bay-k-8644 has been researched along with dihydropyridines in 272 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 80 (29.41) | 18.7374 |
| 1990's | 157 (57.72) | 18.2507 |
| 2000's | 30 (11.03) | 29.6817 |
| 2010's | 2 (0.74) | 24.3611 |
| 2020's | 3 (1.10) | 2.80 |
| Authors | Studies |
|---|---|
| Cherksey, B; Llinás, R; Sugimori, M; Usowicz, MM | 1 |
| Gaviraghi, G; Giacometti, A; Micheli, D; Quartaroli, M; Trist, D | 1 |
| Lory, P; Schwartz, A; Varadi, G | 1 |
| Hallaq, H; Leaf, A; Smith, TW | 1 |
| Bodi, I; Itagaki, K; Klöckner, U; Koch, WJ; Schwartz, A; Slish, DF | 1 |
| Goldmann, S; Stoltefuss, J; Triggle, DJ; Zheng, W | 1 |
| García, AG; López, MG; Shukla, R; Wakade, AR | 1 |
| Baumgarten, LB; Toscas, K; Villereal, ML | 1 |
| Ambroz, C; Catt, KJ | 1 |
| Alonso, S; Artalejo, CR; Cillero, J; Fau de Casa-Juana, M; García, AG; González-Morales, MA; López, MG; Santos, L; Sunkel, CE; Villarroya, M | 1 |
| Bergamaschi, S; Govoni, S; Grimaldi, M; Meucci, O; Schettini, G; Scorziello, A; Yasumoto, T | 1 |
| Taglietti, V; Toselli, M | 1 |
| Catt, KJ; Iida, T; Krsmanovic, LZ; Mellon, PL; Merelli, F; Stojilković, SS; Zheng, L | 1 |
| Babcock, DF; Corron, ME; Florman, HM; Kim, TD | 1 |
| Liu, J; Slomiany, A; Slomiany, BL | 1 |
| Dolphin, AC; Sweeney, MI | 1 |
| Brisac, AM; Dubray, C; Huguet, F; Roche, A | 1 |
| Giesen-Crouse, E; Morain, P; Peglion, JL | 1 |
| Dierssen, M; Flórez, J; Hurlé, MA | 1 |
| Bourson, A; Moser, PC | 1 |
| Herbette, LG; Mason, RP; Moring, J | 1 |
| Randic, M; Ryu, PD | 1 |
| Battaini, F; Bergamaschi, S; Govoni, S; Meucci, O; Parenti, M; Schettini, G; Trabucchi, M | 1 |
| Cuccaro, ML; Jacobs, LS; Lorenson, MY | 1 |
| Gainullin, R; Saxon, M | 1 |
| Bolger, GT; O'Neill, SK | 2 |
| Carbone, E; Clementi, F; Sher, E | 1 |
| Bolger, GT; Campbell, N; Crowley, M; McKay, DW; O'Neill, SK; Triggle, CR | 1 |
| Anderson, AJ; Clarke, B; Duncan, GP; Greenhouse, R; Patmore, L; Pfister, JR | 1 |
| Boonen, HC; De Mey, JG | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Jacobs, LS; Jones, SW | 1 |
| Brennan, CH; Littleton, JM | 1 |
| Gray, DB; Manthay, N; Pilar, G; Zelazny, D | 1 |
| Hayden, HC; Herbette, LG; Mason, RP; Moring, J; Salomon, RM; Shoemaker, WJ; Skita, V | 1 |
| Bacskai, BJ; Friedman, PA | 1 |
| Naitoh, T; Sugimoto, T; Toyo-Oka, T | 1 |
| Bartrup, JT; Stone, TW | 2 |
| Kocsis, JD; O'Regan, MH; Waxman, SG | 1 |
| Kunze, DL; Ritchie, AK | 1 |
| Gandhi, VC; Jones, DJ | 1 |
| Bieger, D; Triggle, CR | 1 |
| Bolger, GT; O'Neill, SK; Triggle, CR | 1 |
| Peers, C | 1 |
| Fox, AP; Hirning, LD; Miller, RJ | 1 |
| Florio, T; Grimaldi, M; Landolfi, E; Meucci, O; Schettini, G; Scorziello, A; Ventra, C | 1 |
| Hisa, H; Satoh, S; Suzuki-Kusaba, M; Takahara, A | 1 |
| Astier, H; Roussel, JP | 1 |
| Abraham, C; Aptel, H; Lombet, A; Nagel, N; Peglion, JL; Randle, JC; Renaud, JF | 1 |
| Hurnák, O; Krizanová, O; Proks, P; Zachar, J | 1 |
| Dubyak, GR; Jones, SW; Marks, TN | 1 |
| Fox, AP; Scroggs, RS | 1 |
| Clark, RB; Giles, WR; Gotoh, Y; Imaizumi, Y; Shibata, EF; Watanabe, M | 1 |
| Chaptal, PA; Nargeot, J; Ouadid, H; Richard, S; Séguin, J | 1 |
| Singer, JJ; Vivaudou, MB; Walsh, JV | 1 |
| Goldstein, M; Masuyama, Y; Tsuda, K; Tsuda, S | 1 |
| Halushka, PV; Mais, DE; Mayeux, PR | 1 |
| Regan, LJ | 1 |
| Lory, P; Schultz, D; Schwartz, A; Varadi, G; Varadi, M | 1 |
| Dannies, PS; Law, GJ; Pachter, JA | 1 |
| Barnett, JV; Galper, JB; Hehn, GM; Quay, SC; Tan, W | 1 |
| Brocklehurst, KW; Ceña, V; Pollard, HB; Rojas, E | 1 |
| Chaĭka, AD; Kolchinskaia, LI; Kravets, LA; Sokolov, IuV | 1 |
| Brawley, RM; Gutierrez, LM; Hosey, MM | 1 |
| de Pascual, R; Gandía, L; García, AG; López, MG; Michelena, P | 1 |
| Suszkiw, JB; Tomsig, JL | 1 |
| Rampe, D; Triggle, DJ; Zheng, W | 1 |
| Hescheler, J; Scherübl, H | 1 |
| Lin, F; Moran, O; Sciancalepore, M; Zegarra-Moran, O | 1 |
| Nelson, MT; Quayle, JM; Standen, NB; Worley, JF | 1 |
| Alfaro, MJ; Colado, MI; Del Val, V; López, F; Martín, MI | 1 |
| Baldy-Moulinier, M; Diochot, S; Nargeot, J; Richard, S; Valmier, J | 1 |
| Chang, KJ; Collins, MA; Xu, SF | 1 |
| Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A | 1 |
| Hawthorn, M; Triggle, DJ; Zheng, W | 1 |
| de Ree, MM; Gähwiler, BH; Knot, HJ; Rüegg, UT | 1 |
| Drímal, J | 2 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 1 |
| Schramm, M; Towart, R | 1 |
| Rubanyi, GM; Schwartz, A; Vanhoutte, PM | 1 |
| Creba, JA; Karobath, M | 1 |
| Glossmann, H; Goll, A; Moosburger, K; Striessnig, J | 1 |
| Callewaert, G; Droogmans, G | 1 |
| Kongsamut, S; Miller, RJ | 1 |
| Bean, BP; Hermsmeyer, K; Puga, A; Sturek, M | 1 |
| Ehrhard, P; Fischli, W; Holck, M; Kozlowski, R; Osterrieder, W | 1 |
| Bean, BP; Hess, P; Lansman, JB; Nilius, B; Nowycky, MC; Tsien, RW | 1 |
| Miller, RJ; Murphy, SN; Thayer, SA | 1 |
| Hoffmeister, F; Tettenborn, D | 1 |
| Chernow, B; Ives, N; King, JW; Roth, BL | 1 |
| Beyer, T; Gansohr, N; Gjörstrup, P; Ravens, U | 1 |
| Gurney, AM; Nerbonne, JM | 1 |
| Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A | 1 |
| Brennan, CH; Charles, S; Hudspith, MJ; Littleton, JM | 1 |
| Challoner-Hue, L; Steele, TH | 1 |
| Hosey, MM; Maan, AC | 1 |
| Atchison, WD; O'Leary, SM | 1 |
| Skattebøl, A; Triggle, DJ | 1 |
| Harper, JC; Littleton, JM; Pagonis, C | 1 |
| Brisac, AM; Champeroux, P; Gerard, P; Huguet, F; Laurent, S; Lucet, B; Montastruc, JL; Narcisse, G; Schmitt, H | 1 |
| Dunlap, K; Holz, GG; Kream, RM | 1 |
| Basile, AS; Bolger, GT; Lesieur, P; Skolnick, P | 1 |
| Furukawa, T; Katsuragi, T; Usune, S | 1 |
| Hashimoto, K; Motomura, S | 1 |
| Oswald, RE; Simasko, SM; Weiland, GA | 1 |
| Lamb, GD; Walsh, T | 1 |
| Noronha-Blob, L; Richard, C; U'Prichard, DC | 1 |
| Bacciottini, L; Carlà, V; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Knepel, W; Meier, K; Schöfl, C | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Hamilton, SL; Imoto, Y; Yatani, A | 1 |
| Warbanow, W; Will-Shahab, L | 1 |
| Massieu, L; Tapia, R | 1 |
| Dunn, SM | 2 |
| Brisac, AM; Lacolley, P; Laurent, S; Legrand, M; Schmitt, H; Tsoucaris-Kupfer, D | 2 |
| Cook, ME; Leslie, SW; Woodward, JJ | 1 |
| Bergamaschi, S; Cominetti, P; Govoni, S; Parenti, M; Trabucchi, M | 1 |
| Bihoreau, C; Clauser, H; Drouva, SV; Kordon, C; Laplante, E; Rasolonjanahary, R; Rerat, E | 1 |
| Catt, KJ; Hausdorff, WP | 1 |
| Burnstock, G; MacKenzie, I; Manzini, S | 1 |
| Borges, R; Cárdenas, AM; Esteban, C; García, AG; Montiel, C | 1 |
| Bogónez, E; Martínez-Serrano, A; Satrústegui, J; Vitórica, J | 1 |
| Dunér-Engström, M; Fredholm, BB | 1 |
| Guggino, SE; Lajeunesse, D; Snyder, SH; Wagner, JA | 1 |
| Lacerda, AE; Poder, TC; Silberberg, SD | 1 |
| Brown, AM; Skattebøl, A; Triggle, DJ | 1 |
| Boarder, MR; Marriott, DB; Owen, PJ | 1 |
| Anderson, EG; Scroggs, RS | 1 |
| Childs, M; Laurent, S; Martin, P; Massol, J; Puech, AJ | 1 |
| Chiu, M; Dionne, MA; Marsh, JD; Smith, TW | 1 |
| Panzer-Knodle, S; Papaioannou, S; Yang, PC | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Mattera, R; Yatani, A | 1 |
| Haleen, SJ; Major, TC; Pugsley, TA; Sircar, I; Steffen, RP; Taylor, MD; Weishaar, RE | 1 |
| Kim, YI; Pancrazio, JJ; Viglione, MP | 1 |
| Olsen, R; Powis, G; Seewald, M | 1 |
| Fujisue, T; Ichida, S; Masada, A; Matsuda, N; Yoshioka, T | 1 |
| Imoto, K; Mikami, A; Mori, Y; Narumiya, S; Niidome, T; Numa, S; Takeshima, H; Tanabe, T | 1 |
| Birnbaumer, L; Brown, AM; Campbell, KP; Horne, W; Kim, HS; Lacerda, AE; Perez-Reyes, E; Rampe, D; Wei, XY | 1 |
| Al-Dahan, MI; Thalmann, RH | 1 |
| Brown, AM; Lacerda, AE | 1 |
| Aaronson, PI; Bolton, TB; Lang, RJ; MacKenzie, I | 1 |
| D'Orleans-Juste, P; De Nucci, G; Vane, JR | 1 |
| Dutton, GR; Philibert, RA | 1 |
| Flockerzi, V | 1 |
| Briand, V; Laurent, S; Schmitt, H | 1 |
| Jones, SW; Marks, TN | 1 |
| Gotoh, Y; Imaizumi, Y; Kawai, T; Kumadani, S; Watanabe, M | 1 |
| Fichtner, H; Herzig, JW; Kohlhardt, M | 1 |
| Bieger, D; Bolger, GT; Hashim, MA | 1 |
| Collins, F; Lile, JD | 1 |
| Caffrey, JM; Farach-Carson, MC | 1 |
| Ashcroft, FM; Rorsman, P; Smith, PA | 1 |
| Bourson, A; Gower, AJ; Mir, AK; Moser, PC | 1 |
| Buisson, N; Gourdji, D; Laverrière, JN; Martial, JA; Richard, JL; Tixier-Vidal, A | 1 |
| Carpentier, RG; Carryl, OR; Isaacson, RL; Salvatici, PP | 1 |
| Freedman, SB; Kongsamut, S; Miller, RJ | 1 |
| Gizinski, MJ; Schumaker, KS | 2 |
| Artalejo, CR; Cillero, FJ; de Casa-Juana, MF; de Pascual, R; García, AG; González-Morales, MA; López, MG; Priego, J; Sunkel, C; Villarroya, M | 1 |
| Fuchs, J; Klaus, W; Ratke, R; Rösen, R; Rump, AF; Sigmund, B | 1 |
| de la Fuente, M; Fonteríz, RI; Gandía, L; García, AG; García-Sancho, J; López, MG; Villarroya, M | 1 |
| de Boland, AR; Vazquez, G | 1 |
| Bagó, A; Deák, F; Hunyady, L; Rohács, T; Spät, A | 1 |
| Brooker, G; Carlson, RO; Masco, D; Spiegel, S | 1 |
| Hettrick, DA; Pagel, PS; Warltier, DC | 1 |
| Friedman, PA; Gesek, FA; Matsunaga, H; Stanton, BA | 1 |
| Ito, S; Kitamura, N; Nakazato, Y; Ohta, T | 1 |
| Browaeys-Poly, E; Guilbault, P; Ouadid, H; Vilain, JP | 1 |
| Lemos, JR; Treistman, SN; Wang, G; Wang, X | 1 |
| Bogdanov, K; Hallaq, H; Lakatta, E; Leaf, A; Pepe, S; Spurgeon, H | 1 |
| Berkels, R; Boller, M; Fricke, U; Klaus, W; Rösen, R; Rump, AF | 1 |
| Albillos, A; Artalejo, AR; Carbone, E; Gandía, L; García, AG; López, MG | 1 |
| Friedman, PA; Gesek, FA | 1 |
| Acerbo, P; Nobile, M | 1 |
| Artalejo, AR; de la Fuente, MT; del Valle, M; Gandía, L; García, AG; Montiel, C; Vinet, R | 1 |
| Croxton, TL; Farley, LS; Hirshman, CA; Vannier, C | 1 |
| Berger, AJ; Umemiya, M | 1 |
| Guérineau, NC; Israel, JM; Lledo, PM; Verrier, D | 1 |
| Miras-Portugal, MT; Rodriguez-Pascual, F; Torres, M | 1 |
| Beam, KG; Dirksen, RT | 1 |
| Badia, A; Clos, MV; Garcia, A; Pastor, C; Sabrià, J | 1 |
| Cox, TC; Tiwari-Woodruff, SK | 1 |
| Duprat, AM; Leclerc, C; Moreau, M | 1 |
| Berrow, N; Brickley, K; Campbell, V; Dolphin, AC; Page, K; Wade, R | 1 |
| Gu, R; Jiang, S; Su, Z | 1 |
| Albillos, A; Borges, R; Gandía, L; García, AG | 1 |
| Fukata, F; Kanda, M; Kurahashi, K; Matsui, H; Nakamura, S; Shirahase, H; Wada, K | 1 |
| Fraser, S; Kenny, BA; Spedding, M | 1 |
| Kimura, T; Satoh, S; Takeuchi, A | 1 |
| Horowitz, B; Hume, JR; Kenyon, JL; Overturf, K; Rich, A; Sanders, KM | 1 |
| García, AG; Jiménez, RR; López, MG; Maroto, R; Sancho, C | 1 |
| Bolton, TB; Hering, S; Hughes, AD; Timin, EN | 1 |
| Foster, RW; Green, KA; Small, RC | 1 |
| Momiyama, A; Yawo, H | 1 |
| Arimura, T; Kobayashi, K; Okada, T; Piccolino, M; Tachibana, M | 1 |
| Takeda, Y | 1 |
| Barnett, JV; Galper, JB; Greiser, C; Hehn, G; Marsh, JD; Pietrobon, D; Tan, W | 1 |
| Biancardi, E; Carbone, E; Lovallo, M; Pollo, A; Sher, E; Socci, C | 1 |
| Nargeot, J; Neveu, D; Richard, S | 1 |
| Fricke, U; Klaus, W; Ratke, R; Rump, AF | 1 |
| Ichihara, K; Kamei, H; Kanda, A; Miyake, H; Miyoshi, K; Nagasaka, M | 1 |
| Audy, MC; Bonnin, M; Bouali-Benazzouz, R | 1 |
| MacVicar, BA; Pittman, QJ; Williams, PJ | 1 |
| Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ | 1 |
| Ayata, C; Dalkara, T; Demirci, M; Erdemli, G; Onur, R | 1 |
| Garcia, MC; Sanchez, JA; Sharma, VK; Sheu, SS | 1 |
| Kobayashi, D; Miyamoto, K; Ohmae, S; Sanae, F; Takag, K | 1 |
| Bindokas, VP; Ishida, AT | 1 |
| Balla, T; Catt, KJ; Rössig, L; Zólyomi, A | 1 |
| Kamishima, T; McCarron, JG | 1 |
| Brown, DA; Filippov, AK | 1 |
| Boutjdir, M; Chen, L; el-Sherif, N | 1 |
| Ananthanarayanan, VS; Zhorov, BS | 1 |
| Bastié, MJ; Bertrand, V; Bouisson, M; Pradayrol, L; Vaysse, N | 1 |
| Biancardi, E; Carbone, E; Clementi, F; Davalli, AM; Pollo, A; Pontiroli, AE; Pozza, G; Sher, E; Socci, C | 1 |
| Guerrier, P; Leclerc, C; Moreau, M | 1 |
| Ferroni, A; Galli, A; Mazzanti, M | 1 |
| Brousal, JP; Catterall, WA; Gallombardo, PA; Hockerman, GH; Johnson, BD; Lai, Y; Peterson, BZ; Scheuer, T | 1 |
| Brochu, M; Jodoin, S; Picard, S; St-Louis, J | 1 |
| Erxleben, C; Rathmayer, W | 1 |
| Borowicz, KK; Czuczwar, SJ; Gasior, M; Kleinrok, Z | 1 |
| Gan, J; Iuvone, PM | 1 |
| Hofmann, F; Ito, H; Klugbauer, N | 1 |
| Gollasch, M; Haase, H; Haller, H; Lindschau, C; Luft, FC; Morano, I; Ried, C | 1 |
| Diéguez, G; Fernández, N; García, AG; García, JL; López, MG | 1 |
| Ouadid-Ahidouch, H | 1 |
| Kanaya, N; Kawana, S; Kimura, H; Matsumoto, M; Miyamoto, A; Namiki, A; Ohshika, H; Tsuchida, H | 1 |
| Bennett, HP; James, S; Lembessis, P; Macleod, RJ | 1 |
| de la Villa, P; Kaneko, A; Vaquero, CF | 1 |
| Vargas, FF; Vinet, R | 1 |
| Guppy, LJ; Littleton, JM | 1 |
| Athmann, C; Kang, T; Sachs, G; Walsh, JH; Zeng, N | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Bito, H; Deisseroth, K; Mermelstein, PG; Tsien, RW | 1 |
| Thoreson, WB | 1 |
| Hanna, ST; Tang, G; Wang, R; Wu, L; Wu, Y | 1 |
| Hohenegger, M; Kress, HG; Weigl, LG | 1 |
| Hayashi, M; Nakazato, Y; Saruta, T; Yamaji, Y | 1 |
| Kang, TM; Kim, CH; Kim, KW; Kim, YI; Park, MK; Rhee, JC; Rhee, PL; So, I; Uhm, DY | 1 |
| Chang, AS; Chang, SM; Choobineh, E; Collins, PL; Lundgren, DW; Moore, JJ | 1 |
| Bell, DC; Berrow, NS; Brust, PF; Butcher, AJ; Dolphin, AC; Nesterova, A; Nürnberg, B; Page, KM; Seabrook, GR; Stauderman, KA | 1 |
| Kan, E; Kelly, JE; Lokuta, AJ; Nishio, M; Sagawa, K; Sagawa, T; Tsai, J; Wasserstrom, JA | 1 |
| Gerzanich, V; Simard, JM; West, GA; Zhang, F | 1 |
| Carroll, EM; Collins, PL; Gianopoulos, JG | 1 |
| Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L | 1 |
| Chang, W; Chen, TH; Mikala, G; Pratt, SA; Schwartz, A; Shoback, D; Tu, CL | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Lipscombe, D; Xu, W | 1 |
| Brown, G; Losonczy, G; Schoenl, M; Venuto, R | 1 |
| Borowicz, KK; Czuczwar, SJ; Kleinrok, Z | 1 |
| Kim, YC; Koh, SD; Sanders, KM | 1 |
| Akaike, N; Ishibashi, H; Lawlor, GF; Rhee, JS; Wang, ZM; Watanabe, Y | 1 |
| Birkenbeil, H; Dedos, SG | 1 |
| Armstrong, DL; Birnbaumer, L; Darden, T; Erxleben, C; Gomez-Alegria, C; Mori, Y | 1 |
| Ricci, AJ; Schnee, ME | 1 |
| Hino, N; Masumiya, H; Ochi, R; Tsujikawa, H | 1 |
| Grabner, M; Heinzle, T; Hoda, JC; Koschak, A; Reimer, D; Striessnig, J; Walter, D | 1 |
| Cota, G; Espinosa, JL; López-Domínguez, AM; López-Santiago, LF; Navarrete, A; Vega, AV | 1 |
| Berjukov, S; Bova, S; Cavalli, M; Hering, S; Hetzenauer, A; Huber, IG; Koschak, A; Pongs, O; Renström, E; Rorsman, P; Singewald, N; Sinnegger-Brauns, MJ; Striessnig, J; Waldschütz, R; Walter, D; Wietzorrek, G | 1 |
| Darcy, DP; Isaacson, JS; Murphy, GJ | 1 |
| Aishima, M; Ito, Y; Teramoto, N; Tomoda, T; Zhu, HL | 1 |
| Dupere, JR; Payne, CE; Tringham, EW; Usowicz, MM | 1 |
| Davood, A; Iman, M; Nematollahi, AR; Shafiee, A | 1 |
| Cao, YX; Zhang, LX; Zhang, SQ | 1 |
| Rustenbeck, I; Seemann, N; Welling, A | 1 |
| Gao, S; Yan, N | 1 |
| Bansal, N; Khurana, K; Kumar, M | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
3 review(s) available for bay-k-8644 and dihydropyridines
| Article | Year |
|---|---|
Modulation of calcium channel function by drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Electric Conductivity; Heart Rate; Homeostasis; Humans; Ion Channels; Membrane Potentials; Nifedipine; Pyridines; Receptors, Cell Surface; Structure-Activity Relationship | 1985 |
Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Dihydropyridines; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Models, Biological; Nifedipine; Phosphorylation; Pyridines; Receptors, Adrenergic, beta | 1986 |
Direct G-protein regulation of Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Thionucleotides | 1989 |
269 other study(ies) available for bay-k-8644 and dihydropyridines
| Article | Year |
|---|---|
P-type calcium channels in the somata and dendrites of adult cerebellar Purkinje cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dendrites; Dihydropyridines; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Purkinje Cells | 1992 |
Analysis of the interaction between lacidipine and BAY K 8644 in two isolated rabbit arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Models, Biological; Rabbits; Vasoconstriction | 1992 |
The beta subunit controls the gating and dihydropyridine sensitivity of the skeletal muscle Ca2+ channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Biophysical Phenomena; Biophysics; Calcium Channels; Cell Line; Dihydropyridines; Electrochemistry; Ion Channel Gating; Mice; Muscles; Protein Conformation | 1992 |
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Fatty Acids, Unsaturated; Fish Oils; Heart; In Vitro Techniques; Ion Channel Gating; Myocardial Contraction; Nitrendipine; Ouabain; Rats; Verapamil | 1992 |
Native-type DHP-sensitive calcium channel currents are produced by cloned rat aortic smooth muscle and cardiac alpha 1 subunits expressed in Xenopus laevis oocytes and are regulated by alpha 2- and beta-subunits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium Channels; Cloning, Molecular; Dihydropyridines; Electric Conductivity; Female; Gene Expression Regulation; Muscle, Smooth, Vascular; Myocardium; Oocytes; Rabbits; Rats; Xenopus laevis | 1992 |
Pharmacologic and radioligand binding studies of 1,4-dihydropyridines in rat cardiac and vascular preparations: stereoselectivity and voltage dependence of antagonist and activator interactions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; Drug Antagonism; Heart; In Vitro Techniques; Isradipine; Male; Muscle Contraction; Nifedipine; Radioligand Assay; Rats | 1992 |
A dihydropyridine-resistant component in the rat adrenal secretory response to splanchnic nerve stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Dihydropyridines; Drug Resistance; Electric Stimulation; Hexamethonium; Hexamethonium Compounds; Isradipine; Male; Neural Conduction; Nicotine; Potassium; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Splanchnic Nerves | 1992 |
Dihydropyridine-sensitive L-type Ca2+ channels in human foreskin fibroblast cells. Characterization of activation with the growth factor Lys-bradykinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cells, Cultured; Dihydropyridines; Fibroblasts; Fura-2; Humans; Ion Channel Gating; Kallidin; Nitrendipine | 1992 |
Angiotensin II receptor-mediated calcium influx in bovine adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Calcium Channels; Cattle; Cells, Cultured; Dihydropyridines; GTP-Binding Proteins; Imidazoles; Lanthanum; Losartan; Pertussis Toxin; Receptors, Angiotensin; Tetrazoles; Virulence Factors, Bordetella; Zona Glomerulosa | 1992 |
Synthesis of 3-[(2,3-dihydro-1,1,3-trioxo-1,2-benzisothiazol-2-yl)alkyl] 1,4-dihydropyridine-3,5-dicarboxylate derivatives as calcium channel modulators.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cations; Dihydropyridines; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Rabbits; Rats; Rats, Inbred Strains; Thiazoles | 1992 |
Maitotoxin-induced intracellular calcium rise in PC12 cells: involvement of dihydropyridine-sensitive and omega-conotoxin-sensitive calcium channels and phosphoinositide breakdown.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cytosol; Dihydropyridines; Dose-Response Relationship, Drug; GTP-Binding Proteins; Marine Toxins; Nicardipine; omega-Conotoxins; Oxocins; PC12 Cells; Peptides, Cyclic; Pertussis Toxin; Phosphatidylinositols; Rats; Sodium; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Kinetic and pharmacological properties of high- and low-threshold calcium channels in primary cultures of rat hippocampal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Electrophysiology; Hippocampus; Kinetics; Neurons; Nickel; omega-Conotoxin GVIA; Peptides, Cyclic; Rats | 1992 |
Gonadotropin-releasing hormone-induced calcium signaling in clonal pituitary gonadotrophs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Dihydropyridines; Endoplasmic Reticulum; Gonadotropin-Releasing Hormone; Ionomycin; Nifedipine; Pituitary Gland; Potassium; Signal Transduction; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin | 1992 |
Activation of voltage-dependent calcium channels of mammalian sperm is required for zona pellucida-induced acrosomal exocytosis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acrosome; Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cattle; Dihydropyridines; Exocytosis; Isradipine; Male; Mice; Nitrendipine; Sheep; Spermatozoa; Zona Pellucida | 1992 |
Platelet-derived growth factor activation of gastric mucosal calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; Gastric Mucosa; Isradipine; Kinetics; Liposomes; Phosphorylation; Platelet-Derived Growth Factor; Rats; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor | 1992 |
1,4-Dihydropyridines modulate GTP hydrolysis by Go in neuronal membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Calcium Channels; Cell Membrane; Cerebral Cortex; Dihydropyridines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immune Sera; Male; Neurons; Rats; Rats, Inbred Strains | 1992 |
Absence of a direct coupling of a G protein to dihydropyridine binding sites in rat heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Heart; Male; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Wistar | 1992 |
Ca2+ channel inhibition in a rat osteoblast-like cell line, UMR 106, by a new dihydropyridine derivative, S11568.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channel Blockers; Cell Line; Dihydropyridines; Electrophysiology; Osteoblasts; Rats | 1992 |
Opiate analgesia and calcium channels modulation by dihydropyridines under acute and tolerant conditions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesia; Animals; Calcium Channels; Dihydropyridines; Drug Tolerance; Fentanyl; Male; Nimodipine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sufentanil | 1990 |
Yawning induced by apomorphine, physostigmine or pilocarpine is potentiated by dihydropyridine calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Apomorphine; Atropine; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Male; Physostigmine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Dopamine; Sulpiride; Yawning | 1990 |
A molecular model involving the membrane bilayer in the binding of lipid soluble drugs to their receptors in heart and brain.
Topics: 1,2-Dipalmitoylphosphatidylcholine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Brain; Cholesterol; Dihydropyridines; Gels; Lipid Bilayers; Membranes; Models, Chemical; Models, Molecular; Myocardium; Nifedipine; Rats; Receptors, Drug; Sarcolemma; Solubility | 1990 |
Low- and high-voltage-activated calcium currents in rat spinal dorsal horn neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium Channel Blockers; Calcium Channels; Cobalt; Dihydropyridines; Electrophysiology; In Vitro Techniques; Neural Conduction; Neurons; Nickel; Rats; Spinal Cord; Substance P | 1990 |
Modulation of dihydropyridine-sensitive calcium channels: a role for G proteins.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; GTP-Binding Proteins; Guanosine Triphosphate; Isradipine; Neurons; Nitrendipine; Oxadiazoles; Rats; Tumor Cells, Cultured | 1990 |
Calcium release from pituitary secretory granules: modulation by thiols, disulfides, and dihydropyridine calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cattle; Cysteine; Cystine; Cytoplasmic Granules; Dihydropyridines; Disulfides; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Mercaptoethanol; Nifedipine; Nimodipine; Pituitary Gland; Potassium Chloride; Sulfhydryl Compounds | 1990 |
Two subtypes of dihydropyridine-sensitive calcium channels in rat ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Female; Heart; In Vitro Techniques; Magnesium; Male; Myocardial Contraction; Myocardium; Nifedipine; Potassium Chloride; Pyridines; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum | 1990 |
The effects of strychnine on the regulation of voltage-dependent calcium channels by dihydropyridines in brain and heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channels; Dihydropyridines; Drug Interactions; Heart; Male; Mice; Myocardial Contraction; Myocardium; Nifedipine; Phencyclidine; Potassium; Rats; Rats, Inbred Strains; Sodium; Strychnine | 1990 |
Ca currents in human neuroblastoma IMR32 cells: kinetics, permeability and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Cell Membrane Permeability; Dihydropyridines; Electric Conductivity; Humans; Kinetics; Mollusk Venoms; Neuroblastoma; Neurons; Nickel; omega-Conotoxin GVIA; Tumor Cells, Cultured | 1990 |
Comparative behavioral, neurochemical and pharmacological activities of dihydropyridine calcium channel activating drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium Channel Agonists; Catecholamines; Chromatography, High Pressure Liquid; Dihydropyridines; Guinea Pigs; Injections, Intraperitoneal; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1990 |
RS 30026: a potent and effective calcium channel agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Cells, Cultured; Chick Embryo; Coronary Vessels; Dihydropyridines; Electrophysiology; Female; Guinea Pigs; Muscle, Smooth, Vascular; Muscles; Myocardial Contraction; Papillary Muscles; Structure-Activity Relationship; Swine | 1990 |
Increased calcium sensitivity in isolated resistance arteries from spontaneously hypertensive rats: effects of dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Blockers; Dihydropyridines; Electrochemistry; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nimodipine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance | 1990 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
Dihydropyridine actions on calcium currents of frog sympathetic neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Nifedipine; Rana catesbeiana; Rana pipiens; Sympathetic Nervous System | 1990 |
Second messengers involved in genetic regulation of the number of calcium channels in bovine adrenal chromaffin cells in culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium Channels; Cattle; Cells, Cultured; Chromaffin System; Dihydropyridines; Gene Expression; Inositol Phosphates; Kinetics; Pertussis Toxin; Phorbol Esters; Second Messenger Systems; Up-Regulation; Virulence Factors, Bordetella | 1990 |
Endogenous modulation of ACh release by somatostatin and the differential roles of Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Calcium Channels; Chickens; Choroid; Dihydropyridines; Ganglia, Parasympathetic; Immunologic Techniques; Microscopy, Electron; Potassium; Somatostatin; Synapses | 1990 |
Rat cerebral cortical synaptoneurosomal membranes. Structure and interactions with imidazobenzodiazepine and 1,4-dihydropyridine calcium channel drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Calcium Channel Blockers; Cell Membrane; Cerebral Cortex; Dihydropyridines; Flumazenil; Microscopy, Electron; Models, Molecular; Myelin Basic Protein; Neurons; Nimodipine; Protein Conformation; Rats; Receptors, Cholinergic; Receptors, GABA-A; Ryanodine Receptor Calcium Release Channel; Synaptosomes; X-Ray Diffraction | 1990 |
The effects of dihydropyridine calcium channel modulators on pentylenetetrazole convulsions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Male; Mice; Nifedipine; Nimodipine; Seizures | 1990 |
Activation of latent Ca2+ channels in renal epithelial cells by parathyroid hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Absorption; Animals; Biological Transport; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Dihydropyridines; Epithelium; Exocytosis; Kidney Tubules, Distal; Kinetics; Mice; Microtubules; Nifedipine; Parathyroid Hormone; Peptide Fragments | 1990 |
An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Endothelins; Heart; Isradipine; Kinetics; Liposomes; Microsomes; Oxadiazoles; Proteolipids; Sarcolemma; Swine; Verapamil | 1990 |
Inhibition of adenosine responses of rat hippocampal neurones by nifedipine and BAYK 8644.
Topics: 2-Chloroadenosine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Animals; Dihydropyridines; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Neurons; Nifedipine; Pyramidal Tracts; Rats | 1990 |
Depolarization-dependent actions of dihydropyridines on synaptic transmission in the in vitro rat hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Dihydropyridines; Evoked Potentials; Female; Hippocampus; In Vitro Techniques; Light; Membrane Potentials; Neurons; Nifedipine; Nimodipine; Perfusion; Potassium; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1990 |
Multiple conductance levels of the dihydropyridine-sensitive calcium channel in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cell Line; Dihydropyridines; Electric Conductivity; Humans; Nimodipine; Pituitary Gland, Anterior | 1990 |
Modulation of [3H]serotonin release by dihydropyridines in spinal cord synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Hemodynamics; Male; Mollusk Venoms; Nerve Tissue Proteins; Neurotransmitter Agents; omega-Conotoxin GVIA; Potassium; Rats; Rats, Inbred Strains; Reflex; Serotonin; Spinal Cord; Synaptosomes | 1990 |
Can dihydropyridines enhance photorelaxation of smooth muscle by calcium-independent mechanisms?
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Dihydropyridines; Enzyme Activation; Guanylate Cyclase; In Vitro Techniques; Light; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Photic Stimulation; Rats; Rats, Inbred Strains; SRS-A | 1990 |
Comparative studies with enantiomers of dihydropyridine ligands suggests that there are multiple binding sites associated with the calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain Chemistry; Calcium Channels; Dihydropyridines; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Ligands; Male; Mice; Muscle, Smooth; Myocardium; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Stereoisomerism | 1990 |
Hypoxic suppression of K+ currents in type I carotid body cells: selective effect on the Ca2(+)-activated K+ current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channel Blockers; Carotid Body; Dihydropyridines; Electrophysiology; Hypoxia; Nifedipine; Potassium; Rats | 1990 |
Dihydropyridines alter adenosine sensitivity in the rat hippocampal slice.
Topics: 2-Chloroadenosine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Dipyridamole; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Male; Nifedipine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Vasodilator Agents | 1990 |
Inhibition of calcium currents in cultured myenteric neurons by neuropeptide Y: evidence for direct receptor/channel coupling.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cells, Cultured; Dihydropyridines; Fura-2; Membrane Potentials; Myenteric Plexus; Neurons; Neuropeptide Y; Nitrendipine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1990 |
Dihydropyridine modulation of voltage-activated calcium channels in PC12 cells: effect of pertussis toxin pretreatment.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophysiology; Nicardipine; Pertussis Toxin; Pheochromocytoma; Potassium; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Effects of a novel Ca2+ entry blocker, CD-349, and TMB-8 on renal vasoconstriction induced by angiotensin II and vasopressin in dogs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dogs; Female; Gallic Acid; Heart Rate; Male; Renal Circulation; Vasoconstriction; Vasopressins | 1990 |
Involvement of dihydropyridine-sensitive calcium channels in the GABAA potentiation of TRH-induced TSH release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Drug Synergism; GABA Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Isonicotinic Acids; Male; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Pertussis Toxin; Pituitary Gland; Pyridazines; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone; Virulence Factors, Bordetella | 1990 |
Ca2+ channel inhibition by a new dihydropyridine derivative, S11568, and its enantiomers S12967 and S12968.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Radioisotopes; Cell Line; Dihydropyridines; Electrophysiology; Guinea Pigs; Heart; In Vitro Techniques; Inosine Triphosphate; Isradipine; Male; Muscle, Smooth, Vascular; Myocardium; Oxadiazoles; Rats; Ryanodine; Stereoisomerism | 1990 |
DHP-sensitive Ca2+ channels from crayfish skeletal muscle T-tubules incorporated into planar lipid bilayers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Astacoidea; Calcium Channels; Dihydropyridines; In Vitro Techniques; Lipid Bilayers; Muscles | 1990 |
Calcium currents in the A7r5 smooth muscle-derived cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Biological Transport; Calcium; Calcium Channels; Cell Line; Colforsin; Cytosol; Dihydropyridines; Electric Conductivity; Fluorescence; Isoproterenol; Ligands; Muscle, Smooth, Vascular; Nifedipine; Potassium | 1990 |
Distribution of dihydropyridine and omega-conotoxin-sensitive calcium currents in acutely isolated rat and frog sensory neuron somata: diameter-dependent L channel expression in frog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channels; Dihydropyridines; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Kinetics; Membrane Potentials; Mollusk Venoms; Neurons, Afferent; Nimodipine; omega-Conotoxin GVIA; Peptides, Cyclic; Ranidae; Rats; Species Specificity | 1991 |
Inhibition of transient outward K+ current by DHP Ca2+ antagonists and agonists in rabbit cardiac myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Electrophysiology; Heart; In Vitro Techniques; Myocardium; Nicardipine; Potassium; Rabbits | 1991 |
Properties and Modulation of Ca channels in adult human atrial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Aged; Barium; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Dihydropyridines; Female; Heart Atria; Humans; Male; Middle Aged; Myocardium | 1991 |
Multiple types of Ca2+ channels in visceral smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Bufo marinus; Calcium Channels; Dihydropyridines; Electric Conductivity; Gastric Mucosa; In Vitro Techniques; Kinetics; Muscle, Smooth; Stomach | 1991 |
Effects of Bay K 8644, a Ca2+ channel agonist, on [3H]norepinephrine release in hypothalamus of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Hypertension; Hypothalamus; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System | 1991 |
Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Blood Platelets; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Fura-2; Humans; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Manganese; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyridines; Radioligand Assay; Receptors, Prostaglandin; Receptors, Thromboxane; Stereoisomerism | 1991 |
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats | 1991 |
Acceleration of activation and inactivation by the beta subunit of the skeletal muscle calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Binding Sites; Calcium Channels; Cell Line; Cell Membrane; Dihydropyridines; DNA; Electric Conductivity; Gene Expression; Ion Channel Gating; Isradipine; Kinetics; L Cells; Macromolecular Substances; Muscles; Oxadiazoles; Rabbits; Receptors, Nicotinic; Transfection | 1991 |
Ca2+ channel agonists enhance thyrotropin-releasing hormone-induced inositol phosphates and prolactin secretion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Radioisotopes; Dihydropyridines; Female; In Vitro Techniques; Inositol Phosphates; Nimodipine; Perfusion; Prolactin; Pyridines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Thyrotropin-Releasing Hormone | 1991 |
Effect of manganese (II) bis(glycinate)dichloride on Ca2+ channel function in cultured chick atrial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Chick Embryo; Dihydropyridines; Glycine; Heart; Heart Atria; Manganese; Myocardial Contraction; Myocardium; Organometallic Compounds | 1991 |
Pertussis toxin stimulation of catecholamine release from adrenal medullary chromaffin cells: mechanism may be by direct activation of L-type and G-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Dihydropyridines; Electric Conductivity; Membrane Potentials; Nifedipine; Pertussis Toxin; Verapamil; Virulence Factors, Bordetella | 1991 |
[Single calcium channels from the membranes of the adrenal medullary substance].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channels; Cattle; Cell Membrane; Dihydropyridines; In Vitro Techniques; Ion Channel Gating; Lipid Bilayers; Male; Membrane Lipids; Membrane Potentials; Membrane Proteins; Nifedipine; Solubility; Time Factors | 1991 |
Dihydropyridine-sensitive calcium channels from skeletal muscle. I. Roles of subunits in channel activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aniline Compounds; Animals; Calcium Channels; Dihydropyridines; Fluorescent Dyes; Immunoblotting; In Vitro Techniques; Liposomes; Membrane Potentials; Muscles; Precipitin Tests; Rabbits; Xanthenes | 1991 |
Different sensitivities to dihydropyridines of catecholamine release from cat and ox adrenals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Catecholamines; Cats; Cattle; Dihydropyridines; In Vitro Techniques; Isradipine; Male; Nitrendipine; Perfusion; Species Specificity | 1990 |
Permeation of Pb2+ through calcium channels: fura-2 measurements of voltage- and dihydropyridine-sensitive Pb2+ entry in isolated bovine chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channels; Cattle; Cell Membrane Permeability; Cell Separation; Dihydropyridines; Fura-2; Lead; Membrane Potentials; Nifedipine | 1991 |
Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Isradipine; Male; Myocardium; Potassium; Pyrroles; Radioligand Assay; Rats; Vasoconstriction; Verapamil | 1991 |
Steady-state currents through voltage-dependent, dihydropyridine-sensitive Ca2+ channels in GH3 pituitary cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Electric Conductivity; Electrophysiology; Isradipine; Membrane Potentials; Pituitary Neoplasms; Rats | 1991 |
Voltage dependent calcium channels in cerebellar granule cell primary cultures.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channels; Cells, Cultured; Cerebellum; Dihydropyridines; Electrophysiology | 1991 |
Regulation of single calcium channels in cerebral arteries by voltage, serotonin, and dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Basilar Artery; Calcium; Calcium Channels; Dihydropyridines; Electric Conductivity; Electrophysiology; Ion Channel Gating; Nimodipine; Rabbits; Serotonin | 1991 |
The effect of dihydropyridine calcium channel agents on 5-HT metabolism in the CNS of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Central Nervous System; Dihydropyridines; Drug Interactions; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Inhibition of T-type calcium currents by dihydropyridines in mouse embryonic dorsal root ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Electric Conductivity; Electric Stimulation; Electrophysiology; Ganglia, Spinal; Mice; Neurons; Nicardipine | 1991 |
Phorbol esters induce oscillatory contractions of intestinal smooth muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Bradykinin; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Parasympatholytics; Parasympathomimetics; Phorbol Esters; Potassium Chloride; Protein Kinase C | 1991 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Thermodynamic and kinetic aspects of agonist and antagonist binding to 1,4-dihydropyridine receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Isradipine; Kinetics; Male; Membranes; Muscles; Myocardium; Nicotinic Antagonists; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Thermodynamics; Tritium | 1991 |
Modulation of electrical activity and of intracellular calcium oscillations of smooth muscle cells by calcium antagonists, agonists, and vasopressin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Isradipine; Membrane Potentials; Muscle, Smooth, Vascular; Rats; Vasopressins | 1991 |
The beta-adrenergic receptor-regulated 1,4-dihydropyridine calcium channel receptor sites in coronary artery smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cell Membrane; Cyclic AMP; Dihydropyridines; Dogs; Guanosine Triphosphate; Isoproterenol; Isradipine; Male; Microsomes; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta | 1991 |
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats | 1985 |
The calcium agonists Bay K 8644 and (+)202,791 stimulate the release of endothelial relaxing factor from canine femoral arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Dihydropyridines; Dogs; Endothelium; Femoral Artery; In Vitro Techniques; Ion Channels; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Pyridines | 1985 |
The effect of dihydropyridine calcium agonists and antagonists on neuronal voltage sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Brain Chemistry; Calcium; Calcium Channel Blockers; Cell Line; Dihydropyridines; Electric Stimulation; Glioma; In Vitro Techniques; Ion Channels; Neuroblastoma; Neurons; Nifedipine; Potassium; Pyridines; Rats; Synaptosomes; Verapamil | 1986 |
Purified calcium channels have three allosterically coupled drug receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1986 |
Ca2+-channel current and its modification by the dihydropyridine agonist BAY k 8644 in isolated smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Barium Compounds; Cell Membrane; Cesium; Chlorides; Dihydropyridines; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth; Nifedipine; Pyridines | 1986 |
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium; Cell Differentiation; Dihydropyridines; Nerve Growth Factors; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Secretory Rate | 1986 |
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pyridines; Rats | 1986 |
o-Isothiocyanate dihydropyridine (oNCS-DHP), a long-acting, reversible inhibitor of the Ca++ channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Drug Stability; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Heart; In Vitro Techniques; Isothiocyanates; Kinetics; Muscle Contraction; Nifedipine; Tritium | 1986 |
Widespread distribution of dihydropyridine-sensitive calcium channels in the central nervous system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Cells, Cultured; Cytosol; Dihydropyridines; Hippocampus; Ion Channels; Mice; Mice, Inbred C57BL; Neurons; Organ Specificity; Pyridines; Rats; Rats, Inbred Strains | 1986 |
Calcium agonists and antagonists of the dihydropyridine type: antinociceptive effects, interference with opiate-mu-receptor agonists and neuropharmacological actions in rodents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Calcium Channel Blockers; Dihydropyridines; Female; Motor Activity; Pain Measurement; Postural Balance; Pyridines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1986 |
BAY k 8644, a calcium channel agonist, reverses hypotension in endotoxin-shocked rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Male; Microsomes; Myocardium; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Shock, Septic | 1986 |
The effects of the cardiotonic dihydropyridine derivatives Bay k 8644 and H160/51 on post-rest adaptation of guinea-pig papillary muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adaptation, Physiological; Animals; Cardiotonic Agents; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Pyridines | 1986 |
Blockade of Ca2+ and K+ currents in bag cell neurons of Aplysia californica by dihydropyridine Ca2+ antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aplysia; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Kinetics; Mathematics; Neurons; Nifedipine; Nisoldipine; Potassium; Pyridines | 1987 |
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1987 |
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Cerebral Cortex; Dihydropyridines; Hydroxydopamines; In Vitro Techniques; Inositol Phosphates; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Sugar Phosphates; Vas Deferens | 1987 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
Analysis of the properties of binding of calcium-channel activators and inhibitors to dihydropyridine receptors in chick heart membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cations, Divalent; Chickens; Dihydropyridines; Ion Channels; Kinetics; Ligands; Membranes; Myocardium; Pyridines; Receptors, Cell Surface; Temperature | 1987 |
BAY K 8644 increases release of acetylcholine at the murine neuromuscular junction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Dihydropyridines; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neuromuscular Junction; Nimodipine; Rats; Rats, Inbred Strains | 1987 |
Regional distribution of calcium channel ligand (1,4-dihydropyridine) binding sites and 45Ca2+ uptake processes in rat brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channels; Caudate Nucleus; Cell Membrane; Cerebellum; Cerebral Cortex; Dihydropyridines; Hippocampus; Male; Nimodipine; Olfactory Bulb; Potassium; Rats; Receptors, Nicotinic; Synaptosomes; Tissue Distribution | 1987 |
Altered characteristics of catecholamine release from rat cortical slices and bovine adrenal chromaffin cells in culture after chronic exposure to ethanol and the effect of the dihydropyridine drugs on these systems.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Cerebral Cortex; Chromaffin System; Corpus Striatum; Dihydropyridines; Ethanol; Nitrendipine; Rats | 1987 |
Central interactions between dihydropyridines and cholinergic systems in the control of blood pressure in rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Atropine Derivatives; Blood Pressure; Cerebral Ventricles; Dihydropyridines; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Hippocampus; In Vitro Techniques; Male; Nicardipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Reference Values; Species Specificity | 1987 |
Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Chick Embryo; Dihydropyridines; Electric Stimulation; Ganglia, Spinal; Nifedipine; Substance P | 1988 |
Modulation of neurotransmitter metabolism by dihydropyridine calcium channel ligands in mouse brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dihydropyridines; Dopamine; Drug Interactions; Homovanillic Acid; Hydroxyindoleacetic Acid; Ion Channels; Male; Mice; Neurotransmitter Agents; Nifedipine | 1988 |
Interaction between Bay-K-8644 and various relaxant agents on K+-depolarized contracture of guinea pig taenia coli.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Colon; Dihydropyridines; Diltiazem; Ethanol; Gallopamil; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth; Nifedipine; Papaverine; Potassium | 1988 |
Effects of Bay k 8644 on the coronary vascular selectivity of the dihydropyridine Ca antagonists in the canine isolated, blood-perfused papillary muscle preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Dogs; In Vitro Techniques; Infusions, Intra-Arterial; Papillary Muscles; Vasodilation | 1987 |
Pharmacological characterization of two calcium currents in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Dihydropyridines; Electrophysiology; Ion Channels; Nitrendipine; Osmolar Concentration; Pituitary Gland; Rats | 1988 |
Calcium currents, charge movement and dihydropyridine binding in fast- and slow-twitch muscles of rat and rabbit.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Rabbits; Rats; Time Factors | 1987 |
Voltage-sensitive calcium channels in differentiated neuroblastoma X glioma hybrid (NG108-15) cells: characterization by quin 2 fluorescence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Bucladesine; Calcium; Cricetinae; Dihydropyridines; Fluorescent Dyes; Glioma; Humans; Hybrid Cells; Ion Channels; Membrane Potentials; Neuroblastoma; Potassium Chloride; Sodium; Tetrodotoxin; Veratridine | 1988 |
Morphine withdrawal in cortical slices: suppression by Ca2+-channel inhibitors of abstinence-induced [3H]-noradrenaline release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cerebral Cortex; Dihydropyridines; Disease Models, Animal; In Vitro Techniques; Ion Channels; Morphine; Naloxone; Nimodipine; Norepinephrine; Rats; Substance Withdrawal Syndrome; Tritium | 1988 |
Potassium depolarization elevates cytosolic free calcium concentration in rat anterior pituitary cells through 1,4-dihydropyridine-sensitive, omega-conotoxin-insensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Cytosol; Dihydropyridines; Fluorescent Dyes; Fura-2; Ion Channels; Magnesium; Male; Membrane Potentials; Mollusk Venoms; omega-Conotoxins; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains | 1988 |
The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Calcium; Cell Membrane; Cholera Toxin; Cyclic AMP; Dihydropyridines; Electric Conductivity; Erythrocytes; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Ion Channels; Lipid Bilayers; Muscles; Myocardium; Phosphorylation; Protein Kinases; Thionucleotides | 1988 |
Altered effect of BAY K 8644 after exposure of the rat aorta to IBMX or Db cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Bucladesine; Cyclic AMP; Dihydropyridines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Theophylline | 1988 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Central modulation of baroreceptor reflex response to phenylephrine by dihydropyridines in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine Derivatives; Blood Pressure; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Isradipine; Male; Muscarine; Oxadiazoles; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Reflex | 1988 |
Characterization of dihydropyridine-sensitive calcium channels in rat brain synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Centrifugation, Density Gradient; Dihydropyridines; Dopamine; Ion Channels; Potassium Chloride; Rats; Synaptosomes | 1988 |
[Central control of the baroreflex response to phenylephrine by dihydropyridines in the anesthetized rat].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium; Calcium Channels; Dihydropyridines; Heart Rate; Hypertension; Nifedipine; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Nicotinic; Sympathetic Nervous System | 1988 |
Direct coupling of a G-protein to dihydropyridine binding sites.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cerebral Cortex; Dihydropyridines; GTP-Binding Proteins; Guanosine Triphosphate; Male; Pertussis Toxin; Protein Binding; Rats; Rats, Inbred Strains; Synaptic Membranes; Virulence Factors, Bordetella | 1988 |
Dihydropyridine-sensitive calcium channel activity related to prolactin, growth hormone, and luteinizing hormone release from anterior pituitary cells in culture: interactions with somatostatin, dopamine, and estrogens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Dopamine; Estradiol; Female; Growth Hormone; Luteinizing Hormone; Male; Nitrendipine; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Potassium; Prolactin; Rats; Rats, Inbred Strains; Sex Characteristics; Somatostatin | 1988 |
Activation of dihydropyridine-sensitive calcium channels and biphasic cytosolic calcium responses by angiotensin II in rat adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium; Calcium Channels; Cattle; Cytosol; Dihydropyridines; Ethers; Ionomycin; Kinetics; Male; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Species Specificity; Spectrometry, Fluorescence; Zona Glomerulosa | 1988 |
Regulation of voltage-dependent excitatory responses to alpha,beta-methylene ATP, ATP and non-adrenergic nerve stimulation by dihydropyridines in the guinea-pig vas deferens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adenosine Triphosphate; Adrenergic Fibers; Animals; Calcium; Calcium Channels; Dihydropyridines; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Nifedipine; Vas Deferens | 1988 |
Secretion from adrenaline- and noradrenaline-storing adrenomedullary cells is regulated by a common dihydropyridine-sensitive calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium; Calcium Channel Blockers; Cats; Dihydropyridines; Dimethylphenylpiperazinium Iodide; Epinephrine; In Vitro Techniques; Ion Channels; Isradipine; Norepinephrine; Oxadiazoles; Potassium; Reference Values | 1988 |
Reduction of K+-stimulated 45Ca2+ influx in synaptosomes with age involves inactivating and noninactivating calcium channels and is correlated with temporal modifications in protein dephosphorylation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Dihydropyridines; Kinetics; Male; Molecular Weight; Nifedipine; Phosphoproteins; Phosphorylation; Potassium; Rats; Rats, Inbred Strains; Synaptosomes | 1989 |
Evidence that prejunctional adenosine receptors regulating acetylcholine release from rat hippocampal slices are linked to an N-ethylmaleimide-sensitive G-protein, but not to adenylate cyclase or dihydropyridine-sensitive Ca2+-channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Animals; Calcium Channel Blockers; Carrier Proteins; Cyclic AMP; Dihydropyridines; Electric Stimulation; Ethylmaleimide; GTP-Binding Proteins; Hippocampus; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Neurotransmitter; Receptors, Purinergic | 1988 |
Bone remodeling signaled by a dihydropyridine- and phenylalkylamine-sensitive calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bone Development; Bone Resorption; Calcium; Calcium Channels; Calcium-Binding Proteins; Cells, Cultured; Dihydropyridines; Electric Conductivity; Osteoblasts; Osteocalcin; Parathyroid Hormone; Rats; Receptors, Nicotinic; Stereoisomerism | 1989 |
Endothelin increases single-channel calcium currents in coronary arterial smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Coronary Vessels; Dihydropyridines; Electric Conductivity; Endothelins; Endothelium, Vascular; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Peptides; Second Messenger Systems; Swine | 1989 |
Homologous regulation of voltage-dependent calcium channels by 1,4-dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Cell Line; Dihydropyridines; Kinetics; Membrane Potentials; Pheochromocytoma; Radioligand Assay; Rats; Receptors, Nicotinic | 1989 |
Evidence for a dihydropyridine-sensitive and conotoxin-insensitive release of noradrenaline and uptake of calcium in adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Alprostadil; Animals; Brain Chemistry; Calcium; Calcium Radioisotopes; Cattle; Chromaffin System; Conotoxins; Corpus Striatum; Dihydropyridines; Dopamine; In Vitro Techniques; Mollusk Venoms; Norepinephrine; Potassium | 1989 |
Serotonin modulates calcium-dependent plateau of action potentials recorded from bull frog A-type sensory neurons which is omega-conotoxin GVIA-sensitive, but dihydropyridine-insensitive.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Dihydropyridines; Ganglia, Spinal; In Vitro Techniques; Mollusk Venoms; Neurons, Afferent; Nifedipine; omega-Conotoxin GVIA; Rana catesbeiana; Serotonin; Tetraethylammonium Compounds | 1989 |
Effects of dihydropyridine drugs on reversal by imipramine of helpless behavior in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Avoidance Learning; Dihydropyridines; Dose-Response Relationship, Drug; Electroshock; Helplessness, Learned; Imipramine; Male; Nimodipine; Rats; Rats, Inbred Strains | 1989 |
A dihydropyridine calcium channel blocker with phosphodiesterase inhibitory activity: effects on cultured vascular smooth muscle and cultured heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick Embryo; Depression, Chemical; Dihydropyridines; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Phosphodiesterase Inhibitors; Rats; Verapamil | 1988 |
Calcium uptake studies of 1,4-dihydropyridine agonists into rabbit aortic smooth muscle cells in culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Potassium; Pyridines; Rabbits | 1989 |
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil | 1989 |
PD 122860: a novel dihydropyridine with sodium channel stimulating and calcium channel blocking properties.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Colforsin; Coronary Circulation; Dihydropyridines; Electrocardiography; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Rats; Rats, Inbred Strains; Reference Values; Sodium Channels; Veratridine | 1989 |
Effects of Bay K 8644 on spontaneous and evoked transmitter release at the mouse neuromuscular junction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Dihydropyridines; Electric Stimulation; Female; In Vitro Techniques; Mice; Neuromuscular Junction; Phrenic Nerve; Time Factors | 1989 |
Contribution of external and internal Ca2+ to changes in intracellular free Ca2+ produced by mitogens in Swiss 3T3 fibroblasts: the role of dihydropyridine sensitive Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cell Line; Cytosol; Dihydropyridines; Extracellular Space; Fibroblasts; Mice; Mitogens; Nifedipine; Platelet-Derived Growth Factor | 1989 |
Photoaffinity labeling with dihydropyridine derivatives of crude membranes from rat skeletal, cardiac, ileal, and uterine muscles and whole brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Autoradiography; Brain; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Female; Ileum; In Vitro Techniques; Male; Membranes; Muscle, Smooth; Muscles; Myocardium; Nitrendipine; Rats; Spectrometry, Fluorescence; Uterus | 1989 |
Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Calcium Channels; Dihydropyridines; DNA; Electric Conductivity; Female; Gene Expression Regulation; Molecular Sequence Data; Molecular Weight; Muscles; Myocardium; Oocytes; Rabbits; Receptors, Nicotinic; RNA, Messenger; Sequence Homology, Nucleic Acid; Xenopus | 1989 |
Induction of calcium currents by the expression of the alpha 1-subunit of the dihydropyridine receptor from skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Calcium Channels; Cloning, Molecular; Dihydropyridines; DNA; Electric Conductivity; Gene Expression Regulation; Immunoblotting; L Cells; Macromolecular Substances; Mice; Molecular Weight; Muscles; Receptors, Nicotinic; Transfection; Transformation, Genetic | 1989 |
Effects of dihydropyridine calcium channel ligands on rat brain gamma-aminobutyric acidB receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Binding, Competitive; Calcium Channels; Dihydropyridines; Male; Nifedipine; Rats; Receptors, GABA-A | 1989 |
Nonmodal gating of cardiac calcium channels as revealed by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channels; Cells, Cultured; Dihydropyridines; Electrophysiology; Guinea Pigs; Myocardium; Rats | 1989 |
Calcium currents in single isolated smooth muscle cells from the rabbit ear artery in normal-calcium and high-barium solutions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Dihydropyridines; Ear; Electric Conductivity; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Rabbits | 1988 |
Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Captopril; Dihydropyridines; Dogs; Endothelins; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Peptides; Rabbits | 1989 |
Dihydropyridines modulate K+-evoked amino acid and adenosine release from cerebellar neuronal cultures.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Amino Acids; Animals; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Dihydropyridines; Potassium; Rats; Verapamil | 1989 |
Molecular properties of voltage-activated calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Azides; Calcium Channels; Cloning, Molecular; Dihydropyridines; DNA; Glycoproteins; Muscles; Phosphorylation; Protein Conformation; Protein Kinases; Receptors, Nicotinic; Verapamil | 1989 |
Interaction between isoproterenol and dihydropyridines in heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Isoproterenol; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Time Factors | 1989 |
Calcium currents in bullfrog sympathetic neurons. I. Activation kinetics and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Cadmium; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Ganglia, Sympathetic; Kinetics; Membrane Potentials; Neurons; Nifedipine; Rana catesbeiana; Saxitoxin; Second Messenger Systems | 1989 |
Slow onset of and recovery from Ca blocking action of benidipine in rat aorta and portal vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Calcium Channel Blockers; Dihydropyridines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Portal Vein; Rats; Rats, Inbred Strains | 1989 |
The response of single cardiac sodium channels in neonatal rats to the dihydropyridines CGP 28392 and (-)-Bay K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Cell Membrane; Cytoplasm; Dihydropyridines; Ethanol; Heart; In Vitro Techniques; Male; Myocardium; Pyridines; Rats; Sodium Channels | 1989 |
Modulation of solitarial deglutitive N-methyl-D-aspartate receptors by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Deglutition; Dihydropyridines; Electric Stimulation; Esophagus; Male; Medulla Oblongata; Microelectrodes; Pharynx; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Dihydropyridines; Membrane Potentials; Neurons; Potassium | 1989 |
Vitamin D3 metabolites modulate dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells.
Topics: 24,25-Dihydroxyvitamin D 3; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcifediol; Calcitriol; Calcium; Calcium Channels; Cell Line; Dihydropyridines; Kinetics; Membrane Potentials; Osteosarcoma; Rats; Tumor Cells, Cultured | 1989 |
Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic beta-cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Dihydropyridines; Electric Conductivity; Glucose; In Vitro Techniques; Islets of Langerhans; Membrane Potentials; Mice | 1989 |
The effects of dihydropyridine compounds in behavioural tests of dopaminergic activity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amphetamine; Animals; Apomorphine; Behavior, Animal; Dihydropyridines; Dopamine; Generalization, Psychological; Learning; Male; Medial Forebrain Bundle; Motor Activity; Penile Erection; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Yawning | 1989 |
Thyroliberin and dihydropyridines modulate prolactin gene expression through interacting pathways in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Gene Expression; Isradipine; Kinetics; Oxadiazoles; Pituitary Neoplasms; Prolactin; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1989 |
Actions and interactions of dihydropyridines and ethanol on the rat sinus node.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Atropine; Dihydropyridines; Drug Interactions; Ethanol; In Vitro Techniques; Male; Microelectrodes; Myocardial Contraction; Nimodipine; Rats; Rats, Inbred Strains; Sinoatrial Node | 1989 |
Dihydropyridine sensitive calcium channels in a smooth muscle cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Cobalt; Dihydropyridines; Ion Channels; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Pyridines; Rats | 1985 |
Cytokinin stimulates dihydropyridine-sensitive calcium uptake in moss protoplasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Biological Transport; Calcium; Calcium Channels; Cell Differentiation; Cells, Cultured; Dihydropyridines; In Vitro Techniques; Ion Channel Gating; Plant Cells; Plant Growth Regulators; Plant Physiological Phenomena; Potassium | 1993 |
PCA 50941, a novel Ca2+ channel agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium Channel Agonists; Cardiovascular System; Dihydropyridines; Heart Atria; In Vitro Techniques; Isradipine; Mesenteric Arteries; Muscles; Nitrendipine; Rabbits; Rats; Rats, Sprague-Dawley; Swine; Thiazoles; Vasoconstriction | 1993 |
Influence of dihydropyridine-type calcium agonists on hemodynamics and myocardial ischemia in isolated rabbit hearts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Coronary Circulation; Dihydropyridines; Fluorescence; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; NAD; Ouabain; Rabbits; Ventricular Function, Left | 1993 |
The nicotinic acetylcholine receptor of the bovine chromaffin cell, a new target for dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Radioisotopes; Catecholamines; Cattle; Cytosol; Dihydropyridines; Dimethylphenylpiperazinium Iodide; Electrophysiology; Enterochromaffin Cells; Fura-2; Manganese; Membrane Potentials; Nimodipine; Potassium; Receptors, Cholinergic | 1993 |
"Stimulation of dihydropyridine-sensitive Ca2+ influx in cultured myoblasts by 1,25(OH)2-vitamin D3".
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcitriol; Calcium Channels; Cells, Cultured; Chick Embryo; Dihydropyridines; Egtazic Acid; Muscles; Nifedipine; Rats; Rats, Wistar | 1993 |
Dihydropyridine-sensitive initial component of the ANG II-induced Ca2+ response in rat adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium; Calcium Channels, L-Type; Dihydropyridines; Female; Manganese; Membrane Potentials; Muscle Proteins; Nifedipine; Potassium; Rats; Rats, Wistar; Zona Glomerulosa | 1994 |
Endogenous ganglioside GM1 modulates L-type calcium channel activity in N18 neuroblastoma cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Cholera Toxin; Dihydropyridines; Egtazic Acid; Fura-2; G(M1) Ganglioside; G(M3) Ganglioside; Manganese; Mice; Microscopy, Fluorescence; Neuroblastoma; Nicardipine; Nickel; Potassium; Tumor Cells, Cultured | 1994 |
Left ventricular mechanical consequences of dihydropyridine calcium channel modulation in conscious and anesthetized chronically instrumented dogs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Anesthetics; Animals; Autonomic Nerve Block; Autonomic Nervous System; Calcium Channels; Consciousness; Diastole; Dihydropyridines; Dogs; Drug Interactions; Halothane; Hemodynamics; Isoflurane; Myocardial Contraction; Nifedipine; Systole; Ventricular Function, Left | 1994 |
Epithelial Ca2+ channels sensitive to dihydropyridines and activated by hyperpolarizing voltages.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; Electrophysiology; Epithelial Cells; Epithelium; Kidney Tubules, Distal; Mice; Parathyroid Hormone | 1994 |
Effects of nifedipine and Bay K 8644 on contractile activities in single skeletal muscle fibers of the frog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Adenine; Animals; Caffeine; Calcium; Cell Membrane; Dihydropyridines; Electric Stimulation; Electrophysiology; In Vitro Techniques; Microelectrodes; Muscle Contraction; Muscles; Nifedipine; Potassium; Xenopus laevis | 1994 |
Endogenous DHP-sensitive Ca(2+) channels in Pleurodeles oocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Dihydropyridines; Membrane Potentials; Mollusk Venoms; Nifedipine; omega-Conotoxin GVIA; Oocytes; Peptides; Pleurodeles | 1994 |
Ethanol directly modulates gating of a dihydropyridine-sensitive Ca2+ channel in neurohypophysial terminals.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; Electrophysiology; Ethanol; Ion Channel Gating; Nerve Endings; Pituitary Gland, Posterior; Rats; Rats, Inbred Strains | 1994 |
Omega 3 polyunsaturated fatty acid modulates dihydropyridine effects on L-type Ca2+ channels, cytosolic Ca2+, and contraction in adult rat cardiac myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arachidonic Acid; Calcium; Calcium Channels; Dihydropyridines; Docosahexaenoic Acids; Fatty Acids, Omega-3; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta | 1994 |
Comparative effects of the dihydropyridine-type calcium-agonists (-)-S-Bay K 8644, (+/-)-Bay-W 5035 and (+/-)-Bay-T 5006 on human platelet aggregability.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channel Agonists; Cardiovascular System; Dihydropyridines; Humans; Molecular Structure; Nicotinic Acids; Platelet Aggregation Inhibitors; Pyridazines; Structure-Activity Relationship | 1994 |
Calcium channel subtypes in cat chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Barium; Calcium Channels; Cats; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Female; Ion Channel Gating; Male; Membrane Potentials; Nisoldipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides | 1994 |
Cadmium uptake by kidney distal convoluted tubule cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analysis of Variance; Animals; Cadmium; Calcium; Calcium Channels; Cations, Divalent; Cell Line, Transformed; Dihydropyridines; Kidney Tubules, Distal; Mice; Nifedipine; Parathyroid Hormone | 1994 |
Temperature dependence of multiple high voltage activated Ca2+ channels in chick sensory neurones.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Chick Embryo; Dihydropyridines; Electrochemistry; Ganglia, Spinal; Neurons, Afferent; omega-Conotoxin GVIA; Peptides; Sensitivity and Specificity; Temperature | 1994 |
Interactions between Ca2+, PCA50941 and Bay K 8644 in bovine chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Catecholamines; Cattle; Cell Membrane; Cytosol; Dihydropyridines; Fura-2; In Vitro Techniques; Isradipine; Patch-Clamp Techniques; Potassium; Thiazoles | 1994 |
Identification of dihydropyridine (DHP) binding sites on cultured monkey renal cells (GMRC) with a photoaffinity probe (-)-[3H]-azidopine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Azides; Binding Sites; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chlorocebus aethiops; Dihydropyridines; Kidney; Kinetics; Muscle Proteins; Nisoldipine; Nitrendipine; Propanolamines; Receptors, Adrenergic, beta | 1994 |
Inhibition of dihydropyridine-sensitive calcium entry in hypoxic relaxation of airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bronchi; Calcium; Calcium Channel Blockers; Carbachol; Dihydropyridines; Female; Hypoxia; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Potassium Chloride; Swine | 1995 |
Single-channel properties of four calcium channel types in rat motoneurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channels; Dihydropyridines; Hypoglossal Nerve; Motor Neurons; Nerve Tissue Proteins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Spider Venoms | 1995 |
Evidence that TRH controls prolactin release from rat lactotrophs by stimulating a calcium influx.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channels; Cells, Cultured; Culture Media; Cytoplasm; Dihydropyridines; Female; Nifedipine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Thyrotropin-Releasing Hormone | 1994 |
Modulation of the dihydropyridine-insensitive Ca2+ influx by 8-bromo-guanosine-3':5'-monophosphate, cyclic (8-Br-cGMP) in bovine adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Bucladesine; Calcium; Calcium Channels; Cattle; Cells, Cultured; Cyclic GMP; Dihydropyridines; Neomycin; Nerve Tissue Proteins; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Potassium Chloride; Second Messenger Systems; Spider Venoms | 1994 |
Single calcium channel behavior in native skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium Compounds; Cadmium; Cadmium Chloride; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chlorides; Dihydropyridines; Electrophysiology; Isradipine; Lanthanum; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Patch-Clamp Techniques | 1995 |
Involvement of different types of voltage-sensitive calcium channels in the presynaptic regulation of noradrenaline release in rat brain cortex and hippocampus.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Dihydropyridines; Electrophysiology; Hippocampus; Male; Norepinephrine; omega-Conotoxin GVIA; Peptides; Presynaptic Terminals; Rats; Rats, Sprague-Dawley | 1995 |
Boar sperm plasma membrane Ca(2+)-selective channels in planar lipid bilayers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cell Membrane; Dihydropyridines; Electrophysiology; Lipid Bilayers; Male; Nitrendipine; Spermatozoa; Stereoisomerism; Swine | 1995 |
In vivo labelling of L-type Ca2+ channels by fluorescent dihydropyridine: correlation between ontogenesis of the channels and the acquisition of neural competence in ecotderm cells from Pleurodeles waltl embryos.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blastocyst; Boron Compounds; Calcium; Calcium Channels; Calcium Channels, L-Type; Cell Differentiation; Dihydropyridines; Ectoderm; Fluorescent Dyes; Gastrula; Microscopy, Fluorescence; Pleurodeles | 1995 |
Voltage-dependent calcium channel beta-subunits in combination with alpha 1 subunits, have a GTPase activating effect to promote the hydrolysis of GTP by G alpha o in rat frontal cortex.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Binding Sites; Calcium Channels; Cell Membrane; Dihydropyridines; Enzyme Activation; Frontal Lobe; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Peptide Fragments; Rats | 1995 |
[Calcium channels in bullfrog saccular hair cells].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dihydropyridines; Hair Cells, Vestibular; Membrane Potentials; Nifedipine; Patch-Clamp Techniques; Rana catesbeiana | 1995 |
Multiple calcium channel subtypes in isolated rat chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cells, Cultured; Dihydropyridines; Female; Ion Channel Gating; Ion Transport; Male; Membrane Potentials; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Species Specificity; Spider Venoms | 1995 |
Effects of the novel water-soluble calcium antagonist (+/-)-3-(4-allyl-1-piperazinyl)-2,2-dimethylpropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate dihydrochloride on the responses of isolated canine arteries.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Dogs; Female; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Potassium Chloride; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Identification of a novel calcium antagonist binding site in rat brain by SR 33557.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channel Blockers; Cations, Divalent; Cations, Monovalent; Cecum; Cerebral Cortex; Dihydropyridines; Female; Guinea Pigs; Indolizines; Male; Muscle Contraction; Muscle, Smooth; Phenethylamines; Rats; Rats, Sprague-Dawley | 1993 |
Effects of nifedipine and Bay-K-8644 on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Anesthesia; Animals; Calcium Channels; Dihydropyridines; Dogs; Electric Stimulation; Epinephrine; Female; Male; Nifedipine; Norepinephrine; Sensitivity and Specificity; Splanchnic Nerves | 1993 |
Dihydropyridine-sensitive calcium channels expressed in canine colonic smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Base Sequence; Calcium Channels; Cells, Cultured; Colon; Dihydropyridines; Dogs; Female; Ion Channel Gating; Male; Membrane Potentials; Molecular Sequence Data; Muscle, Smooth; Nifedipine; Time Factors | 1993 |
A component of the catecholamine secretory response in the bovine adrenal gland is resistant to dihydropyridines and omega-conotoxin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Glands; Animals; Calcium; Calcium Channel Blockers; Catecholamines; Cattle; Dihydropyridines; In Vitro Techniques; Mollusk Venoms; Nisoldipine; omega-Conotoxins; Peptides, Cyclic; Potassium; Secretory Rate | 1993 |
Modulation of calcium channels in arterial smooth muscle cells by dihydropyridine enantiomers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; In Vitro Techniques; Membrane Potentials; Muscle, Smooth, Vascular; Rabbits; Stereoisomerism | 1993 |
The properties of voltage-operated Ca(2+)-channels in bovine isolated trachealis cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channels; Cattle; Cell Membrane; Dihydropyridines; Electrophysiology; In Vitro Techniques; Muscle, Smooth; Nifedipine; Rats; Trachea | 1993 |
Re-evaluation of calcium currents in pre- and postsynaptic neurones of the chick ciliary ganglion.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channels; Calcium-Transporting ATPases; Chick Embryo; Ciliary Body; Dihydropyridines; Ion Pumps; Ions; Membrane Potentials; Mollusk Venoms; Nifedipine; omega-Conotoxin GVIA; Schwann Cells; Synapses | 1993 |
Dihydropyridine-sensitive calcium current mediates neurotransmitter release from bipolar cells of the goldfish retina.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Fura-2; Goldfish; In Vitro Techniques; Kinetics; Neurons; Nicardipine; Nifedipine; omega-Conotoxins; Peptides; Retina | 1993 |
[Single channel analysis of Ca2+ channel-agonistic action of dihydropyridine derivatives: voltage-dependent effects of YC-170 and BAY K 8644].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Membrane Potentials; Myocardium; Nifedipine; Rabbits | 1993 |
Effect of low-density lipoproteins, mevinolin, and G proteins on Ca2+ response in cultured chick atrial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cattle; Cells, Cultured; Chick Embryo; Dihydropyridines; Extracellular Space; Fetal Blood; GTP-Binding Proteins; Heart Atria; Lipoproteins, LDL; Lovastatin; Myocardium; Pertussis Toxin; Virulence Factors, Bordetella | 1993 |
Sensitivity to dihydropyridines, omega-conotoxin and noradrenaline reveals multiple high-voltage-activated Ca2+ channels in rat insulinoma and human pancreatic beta-cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophysiology; Humans; Insulinoma; Islets of Langerhans; Norepinephrine; omega-Conotoxin GVIA; Pancreatic Neoplasms; Peptides; Rats; Tumor Cells, Cultured | 1993 |
Two high-voltage-activated, dihydropyridine-sensitive Ca2+ channel currents with distinct electrophysiological and pharmacological properties in cultured rat aortic myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Barium; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Electric Conductivity; Electrophysiology; Male; Muscle, Smooth, Vascular; Nicardipine; Rats; Rats, Wistar | 1993 |
Influence of (-)-S-Bay K 8644, (+/-)-Bay W 5035 and (+/-)-Bay T 5006 on hemodynamics and FITC-dextran 3 elution kinetics in isolated rat hearts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Blood Volume; Calcium Channel Agonists; Coronary Circulation; Dextrans; Dihydropyridines; Fluorescein-5-isothiocyanate; Half-Life; Heart; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Nicotinic Acids; Perfusion; Pyridazines; Rats; Rats, Wistar; Stereoisomerism | 1993 |
MPC-1304, another type of dihydropyridine, possessing highly potent vasodilating action.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Muscle Proteins; Rats; Rats, Inbred SHR; Rats, Wistar; Swine; Vasodilation; Vasodilator Agents | 1993 |
Estradiol modulation of GNRH-stimulated LH release in rat anterior pituitary cells: involvement of dihydropyridine-sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Estradiol; Female; Gallopamil; Gonadotropin-Releasing Hormone; Isradipine; Luteinizing Hormone; Ovariectomy; Pituitary Gland, Anterior; Protein Kinase C; Radioimmunoassay; Rats; Rats, Wistar | 1993 |
Blockade by funnel web toxin of a calcium current in the intermediate pituitary of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Ion Channel Gating; Male; Mollusk Venoms; Nickel; Peptides; Pituitary Gland; Polyamines; Rats; Rats, Sprague-Dawley; Spider Venoms | 1993 |
The involvement of dihydropyridine-sensitive calcium channels in phorbol ester-induced luteinizing hormone and growth hormone release.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Calcium Channels; Dihydropyridines; Female; Growth Hormone; Ion Channel Gating; Isoquinolines; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Staurosporine | 1993 |
Effects of cerebral ischemia on N-methyl-D-aspartate and dihydropyridine-sensitive calcium currents. An electrophysiological study in the rat hippocampus in situ.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electric Impedance; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Agonists; Hippocampus; Ion Channels; Iontophoresis; Ischemic Attack, Transient; Male; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion | 1996 |
Extracellular heparin inhibits Ca2+ transients and contraction in mammalian cardiac myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Extracellular Space; Fura-2; Glycosaminoglycans; Guinea Pigs; Heparin; In Vitro Techniques; Myocardial Contraction; Myocardium; Papillary Muscles; Rats | 1995 |
Negative inotropic action of denbufylline through interfering with the calcium channel independently of its PDE IV inhibitory activity in guinea pig ventricle papillary muscles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azides; Caffeine; Calcium Channels; Depression, Chemical; Dihydropyridines; Guinea Pigs; In Vitro Techniques; Isoquinolines; Male; Myocardial Contraction; Papillary Muscles; Phosphodiesterase Inhibitors; Ryanodine; Sulfonamides; Xanthines | 1996 |
Conotoxin-sensitive and conotoxin-resistant Ca2+ currents in fish retinal ganglion cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Agatoxins; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Goldfish; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Retinal Ganglion Cells; Spider Venoms | 1996 |
G proteins regulate dihydropyridine binding to moss plasma membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Binding Sites; Bryopsida; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; GTP-Binding Proteins; Guanine Nucleotides; Nifedipine | 1996 |
Regulation of angiotensin II-stimulated Ca2+ oscillations by Ca2+ influx mechanisms in adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium; Calcium Channels; Cattle; Dihydropyridines; Dose-Response Relationship, Drug; Evoked Potentials; Inositol Phosphates; Nifedipine; Terpenes; Thapsigargin; Zona Glomerulosa | 1996 |
Depolarization-evoked increases in cytosolic calcium concentration in isolated smooth muscle cells of rat portal vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cytophotometry; Cytosol; Dihydropyridines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nimodipine; Patch-Clamp Techniques; Portal Vein; Rats; Rats, Sprague-Dawley; Ryanodine; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Activation of nucleotide receptors inhibits high-threshold calcium currents in NG108-15 neuronal hybrid cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Hybrid Cells; Mice; Mollusk Venoms; Neuroblastoma; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Rats; Receptors, Cell Surface; Virulence Factors, Bordetella | 1996 |
Alpha 1-adrenergic activation inhibits beta-adrenergic-stimulated unitary Ca2+ currents in cardiac ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Calcium Channels; Dihydropyridines; Electric Conductivity; Kinetics; Myocardium; Protein Kinase C; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Ventricular Function | 1996 |
Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Binding Sites; Biophysical Phenomena; Biophysics; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; In Vitro Techniques; Ion Channel Gating; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nifedipine; Protein Conformation; Protein Structure, Secondary; Thermodynamics | 1996 |
AR4-2J cell line coexpresses dihydropyridine and omega-conotoxin sensitive Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antisense Elements (Genetics); Base Sequence; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Carcinoma; Cell Division; Dihydropyridines; DNA Primers; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Mollusk Venoms; Pancreas; Pancreatic Neoplasms; Polymerase Chain Reaction; Rats; Tumor Cells, Cultured | 1996 |
Dihydropyridine-sensitive and -insensitive voltage-operated calcium channels participate in the control of glucose-induced insulin release from human pancreatic beta cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mollusk Venoms; Nitrendipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides | 1996 |
Meiosis reinitiation in Ruditapes philippinarum (Mollusca): involvement of L-calcium channels in the release of metaphase I block.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bivalvia; Boron Compounds; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Dihydropyridines; Electrophysiology; Female; Fertilization in Vitro; Fluorescence; Isradipine; Male; Meiosis; Metaphase; Oocytes; Potassium Chloride; Prophase; Serotonin | 1996 |
Functional role of low-voltage-activated dihydropyridine-sensitive Ca channels during the action potential in adult rat sensory neurones.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Electric Conductivity; Electrophysiology; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Neurons, Afferent; Rats | 1996 |
Modulation of the cloned skeletal muscle L-type Ca2+ channel by anchored cAMP-dependent protein kinase.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels; Cloning, Molecular; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dichlororibofuranosylbenzimidazole; Dihydropyridines; Electric Conductivity; Membrane Proteins; Mice; Muscle, Skeletal; Phosphorylation; Thionucleotides | 1997 |
Effects of dihydropyridines on aldosterone secretion in adrenal capsule preparations from pregnant rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Animals; Calcium; Dihydropyridines; Dose-Response Relationship, Drug; Female; Osmolar Concentration; Potassium; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1997 |
A dihydropyridine-sensitive voltage-dependent calcium channel in the sarcolemmal membrane of crustacean muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Crustacea; Dihydropyridines; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Muscle Contraction; Muscle Fibers, Skeletal; Muscles; Patch-Clamp Techniques; Sarcolemma | 1997 |
Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dantrolene; Dihydropyridines; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Female; Isradipine; Lethal Dose 50; Mice; Motor Activity; Phenobarbital; Phenytoin; Random Allocation; Seizures; Valproic Acid | 1997 |
Depolarization and activation of dihydropyridine-sensitive Ca2+ channels stimulate inositol phosphate accumulation in photoreceptor-enriched chick retinal cell cultures.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chick Embryo; Dihydropyridines; Electric Stimulation; Estrenes; Inositol Phosphates; Membrane Potentials; Nifedipine; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphodiesterase Inhibitors; Photoreceptor Cells; Potassium; Pyrrolidinones; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Humans; Isradipine; Molecular Sequence Data; Mutagenesis, Site-Directed | 1997 |
L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Aorta; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Differentiation; Cell Line; Culture Media; Dihydropyridines; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nimodipine; Patch-Clamp Techniques; Rats; Tretinoin | 1998 |
PCA50941, a new 1,4-dihydropyridine, reverses endothelin-induced cardiogenic shock in the anesthetized goat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Agonists; Coronary Circulation; Dihydropyridines; Endothelin-1; Female; Goats; Heart; Heart Rate; Infusions, Intravenous; Shock, Cardiogenic; Thiazoles; Ventricular Function, Left | 1998 |
Voltage-gated calcium channels in Pleurodeles oocytes: classification, modulation and functional roles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breeding; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dihydropyridines; Electric Stimulation; Ion Channel Gating; Ion Transport; Meiosis; Membrane Potentials; Nickel; Nifedipine; omega-Conotoxin GVIA; Oocytes; Peptides; Phosphorylation; Pleurodeles; Progesterone; Protein Processing, Post-Translational; Seasons; Second Messenger Systems | 1998 |
Ca2+ channel modulation alters halothane-induced depression of ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Wistar; Sarcolemma; Verapamil | 1998 |
Isolation of a member of the neurotoxin/cytotoxin peptide family from Xenopus laevis skin which activates dihydropyridine-sensitive Ca2+ channels in mammalian epithelial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Amino Acid Sequence; Amphibian Venoms; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Guinea Pigs; Jejunum; Molecular Sequence Data; Neurotoxins; Peptides; Skin; Staurosporine; Xenopus laevis | 1998 |
Two types of calcium currents of the mouse bipolar cells recorded in the retinal slice preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cobalt; Dihydropyridines; Membrane Potentials; Mice; Mice, Inbred Strains; omega-Conotoxin GVIA; Organ Culture Techniques; Patch-Clamp Techniques; Peptides; Retina; Tetraethylammonium | 1998 |
L- and T-type voltage-gated Ca2+ currents in adrenal medulla endothelial cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cattle; Dihydropyridines; Electric Conductivity; Electrophysiology; Endothelium; Ion Channel Gating | 1999 |
Damaging effects of the calcium paradox are reduced in isolated hearts from ethanol-dependent rats: paradoxic effects of dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Calcium; Calcium Channel Blockers; Central Nervous System Depressants; Dihydropyridines; Ethanol; Heart; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardium; Nitrendipine; Perfusion; Rats; Rats, Sprague-Dawley | 1999 |
Role of neuropeptide-sensitive L-type Ca(2+) channels in histamine release in gastric enterochromaffin-like cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylate Cyclase Toxin; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; DNA Primers; Enterochromaffin-like Cells; Galanin; Gastric Acid; Gastric Mucosa; Gastrins; Gene Expression; GTP-Binding Proteins; Histamine; Histamine Release; Membrane Potentials; Neuropeptides; Neurotransmitter Agents; omega-Conotoxin GVIA; Peptide YY; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Rabbits; Rats; Receptors, Histamine H2; Somatostatin; Stomach; Tetraethylammonium; Virulence Factors, Bordetella | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression; Hippocampus; Ion Channel Gating; N-Methylaspartate; Phosphorylation; Pyramidal Cells; Rats | 2000 |
Dihydropyridine-sensitive calcium currents in bipolar cells of salamander retina are inhibited by reductions in extracellular chloride.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Ambystoma; Animals; Barium; Calcium Channels, L-Type; Chlorides; Dihydropyridines; Gluconates; In Vitro Techniques; Larva; Membrane Potentials; Nisoldipine; Nystatin; Patch-Clamp Techniques; Photoreceptor Cells, Vertebrate; Retina | 2000 |
Altered L-type Ca(2+) channel currents in vascular smooth muscle cells from experimental diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Bucladesine; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP; Diabetes Mellitus, Experimental; Dihydropyridines; Electric Conductivity; Glucose; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tail | 2000 |
Dihydropyridine-induced Ca2+ release from ryanodine-sensitive Ca2+ pools in human skeletal muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Dihydropyridines; Humans; Muscle, Skeletal; Nifedipine; Nitrendipine; PC12 Cells; Protein Conformation; Rats; Ryanodine; Ryanodine Receptor Calcium Release Channel | 2000 |
The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangium cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcimycin; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Carcinogens; Cells, Cultured; Dihydropyridines; Gene Expression; Genes, Reporter; Glomerular Mesangium; Humans; Ionophores; Luciferases; NF-kappa B; Nifedipine; Nitrophenols; Organophosphorus Compounds; Tetradecanoylphorbol Acetate; Verapamil | 2000 |
Hypotonic swelling increases L-type calcium current in smooth muscle cells of the human stomach.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Size; Cells, Cultured; Dihydropyridines; Electric Conductivity; Fluorometry; Gastric Mucosa; Humans; Hypotonic Solutions; Muscle, Smooth, Vascular; Osmotic Pressure; Patch-Clamp Techniques; Stomach | 2000 |
Gestational changes in uterine L-type calcium channel function and expression in guinea pig.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Female; Guinea Pigs; Isradipine; Molecular Sequence Data; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Uterine Contraction; Uterus | 2000 |
Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Electric Conductivity; Glutathione Transferase; GTP-Binding Proteins; Humans; Neurons; Protein Isoforms; Recombinant Fusion Proteins | 2001 |
Activation of purified cardiac ryanodine receptors by dihydropyridine agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Dogs; Membrane Potentials; Myocardium; Nicotinic Acids; Nifedipine; Oxadiazoles; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Stereoisomerism | 2001 |
Chronic nicotine alters NO signaling of Ca(2+) channels in cerebral arterioles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Barium; Calcium; Calcium Channels; Calcium Channels, L-Type; Cerebral Arteries; Cerebrovascular Circulation; Cyclic GMP; Dihydropyridines; Electric Stimulation; Female; Membrane Potentials; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Nitric Oxide; Nitroprusside; Potassium Channels; Rats; Rats, Inbred WKY; Signal Transduction; Time Factors; Tyrphostins | 2001 |
Abnormality of calcium channel inhibitor released from fetal membranes in preterm labor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Extraembryonic Membranes; Female; Guinea Pigs; Humans; Isradipine; Obstetric Labor, Premature; Organ Specificity; Placenta; Pregnancy; Random Allocation; Rats; Rats, Wistar; Uterine Contraction | 2001 |
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil | 2001 |
Parathyroid cells express dihydropyridine-sensitive cation currents and L-type calcium channel subunits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Blotting, Northern; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cattle; Cell Separation; Cloning, Molecular; Dihydropyridines; DNA; Electrophysiology; Immunohistochemistry; In Vitro Techniques; Ion Channels; Molecular Sequence Data; Parathyroid Glands; Parathyroid Hormone; Patch-Clamp Techniques; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alternative Splicing; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Kidney; Membrane Potentials; Molecular Sequence Data; Nimodipine; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Signal Transduction; Transfection; Xenopus | 2001 |
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Aorta; Blood Pressure; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiac Output; Consciousness; Dihydropyridines; Female; Heart Rate; Muscle, Smooth, Vascular; Nifedipine; Pregnancy; Pregnancy, Animal; Rabbits; Thromboxane B2; Tritium | 2002 |
Niguldipine impairs the protective activity of carbamazepine and phenobarbital in amygdala-kindled seizures in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amygdala; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dihydropyridines; Drug Combinations; Injections, Intraperitoneal; Kindling, Neurologic; Male; Phenobarbital; Rats; Rats, Wistar; Seizures | 2002 |
Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Colon; Dihydropyridines; Electrophysiology; In Vitro Techniques; Intestine, Small; Ion Channel Gating; Membrane Potentials; Mibefradil; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Muscle, Smooth; Nickel; Patch-Clamp Techniques; Sodium | 2002 |
Inhibitory effects of 1,4-DHP antagonists on synaptic GABA release modulated by BAY-K 8644 in mechanically dissociated rat substantia innominata.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channels, L-Type; Dihydropyridines; Electrophysiology; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Substantia Innominata; Synapses | 2002 |
Inhibition of cAMP signalling cascade-mediated Ca2+ influx by a prothoracicostatic peptide (Mas-MIP I) via dihydropyridine-sensitive Ca2+ channels in the prothoracic glands of the silkworm, Bombyx mori.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bombyx; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Dihydropyridines; Exocrine Glands; Kinetics; Larva; Signal Transduction | 2003 |
Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Cricetinae; Dihydropyridines; Electrophysiology; Enzyme Inhibitors; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rabbits; Serine; Threonine; Time Factors; Transfection | 2003 |
Biophysical and pharmacological characterization of voltage-gated calcium currents in turtle auditory hair cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Algorithms; Animals; Apamin; Barium; Biophysical Phenomena; Biophysics; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Dose-Response Relationship, Drug; Electrophysiology; Hair Cells, Auditory; Hearing; In Vitro Techniques; Ion Channel Gating; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Turtles | 2003 |
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction | 2003 |
Cav1.4alpha1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cloning, Molecular; Dihydropyridines; Humans; Ion Channel Gating; Isradipine; Kidney; Molecular Sequence Data; Patch-Clamp Techniques; Protein Subunits; Sequence Homology, Amino Acid; Transfection | 2003 |
L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Drug Interactions; Gene Expression Regulation; NAV1.2 Voltage-Gated Sodium Channel; NAV1.3 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Nimodipine; Nucleic Acid Amplification Techniques; Pituitary Gland; Protein Subunits; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sodium Channels; Up-Regulation | 2003 |
Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affect; Animals; Calcium Channels, L-Type; Cardiovascular Physiological Phenomena; Dihydropyridines; Islets of Langerhans; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Protein Isoforms | 2004 |
Intraglomerular inhibition: signaling mechanisms of an olfactory microcircuit.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Bicuculline; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Dendrites; Diagnostic Imaging; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Conduction; Neural Inhibition; Neural Networks, Computer; Neurons; Nickel; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phosphinic Acids; Potassium; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
The actions of azelnidipine, a dihydropyridine-derivative Ca antagonist, on voltage-dependent Ba2+ currents in guinea-pig vascular smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azetidinecarboxylic Acid; Barium; Calcium Channel Blockers; Dihydropyridines; Female; Guinea Pigs; Ion Channel Gating; Male; Muscle, Smooth, Vascular | 2006 |
Maturation of rat cerebellar Purkinje cells reveals an atypical Ca2+ channel current that is inhibited by omega-agatoxin IVA and the dihydropyridine (-)-(S)-Bay K8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebellar Cortex; Dihydropyridines; Male; Membrane Potentials; omega-Agatoxin IVA; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Wistar | 2007 |
Synthesis and docking studies of new 1,4-dihydropyridines containing 4-(5)-Chloro-2-ethyl-5-(4)-imidazolyl substituent as novel calcium channel agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Binding Sites; Calcium Channel Agonists; Calcium Channels; Computer-Aided Design; Databases, Protein; Dihydropyridines; Drug Design; Ligands; Models, Molecular; Molecular Structure; Protein Conformation; Software; Structure-Activity Relationship | 2009 |
Vasodilation and hypotension of CZ454, an analogue of lacidipine through inhibiting extracellular calcium influx.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Calcium; Calcium Chloride; Calcium Signaling; Dihydropyridines; Hypotension; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Phenylephrine; Potassium; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation; Vasodilator Agents | 2012 |
The inhibitor of connexin Cx36 channels, mefloquine, inhibits voltage-dependent Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Connexins; Dihydropyridines; Gap Junction delta-2 Protein; Glucose; Insulin Secretion; Insulin-Secreting Cells; Ion Channel Gating; Mefloquine; Mice; Nisoldipine; Potassium Chloride; Tolbutamide | 2018 |
Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Binding Sites; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cryoelectron Microscopy; Dihydropyridines; Molecular Dynamics Simulation; Nanostructures; Protein Structure, Tertiary; Stereoisomerism | 2021 |
Lacidipine Attenuates Symptoms of Nicotine Withdrawal in Mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium Channel Blockers; Calcium Channels, L-Type; Catalase; Dihydropyridines; Elevated Plus Maze Test; Female; Glutathione; Hindlimb Suspension; Lipid Peroxidation; Male; Mice; Nicotine; Substance Withdrawal Syndrome; Superoxide Dismutase | 2021 |
Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Asparagine; Calcium; Cryoelectron Microscopy; Dihydropyridines; Isoleucine; Nitrogen Dioxide; Sodium Channels | 2023 |