benserazide has been researched along with 3,4-dihydroxyphenylacetic acid in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (31.25) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 5 (15.63) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lorenzo, AV; Snodgrass, SR; Uretsky, NJ | 1 |
| Maitre, L; Waldmeier, PC | 1 |
| Eplov, L; Nielsen, M; Scheel-Krüger, J | 1 |
| Rinne, UK; Siirtola, T; Sonninen, V | 1 |
| Bondarenko, NA; Kudrin, VS; Miroshnichenko, II; Rayevsky, KS | 1 |
| Cohen, Y; el Gemayel, G; Jacquot, C; Prioux-Guyonneau, M; Trouvin, JH | 1 |
| Bondarenko, NA; Kudrin, VS; Miroshnichenko, II | 1 |
| Jackson, DM; Miller, LP; Walters, JR | 1 |
| Baker, H; Joh, TH; Kawano, T; Margolis, FL | 1 |
| Baraczka, K; Fekete, MI; Kanyicska, B | 1 |
| Gulliver, PA; Hagan, RM; Raxworthy, MJ | 1 |
| Da Prada, M; Napolitano, A; Zürcher, G | 1 |
| Pestana, M; Soares-da-Silva, P | 1 |
| De Klippel, N; Ebinger, G; Herregodts, P; Michotte, Y; Sarre, S | 1 |
| Christensen, NJ; Eldrup, E; Hetland, ML | 1 |
| Lambás-Señas, L; Ortemann, C; Pujol, JF; Renaud, B; Robert, F | 1 |
| Christensen, NJ; Eldrup, E; Jensen, EW; Kelbaek, H; Nielsen, SL | 1 |
| Ichikawa, M; Matsuyama, K; Nakashima, M; Nakashima, MN; Sakurai, M; Sasaki, H; Zhao, MF | 1 |
| Achilli, G; Banting, A; Banting, S; Le Bars, D; Weil-Fugazza, J | 1 |
| Crevoisier, C; Dingemanse, J; Kleinbloesem, CH; Wood, ND; Zürcher, G | 1 |
| Myers, CS; Wagner, GC; Witten, M; Yu, YL | 1 |
| Halladay, AK; Myers, CS; Wagner, GC; Widmer, DA | 1 |
| Gu, SD; Sun, XF; Wang, W; Zhao, DZ | 1 |
| Dziubina, A; Gołembiowska, K | 2 |
| Cooper, JD; Davies, MI; Heppert, KE; Lunte, SM | 1 |
| Buck, K; Ferger, B | 1 |
| Dziubina, A; Gołembiowska, K; Kamińska, K; Kowalska, M | 1 |
| Fukumura, T; Hosoi, R; Inoue, O; Nakao, R; Okada, M; Suzuki, K; Zhang, MR | 1 |
| Chao, OY; Huston, JP; Mattern, C; Nikolaus, S; Pum, ME; Ruocco, LA; Silva, AM; Wessler, J | 1 |
| Deng, M; Fang, Y; Huang, L; Li, L; Zhang, S | 1 |
| Di Paolo, T; Grégoire, L; Morin, N; Morissette, M | 1 |
2 trial(s) available for benserazide and 3,4-dihydroxyphenylacetic acid
| Article | Year |
|---|---|
Increase in plasma 3,4-dihydroxyphenylalanine (DOPA) appearance rate after inhibition of DOPA decarboxylase in humans.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Dihydroxyphenylalanine; Dopamine; Humans; Male; Metabolic Clearance Rate | 1994 |
Pharmacodynamics of benserazide assessed by its effects on endogenous and exogenous levodopa pharmacokinetics.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Antiparkinson Agents; Benserazide; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; Levodopa; Male; Middle Aged; Tyrosine | 1997 |
30 other study(ies) available for benserazide and 3,4-dihydroxyphenylacetic acid
| Article | Year |
|---|---|
Studies on the mechanism of depletion of striatal dopamine by alpha-methyl-m-tyrosine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brocresine; Corpus Striatum; Dopamine; Homovanillic Acid; In Vitro Techniques; Male; Methyltyrosines; p-Hydroxyamphetamine; Rats; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 1975 |
Effects of baclofen on dopamine metabolism and interaction with neuroleptic effects.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aminobutyrates; Animals; Antipsychotic Agents; Baclofen; Benserazide; Carboxy-Lyases; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Drug Interactions; Female; Homovanillic Acid; Limbic System; Male; Methyltyrosines; Picrotoxin; Rats; Scopolamine | 1978 |
The effect of amitriptyline, desipramine and imipramine on the vivo brain synthesis of 3H-noradrenaline from 3H-L-dopa in the rat.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Benserazide; Brain; Chromatography, Thin Layer; Desipramine; Dopamine; Imipramine; Levodopa; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Normetanephrine; Rats; Tryptamines | 1975 |
Urinary excretion of monoamines and their metabolites in patients with Parkinson's disease. Response to long-term treatment with levodopa alone or in combination with a dopa decarboxylase inhibitor and clinical correlations.
Topics: 3,4-Dihydroxyphenylacetic Acid; Benserazide; Biogenic Amines; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Male; Metanephrine; Middle Aged; Normetanephrine; Parkinson Disease; Tyramine; Vanilmandelic Acid | 1975 |
Cognitive deficiency induced by the acute stress in rats: a possible role of brain catecholaminergic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain Chemistry; Cognition Disorders; Dihydroxyphenylalanine; Escape Reaction; Exploratory Behavior; Levodopa; Male; Norepinephrine; Rats; Stress, Physiological | 1990 |
Re-evaluation of the L-dopa loading effect on dopamine metabolism in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Drug Therapy, Combination; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
[Effect of L-dihydroxyphenylalanine on rat behavior and on catecholamine metabolism of the brain in rats with different degrees of emotional-behavioral reactivity].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Benserazide; Brain; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Drug Combinations; Drug Interactions; Emotions; Levodopa; Male; Rats | 1988 |
Chronic L-DOPA-pretreatment of rats: an electrophysiological and biochemical study in the basal ganglia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Basal Ganglia; Benserazide; Corpus Striatum; Dextroamphetamine; Dopamine; Evoked Potentials; Homovanillic Acid; Levodopa; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Synaptic Transmission; Tyrosine 3-Monooxygenase | 1982 |
Transneuronal regulation of tyrosine hydroxylase expression in olfactory bulb of mouse and rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Benserazide; Dihydroxyphenylalanine; Dopamine; Female; Levodopa; Mice; Mice, Inbred Strains; Neurons; Norepinephrine; Olfactory Bulb; Rats; Rats, Inbred Strains; Reserpine; Species Specificity; Tyrosine 3-Monooxygenase | 1983 |
Changes in dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in human cerebrospinal fluid after L-dopa and deprenyl administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Benserazide; Dopamine; Humans; Levodopa; Monoamine Oxidase; Phenethylamines; Phenylacetates; Selegiline | 1983 |
Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzyl Compounds; Carbidopa; Catechol O-Methyltransferase; Hydrazines; Kinetics; Liver; Parkinson Disease; S-Adenosylmethionine; Substrate Specificity; Swine | 1980 |
Effects of tolcapone, a novel catechol-O-methyltransferase inhibitor, on striatal metabolism of L-dopa and dopamine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzophenones; Catechol O-Methyltransferase Inhibitors; Chromatography, High Pressure Liquid; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Homovanillic Acid; Levodopa; Male; Methylation; Microdialysis; Neostriatum; Nitrophenols; Rats; Tolcapone | 1995 |
Effect of type A and B monoamine oxidase selective inhibition by Ro 41-1049 and Ro 19-6327 on dopamine outflow in rat kidney slices.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Dopamine; In Vitro Techniques; Isoenzymes; Kidney Cortex; Levodopa; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Picolinic Acids; Rats; Rats, Wistar; Thiazoles | 1994 |
Biotransformation of locally applied L-dopa in the corpus striatum of the hemi-parkinsonian rat studied with microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Biotransformation; Corpus Striatum; Denervation; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Homovanillic Acid; Levodopa; Male; Microdialysis; Nomifensine; Oxidopamine; Parkinson Disease, Secondary; Rats; Rats, Wistar; Tetrodotoxin | 1994 |
Microdialysis monitoring of 3,4-dihydroxyphenylalanine accumulation after decarboxylase inhibition: a means to estimate in vivo changes in tyrosine hydroxylase activity of the rat locus ceruleus.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Chromatography, High Pressure Liquid; Dialysis; Dihydroxyphenylalanine; Hydrazines; Kinetics; Locus Coeruleus; Male; Methyltyrosines; Microchemistry; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase | 1993 |
Venous plasma noradrenaline increases with age: correlation to total blood volume and long-term smoking habits.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Aged, 80 and over; Aging; Benserazide; Blood Volume; Body Weight; Cardiac Output; Dihydroxyphenylalanine; Epinephrine; Humans; Male; Middle Aged; Norepinephrine; Smoking; Sympathetic Nervous System | 1993 |
In vivo microdialysis to determine the relative pharmacokinetics of drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Benserazide; Brain Chemistry; Carbidopa; Chromatography, High Pressure Liquid; Dopamine; Drug Interactions; Electrochemistry; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Microdialysis; Neostriatum; Rats; Rats, Wistar | 1996 |
Tyrosine and tryptophan derivatives in pig lumbar cerebrospinal fluid. Effects of subchronic administration of dopa associated with benserazide.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Benserazide; Drug Interactions; Female; Homovanillic Acid; Hydroxyindoleacetic Acid; Kynurenine; Levodopa; Male; Methoxyhydroxyphenylglycol; Normetanephrine; Swine; Tryptamines; Tryptophan; Tyrosine | 1996 |
L-DOPA exacerbates amphetamine-induced dopamine depletion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Synergism; Frontal Lobe; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Mice; Organ Specificity; Serotonin | 1998 |
Neurotoxic effects of amphetamine plus L-DOPA.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Corpus Striatum; Dextroamphetamine; Dopamine; Drug Interactions; Frontal Lobe; Homovanillic Acid; Hypothalamus; Levodopa; Male; Mice; Neurons; Neurotoxins; Organ Specificity; Serotonin; Time Factors | 1999 |
[The effect of shourong compound formula on levels of dopamine and its metabolites in brain of Parkinson's disease mice induced by reserpine].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Dopamine; Drug Combinations; Drug Synergism; Drugs, Chinese Herbal; Homovanillic Acid; Levodopa; Male; Mice; Parkinson Disease, Secondary; Plant Extracts; Plants, Medicinal; Reserpine | 2002 |
Effect of the adenosine A2A receptor antagonist 8-(3-chlorostyryl)caffeine on L-DOPA biotransformation in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Adrenergic Uptake Inhibitors; Animals; Benserazide; Brain Chemistry; Caffeine; Corpus Striatum; Dopamine; Dopamine Agents; Homovanillic Acid; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Reserpine | 2004 |
Evaluation of an osmotic pump for microdialysis sampling in an awake and untethered rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain Chemistry; Dopamine; Extracellular Fluid; Homovanillic Acid; Hydroxyindoleacetic Acid; Infusion Pumps; Levodopa; Male; Microdialysis; Neurochemistry; Neurotransmitter Agents; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Serotonin; Up-Regulation; Wakefulness | 2007 |
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: a bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic-L-Amino-Acid Decarboxylases; Behavior, Animal; Benserazide; Brain Injuries; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Drug Interactions; Dyskinesia, Drug-Induced; Enzyme Inhibitors; Homovanillic Acid; Levodopa; Male; Microdialysis; Oxidopamine; Rats; Rats, Wistar | 2008 |
Effect of adenosine A(2A) receptor antagonists on L-DOPA-induced hydroxyl radical formation in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Area Under Curve; Benserazide; Catalepsy; Corpus Striatum; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Homovanillic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Rats; Rats, Wistar; Time Factors; Triazines; Triazoles; Xanthines | 2009 |
Microdialysis with radiometric monitoring of L-[β-11C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Catechol O-Methyltransferase Inhibitors; Catechols; Chromatography, High Pressure Liquid; Dopamine; Dopamine Agents; Enzyme Inhibitors; Extracellular Fluid; Homovanillic Acid; Levodopa; Male; Microdialysis; Monoamine Oxidase Inhibitors; Neostriatum; Pargyline; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2011 |
Effect of adenosine A(2A) receptor antagonists and L-DOPA on hydroxyl radical, glutamate and dopamine in the striatum of 6-OHDA-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenosine A2 Receptor Antagonists; Animals; Benserazide; Caffeine; Dopamine; Glutamic Acid; Hydroxyl Radical; Levodopa; Male; Microdialysis; Neostriatum; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles | 2012 |
Intranasally applied L-DOPA alleviates parkinsonian symptoms in rats with unilateral nigro-striatal 6-OHDA lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Benserazide; Chromatography, High Pressure Liquid; Corpus Striatum; Disease Models, Animal; Dopamine; Electrochemistry; Exploratory Behavior; Forelimb; Functional Laterality; Homovanillic Acid; Hydroxyindoleacetic Acid; Levodopa; Male; Motor Activity; Motor Skills; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Wistar; Substantia Nigra; Sympatholytics | 2012 |
Coadministration of β-asarone and levodopa increases dopamine in rat brain by accelerating transformation of levodopa: a different mechanism from Madopar.
Topics: 3,4-Dihydroxyphenylacetic Acid; Allylbenzene Derivatives; Animals; Anisoles; Benserazide; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Drug Combinations; Drug Interactions; Homovanillic Acid; Levodopa; Male; Monoamine Oxidase; Rats; Serotonin; Tyrosine 3-Monooxygenase | 2014 |
Effect of a chronic treatment with an mGlu5 receptor antagonist on brain serotonin markers in parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Brain; Disease Models, Animal; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Female; Homovanillic Acid; Levodopa; Macaca fascicularis; Ovariectomy; Parkinsonian Disorders; Protein Binding; Pyridines; Serotonin | 2015 |