bay-k-8644 and indomethacin

bay-k-8644 has been researched along with indomethacin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's9 (52.94)18.2507
2000's3 (17.65)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Finkel, MS; Hartsell, TL; Oddis, CV; Romeo, RC1
Alabadí, JA; Alborch, E; Miranda, FJ; Salom, JB; Torregrosa, G1
Bhattacharya, J; Bhattacharya, S1
Advenier, C; Lagente, V; Naline, E; Puybasset, L; Sarria, B1
Christ, GJ; Maayani, S; Melman, A; Valcic, M1
Advenier, C; Cortijo, J; Esplugues, J; Morcillo, E; Naline, E; Sarriá, B1
Del Bianco, E; Geppetti, P; Maggi, CA; Patacchini, R; Santicioli, P; Tramontana, M1
MacLennan, SJ; McGrath, JC; Whittle, MJ1
Conlon, JM; Katsoulis, S1
D'Orleans-Juste, P; de Nucci, G; Finet, M; Vane, JR1
Orth, DN; Won, JG1
Brito, G; Bustamante, S; Morales, MA; Paeile, C; Ponce, H; Silva, A1
Heinemann, A; Holzer, P; Peskar, BA; Schuligoi, R; Shahbazian, A1
Keum, EM; Kim, SC; Lee, MY; Myung, SC; Park, SY1
Chang, IH; Han, JH; Kim, HJ; Kim, W; Lee, MY; Lee, SY; Myung, SC1

Other Studies

17 other study(ies) available for bay-k-8644 and indomethacin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Bay K 8644 is a negative inotrope in the presence of arachidonic acid but not eicosapentaenoic acid.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Caffeic Acids; Cricetinae; Depression, Chemical; Drug Interactions; Eicosapentaenoic Acid; In Vitro Techniques; Indomethacin; Lipoxygenase; Male; Mesocricetus; Myocardial Contraction; Papillary Muscles; Prostaglandin-Endoperoxide Synthases; Radioligand Assay

1992
Comparison of the contractile effects of endothelin-1 and sarafotoxin S6b in goat isolated cerebral arteries.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Female; Goats; Indomethacin; Nicardipine; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms

1992
Segmental vascular responses to voltage-gated calcium channel potentiation in rat lung.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 73, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Blood Pressure; Calcium; Calcium Channels; Histamine; In Vitro Techniques; Indomethacin; Ion Channel Gating; Lung; omega-N-Methylarginine; Potassium; Rats; Rats, Sprague-Dawley; Vasoconstriction

1992
Contractile activity of three endothelins (ET-1, ET-2 and ET-3) on the human isolated bronchus.
    British journal of pharmacology, 1990, Volume: 100, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Bronchi; Calcium Channel Blockers; Endothelins; Female; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Nicardipine; Peptides

1990
Pharmacological studies of human erectile tissue: characteristics of spontaneous contractions and alterations in alpha-adrenoceptor responsiveness with age and disease in isolated tissues.
    British journal of pharmacology, 1990, Volume: 101, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Aged; Aged, 80 and over; Aging; Diabetes Complications; Erectile Dysfunction; Humans; In Vitro Techniques; Indomethacin; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Penile Erection; Penis; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha

1990
Calcium dependence of the contraction produced by endothelin (ET-1) in isolated guinea-pig trachea.
    European journal of pharmacology, 1990, Oct-23, Volume: 187, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Endothelins; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Trachea

1990
Low pH-induced release of calcitonin gene-related peptide from capsaicin-sensitive sensory nerves: mechanism of action and biological response.
    Neuroscience, 1991, Volume: 41, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acids; Animals; Calcitonin Gene-Related Peptide; Calcium Channels; Capsaicin; Guinea Pigs; Hydrogen-Ion Concentration; Indomethacin; Isoquinolines; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Neurosecretion; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Piperazines; Potassium; Ruthenium Red; Tetrodotoxin; Urinary Bladder

1991
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
    Prostaglandins, 1988, Volume: 36, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aspirin; Calcium; Female; Flurbiprofen; Humans; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Nitroprusside; Oxygen; Partial Pressure; Pregnancy; Propionates; Reference Values; Umbilical Arteries

1988
Calcitonin gene-related peptides relax guinea pig and rat gastric smooth muscle.
    European journal of pharmacology, 1989, Mar-14, Volume: 162, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcitonin Gene-Related Peptide; Female; Guinea Pigs; Humans; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; Neuropeptides; Rats; Rats, Inbred Strains; Stomach; Verapamil

1989
Pharmacology of endothelin-1 in isolated vessels: effect of nicardipine, methylene blue, hemoglobin, and gossypol.
    Journal of cardiovascular pharmacology, 1989, Volume: 13 Suppl 5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium Channels; Endothelins; Gossypol; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Peptides; Rabbits; Rats; Rats, Inbred Strains; Veins

1989
Role of lipoxygenase metabolites of arachidonic acid in the regulation of adrenocorticotropin secretion by perifused rat anterior pituitary cells.
    Endocrinology, 1994, Volume: 135, Issue:4

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arginine Vasopressin; Calcium; Cells, Cultured; Corticotropin-Releasing Hormone; Diglycerides; Eicosanoids; Hydroxyeicosatetraenoic Acids; Indomethacin; Ionomycin; Lipoxygenase; Male; Masoprocol; Pituitary Gland, Anterior; Potassium Chloride; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Tritium

1994
Vasorelaxant effect of the analgesic clonixin on rat aorta.
    General pharmacology, 1995, Volume: 26, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Animals; Aorta, Thoracic; Blood Pressure; Calcium; Clonixin; Drug Interactions; Female; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium Chloride; Rats; Rats, Sprague-Dawley; Verapamil

1995
Disturbance of peristalsis in the guinea-pig isolated small intestine by indomethacin, but not cyclo-oxygenase isoform-selective inhibitors.
    British journal of pharmacology, 2001, Volume: 132, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Agonists; Calcium Channels; Cyclic AMP; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Guinea Pigs; Indomethacin; Intestine, Small; Isoenzymes; Lipoxygenase Inhibitors; Male; Peristalsis; Potassium Channels; Prostaglandin-Endoperoxide Synthases; Receptors, Thromboxane; RNA, Messenger; Vasoconstrictor Agents

2001
Vasomotor action of insulin on the rabbit normal cavernous smooth muscle.
    European journal of pharmacology, 2006, Apr-24, Volume: 536, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Animals; Calcium Channels; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Insulin; Male; Membrane Potentials; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Penis; Potassium Channel Blockers; Potassium Channels; Prostaglandins; Prostaglandins H; Rabbits; Tetraethylammonium; Vasoconstrictor Agents

2006
Effect of low concentrations of hydrogen peroxide on the contractile responses of rat detrusor smooth muscle strips.
    European journal of pharmacology, 2010, Jul-25, Volume: 638, Issue:1-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Amides; Animals; Calcium; Dose-Response Relationship, Drug; Drug Synergism; Hydrogen Peroxide; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Phenylephrine; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors; Urinary Bladder; Verapamil; Vitamin E

2010