Compounds > bay x 1005

Page last updated: 2024-09-03

bay x 1005 and calcimycin

bay x 1005 has been researched along with calcimycin in 7 studies

Compound Research Comparison

Studies (bay x 1005)	Trials (bay x 1005)	Recent Studies (post-2010) (bay x 1005)	Studies (calcimycin)	Trials (calcimycin)	Recent Studies (post-2010) (calcimycin)
58	6	8	11,946	40	444

Protein Interaction Comparison

Protein	Taxonomy	bay x 1005 (IC50)	calcimycin (IC50)
XBP1	Homo sapiens (human)		1.41
DNA damage-inducible transcript 3 protein	Mus musculus (house mouse)		0.16

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Fruchtmann, R; Hatzelmann, A; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S	1
Fruchtmann, R; Fugmann, B; Hatzelmann, A; Horstmann, H; Junge, B; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S	1
Berti, F; Buccellati, C; Folco, GC; Maclouf, J; Molta, C; Muller-Peddinghaus, R; Rossoni, G; Sala, A; Testa, T	1
Andrews, M; Cunningham, FM; Landoni, MF; Lees, P	1
Fischer, AR; Israel, E; Jungerwirth, S; Loper, M; Rosenberg, MA; Roth, M	1
Bell, RL; Bhatia, P; Bouska, JB; Brooks, CD; Carter, GW; Harris, RR; Hulkower, KI; Kalosa, T; Malo, PE; Moore, J	1
Berti, F; Folco, G; Müller-Peddinghaus, R; Rossoni, G; Sala, A	1

Trials

1 trial(s) available for bay x 1005 and calcimycin

Article	Year
Effect of a novel 5-lipoxygenase activating protein inhibitor, BAYx 1005, on asthma induced by cold dry air. Thorax, 1997, Volume: 52, Issue:12 Topics: Adolescent; Adult; Analysis of Variance; Asthma; Bronchial Provocation Tests; Calcimycin; Cold Temperature; Cross-Over Studies; Double-Blind Method; Humans; Ionophores; Leukotriene B4; Lipoxygenase Inhibitors; Middle Aged; Quinolines	1997

Other Studies

6 other study(ies) available for bay x 1005 and calcimycin

Article	Year
Ca2+ ionophore A23187-stimulated secretion of azurophil granules in human polymorphonuclear leukocytes is largely mediated by endogenously formed leukotriene B4. Biochemical pharmacology, 1994, Jul-05, Volume: 48, Issue:1 Topics: Calcimycin; Cell Degranulation; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Quinolines	1994
In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis. Agents and actions, 1993, Volume: 38, Issue:3-4 Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Humans; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Methemoglobin; Mice; Mice, Inbred BALB C; Neutrophils; Quinolines; Rats; Rats, Wistar; Reactive Oxygen Species; Stereoisomerism; Xanthine Oxidase; Zymosan	1993
Myocardial protection by the leukotriene synthesis inhibitor BAY X1005: importance of transcellular biosynthesis of cysteinyl-leukotrienes. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1 Topics: Animals; Arachidonate 5-Lipoxygenase; Calcimycin; Coronary Vessels; Creatine Kinase; Cysteine; Electrocardiography; Endothelium, Vascular; Enzyme Activation; Heart; Heart Diseases; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Leukotrienes; Lipoxygenase Inhibitors; Male; Myocardial Ischemia; Myocardium; Neutrophils; Peroxidase; Quinolines; Rabbits	1996
Pharmacology of the 5-lipoxygenase inhibitors BAY Y 1015 and BAY X 1005 in the horse. Journal of veterinary pharmacology and therapeutics, 1997, Volume: 20, Issue:4 Topics: Administration, Oral; Animals; Calcimycin; Carrageenan; Cells, Cultured; Dose-Response Relationship, Drug; Eosinophils; Exudates and Transudates; Female; Horses; Injections, Intravenous; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Male; Neutrophils; Quinolines	1997
Characterization of A-93178, an iminoxy-quinoline inhibitor of leukotriene biosynthesis. Advances in experimental medicine and biology, 1997, Volume: 433 Topics: Animals; Calcimycin; Dogs; Humans; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Lipoxygenase Inhibitors; Metabolic Clearance Rate; Molecular Structure; Neutrophils; Quinolines	1997
Transcellular synthesis of Cys-LT: from isolated cells to complex organ system. Advances in experimental medicine and biology, 1997, Volume: 433 Topics: Animals; Arachidonate 5-Lipoxygenase; Calcimycin; Cardiotonic Agents; Coronary Vessels; Cysteine; Heart; Humans; In Vitro Techniques; Leukotrienes; Lipoxygenase Inhibitors; Male; Neutrophils; Perfusion; Quinolines; Rabbits; Ventricular Function, Left	1997