bay x 1005 has been researched along with arachidonic acid in 5 studies
| Studies (bay x 1005) | Trials (bay x 1005) | Recent Studies (post-2010) (bay x 1005) | Studies (arachidonic acid) | Trials (arachidonic acid) | Recent Studies (post-2010) (arachidonic acid) |
|---|---|---|---|---|---|
| 58 | 6 | 8 | 19,295 | 486 | 3,040 |
| Protein | Taxonomy | bay x 1005 (IC50) | arachidonic acid (IC50) |
|---|---|---|---|
| 60 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
| Fatty acid-binding protein, adipocyte | Homo sapiens (human) | 2.75 | |
| 10 kDa heat shock protein, mitochondrial | Homo sapiens (human) | 4.5 | |
| 60 kDa chaperonin | Escherichia coli | 7.3 | |
| 10 kDa chaperonin | Escherichia coli | 7.3 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.0715 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 0.6026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fruchtmann, R; Fugmann, B; Hatzelmann, A; Horstmann, H; Junge, B; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Fruchtmann, R; Hatzelmann, A; Mohrs, KH; Müller-Peddinghaus, R; Raddatz, S | 1 |
| Burchardt, ER; Müller-Peddinghaus, R | 2 |
| Cerletti, C; Evangelista, V; Krauze-Brzósko, K; Manarini, S; Rotondo, S | 1 |
5 other study(ies) available for bay x 1005 and arachidonic acid
| Article | Year |
|---|---|
In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis.
Topics: Animals; Arachidonic Acid; Calcimycin; Cells, Cultured; Humans; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; Macrophages, Peritoneal; Methemoglobin; Mice; Mice, Inbred BALB C; Neutrophils; Quinolines; Rats; Rats, Wistar; Reactive Oxygen Species; Stereoisomerism; Xanthine Oxidase; Zymosan | 1993 |
Mode of action of the new selective leukotriene synthesis inhibitor BAY X 1005 ((R)-2-[4-(quinolin-2-yl-methoxy)phenyl]-2-cyclopentyl acetic acid) and structurally related compounds.
Topics: Animals; Arachidonic Acid; Binding Sites; Binding, Competitive; Cell-Free System; Humans; Hydroxyeicosatetraenoic Acids; Indoles; Kinetics; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Platelet Activating Factor; Quinolines; Rats; Structure-Activity Relationship; Subcellular Fractions | 1993 |
Antiedematous effects of combination therapies with the leukotriene synthesis inhibitor BAY X 1005 in the archidonic acid-induced mouse ear inflammation test.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Disease Models, Animal; Drug Therapy, Combination; Ear; Edema; Female; Histamine H1 Antagonists; Indomethacin; Inflammation; Lipoxygenase Inhibitors; Methysergide; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrilamine; Quinolines; Serotonin Antagonists | 1997 |
Favorable combination effects of the leukotriene synthesis inhibitor BAY X 1005 and dexamethasone on edema formation in the arachidonic acid-induced mouse ear inflammation test.
Topics: Animals; Arachidonic Acid; Dexamethasone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Edema; Female; Inflammation; Lipoxygenase Inhibitors; Mice; Quinolines | 1999 |
Licofelone, an inhibitor of cyclooxygenase and 5-lipoxygenase, specifically inhibits cyclooxygenase-1-dependent platelet activation.
Topics: Acetates; Arachidonic Acid; Aspirin; Blood Platelets; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Epinephrine; Humans; In Vitro Techniques; Isoenzymes; Lipoxygenase Inhibitors; Membrane Proteins; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrroles; Quinolines; Thrombin; Thromboxane B2 | 2004 |