correlation of clinical symptoms, HVA and 5-HIAA in csf and plasma L-DOPA in Parkinsonian patients treated with L-DOPA and L-DOPA + RO 4-4602.
Topics: Benserazide; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Time Factors | 1977 |
[Urinary excretion of 3,4-dihydroxyphenyl-alanine, 3-O-methyldopa, dopamine and homovanillic acid in man. Effects of an inhibitor of decarboxylase of aromatic amino acids (Benserazide) (author's transl)].
Topics: Adult; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Methyldopa; Phenylacetates; Time Factors | 1976 |
Stimulation and inhibition of serotoninergic mechanisms in rat brain: alterations of morphine effects on striatal dopamine metabolism and on motility.
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Male; Methamphetamine; Morphine; Motor Activity; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1975 |
Does chronic morphine treatment induce a supersensitivity of dopamine receptors in rat brain?
Topics: Animals; Apomorphine; Benserazide; Brain; Corpus Striatum; Dopamine; Homovanillic Acid; Humans; Levodopa; Male; Morphine; Probenecid; Rats; Receptors, Drug; Stereotyped Behavior; Substance Withdrawal Syndrome | 1975 |
Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Benserazide; Biogenic Amines; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Metanephrine; Middle Aged; Normetanephrine; Parkinson Disease; Tyramine; Vanilmandelic Acid | 1975 |
Effect of peripheral decarboxylase inhibition on HVA and 5HIAA in cerebrospinal fluid of depressed patients.
Topics: Adult; Aged; Benserazide; Depression; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylacetates | 1975 |
Somatostatin-like immunoreactivity in the cerebrospinal fluid of aged patients with Parkinson's disease. The effect of dopatherapy.
Topics: Aged; Aged, 80 and over; Benserazide; Bromocriptine; Cognition Disorders; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Male; Parkinson Disease; Severity of Illness Index; Somatostatin | 1990 |
The effect of R-(-)-deprenyl in de novo parkinsonian patients pretreated with levodopa and decarboxylase inhibitor correlated to depression and MHPG, HIAA and HVA levels in the cerebrospinal fluid.
Topics: Benserazide; Depression; Double-Blind Method; Drug Therapy, Combination; Female; Glycols; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Middle Aged; Motor Activity; Parkinson Disease; Phenethylamines; Selegiline | 1989 |
[The concentration of homovanillic acid and leucine-enkephalin in the lumbar CSF of patients with Parkinson's disease before and after madopar treatment].
Topics: Adult; Aged; Benserazide; Carboxy-Lyases; Drug Combinations; Enkephalin, Leucine; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1989 |
Re-evaluation of the L-dopa loading effect on dopamine metabolism in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
Differential changes in dopaminergic receptor sensitivity induced by agonist drugs.
Topics: Animals; Apomorphine; Benserazide; Brain Chemistry; Catalepsy; Drug Therapy, Combination; Haloperidol; Homovanillic Acid; Levodopa; Male; Mice; Mice, Inbred Strains; Receptors, Dopamine | 1985 |
Protriptyline induced inhibition of the in vivo 3H-noradrenaline synthesis from 3H-L-dopa in the rat brain.
Topics: Animals; Antidepressive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Brain Chemistry; Catecholamines; Cerebral Ventricles; Chromatography, Ion Exchange; Dibenzocycloheptenes; Homovanillic Acid; Injections; Levodopa; Male; Norepinephrine; Propylamines; Rats; Specific Pathogen-Free Organisms; Spectrometry, Fluorescence; Time Factors; Tritium; Tyrosine | 1974 |
Increased brain concentration of homovanillic acid in rats treated with threo-3,4-dihydroxyphenylserine.
Topics: Animals; Benserazide; Brain Chemistry; Droxidopa; Homovanillic Acid; Male; Norepinephrine; Phenylacetates; Rats; Rats, Inbred Strains; Serine | 1982 |
Chronic L-DOPA-pretreatment of rats: an electrophysiological and biochemical study in the basal ganglia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Basal Ganglia; Benserazide; Corpus Striatum; Dextroamphetamine; Dopamine; Evoked Potentials; Homovanillic Acid; Levodopa; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1982 |
[Interactions of cerebral serotonin and catecholamines].
Topics: 5,7-Dihydroxytryptamine; Animals; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Catecholamines; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Nerve Endings; Neurons; Norepinephrine; Rats; Serotonin; Tryptophan | 1983 |
[Madopar in the treatment of paralysis agitans: II. TRH activation test, EMG examination and HVA level in cerebrospinal fluid before and after treatment].
Topics: Aged; Benserazide; Drug Combinations; Electromyography; Female; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylacetates; Thyrotropin; Thyrotropin-Releasing Hormone | 1980 |
Effects of palmatine on motor activity and the concentration of central monoamines and its metabolites in rats.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Benserazide; Berberine Alkaloids; Brain; Brain Stem; Cerebral Cortex; Dopamine; Drug Interactions; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Methyltyrosines; Motor Activity; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin | 1993 |
Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Homovanillic Acid; Levodopa; Male; Methylation; Microdialysis; Neostriatum; Nitrophenols; Rats; Tolcapone | 1995 |
Biotransformation of locally applied L-dopa in the corpus striatum of the hemi-parkinsonian rat studied with microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Biotransformation; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Nomifensine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Tetrodotoxin | 1994 |
Clinical pharmacology of the new COMT inhibitor CGP 28,014.
Topics: Amidines; Animals; Benserazide; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Homovanillic Acid; Humans; Isoquinolines; Kinetics; Methoxyhydroxyphenylglycol; Norepinephrine; Pyridones; Rats; Tyrosine; Vanilmandelic Acid | 1993 |
Potent COMT inhibition by Ro 40-7592 in the periphery and in the brain. Preclinical and clinical findings.
Topics: Animals; Benserazide; Benzophenones; Brain; Carbidopa; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Dose-Response Relationship, Drug; Erythrocytes; Homovanillic Acid; Humans; Levodopa; Male; Nitrophenols; Peripheral Nerves; Rats; S-Adenosylhomocysteine; S-Adenosylmethionine; Tolcapone | 1993 |
Effects of Hemerocallis flava on motor activity and the concentration of central monoamines and its metabolites in rats.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Amines; Analysis of Variance; Animals; Benserazide; Brain Stem; Cerebral Cortex; Dopamine; Dopamine Agents; Enzyme Inhibitors; Fenclonine; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Mandelic Acids; Methyltyrosines; Motor Activity; Norepinephrine; Plant Extracts; Plants, Medicinal; Rats; Serotonin; Serotonin Agents | 1996 |
In vivo microdialysis to determine the relative pharmacokinetics of drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benserazide; Brain Chemistry; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Interactions; Electrochemistry; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Microdialysis; Neostriatum; Rats; Rats, Wistar | 1996 |
Tyrosine and tryptophan derivatives in pig lumbar cerebrospinal fluid. Effects of subchronic administration of dopa associated with benserazide.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Benserazide; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Swine; Tryptamines; Tryptophan; Tyrosine | 1996 |
L-DOPA exacerbates amphetamine-induced dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Synergism; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Mice; Organ Specificity; Serotonin | 1998 |
Neurotoxic effects of amphetamine plus L-DOPA.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Interactions; Frontal Lobe; Homovanillic Acid; Hypothalamus; Levodopa; Male; Mice; Neurons; Neurotoxins; Organ Specificity; Serotonin; Time Factors | 1999 |
[The effect of shourong compound formula on levels of dopamine and its metabolites in brain of Parkinson's disease mice induced by reserpine].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Dopamine; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Homovanillic Acid; Levodopa; Male; Mice; Parkinson Disease, Secondary; Plant Extracts; Plants, Medicinal; Reserpine | 2002 |
Effect of the adenosine A2A receptor antagonist 8-(3-chlorostyryl)caffeine on L-DOPA biotransformation in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Benserazide; Brain Chemistry; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Reserpine | 2004 |
Evaluation of an osmotic pump for microdialysis sampling in an awake and untethered rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain Chemistry; Dopamine; Extracellular Fluid; Homovanillic Acid; Hydroxyindoleacetic Acid; Infusion Pumps; Levodopa; Male; Microdialysis; Neurochemistry; Neurotransmitter Agents; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Serotonin; Up-Regulation; Wakefulness | 2007 |
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: a bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Benserazide; Brain Injuries; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar | 2008 |
Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Area Under Curve; Benserazide; Catalepsy; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Time Factors; Triazines; Triazoles; Xanthines | 2009 |
Microdialysis with radiometric monitoring of L-[β-11C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Enzyme Inhibitors; Extracellular Fluid; Homovanillic Acid; Levodopa; Male; Microdialysis; Monoamine Oxidase Inhibitors; Neostriatum; Pargyline; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2011 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electrochemistry; Exploratory Behavior; Forelimb; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2012 |
Coadministration of β-asarone and levodopa increases dopamine in rat brain by accelerating transformation of levodopa: a different mechanism from Madopar.
Topics: 3,4-Dihydroxyphenylacetic Acid; Allylbenzene Derivatives; Animals; Anisoles; Benserazide; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Drug Combinations; Drug Interactions; Homovanillic Acid; Levodopa; Male; Monoamine Oxidase; Rats; Serotonin; Tyrosine 3-Monooxygenase | 2014 |
Effect of a chronic treatment with an mGlu5 receptor antagonist on brain serotonin markers in parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Levodopa; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Protein Binding; Pyridines; Serotonin | 2015 |