bay-k-8644 and phorbol 12,13-dibutyrate

bay-k-8644 has been researched along with phorbol 12,13-dibutyrate in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's13 (59.09)18.2507
2000's4 (18.18)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balfagón, G; de Sagarra, MR; Encabo, A; Ferrer, M; Marín, J; Peiró, C; Redondo, J1
Glembotski, CC; Hidaka, H; Irons, CE; Sei, CA1
Crevel, H; Marthan, R; Savineau, JP1
Endoh, M; Takanashi, M1
Litten, RZ; Roth, BL; Suba, EA1
Dale, MM; Hirst, SJ; Obianime, AW1
Hai, CM; Murphy, RA; Ratz, PH1
Prives, J; Rapuano, M; Ross, AF1
Glembotski, CC; McDonough, PM; Stella, SL1
Egashira, K; Fukai, T; Ito, A; Nakaike, R; Sakata, M; Shimokawa, H; Takayanagi, T; Takeshita, A1
Haist, JV; Karmazyn, M1
Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ1
Egashira, K; Fukumoto, Y; Ito, A; Kadokami, T; Shimokawa, H; Takayanagi, T; Takeshita, A1
YaDeau, JT1
Bevan, JA; Laher, I; Xie, H1
Brady, G; Docherty, JR1
Kawasaki, H1
Coats, P; Hillier, C; Johnston, F; MacDonald, J; McMurray, JJ1
Koizumi, N; Masui, H; Siogawa, K; Wakabayashi, I1
Fukuhara, S; Inagaki, C; Oshiro, A; Otani, H; Yagi, Y1
Bollag, WB; Calle, RA; Isales, CM; Kent, P; Malinova, M; White, S1
Cardoso-Teixeira, AC; Coelho-de-Souza, AN; Ferreira-da-Silva, FW; Leal-Cardoso, JH; Oliveira-Abreu, K; Peixoto-Neves, D; Pereira-Gonçalves, Á1

Other Studies

22 other study(ies) available for bay-k-8644 and phorbol 12,13-dibutyrate

ArticleYear
Comparison of the vasoconstrictor responses induced by endothelin and phorbol 12,13-dibutyrate in bovine cerebral arteries.
    Brain research, 1992, Dec-25, Volume: 599, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cattle; Cerebral Arteries; Cytosol; Electric Stimulation; Endothelins; Enzyme Activation; Membranes; Nifedipine; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Serotonin; Vasoconstriction

1992
Protein kinase C and calmodulin kinase are required for endothelin-stimulated atrial natriuretic factor secretion from primary atrial myocytes.
    The Journal of biological chemistry, 1992, Mar-15, Volume: 267, Issue:8

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Natriuretic Factor; Cells, Cultured; Endothelins; Heart; Heart Atria; Isoquinolines; Kinetics; Myocardium; Nifedipine; Phorbol 12,13-Dibutyrate; Phosphorylation; Piperazines; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Sulfonamides

1992
Contraction of vascular smooth muscle induced by phorbol 12,13 dibutyrate in human and rat pulmonary arteries.
    British journal of pharmacology, 1991, Volume: 104, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Calcium; Humans; In Vitro Techniques; Isometric Contraction; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Phentolamine; Phorbol 12,13-Dibutyrate; Potassium; Propranolol; Protein Kinase C; Pulmonary Artery; Rats; Tetrodotoxin; Trifluoperazine; Verapamil

1991
Differential inhibitory action of phorbol-12,13-dibutyrate on the positive inotropic effect of endothelin-1 and Bay K 8644 in the isolated rabbit papillary muscle.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 7

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Electric Stimulation; Endothelins; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Phorbol 12,13-Dibutyrate; Rabbits; Signal Transduction; Stimulation, Chemical

1991
Effects of a phorbol ester on rat aortic contraction and calcium influx in the presence and absence of BAY k 8644.
    European journal of pharmacology, 1987, Dec-01, Volume: 144, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channel Agonists; Drug Interactions; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats

1987
Interactions between phorbol esters and agents which increase cytosolic calcium in the guinea pig parenchymal strip: direct and indirect effects on the contractile response.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Cytosol; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Lung; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Tetradecanoylphorbol Acetate; Vanadates

1988
Dependence of stress on cross-bridge phosphorylation in vascular smooth muscle.
    The American journal of physiology, 1989, Volume: 256, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Ethers; Histamine; Ionomycin; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myosins; Phorbol 12,13-Dibutyrate; Phosphoproteins; Potassium; Swine

1989
Opposing effects of calcium entry and phorbol esters on fusion of chick muscle cells.
    Developmental biology, 1989, Volume: 134, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Blockers; Cell Fusion; Cells, Cultured; Chick Embryo; Egtazic Acid; Gallopamil; Kinetics; Muscles; Myosin Subfragments; Myosin-Light-Chain Kinase; Myosins; Nitrendipine; Peptide Fragments; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Tetradecanoylphorbol Acetate

1989
Involvement of cytoplasmic calcium and protein kinases in the regulation of atrial natriuretic factor secretion by contraction rate and endothelin.
    The Journal of biological chemistry, 1994, Apr-01, Volume: 269, Issue:13

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Analysis of Variance; Animals; Animals, Newborn; Atrial Natriuretic Factor; Benzophenanthridines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cytoplasm; Endothelins; Fluorescent Dyes; Heart; Heart Atria; Indoles; Isoquinolines; Kinetics; Myocardial Contraction; Myocardium; Phenanthridines; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Phosphoproteins; Piperazines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence

1994
Role of protein kinase C-mediated pathway in the pathogenesis of coronary artery spasm in a swine model.
    Circulation, 1994, Volume: 90, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Coronary Vasospasm; Disease Models, Animal; Histamine; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Serotonin; Staurosporine; Swine; Swine, Miniature

1994
Calcium dependent positive inotropic effects of low phorbol ester concentrations in isolated rat hearts.
    Cardiovascular research, 1993, Volume: 27, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Chloride; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabolism; Male; Myocardial Contraction; Myocardium; Phorbol 12,13-Dibutyrate; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors

1993
The involvement of dihydropyridine-sensitive calcium channels in phorbol ester-induced luteinizing hormone and growth hormone release.
    Molecular and cellular endocrinology, 1993, Volume: 95, Issue:1-2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Calcium Channels; Dihydropyridines; Female; Growth Hormone; Ion Channel Gating; Isoquinolines; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

1993
Coronary artery spasm does not depend on the intracellular calcium store but is substantially mediated by the protein kinase C-mediated pathway in a swine model with interleukin-1 beta in vivo.
    Circulation, 1996, Jul-15, Volume: 94, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium-Transporting ATPases; Coronary Vasospasm; Cytosol; Enzyme Activation; Histamine; Interleukin-1; Male; Muscle, Smooth, Vascular; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Ryanodine; Sarcoplasmic Reticulum; Serotonin; Sphingosine; Staurosporine; Swine; Terpenes; Thapsigargin

1996
Inhibition of regulated neuropeptide secretion from mouse pituitary cells by propofol.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Anesthetics, Intravenous; Animals; Barium Compounds; beta-Endorphin; Calcium Channel Agonists; Cell Line; Chlorides; Immunoassay; Mice; Phorbol 12,13-Dibutyrate; Pituitary Gland; Propofol

1996
Protein kinase C modulates flow-initiated contraction.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Male; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Regional Blood Flow; Staurosporine; Tetradecanoylphorbol Acetate; Vasoconstriction

1996
Prejunctional actions of K+ channel blockers in rat vas deferens.
    European journal of pharmacology, 1995, Dec-20, Volume: 287, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Adenosine Triphosphate; Anesthetics; Animals; Apamin; Calcium; Charybdotoxin; Electric Stimulation; Enzyme Activation; Isometric Contraction; Male; Neuromuscular Junction; Norepinephrine; Phorbol 12,13-Dibutyrate; Potassium Channel Blockers; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Structure-Activity Relationship; Tetraethylammonium; Tetraethylammonium Compounds; Vas Deferens; Xylazine

1995
[Pharmacological studies on alterations in contractile reactivity in aortas isolated from experimental diabetic rats].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1997, Volume: 72, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Nifedipine; Norepinephrine; Phorbol 12,13-Dibutyrate; Potassium; Protein Kinase C; Rats; Rats, Wistar; Serotonin; Staurosporine; Streptozocin; Vasoconstriction; Vasoconstrictor Agents

1997
Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries.
    Cardiovascular research, 2001, Volume: 49, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aged; Analysis of Variance; Arteries; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cyclohexanones; Enzyme Inhibitors; Estrenes; Female; Humans; In Vitro Techniques; Indoles; Lipoprotein Lipase; Male; Middle Aged; Muscle, Smooth, Vascular; Naphthalenes; Nifedipine; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrrolidinones; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Type C Phospholipases; Vascular Resistance

2001
Diminished inibitory action of ethanol on the contraction of gallbladder isolated from chronically ethanol-fed Guinea pigs.
    Pharmacology, 2002, Volume: 65, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Body Weight; Calcium Channel Agonists; Dose-Response Relationship, Drug; Ethanol; Gallbladder; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Phorbol 12,13-Dibutyrate; Potassium Chloride; Verapamil

2002
Protease-activated receptor-2-mediated inhibition for Ca2+ response to lipopolysaccharide in Guinea pig tracheal epithelial cells.
    American journal of respiratory cell and molecular biology, 2004, Volume: 30, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Guinea Pigs; Isoenzymes; Lipopolysaccharides; Okadaic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptor, PAR-2; Respiratory Mucosa; Trachea; Trypsin

2004
Characterization and phospholipase D mediation of the angiotensin II priming response in adrenal glomerulosa cells.
    Endocrinology, 2007, Volume: 148, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Agonists; Cattle; Cells, Cultured; Diglycerides; Enzyme Activation; Extracellular Fluid; Phorbol 12,13-Dibutyrate; Phospholipase D; Signal Transduction; Time Factors; Zona Glomerulosa

2007
Hydroxyl Group and Vasorelaxant Effects of Perillyl Alcohol, Carveol, Limonene on Aorta Smooth Muscle of Rats.
    Molecules (Basel, Switzerland), 2018, Jun-13, Volume: 23, Issue:6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Cyclohexane Monoterpenes; Cyclohexenes; Isometric Contraction; Limonene; Molecular Structure; Monoterpenes; Muscle, Smooth, Vascular; Phenylephrine; Phorbol 12,13-Dibutyrate; Rats; Structure-Activity Relationship; Terpenes; Vasodilator Agents

2018