benproperine has been researched along with piperidines in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (66.67) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, XY; Du, ZM; Kang, Y; Zhong, DF | 1 |
| Chen, XY; Du, ZM; Huang, HH; Zhong, DF | 1 |
| Chen, S; Kong, W; Li, W; Li, Y; Min, L; Zhong, D | 1 |
| Dong, Y; Li, Y; Sun, Y; Zhang, Y; Zhong, D | 1 |
| Chen, SW; Li, Y; Maeba, I; Zhong, DF | 1 |
| Liu, MY; Meng, Y; Ren, YL; Zhang, HQ | 1 |
| Li, H; Liu, D; Wu, D; Zhang, Y; Zhang, Z | 1 |
| Chi, SW; Choi, J; Han, DC; Han, YM; Kang, JS; Kwon, BM; Lee, CW; Lee, S; Lee, SK; Lee, YJ; Moon, JH; Yoon, YJ; Yun, J | 1 |
| Huang, Y; Li, Q; Liu, J; Lu, Y; Ma, L; Qin, S; Weng, N; Yang, M; Zhang, H; Zhang, X; Zhang, Z; Zheng, S; Zhou, L | 1 |
1 trial(s) available for benproperine and piperidines
| Article | Year |
|---|---|
[Enantioselective pharmacokinetics of benproperine in healthy volunteers].
Topics: Administration, Oral; Adult; Antitussive Agents; Area Under Curve; Benzhydryl Compounds; Humans; Male; Piperidines; Stereoisomerism | 2000 |
8 other study(ies) available for benproperine and piperidines
| Article | Year |
|---|---|
[Study on hydroxylated metabolites of benproperine in human urine].
Topics: Adult; Antitussive Agents; Benzhydryl Compounds; Chromatography, High Pressure Liquid; Humans; Hydroxylation; Male; Molecular Structure; Piperidines; Spectrometry, Mass, Electrospray Ionization | 2000 |
Anti-tussive activity of benproperine enantiomers on citric-acid-induced cough in conscious guinea-pigs.
Topics: Animals; Antitussive Agents; Benzhydryl Compounds; Citric Acid; Cough; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Male; Piperidines; Stereoisomerism; Time Factors | 2004 |
Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry.
Topics: Antitussive Agents; Benzhydryl Compounds; Calibration; Chromatography, Liquid; Humans; Piperidines; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2006 |
Identification of some benproperine metabolites in humans and investigation of their antitussive effect.
Topics: Adult; Animals; Antitussive Agents; Benzhydryl Compounds; Chromatography, Liquid; Citric Acid; Cough; Female; Guinea Pigs; Humans; Male; Piperidines; Spectrometry, Mass, Electrospray Ionization | 2005 |
[Nondestructive quantitative analysis of Cofrel medicines by improved partial least squares-NIR spectroscopy].
Topics: Algorithms; Antitussive Agents; Benzhydryl Compounds; Chromatography, High Pressure Liquid; Least-Squares Analysis; Piperidines; Principal Component Analysis; Reproducibility of Results; Spectroscopy, Near-Infrared; Technology, Pharmaceutical | 2007 |
Unravelling the binding mechanism of benproperine with human serum albumin: A docking, fluorometric, and thermodynamic approach.
Topics: Benzhydryl Compounds; Binding Sites; Calorimetry; Fluorescence; Fluorometry; Humans; Molecular Docking Simulation; Piperidines; Serum Albumin; Thermodynamics | 2018 |
Benproperine, an ARPC2 inhibitor, suppresses cancer cell migration and tumor metastasis.
Topics: Actin-Related Protein 2-3 Complex; Animals; Antineoplastic Agents; Benzhydryl Compounds; Cell Movement; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Piperidines; Protein Structure, Secondary; Protein Structure, Tertiary; Xenograft Model Antitumor Assays | 2019 |
Repurposing antitussive benproperine phosphate against pancreatic cancer depends on autophagy arrest.
Topics: Animals; Antitussive Agents; Autophagy; Benzhydryl Compounds; Cell Line, Tumor; Drug Repositioning; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Piperidines; Xenograft Model Antitumor Assays | 2021 |