bay-k-8644 and diltiazem

bay-k-8644 has been researched along with diltiazem in 93 studies

Research

Studies (93)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (44.09)	18.7374
1990's	40 (43.01)	18.2507
2000's	10 (10.75)	29.6817
2010's	2 (2.15)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Laorden, ML; Micol, JA	1
De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR	1
Abiko, Y; Ichihara, K; Nasa, Y; Yoshida, R	1
Finkel, MS; Oddis, CV; Romeo, RC; Salama, G	1
Raij, L; Shultz, PJ	1
Sayeed, MM; Westfall, MV	1
Datta, HK; MacIntyre, I; Zaidi, M	1
Fox, R; Markham, A; Morgan, R	1
Adeyemo, OM; Feuerstein, G; Shapira, S	1
Naitoh, T; Sugimoto, T; Toyo-Oka, T	1
Baydoun, AR; Markham, A; Morgan, RM; Sweetman, AJ	1
Ballesta, JJ; Garcia, AG; Gutierrez, LM; Hidalgo, MJ; Palmero, M; Reig, JA; Viniegra, S	1
Högestätt, ED; Skärby, TV	1
Tan, SY; Tepperman, BL; Whittle, BJ	1
Baeyens, JM; Barrios, M	2
Rampe, D; Triggle, DJ; Zheng, W	1
Addicks, K; Fricke, U; Gielen, W; Klaus, W; Sarram, M; Werner, G	1
Langer, SZ; Schoemaker, H	1
Iijima, T	1
Glossmann, H; Goll, A; Moosburger, K; Striessnig, J	1
Hattori, Y; Hazama, S; Kanno, M; Nakao, Y	1
Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK	1
Mitra, R; Morad, M	1
Conte-Camerino, D; De Luca, A; Lograno, M; Persichella, M	1
Donoso, MV; Huidobro-Toro, JP; Kullak, A	1
Aoki, K; Asano, M; Matsuda, T	1
Akera, T; Ng, YC; Temma, K	1
Hosey, MM; Maan, AC; Ptasienski, J	1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A	1
Cornwell, MM; Gottesman, MM; Pastan, I	1
Kavaliers, M	2
Janis, RA; Sarmiento, JG; Shrikhande, AV; Triggle, DJ	1
Carpenter, CL; Greenberg, DA; Messing, RO	1
Ousterhout, JM; Sperelakis, N	1
Ohshika, H; Takemura, H	1
Abraham, S; Amitai, G; Oz, N; Weissman, BA	1
Furukawa, T; Katsuragi, T; Usune, S	1
Carboni, E; Wojcik, WJ	1
Ishii, K; Sato, Y; Taira, N	1
Kavaliers, M; Ossenkopp, KP	1
Ogawa, N; Ono, H; Yokota, S	1
Boddeke, HW; Heynis, JB; van Zwieten, PA; Wilffert, B	1
Auguet, M; Braquet, P; Chabrier, PE; Clostre, F; Delaflotte, S; Pirotzky, E	1
Barnes, S; Davies, JA	1
Poder, T; Rampe, D; Schilling, WP; Zhao, ZY	1
Donowitz, M; Homaidan, FR; Sharp, GW; Weiland, GA	1
Hernández, J; Pérez, D; Ruiz, F	1
Grover, GJ; Moreland, S; Parham, CS; Sleph, PG	1
Bertaccini, G; Coruzzi, G; Poli, E	1
Chang, CC; Chiou, LC; Hong, SJ; Huang, CY; Hwang, LL	1
Belin, C; Carriot, T; Doble, A; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Renault, C; Uzan, A	1
Doyle, VM; Rüegg, UT	1
Ishii, K; Taira, N; Yanagisawa, T	1
Fischli, W; Hengartner, U; Holck, M	1
Freedman, SB; Miller, DM; Miller, RJ; Tindall, DR	1
Freedman, SB; Miller, RJ	1
Abbe, R; Appel, SH; Bostwick, JR	1
Dakshinamurti, K; Lal, KJ	1
Baeyens, JM; Barrios, M; Robles, I	1
Little, HJ; Watson, WP	1
Costantin, JL; Crawford, GD; Neely, A; Olcese, R; Palade, P; Perez-Reyes, E; Qin, N; Schneider, T; Wei, X; Zhou, J	1
García, AG; Guantes, JM; Michelena, P; Montiel, C; Uceda, G	1
Arneric, SP; Donnelly-Roberts, DL; Sullivan, JP	1
Farrugia, G; Rae, JL; Rich, A; Sarr, MG; Szurszewski, JH	1
Loutzenhiser, R; Reslerova, M	1
Denborough, MA; Foster, PS	1
Akimoto, T; Ichida, S; Kishino, H; Matsuda, N; Nakazaki, S; Wada, T	1
Alfaro, MJ; Colado, MI; Del Val, V; Lopez, F; Martin, MI	1
Löscher, W; Richter, A	1
Barrús, MT; Marín, J; Reviriego, J	1
Nebe, J; Neugebauer, V; Rümenapp, P; Schaible, HG; Vanegas, H	1
Bardisa, L; Barra, E; Barrios, M; Demetrio, C; Martín, N; Pantoja, C; Sepúlveda, MJ; Valenzuela, J	1
Alvarez, LJ; Candia, OA; Zamudio, AC	1
Beyreuther, K; Masters, CL; Sáez-Valero, J; Sberna, G; Small, DH	1
Gjini, V; Korth, M; Schmitt, C; Schömig, A; Schreieck, J; Weyerbrock, S	1
Koizumi, S; Moriyama, Y; Ogura, A; Yamada, H; Yamaguchi, A	1
Eatman, D; Rutecki, GW; Stallone, JN; Whittier, FC	1
Campbell, DB; Hess, EJ	1
Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S	1
Carmines, PK; Hall, DA; Sansom, SC	1
Ikeda, M; Ikeda, U; Minota, S; Ohki, R; Shimada, K; Shimpo, M; Takahashi, M; Yamamoto, K	1
Ahn, JS; Cho, KW; Cui, X; Kim, SH; Kim, SZ; Lee, HS; Park, YK; Seul, KH; Wen, JF	1
Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L	1
Flameng, W; Macianskiene, R; Moccia, F; Mubagwa, K; Sipido, KR	1
Barclay, JK; Murrant, CL; Reading, SA	1
Baharvand, H; Heidari, MH; Hosseini, A; Piryaei, A; Rohani, R; Taei, A	1
Minarovic, I; Zahradník, I; Zahradníková, A	1
Du, L; Shen, J; Wang, W; Wang, Z; Xing, D; Yip, S	1
Haruki, A; Himi, T; Kosaka, J; Obata, M; Sekiguchi-Tonosaki, M	1
Berkowitz, BA; Berri, AM; Dernay, K; Farrell, B; Graffice, E; Kern, TS; Lee, H; Podolsky, RH; Roberts, R; Shafie-Khorassani, F; Trepanier, C	1
Gao, S; Huang, G; Lei, J; Wu, J; Wu, Q; Yan, N; Yan, Z; Zhao, Y	1

Reviews

1 review(s) available for bay-k-8644 and diltiazem

Article	Year
[Calcium ion channels in cardiac cell membranes]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Anura; Calcium; Calcium Channel Blockers; Cardiac Glycosides; Cardiotonic Agents; Catecholamines; Cats; Cattle; Diltiazem; Gallopamil; Guinea Pigs; Heart; Humans; In Vitro Techniques; Ion Channels; Membrane Potentials; Models, Cardiovascular; Myocardium; Nifedipine; Purkinje Fibers	1985

Article

Year

[Calcium ion channels in cardiac cell membranes].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:6

Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Anura; Calcium; Calcium Channel Blockers; Cardiac Glycosides; Cardiotonic Agents; Catecholamines; Cats; Cattle; Diltiazem; Gallopamil; Guinea Pigs; Heart; Humans; In Vitro Techniques; Ion Channels; Membrane Potentials; Models, Cardiovascular; Myocardium; Nifedipine; Purkinje Fibers

1985

Other Studies

92 other study(ies) available for bay-k-8644 and diltiazem

Article	Year
Interaction of U-50,488H with calcium channel agonists and antagonists in different cardiac tissues. Journal of autonomic pharmacology, 1992, Volume: 12, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Antihypertensive Agents; Benzomorphans; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Atria; Heart Rate; Male; Myocardial Contraction; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa	1992
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice. General pharmacology, 1992, Volume: 23, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil	1992
Positive inotropic and negative chronotropic effects of (-)-cis-diltiazem in rat isolated atria. British journal of pharmacology, 1992, Volume: 105, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Atenolol; Calcium; Diltiazem; Endothelium, Vascular; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Potassium Chloride; Quinazolines; Rats; Rats, Inbred Strains; Stereoisomerism; Verapamil	1992
Inotropic effects of calcium antagonists in the cardiomyopathic Syrian hamster. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Cardiomyopathies; Cricetinae; Depression, Chemical; Diltiazem; Gallopamil; Mesocricetus; Myocardial Contraction; Nifedipine; Stimulation, Chemical; Verapamil	1992
Inhibition of human mesangial cell proliferation by calcium channel blockers. Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:2 Suppl Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channel Blockers; Cell Division; Cells, Cultured; Dantrolene; Diltiazem; Glomerular Mesangium; Humans; Nifedipine; Platelet-Derived Growth Factor; Thrombin; Thymidine; Verapamil	1990
Effect of Ca2(+)-channel agonists and antagonists on skeletal muscle sugar transport. The American journal of physiology, 1990, Volume: 258, Issue:2 Pt 2 Topics: 3-O-Methylglucose; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biological Transport; Calcium Channel Agonists; Calcium Channel Blockers; Carbohydrate Metabolism; Diltiazem; Insulin; Male; Methylglucosides; Muscles; Nifedipine; Rats; Rats, Inbred Strains	1990
Intracellular calcium in the control of osteoclast function. I. Voltage-insensitivity and lack of effects of nifedipine, BAYK8644 and diltiazem. Biochemical and biophysical research communications, 1990, Feb-28, Volume: 167, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bone Resorption; Calcium; Diltiazem; Membrane Potentials; Nifedipine; Osteoclasts; Rats; Rats, Inbred Strains	1990
Effect of calcium-modifying drugs on glutamate dehydrogenase and isocitrate dehydrogenase activity. Biochemical Society transactions, 1990, Volume: 18, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Diltiazem; Glutamate Dehydrogenase; Homeostasis; In Vitro Techniques; Isocitrate Dehydrogenase; Kinetics; Mitochondria, Heart; Rats; Verapamil	1990
Integrated autonomic and behavioral responses to L/N Ca2(+)-channel blocker omega-conotoxin in conscious rats. The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Autonomic Nervous System; Behavior, Animal; Blood Chemical Analysis; Body Temperature; Calcium Channel Blockers; Catecholamines; Diltiazem; Hemodynamics; Injections, Intraventricular; Male; Motor Activity; Nervous System; omega-Conotoxins; Peptides, Cyclic; Rats; Rats, Inbred Strains	1990
An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system. Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Endothelins; Heart; Isradipine; Kinetics; Liposomes; Microsomes; Oxadiazoles; Proteolipids; Sarcolemma; Swine; Verapamil	1990
Bay K 8644, modifier of calcium transport and energy metabolism in rat heart mitochondria: a new intracellular site of action. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Diphosphate; Animals; Biological Transport, Active; Calcium; Diltiazem; Energy Metabolism; Female; Glutamates; In Vitro Techniques; Malates; Mitochondria, Heart; NAD; Nitrendipine; Oxidation-Reduction; Oxygen Consumption; Rats; Ruthenium Red; Verapamil	1990
Separate [3H]-nitrendipine binding sites in mitochondria and plasma membranes of bovine adrenal medulla. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channels; Cattle; Cell Membrane; Chromaffin System; Diltiazem; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mitochondria; Nitrendipine; Receptors, Nicotinic; Stereoisomerism; Subcellular Fractions; Verapamil	1990
Differential effects of calcium antagonists and Bay K 8644 on contractile responses to exogenous noradrenaline and adrenergic nerve stimulation in the rabbit ear artery. British journal of pharmacology, 1990, Volume: 101, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Arteries; Calcium; Calcium Channel Blockers; Diltiazem; Ear, External; Electric Stimulation; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Rabbits; Sympathetic Nervous System; Tetrodotoxin; Verapamil	1990
Effects of calcium-modifying agents on integrity of rabbit isolated gastric mucosal cells. The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Cell Separation; Diltiazem; Ethanol; Gastric Mucosa; In Vitro Techniques; Nifedipine; Protease Inhibitors; Rabbits; Trypan Blue; Verapamil	1991
Differential effects of L-type calcium channel blockers and stimulants on naloxone-precipitated withdrawal in mice acutely dependent on morphine. Psychopharmacology, 1991, Volume: 104, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Mice; Morphine Dependence; Naloxone; Nicardipine; Postural Balance; Substance Withdrawal Syndrome; Verapamil	1991
Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations. Molecular pharmacology, 1991, Volume: 40, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Isradipine; Male; Myocardium; Potassium; Pyrroles; Radioligand Assay; Rats; Vasoconstriction; Verapamil	1991
Sialic acid removal modulates the myocardial and vascular activity of calcium channel ligands. Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium; Calcium Channels; Cricetinae; Diltiazem; Dose-Response Relationship, Drug; Electric Stimulation; Fendiline; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; N-Acetylneuraminic Acid; Neuraminidase; Nisoldipine; Rabbits; Sialic Acids	1991
[3H]diltiazem binding to calcium channel antagonists recognition sites in rat cerebral cortex. European journal of pharmacology, 1985, May-08, Volume: 111, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Calcium Channels; Cerebral Cortex; Diltiazem; In Vitro Techniques; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Tritium	1985
Purified calcium channels have three allosterically coupled drug receptors. FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil	1986
Inotropic effects of Ca2+ channel agonist and antagonists in neuraminidase-treated left atria of rats. British journal of pharmacology, 1986, Volume: 87, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Heart Atria; In Vitro Techniques; Ion Channels; Isoproterenol; Male; Myocardial Contraction; N-Acetylneuraminic Acid; Neuraminidase; Nifedipine; Rats; Sialic Acids; Verapamil	1986
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors. The Journal of biological chemistry, 1986, Jun-25, Volume: 261, Issue:18 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil	1986
Two types of calcium channels in guinea pig ventricular myocytes. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:14 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Diltiazem; Gallopamil; Guinea Pigs; Heart Ventricles; Ion Channels; Isoproterenol; Kinetics; Metals; Myocardium; Nifedipine	1986
[Effects of a new 1,4-dihydropyridine, Bay K 8644, on smooth muscle organs isolated from the guinea pig]. Bollettino della Societa italiana di biologia sperimentale, 1986, Apr-30, Volume: 62, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Verapamil	1986
Involvement of calcium channels in the contractile activity of neurotensin but not acetylcholine: studies with calcium channel blockers and Bay K 8644 on the rat fundus. British journal of pharmacology, 1986, Volume: 88, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Gallopamil; Gastric Fundus; Ion Channels; Muscle Contraction; Neurotensin; Nifedipine; Rats; Rats, Inbred Strains	1986
Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dose-Response Relationship, Drug; Femoral Artery; Hypertension; Male; Muscle Contraction; Nifedipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1986
Effects of inotropic agents on isolated guinea pig heart under conditions that modify calcium pools involved in contractile activation. Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cardiotonic Agents; Diltiazem; Diterpenes; Female; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Monensin; Nifedipine; Ryanodine; Strophanthidin; Veratridine	1986
Influence of Mg++ on the effect of diltiazem to increase dihydropyridine binding to receptors on Ca++-channels in chick cardiac and skeletal muscle membranes. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Chickens; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Isradipine; Magnesium; Membranes; Muscles; Myocardium; Nitrendipine; Oxadiazoles; Receptors, Nicotinic	1986
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation. Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 8 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Cholic Acids; Diltiazem; Ion Channels; Isradipine; Kinetics; Macromolecular Substances; Molecular Weight; Muscles; Myocardial Contraction; Oxadiazoles; Pyridines; Pyrrolidines; Receptors, Nicotinic; Verapamil	1986
Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein. The Journal of biological chemistry, 1987, Feb-15, Volume: 262, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Carcinoma; Cell Line; Diltiazem; Drug Resistance; Glycoproteins; Humans; Nitrendipine; Quinidine; Verapamil; Vinblastine	1987
Aggression and defeat-induced opioid analgesia displayed by mice are modified by calcium channel antagonists and agonists. Neuroscience letters, 1987, Feb-10, Volume: 74, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Calcium Channel Blockers; Diltiazem; Mice; Nifedipine; Pain; Reaction Time; Verapamil	1987
[3H]BAY K 8644, a 1,4-dihydropyridine Ca++ channel activator: characteristics of binding to high and low affinity sites in cardiac membranes. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Diltiazem; Edetic Acid; Female; Heart Ventricles; Hot Temperature; Kinetics; Lipolysis; Mathematics; Membranes; Myocardium; Nitrendipine; Propylamines; Rabbits; Tiapamil Hydrochloride; Verapamil	1987
Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs. Brain research, 1987, Apr-28, Volume: 410, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cell Line; Diltiazem; Drug Interactions; Ethanol; Flunarizine; Ion Channels; Nifedipine; Verapamil	1987
Stimulatory influences of calcium channel antagonists on stress-induced opioid analgesia and locomotor activity. Brain research, 1987, Apr-07, Volume: 408, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Diltiazem; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immobilization; Mice; Mice, Inbred C57BL; Motor Activity; Naloxone; Nifedipine; Pain; Reaction Time; Stress, Physiological; Verapamil	1987
Effect of Bay K 8644 on tetraethylammonium-induced excitability of the rabbit pulmonary artery. Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Diltiazem; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Membrane Potentials; Pulmonary Artery; Rabbits; Tetraethylammonium; Tetraethylammonium Compounds; Vasoconstriction	1987
Effects of Ca2+ agonist and antagonists on cytosolic free Ca2+ concentration: studies on Ca2+ channels in rat parotid cells. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 88, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Ion Channels; Kinetics; Male; Methoxamine; Nicardipine; Parotid Gland; Potassium; Rats; Rats, Inbred Strains; Verapamil	1987
Bay K 8644-induced changes in the ECG pattern of the rat and their inhibition by antianginal drugs. British journal of pharmacology, 1987, Volume: 92, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Blood Pressure; Carotid Arteries; Diltiazem; Dose-Response Relationship, Drug; Electrocardiography; Injections, Intra-Arterial; Isoquinolines; Male; Nifedipine; Nitroglycerin; Phentolamine; Rats; Rats, Inbred Strains	1987
Interaction between Bay-K-8644 and various relaxant agents on K+-depolarized contracture of guinea pig taenia coli. General pharmacology, 1988, Volume: 19, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Colon; Dihydropyridines; Diltiazem; Ethanol; Gallopamil; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Nifedipine; Papaverine; Potassium	1988
Dihydropyridine binding sites regulate calcium influx through specific voltage-sensitive calcium channels in cerebellar granule cells. Journal of neurochemistry, 1988, Volume: 50, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Cations, Divalent; Cell Membrane; Cells, Cultured; Cerebellum; Diltiazem; Electrophysiology; Ion Channels; Neurons; Nifedipine; Nitrendipine; Potassium; Rats; Receptors, Nicotinic; Verapamil	1988
Differential antagonism by Bay K 8644 of vasodilator effects of nifedipine, diltiazem, nicorandil and nitroglycerin in dog femoral circulation. British journal of pharmacology, 1988, Volume: 93, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Femur; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Regional Blood Flow; Vasodilator Agents	1988
Magnetic fields inhibit opioid-mediated 'analgesic' behaviours of the terrestrial snail, Cepaea nemoralis. Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1988, Volume: 162, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Calcium; Diltiazem; Ion Channels; Magnetics; Morphine; Naloxone; Nifedipine; Nociceptors; Pyrrolidines; Snails; Temperature; Verapamil	1988
Different interaction of bepridil and diltiazem with BAY K 8644 in the abolition of autoregulation of renal blood flow. Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bepridil; Calcium Channel Blockers; Diltiazem; Dogs; Female; Homeostasis; Infusions, Intra-Arterial; Male; Pyrrolidines; Renal Circulation; Vascular Resistance	1988
Investigation of the mechanism of negative inotropic activity of some calcium antagonists. Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Arrhythmia Agents; Bepridil; Calcimycin; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Female; Flunarizine; Guinea Pigs; In Vitro Techniques; Lidoflazine; Male; Myocardial Contraction; Pyrrolidines; Verapamil	1988
Endothelin and Ca++ agonist Bay K 8644: different vasoconstrictive properties. Biochemical and biophysical research communications, 1988, Oct-14, Volume: 156, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Aorta, Thoracic; Calcium; Carbachol; Diltiazem; Egtazic Acid; Endothelins; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Peptides; Phenylephrine; Rats; Rats, Inbred Strains; Reference Values; Vasoconstrictor Agents	1988
The effects of calcium channel agonists and antagonists on the release of endogenous glutamate from cerebellar slices. Neuroscience letters, 1988, Sep-23, Volume: 92, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcimycin; Calcium Channel Blockers; Calcium Channels; Cerebellum; Diltiazem; Female; Glutamates; Glutamic Acid; In Vitro Techniques; Potassium; Rats; Rats, Inbred Strains; Verapamil	1988
Differential effects of calcium channel blockers and stimulants on morphine withdrawal in vitro. European journal of pharmacology, 1988, Jul-26, Volume: 152, Issue:1-2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Diltiazem; Ethanol; Female; In Vitro Techniques; Morphine; Muscle Contraction; Muscle, Smooth, Vascular; Naloxone; Rats; Rats, Inbred Strains; Stereoisomerism; Substance Withdrawal Syndrome; Verapamil	1988
Calcium channel agonist and antagonist binding in a highly enriched sarcolemma preparation obtained from canine ventricle. Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Dogs; Dose-Response Relationship, Drug; Heart Ventricles; Imines; In Vitro Techniques; Isradipine; Oxadiazoles; Sarcolemma	1989
Two calcium channels in basolateral membranes of rabbit ileal epithelial cells. The American journal of physiology, 1989, Volume: 257, Issue:1 Pt 1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Chlorides; Diltiazem; Egtazic Acid; Electric Conductivity; Epithelium; Ileum; Male; Nifedipine; Nitrendipine; Rabbits; Sodium; Verapamil	1989
The effect of diazepam on ventricular automaticity induced by a local injury. Evidence of involvement of "peripheral type" benzodiazepine receptors. The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diazepam; Diltiazem; Dose-Response Relationship, Drug; Female; Flumazenil; Heart Ventricles; Isoquinolines; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ventricular Function	1989
Anti-ischemic and vasorelaxant effects of the new benzazepine calcium channel blocker SQ 31,765. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Coronary Vessels; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Swine; Vasodilator Agents	1989
Effect of calcium-channel blockers and salbutamol on the isolated mare uterus--interaction with the calcium agonist Bay K 8644. Journal of veterinary pharmacology and therapeutics, 1989, Volume: 12, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Albuterol; Animals; Calcium Channel Blockers; Diltiazem; Drug Interactions; Female; Horses; Nifedipine; Uterine Contraction; Uterus; Verapamil	1989
Nicardipine inhibits axon conduction but causes dual changes of acetylcholine release in the mouse motor nerve. Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:12 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Axonal Transport; Axons; Chick Embryo; Diaphragm; Diltiazem; Female; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Motor Neurons; Muscle Contraction; Nicardipine; Nifedipine; Sodium Channels; Succinylcholine; Verapamil	1989
Electrophysiological and pharmacological evidence that peripheral type benzodiazepine receptors are coupled to calcium channels in the heart. Life sciences, 1985, Jan-28, Volume: 36, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Heart; Ion Channels; Isoquinolines; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Receptors, GABA-A; Tetraethylammonium Compounds; Verapamil	1985
Lack of evidence for voltage dependent calcium channels on platelets. Biochemical and biophysical research communications, 1985, Feb-28, Volume: 127, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Blood Platelets; Calcium; Diltiazem; Humans; Ion Channels; Nifedipine; Sodium; Thrombin; Time Factors	1985
Differential antagonism by Bay k 8644, a dihydropyridine calcium agonist, of the negative inotropic effects of nifedipine, verapamil, diltiazem and manganese ions in canine ventricular muscle. British journal of pharmacology, 1985, Volume: 84, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dogs; Female; Heart; In Vitro Techniques; Male; Manganese; Myocardial Contraction; Nifedipine; Verapamil	1985
Effects of temperature and allosteric modulators on [3H] nitrendipine binding: methods for detecting potential Ca2+ channel blockers. Journal of receptor research, 1984, Volume: 4, Issue:1-6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Animals; Benzothiazoles; Binding Sites; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Microsomes; Myocardium; Nifedipine; Nitrendipine; Propylamines; Temperature; Thiazoles; Tiapamil Hydrochloride; Verapamil	1984
Interactions of maitotoxin with voltage-sensitive calcium channels in cultured neuronal cells. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:14 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Diltiazem; Dose-Response Relationship, Drug; Gallopamil; Ion Channels; Marine Toxins; Neurons; Nifedipine; Nitrendipine; Oxocins; Potassium	1984
Calcium channel activation: a different type of drug action. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:17 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channel Blockers; Cell Line; Diltiazem; Gallopamil; Glioma; Hybrid Cells; Ion Channels; Kinetics; Mice; Neuroblastoma; Nifedipine; Nitrendipine; Pyridines; Rats	1984
Modulation of acetylcholine release in rat hippocampus by amino alcohols and Bay K 8644. Brain research, 1993, Nov-26, Volume: 629, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Cerebral Cortex; Choline; Corpus Striatum; Diltiazem; Dose-Response Relationship, Drug; Ethanolamine; Ethanolamines; Flunarizine; Hippocampus; In Vitro Techniques; Male; Nifedipine; Osmolar Concentration; Potassium Chloride; Propanolamines; Pyrrolidines; Rats; Rats, Inbred F344; Verapamil	1993
Calcium channels in vitamin B6 deficiency-induced hypertension. Journal of hypertension, 1993, Volume: 11, Issue:12 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Diltiazem; Hypertension; Male; Nicotinic Acids; Nifedipine; Oxadiazoles; Rats; Rats, Sprague-Dawley; Verapamil; Vitamin B 6 Deficiency	1993
Role of L-type calcium channels on yohimbine-precipitated clonidine withdrawal in vivo and in vitro. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Calcium Channels; Clonidine; Diltiazem; Dose-Response Relationship, Drug; Drug Implants; Female; Ileum; In Vitro Techniques; Isomerism; Mice; Muscle Contraction; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Verapamil; Yohimbine	1993
Effects of diltiazem in convulsive states differ from those previously reported for dihydropyridine calcium channel antagonists. Psychopharmacology, 1994, Volume: 114, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Convulsants; Diltiazem; Infusions, Intravenous; Male; Mice; Mice, Inbred Strains; Nitrendipine; Seizures	1994
Molecular analysis and functional expression of the human type E neuronal Ca2+ channel alpha 1 subunit. Receptors & channels, 1994, Volume: 2, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alternative Splicing; Amino Acid Sequence; Animals; Barium; Base Sequence; Binding Sites; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, R-Type; Cation Transport Proteins; Cloning, Molecular; Diltiazem; DNA Primers; Female; Gallopamil; Gene Expression; Genetic Variation; Humans; Kinetics; Macromolecular Substances; Membrane Potentials; Molecular Sequence Data; Neurons; Nickel; omega-Agatoxin IVA; omega-Conotoxin GVIA; Oocytes; Peptides; Polyamines; Polymerase Chain Reaction; Rabbits; Rats; Restriction Mapping; Sequence Homology, Amino Acid; Skates, Fish; Spider Venoms; Xenopus laevis	1994
Effects of Ca2+ channel antagonist subtypes on mitochondrial Ca2+ transport. European journal of pharmacology, 1995, Mar-15, Volume: 289, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Cattle; Diltiazem; Flunarizine; In Vitro Techniques; Mitochondria; Nitrendipine; Verapamil	1995
Functional modulation of human "ganglionic-like" neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists. Biochemical and biophysical research communications, 1995, Aug-15, Volume: 213, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cadmium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Humans; Isradipine; Neuroblastoma; Neurons; Nicotine; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Receptors, Nicotinic; Spider Venoms; Tumor Cells, Cultured; Verapamil	1995
Calcium currents in human and canine jejunal circular smooth muscle cells. Gastroenterology, 1995, Volume: 109, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channels; Diltiazem; Dogs; Erythromycin; Humans; In Vitro Techniques; Jejunum; Membrane Potentials; Muscle, Smooth; Nifedipine; Patch-Clamp Techniques	1995
Divergent mechanisms of ATP-sensitive K+ channel-induced vasodilation in renal afferent and efferent arterioles. Evidence of L-type Ca2+ channel-dependent and -independent actions of pinacidil. Circulation research, 1995, Volume: 77, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Analysis of Variance; Angiotensin II; Animals; Arterioles; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Diltiazem; Guanidines; In Vitro Techniques; Kidney; Microcirculation; Pinacidil; Potassium Channels; Rats; Renal Circulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	1995
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle. The International journal of biochemistry, 1993, Volume: 25, Issue:4 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Potassium Chloride; Sarcoplasmic Reticulum; Swine; Verapamil	1993
Specific bindings of [3H](+)PN200-110 and [125I]omega-conotoxin to crude membranes from differentiated NG108-15 cells. Neurochemical research, 1993, Volume: 18, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Bucladesine; Cell Differentiation; Cell Membrane; Diltiazem; Glioma; Hybrid Cells; Isradipine; Mollusk Venoms; Neuroblastoma; Nitrendipine; omega-Conotoxin GVIA; Potassium Chloride; Rats; Tumor Cells, Cultured; Verapamil	1993
Effect of nimodipine, diltiazem and BAY K 8644 on the behavioural and neurochemical changes associated with naloxone-precipitated withdrawal in the rat. A comparison with clonidine. General pharmacology, 1993, Volume: 24, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Brain Chemistry; Clonidine; Diltiazem; Hydroxyindoleacetic Acid; Male; Morphine Dependence; Naloxone; Nimodipine; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Substance Withdrawal Syndrome	1993
Antidystonic effects of L-type Ca2+ channel antagonists in a hamster model of idiopathic dystonia. European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cricetinae; Diltiazem; Dystonia; Female; Male; Nimodipine	1996
Effect of the Ca(2+)-channel agonist Bay K 8644 on the contractile responses in human placental veins. Journal of autonomic pharmacology, 1996, Volume: 16, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Placenta; Potassium; Pregnancy; Regional Blood Flow; Serotonin; Veins	1996
Effects of N- and L-type calcium channel antagonists on the responses of nociceptive spinal cord neurons to mechanical stimulation of the normal and the inflamed knee joint. Journal of neurophysiology, 1996, Volume: 76, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Diltiazem; Drug Evaluation, Preclinical; Inflammation; Knee Joint; Male; Neurons; Nimodipine; Nociceptors; omega-Conotoxin GVIA; Peptides; Rats; Rats, Wistar; Reference Values; Spinal Cord; Stress, Mechanical	1996
Involvement of calcium in the cardiac depressant actions of a garlic dialysate. Journal of ethnopharmacology, 1997, Volume: 55, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Dialysis; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Garlic; Heart Atria; Male; Myocardial Contraction; Nifedipine; Plant Extracts; Plants, Medicinal; Rats; Verapamil	1997
Potassium current oscillations across the rabbit lens epithelium. Experimental eye research, 1997, Volume: 65, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Chelating Agents; Diltiazem; Egtazic Acid; Electrophysiology; Epithelium, Corneal; In Vitro Techniques; Models, Biological; Nifedipine; Potassium Channels; Rabbits; Sodium-Potassium-Exchanging ATPase	1997
The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells. Journal of neurochemistry, 1997, Volume: 69, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholinesterase; Amyloid beta-Peptides; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Carcinoma, Embryonal; Diltiazem; Gene Expression Regulation, Enzymologic; Kinetics; Marine Toxins; Nifedipine; Oxocins; Peptide Fragments; Tumor Cells, Cultured; Verapamil	1997
Frequency dependence in the action of the class III antiarrhythmic drug dofetilide is modulated by altering L-type calcium current and digitalis glucoside. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Ion Transport; Male; Membrane Potentials; Ouabain; Phenethylamines; Sulfonamides	1998
Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arylamine N-Acetyltransferase; Atropine; Bungarotoxins; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cells, Cultured; Diltiazem; Exocytosis; Glutamic Acid; Melatonin; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; Nitrendipine; Oxotremorine; Parasympathetic Nervous System; Pineal Gland; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Synaptic Vesicles; Tubocurarine	1998
Sex differences in extracellular and intracellular calcium-mediated vascular reactivity to vasopressin in rat aorta. European journal of pharmacology, 1998, Nov-20, Volume: 361, Issue:2-3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Potassium Chloride; Rats; Rats, Sprague-Dawley; Sex Characteristics; Simvastatin; Vasoconstriction; Vasopressins	1998
L-type calcium channels contribute to the tottering mouse dystonic episodes. Molecular pharmacology, 1999, Volume: 55, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Channels, L-Type; Diltiazem; Dystonia; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mutation; Nitrendipine; RNA, Messenger; Seizures	1999
Calcium channel activation and self-biting in mice. Proceedings of the National Academy of Sciences of the United States of America, 1999, Dec-21, Volume: 96, Issue:26 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior	1999
Dihydropyridine-sensitive Ca(2+) channels in human glomerular mesangial cells. American journal of physiology. Renal physiology, 2000, Volume: 278, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Calcium; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Fura-2; Glomerular Mesangium; Humans; Patch-Clamp Techniques; Potassium	2000
Amlodipine increases nitric oxide synthesis in cytokine-stimulated cultured vascualar smooth muscle cells. Journal of hypertension, 2000, Volume: 18, Issue:11 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Gene Expression Regulation, Enzymologic; Interleukin-1; Muscle, Smooth, Vascular; NF-kappa B; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Sprague-Dawley; RNA, Messenger	2000
Distinct roles for L- and T-type Ca(2+) channels in regulation of atrial ANP release. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atrial Natriuretic Factor; Bodily Secretions; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Diltiazem; Extracellular Space; Heart Atria; In Vitro Techniques; Mibefradil; Myocardial Contraction; Myocardium; Rabbits; Stroke Volume	2000
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture. American journal of physiology. Cell physiology, 2001, Volume: 280, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil	2001
Channels involved in transient currents unmasked by removal of extracellular calcium in cardiac cells. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cesium; Chelating Agents; Diltiazem; Drug Resistance; Egtazic Acid; Electric Conductivity; Heart Ventricles; Isoproterenol; Kinetics; Magnesium; Membrane Potentials; Myocardium; Nifedipine; Patch-Clamp Techniques; Potassium; Receptors, Adrenergic, beta; Swine; Verapamil	2002
Increased cAMP as a positive inotropic factor for mammalian skeletal muscle in vitro. Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:10 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Bucladesine; Caffeine; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cyclic AMP; Dantrolene; Diltiazem; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Mice; Muscle Relaxants, Central; Muscle, Skeletal; Sarcolemma; Sarcoplasmic Reticulum; Time Factors	2003
Ultrastructural comparison of developing mouse embryonic stem cell- and in vivo-derived cardiomyocytes. Cell biology international, 2006, Volume: 30, Issue:10 Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Biomarkers; Calcium Channel Agonists; Calcium Channel Blockers; Carbachol; Cardiotonic Agents; Cell Differentiation; Cells, Cultured; Diltiazem; Embryonic Stem Cells; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Phenylephrine; Phosphodiesterase Inhibitors; Propranolol; Time Factors	2006
Competitive and cooperative effects of Bay K8644 on the L-type calcium channel current inhibition by calcium channel antagonists. The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Algorithms; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Felodipine; Ion Channel Gating; Male; Membrane Potentials; Models, Biological; Myocytes, Cardiac; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Wistar; Verapamil	2007
Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways. European journal of pharmacology, 2008, Feb-12, Volume: 580, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Benzopyrans; Caesalpinia; Caffeine; Calcium; Diltiazem; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Indenes; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide Synthase; Phenylephrine; Pinacidil; Potassium Chloride; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction	2008
Acetylcholine induces Ca2+ signaling in chicken retinal pigmented epithelial cells during dedifferentiation. American journal of physiology. Cell physiology, 2009, Volume: 296, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Signaling; Cell Dedifferentiation; Cell Differentiation; Cells, Cultured; Chick Embryo; Chickens; Cholinergic Agents; Diltiazem; Nicotine; Nicotinic Agonists; Receptors, Muscarinic; Receptors, Nicotinic; Retinal Pigment Epithelium	2009
D-cis-Diltiazem Can Produce Oxidative Stress in Healthy Depolarized Rods In Vivo. Investigative ophthalmology & visual science, 2018, 06-01, Volume: 59, Issue:7 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dark Adaptation; Diltiazem; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Retinal Degeneration; Retinal Rod Photoreceptor Cells; Superoxides; Tomography, Optical Coherence	2018
Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca Cell, 2019, 05-30, Volume: 177, Issue:6 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cryoelectron Microscopy; Diltiazem; Ligands; Male; Models, Molecular; Nifedipine; Rabbits; Verapamil	2019