Page last updated: 2024-08-22

benoxaprofen and sulindac

benoxaprofen has been researched along with sulindac in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (52.94)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Kumar, M; Sinha, VR; Thareja, S1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Brater, DC; Campbell, WB; Henrich, WL1
Gallanosa, AG; Spyker, DA1
Rainsford, KD1
Bailey, PJ; Sturm, A1
Bigby, M; Stern, RS1
Faro, G; Michelotti, A; Sargiotto, A; Tarocco, RP1
Crabtree, RE; Johnson, DW; Ridolfo, AS; Rockhold, FW1
Roth, SH1

Reviews

3 review(s) available for benoxaprofen and sulindac

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Sulindac hepatotoxicity: a case report and review.
    Journal of toxicology. Clinical toxicology, 1985, Volume: 23, Issue:2-3

    Topics: Acetaminophen; Adolescent; Adult; Aged; Animals; Child; Drug Interactions; Enzyme Induction; Ethanol; Female; Humans; Indenes; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Propionates; Sulindac

1985
[Rheumatoid arthritis. Considerations on a rational therapeutic strategy].
    Minerva medica, 1984, Feb-28, Volume: 75, Issue:8

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumatoid; Azathioprine; Gold; Humans; Indomethacin; Levamisole; Penicillamine; Phenylbutazone; Propionates; Salicylates; Sulindac; Tolmetin

1984

Trials

2 trial(s) available for benoxaprofen and sulindac

ArticleYear
Gastrointestinal microbleeding: comparisons between benoxaprofen and other nonsteroidal antiinflammatory agents.
    The Journal of rheumatology. Supplement, 1980, Volume: 6

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzoxazoles; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Hemorrhage; Humans; Indomethacin; Melena; Naproxen; Propionates; Prostaglandins; Sulindac; Time Factors

1980
A comparison of benoxaprofen and sulindac in patients with rheumatoid arthritis and osteoarthritis.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indenes; Male; Middle Aged; Osteoarthritis; Propionates; Sulindac; Time Factors

1982

Other Studies

12 other study(ies) available for benoxaprofen and sulindac

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Renal hemodynamic effects of therapeutic plasma levels of sulindac sulfide during hemorrhage.
    Kidney international, 1986, Volume: 29, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dogs; Glomerular Filtration Rate; Hemodynamics; Hemorrhage; Indenes; Indomethacin; Ischemia; Kidney; Kidney Diseases; Propionates; Renal Circulation; Sulindac

1986
Structural damage and changes in eicosanoid metabolites in the gastric mucosa of rats and pigs induced by anti-inflammatory drugs of varying ulcerogenicity.
    International journal of tissue reactions, 1986, Volume: 8, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Diflunisal; Gastric Mucosa; Indomethacin; Membrane Potentials; Microscopy, Electron; Phenylacetates; Piroxicam; Propionates; Prostaglandins; Rats; Stomach Ulcer; Sulindac; Swine; Thiazines

1986
Immune complexes and inflammation. A study of the activity of anti-inflammatory drugs in the reverse passive arthus reaction in the rat.
    Biochemical pharmacology, 1983, Feb-01, Volume: 32, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arachidonic Acid; Arachidonic Acids; Arthus Reaction; Dexamethasone; Indomethacin; Male; Neutrophils; Propionates; Rats; Rats, Inbred Strains; Sulindac

1983
An expanded profile of cutaneous reactions to nonsteroidal anti-inflammatory drugs. Reports to a specialty-based system for spontaneous reporting of adverse reactions to drugs.
    JAMA, 1984, Sep-21, Volume: 252, Issue:11

    Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Meclofenamic Acid; Photosensitivity Disorders; Piroxicam; Propionates; Stevens-Johnson Syndrome; Sulindac; Thiazines; Tolmetin

1984