bay x 1005 has been researched along with ml-3000 in 4 studies
| Studies (bay x 1005) | Trials (bay x 1005) | Recent Studies (post-2010) (bay x 1005) | Studies (ml-3000) | Trials (ml-3000) | Recent Studies (post-2010) (ml-3000) |
|---|---|---|---|---|---|
| 58 | 6 | 8 | 130 | 9 | 56 |
| Protein | Taxonomy | bay x 1005 (IC50) | ml-3000 (IC50) |
|---|---|---|---|
| Prostaglandin E synthase | Homo sapiens (human) | 6.14 | |
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 0.1925 | |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 0.21 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.185 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 0.3017 | |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | 3.6 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 2.7425 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.422 | |
| 5-lipoxygenase | Bos taurus (cattle) | 0.47 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Lajeunesse, D; Laufer, S; Martel-Pelletier, J; Massicotte, F; Paredes, Y; Pelletier, JP | 1 |
| Cirino, G; Distrutti, E; Fiorucci, S; Laufor, SA; Mencarelli, A; Morelli, A; Wallace, JL | 1 |
| Cerletti, C; Evangelista, V; Krauze-Brzósko, K; Manarini, S; Rotondo, S | 1 |
4 other study(ies) available for bay x 1005 and ml-3000
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
Topics: Acetates; Alkaline Phosphatase; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Nitrobenzenes; Osteoarthritis; Osteoblasts; Osteocalcin; Pyrroles; Quinolines; Sulfonamides | 2002 |
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
Topics: Acetates; Acetylation; Adhesiveness; Arachidonate 5-Lipoxygenase; Aspirin; CD11a Antigen; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; E-Selectin; Eicosanoids; Endothelial Cells; Endothelium, Vascular; Fatty Alcohols; Glycols; Humans; Isoenzymes; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxins; Lipoxygenase; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrans; Pyrroles; Quinolines; Quinolones; Umbilical Cord; Up-Regulation | 2003 |
Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
Topics: Acetates; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epinephrine; Humans; In Vitro Techniques; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrroles; Quinolines; Thrombin; Thromboxane B2 | 2004 |