Page last updated: 2024-09-04

bdp 12 and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

bdp 12 has been researched along with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid in 5 studies

Compound Research Comparison

Studies
(bdp 12)
Trials
(bdp 12)
Recent Studies (post-2010)
(bdp 12)
Studies
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Trials
(alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
Recent Studies (post-2010) (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)
627142,89911609

Protein Interaction Comparison

ProteinTaxonomybdp 12 (IC50)alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (IC50)
Glutamate receptor 1Rattus norvegicus (Norway rat)0.157
Glutamate receptor 2Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 3Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 4Rattus norvegicus (Norway rat)0.1765
Glutamate receptor 1Mus musculus (house mouse)0.04
Glutamate receptor 2Mus musculus (house mouse)0.04
Glutamate receptor 1Homo sapiens (human)0.1353
Glutamate receptor 2Homo sapiens (human)0.1353
Glutamate receptor 3Homo sapiens (human)0.1353
Glutamate receptor 4Homo sapiens (human)0.1353
Glutamate receptor 4Mus musculus (house mouse)0.04
Glutamate receptor 3Mus musculus (house mouse)0.04

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Black, MD; Hanak, SE; Schilp, DE; Sorensen, SM; Wettstein, JG; Wotanis, J1
Bódi, I; Gueritaud, J; Kapus, G; Pataki, A; Székely, JI; Tarnawa, I1
Bond, A; Huff, K; Lodge, D; Vandergriff, J1
Baumbarger, PJ; Muhlhauser, M; Nisenbaum, ES; Yang, CR; Zhai, J1
Baumbarger, P; Bleakman, D; Gates, M; Hicks, CA; Lodge, D; Murray, TK; Nisenbaum, ES; O'Neill, MJ; Ogden, AM; Robinson, CS; Siuda, E; Skolnick, P; Vandergriff, JL; Ward, MA; Whalley, K; Zimmerman, DM1

Other Studies

5 other study(ies) available for bdp 12 and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

ArticleYear
Effect of AMPA receptor modulators on hippocampal and cortical function.
    European journal of pharmacology, 2000, Apr-07, Volume: 394, Issue:1

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebral Cortex; Dioxoles; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Piperidines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, AMPA

2000
Differential modulation of the GYKI 53784-induced inhibition of AMPA currents by various AMPA-positive modulators in cerebellar Purkinje cells.
    European journal of pharmacology, 2000, May-26, Volume: 397, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Benzothiadiazines; Cells, Cultured; Cerebellum; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Antagonists; Membrane Potentials; Piperidines; Purkinje Cells; Pyrrolidinones; Rats; Receptors, AMPA

2000
Potentiation of responses to AMPA on central neurones by LY392098 and LY404187 in vivo.
    Neuropharmacology, 2001, Volume: 40, Issue:8

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Dioxoles; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Amino Acid Agonists; Female; Hippocampus; Injections, Intravenous; Male; Neurons; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Spinal Cord; Stereotaxic Techniques; Sulfonamides; Thiophenes

2001
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:1

    Topics: Allosteric Regulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzodiazepines; Dioxoles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Male; Piperidines; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Sulfonamides

2001
LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amides; Animals; Biphenyl Compounds; Cells, Cultured; Corpus Striatum; Dioxoles; Disease Models, Animal; Excitatory Amino Acid Agonists; GAP-43 Protein; Hippocampus; Humans; Male; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Substantia Nigra

2003