Page last updated: 2024-09-05

bd 1047 and dextromethorphan

bd 1047 has been researched along with dextromethorphan in 5 studies

Compound Research Comparison

Studies
(bd 1047)
Trials
(bd 1047)
Recent Studies (post-2010)
(bd 1047)
Studies
(dextromethorphan)
Trials
(dextromethorphan)
Recent Studies (post-2010) (dextromethorphan)
1180542,020342593

Protein Interaction Comparison

ProteinTaxonomybd 1047 (IC50)dextromethorphan (IC50)
Sodium channel protein type 1 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 2 subunit alphaRattus norvegicus (Norway rat)1.3
Sodium channel protein type 3 subunit alphaRattus norvegicus (Norway rat)1.3
Cytochrome P450 2D26Rattus norvegicus (Norway rat)5.6
Cytochrome P450 2D6Homo sapiens (human)2.1768
Sodium-dependent serotonin transporterHomo sapiens (human)0.0027
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.1236

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, C; Ellis, JL; Fezoui, M; Schwartz, CE; Selig, WM1
Baeyens, JM; Cobos, EJ; Del Pozo, E1
Baek, IH; Bing, G; Chae, JS; Kim, HC; Kim, WK; Maurice, T; Nabeshima, T; Nah, SY; Shin, EJ; Shin, SW; Yen, TP1
Chen, SL; Hsu, KY; Huang, EY; Lu, RB; Tao, PL1
Healy, JR; Matsumoto, RR; Nguyen, L; Robson, MJ; Scandinaro, AL1

Other Studies

5 other study(ies) available for bd 1047 and dextromethorphan

ArticleYear
Antitussive activity of sigma-1 receptor agonists in the guinea-pig.
    British journal of pharmacology, 2004, Volume: 141, Issue:2

    Topics: Animals; Antitussive Agents; Brain; Cough; Dextromethorphan; Dose-Response Relationship, Drug; Ethylenediamines; Guinea Pigs; Male; Phenazocine; Protein Binding; Receptors, sigma; Sigma-1 Receptor

2004
Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain.
    Synapse (New York, N.Y.), 2005, Mar-01, Volume: 55, Issue:3

    Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Binding, Competitive; Brain; Dextromethorphan; Drug Interactions; Ethylenediamines; Guinea Pigs; Haloperidol; Ligands; Male; Morpholines; Neurons; Phenazocine; Phenytoin; Piperazines; Piperidines; Progesterone; Propylamines; Receptors, sigma; Synaptic Transmission

2005
Dextromethorphan attenuates trimethyltin-induced neurotoxicity via sigma1 receptor activation in rats.
    Neurochemistry international, 2007, Volume: 50, Issue:6

    Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Behavior, Animal; Dextromethorphan; Ethylenediamines; Immunohistochemistry; Learning Disabilities; Maze Learning; Memory; Nerve Degeneration; Neurotoxicity Syndromes; Piperidines; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Phencyclidine; Receptors, sigma; Seizures; Sigma-1 Receptor; Trimethyltin Compounds

2007
Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats.
    Drug and alcohol dependence, 2011, Sep-01, Volume: 117, Issue:2-3

    Topics: Analgesics, Opioid; Animals; Antitussive Agents; Behavior, Animal; Conditioning, Psychological; Dextromethorphan; Dose-Response Relationship, Drug; Ethylenediamines; Male; Morphine; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reward; Sigma-1 Receptor; Ventral Tegmental Area

2011
Involvement of sigma-1 receptors in the antidepressant-like effects of dextromethorphan.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Dose-Response Relationship, Drug; Ethylenediamines; Excitatory Amino Acid Antagonists; Ketamine; Kinetics; Male; Mice; Piperazines; Protein Binding; Quinidine; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Swimming

2014