bay y3118 has been researched along with ciprofloxacin in 10 studies
*Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline. [MeSH]
*Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline. [MeSH]
| Studies (bay y3118) | Trials (bay y3118) | Recent Studies (post-2010) (bay y3118) | Studies (ciprofloxacin) | Trials (ciprofloxacin) | Recent Studies (post-2010) (ciprofloxacin) |
|---|---|---|---|---|---|
| 37 | 0 | 0 | 16,060 | 1,331 | 6,092 |
| Protein | Taxonomy | bay y3118 (IC50) | ciprofloxacin (IC50) |
|---|---|---|---|
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | 0.41 | |
| DNA gyrase subunit B | Bacillus subtilis subsp. subtilis str. 168 | 6.3 | |
| DNA gyrase subunit A | Bacillus subtilis subsp. subtilis str. 168 | 6.3 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.31 | |
| DNA gyrase subunit B | Staphylococcus aureus | 4.32 | |
| DNA gyrase subunit A | Escherichia coli K-12 | 0.6845 | |
| DNA gyrase subunit B | Escherichia coli K-12 | 0.5632 | |
| DNA topoisomerase 4 subunit B | Staphylococcus aureus | 6.485 | |
| DNA topoisomerase 4 subunit A | Staphylococcus aureus | 4.8011 | |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.41 | |
| DNA gyrase subunit A | Staphylococcus aureus | 4.32 | |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | 0.41 | |
| DNA topoisomerase 4 subunit A | Bacillus subtilis subsp. subtilis str. 168 | 1.7 | |
| DNA topoisomerase 4 subunit B | Bacillus subtilis subsp. subtilis str. 168 | 1.7 | |
| GABA theta subunit | Rattus norvegicus (Norway rat) | 0.41 | |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | 0.41 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (90.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlyn, CJ; Doyle, LJ; Knapp, CC; Ludwig, MD; Washington, JA | 1 |
| Bauernfeind, A | 1 |
| Heilmann, HD; Sirgel, FA; Venter, A | 1 |
| Aldridge, KE | 1 |
| Borobio, MV; Conejo, M; Perea, EJ; Ramirez, E; Suarez, AI | 1 |
| Appelbaum, PC; Jacobs, MR; Pankuch, GA | 1 |
| Andrews, JM; Brenwald, N; Wise, R | 1 |
| Molinari, G; Schito, GC | 1 |
| Hof, H; Nichterlein, T; Walz, A | 1 |
| Castell, JV; Morlière, P; Ouédraogo, G; Santus, R | 1 |
10 other study(ies) available for bay y3118 and ciprofloxacin
| Article | Year |
|---|---|
Activities of three investigational fluoroquinolones (BAY y 3118, DU-6859a, and clinafloxacin) against Neisseria gonorrhoeae isolates with diminished susceptibilities to ciprofloxacin and ofloxacin.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Resistance, Microbial; Fluoroquinolones; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Ofloxacin; Quinolones; Spiro Compounds | 1995 |
Comparative in-vitro activities of the new quinolone, Bay y 3118, and ciprofloxacin, sparfloxacin, tosufloxacin, CI-960 and CI-990.
Topics: Anti-Infective Agents; Bacteria; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Quinolones | 1993 |
Comparative in-vitro activity of Bay y 3118, a new quinolone, and ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex.
Topics: Anti-Infective Agents; Ciprofloxacin; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Mycobacterium tuberculosis; Quinolones; Sputum; Tuberculosis, Pulmonary | 1995 |
Increased activity of a new chlorofluoroquinolone, BAY y 3118, compared with activities of ciprofloxacin, sparfloxacin, and other antimicrobial agents against anaerobic bacteria.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; Bacterial Infections; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones | 1994 |
Comparative activities of eight quinolones against members of the Bacteroides fragilis group.
Topics: Anti-Infective Agents; Bacteroides fragilis; Ciprofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1994 |
Susceptibilities of 428 gram-positive and -negative anaerobic bacteria to Bay y3118 compared with their susceptibilities to ciprofloxacin, clindamycin, metronidazole, piperacillin, piperacillin-tazobactam, and cefoxitin.
Topics: Anti-Infective Agents; Bacteria, Anaerobic; beta-Lactamases; Cefoxitin; Ciprofloxacin; Clindamycin; Drug Therapy, Combination; Fluoroquinolones; Gram-Negative Anaerobic Bacteria; Gram-Positive Bacteria; Metronidazole; Microbial Sensitivity Tests; Piperacillin | 1993 |
The in-vitro activity of Bay y 3118, a new chlorofluoroquinolone.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Chlamydia; Ciprofloxacin; Enterobacteriaceae; Fluoroquinolones; Lactams; Microbial Sensitivity Tests; Quinolones; Species Specificity; Staphylococcus | 1993 |
Comparative in vitro activity of BAY Y 3118 with other fluoroquinolones.
Topics: Aminoglycosides; Ampicillin Resistance; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Ciprofloxacin; Cross Infection; Drug Resistance, Microbial; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Ofloxacin; Quinolones | 1995 |
Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteriological Techniques; Ciprofloxacin; Colony Count, Microbial; Erythromycin; Fluoroquinolones; Gentamicins; Legionella pneumophila; Legionnaires' Disease; Macrophages; Mice; Penicillins; Quinolones; Tumor Cells, Cultured | 1997 |
Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones.
Topics: Anti-Infective Agents; Cells, Cultured; Ciprofloxacin; Cytoplasm; Fibroblasts; Fluoroquinolones; Humans; Mitochondria; Norfloxacin; Ofloxacin; Photosensitizing Agents; Quinolones; Skin | 2000 |