befloxatone has been researched along with oxazoles in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 19 (59.38) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 6 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Armand, P; Berlin, I; Caille, P; Durrieu, G; Fitoussi, S; Molinier, P; Patat, A | 1 |
| Blier, P; Bouchard, C | 1 |
| Ducrey, F; Durant, F; Evrard, G; Jarreau, FX; Koenig, JJ; Moureau, F; Vercauteren, DP; Wouters, J | 1 |
| Caille, D; Curet, O; Ego, D; Jarreau, FX; Rovei, V | 1 |
| Curet, O; Damoiseau, G; Jarreau, FX; Labaune, JP; Rovel, V | 1 |
| Aubin, N; Curet, O; Damoiseau, G; Jarreau, FX; Rovei, V; Sontag, N | 1 |
| Adam, R; Bergis, OE; Caille, D; Charieras, T; Fankhauser, C; Gardes, A; Grosset, A; Jarreau, FX; Rovei, V | 1 |
| Blier, P; Piñeyro, G | 1 |
| Allain, H; Cimarosti, I; Curet, O; Dubruc, C; Durrieu, G; Gandon, JM; Jezequel, S; le Coz, F; Patat, A; Rosenzweig, P; Zieleniuk, I | 1 |
| Caille, P; Curet, O; Dago, KT; Durieu, G; Granier, LA; Luthringer, R; Macher, JP; Patat, A; Rinaudo, G; Toussaint, M | 1 |
| Berlin, I; Durrieu, G; Patat, A; Puech, AJ; Warot, D; Zieleniuk, I | 1 |
| Griebel, G; Perrault, G; Sanger, DJ | 1 |
| Blier, P; Curet, O; De Montigny, C; Haddjeri, N | 1 |
| Allain, H; Cimarosti, I; Gandon, JM; Patat, A; Rosenzweig, P; Zieleniuk, I | 1 |
| Blier, P; de Montigny, C; Haddjeri, N | 1 |
| Avenet, P; Bergis, O; Caille, D; Curet, O; Damoiseau-Ovens, G; Depoortere, H; Sauvage, C; Scatton, B; Sontag, N | 1 |
| Curet, O; Dubruc, C; Durrieu, G; Legangneux, E; Patat, A; Rosenzweig, P; Zieleniuk, I | 1 |
| Moser, PC; Sanger, DJ | 1 |
| Durant, F; Evrard, G; George, P; Jegham, S; Koenig, JJ; Moureau, F; Wouters, J | 1 |
| Dresse, A; Gerardy, J | 1 |
| Hunter, DJ; Ramsay, RR | 1 |
| Bottlaender, M; Bramoulle, Y; Curet, O; Dolle, F; Fuseau, C; George, P; Guenther, I; Jegham, J; Pinquier, JL; Roumenov, D; Valette, H | 1 |
| Bottlaender, M; Bramoulle, Y; Coulon, C; Curet, O; Dolle, F; Fuseau, C; George, P; Guenther, I; Jegham, S; Lartizien, C; Pinquier, JL; Valette, H | 1 |
| Bottlaender, M; Coulon, C; Dollé, F; Ottaviani, M; Syrota, A; Valette, H | 1 |
| Chait, A; de Beaurepaire, R; Molimard, R; Rat, P; Touiki, K | 1 |
| Artiges, E; Berlin, I; Bottlaender, M; Bourgeois, S; Bragulat, V; Dollé, F; Grégoire, MC; Leroy, C; Martinot, JL; Penttilä, J; Roumenov, D; Trichard, C | 1 |
| Bottlaender, M; Curet, O; Delforge, J; Dollé, F; George, P; Grégoire, MC; Guenther, I; Saba, W; Valette, H | 1 |
| Akao, Y; Inaba-Hasegawa, K; Maruyama, W; Naoi, M | 1 |
| Abe, Y; Iwasa, S; Narayama, A; Shibatomi, K | 1 |
| Boisgard, R; Cisternino, S; Dollé, F; Goutal, S; Hosten, B; Jacob, A; Saubaméa, B; Scherrmann, JM; Tournier, N | 1 |
| Bottlaender, M; Leroy, C; Martinot, JL; Rizzo, G; Roumenov, D; Trichard, C; Zanotti-Fregonara, P | 1 |
| Jiang, Y; Liu, R; Men, H; Shao, W; Shu, S; Zhang, W | 1 |
1 review(s) available for befloxatone and oxazoles
| Article | Year |
|---|---|
Preclinical profile of befloxatone, a new reversible MAO-A inhibitor.
Topics: Animals; Autoradiography; Autoreceptors; Brain; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Locus Coeruleus; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Protein Binding; Radiography; Raphe Nuclei; Rats; Receptors, Drug; Receptors, Neurotransmitter; Tissue Distribution | 1998 |
6 trial(s) available for befloxatone and oxazoles
| Article | Year |
|---|---|
Pharmacodynamics and pharmacokinetics of two dose regimens of befloxatone, a new reversible and selective monoamine oxidase inhibitor, at steady state in healthy volunteers.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Humans; Male; Metabolic Clearance Rate; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Oxazoles | 1996 |
Pharmacoelectroencephalographic profile of befloxatone, a new reversible MAO-A inhibitor, in healthy subjects.
Topics: Adult; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Female; Humans; Male; Monoamine Oxidase Inhibitors; Oxazoles | 1996 |
Effects of befloxatone, a reversible selective monoamine oxidase-A inhibitor, on psychomotor function and memory in healthy subjects.
Topics: Adult; Amitriptyline; Antidepressive Agents; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Humans; Male; Memory; Monoamine Oxidase Inhibitors; Oxazoles; Psychomotor Performance | 1996 |
Cognitive performance in elderly subjects after a single dose of befloxatone, a new reversible selective monoamine oxidase A inhibitor.
Topics: Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Cognition; Cross-Over Studies; Depression; Double-Blind Method; Female; Humans; Male; Monoamine Oxidase Inhibitors; Oxazoles; Psychomotor Performance; Reference Values | 1998 |
Clinical pharmacology of befloxatone: a brief review.
Topics: Adult; Aged; Brain; Cognition; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Humans; Methoxyhydroxyphenylglycol; Middle Aged; Monoamine Oxidase Inhibitors; Oxazoles; Placebos; Psychomotor Performance; Tyramine | 1998 |
Imaging of monoamine oxidase-A in the human brain with [11C]befloxatone: quantification strategies and correlation with mRNA transcription maps.
Topics: Adult; Brain; Carbon Radioisotopes; Gene Expression Regulation, Enzymologic; Humans; Male; Monoamine Oxidase; Oxazoles; Positron-Emission Tomography; RNA, Messenger; Transcription, Genetic | 2014 |
25 other study(ies) available for befloxatone and oxazoles
| Article | Year |
|---|---|
Pressor effect of oral tyramine during treatment with befloxatone, a new reversible monoamine oxidase-A inhibitor, in healthy subjects.
Topics: Adult; Drug Administration Schedule; Drug Interactions; Humans; Male; Monoamine Oxidase Inhibitors; Oxazoles; Pressoreceptors; Single-Blind Method; Tyramine | 1995 |
Modulation of 5-HT release in the guinea-pig brain following long-term administration of antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Electric Stimulation; Frontal Lobe; Guinea Pigs; Hippocampus; Hypothalamus; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Nerve Endings; Oxazoles; Paroxetine; Perfusion; Receptors, Adrenergic, alpha-2; Serotonin; Serotonin Receptor Agonists | 1994 |
Experimental and theoretical study of reversible monoamine oxidase inhibitors: structural approach of the active site of the enzyme.
Topics: Chemical Phenomena; Chemistry, Physical; Models, Chemical; Monoamine Oxidase Inhibitors; Oxazoles; Structure-Activity Relationship; X-Ray Diffraction | 1994 |
Biochemical pharmacology of befloxatone (MD370503), a new potent reversible MAO-A inhibitor.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Brain; Drug Interactions; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Rats; Rats, Sprague-Dawley; Tyramine | 1994 |
Effects of befloxatone, a new potent reversible MAO-A inhibitor, on cortex and striatum monoamines in freely moving rats.
Topics: Animals; Biogenic Monoamines; Cerebral Cortex; Corpus Striatum; Dopamine; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nialamide; Norepinephrine; Oxazoles; Pargyline; Rats; Rats, Sprague-Dawley; Serotonin | 1994 |
Befloxatone, a new reversible and selective monoamine oxidase-A inhibitor. I. Biochemical profile.
Topics: Animals; Biogenic Monoamines; Brain; Duodenum; Humans; Liver; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Oxazoles; Rats; Rats, Sprague-Dawley | 1996 |
Befloxatone, a new reversible and selective monoamine oxidase-A inhibitor. II. Pharmacological profile.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Cholinergic Antagonists; Male; Mice; Monoamine Oxidase Inhibitors; Motor Activity; Oxazoles; Rats; Rats, Sprague-Dawley; Sleep, REM; Swimming; Tyramine | 1996 |
Regulation of 5-hydroxytryptamine release from rat midbrain raphe nuclei by 5-hydroxytryptamine1D receptors: effect of tetrodotoxin, G protein inactivation and long-term antidepressant administration.
Topics: Animals; Antidepressive Agents; GTP-Binding Proteins; Male; Oxazoles; Paroxetine; Potassium; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Sumatriptan; Tetrodotoxin | 1996 |
Behavioural profiles of the reversible monoamine-oxidase-A inhibitors befloxatone and moclobemide in an experimental model for screening anxiolytic and anti-panic drugs.
Topics: Animals; Anxiety; Avoidance Learning; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Oxazoles; Panic Disorder; Rats | 1997 |
Effect of the reversible monoamine oxidase-A inhibitor befloxatone on the rat 5-hydroxytryptamine neurotransmission.
Topics: Afferent Pathways; Animals; Electric Stimulation; Hippocampus; Locus Coeruleus; Male; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Oxazoles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Synaptic Transmission | 1998 |
Long-term antidepressant treatments result in a tonic activation of forebrain 5-HT1A receptors.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Electrophysiology; Excitatory Amino Acid Agonists; Hippocampus; Inhibition, Psychological; Male; Mianserin; Mirtazapine; Monoamine Oxidase Inhibitors; Oxazoles; Pertussis Toxin; Piperazines; Prosencephalon; Pyramidal Cells; Pyridines; Pyrimidines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Virulence Factors, Bordetella | 1998 |
5-HT1A receptor antagonists neither potentiate nor inhibit the effects of fluoxetine and befloxatone in the forced swim test in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Drug Interactions; Fluoxetine; Male; Monoamine Oxidase Inhibitors; Oxazoles; Pindolol; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Swimming | 1999 |
A reversible monoamine oxidase A inhibitor, befloxatone: structural approach of its mechanism of action.
Topics: Animals; Crystallography, X-Ray; Hydrogen Bonding; Male; Molecular Conformation; Monoamine Oxidase Inhibitors; Oxazoles; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1999 |
Comparative effects of dehydropirlindole and other compounds on rat brain monoamine oxidase type A.
Topics: Animals; Brain; Carbazoles; Clorgyline; Harmaline; Kinetics; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Rats; Rats, Wistar | 2002 |
Inhibitors alter the spectrum and redox properties of monoamine oxidase A.
Topics: Carbazoles; Cloning, Molecular; Dextroamphetamine; Dithionite; Harmine; Humans; Liver; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Oxidation-Reduction; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry | 2002 |
Mapping the cerebral monoamine oxidase type A: positron emission tomography characterization of the reversible selective inhibitor [11C]befloxatone.
Topics: Animals; Biotransformation; Brain; Brain Mapping; Dose-Response Relationship, Drug; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Papio; Tomography, Emission-Computed | 2003 |
Synthesis and in vivo imaging properties of [11C]befloxatone: a novel highly potent positron emission tomography ligand for mono-amine oxidase-A.
Topics: Animals; Brain; Carbon Radioisotopes; Ligands; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Papio; Radiopharmaceuticals; Tissue Distribution; Tomography, Emission-Computed | 2003 |
Acute inhibition of cardiac monoamine oxidase A after tobacco smoke inhalation: validation study of [11C]befloxatone in rats followed by a positron emission tomography application in baboons.
Topics: Algorithms; Animals; Chromatography, High Pressure Liquid; Heart; Injections, Intravenous; Isotope Labeling; Ligands; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Myocardium; Nicotiana; Nicotine; Nicotinic Agonists; Oxazoles; Papio; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Smoke; Sympathetic Nervous System; Tissue Distribution; Ventricular Function, Left | 2005 |
Harmane inhibits serotonergic dorsal raphe neurons in the rat.
Topics: Action Potentials; Analysis of Variance; Animals; Carbolines; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Harmine; Male; Neurons; Neurotoxins; Nicotine; Nicotinic Agonists; Oxazoles; Phenethylamines; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Antagonists | 2005 |
Cerebral monoamine oxidase A inhibition in tobacco smokers confirmed with PET and [11C]befloxatone.
Topics: Adult; Carbon Radioisotopes; Cerebral Cortex; Humans; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nicotine; Nicotinic Agonists; Oxazoles; Positron-Emission Tomography; Radiopharmaceuticals; Smoking; Tissue Distribution | 2009 |
In vivo quantification of monoamine oxidase A in baboon brain: a PET study using [(11)C]befloxatone and the multi-injection approach.
Topics: Animals; Binding Sites; Brain; Brain Mapping; Carbon Radioisotopes; Cerebrovascular Circulation; Humans; Isotope Labeling; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Oxazoles; Papio; Positron-Emission Tomography; Radiopharmaceuticals; Regional Blood Flow | 2010 |
Type A monoamine oxidase is associated with induction of neuroprotective Bcl-2 by rasagiline, an inhibitor of type B monoamine oxidase.
Topics: Analysis of Variance; Cell Line, Tumor; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Indans; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Oxazoles; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Selegiline; Transfection; Up-Regulation | 2012 |
Practical synthesis of 4,4,4-trifluorocrotonaldehyde: a versatile precursor for the enantioselective formation of trifluoromethylated stereogenic centers via organocatalytic 1,4-additions.
Topics: Aldehydes; Catalysis; Monoamine Oxidase Inhibitors; Oxazoles; Stereoisomerism | 2012 |
[¹¹C]befloxatone brain kinetics is not influenced by Bcrp function at the blood-brain barrier: a PET study using Bcrp TGEM knockout rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Brain; Male; Oxazoles; Positron-Emission Tomography; Rats; Rats, Transgenic; Rats, Wistar | 2013 |
Monoamine oxidase inhibitors protect against coronary heart disease in rodent rat models: A pilot study.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Hemodynamics; Male; Monoamine Oxidase Inhibitors; Myocardium; Oxazoles; Rats, Wistar | 2019 |