bd 1008 has been researched along with cocaine in 7 studies
| Studies (bd 1008) | Trials (bd 1008) | Recent Studies (post-2010) (bd 1008) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 28 | 0 | 4 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | bd 1008 (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowen, WD; Matsumoto, RR; McCracken, KA | 1 |
| Bowen, WD; De Costa, BR; Matsumoto, RR; McCracken, KA; Miller, J; Pouw, B; Williams, W | 1 |
| Bowen, WD; De Costa, BR; Friedman, MJ; Matsumoto, RR; McCracken, KA; Pouw, B | 1 |
| Bowen, WD; Cao, JJ; Hewett, KL; Husbands, SM; Matsumoto, RR; Newman, AH; Pouw, B | 1 |
| Bowen, WD; Matsumoto, RR; McCracken, KA; Pouw, B; Zhang, Y | 1 |
| Bowen, WD; Coop, A; Gilmore, DL; Kausar, A; Matsumoto, RR; Pouw, B; Williams, W | 1 |
| Garcés-Ramírez, L; Green, JL; Hiranita, T; Katz, JL; Kopajtic, TA; McCurdy, CR; Mereu, M; Mesangeau, C; Narayanan, S; Tanda, G; Thomas, AM | 1 |
7 other study(ies) available for bd 1008 and cocaine
| Article | Year |
|---|---|
Novel sigma receptor ligands attenuate the locomotor stimulatory effects of cocaine.
Topics: Animals; Binding, Competitive; Cocaine; Dopamine Uptake Inhibitors; Ethylamines; Guinea Pigs; Male; Mice; Motor Activity; Piperazines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Phencyclidine; Receptors, Serotonin; Receptors, sigma | 1999 |
N-alkyl substituted analogs of the sigma receptor ligand BD1008 and traditional sigma receptor ligands affect cocaine-induced convulsions and lethality in mice.
Topics: Alkylation; Animals; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ethylamines; Guinea Pigs; In Vitro Techniques; Injections, Intraventricular; Ligands; Male; Mice; Microinjections; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Red Nucleus; Seizures | 2001 |
Conformationally restricted analogs of BD1008 and an antisense oligodeoxynucleotide targeting sigma1 receptors produce anti-cocaine effects in mice.
Topics: Analysis of Variance; Animals; Binding, Competitive; Cocaine; Ethylamines; Locomotion; Male; Mice; Motor Activity; Oligodeoxyribonucleotides, Antisense; Piperazines; Pyrrolidines; Receptors, sigma; Seizures; Structure-Activity Relationship | 2001 |
Rimcazole analogs attenuate the convulsive effects of cocaine: correlation with binding to sigma receptors rather than dopamine transporters.
Topics: Animals; Anticonvulsants; Binding Sites; Carbazoles; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Ethylamines; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Seizures | 2001 |
Involvement of sigma receptors in the behavioral effects of cocaine: evidence from novel ligands and antisense oligodeoxynucleotides.
Topics: Animals; Cocaine; Dose-Response Relationship, Drug; Ethylamines; Guinea Pigs; Ligands; Male; Mice; Motor Activity; Oligodeoxyribonucleotides, Antisense; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Seizures | 2002 |
Novel analogs of the sigma receptor ligand BD1008 attenuate cocaine-induced toxicity in mice.
Topics: Animals; Binding, Competitive; Brain; Cocaine; Ethylamines; Guinea Pigs; Ligands; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Seizures | 2004 |
Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis.
Topics: Animals; Benzoxazoles; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Ethylamines; Ethylenediamines; Guanidines; Male; Microdialysis; Morpholines; Nucleus Accumbens; Piperazines; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Synaptic Transmission | 2011 |