Page last updated: 2024-09-04

bazedoxifene and medroxyprogesterone acetate

bazedoxifene has been researched along with medroxyprogesterone acetate in 5 studies

Compound Research Comparison

Studies
(bazedoxifene)
Trials
(bazedoxifene)
Recent Studies (post-2010)
(bazedoxifene)
Studies
(medroxyprogesterone acetate)
Trials
(medroxyprogesterone acetate)
Recent Studies (post-2010) (medroxyprogesterone acetate)
307692495,1231,1151,099

Protein Interaction Comparison

ProteinTaxonomybazedoxifene (IC50)medroxyprogesterone acetate (IC50)
Estrogen receptorHomo sapiens (human)0.924
Glucocorticoid receptorHomo sapiens (human)0.013
Progesterone receptorHomo sapiens (human)2.5081
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.019
Mineralocorticoid receptor Homo sapiens (human)1.197
Androgen receptorHomo sapiens (human)0.0061
Androgen receptorRattus norvegicus (Norway rat)0.279
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.019
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.019
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.019
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.197
Aldo-keto reductase family 1 member C3Homo sapiens (human)1.4059
Aldo-keto reductase family 1 member C2 Homo sapiens (human)4.0405
Aldo-keto reductase family 1 member C1Homo sapiens (human)1.8
Estrogen receptor betaHomo sapiens (human)0.924

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chines, AA; Komm, BS; Mirkin, S; Pan, K1
Bushmakin, AG; Cappelleri, JC; Chines, AA; Mirkin, S; Pinkerton, JV; Racketa, J1
Abraham, L; Chines, AA; Mirkin, S; Pan, K; Pinkerton, JV; Racketa, J; Ryan, KA1
Archer, DF; Chines, AA; Harvey, JA; Lindsay, R; Mirkin, S; Pan, K; Pinkerton, JV1
Abreu, P; Andrews, E; Kagan, R1

Trials

5 trial(s) available for bazedoxifene and medroxyprogesterone acetate

ArticleYear
Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women.
    Climacteric : the journal of the International Menopause Society, 2013, Volume: 16, Issue:3

    Topics: Adult; Bone Density; Bone Density Conservation Agents; Double-Blind Method; Endometrial Hyperplasia; Estrogens, Conjugated (USP); Female; Humans; Indoles; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis, Postmenopausal; Placebos; Postmenopause; Selective Estrogen Receptor Modulators

2013
Evaluation of the direct and indirect effects of bazedoxifene/conjugated estrogens on sleep disturbance using mediation modeling.
    Menopause (New York, N.Y.), 2014, Volume: 21, Issue:3

    Topics: Adult; Double-Blind Method; Estrogens, Conjugated (USP); Female; Hot Flashes; Humans; Indoles; Medroxyprogesterone Acetate; Middle Aged; Models, Statistical; Placebos; Postmenopause; Sleep Wake Disorders; Treatment Outcome

2014
Sleep parameters and health-related quality of life with bazedoxifene/conjugated estrogens: a randomized trial.
    Menopause (New York, N.Y.), 2014, Volume: 21, Issue:3

    Topics: Double-Blind Method; Estrogens, Conjugated (USP); Female; Health Status; Hot Flashes; Humans; Indoles; Medroxyprogesterone Acetate; Middle Aged; Placebos; Postmenopause; Quality of Life; Sleep; Sleep Wake Disorders; Surveys and Questionnaires

2014
Effects of bazedoxifene/conjugated estrogens on the endometrium and bone: a randomized trial.
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:2

    Topics: Adult; Aged; Bone Density; Bone Density Conservation Agents; Double-Blind Method; Drug Therapy, Combination; Endometrial Hyperplasia; Endometrium; Estrogens, Conjugated (USP); Female; Humans; Indoles; Lumbar Vertebrae; Medroxyprogesterone Acetate; Middle Aged; Selective Estrogen Receptor Modulators; Treatment Outcome

2014
Vaginal bleeding/spotting with conjugated estrogens/bazedoxifene, conjugated estrogens/medroxyprogesterone acetate, and placebo.
    Postgraduate medicine, 2018, Volume: 130, Issue:8

    Topics: Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Indoles; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Selective Estrogen Receptor Modulators; Uterine Hemorrhage

2018