benextramine and phenoxybenzamine

benextramine has been researched along with phenoxybenzamine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's5 (33.33)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lafontan, M; Langin, D; Paris, H1
Black, JW; Shankley, NP1
Furnace, G; Hamilton, CA; Reid, JL; Sumner, DJ1
Nichols, AJ; Ruffolo, RR1
Hirst, GD; Lew, MJ1
Galitzky, J; Paris, H; Taouis, M1
de Jonge, A; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
Kirpekar, SM1
Angus, JA; Lew, MJ1
Belleau, B; Benfey, BG; Brasili, L; Melchiorre, C1
Amobi, NI; Smith, IC1
Badia, A; Sallés, J1
Docherty, JR; Kearns, S; O'Rourke, M1
Bodenstein, J; Brink, CB; Venter, DP1
Black, JW; Leff, P; Shankley, NP; Wood, J1

Reviews

1 review(s) available for benextramine and phenoxybenzamine

ArticleYear
Support for a role for feedback regulation of norepinephrine release.
    Federation proceedings, 1984, Volume: 43, Issue:5

    Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Cocaine; Cystamine; Diethylamines; Drug Synergism; Electric Stimulation; Ephedrine; Feedback; Naphthalenes; Norepinephrine; Phenoxybenzamine; Phentolamine; Prazosin; Receptors, Adrenergic, alpha; Sympathetic Nervous System; Synaptic Membranes

1984

Other Studies

14 other study(ies) available for benextramine and phenoxybenzamine

ArticleYear
Binding of [3H]idazoxan and of its methoxy derivative [3H] RX821002 in human fat cells: [3H]idazoxan but not [3H] RX821002 labels additional non-alpha 2-adrenergic binding sites.
    Molecular pharmacology, 1990, Volume: 37, Issue:6

    Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Binding Sites; Brimonidine Tartrate; Cell Membrane; Cystamine; Dioxanes; Dioxins; Epinephrine; Female; Humans; Idazoxan; Magnesium Chloride; Phenoxybenzamine; Potassium Chloride; Quinoxalines; Tritium; Yohimbine

1990
Interpretation of agonist affinity estimations: the question of distributed receptor states.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1990, Jun-22, Volume: 240, Issue:1299

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Cystamine; Kinetics; Mathematics; Models, Biological; Muscle, Smooth, Vascular; Pargyline; Phenoxybenzamine; Potassium Chloride; Rabbits; Receptors, Cell Surface; Serotonin

1990
Recovery of alpha-adrenoreceptor mediated responses and binding site number after intravenous benextramine in the rabbit.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Brain; Clonidine; Cystamine; Injections, Intravenous; Male; Membranes; Phenoxybenzamine; Phenylephrine; Prazosin; Rabbits; Receptors, Adrenergic, alpha; Spleen; Time Factors

1985
The relationship between alterations in alpha 1-adrenoceptor reserve by phenoxybenzamine and benextramine and the sensitivity of cirazoline-induced pressor responses to inhibition by nifedipine.
    European journal of pharmacology, 1986, Jul-31, Volume: 126, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cystamine; Denervation; Imidazoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha

1986
Lack of involvement of alpha-adrenoceptors in sympathetic neural vasoconstriction in the hindquarters of the rabbit.
    British journal of pharmacology, 1987, Volume: 90, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Cystamine; Electric Stimulation; Female; Gagging; Hindlimb; Male; Norepinephrine; Phenoxybenzamine; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Vasoconstriction

1987
In vitro study of alpha 2-adrenoceptor turnover and metabolism using the adenocarcinoma cell line HT29.
    Molecular pharmacology, 1987, Volume: 32, Issue:5

    Topics: Adenocarcinoma; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Cell Line; Cell Membrane; Colonic Neoplasms; Cyclic AMP; Cystamine; Kinetics; Phenoxybenzamine; Prazosin; Receptors, Adrenergic, alpha; Yohimbine

1987
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Imidazoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction

1985
Reversible inhibition of neuronal uptake by benextramine, an irreversible presynaptic alpha-adrenoceptor antagonist.
    European journal of pharmacology, 1984, Feb-10, Volume: 98, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Biogenic Amines; Cystamine; Desipramine; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Neurons; Norepinephrine; Phenoxybenzamine; Rabbits; Species Specificity; Sympathetic Nervous System

1984
Reactivation by cysteamine of vascular alpha adrenoceptors blocked by the tetramine disulfide benextramine and interaction of benextramine with phenoxybenzamine.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:12

    Topics: Animals; Aorta; Cystamine; Cysteamine; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardial Contraction; Norepinephrine; Phenoxybenzamine; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha

1980
Differential inhibition in the human vas deferens by phenoxybenzamine: a possible mechanism for its contraceptive action.
    Journal of reproduction and fertility, 1995, Volume: 103, Issue:2

    Topics: Adrenergic alpha-Antagonists; Calcium; Clonidine; Contraceptive Agents, Male; Cystamine; Humans; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Phenoxybenzamine; Prazosin; Vas Deferens

1995
Selective enrichment with alpha 1A- and alpha 1B-adrenoceptor subtypes in rat brain cortical membranes.
    European journal of pharmacology, 1994, Feb-15, Volume: 266, Issue:3

    Topics: Adrenergic alpha-Antagonists; Alkylating Agents; Alkylation; Animals; Binding Sites; Cerebral Cortex; Clonidine; Cystamine; Dihydropyridines; Dioxanes; Phenoxybenzamine; Phentolamine; Prazosin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha

1994
Investigation of the actions of chloroethylclonidine in rat aorta.
    British journal of pharmacology, 1995, Volume: 115, Issue:8

    Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Aorta; Clonidine; Cystamine; Dioxanes; Dose-Response Relationship, Drug; Drug Synergism; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxathiins; Phenoxybenzamine; Phentolamine; Piperazines; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Spiperone; Xylazine; Yohimbine

1995
Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cyclic AMP; Cystamine; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Humans; Inositol Phosphates; Ligands; Phenoxybenzamine; Piperidines; Receptor, Serotonin, 5-HT2A; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Second Messenger Systems; Serotonin Receptor Agonists; Signal Transduction

2005
An operational model of pharmacological agonism: the effect of E/[A] curve shape on agonist dissociation constant estimation. 1985.
    British journal of pharmacology, 2010, Volume: 160 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Cystamine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; History, 20th Century; In Vitro Techniques; Male; Models, Theoretical; Pharmacokinetics; Phenoxybenzamine; Rabbits; Receptors, Drug; Serotonin; Serotonin Agents

2010