Compounds > bazedoxifene
Page last updated: 2024-09-04

bazedoxifene and paclitaxel

bazedoxifene has been researched along with paclitaxel in 2 studies

Compound Research Comparison

Studies
(bazedoxifene)		Trials
(bazedoxifene)		Recent Studies (post-2010)
(bazedoxifene)		Studies
(paclitaxel)		Trials
(paclitaxel)		Recent Studies (post-2010) (paclitaxel)
3076924931,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomybazedoxifene (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Cao, Y; Chen, X; Fu, S; Lin, HJ; Lin, J; Lo, HW; Pan, L; Tian, J; Wu, X; Xiao, H; Zhang, R; Zhang, Y1
Heo, TH; Kim, HJ; Kim, LK; Park, HM; Park, SA1

Other Studies

2 other study(ies) available for bazedoxifene and paclitaxel

ArticleYear
Bazedoxifene is a novel IL-6/GP130 inhibitor for treating triple-negative breast cancer.
    Breast cancer research and treatment, 2019, Volume: 175, Issue:3

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cytokine Receptor gp130; Down-Regulation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Indoles; Interleukin-6; Mice; Paclitaxel; Phosphorylation; Signal Transduction; Triple Negative Breast Neoplasms; Xenograft Model Antitumor Assays

2019
Inhibition of GP130/STAT3 and EMT by combined bazedoxifene and paclitaxel treatment in ovarian cancer.
    Oncology reports, 2022, Volume: 47, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cytokine Receptor gp130; Drug Therapy, Combination; Epithelial-Mesenchymal Transition; Female; Glycoproteins; Humans; Indoles; Mice; Mice, Inbred BALB C; Ovarian Neoplasms; Paclitaxel; Selective Estrogen Receptor Modulators; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2022