bay-k-8644 has been researched along with thapsigargin in 57 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 27 (47.37) | 18.2507 |
2000's | 27 (47.37) | 29.6817 |
2010's | 3 (5.26) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
Cai, W; Hao, Y; Hu, P; Ma, D; Pan, H; Xie, X; Yu, AD; Yu, J; Yuan, J; Zhang, L; Zhu, H | 1 |
Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A | 1 |
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
Gershengorn, MC; Hinkle, PM; Li, P; Sempowski, GD; Thaw, CN | 1 |
Ganitkevich, VY; Isenberg, G | 1 |
Catt, KJ; Iida, T; Krsmanovic, LZ; Mellon, PL; Merelli, F; Stojilković, SS; Zheng, L | 1 |
Christensen, SB; Mikkelsen, EO; Poulsen, SH | 1 |
Dannies, PS; Hanley, MR; Law, GJ; Pachter, JA; Thastrup, O | 1 |
Bangalore, R; Benson, T; Hinkle, PM; Kass, RS; Li, CC; Nelson, EJ | 1 |
Bonev, AD; Cheng, H; Knot, HJ; Lederer, WJ; Nelson, MT; Rubart, M; Santana, LF | 1 |
Damaj, MI; Martin, BR; Welch, SP | 1 |
Egashira, K; Fukumoto, Y; Ito, A; Kadokami, T; Shimokawa, H; Takayanagi, T; Takeshita, A | 1 |
Balla, T; Catt, KJ; Rössig, L; Zólyomi, A | 1 |
Fried, G; Liu, YA; Ostlund, E | 1 |
Giuliani, S; Maggi, CA; Santicioli, P | 1 |
Brabant, G; Mader, T; Rossig, L; Schöfl, C; von zur Mühlen, A | 1 |
Dessy, C; Godfraind, T | 1 |
Boev, KK; Petkov, GV | 1 |
Damaj, MI | 1 |
Gulati, R; Peluso, JJ | 1 |
Care, AD; Jones, GV; Morgan, G; Taylor, KR; Wooding, FB | 1 |
Helmke, RJ; Martinez, JR; Mörk, AC; Zhang, GH | 1 |
Guttmann, RP; Johnson, GV; Lesort, M; Zhang, J | 1 |
Brochiero, E; Ehrenfeld, J | 1 |
Hadziselimovic, R; Hukovic, N | 1 |
Akaike, N; Ishibashi, H; Rhee, JS | 1 |
Asano, M; Nomura, Y | 4 |
Fleischmann, BK; Gryshchenko, O; Hescheler, J; Ji, GJ; Liu, Q; Sauer, H; Viatchenko-Karpinski, S | 1 |
Böhm-Pinger, MM; Dittrich, M; Fischer, IR; Fleischmann, BK; Gryshchenko, O; Hescheler, J; Igelmund, P; Soest, J; Viatchenko-Karpinski, S | 1 |
Bansal, DD; MacGregor, RR; Puri, S; Uskoković, MR | 1 |
Harding, SE; MacLeod, KT; Tweedie, D | 1 |
Chi, DH; Storm, DS; Tostes, RC; Webb, RC | 1 |
Bartel, S; Karczewski, P; Krause, EG; Schlegel, WP; Vetter, D; Wallukat, G | 1 |
Berg Nyborg, NC; Sheykhzade, M | 1 |
Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L | 1 |
Forster, ME; Olson, KR; Packer, CS; Pelaez, NJ; Russell, MJ | 1 |
Altschuld, RA; Cheng, Y; Dumitrescu, C; Efimov, IR; Narayan, P | 1 |
Arias-Montaño, JA; García, L; Guerrero-Hernández, A; Rueda, A; Soria-Jasso, LE | 1 |
Hirasawa, M; Pittman, QJ | 1 |
Hayashi, K; Ohno, Y; Saruta, T; Suzuki, H; Takenaka, T | 1 |
Kobayashi, T; Nagashima, M; Namiki, A; Seki, S; Tohse, N; Tsutsuura, M; Yamada, Y | 1 |
Arias, E; de Los Rios, C; García, AG; León, R; López, MG; Marco, JL; Orozco, C; Villarroya, M | 1 |
Forrest, A; Molleman, A; Parsons, M | 1 |
Nakagawa, T; Yamaguchi, M | 1 |
Kato, N; Nakano, M; Udagawa, R | 1 |
Caterson, EJ; Chang, R; Hoek, JB; Li, WJ; McCann, TD; Nesti, LJ; Tuan, RS | 1 |
Nakagawa, T; Tomono, S; Yamaguchi, M | 1 |
Bendhack, LM; Rocha, ML | 1 |
Mei, HS; Qi, YJ; Su, SW; Wang, C; Wang, YL; Xu, YF; Yin, JX; Zhang, YJ | 1 |
Inoue, T; Ra, C; Suzuki, Y; Yoshimaru, T | 1 |
Arvizu, F; García, U; Gómez-Viquez, NL; Guerrero-Hernández, A; Guerrero-Serna, G | 1 |
Apfel, CM; Clerc, RG; Denelavas, A; Hertel, C; Imbach, A; Prummer, M; Weibel, F | 1 |
Aronsen, JM; Christensen, G; Hougen, K; Levy, FO; Meier, S; Moltzau, LR; Nguyen, CH; Osnes, JB; Qvigstad, E; Sjaastad, I; Skomedal, T; Ørstavik, Ø | 1 |
57 other study(ies) available for bay-k-8644 and thapsigargin
Article | Year |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; Glioblastoma; Green Fluorescent Proteins; Humans; Intracellular Membranes; Loperamide; Microtubule-Associated Proteins; Mycotoxins; Peptides; Phagosomes; Phosphatidylinositol Phosphates; Pimozide; Protein Kinases; Recombinant Fusion Proteins; Sirolimus; Small Molecule Libraries; TOR Serine-Threonine Kinases; Trifluoperazine; Zinc Fingers | 2007 |
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cell Line; DNA; Endothelins; HeLa Cells; Humans; Ion Channel Gating; Mice; Neuroglia; Nimodipine; Pituitary Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Stimulation, Chemical; Terpenes; Thapsigargin; Thyrotropin-Releasing Hormone; Transfection; Tumor Cells, Cultured | 1992 |
Contribution of Ca(2+)-induced Ca2+ release to the [Ca2+]i transients in myocytes from guinea-pig urinary bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscle, Smooth; Ryanodine; Terpenes; Thapsigargin; Time Factors; Urinary Bladder | 1992 |
Gonadotropin-releasing hormone-induced calcium signaling in clonal pituitary gonadotrophs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Dihydropyridines; Endoplasmic Reticulum; Gonadotropin-Releasing Hormone; Ionomycin; Nifedipine; Pituitary Gland; Potassium; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Comparison of the effects of thapsigargin and BAY K 8644 on spontaneous mechanical activity in rat portal vein and contractile responses of rat cardiac muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Histamine Release; In Vitro Techniques; Male; Myocardial Contraction; Plant Extracts; Plants, Medicinal; Portal Vein; Rats; Rats, Inbred Strains; Terpenes; Thapsigargin | 1992 |
Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Cell Line; Inositol Phosphates; Kinetics; Nimodipine; Pituitary Neoplasms; Plants, Medicinal; Prolactin; Terpenes; Thapsigargin; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1990 |
Inhibition of L-type calcium-channel activity by thapsigargin and 2,5-t-butylhydroquinone, but not by cyclopiazonic acid.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Hydroquinones; Indoles; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Potassium; Rats; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1994 |
Relaxation of arterial smooth muscle by calcium sparks.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channels; Cell Membrane; Cerebral Arteries; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Peptides; Potassium Channels; Rats; Ryanodine; Sarcoplasmic Reticulum; Terpenes; Thapsigargin; Vasodilation | 1995 |
Involvement of calcium and L-type channels in nicotine-induced antinociception.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesia; Animals; Behavior, Animal; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels; Injections, Spinal; Intracellular Fluid; Kinetics; Male; Mecamylamine; Mice; Mice, Inbred ICR; Nicotine; Nitrendipine; Nociceptors; Pain Measurement; Rats; Receptors, Nicotinic; Terpenes; Thapsigargin; Tritium | 1993 |
Coronary artery spasm does not depend on the intracellular calcium store but is substantially mediated by the protein kinase C-mediated pathway in a swine model with interleukin-1 beta in vivo.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Coronary Vasospasm; Cytosol; Enzyme Activation; Histamine; Interleukin-1; Male; Muscle, Smooth, Vascular; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Serotonin; Sphingosine; Staurosporine; Swine; Terpenes; Thapsigargin | 1996 |
Regulation of angiotensin II-stimulated Ca2+ oscillations by Ca2+ influx mechanisms in adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium; Calcium Channels; Cattle; Dihydropyridines; Dose-Response Relationship, Drug; Evoked Potentials; Inositol Phosphates; Nifedipine; Terpenes; Thapsigargin; Zona Glomerulosa | 1996 |
Endothelin-induced contractions in human placental blood vessels are enhanced in intrauterine growth retardation, and modulated by agents that regulate levels of intracellular calcium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Arteries; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Endothelins; Enzyme Inhibitors; Female; Fetal Growth Retardation; Humans; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Placental Circulation; Pregnancy; Ryanodine; Terpenes; Thapsigargin | 1995 |
CGRP inhibition of electromechanical coupling in the guinea-pig isolated renal pelvis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Arginine; Calcitonin Gene-Related Peptide; Calcium; Carbazoles; Enzyme Inhibitors; Glyburide; Guinea Pigs; In Vitro Techniques; Indoles; Isoquinolines; Kidney Pelvis; Male; Membrane Potentials; Nitroarginine; Potassium Channels; Ryanodine; Sucrose; Sulfonamides; Terpenes; Tetrodotoxin; Thapsigargin | 1995 |
CYCLIC adenosine 3',5'-monophosphate potentiates Ca2+ signaling and insulin secretion by phospholipase C-linked hormones in HIT cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Arginine Vasopressin; Bombesin; Calcium; Calcium-Transporting ATPases; Cell Line; Colforsin; Cricetinae; Cyclic AMP; Egtazic Acid; Enzyme Inhibitors; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Mesocricetus; Nifedipine; Signal Transduction; Terpenes; Thapsigargin; Time Factors | 1996 |
The effect of L-type calcium channel modulators on the mobilization of intracellular calcium stores in guinea-pig intestinal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Diazoxide; Fura-2; Guinea Pigs; Histamine; Ileum; Isometric Contraction; Muscle, Smooth; Nimodipine; Ryanodine; Thapsigargin | 1996 |
The role of sarcoplasmic reticulum and sarcoplasmic reticulum Ca2+-ATPase in the smooth muscle tone of the cat gastric fundus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apamin; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Cats; Cinnarizine; Enzyme Inhibitors; Gastric Fundus; In Vitro Techniques; Indoles; Male; Molsidomine; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitroprusside; Potassium Channel Blockers; Sarcoplasmic Reticulum; Thapsigargin | 1996 |
Altered behavioral sensitivity of Ca(2+)-modulating drugs after chronic nicotine administration in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Behavior, Animal; Binding Sites; Brain; Calcium; Calcium Channels; Drug Tolerance; Ion Transport; Male; Mice; Mice, Inbred ICR; Motor Activity; Nicotine; Nitrendipine; Thapsigargin; Tritium | 1997 |
Opposing actions of hepatocyte growth factor and basic fibroblast growth factor on cell contact, intracellular free calcium levels, and rat ovarian surface epithelial cell viability.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3T3 Cells; Animals; Apoptosis; Calcium; Cell Adhesion; Cell Division; Cell Line; Cycloheximide; Dactinomycin; Egtazic Acid; Epithelial Cells; Female; Fibroblast Growth Factor 2; Hepatocyte Growth Factor; Kinetics; Mice; Ovary; Rats; Thapsigargin | 1997 |
Aspects of calcium transport by the ovine placenta: studies based on the interplacentomal region of the chorion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcimycin; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Chorion; Female; Gestational Age; Ionophores; Kinetics; Lanthanum; Nickel; Placenta; Pregnancy; Sheep; Temperature; Thapsigargin | 1997 |
Regulation of cytosolic free Ca2+ in cultured rat alveolar macrophages (NR8383).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Cytosol; Enzyme Inhibitors; Imidazoles; Inositol 1,4,5-Trisphosphate; Macrophages, Alveolar; Membrane Potentials; Rats; Receptors, Purinergic P2; Thapsigargin; Zymosan | 1997 |
Modulation of the in situ activity of tissue transglutaminase by calcium and GTP.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Antineoplastic Agents; Calcium; Calcium Channel Agonists; Calpain; Carbachol; Diazomethane; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Ionomycin; Ionophores; Marine Toxins; Muscarinic Agonists; Oligopeptides; Oxocins; Receptors, Retinoic Acid; Retinoid X Receptors; Ribavirin; Thapsigargin; Transcription Factors; Transglutaminases; Tumor Cells, Cultured | 1998 |
Characterisation of Ca2+ membrane permeability of renal A6 cells upon different osmotic conditions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Bacterial Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Enzyme Inhibitors; Gallic Acid; Gramicidin; Intracellular Fluid; Ion Transport; Kidney Tubules, Distal; Membrane Potentials; Osmolar Concentration; Thapsigargin; Xenopus laevis | 1997 |
Endothelin 1 action on isolated rat stomach and the role of calcium ions in ET 1 induced depolarization of smooth muscle cells BC3H1.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic Antagonists; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cell Line; Cholinergic Antagonists; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Membrane Potentials; Mice; Muscle Contraction; Muscle, Smooth; Nitrendipine; omega-Conotoxin GVIA; Peptides; Serotonin Antagonists; Stomach; Thapsigargin | 1998 |
Calcium channels in the GABAergic presynaptic nerve terminals projecting to meynert neurons of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cholinergic Fibers; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Nicardipine; omega-Conotoxin GVIA; omega-Conotoxins; Organ Culture Techniques; Peptides; Presynaptic Terminals; Rats; Rats, Wistar; Ryanodine; Substantia Innominata; Tetrodotoxin; Thapsigargin | 1999 |
Ca2+ buffering action of sarcoplasmic reticulum on Bay k 8644-induced Ca2+ influx in rat femoral arterial smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Enzyme Inhibitors; Femoral Artery; In Vitro Techniques; Indoles; Mice; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Potassium; Rats; Rats, Inbred WKY; Ryanodine; Sarcoplasmic Reticulum; Thapsigargin | 1999 |
Intracellular Ca2+ oscillations drive spontaneous contractions in cardiomyocytes during early development.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Differentiation; Cell Line; Cells, Cultured; Kinetics; Microscopy, Confocal; Myocardial Contraction; Myocardium; Nickel; Nisoldipine; Oscillometry; Potassium; Stem Cells; Thapsigargin | 1999 |
Role of ATP-dependent K(+) channels in the electrical excitability of early embryonic stem cell-derived cardiomyocytes.
Topics: 2,4-Dinitrophenol; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Calcium Channel Agonists; Cardiotonic Agents; Cell Differentiation; Charybdotoxin; Cromakalim; Enzyme Inhibitors; Glyburide; Isoproterenol; KATP Channels; Membrane Potentials; Mice; Myocardial Contraction; Myocardium; Organoids; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Stem Cells; Thapsigargin | 1999 |
Induction of tissue plasminogen activator secretion from rat heart microvascular cells by fM 1,25(OH)(2)D(3).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitriol; Calcium; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; Coronary Vessels; Female; Humans; Isoproterenol; Microcirculation; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Thapsigargin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 2000 |
Sarcoplasmic reticulum Ca content, sarcolemmal Ca influx and the genesis of arrhythmias in isolated guinea-pig cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Cells, Cultured; Enzyme Inhibitors; Guinea Pigs; Heart; Ion Transport; Isoproterenol; Membrane Potentials; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Thapsigargin | 2000 |
Intracellular calcium stores and oscillatory contractions in arteries from genetically hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Blood Pressure; Calcimycin; Calcium; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Calcium-Transporting ATPases; Carbamates; Enzyme Inhibitors; Female; Hypertension; Indoles; Inositol 1,4,5-Trisphosphate Receptors; Ionophores; Male; Muscle, Smooth, Vascular; Periodicity; Phenylcarbamates; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; Ryanodine; Sarcoplasmic Reticulum; Tail; Tetraethylammonium; Thapsigargin; Type C Phospholipases; Vasoconstriction | 1996 |
Phosphorylation of phospholamban at threonine-17 in the absence and presence of beta-adrenergic stimulation in neonatal rat cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ionophores; Isoproterenol; Myocardium; Okadaic Acid; Phosphorylation; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Serine; Signal Transduction; Thapsigargin; Threonine; Time Factors | 2000 |
Mechanism of CGRP-induced relaxation in rat intramural coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Calcitonin Gene-Related Peptide; Calcium; Calcium Channel Agonists; Charybdotoxin; Coronary Vessels; Drug Interactions; Enzyme Inhibitors; Felodipine; Fluorescent Dyes; Fura-2; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Male; Osmolar Concentration; Peptides; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Rest; Thapsigargin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil | 2001 |
Calcium buffering of resting, voltage-dependent Ca2+ influx by sarcoplasmic reticulum in femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Radioisotopes; Calcium-Transporting ATPases; Enzyme Inhibitors; Femoral Artery; Hypertension; Indoles; Male; Muscle Contraction; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Verapamil | 2001 |
Intracellular and extracellular calcium utilization during hypoxic vasoconstriction of cyclostome aortas.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Enzyme Inhibitors; Gallopamil; Hagfishes; Hypoxia; In Vitro Techniques; Indoles; Ionomycin; Ionophores; Lampreys; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Ryanodine; Thapsigargin; Vasoconstriction; Vasodilator Agents | 2001 |
Phase I and phase II of short-term mechanical restitution in perfused rat left ventricles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Benzylamines; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Perfusion; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Sulfonamides; Systole; Thapsigargin; Time Factors; Vasodilation; Ventricular Function, Left | 2002 |
The initial inositol 1,4,5-trisphosphate response induced by histamine is strongly amplified by Ca(2+) release from internal stores in smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Androstadienes; Animals; Calcium; Carbachol; Cimetidine; Extracellular Space; Guinea Pigs; Histamine; Histamine Agonists; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium; Muscle, Smooth; Pyrilamine; Ryanodine; Thapsigargin; Type C Phospholipases; Urinary Bladder; Wortmannin | 2002 |
Ca2+ buffering function of the sarcoplasmic reticulum is increased in the carotid artery from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Buffers; Caffeine; Calcium; Calcium Channel Agonists; Carotid Arteries; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Indoles; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcoplasmic Reticulum; Thapsigargin; Vasoconstriction | 2002 |
Increased Ca2+ buffering function of sarcoplasmic reticulum in small mesenteric arteries from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Animals; Buffers; Calcium; Calcium Channel Agonists; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Indoles; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine; Sarcoplasmic Reticulum; Thapsigargin; Vasoconstriction | 2002 |
Nifedipine facilitates neurotransmitter release independently of calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Cadmium; Calcium Channel Blockers; Calcium Channels, L-Type; Egtazic Acid; In Vitro Techniques; Kinetics; Male; Neurotransmitter Agents; Nifedipine; Quinoxalines; Rats; Rats, Sprague-Dawley; Thapsigargin | 2003 |
Governance of arteriolar oscillation by ryanodine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Boron Compounds; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Enzyme Inhibitors; Hydronephrosis; Kidney Glomerulus; Male; Nifedipine; Ouabain; Periodicity; Phosphodiesterase Inhibitors; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Renal Circulation; Ryanodine; Ryanodine Receptor Calcium Release Channel; Tetraethylammonium; Thapsigargin; Vasoconstriction | 2003 |
Fetal and postnatal development of Ca2+ transients and Ca2+ sparks in rat cardiomyocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Calcium; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Electrophysiology; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Heart; Heart Conduction System; Humans; Microscopy, Confocal; Microscopy, Fluorescence; Myocytes, Cardiac; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Thapsigargin | 2003 |
ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a novel acetylcholinesterase inhibitor with "calcium promotor" and neuroprotective properties.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amyloid beta-Peptides; Animals; Calcium; Cattle; Cholinesterase Inhibitors; Chromaffin Cells; Cytoprotection; Drug Combinations; Drug Interactions; Free Radicals; Humans; Neuroblastoma; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Tacrine; Thapsigargin; Tumor Cells, Cultured; Veratridine | 2004 |
The responses to manipulation of extracellular and intracellular calcium are altered in the streptozotocin-diabetic rat colon and ileum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Chloride; Calcium Signaling; Calcium-Transporting ATPases; Colon, Ascending; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Ileum; Indoles; Injections, Intraperitoneal; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Rats, Wistar; Streptozocin; Thapsigargin; Time Factors | 2005 |
Overexpression of regucalcin suppresses apoptotic cell death in cloned normal rat kidney proximal tubular epithelial NRK52E cells: change in apoptosis-related gene expression.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apoptosis; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cell Line, Tumor; Clone Cells; DNA Fragmentation; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Intracellular Signaling Peptides and Proteins; Kidney Tubules, Proximal; Lipopolysaccharides; Rats; Sulfotransferases; Thapsigargin; Transfection; Tumor Necrosis Factor-alpha | 2005 |
Blocking L-type calcium channels enhances long-term depression induced by low-frequency stimulation at hippocampal CA1 synapses.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Radiation; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Male; Neurons; Nifedipine; Patch-Clamp Techniques; Rats; Rats, Wistar; Synapses; Thapsigargin; Valine | 2006 |
TGF-beta1 calcium signaling in osteoblasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Cell Adhesion; Cells, Cultured; Enzyme Inhibitors; Humans; Nifedipine; Osteoblasts; Thapsigargin; Transforming Growth Factor beta1 | 2007 |
Overexpression of RGPR-p117 suppresses apoptotic cell death and its related gene expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspase Inhibitors; Cell Count; Cell Line; Clone Cells; DNA Fragmentation; DNA-Binding Proteins; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Gene Expression Regulation; Kidney Tubules, Proximal; Lipopolysaccharides; Rats; Thapsigargin; Tumor Necrosis Factor-alpha | 2007 |
Aortas isolated from sinoaortic-denervated rats exhibit rhythmic contractions that are regulated by pharmacologically distinct calcium sources.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Aorta, Thoracic; Autonomic Denervation; Blood Pressure; Boron Compounds; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Chloride Channels; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate Receptors; Male; Membrane Transport Modulators; Nitrobenzoates; Periodicity; Phenylephrine; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sodium Channel Blockers; Sodium-Calcium Exchanger; Thapsigargin; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Verapamil | 2008 |
Effects of strophanthidin on intracellular calcium concentration in ventricular myocytes of guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aequorin; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Fura-2; Guinea Pigs; Myocardium; Nifedipine; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Strophanthidin; Tetrodotoxin; Thapsigargin | 2008 |
Ca v 1.2 L-type Ca2+ channel protects mast cells against activation-induced cell death by preventing mitochondrial integrity disruption.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apoptosis; Bone Marrow Cells; Calcium Channels, L-Type; Calcium Signaling; Cell Line; Cell Survival; Ion Channel Gating; Mast Cells; Membrane Potential, Mitochondrial; Mice; Mitochondria; Nifedipine; Protein Subunits; Receptors, IgE; Thapsigargin | 2009 |
Inhibition of SERCA pumps induces desynchronized RyR activation in overloaded internal Ca2+ stores in smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Agonists; Enzyme Inhibitors; Gene Expression Regulation; Guinea Pigs; Myocytes, Smooth Muscle; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin | 2010 |
Real-time cellular impedance measurements detect Ca(2+) channel-dependent oscillations of morphology in human H295R adrenoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Cortex; Angiotensin II; Calcium; Calcium Channels, L-Type; Calmodulin; Cell Line; Cell Shape; Electric Impedance; Heterocyclic Compounds, 4 or More Rings; Humans; Imaging, Three-Dimensional; Intracellular Space; Ouabain; RNA, Small Interfering; Thapsigargin; Time Factors | 2011 |
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium-Binding Proteins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Heart Failure; Isoproterenol; Male; Mice; Mice, Knockout; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, C-Type; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thionucleotides; Troponin I | 2013 |