Page last updated: 2024-09-03

bay x 1005 and mocetinostat

bay x 1005 has been researched along with mocetinostat in 4 studies

Compound Research Comparison

Studies
(bay x 1005)
Trials
(bay x 1005)
Recent Studies (post-2010)
(bay x 1005)
Studies
(mocetinostat)
Trials
(mocetinostat)
Recent Studies (post-2010) (mocetinostat)
586821,7353908,606

Protein Interaction Comparison

ProteinTaxonomybay x 1005 (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Berti, F; Buccellati, C; Folco, GC; Maclouf, J; Molta, C; Muller-Peddinghaus, R; Rossoni, G; Sala, A; Testa, T1
Berti, F; Buccellati, C; Folco, G; Maclouf, J; Rossoni, G; Sala, A1
Adalsteinsdottir, AE; Agnarsson, U; Andersen, K; Andresdottir, M; Arnar, DO; Bjornsdottir, H; Einarsson, A; Gottskalksson, G; Gudbjartsson, D; Gudmundsdottir, H; Gudmundsson, K; Gulcher, J; Gurney, M; Hakonarson, H; Hardarson, T; Helgadottir, A; Jonsson, A; Kong, A; Kristinsson, A; Kristjansson, K; Manolescu, A; Sigurdsson, A; Stefansson, K; Thorgeirsson, G; Thorvaldsson, S; Topol, EJ; Zink, F1

Trials

1 trial(s) available for bay x 1005 and mocetinostat

ArticleYear
Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial.
    JAMA, 2005, May-11, Volume: 293, Issue:18

    Topics: 5-Lipoxygenase-Activating Proteins; Aged; Biomarkers; Carrier Proteins; Coronary Artery Disease; Cross-Over Studies; Epoxide Hydrolases; Female; Humans; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Membrane Proteins; Middle Aged; Myocardial Infarction; Peroxidase; Polymorphism, Single Nucleotide; Prospective Studies; Quinolines; Risk Factors

2005

Other Studies

3 other study(ies) available for bay x 1005 and mocetinostat

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Myocardial protection by the leukotriene synthesis inhibitor BAY X1005: importance of transcellular biosynthesis of cysteinyl-leukotrienes.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1

    Topics: Animals; Arachidonate 5-Lipoxygenase; Calcimycin; Coronary Vessels; Creatine Kinase; Cysteine; Electrocardiography; Endothelium, Vascular; Enzyme Activation; Heart; Heart Diseases; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Leukotrienes; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; Myocardium; Neutrophils; Peroxidase; Quinolines; Rabbits

1996
Leukotrienes in cardiovascular diseases.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:2 Pt 2

    Topics: Animals; Cardiovascular Diseases; Electrocardiography; Heart; In Vitro Techniques; Leukotrienes; Lipoxygenase Inhibitors; Male; Myocardium; Peroxidase; Quinolines; Rabbits; Random Allocation

2000