bay x 1005 has been researched along with l 663536 in 8 studies
| Studies (bay x 1005) | Trials (bay x 1005) | Recent Studies (post-2010) (bay x 1005) | Studies (l 663536) | Trials (l 663536) | Recent Studies (post-2010) (l 663536) |
|---|---|---|---|---|---|
| 58 | 6 | 8 | 485 | 4 | 138 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, CD; Summers, JB | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Carpenter, TG; Cuthbert, NJ; Fitzgerald, MF; Francis, HP; Gardiner, PJ; Mohrs, K; Müller-Peddinghaus, R; Newton, BB; Patel, UP; Thompson, AM | 1 |
| Dahlén, SE; Jonsson, EW | 1 |
| Brink, C; Gardiner, PJ; Gascard, JP; Gorenne, I; Labat, C; Mohrs, KH; Müller-Peddinghaus, R; Norel, X; Taylor, WA | 1 |
| Fruchtmann, R; Hatzelmann, A; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Alaoui, HS; Brink, C; De Montpreville, V; Gascard, JP; Gorenne, I; Labat, C; Norel, X | 1 |
| Folco, G; Henson, PM; Murphy, RC; Sala, A | 1 |
1 review(s) available for bay x 1005 and l 663536
| Article | Year |
|---|---|
Modulators of leukotriene biosynthesis and receptor activation.
Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Forecasting; Humans; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Membrane Proteins; Molecular Structure; Receptors, Leukotriene | 1996 |
7 other study(ies) available for bay x 1005 and l 663536
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Inhibition of antigen-induced contraction of guinea-pig airways by a leukotriene synthesis inhibitor, BAY x1005.
Topics: 5-Lipoxygenase-Activating Proteins; Administration, Oral; Animals; Benzoquinones; Bronchoconstriction; Carrier Proteins; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Indoles; Injections, Intravenous; Leukotriene Antagonists; Lipoxygenase Inhibitors; Male; Membrane Proteins; Ovalbumin; Pyrans; Quinolines; Quinolones; Trachea | 1994 |
Interactions between leukotrienes and histamine in the anaphylactic contraction of guinea pig lung parenchyma.
Topics: Anaphylaxis; Animals; Azepines; Guinea Pigs; Histamine; In Vitro Techniques; Indoles; Indomethacin; Leukotriene Antagonists; Leukotrienes; Lung; Male; Muscle Contraction; Ovalbumin; Platelet Activating Factor; Quinolines; Triazoles | 1994 |
(R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl] acetic acid (BAY x1005), a potent leukotriene synthesis inhibitor: effects on anti-IgE challenge in human airways.
Topics: Bronchi; Bronchoconstriction; Female; Humans; Immunoglobulin E; In Vitro Techniques; Indoles; Indomethacin; Leukotriene B4; Leukotriene E4; Lipoxygenase Inhibitors; Male; Quinolines | 1994 |
Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds.
Topics: Animals; Arachidonic Acid; Binding Sites; Binding, Competitive; Cell-Free System; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Quinolines; Rats; Structure-Activity Relationship; Subcellular Fractions | 1993 |
Leukotriene synthesis inhibition and anti-ige challenge of human lung parenchyma.
Topics: Humans; Immunoglobulin E; Indoles; Indomethacin; Kinetics; Leukotriene Antagonists; Leukotrienes; Lung; Protein Synthesis Inhibitors; Quinolines | 1996 |
Pharmacological modulation of human platelet leukotriene C4-synthase.
Topics: Blood Platelets; Dose-Response Relationship, Drug; Glutathione Transferase; Humans; Indoles; Lipoxygenase Inhibitors; Neutrophils; Quinolines | 1997 |