bay-k-8644 has been researched along with nimodipine in 134 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (22.39) | 18.7374 |
| 1990's | 77 (57.46) | 18.2507 |
| 2000's | 22 (16.42) | 29.6817 |
| 2010's | 5 (3.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; Jiang, JL; Melman, N; Olah, ME; Stiles, GL; van Rhee, AM | 1 |
| Baraldi, PG; Geppetti, P; Materazzi, S; Preti, D | 1 |
| Lipscombe, D; Xu, W | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Gershengorn, MC; Hinkle, PM; Li, P; Sempowski, GD; Thaw, CN | 1 |
| Hinkle, PM; Nelson, EJ; Shanshala, ED | 1 |
| De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR | 1 |
| Douglas, WW; Nemeth, EF; Taraskevich, PS | 1 |
| Dierssen, M; Flórez, J; Hurlé, MA | 2 |
| Battaini, F; Di Giovine, S; Goss, I; Govoni, S; Trabucchi, M | 1 |
| Little, HJ; Littleton, JM; Whittington, MA | 1 |
| Abele, AE; Miller, RJ; Scholz, KP; Scholz, WK | 1 |
| Cuccaro, ML; Jacobs, LS; Lorenson, MY | 1 |
| Dannies, PS; Hanley, MR; Law, GJ; Pachter, JA; Thastrup, O | 1 |
| Kunert-Radek, J; Lyson, K; Pawlikowski, M; Stepien, H | 1 |
| Carpentier, RG; Isaacson, RL; Salvatici, RP | 1 |
| Boonen, HC; De Mey, JG | 1 |
| Hayden, HC; Herbette, LG; Mason, RP; Moring, J; Salomon, RM; Shoemaker, WJ; Skita, V | 1 |
| Bolger, GT; O'Neill, SK | 1 |
| Audinot, V; Bockaert, J; Enjalbert, A; Guillon, G; Kordon, C; Mouillac, B; Rasolonjanahary, R | 1 |
| Carpentier, RG; Gallardo-Carpentier, A; Isaacson, RL; Salvatici, RP | 1 |
| Kocsis, JD; O'Regan, MH; Waxman, SG | 1 |
| Horváth, E; Traber, J; Warmuth, I; Zilles, Z | 1 |
| Kunze, DL; Ritchie, AK | 1 |
| Day, RN; Maurer, RA | 1 |
| Callahan, PM; Cunningham, KA | 2 |
| Deyo, RA; Disterhoft, JF; Thompson, LT | 1 |
| Ramsdell, JS | 1 |
| Crill, WE; Sayer, RJ; Schwindt, PC | 1 |
| Fox, AP; Scroggs, RS | 1 |
| Regan, LJ | 1 |
| Dierssen, M; Flórez, J; Hurlé, MA; Ruiz, F | 2 |
| Dannies, PS; Law, GJ; Pachter, JA | 1 |
| Dutar, P; Lamour, Y; Potier, B; Rascol, O | 1 |
| Cao, CQ; Zhu, LX | 1 |
| Abraham, WC; Wickens, JR | 1 |
| Nelson, MT; Quayle, JM; Standen, NB; Worley, JF | 1 |
| Claeson, P; Högestätt, ED; Zygmunt, P | 1 |
| Bellemann, P; Franckowiak, G | 1 |
| Hess, P; Reeves, JP; Rosenberg, RL; Smilowitz, H; Tsien, RW | 1 |
| Leslie, SW; Woodward, JJ | 1 |
| Bradford, HF; White, EJ | 1 |
| Traber, J; Van Rooijen, LA | 1 |
| Artalejo, CR; Garcia, AG | 1 |
| Bevan, JA; Hwa, JJ | 1 |
| Brown, DA; Docherty, RJ | 2 |
| Pillai, NP; Ross, DH | 1 |
| Douglas, WW; Taraskevich, PS | 1 |
| Enyeart, JJ; Hinkle, PM; Sheu, SS | 1 |
| Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A | 1 |
| Carlsson, A; Pileblad, E | 1 |
| Atchison, WD; O'Leary, SM | 1 |
| Skattebøl, A; Triggle, DJ | 1 |
| Bacciottini, L; Carlà, V; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Dolin, SJ; Halsey, MJ; Hunter, AB; Little, HJ | 1 |
| Childs, GV; Unabia, G | 1 |
| Andersson, KE; Arner, M; Högestätt, ED | 1 |
| Childs, M; Laurent, S; Martin, P; Massol, J; Puech, AJ | 1 |
| Hinkle, PM; Shanshala, ED | 1 |
| Huang, LY | 1 |
| Carpentier, RG; Carryl, OR; Isaacson, RL; Salvatici, PP | 1 |
| Bellemann, P | 2 |
| Enyeart, JJ; Hinkle, PM | 1 |
| Kojima, I; Kojima, K; Rasmussen, H | 1 |
| Grupp, G; Grupp, IL; Schwartz, A; Vaghy, PL; Williams, JS | 1 |
| de la Fuente, M; Fonteríz, RI; Gandía, L; García, AG; García-Sancho, J; López, MG; Villarroya, M | 1 |
| Hinkle, PM; Osborne, ME | 1 |
| Dusseau, J; Hutchins, PM | 1 |
| Abraham, WC; Christie, BR | 1 |
| Annunziato, L; Bassi, A; Caso, N; Di Renzo, G; Fatatis, A; Iannotti, E; Mita, GD | 1 |
| Kuzmin, AV; Patkina, NA; Zvartau, EE | 1 |
| Ates, N; Coenen, AM; van Luijtelaar, EL | 1 |
| Filloux, FM; Fitts, RC; Skeen, GA; White, HS | 1 |
| Badia, A; Clos, MV; Garcia Sanz, A; Pastor, C; Sabriá, J | 1 |
| Amico, C; Marchetti, C; Nobile, M; Usai, C | 1 |
| Arneric, SP; Donnelly-Roberts, DL; Sullivan, JP | 1 |
| Kinard, TA; Satin, LS; Tavalin, SJ; Teague, J | 1 |
| Bean, BP; Boland, LM | 1 |
| Martinez-Piñero, MG; Milanés, MV; Vargas, ML | 1 |
| Alfaro, MJ; Colado, MI; Del Val, V; Lopez, F; Martin, MI | 1 |
| Szabó, C; Thiemermann, C; Vane, JR | 1 |
| Hume, RI; Lin, X; Nuttall, AL | 1 |
| Kamishima, T; McCarron, JG | 1 |
| Löscher, W; Richter, A | 1 |
| Garaulet, JV; Laorden, ML; Milanés, MV | 2 |
| Hinkle, PM; Shupnik, MA; Weck, J | 1 |
| Bobbin, RP; Fallon, M; Kujawa, SG; Skellett, RA | 1 |
| Dessy, C; Godfraind, T | 1 |
| de Beun, R; De Vry, J; Klein, A; Lohmann, A; Schneider, R; Schreiber, R | 1 |
| Kuzmin, A; Ramsey, NF; Semenova, S; Van Ree, JM; Zvartau, EE | 1 |
| Chang, X; Javors, MA; King, TS; Klein, NA; Schenken, RS | 1 |
| Nebe, J; Neugebauer, V; Rümenapp, P; Schaible, HG; Vanegas, H | 1 |
| Huang, CS; Nagata, K; Narahashi, T; Song, JH; Yeh, JZ | 1 |
| Cohen, C; Perrault, G; Sanger, DJ | 1 |
| Brosenitsch, TA; Katz, DM; Kunze, DL; Salgado-Commissariat, D | 1 |
| Imoto, K; Mori, Y; Niidome, T; Strobeck, M; Teramoto, T; Wakamori, M | 1 |
| Gollasch, M; Haase, H; Haller, H; Lindschau, C; Luft, FC; Morano, I; Ried, C | 1 |
| Foehring, RC; Pineda, JC; Waters, RS | 1 |
| Brust, PF; Hans, M; Harpold, MM; Prodanovich, P; Stauderman, KA; Urrutia, A; Washburn, MS; Williams, ME | 1 |
| Clay, CM; Duval, DL; Mulvaney, JM; Roberson, MS; White, BR | 1 |
| Chen, CC; Li, JM; Ning, K; Wang, ZG; Zhu, PF | 1 |
| Cannon, SC; Morrill, JA | 1 |
| Lyons, HJ; Lyons, LF; Taraskevich, PS | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Pan, ZH | 1 |
| Arias-Montaño, JA; Cota, G; Lopez-Santiago, LF; Monjaraz, E; Navarrete, A; Vega, AV | 1 |
| Grant, KA; Green-Jordan, K | 1 |
| Elants, C; Scheenen, W; van Luijtelaar, G; Wiaderna, D | 1 |
| Elmslie, KS; Liang, H | 1 |
| Paki, B; Robertson, D | 1 |
| Atchison, WD; Hajela, RK; Peng, S | 1 |
| Nedergaard, OA; Uhrenholt, TR | 1 |
| Habermann, CJ; O'Brien, BJ; Protti, DA; Wässle, H | 1 |
| Cota, G; Espinosa, JL; López-Domínguez, AM; López-Santiago, LF; Navarrete, A; Vega, AV | 1 |
| Darcy, DP; Isaacson, JS; Murphy, GJ | 1 |
| Damaj, MI | 1 |
| Borgens, R; Nehrt, A; Rodgers, R; Shapiro, S; Shi, R | 1 |
| Du, L; Shen, J; Wang, W; Wang, Z; Xing, D; Yip, S | 1 |
| Cano-Abad, MF; de Diego, AM; Díaz-Prieto, N; Gallego-Sandín, S; García, AG; Herrera-Peco, I; López, MG; Ruiz-Nuño, A | 1 |
| Darcy, DP; Isaacson, JS | 1 |
| Gold, MS; Zhang, XL | 1 |
| Cortés-Gil, L; de Diego, AM; Fernández-Morales, JC; García, AG | 1 |
| Hamilton, JB; Lu, CB; Powell, AD; Toescu, EC; Vreugdenhil, M | 1 |
| Kobayashi, Y; Matsui, T; Tanaka, M; Wang, Z; Watanabe, S | 1 |
| An Haack, K; Bennett, MJ; Li, H; Narayan, SB; Tan, L; Warnock, A | 1 |
1 review(s) available for bay-k-8644 and nimodipine
| Article | Year |
|---|---|
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Peripheral Nervous System Diseases; Pulmonary Disease, Chronic Obstructive; Transient Receptor Potential Channels | 2010 |
133 other study(ies) available for bay-k-8644 and nimodipine
| Article | Year |
|---|---|
Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Inhibitors; Guinea Pigs; Humans; Isradipine; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptors, Purinergic P1; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship | 1996 |
Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alternative Splicing; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Kidney; Membrane Potentials; Molecular Sequence Data; Nimodipine; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Signal Transduction; Transfection; Xenopus | 2001 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Characterization of the calcium response to thyrotropin-releasing hormone (TRH) in cells transfected with TRH receptor complementary DNA: importance of voltage-sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cell Line; DNA; Endothelins; HeLa Cells; Humans; Ion Channel Gating; Mice; Neuroglia; Nimodipine; Pituitary Neoplasms; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Recombinant Proteins; Stimulation, Chemical; Terpenes; Thapsigargin; Thyrotropin-Releasing Hormone; Transfection; Tumor Cells, Cultured | 1992 |
Measurement of intracellular cadmium with fluorescent dyes. Further evidence for the role of calcium channels in cadmium uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Biological Transport; Cadmium; Calcium Channels; Fluorescent Dyes; Fura-2; Kinetics; Nimodipine; Pituitary Neoplasms; Spectrometry, Fluorescence; Tumor Cells, Cultured | 1992 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Cytosolic Ca2+ in melanotrophs: pharmacological insights into regulatory influences of electrical activity and ion channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cytosol; Egtazic Acid; Ion Channels; Male; Membrane Potentials; Nimodipine; Pituitary Gland; Potassium; Rats; Rats, Inbred Strains; Tetrodotoxin; Veratridine | 1990 |
Opiate analgesia and calcium channels modulation by dihydropyridines under acute and tolerant conditions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesia; Animals; Calcium Channels; Dihydropyridines; Drug Tolerance; Fentanyl; Male; Nimodipine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sufentanil | 1990 |
Calcium antagonists inhibit met-enkephalin immunoreactive material release: in vitro and ex vivo experiments.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Corpus Striatum; Enkephalin, Methionine; In Vitro Techniques; Male; Nimodipine; Rats; Rats, Inbred Strains | 1990 |
Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal; doses required, stereospecificity and actions of Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Mice; Nimodipine; Nitrendipine; Oxadiazoles; Stereoisomerism; Substance Withdrawal Syndrome; Time Factors | 1990 |
Excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzofurans; Calcium; Cell Survival; Cells, Cultured; Electrophysiology; Fluorescent Dyes; Fura-2; Glycine; Hippocampus; Magnesium; Neurons; Nimodipine; Pyramidal Tracts; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Synapses | 1990 |
Calcium release from pituitary secretory granules: modulation by thiols, disulfides, and dihydropyridine calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cattle; Cysteine; Cystine; Cytoplasmic Granules; Dihydropyridines; Disulfides; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Mercaptoethanol; Nifedipine; Nimodipine; Pituitary Gland; Potassium Chloride; Sulfhydryl Compounds | 1990 |
Thapsigargin, but not caffeine, blocks the ability of thyrotropin-releasing hormone to release Ca2+ from an intracellular store in GH4C1 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Cell Line; Inositol Phosphates; Kinetics; Nimodipine; Pituitary Neoplasms; Plants, Medicinal; Prolactin; Terpenes; Thapsigargin; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1990 |
Effects of calcium channel modulators on the proliferation of mouse spleen lymphocytes in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Chloride; Cell Division; DNA; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Nimodipine; Pyridines; Spleen | 1990 |
Actions and interactions of calcium modulators and ethanol on rat atrial membrane potentials.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Atrial Function; Drug Interactions; Ethanol; Heart Atria; Membrane Potentials; Nimodipine; Rats | 1990 |
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Blockers; Dihydropyridines; Electrochemistry; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nimodipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1990 |
Rat cerebral cortical synaptoneurosomal membranes. Structure and interactions with imidazobenzodiazepine and 1,4-dihydropyridine calcium channel drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Calcium Channel Blockers; Cell Membrane; Cerebral Cortex; Dihydropyridines; Flumazenil; Microscopy, Electron; Models, Molecular; Myelin Basic Protein; Neurons; Nimodipine; Protein Conformation; Rats; Receptors, Cholinergic; Receptors, GABA-A; Ryanodine Receptor Calcium Release Channel; Synaptosomes; X-Ray Diffraction | 1990 |
The effects of dihydropyridine calcium channel modulators on pentylenetetrazole convulsions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Male; Mice; Nifedipine; Nimodipine; Seizures | 1990 |
Dual mechanisms of inhibition by dopamine of basal and thyrotropin-releasing hormone-stimulated inositol phosphate production in anterior pituitary cells. Evidence for an inhibition not mediated by voltage-dependent Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Chromatography, High Pressure Liquid; Dopamine; Egtazic Acid; Female; Inositol Phosphates; Ionomycin; Kinetics; Models, Biological; Nimodipine; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1990 |
Inotropic effects of ethanol and dihydropyridines on the guinea pig heart atrial muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Ethanol; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Nimodipine | 1990 |
Depolarization-dependent actions of dihydropyridines on synaptic transmission in the in vitro rat hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Dihydropyridines; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Light; Membrane Potentials; Neurons; Nifedipine; Nimodipine; Perfusion; Potassium; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1990 |
Effects of the 1,4-dihydropyridine-sensitive L-type calcium channel antagonist nimodipine and calcium channel activator Bay K 8644 on local cerebral glucose utilization in the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Autoradiography; Brain; Deoxyglucose; Hippocampus; Male; Nimodipine; Rats; Rats, Inbred Strains | 1990 |
Multiple conductance levels of the dihydropyridine-sensitive calcium channel in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cell Line; Dihydropyridines; Electric Conductivity; Humans; Nimodipine; Pituitary Gland, Anterior | 1990 |
Pituitary calcium channel modulation and regulation of prolactin gene expression.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cell Line; Chromosome Deletion; DNA; Enhancer Elements, Genetic; Gene Expression Regulation; Nimodipine; Pituitary Gland; Prolactin; Promoter Regions, Genetic | 1990 |
The discriminative stimulus properties of cocaine: effects of BAY K 8644 and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cocaine; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Nimodipine; Rats; Rats, Inbred Strains; Reinforcement Schedule; Reinforcement, Psychology | 1990 |
Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aging; Analysis of Variance; Animals; Catheterization; Conditioning, Eyelid; Dose-Response Relationship, Drug; Female; Flunarizine; Hippocampus; Neurons; Nifedipine; Nimodipine; Rabbits; Software | 1990 |
Voltage-dependent calcium channels regulate GH4 pituitary cell proliferation at two stages of the cell cycle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cell Cycle; Cell Division; Cell Line; Mitosis; Nimodipine; Pituitary Gland; Potassium; Rats; S Phase | 1991 |
High- and low-threshold calcium currents in neurons acutely isolated from rat sensorimotor cortex.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Cadmium; Calcium; Evoked Potentials; In Vitro Techniques; Membrane Potentials; Mollusk Venoms; Neurons; Nickel; Nimodipine; omega-Conotoxins; Parietal Lobe; Peptides, Cyclic; Rats; Somatosensory Cortex | 1990 |
Calcium channel modulation by dihydropyridines modifies sufentanil-induced antinociception in acute and tolerant conditions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics, Opioid; Animals; Calcium Channels; Drug Interactions; Drug Tolerance; Fentanyl; Male; Nimodipine; Rats; Rats, Inbred Strains; Stereoisomerism; Sufentanil | 1990 |
Distribution of dihydropyridine and omega-conotoxin-sensitive calcium currents in acutely isolated rat and frog sensory neuron somata: diameter-dependent L channel expression in frog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channels; Dihydropyridines; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Kinetics; Membrane Potentials; Mollusk Venoms; Neurons, Afferent; Nimodipine; omega-Conotoxin GVIA; Peptides, Cyclic; Ranidae; Rats; Species Specificity | 1991 |
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats | 1991 |
Ca2+ channel modulation by dihydropyridines modifies sufentanil-induced respiratory depression in cats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Stem; Calcium Channels; Cats; Female; Fentanyl; Male; Medulla Oblongata; Nimodipine; Respiration; Saline Solution, Hypertonic; Sufentanil | 1991 |
Ca2+ channel agonists enhance thyrotropin-releasing hormone-induced inositol phosphates and prolactin secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Radioisotopes; Dihydropyridines; Female; In Vitro Techniques; Inositol Phosphates; Nimodipine; Perfusion; Prolactin; Pyridines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thyrotropin-Releasing Hormone | 1991 |
Effects of calcium channel agonist and antagonists on calcium-dependent events in CA1 hippocampal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Hippocampus; Male; Neurons; Nimodipine; omega-Conotoxin GVIA; Peptides, Cyclic; Rats; Rats, Inbred Strains; Synapses; Verapamil | 1991 |
Effect of calcium on presynaptic inhibition in the isolated spinal cord of newborn rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium; Electrophysiology; Ganglia, Spinal; Nimodipine; Rats; Spinal Cord; Synapses | 1991 |
The involvement of L-type calcium channels in heterosynaptic long-term depression in the hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antibodies, Monoclonal; Calcium Channels; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Nimodipine; Picrotoxin; Rats; Rats, Inbred Strains; Synapses | 1991 |
Regulation of single calcium channels in cerebral arteries by voltage, serotonin, and dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Basilar Artery; Calcium; Calcium Channels; Dihydropyridines; Electric Conductivity; Electrophysiology; Ion Channel Gating; Nimodipine; Rabbits; Serotonin | 1991 |
Calcium antagonistic properties of the sesquiterpene T-cadinol: a comparison with nimodipine in the isolated rat aorta.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium Channel Blockers; Muscle Contraction; Muscle, Smooth, Vascular; Nimodipine; Rats; Rats, Inbred Strains; Sesquiterpenes | 1991 |
Different receptor affinities of the enantiomers of BAY K 8644, a dihydropyridine Ca channel activator.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; In Vitro Techniques; Kinetics; Nicotinic Acids; Nifedipine; Nimodipine; Rats; Receptors, Drug; Stereoisomerism | 1985 |
Calcium channels in planar lipid bilayers: insights into mechanisms of ion permeation and gating.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cattle; Electric Conductivity; Heart; In Vitro Techniques; Ion Channels; Lipid Bilayers; Nicotinic Acids; Nifedipine; Nimodipine; Potassium; Sarcolemma; Sodium | 1986 |
Bay K 8644 stimulation of calcium entry and endogenous dopamine release in rat striatal synaptosomes antagonized by nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Corpus Striatum; Dopamine; Electric Stimulation; Kinetics; Male; Nicotinic Acids; Nifedipine; Nimodipine; Potassium Chloride; Rats; Rats, Inbred Strains; Synaptosomes | 1986 |
Enhancement of depolarization-induced synaptosomal calcium uptake and neurotransmitter release by Bay K8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cerebral Cortex; Ethanol; Glutamates; Glutamic Acid; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Norepinephrine; Potassium; Rats; Synaptosomes; Veratrine | 1986 |
Muscarinic cholinergic enhancement of inositide turnover in cerebral nerve endings is not mediated by calcium uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcimycin; Calcium; Carbachol; Cinnarizine; Flunarizine; Male; Nerve Endings; Nicotinic Acids; Nifedipine; Nimodipine; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Inbred Strains; Verapamil; Veratridine | 1986 |
Effects of Bay K 8644 on cat adrenal catecholamine secretory responses to A23187 or ouabain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcimycin; Calcium; Catecholamines; Cats; Dose-Response Relationship, Drug; Drug Synergism; Female; Magnesium; Male; Nicotinic Acids; Nifedipine; Nimodipine; Ouabain; Potassium; Sodium | 1986 |
Dihydropyridine calcium agonists selectively enhance resistance artery myogenic tone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; In Vitro Techniques; Ion Channels; Male; Nimodipine; Potassium; Pyridines; Rabbits; Vasoconstriction | 1986 |
Interaction of 1,4-dihydropyridines with somatic Ca currents in hippocampal CA1 neurones of the guinea pig in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neural Conduction; Nimodipine; Receptors, Nicotinic | 1986 |
Excitatory action of BAYK8644 on hippocampal pyramidal neurones of the guinea pig in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcimycin; Calcium; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Potentials; Neurons; Nimodipine; Potassium | 1986 |
Activation of dihydropyridine receptors differentially regulates temperature responses in rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Body Temperature Regulation; Brain; Ca(2+) Mg(2+)-ATPase; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Male; Nimodipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1986 |
Effects of Bay K 8644 and other dihydropyridines on basal and potassium-evoked output of MSH from mouse melanotrophs in vitro.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Culture Techniques; Drug Interactions; Ion Channels; Male; Melanocyte-Stimulating Hormones; Mice; Nifedipine; Nimodipine; Pituitary Gland, Anterior; Potassium | 1986 |
Dihydropyridine modulators of voltage-sensitive Ca2+ channels specifically regulate prolactin production by GH4C1 pituitary tumor cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Line; Growth Hormone; Ion Channels; Kinetics; Nimodipine; Pituitary Neoplasms; Prolactin; Rats | 1987 |
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1987 |
The Ca++-antagonist nimodipine decreases and the Ca++-agonist Bay K 8644 increases catecholamine synthesis in mouse brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 5-Hydroxytryptophan; Animals; Brain; Catecholamines; Corpus Striatum; Dihydroxyphenylalanine; Ion Channels; Limbic System; Mice; Nimodipine | 1987 |
BAY K 8644 increases release of acetylcholine at the murine neuromuscular junction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Dihydropyridines; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neuromuscular Junction; Nimodipine; Rats; Rats, Inbred Strains | 1987 |
Regional distribution of calcium channel ligand (1,4-dihydropyridine) binding sites and 45Ca2+ uptake processes in rat brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channels; Caudate Nucleus; Cell Membrane; Cerebellum; Cerebral Cortex; Dihydropyridines; Hippocampus; Male; Nimodipine; Olfactory Bulb; Potassium; Rats; Receptors, Nicotinic; Synaptosomes; Tissue Distribution | 1987 |
Morphine withdrawal in cortical slices: suppression by Ca2+-channel inhibitors of abstinence-induced [3H]-noradrenaline release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cerebral Cortex; Dihydropyridines; Disease Models, Animal; In Vitro Techniques; Ion Channels; Morphine; Naloxone; Nimodipine; Norepinephrine; Rats; Substance Withdrawal Syndrome; Tritium | 1988 |
Anticonvulsant profile of the dihydropyridine calcium channel antagonists, nitrendipine and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Aspartic Acid; Atmospheric Pressure; Calcium Channel Blockers; Electrophysiology; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Strychnine | 1988 |
Activation of protein kinase C and L calcium channels enhances binding of biotinylated corticotropin-releasing hormone by anterior pituitary corticotropes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Angiotensin II; Animals; Arginine Vasopressin; Biotin; Calcium Channels; Corticotropin-Releasing Hormone; Enzyme Activation; Male; Nimodipine; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Second Messenger Systems; Spectrophotometry; Tetradecanoylphorbol Acetate | 1989 |
Effects of nimodipine, Bay K 8644 and pinacidil on alpha 1- and alpha 2-adrenoceptor-mediated vasoconstriction in human hand veins.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adolescent; Adrenergic alpha-Antagonists; Adult; Aged; Female; Guanidines; Hand; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Nimodipine; Pinacidil; Vasoconstriction; Veins | 1988 |
Effects of dihydropyridine drugs on reversal by imipramine of helpless behavior in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Avoidance Learning; Dihydropyridines; Dose-Response Relationship, Drug; Electroshock; Helplessness, Learned; Imipramine; Male; Nimodipine; Rats; Rats, Inbred Strains | 1989 |
Pituitary thyrotropin-releasing hormone (TRH) receptors: effects of TRH, drugs mimicking TRH action, and chlordiazepoxide.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcimycin; Cell Line; Chlordiazepoxide; Down-Regulation; Nimodipine; Pituitary Gland; Prolactin; Rats; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone | 1989 |
Calcium channels in isolated rat dorsal horn neurones, including labelled spinothalamic and trigeminothalamic cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cadmium; Calcium; Calcium Channels; Cobalt; In Vitro Techniques; Neurons; Nickel; Nimodipine; Rats; Spinal Cord; Thalamus; Time Factors; Trigeminal Nucleus, Spinal | 1989 |
The stimulus properties of cocaine: effects of BAY K 8644 and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arousal; Brain; Cocaine; Dose-Response Relationship, Drug; Male; Nimodipine; Rats; Rats, Inbred Strains | 1989 |
Actions and interactions of dihydropyridines and ethanol on the rat sinus node.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Dihydropyridines; Drug Interactions; Ethanol; In Vitro Techniques; Male; Microelectrodes; Myocardial Contraction; Nimodipine; Rats; Rats, Inbred Strains; Sinoatrial Node | 1989 |
Interaction of the calcium channel activating 3H-BAY K 8644 and inhibiting 3H-verapamil with specific receptor sites on cultured beating myocardial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channel Blockers; Cells, Cultured; Kinetics; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Receptors, Drug; Verapamil | 1984 |
Binding properties of a novel calcium channel activating dihydropyridine in monolayer cultures of beating myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium; Cells, Cultured; Female; Ion Channels; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Pregnancy; Rats; Time Factors | 1984 |
The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Cell Line; Clone Cells; Kinetics; Mice; Nicotinic Acids; Nifedipine; Nimodipine; Pituitary Neoplasms; Prolactin | 1984 |
Dihydropyridine calcium agonist and antagonist effects on aldosterone secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Dantrolene; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Stimulation, Chemical | 1984 |
Effects of dihydropyridine calcium channel modulators in the heart: pharmacological and radioligand binding correlations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Myocardial Contraction; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rats; Stimulation, Chemical | 1984 |
The nicotinic acetylcholine receptor of the bovine chromaffin cell, a new target for dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cytosol; Dihydropyridines; Dimethylphenylpiperazinium Iodide; Electrophysiology; Enterochromaffin Cells; Fura-2; Manganese; Membrane Potentials; Nimodipine; Potassium; Receptors, Cholinergic | 1993 |
Cadmium toxicity in rat pheochromocytoma cells: studies on the mechanism of uptake.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Cadmium; Calcium Channels; Electrophysiology; Fura-2; Ion Transport; Nimodipine; Pheochromocytoma; Rats; Tumor Cells, Cultured | 1994 |
Calcium entry blockers stimulate vasoproliferation on the chick chorioallantoic membrane.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allantois; Animals; Cell Division; Chick Embryo; Chorion; Dose-Response Relationship, Drug; Nifedipine; Nimodipine; Verapamil | 1993 |
L-type voltage-sensitive calcium channel antagonists block heterosynaptic long-term depression in the dentate gyrus of anaesthetized rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Electric Stimulation; Electrochemistry; Hippocampus; Long-Term Potentiation; Male; Nifedipine; Nimodipine; Rats; Rats, Sprague-Dawley; Synapses | 1994 |
Appearance of depolarization- and maitotoxin-induced [Ca2+]i elevation in single LAN-1 human neuroblastoma cells on exposure to retinoic acid.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Cell Differentiation; Cytophotometry; Humans; Marine Toxins; Membrane Potentials; Neuroblastoma; Nimodipine; omega-Conotoxin GVIA; Oxocins; Peptides; Potassium; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Tumor Cells, Cultured | 1994 |
Analgesic and reinforcing effects of morphine in mice. Influence of Bay K-8644 and nimodipine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intravenous; Male; Mice; Morphine; Nimodipine; Nociceptors; Pain Measurement; Reaction Time; Reinforcement, Psychology; Self Administration | 1994 |
Role of L-type calcium channel modulation in nonconvulsive epilepsy in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channels; Electrodes, Implanted; Electroencephalography; Epilepsy, Absence; Male; Nimodipine; Rats; Rats, Wistar; Seizures | 1995 |
The dihydropyridine nitrendipine inhibits [3H]MK 801 binding to mouse brain sections.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Autoradiography; Binding, Competitive; Brain; Calcium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; N-Methylaspartate; Nifedipine; Nimodipine; Nitrendipine; Software; Verapamil | 1994 |
Differential contribution of L- and N-type calcium channels on rat hippocampal acetylcholine release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Hippocampus; Male; Nimodipine; Potassium; Rats; Rats, Sprague-Dawley; Synaptosomes | 1994 |
Pharmacological types of calcium channels and their modulation by baclofen in cerebellar granules.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Calcium Channel Blockers; Calcium Channels; Cell Survival; Cells, Cultured; Cerebellum; Kinetics; Neurons; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Rats; Spider Venoms; Time Factors | 1995 |
Functional modulation of human "ganglionic-like" neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cadmium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Humans; Isradipine; Neuroblastoma; Neurons; Nicotine; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Receptors, Nicotinic; Spider Venoms; Tumor Cells, Cultured; Verapamil | 1995 |
Contribution of L- and non-L-type calcium channels to voltage-gated calcium current and glucose-dependent insulin secretion in HIT-T15 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Nimodipine; omega-Conotoxins; Pancreatic Neoplasms; Peptides; Rats; Tumor Cells, Cultured | 1995 |
Modulation of N-type calcium channels in bullfrog sympathetic neurons by luteinizing hormone-releasing hormone: kinetics and voltage dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Electric Conductivity; Electrophysiology; Ganglia, Sympathetic; Gonadotropin-Releasing Hormone; Ion Channel Gating; Kinetics; Neurons; Nimodipine; omega-Conotoxins; Peptides, Cyclic; Rana catesbeiana | 1993 |
L-type Ca2+ channel ligands modulate morphine effects on the hypothalamus-pituitary-adrenocortical axis in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Corticosterone; Dopamine; Drug Synergism; Hypothalamo-Hypophyseal System; Male; Morphine; Neurosecretory Systems; Nimodipine; Norepinephrine; Pituitary-Adrenal System; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Effect of nimodipine, diltiazem and BAY K 8644 on the behavioural and neurochemical changes associated with naloxone-precipitated withdrawal in the rat. A comparison with clonidine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Brain Chemistry; Clonidine; Diltiazem; Hydroxyindoleacetic Acid; Male; Morphine Dependence; Naloxone; Nimodipine; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Substance Withdrawal Syndrome | 1993 |
Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Oxidoreductases; Animals; Calcium Channel Blockers; Cell Line; Endotoxins; Enzyme Induction; Escherichia coli; Kinetics; Lipopolysaccharides; Macrophages; Mice; Nimodipine; Nisoldipine; Nitrendipine; Nitric Oxide Synthase | 1993 |
The Ca2+ channel agonist Bay K 8644 induces central respiratory depression in cats, an effect blocked by naloxone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Calcium Channels; Cats; Drug Interactions; Female; Male; Naloxone; Nimodipine; Respiration; Stereoisomerism | 1993 |
Dihydropyridines and verapamil inhibit voltage-dependent K+ current in isolated outer hair cells of the guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cochlea; Guinea Pigs; Hair Cells, Auditory, Outer; Membrane Potentials; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channel Blockers; Quinine; Verapamil | 1995 |
Depolarization-evoked increases in cytosolic calcium concentration in isolated smooth muscle cells of rat portal vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cytophotometry; Cytosol; Dihydropyridines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nimodipine; Patch-Clamp Techniques; Portal Vein; Rats; Rats, Sprague-Dawley; Ryanodine; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Antidystonic effects of L-type Ca2+ channel antagonists in a hamster model of idiopathic dystonia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cricetinae; Diltiazem; Dystonia; Female; Male; Nimodipine | 1996 |
Effect of chronic administration of dihydropyridine Ca2+ channel ligands on sufentanil-induced tolerance to mu- and kappa-opioid agonists in the guinea pig ileum myenteric plexus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Analgesics, Opioid; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Drug Tolerance; Female; Guinea Pigs; Ileum; Infusion Pumps, Implantable; Male; Myenteric Plexus; Nimodipine; Pyrrolidines; Sufentanil | 1996 |
Modulation of kappa-opioid receptor mediated tolerance in the guinea-pig ileum by chronic co-administration of dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Nimodipine; Pyrrolidines; Receptors, Opioid, kappa | 1996 |
Thyrotropin (TSH)-releasing hormone stimulates TSH beta promoter activity by two distinct mechanisms involving calcium influx through L type Ca2+ channels and protein kinase C.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cell Line; Embryo, Mammalian; Enzyme Activation; Humans; Kidney; Nimodipine; Promoter Regions, Genetic; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate; Thyrotropin; Thyrotropin-Releasing Hormone; Transfection | 1996 |
Time-varying alterations in the f2-f1 DPOAE response to continuous primary stimulation. II. Influence of local calcium-dependent mechanisms.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acoustic Stimulation; Animals; Calcium; Calcium Channel Blockers; Chelating Agents; Cochlear Microphonic Potentials; Dimethyl Sulfoxide; Egtazic Acid; Female; Guinea Pigs; Hair Cells, Auditory, Outer; Magnesium; Male; Nimodipine; Otoacoustic Emissions, Spontaneous; Perilymph | 1996 |
The effect of L-type calcium channel modulators on the mobilization of intracellular calcium stores in guinea-pig intestinal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Diazoxide; Fura-2; Guinea Pigs; Histamine; Ileum; Isometric Contraction; Muscle, Smooth; Nimodipine; Ryanodine; Thapsigargin | 1996 |
The calcium channel agonist BAY k 8644 reduces ethanol intake and preference in alcohol-preferring AA rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Animals; Calcium Channel Agonists; Dose-Response Relationship, Drug; Ethanol; Female; Food Preferences; Injections, Intraperitoneal; Male; Nimodipine; Rats; Stereoisomerism; Time Factors | 1996 |
Modulation of cocaine intravenous self-administration in drug-naive animals by dihydropyridine Ca2+ channel modulators.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Nimodipine; Rats; Rats, Wistar; Self Administration | 1996 |
Partial characterization of K(+)-induced increase in [Ca2+]cyt and GnRH release in GT1-7 neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Cytosol; Electrophysiology; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Mollusk Venoms; Nimodipine; Osmolar Concentration; Potassium | 1995 |
Effects of N- and L-type calcium channel antagonists on the responses of nociceptive spinal cord neurons to mechanical stimulation of the normal and the inflamed knee joint.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Diltiazem; Drug Evaluation, Preclinical; Inflammation; Knee Joint; Male; Neurons; Nimodipine; Nociceptors; omega-Conotoxin GVIA; Peptides; Rats; Rats, Wistar; Reference Values; Spinal Cord; Stress, Mechanical | 1996 |
Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Ganglia, Spinal; Neuroprotective Agents; Nimodipine; Rats; Rats, Sprague-Dawley; Riluzole; Thiazoles | 1997 |
Effects of dihydropyridine Ca2+ channel blockers on the discriminative stimulus and the motor impairing effects of (+/-)-Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Discrimination, Psychological; Male; Mice; Motor Activity; Nicardipine; Nifedipine; Nimodipine | 1997 |
A role for L-type calcium channels in developmental regulation of transmitter phenotype in primary sensory neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Female; Gene Expression Regulation, Developmental; Ion Channel Gating; Long-Term Potentiation; Membrane Potentials; Neuronal Plasticity; Neurons, Afferent; Neurotransmitter Agents; Nimodipine; omega-Conotoxin GVIA; Peptides; Phenotype; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Substance P; Tyrosine 3-Monooxygenase | 1998 |
Functional characterization of ion permeation pathway in the N-type Ca2+ channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Cell Line; Cricetinae; Ion Channel Gating; Ion Transport; Kidney; Kinetics; Mesocricetus; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Rabbits; Recombinant Fusion Proteins; Spider Venoms; Strontium; Transfection | 1998 |
L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Aorta; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Differentiation; Cell Line; Culture Media; Dihydropyridines; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nimodipine; Patch-Clamp Techniques; Rats; Tretinoin | 1998 |
Specificity in the interaction of HVA Ca2+ channel types with Ca2+-dependent AHPs and firing behavior in neocortical pyramidal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Ion Transport; Membrane Potentials; Motor Cortex; Nerve Tissue Proteins; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Pyramidal Cells; Somatosensory Cortex; Spider Venoms | 1998 |
Structure and functional characterization of a novel human low-voltage activated calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Barium; Benzimidazoles; Blotting, Northern; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, T-Type; Cells, Cultured; Cloning, Molecular; Diuretics; DNA, Complementary; Electric Stimulation; Electrophysiology; Humans; Ion Channel Gating; Kidney; Kinetics; Membrane Potentials; Mibefradil; Molecular Sequence Data; Nickel; Nimodipine; Oocytes; Recombinant Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Tetrahydronaphthalenes; Transcription, Genetic; Verapamil; Xenopus | 1999 |
Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein-1 element.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Genes, fos; Genes, jun; Gonadotropin-Releasing Hormone; Mice; Nimodipine; Promoter Regions, Genetic; Protein Kinase C; Receptors, LHRH; Response Elements; Steroidogenic Factor 1; Transcription Factor AP-1; Transcription Factors | 1999 |
Effects of excitatory amino acids and nimodipine on calcium currents in cultured rat cortical neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Aspartic Acid; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acids; Glutamic Acid; Nimodipine; Rats; Rats, Wistar | 1999 |
Effects of mutations causing hypokalaemic periodic paralysis on the skeletal muscle L-type Ca2+ channel expressed in Xenopus laevis oocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Gene Expression; Hypokalemic Periodic Paralysis; Muscle, Skeletal; Mutation; Nimodipine; Oocytes; Patch-Clamp Techniques; Rabbits; RNA, Complementary; Xenopus laevis | 1999 |
Potassium-induced secretion of melanocyte-stimulating hormone from the melanotrophs of the neurointermediate lobe of the lizard Anolis carolinensis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Lizards; Melanocyte-Stimulating Hormones; Nimodipine; Pituitary Gland; Potassium | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Differential expression of high- and two types of low-voltage-activated calcium currents in rod and cone bipolar cells of the rat retina.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Axons; Bicuculline; Cadmium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Evoked Potentials; gamma-Aminobutyric Acid; Membrane Potentials; Nickel; Nimodipine; Protein Kinase C; Quinine; Rats; Rats, Long-Evans; Receptors, GABA; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Tetrodotoxin | 2000 |
L-type calcium channel activity regulates sodium channel levels in rat pituitary GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Cycloheximide; Dactinomycin; Electrophysiology; Ion Channel Gating; Nimodipine; Nucleic Acid Synthesis Inhibitors; Pituitary Gland; Protein Synthesis Inhibitors; Rats; Saxitoxin; Sodium Channels; Transcription, Genetic | 2000 |
Modulation of the ethanol-like discriminative stimulus effects of diazepam and phencyclidine by L-type voltage-gated calcium-channel ligands in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Central Nervous System Depressants; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Modulators; Isradipine; Ligands; Male; N-Methylaspartate; Nifedipine; Nimodipine; Phencyclidine; Rats; Rats, Long-Evans | 2000 |
Opposite effects of T- and L-type Ca(2+) channels blockers in generalized absence epilepsy.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dose-Response Relationship, Drug; Epilepsy, Absence; Ethosuximide; Male; Nimodipine; omega-Conotoxin GVIA; Rats | 2000 |
E(f)-current contributes to whole-cell calcium current in low calcium in frog sympathetic neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Ganglia, Sympathetic; Ion Channel Gating; Neurons; Nickel; Nimodipine; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Rana catesbeiana | 2001 |
Role of L-type Ca2+ channels in transmitter release from mammalian inner hair cells. II. Single-neuron activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Female; Guinea Pigs; Hair Cells, Auditory, Inner; Male; Mammals; Nimodipine; Synaptic Transmission | 2002 |
Effects of methylmercury on human neuronal L-type calcium channels transiently expressed in human embryonic kidney cells (HEK-293).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Embryo, Mammalian; Humans; Kidney; Kinetics; Membrane Potentials; Methylmercury Compounds; Neurons; Nimodipine; Recombinant Proteins; Transfection | 2002 |
Calcium channels involved in noradrenaline release from sympathetic neurones in rabbit carotid artery.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Carotid Artery, Common; Electric Stimulation; Female; Male; Neurons; Nifedipine; Nimodipine; Norepinephrine; omega-Conotoxin GVIA; Potassium Channel Blockers; Rabbits; Sympathetic Nervous System; Time Factors | 2003 |
AII amacrine cells express L-type calcium channels at their output synapses.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amacrine Cells; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; In Vitro Techniques; Intracellular Fluid; Membrane Potentials; Mice; Mice, Inbred C57BL; Nimodipine; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; Synapses | 2003 |
L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Drug Interactions; Gene Expression Regulation; NAV1.2 Voltage-Gated Sodium Channel; NAV1.3 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Nimodipine; Nucleic Acid Amplification Techniques; Pituitary Gland; Protein Subunits; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sodium Channels; Up-Regulation | 2003 |
Intraglomerular inhibition: signaling mechanisms of an olfactory microcircuit.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Bicuculline; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Dendrites; Diagnostic Imaging; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Conduction; Neural Inhibition; Neural Networks, Computer; Neurons; Nickel; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phosphinic Acids; Potassium; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
Calcium-acting drugs modulate expression and development of chronic tolerance to nicotine-induced antinociception in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Drug Tolerance; Enzyme Activation; Enzyme Inhibitors; Injections, Spinal; Male; Mice; Nicotine; Nicotinic Agonists; Nimodipine; Pain Measurement; Reaction Time; Spinal Cord; Verapamil | 2005 |
The critical role of voltage-dependent calcium channel in axonal repair following mechanical trauma.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Axons; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Nimodipine; Spinal Cord Injuries; Time Factors; Wound Healing | 2007 |
Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Benzopyrans; Caesalpinia; Caffeine; Calcium; Diltiazem; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Indenes; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide Synthase; Phenylephrine; Pinacidil; Potassium Chloride; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2008 |
Bcl2 mitigates Ca2+ entry and mitochondrial Ca2+ overload through downregulation of L-type Ca2+ channels in PC12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; bcl-Associated Death Protein; Benzopyrans; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Down-Regulation; Ionomycin; Ionophores; Membrane Potentials; Mitochondria; Nimodipine; Nitriles; Patch-Clamp Techniques; PC12 Cells; Rats; Transfection | 2008 |
L-type calcium channels govern calcium signaling in migrating newborn neurons in the postnatal olfactory bulb.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Movement; Doublecortin Domain Proteins; Egtazic Acid; Excitatory Amino Acid Agents; Fluoresceins; Green Fluorescent Proteins; In Vitro Techniques; Membrane Potentials; Mice; Microscopy, Confocal; Microtubule-Associated Proteins; Neurons; Neuropeptides; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2009 |
Dihydropyridine block of voltage-dependent K+ currents in rat dorsal root ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dose-Response Relationship, Drug; Ganglia, Spinal; In Vitro Techniques; Male; Neurons; Nifedipine; Nimodipine; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley | 2009 |
Differences in the quantal release of catecholamines in chromaffin cells of rat embryos and their mothers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Catecholamines; Chromaffin Cells; Embryo, Mammalian; Female; Humans; Nimodipine; omega-Conotoxins; Potassium; Pregnancy; Rats; Rats, Wistar | 2009 |
Effect of ageing on CA3 interneuron sAHP and gamma oscillations is activity-dependent.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; CA3 Region, Hippocampal; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Chelating Agents; Excitatory Amino Acid Agonists; Fura-2; Interneurons; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Nimodipine; Periodicity | 2011 |
Trp-His, a vasorelaxant di-peptide, can inhibit extracellular Ca2+ entry to rat vascular smooth muscle cells through blockade of dihydropyridine-like L-type Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Proliferation; Dipeptides; Male; Muscle, Smooth, Vascular; Nifedipine; Nimodipine; Rats; Rats, Wistar; Verapamil | 2010 |
Screening for calcium channel modulators in CLN3 siRNA knock down SH-SY5Y neuroblastoma cells reveals a significant decrease of intracellular calcium levels by selected L-type calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line, Tumor; Child; Drug Evaluation, Preclinical; Flunarizine; Humans; Intracellular Space; Membrane Glycoproteins; Molecular Chaperones; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Nicardipine; Nifedipine; Nimodipine; Potassium Chloride; RNA Interference; RNA, Small Interfering | 2011 |