Page last updated: 2024-09-03

bay x 1005 and ml-3000

bay x 1005 has been researched along with ml-3000 in 4 studies

Compound Research Comparison

Studies
(bay x 1005)
Trials
(bay x 1005)
Recent Studies (post-2010)
(bay x 1005)
Studies
(ml-3000)
Trials
(ml-3000)
Recent Studies (post-2010) (ml-3000)
5868130956

Protein Interaction Comparison

ProteinTaxonomybay x 1005 (IC50)ml-3000 (IC50)
Prostaglandin E synthaseHomo sapiens (human)6.14
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.1925
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.21
Prostaglandin G/H synthase 1Ovis aries (sheep)0.185
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)0.3017
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)3.6
Prostaglandin G/H synthase 1Homo sapiens (human)2.7425
Prostaglandin G/H synthase 2Homo sapiens (human)0.422
5-lipoxygenase Bos taurus (cattle)0.47

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Lajeunesse, D; Laufer, S; Martel-Pelletier, J; Massicotte, F; Paredes, Y; Pelletier, JP1
Cirino, G; Distrutti, E; Fiorucci, S; Laufor, SA; Mencarelli, A; Morelli, A; Wallace, JL1
Cerletti, C; Evangelista, V; Krauze-Brzósko, K; Manarini, S; Rotondo, S1

Other Studies

4 other study(ies) available for bay x 1005 and ml-3000

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:7

    Topics: Acetates; Alkaline Phosphatase; Blotting, Western; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Nitrobenzenes; Osteoarthritis; Osteoblasts; Osteocalcin; Pyrroles; Quinolines; Sulfonamides

2002
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Acetates; Acetylation; Adhesiveness; Arachidonate 5-Lipoxygenase; Aspirin; CD11a Antigen; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; E-Selectin; Eicosanoids; Endothelial Cells; Endothelium, Vascular; Fatty Alcohols; Glycols; Humans; Isoenzymes; Leukocytes; Leukotriene B4; Lipopolysaccharides; Lipoxins; Lipoxygenase; Membrane Proteins; Neutrophils; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Pyrans; Pyrroles; Quinolines; Quinolones; Umbilical Cord; Up-Regulation

2003
Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
    European journal of pharmacology, 2004, Mar-19, Volume: 488, Issue:1-3

    Topics: Acetates; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epinephrine; Humans; In Vitro Techniques; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrroles; Quinolines; Thrombin; Thromboxane B2

2004