bay-k-8644 and isoproterenol

bay-k-8644 has been researched along with isoproterenol in 137 studies

Research

Studies (137)

Timeframe	Studies, this research(%)	All Research%
pre-1990	35 (25.55)	18.7374
1990's	70 (51.09)	18.2507
2000's	20 (14.60)	29.6817
2010's	12 (8.76)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alvarez, JL; Vassort, G	1
Bowmer, CJ; Robinson, SC; Yates, MS	1
Hirano, Y; January, CT; Moscucci, A	1
Lory, P; Nargeot, J	1
Harbon, S; Khac, LD; Mokhtari, A; Renner, M	1
Jiang, B; Ke, J; Zhang, GQ	1
Kurtz, A; Scholz, H	1
Broadley, KJ; Urquhart, RA	2
Bishopric, NH; Sato, B; Webster, KA	1
Kennedy, RH; Ruch, S; Seifen, E	1
Chiappe de Cingolani, G; Mattiazzi, A; Mundiña, C; Vittone, L	1
Charnet, P; Nargeot, J; Nerbonne, JM; Richard, S; Tiaho, F	1
Hongo, K; Konishi, M; Kurihara, S; Okazaki, O; Suda, N	1
Kasper, G; Marquez, CR; Zatz, M	1
Berthold, H; Schaad, A; Scholtysik, G	1
Fisher, R; Johnston, D	1
Bowling, N; Gengo, PJ; Hayes, JS; Kauffman, RF; Utterback, B; Wyss, VL	1
Lory, P; Nargeot, J; Nerbonne, JM; Richard, S; Tiaho, F	1
Lynch, C	1
Felbel, J; Hofmann, F; Peper, K; Welling, A	2
Watkins, WD; Whorton, AR; Xuan, YT	1
Dubyak, GR; Jones, SW; Marks, TN	1
Berger, HJ; Pfeifer, A; Rupp, H; Werdan, K	1
Liepins, A; McWilliam, TM; Rankin, AJ	1
Henderson, AH; Lewis, MJ; Shah, AM	1
Fischmeister, R; Hartzell, HC; Méry, PF; Szabo, G	1
Lieu, AT; Rand, MJ; Reid, JJ	1
Gellai, M; Nichols, AJ; Ruffolo, RR	1
Drímal, J; Drímalová, L; Knézl, V; Magna, D; Tokárová, J	1
Helwig, JJ; Judes, C; Musso, MJ; Nickols, GA	1
Charnet, P; Gurney, AM; Nargeot, J; Ouadid, H; Richard, S; Tiaho, F	1
Stack, J; Surprenant, A	1
Couraud, PO; Coutinho, GC; Durieu-Trautmann, O; Strosberg, AD	1
Chambers, TJ; Gilgenkrantz, JL; Hall, TJ	1
Andersson, KE; Lindgren, S	1
Wright, G	1
Endoh, M; Takanashi, M	1
Drímal, J	1
Sperelakis, N; Tripathi, O	1
Bean, BP	1
Heisler, S	1
Hattori, Y; Hazama, S; Kanno, M; Nakao, Y	1
Hess, P; Lansman, JB; Nilius, B; Tsien, RW	1
Mitra, R; Morad, M	1
Carriot, T; Doble, A; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Néliat, G; Renault, C; Uzan, A	1
Bean, BP; Hess, P; Lansman, JB; Nilius, B; Nowycky, MC; Tsien, RW	1
Akera, T; Ng, YC; Temma, K	1
Hattori, Y; Kanno, M; Nakaya, H; Tohse, N	1
Finet, M; Godfraind, T	1
Dietz, JR	1
Ishii, K; Taira, N; Yanagisawa, T	1
Beyer, T; Gansohr, N; Gjörstrup, P; Ravens, U	1
Hume, JR	1
Pappano, AJ; Tajima, T; Tsuji, Y; Yuen, J	1
Kim, D; Marsh, JD; Smith, TW	1
Kennedy, RH; Seifen, E	1
Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Reeves, JP; Yatani, A	1
MacLeod, KM	1
Gallant, S; Gengo, P; Hawthorn, MH; Moran, JF; Rutledge, A; Triggle, DJ; Wei, XY	1
Briand, V; Laurent, S; Michel, JB; Schmitt, H; Vaxelaire, JF	2
Kennedy, RH; Seifen, AB; Seifen, E	1
Hyman, AL; Kadowitz, PJ; Lippton, HL	1
Ichihara, T; Matsumura, Y; Morimoto, S; Ohyama, T; Shinyama, H	1
Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Mattera, R; Yatani, A	1
Hashimoto, H; Taira, N; Yanagisawa, T	1
Briand, V; Lacolley, P; Laurent, S; Michel, JB; Schmitt, H; Vaxelaire, JF	1
Akahane, K; Chiba, S; Furukawa, Y; Haniuda, M; Ogiwara, Y	1
Briand, V; Laurent, S; Schmitt, H	1
Brown, AM; Imoto, Y; Schwartz, A; Yatani, A	1
Chung, M; Cohen, CJ; Thomas, G	1
Sperelakis, N; Wahler, GM	1
Satoh, K; Taira, N; Wada, Y	1
Jahnel, U; Nawrath, H; Ochi, R; Rupp, J	1
Bogdanov, K; Hallaq, H; Lakatta, E; Leaf, A; Pepe, S; Spurgeon, H	1
McArdle, JJ; Xiao, YF	1
Belardinelli, L; Song, Y	1
Joyner, RW; Kumar, R	1
Rudy, Y; Zeng, J	1
Gunasekaran, S; Tenner, TE; Young, JA	1
Hattori, Y; Kanno, M; Nakaya, H; Nishihira, J	1
Kato, N	1
Green, RD; Ma, H; Yu, HJ	1
Fischmeister, R; Frace, AM; Hartzell, HC; Méry, PF	1
Chang, MS; Chen, SA; Chiang, CE; Lin, CI; Luk, HN	1
Aggarwal, R; Boyden, PA	1
Golod, DA; Goolsby, WN; Jongsma, HJ; Joyner, RW; Kumar, R; Van Ginneken, AC; Verheijck, EE; Wagner, MB; Wilders, R	1
Fares, N; Gomez, JP; Potreau, D	1
Delpech, N; Potreau, D; Soustre, H	1
Alpert, N; Gross, R; Hebisch, S; Holubarsch, C; Just, H; Ruf, T	1
Ashraf, M; Miyawaki, H	1
Bond, M; McConnell, BK; Morano, I; Moravec, CS	1
Birder, LA; Finkel, MS; Kanai, AJ; Malinski, T; Mesaros, S; Oddis, CV	1
Crawford, FA; Doscher, MA; Hebbar, L; Houck, WV; Joshi, JD; Mukherjee, R; Spinale, FG; Thomas, CV; Wang, YH	1
Ma, L; Patterson, E; Robinson, CP; Szabo, B; Thadani, U	1
Chik, CL; Ho, AK; Negishi, T	1
Boev, KK; Fusi, F; Petkov, GV; Sgaragli, GP; Valoti, M	1
Chiba, S; Furukawa, Y; Hoyano, Y; Kasama, M; Oguchi, T	1
Backx, PH; Bouchard, RA; Liu, PP; Oudit, GY; Tsushima, RG; Wickenden, AD	1
Böhm-Pinger, MM; Dittrich, M; Fischer, IR; Fleischmann, BK; Gryshchenko, O; Hescheler, J; Igelmund, P; Soest, J; Viatchenko-Karpinski, S	1
Balfagón, G; Encabo, A; Ferrer, M; Manso, AM; Marín, J; Salaices, M	1
Abi-Gerges, N; Faivre, V; Fischmeister, R; Mebazaa, A; Méry, PF; Paqueron, X; Payen, D; Tavernier, B	1
Chik, CL; Ho, AK; Karpinski, E; Li, B; Negishi, T	1
Bansal, DD; MacGregor, RR; Puri, S; Uskoković, MR	1
Harding, SE; MacLeod, KT; Tweedie, D	1
Coyne, MD; Gwathmey, JK; Kim, CS	1
Cameron, JS; Coyne, MD; Gwathmey, JK; Kim, CS	1
Battarbee, HD; Bueno, O; Maloney, RE; O'Donnell, JM; Roerig, SC; Zavecz, JH	1
Grichenko, AS; Kokoz, YM; Korystova, AF; Lankina, DA; Markevich, NI	1
Bartel, S; Karczewski, P; Krause, EG; Schlegel, WP; Vetter, D; Wallukat, G	1
Jüngling, E; Lückhoff, A; Picht, E; Schöndube, F; Skasa, M	1
Altschuld, RA; Cheng, Y; Dumitrescu, C; Efimov, IR; Narayan, P	1
Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR	1
He, JQ; Kamp, TJ	1
Chen, X; Furukawa, S; Goldman, B; Houser, SR; Margulies, KB; Piacentino, V	1
Hino, N; Masumiya, H; Ochi, R; Tsujikawa, H	1
Cheng, LP; Cheng, YP; He, RR; Wang, YH	1
Barclay, JK; Murrant, CL; Reading, SA	1
Dhalla, NS; Saini, HK	1
Walker, NJ; Wang, D; Xie, A	1
Gupte, SA; Masumiya, H; Ochi, R; Okada, T; Song, Y; Tsujikawa, H; Watanabe, M	1
Bian, JS; Hu, LF; Pan, TT; Yong, QC	1
Berretta, RM; Chen, X; Harris, DM; Houser, SR; Margulies, KB; Piacentino, V; Zhang, X	1
Chiang, FT; Hwang, JJ; Lai, LP; Lee, JK; Lin, JL; Tsai, CT; Tseng, CD; Wang, YC; Wu, CK; Yu, CC	1
Britto, RM; Conde-Garcia, EA; Cruz, JS; Dias, AS; Estevam, Cdos S; Gondim, AN; Guatimosim, S; Lara, A; Lauton-Santos, S; Lima, AK; Oliveira, ED; Santos, AL; Souza, RC; Vasconcelos, CM	1
Gomi, S; Hirose, M; Hongo, M; Horiuchi-Hirose, M; Kashihara, T; Nakada, T; Sheng, X; Shibazaki, T; Shimojo, H; Yamada, M	1
Abraham, MR; Chang, CY; Chang, MG; de Lange, E; Garfinkel, A; Karagueuzian, HS; Marbán, E; O'Rourke, B; Qu, Z; Tung, L; Weiss, JN; Xu, L	1
Brunet, S; Catterall, WA; Scheuer, T	1
Aronsen, JM; Christensen, G; Hougen, K; Levy, FO; Meier, S; Moltzau, LR; Nguyen, CH; Osnes, JB; Qvigstad, E; Sjaastad, I; Skomedal, T; Ørstavik, Ø	1
Bai, Y; Benitez, R; Chen, SR; Clark, RB; Duff, HJ; Guo, A; Guo, J; Hove-Madsen, L; Jones, PP; Semeniuk, L; Song, LS; Vallmitjana, A; Wang, R; Zhong, X; Zhou, Q	1
Chang, ZE; Hwang, YS; Jin, JY; Kim, J; Kim, SY; Lee, BY; Moon, H; Park, J; You, J	1
Bányász, T; Hegyi, B; Horváth, B; Kistamás, K; Magyar, J; Nánási, PP; Ruzsnavszky, F; Szentandrássy, N; Váczi, K; Varró, A	1
Cao, L; Cao, YX; Li, S; Mi, YN; Ping, NN	1
Fan, J; Fan, W; Kapoor, I; Lei, J; Wang, J; Xu, H; Zhou, Y; Zhu, G	1
Acharya, A; Boeuf, H; Brungs, S; Hemmersbach, R; Hescheler, J; Lichterfeld, Y; Sachinidis, A	1

Reviews

2 review(s) available for bay-k-8644 and isoproterenol

Article	Year
Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists. Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Dihydropyridines; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Models, Biological; Nifedipine; Phosphorylation; Pyridines; Receptors, Adrenergic, beta	1986
Direct G-protein regulation of Ca2+ channels. Annals of the New York Academy of Sciences, 1989, Volume: 560 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Thionucleotides	1989

Article

Year

Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists.

Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:7

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Dihydropyridines; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Models, Biological; Nifedipine; Phosphorylation; Pyridines; Receptors, Adrenergic, beta

1986

Direct G-protein regulation of Ca2+ channels.

Annals of the New York Academy of Sciences, 1989, Volume: 560

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Thionucleotides

1989

Other Studies

135 other study(ies) available for bay-k-8644 and isoproterenol

Article	Year
Properties of the low threshold Ca current in single frog atrial cardiomyocytes. A comparison with the high threshold Ca current. The Journal of general physiology, 1992, Volume: 100, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Barium; Cadmium; Calcium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Heart Atria; Isoproterenol; Nickel; Nifedipine; Ouabain; Phenylephrine; Propranolol; Rana catesbeiana	1992
Cardiac function in rats with acute renal failure. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:12 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acute Kidney Injury; Animals; Glycerol; Heart; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Wistar	1992
Direct measurement of L-type Ca2+ window current in heart cells. Circulation research, 1992, Volume: 70, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium Channels; Dogs; Isoproterenol; Membrane Potentials; Models, Biological; Nicardipine; Nifedipine; Purkinje Fibers	1992
Cyclic AMP-dependent modulation of cardiac Ca channels expressed in Xenopus laevis oocytes. Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cyclic AMP; Electrophysiology; Female; Heart; Isoproterenol; Kinetics; Oocytes; Poly A; Protein Kinase Inhibitors; Rats; RNA; RNA, Messenger; Time Factors; Xenopus laevis	1992
Activation of beta-adrenergic receptors inhibits Ca2+ entry-mediated generation of inositol phosphates in the guinea pig myometrium, a cyclic AMP-independent event. Molecular pharmacology, 1992, Volume: 41, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aluminum; Animals; Calcium; Calcium Channels; Carbachol; Chromatography, High Pressure Liquid; Colforsin; Cyclic AMP; Drug Antagonism; Female; Fluorine; Guinea Pigs; Inositol Phosphates; Ionomycin; Isoproterenol; Myometrium; Nifedipine; Oxytocin; Pertussis Toxin; Receptors, Adrenergic, beta; Type C Phospholipases; Verapamil; Virulence Factors, Bordetella	1992
[Effects of trihexyphenidyl on slow action potentials in guinea pig papillary muscles]. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium-Transporting ATPases; Female; Guinea Pigs; Isoproterenol; Male; Papillary Muscles; Tetrodotoxin; Trihexyphenidyl	1992
Disparate effects of calcium channel blockers on pressure dependence of renin secretion and flow in the isolated perfused rat kidney. Pflugers Archiv : European journal of physiology, 1992, Volume: 421, Issue:2-3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bumetanide; Calcium Channel Blockers; Glomerular Filtration Rate; In Vitro Techniques; Isoproterenol; Kidney; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium; Verapamil	1992
The effects of P1- and muscarinic-receptor agonists upon cAMP-dependent and independent inotropic responses of guinea-pig cardiac preparations. General pharmacology, 1992, Volume: 23, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Receptors, Muscarinic; Receptors, Purinergic	1992
Beta-adrenergic regulation of a myocardial actin gene via a cyclic AMP-independent pathway. The Journal of biological chemistry, 1992, Oct-15, Volume: 267, Issue:29 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Animals, Newborn; Blotting, Northern; Bucladesine; Caffeine; Calcimycin; Cells, Cultured; Colforsin; Cyclic AMP; Enkephalins; Gene Expression Regulation; Heart; Heart Ventricles; Isoproterenol; Kinetics; Myocardium; Nifedipine; Potassium Chloride; Propranolol; Protein Precursors; Rats; Receptors, Adrenergic, beta; RNA; RNA, Messenger; Ryanodine	1992
The indirect negative inotropic effects of the P1-receptor agonist, L-phenylisopropyladenosine, in guinea-pig isolated cardiac preparations: comparison with cromakalim. Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Atrial Function, Left; Benzopyrans; Cardiotonic Agents; Colforsin; Cromakalim; Depression, Chemical; Guinea Pigs; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylisopropyladenosine; Pyrroles; Stimulation, Chemical; Time Factors	1992
Aging: inotropic effects of Bay K-8644 and nifedipine on rat cardiac muscle. European journal of pharmacology, 1992, Jun-17, Volume: 216, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Analysis of Variance; Animals; Calcium; Calcium Channels; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Rats; Rats, Inbred F344	1992
cAMP and calcium-dependent mechanisms of phospholamban phosphorylation in intact hearts. The American journal of physiology, 1990, Volume: 258, Issue:2 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphatases; Animals; Biomechanical Phenomena; Calcium; Calcium-Binding Proteins; Calmodulin; Cyclic AMP; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Osmolar Concentration; Phosphorylation; Rats; Rats, Inbred Strains	1990
Two pathways for Ca2+ channel gating differentially modulated by physiological stimuli. The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biomechanical Phenomena; Calcium Channels; Electrophysiology; Ion Channel Gating; Isoproterenol; Myocardium; Receptors, Adrenergic, beta	1990
Modulation of Ca2+ transients and contractile properties by beta-adrenoceptor stimulation in ferret ventricular muscles. The Journal of physiology, 1990, Volume: 423 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aequorin; Animals; Bupranolol; Calcium; Ferrets; In Vitro Techniques; Isoproterenol; Kinetics; Myocardial Contraction; Papillary Muscles; Receptors, Adrenergic, beta; Ryanodine	1990
Vasoactive intestinal peptide stimulates chick pineal melatonin production and interacts with other stimulatory and inhibitory agents but does not show alpha 1-adrenergic potentiation. Journal of neurochemistry, 1990, Volume: 55, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Chickens; Colforsin; Drug Interactions; Isoproterenol; Kinetics; Light; Melatonin; Nitrendipine; Norepinephrine; Phenylephrine; Pineal Gland; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide; Yohimbine	1990
Identification of cardiotonic sodium channel activators by potassium depolarization in isolated guinea-pig atria. Journal of pharmacological methods, 1990, Volume: 24, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Cardiotonic Agents; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Isoproterenol; Male; Monensin; Myocardial Contraction; Myocardium; Potassium; Sodium Channels	1990
Differential modulation of single voltage-gated calcium channels by cholinergic and adrenergic agonists in adult hippocampal neurons. Journal of neurophysiology, 1990, Volume: 64, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Calcium Channels; Female; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Male; Neurons; Parasympathomimetics; Pyramidal Tracts; Sympathomimetics	1990
Cardiac inotropic responses to calcium and forskolin are not altered by prolonged isoproterenol infusion. European journal of pharmacology, 1990, Oct-09, Volume: 187, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Drug Interactions; Heart; In Vitro Techniques; Infusions, Intravenous; Isoproterenol; Kinetics; Myocardial Contraction; Myocardium; Nifedipine; Radioligand Assay; Rats; Receptors, Adrenergic, beta	1990
Cyclic-AMP-dependent phosphorylation modulates the stereospecific activation of cardiac Ca channels by Bay K 8644. Pflugers Archiv : European journal of physiology, 1990, Volume: 417, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Drug Combinations; Electric Conductivity; Heart; Isoproterenol; Membrane Potentials; Myocardium; Phosphorylation; Rats	1990
Pharmacological evidence for two types of myocardial sarcoplasmic reticulum Ca2+ release. The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Anesthetics, Local; Animals; Caffeine; Calcium; Colforsin; Guinea Pigs; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Myocardium; Ryanodine; Sarcolemma; Sodium	1991
Beta-adrenergic receptor stimulates L-type calcium current in adult smooth muscle cells. Blood vessels, 1991, Volume: 28, Issue:1-3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channels; Cattle; Cyclic AMP; Dialysis; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Isoproterenol; Membrane Potentials; Muscle, Smooth; Protein Kinases; Receptors, Adrenergic, beta; Thionucleotides; Trachea	1991
Regulation of endothelin-mediated calcium mobilization in vascular smooth muscle cells by isoproterenol. The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Endothelins; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Kinetics; Muscle, Smooth, Vascular; Potassium; Propranolol	1991
Calcium currents in the A7r5 smooth muscle-derived cell line. Pflugers Archiv : European journal of physiology, 1990, Volume: 417, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Biological Transport; Calcium; Calcium Channels; Cell Line; Colforsin; Cytosol; Dihydropyridines; Electric Conductivity; Fluorescence; Isoproterenol; Ligands; Muscle, Smooth, Vascular; Nifedipine; Potassium	1990
Effect of positive inotropic agents on myosin isozyme population and mechanical activity of cultured rat heart myocytes. Circulation research, 1991, Volume: 68, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Bucladesine; Cardiotonic Agents; Cells, Cultured; Colforsin; Heart; Isoenzymes; Isoproterenol; Myocardial Contraction; Myocardium; Myosins; Ouabain; Phenylephrine; Prazosin; Propranolol; Rats	1991
Deuterium oxide reduces agonist and depolarization-induced contraction of rat aortic rings. Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:12 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Deuterium; Deuterium Oxide; Endothelium, Vascular; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitric Oxide; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Water	1990
Effects of 8-bromo-cyclic GMP on contraction and on inotropic response of ferret cardiac muscle. Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Ferrets; Isoproterenol; Myocardial Contraction; Papillary Muscles	1991
Sympathetic regulation of cardiac calcium current is due exclusively to cAMP-dependent phosphorylation. Nature, 1991, Jun-13, Volume: 351, Issue:6327 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cyclic AMP; GTP-Binding Proteins; Guinea Pigs; Heart; Ion Channel Gating; Isoproterenol; Myocardial Contraction; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Sympathetic Nervous System	1991
Interactions between endothelin-1 and other chronotropic agents in rat isolated atria. European journal of pharmacology, 1991, Mar-05, Volume: 194, Issue:2-3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Carbachol; Drug Interactions; Endothelins; Female; Heart; Heart Atria; Isoproterenol; Myocardial Contraction; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Sympathetic Nervous System; Time Factors; Tritium	1991
Studies on the mechanism of arterial vasodilation produced by the novel antihypertensive agent, carvedilol. Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Arteries; Azepines; Calcium Channel Blockers; Carbazoles; Carvedilol; Consciousness; Dose-Response Relationship, Drug; Hemodynamics; Isoproterenol; Male; Propanolamines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Vasoconstrictor Agents; Vasodilation	1991
Inverse regulation of calcium channels and beta-adrenergic receptors in virus-transformed human embryonal cells. General physiology and biophysics, 1991, Volume: 10, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Ca(2+) Mg(2+)-ATPase; Calcium Channels; Cell Line, Transformed; Cell Transformation, Viral; Cyclic AMP; Dihydroalprenolol; Embryo, Mammalian; Humans; Isoproterenol; Muscle, Smooth; Phenylephrine; Radioimmunoassay; Receptors, Adrenergic, beta; Simplexvirus; Trifluoperazine	1991
Parathyroid hormone and calcium: interactions in the control of renin secretion in the isolated, nonfiltering rat kidney. Endocrinology, 1991, Volume: 129, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Egtazic Acid; In Vitro Techniques; Isoproterenol; Kidney; Kinetics; Male; Parathyroid Hormone; Peptide Fragments; Perfusion; Rats; Rats, Inbred Strains; Renin; Teriparatide; Verapamil	1991
Modulation of Ca currents in isolated frog atrial cells studied with photosensitive probes. Regulation by cAMP and Ca2+: a common pathway? Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Cyclic AMP; Electric Conductivity; In Vitro Techniques; Isoproterenol; Kinetics; Myocardium; Phosphorylation; Photolysis; Rana esculenta	1991
Dopamine actions on calcium currents, potassium currents and hormone release in rat melanotrophs. The Journal of physiology, 1991, Volume: 439 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; beta-Endorphin; Calcium Channels; Dopamine Agents; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Pituitary Gland, Anterior; Potassium Channels; Rats; Rats, Inbred Strains; Secretory Rate	1991
Catecholamines stimulate the IFN-gamma-induced class II MHC expression on bovine brain capillary endothelial cells. Journal of immunology (Baltimore, Md. : 1950), 1991, Oct-15, Volume: 147, Issue:8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Capillaries; Catecholamines; Cattle; Cyclic AMP; Endothelium, Vascular; Histocompatibility Antigens Class II; Interferon-gamma; Isoproterenol; Receptors, Adrenergic, beta	1991
Regulation of calcitonin release from the 6.23 rat C-cell line by cyclic nucleotide analogues and pharmacological mediators. Experientia, 1991, Oct-15, Volume: 47, Issue:10 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcitonin; Carcinoma; Dibutyryl Cyclic GMP; Dinoprostone; Histamine; Isoproterenol; Rats; Thyroid Neoplasms; Tumor Cells, Cultured	1991
Comparison of the effects of milrinone and OPC 3911 with those of isoprenaline, forskolin and dibutyryl-cAMP in rat aorta. General pharmacology, 1991, Volume: 22, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Bucladesine; Calcium; Colforsin; In Vitro Techniques; Isoproterenol; Male; Milrinone; Phenylephrine; Phosphodiesterase Inhibitors; Potassium; Pyridones; Quinolones; Rats; Rats, Inbred Strains; Vasodilation	1991
Use-dependent decline in rat aorta sensitivity to contraction by potassium. Canadian journal of physiology and pharmacology, 1991, Volume: 69, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Aging; Animals; Aorta, Thoracic; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Potassium Chloride; Rats; Rats, Inbred Strains; Serotonin	1991
Differential inhibitory action of phorbol-12,13-dibutyrate on the positive inotropic effect of endothelin-1 and Bay K 8644 in the isolated rabbit papillary muscle. Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Electric Stimulation; Endothelins; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Phenylephrine; Phorbol 12,13-Dibutyrate; Rabbits; Signal Transduction; Stimulation, Chemical	1991
The beta-adrenergic receptor-regulated 1,4-dihydropyridine calcium channel receptor sites in coronary artery smooth muscle. Physiological research, 1991, Volume: 40, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cell Membrane; Cyclic AMP; Dihydropyridines; Dogs; Guanosine Triphosphate; Isoproterenol; Isradipine; Male; Microsomes; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta	1991
Effects of 8-bromo-cyclic GMP on slow channel mediated action potentials of 3-days-old embryonic chick ventricle. Journal of developmental physiology, 1991, Volume: 16, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Chick Embryo; Colforsin; Cyclic GMP; Heart Ventricles; Ion Channels; Isoproterenol; Ventricular Function	1991
Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology. The Journal of general physiology, 1985, Volume: 86, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Calcium; Cobalt; Dogs; Heart Atria; Ion Channels; Isoproterenol; Kinetics; Myocardium; Nifedipine; Nitrendipine; Tetrodotoxin	1985
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenocorticotropic Hormone; Animals; Azides; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Isoproterenol; Mice; Nifedipine; Nitroprusside; Pituitary Neoplasms; Sodium Azide; Stimulation, Chemical; Verapamil	1986
Inotropic effects of Ca2+ channel agonist and antagonists in neuraminidase-treated left atria of rats. British journal of pharmacology, 1986, Volume: 87, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Heart Atria; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Myocardial Contraction; N-Acetylneuraminic Acid; Neuraminidase; Nifedipine; Rats; Sialic Acids; Verapamil	1986
A novel type of cardiac calcium channel in ventricular cells. Biomedica biochimica acta, 1986, Volume: 45, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; Electric Conductivity; Guinea Pigs; In Vitro Techniques; Ion Channels; Isoproterenol; Membrane Potentials; Nifedipine; Ventricular Function	1986
Two types of calcium channels in guinea pig ventricular myocytes. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:14 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Diltiazem; Gallopamil; Guinea Pigs; Heart Ventricles; Ion Channels; Isoproterenol; Kinetics; Metals; Myocardium; Nifedipine	1986
PK 11195, an antagonist of peripheral type benzodiazepine receptors, modulates Bay K8644 sensitive but not beta- or H2-receptor sensitive voltage operated calcium channels in the guinea pig heart. Life sciences, 1986, Jul-28, Volume: 39, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Benzodiazepinones; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Isoproterenol; Isoquinolines; Male; Myocardial Contraction; Nifedipine; Papillary Muscles; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Histamine; Receptors, Histamine H2	1986
Effects of inotropic agents on isolated guinea pig heart under conditions that modify calcium pools involved in contractile activation. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cardiotonic Agents; Diltiazem; Diterpenes; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Monensin; Nifedipine; Ryanodine; Strophanthidin; Veratridine	1986
Voltage-dependent effects of YC-170, a dihydropyridine calcium channel modulator, in cardiovascular tissues. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cardiovascular System; Female; Guinea Pigs; Heart; Histamine; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Muscle, Smooth; Nifedipine; Potassium; Rabbits; Sinoatrial Node; Tetraethylammonium Compounds	1986
Selective inhibition by ethylisopropylamiloride of the positive inotropic effect evoked by low concentrations of ouabain in rat isolated ventricles. British journal of pharmacology, 1986, Volume: 89, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Ouabain; Rats; Rats, Inbred Strains	1986
Effects of a calcium channel agonist on renin release from perfused rat kidneys. Renal physiology, 1986, Volume: 9, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Ion Channels; Isoproterenol; Kidney; Male; Nifedipine; Perfusion; Rats; Rats, Inbred Strains; Renin; Verapamil	1986
[Influences of agents which affect ionic conductance on the tachycardiac effect of catecholamines: antitachycardiac effect]. Kokyu to junkan. Respiration & circulation, 1986, Volume: 34, Issue:11 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Barium Compounds; Cesium; Chlorides; Dose-Response Relationship, Drug; Electric Conductivity; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Ions; Isoproterenol; Male; Tetraethylammonium; Tetraethylammonium Compounds	1986
The effects of the cardiotonic dihydropyridine derivatives Bay k 8644 and H160/51 on post-rest adaptation of guinea-pig papillary muscles. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adaptation, Physiological; Animals; Cardiotonic Agents; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Pyridines	1986
Component of whole cell Ca current due to electrogenic Na-Ca-exchange in cardiac myocytes. The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anura; Calcium; Electric Conductivity; Electrophysiology; Ion Channels; Isoproterenol; Myocardial Contraction; Myocardium; Sodium	1987
Positive inotropic effects of acetylcholine and BAY K 8644 in embryonic chick ventricle. The American journal of physiology, 1987, Volume: 252, Issue:4 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Calcium; Carbachol; Chick Embryo; Cyclic AMP; Heart; Isoproterenol; Myocardial Contraction; Oxotremorine; Propranolol	1987
Effect of thyroid hormone on slow calcium channel function in cultured chick ventricular cells. The Journal of clinical investigation, 1987, Volume: 80, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cell Division; Cells, Cultured; Chick Embryo; Heart; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Receptors, Adrenergic, beta; Sarcolemma; Triiodothyronine; Ventricular Function	1987
Influence of BAY K-8644 on positive inotropic agents in guinea pig atrial muscle. European journal of pharmacology, 1987, Aug-04, Volume: 140, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Drug Synergism; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Methoxamine; Myocardial Contraction; Stimulation, Chemical; Strophanthidin	1987
A G protein directly regulates mammalian cardiac calcium channels. Science (New York, N.Y.), 1987, Nov-27, Volume: 238, Issue:4831 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Leupeptins; Membrane Potentials; Phosphorylation; Thionucleotides; Ventricular Function	1987
Adrenergic-cholinergic interactions in left atria. II. Comparison of the antagonism of inotropic responses to alpha- and beta-adrenoceptor stimulation and BAY K 8644 by carbachol, D-600, and nifedipine. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:10 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Chloride; Carbachol; Gallopamil; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rabbits	1987
Effect of thyroid status on beta-adrenoceptors and calcium channels in rat cardiac and vascular tissue. Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Hyperthyroidism; In Vitro Techniques; Iodocyanopindolol; Ion Channels; Isoproterenol; Male; Muscle, Smooth, Vascular; Myocardium; Nitrendipine; Organ Size; Papillary Muscles; Pindolol; Rats; Receptors, Adrenergic, beta; Tail; Thyroid Gland; Thyroxine	1988
[Atrial natriuretic factor diminishes the contractility of the cardiac cell in culture]. Archives des maladies du coeur et des vaisseaux, 1988, Volume: 81 Spec No Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Chick Embryo; Depression, Chemical; Electric Stimulation; Isoproterenol; Kinetics; Myocardial Contraction	1988
Interaction of BAY K-8644 with effects of digoxin in the dog heart-lung preparation. European journal of pharmacology, 1988, Dec-06, Volume: 158, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Digoxin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Lung; Male	1988
Atrial natriuretic peptide decreases contractility of cultured heart cell: preliminary report. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Heart; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Rats	1988
Methylene blue selectively inhibits pulmonary vasodilator responses in cats. Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:3 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cats; Cyclic GMP; Epinephrine; Female; Isoproterenol; Male; Methylene Blue; Nitroglycerin; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Reference Values; Vasodilation	1989
Effects of Bay K 8644 on renal function and renin secretion in anesthetized rats. Life sciences, 1989, Volume: 44, Issue:25 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Glomerular Filtration Rate; Injections, Intra-Arterial; Isoproterenol; Kidney; Kidney Function Tests; Male; Rats; Rats, Inbred Strains; Renin; Secretory Rate	1989
Differential antagonism of the negative inotropic effect of gentamicin by calcium ions, Bay K 8644 and isoprenaline in canine ventricular muscle: comparison with cobalt ions. British journal of pharmacology, 1989, Volume: 96, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cobalt; Dogs; Female; Gentamicins; Heart; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Myocardial Contraction	1989
Atrial natriuretic peptide decreases contractility of cultured chick ventricular cells. Life sciences, 1989, Volume: 45, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Atrial Natriuretic Factor; Calcium; Calcium Channels; Cells, Cultured; Chick Embryo; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Isoproterenol; Myocardial Contraction	1989
Beta-adrenoceptor blocking effects of a selective beta 2-agonist, mabuterol, on the isolated, blood-perfused right atrium of the dog. British journal of pharmacology, 1989, Volume: 97, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Calcium Chloride; Clenbuterol; Dobutamine; Dogs; Ethanolamines; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Procaterol; Propanolamines	1989
Direct hormonal regulation of smooth muscle calcium current. Journal of protein chemistry, 1989, Volume: 8, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Albuterol; Animals; Calcium Channels; Catecholamines; Cattle; Cyclic AMP; GTP-Binding Proteins; Hormones; Isoproterenol; Membrane Potentials; Muscle, Smooth; Nickel; Nitrendipine; Receptors, Adrenergic, beta; Virulence Factors, Bordetella	1989
Interaction between isoproterenol and dihydropyridines in heart cells. European journal of pharmacology, 1989, Jul-18, Volume: 166, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Isoproterenol; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Time Factors	1989
New positive inotropic agent OPC-8212 modulates single Ca2+ channels in ventricular myocytes of guinea pig. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium Channels; Cardiotonic Agents; Colforsin; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Heart Ventricles; Isoproterenol; Myocardium; Phosphorylation; Pyrazines; Quinolines	1989
A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent. Circulation research, 1985, Volume: 56, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Cattle; Cells, Cultured; Electric Stimulation; Female; Guinea Pigs; Ion Channels; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Stimulation, Chemical; Strontium; Time Factors	1985
New Ca2+ agonist (Bay K 8644) enhances and induces cardiac slow action potentials. The American journal of physiology, 1984, Volume: 247, Issue:2 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Guinea Pigs; Heart; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Papillary Muscles; Sodium; Stimulation, Chemical; Tetraethylammonium Compounds	1984
Differential effects of Bay k 8644, a presumed calcium channel activator, on sinoatrial nodal and ventricular automaticity of the dog heart. Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dogs; Heart; Heart Rate; In Vitro Techniques; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Papillary Muscles; Purkinje Fibers; Sinoatrial Node	1984
L-type calcium channel activity in human atrial myocytes as influenced by 5-HT. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Aged; Calcium Channels; Child, Preschool; Cyclic AMP; Electrophysiology; Female; Heart; Humans; In Vitro Techniques; Infant; Ion Channel Gating; Isoproterenol; Kinetics; Male; Middle Aged; Myocardial Contraction; Myocardium; Phosphorylation; Serotonin	1993
Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes. Proceedings of the National Academy of Sciences of the United States of America, 1994, Sep-13, Volume: 91, Issue:19 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Calcium; Calcium Channels; Dihydropyridines; Docosahexaenoic Acids; Fatty Acids, Omega-3; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta	1994
Elevated density and altered pharmacologic properties of myocardial calcium current of the spontaneously hypertensive rat. Journal of hypertension, 1994, Volume: 12, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium; Cell Separation; Cyclic AMP; Electrophysiology; Isoproterenol; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar	1994
ATP promotes development of afterdepolarizations and triggered activity in cardiac myocytes. The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channels; Cells, Cultured; Electric Conductivity; Female; Guinea Pigs; Heart; Heart Ventricles; Isoproterenol; Male; Membrane Potentials; Potassium Channel Blockers; Quinidine; Ryanodine; Time Factors	1994
An experimental model of the production of early after depolarizations by injury current from an ischemic region. Pflugers Archiv : European journal of physiology, 1994, Volume: 428, Issue:5-6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Guinea Pigs; Isoproterenol; Myocardial Ischemia	1994
Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophysical journal, 1995, Volume: 68, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Arrhythmias, Cardiac; Biophysical Phenomena; Biophysics; Calcium; Calcium Channels; Cesium; Guinea Pigs; Heart; Humans; Ion Transport; Isoproterenol; Kinetics; Models, Cardiovascular; Potassium Channels; Sarcoplasmic Reticulum; Sodium; Ventricular Function	1995
Pharmacological study of isoproterenol and diabetic cardiomyopathies in rat right ventricular strips. Pharmacology, 1993, Volume: 46, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Cardiomyopathies; Diabetes Mellitus, Experimental; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley	1993
A dual-component positive inotropic effect of endothelin-1 in guinea pig left atria: a role of protein kinase C. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Function; Atrial Function, Left; Cardiotonic Agents; Electrophysiology; Endothelins; Enzyme Activation; Female; Guinea Pigs; Heart; Heart Atria; Hydrolysis; Isoproterenol; Male; Myocardial Contraction; Myocardium; Nifedipine; Phosphatidylinositols; Protein Kinase C; Ryanodine; Signal Transduction	1993
Mechanisms of beta-adrenergic facilitation of LTP in rat visual cortex. Neuroreport, 1993, Volume: 4, Issue:9 Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channels; In Vitro Techniques; Isoproterenol; Long-Term Potentiation; Neurons; Nifedipine; Rats; Receptors, N-Methyl-D-Aspartate; Visual Cortex	1993
Calcium entry via L-type calcium channels acts as a negative regulator of adenylyl cyclase activity and cyclic AMP levels in cardiac myocytes. Molecular pharmacology, 1993, Volume: 44, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chick Embryo; Cyclic AMP; Depression, Chemical; Down-Regulation; Drug Synergism; Heart; Isoproterenol; Kinetics; Milrinone; Myocardium; Phosphodiesterase Inhibitors; Pyridones; Pyrrolidinones; Rolipram	1993
A comparative analysis of the time course of cardiac Ca2+ current response to rapid applications of beta-adrenergic and dihydropyridine agonists. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Isoproterenol; Membrane Potentials; Rana catesbeiana; Rana esculenta; Time Factors; Ventricular Function	1993
Genistein directly inhibits L-type calcium currents but potentiates cAMP-dependent chloride currents in cardiomyocytes. Biochemical and biophysical research communications, 1996, Jun-25, Volume: 223, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Chloride Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Genistein; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isoflavones; Isoproterenol; Kinetics; Membrane Potentials	1996
Altered pharmacologic responsiveness of reduced L-type calcium currents in myocytes surviving in the infarcted heart. Journal of cardiovascular electrophysiology, 1996, Volume: 7, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Colforsin; Cyclic AMP; Dogs; Heart; Isoproterenol; Myocardial Infarction	1996
Modulating L-type calcium current affects discontinuous cardiac action potential conduction. Biophysical journal, 1996, Volume: 71, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Biophysical Phenomena; Biophysics; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Electric Conductivity; Electric Stimulation; Guinea Pigs; Heart Ventricles; Isoproterenol; Models, Cardiovascular; Myocardium; Nifedipine	1996
Effects of Bay K 8644 on L-type calcium current from newborn rat cardiomyocytes in primary culture. Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:10 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Animals, Newborn; Bucladesine; Calcium; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; Heart; Isoproterenol; Membrane Potentials; Myocardium; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Phosphorylation; Rats; Rats, Wistar	1996
Endothelin-1 inhibits L-type Ca2+ current enhanced by isoprenaline in rat atrial myocytes. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Colforsin; Cyclic AMP; Endothelin-1; Heart Atria; Isoproterenol; Myocardium; Patch-Clamp Techniques; Protein Kinase Inhibitors; Rats	1997
Modulation of myocardial economy and efficiency in mammalian failing and non-failing myocardium by calcium channel activation and beta-adrenergic stimulation. Cardiovascular research, 1996, Volume: 32, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Guinea Pigs; Heart Failure; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Oxygen Consumption; Papillary Muscles; Rats; Rats, Wistar; Stimulation, Chemical	1996
Isoproterenol mimics calcium preconditioning-induced protection against ischemia. The American journal of physiology, 1997, Volume: 272, Issue:2 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Calcium; Calcium Channel Blockers; Heart; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Protein Kinase C; Rats; Rats, Sprague-Dawley	1997
Troponin I phosphorylation in spontaneously hypertensive rat heart: effect of beta-adrenergic stimulation. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Animals; Calcium; Calcium-Binding Proteins; Cells, Cultured; Colforsin; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Enzyme Inhibitors; Heart; Heart Ventricles; Hypertension; Isoproterenol; Marine Toxins; Myocardial Contraction; Myocardium; Myosin Light Chains; Norepinephrine; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Troponin I	1997
Beta-adrenergic regulation of constitutive nitric oxide synthase in cardiac myocytes. The American journal of physiology, 1997, Volume: 273, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Animals, Newborn; Bucladesine; Calcimycin; Cells, Cultured; Dobutamine; Enzyme Induction; Guanosine Diphosphate; Heart; Interleukin-1; Isoproterenol; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Rats; Receptors, Adrenergic, beta; Terbutaline; Thionucleotides; Trifluoperazine	1997
Downstream defects in beta-adrenergic signaling and relation to myocyte contractility after cardioplegic arrest. The Journal of thoracic and cardiovascular surgery, 1998, Volume: 115, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Colforsin; Heart Arrest, Induced; Isoproterenol; Myocardial Contraction; Receptors, Adrenergic, beta; Signal Transduction; Swine; Time Factors; Ventricular Dysfunction, Left	1998
Ovariectomy and estrogen-induced alterations in myocardial contractility in female rabbits: role of the L-type calcium channel. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Diethylstilbestrol; Estradiol; Female; Isoproterenol; Myocardial Contraction; Nitrendipine; Ovariectomy; Papillary Muscles; Rabbits; Time Factors	1998
Ceramide selectively inhibits calcium-mediated potentiation of beta-adrenergic-stimulated cyclic nucleotide accumulation in rat pinealocytes. Biochemical and biophysical research communications, 1998, Mar-06, Volume: 244, Issue:1 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Calcium; Ceramides; Cyclic AMP; Cyclic GMP; Drug Synergism; Genistein; Isoproterenol; Male; Meperidine; Phenylephrine; Pineal Gland; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate	1998
Myorelaxant activity of 2-t-butyl-4-methoxyphenol (BHA) in guinea pig gastric fundus. European journal of pharmacology, 1998, Oct-30, Volume: 360, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Antioxidants; Barium; Butylated Hydroxyanisole; Calcium Channel Agonists; Cardiotonic Agents; Cyclic AMP; Cyclic GMP; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Indoles; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Nifedipine; Nitroprusside; Tetraethylammonium; Vasodilator Agents	1998
Effects of low temperature on the chronotropic and inotropic responses to zatebradine, E-4031 and verapamil in isolated perfused dog atria. Japanese journal of pharmacology, 1998, Volume: 78, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Calcium Channel Agonists; Cardiovascular Agents; Cold Temperature; Dogs; Dose-Response Relationship, Drug; Heart Atria; Hypothermia, Induced; In Vitro Techniques; Isoproterenol; Myocardial Contraction; Perfusion; Piperidines; Pyridines; Verapamil	1998
Modulation of iron uptake in heart by L-type Ca2+ channel modifiers: possible implications in iron overload. Circulation research, 1999, Jun-11, Volume: 84, Issue:11 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Heart; In Vitro Techniques; Iron; Isoproterenol; Male; Myocardium; Nifedipine; Patch-Clamp Techniques; Permeability; Rats; Rats, Sprague-Dawley	1999
Role of ATP-dependent K(+) channels in the electrical excitability of early embryonic stem cell-derived cardiomyocytes. Journal of cell science, 1999, Volume: 112 ( Pt 17) Topics: 2,4-Dinitrophenol; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Calcium Channel Agonists; Cardiotonic Agents; Cell Differentiation; Charybdotoxin; Cromakalim; Enzyme Inhibitors; Glyburide; Isoproterenol; KATP Channels; Membrane Potentials; Mice; Myocardial Contraction; Myocardium; Organoids; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Stem Cells; Thapsigargin	1999
Changes of cardiac calcium homeostasis in spontaneously hypertensive rats. Journal of autonomic pharmacology, 1999, Volume: 19, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Heart Ventricles; Homeostasis; Hypertension; In Vitro Techniques; Isoproterenol; Male; Mibefradil; Myocardial Contraction; Myocardium; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine	1999
Sequential changes in autonomic regulation of cardiac myocytes after in vivo endotoxin injection in rat. American journal of respiratory and critical care medicine, 1999, Volume: 160, Issue:4 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adenylyl Cyclases; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Autonomic Nervous System; Calcium Channel Agonists; Calcium Channels, L-Type; Colforsin; Diterpenes; Electrophysiology; Endotoxemia; Endotoxins; Enzyme Activators; Escherichia coli; Heart; Hemodynamics; In Vitro Techniques; Injections, Intravenous; Isoproterenol; Male; Myocardium; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Rats; Sepsis	1999
Ceramide inhibits L-type calcium channel currents in rat pinealocytes. Endocrinology, 1999, Volume: 140, Issue:12 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Ceramides; Drug Synergism; Enzyme Inhibitors; Glucosyltransferases; Interleukin-1; Isoproterenol; Male; Norepinephrine; Nucleotides, Cyclic; Patch-Clamp Techniques; Phenols; Pineal Gland; Potassium Chloride; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase	1999
Induction of tissue plasminogen activator secretion from rat heart microvascular cells by fM 1,25(OH)(2)D(3). American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitriol; Calcium; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; Coronary Vessels; Female; Humans; Isoproterenol; Microcirculation; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Thapsigargin; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator	2000
Sarcoplasmic reticulum Ca content, sarcolemmal Ca influx and the genesis of arrhythmias in isolated guinea-pig cardiomyocytes. Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Cells, Cultured; Enzyme Inhibitors; Guinea Pigs; Heart; Ion Transport; Isoproterenol; Membrane Potentials; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Thapsigargin	2000
Voltage-dependent calcium channels in ventricular cells of rainbow trout: effect of temperature changes in vitro. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adaptation, Physiological; Animals; Barium; Body Temperature; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiotonic Agents; Cold Temperature; Colforsin; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Isoproterenol; Membrane Potentials; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Nifedipine; Oncorhynchus mykiss; Patch-Clamp Techniques; Pyrroles; Tetrodotoxin	2000
Effects of temperature and calcium availability on ventricular myocardium from rainbow trout. American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Body Temperature; Cadmium; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Stimulants; Cold Temperature; Heart Ventricles; Isometric Contraction; Isoproterenol; Myocardial Contraction; Myocardium; Nicardipine; Oncorhynchus mykiss; Oxygen Consumption; Patch-Clamp Techniques; Ryanodine; Sarcolemma; Ventricular Function	2000
Cardiac excitation-contraction coupling in the portal hypertensive rat. American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Cholera Toxin; Disease Models, Animal; Down-Regulation; Extracellular Space; GTP-Binding Protein alpha Subunits, Gs; Hypertension, Portal; Isoproterenol; Isradipine; Ligation; Muscle Contraction; Myocardial Contraction; Myofibrils; Papillary Muscles; Pertussis Toxin; Portal Vein; Rats; Receptors, Adrenergic, beta; Sarcoplasmic Reticulum; Sodium; Tritium; Ventricular Function; Virulence Factors, Bordetella	2000
The regulation of L-type Ca2+ currents in rat cardiac myocytes. Membrane & cell biology, 2000, Volume: 14, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Cells, Cultured; Electric Conductivity; Electrophysiology; Isoproterenol; Isoquinolines; Kinetics; Myocardium; Phosphorylation; Rats	2000
Phosphorylation of phospholamban at threonine-17 in the absence and presence of beta-adrenergic stimulation in neonatal rat cardiomyocytes. Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:12 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Animals, Newborn; Blotting, Western; Calcium; Calcium Channel Agonists; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ionophores; Isoproterenol; Myocardium; Okadaic Acid; Phosphorylation; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Serine; Signal Transduction; Thapsigargin; Threonine; Time Factors	2000
L-type calcium currents in atrial myocytes from patients with persistent and non-persistent atrial fibrillation. Basic research in cardiology, 2001, Volume: 96, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Aged; Atrial Fibrillation; Calcium Channel Agonists; Calcium Channels, L-Type; Cardiotonic Agents; Electrophysiology; Female; Heart Atria; Humans; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Middle Aged; Muscle Fibers, Skeletal; Myocardium; Recurrence	2001
Phase I and phase II of short-term mechanical restitution in perfused rat left ventricles. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Benzylamines; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Enzyme Inhibitors; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Perfusion; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Sulfonamides; Systole; Thapsigargin; Time Factors; Vasodilation; Ventricular Function, Left	2002
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil	2002
L-type Ca2+ channels gaining respect in heart failure. Circulation research, 2002, Sep-20, Volume: 91, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Bucladesine; Calcium Channel Agonists; Calcium Channels, L-Type; Heart Failure; Heart Ventricles; Humans; Isoproterenol; Membrane Potentials	2002
L-type Ca2+ channel density and regulation are altered in failing human ventricular myocytes and recover after support with mechanical assist devices. Circulation research, 2002, Sep-20, Volume: 91, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Bucladesine; Calcium Channel Agonists; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Heart Failure; Heart Ventricles; Heart-Assist Devices; Humans; Isoproterenol; Membrane Potentials; Middle Aged; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2	2002
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells. Pflugers Archiv : European journal of physiology, 2003, Volume: 446, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction	2003
Electrophysiologic effects of capsaicin on pacemaker cells in sinoatrial nodes of rabbits. Acta pharmacologica Sinica, 2003, Volume: 24, Issue:8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Capsaicin; Cell Separation; Female; Isoproterenol; Male; Myocytes, Cardiac; Rabbits; Sinoatrial Node	2003
Increased cAMP as a positive inotropic factor for mammalian skeletal muscle in vitro. Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:10 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Bucladesine; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cyclic AMP; Dantrolene; Diltiazem; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Mice; Muscle Relaxants, Central; Muscle, Skeletal; Sarcolemma; Sarcoplasmic Reticulum; Time Factors	2003
Defective calcium handling in cardiomyocytes isolated from hearts subjected to ischemia-reperfusion. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 288, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Agonists; Catalase; Cell Survival; Hydrogen Peroxide; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoproterenol; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidants; Oxidative Stress; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Superoxide Dismutase; Ventricular Pressure	2005
Dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) enhances triggered afterdepolarizations in rat ventricular myocytes. Cardiovascular toxicology, 2006, Volume: 6, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Cell Separation; Female; Heart Ventricles; In Vitro Techniques; Isoproterenol; Myocytes, Cardiac; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Ventricular Function	2006
Cholesterol depletion modulates basal L-type Ca2+ current and abolishes its -adrenergic enhancement in ventricular myocytes. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; beta-Cyclodextrins; Calcium Channel Agonists; Calcium Channels, L-Type; Calcium Signaling; Cholesterol; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic CMP; Dose-Response Relationship, Drug; Enzyme Activators; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Microdomains; Membrane Potentials; Myocytes, Cardiac; Rabbits; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Time Factors	2008
Negative regulation of beta-adrenergic function by hydrogen sulphide in the rat hearts. Journal of molecular and cellular cardiology, 2008, Volume: 44, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Calcium Signaling; Colforsin; Cyclic AMP; Electric Stimulation; Hydrogen Sulfide; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta	2008
Reduced effects of BAY K 8644 on L-type Ca2+ current in failing human cardiac myocytes are related to abnormal adrenergic regulation. American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenergic beta-Agonists; Bucladesine; Calcium Channel Agonists; Calcium Channels, L-Type; Cardiotonic Agents; Catecholamines; Drug Resistance; Heart Failure; Heart Ventricles; Heart-Assist Devices; Humans; Isoproterenol; Membrane Potentials; Myocardial Contraction; Myocytes, Cardiac; Phosphorylation	2008
In-vitro recording of adult zebrafish heart electrocardiogram - a platform for pharmacological testing. Clinica chimica acta; international journal of clinical chemistry, 2011, Oct-09, Volume: 412, Issue:21-22 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Isoproterenol; Quinidine; Zebrafish	2011
Aqueous fraction from Costus spiralis (Jacq.) Roscoe leaf reduces contractility by impairing the calcium inward current in the mammalian myocardium. Journal of ethnopharmacology, 2011, Nov-18, Volume: 138, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels, L-Type; Costus; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Patch-Clamp Techniques; Plant Extracts	2011
Chronic receptor-mediated activation of Gi/o proteins alters basal t-tubular and sarcolemmal L-type Ca²⁺ channel activity through phosphatases in heart failure. American journal of physiology. Heart and circulatory physiology, 2012, Apr-15, Volume: 302, Issue:8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Algorithms; Animals; Blood Pressure; Calcium Channel Agonists; Calcium Channels, L-Type; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Failure; Heart Rate; Isoproterenol; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Microtubules; Myocardium; Myocytes, Cardiac; Patch-Clamp Techniques; Pertussis Toxin; Phosphoprotein Phosphatases; Receptors, G-Protein-Coupled; Sarcolemma; Ultrasonography	2012
Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers. Biophysical journal, 2012, Jun-20, Volume: 102, Issue:12 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channels, L-Type; Electric Conductivity; Heart Ventricles; Isoproterenol; Models, Biological; Myocytes, Cardiac; Rats	2012
Increased intracellular magnesium attenuates β-adrenergic stimulation of the cardiac Ca(V)1.2 channel. The Journal of general physiology, 2013, Volume: 141, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Female; Isoproterenol; Magnesium; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Signal Transduction	2013
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium. British journal of pharmacology, 2013, Volume: 170, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium-Binding Proteins; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Heart Failure; Isoproterenol; Male; Mice; Mice, Knockout; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, C-Type; Phosphorylation; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Thionucleotides; Troponin I	2013
Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice. Circulation research, 2013, Aug-16, Volume: 113, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cells, Cultured; Disease Models, Animal; Electrocardiography; Hydroquinones; Isoproterenol; Lithium Chloride; Mice; Mice, Knockout; Mutation, Missense; Myocytes, Cardiac; Patch-Clamp Techniques; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tachycardia, Ventricular; Ultrasonography	2013
Cardiomyocyte sensor responsive to changes in physical and chemical environments. Journal of biomechanics, 2014, Jan-22, Volume: 47, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cells, Cultured; Digoxin; Down-Regulation; Isoproterenol; Myocardial Contraction; Myocytes, Cardiac; Rats; Up-Regulation	2014
Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes. Pflugers Archiv : European journal of physiology, 2015, Volume: 467, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Chromans; Dogs; Feedback, Physiological; Female; Heart Ventricles; Ion Channels; Ion Transport; Isoproterenol; Lidocaine; Male; Myocytes, Cardiac; Nisoldipine; Phenethylamines; Potassium Channel Blockers; Sulfonamides; Tetrodotoxin; Veratridine	2015
H2S induces vasoconstriction of rat cerebral arteries via cAMP/adenylyl cyclase pathway. Toxicology and applied pharmacology, 2015, Dec-15, Volume: 289, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Cerebral Arteries; Colforsin; Cyclic AMP; Endothelium; Hydrogen Sulfide; Isoproterenol; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Sulfides; Vasoconstriction	2015
Galectin-1 attenuates cardiomyocyte hypertrophy through splice-variant specific modulation of Ca Biochimica et biophysica acta. Molecular basis of disease, 2019, Volume: 1865, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium; Calcium Channels, L-Type; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Disease Models, Animal; Galectin 1; HEK293 Cells; Histone Deacetylases; Humans; Isoproterenol; Membrane Proteins; Myocytes, Cardiac; Phosphorylation; Rats; RNA Splicing	2019
Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes. Cells, 2019, 04-14, Volume: 8, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acceleration; Gravity, Altered; Humans; Hypergravity; Induced Pluripotent Stem Cells; Isoproterenol; Myocytes, Cardiac; Nifedipine; Space Flight; Weightlessness	2019