bd 1008 has been researched along with 1,3-ditolylguanidine in 8 studies
| Studies (bd 1008) | Trials (bd 1008) | Recent Studies (post-2010) (bd 1008) | Studies (1,3-ditolylguanidine) | Trials (1,3-ditolylguanidine) | Recent Studies (post-2010) (1,3-ditolylguanidine) |
|---|---|---|---|---|---|
| 28 | 0 | 4 | 357 | 0 | 71 |
| Protein | Taxonomy | bd 1008 (IC50) | 1,3-ditolylguanidine (IC50) |
|---|---|---|---|
| polyadenylate-binding protein 1 | Homo sapiens (human) | 19.8 | |
| Rev | Human immunodeficiency virus 1 | 8.312 | |
| Female germline-specific tumor suppressor gld-1 | Caenorhabditis elegans | 5.205 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.036 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.1816 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bowen, W; de Costa, BR; Dominguez, C; He, XS; Radesca, L; Williams, W | 1 |
| Calderon, SN; Gutkind, JS; Heller, B; Izenwasser, S; Mattson, MV; Newman, AH; Su, TP | 1 |
| Ablordeppey, SY; el-Ashmawy, MB; Fischer, JB; Glennon, RA; Howie, KB; Ismaiel, AM | 1 |
| Bowen, WD; Cutts, J; de Costa, BR; Dominguez, C; He, XS; Williams, W | 1 |
| Bowen, WD; de Costa, BR; Dominguez, C; Gu, ZQ; He, XS; Linders, JT; Williams, W | 1 |
| De Costa, BR; Martin, WJ; Walker, JM | 1 |
| Maurice, T; Nabeshima, T; Noda, Y; Phan, VL; Privat, A; Yamada, K | 1 |
| Garcés-Ramírez, L; Green, JL; Hiranita, T; Katz, JL; Kopajtic, TA; McCurdy, CR; Mereu, M; Mesangeau, C; Narayanan, S; Tanda, G; Thomas, AM | 1 |
8 other study(ies) available for bd 1008 and 1,3-ditolylguanidine
| Article | Year |
|---|---|
Synthesis and biological evaluation of conformationally restricted 2-(1-pyrrolidinyl)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methylethylenediam ines as sigma receptor ligands. 1. Pyrrolidine, piperidine, homopiperidine, and tetrahydroisoquinoline classes.
Topics: Animals; Ethylenediamines; Guinea Pigs; Isoquinolines; Molecular Conformation; Piperidines; Pyrrolidines; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship | 1992 |
Novel 1-phenylcycloalkanecarboxylic acid derivatives are potent and selective sigma 1 ligands.
Topics: Animals; Anticonvulsants; Antitussive Agents; Binding Sites; Cyclopentanes; In Vitro Techniques; Male; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Receptors, sigma; Structure-Activity Relationship | 1994 |
Structural features important for sigma 1 receptor binding.
Topics: Alkylation; Amines; Animals; Binding Sites; Brain; Cell Membrane; Cyclization; Guinea Pigs; Methylation; Molecular Structure; Receptors, sigma; Stereoisomerism; Structure-Activity Relationship | 1994 |
A new approach to the design of sigma-2-selective ligands: synthesis and evaluation of N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1- pyrrolidinyl)ethylamine-related polyamines at sigma-1 and sigma-2 receptor subtypes.
Topics: Animals; Binding Sites; Brain; Drug Design; Ethylamines; Guinea Pigs; In Vitro Techniques; Ligands; Liver; Male; Molecular Structure; Polyamines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1994 |
Synthesis and evaluation of conformationally restricted N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamines at sigma receptors. 2. Piperazines, bicyclic amines, bridged bicyclic amines, and miscellaneous compounds.
Topics: Animals; Brain; Ethylamines; Guinea Pigs; Receptors, sigma; Structure-Activity Relationship | 1993 |
Effects of sigma ligands on rat cerebellar Purkinje neuron firing: an iontophoretic study.
Topics: Animals; Ethylamines; Guanidines; Iontophoresis; Levallorphan; Male; Pentazocine; Piperidines; Purkinje Cells; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, sigma | 1994 |
The attenuation of learning impairments induced after exposure to CO or trimethyltin in mice by sigma (sigma) receptor ligands involves both sigma1 and sigma2 sites.
Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Carbon Monoxide; Ethylamines; Guanidines; Haloperidol; Learning Disabilities; Ligands; Male; Memory Disorders; Mice; Pyrrolidines; Receptors, sigma; Sigma-1 Receptor; Trimethyltin Compounds | 1999 |
Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis.
Topics: Animals; Benzoxazoles; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Drug Interactions; Ethylamines; Ethylenediamines; Guanidines; Male; Microdialysis; Morpholines; Nucleus Accumbens; Piperazines; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Synaptic Transmission | 2011 |