be-14106 has been researched along with stubomycin* in 1 studies
1 other study(ies) available for be-14106 and stubomycin
Article | Year |
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Aureoverticillactam, a novel 22-atom macrocyclic lactam from the marine actinomycete Streptomyces aureoverticillatus.
During the course of our screening program designed to discover novel anticancer and anti-infective agents from marine microorganisms, a strain of Streptomyces aureoverticillatus (NPS001583) isolated from a marine sediment was found to produce a novel macrocyclic lactam with cytotoxicity against various tumor cell lines. Using extensive MS, UV, and NMR spectral analyses, the structure has been established as compound 1, aureoverticillactam, a 22-atom macrocyclic lactam incorporating both triene and tetraene conjugated olefins. Topics: Actinobacteria; Alkenes; Aminoglycosides; Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Lactams; Macrolides; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Polyenes; Streptomyces; Tumor Cells, Cultured | 2004 |