bay-k-8644 has been researched along with 1,4-dihydropyridine in 124 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (37.10) | 18.7374 |
| 1990's | 55 (44.35) | 18.2507 |
| 2000's | 20 (16.13) | 29.6817 |
| 2010's | 1 (0.81) | 24.3611 |
| 2020's | 2 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Cherksey, B; Llinás, R; Sugimori, M; Usowicz, MM | 1 |
| Bodi, I; Itagaki, K; Klöckner, U; Koch, WJ; Schwartz, A; Slish, DF | 1 |
| Goldmann, S; Stoltefuss, J; Triggle, DJ; Zheng, W | 1 |
| Baumgarten, LB; Toscas, K; Villereal, ML | 1 |
| Ambroz, C; Catt, KJ | 1 |
| Taglietti, V; Toselli, M | 1 |
| Dolphin, AC; Sweeney, MI | 1 |
| Cuccaro, ML; Jacobs, LS; Lorenson, MY | 1 |
| Furukawa, T; Katsuragi, T; Ogawa, S; Shirakabe, K; Soejima, O | 1 |
| Brennan, CH; Littleton, JM | 1 |
| Bacskai, BJ; Friedman, PA | 1 |
| Kunze, DL; Ritchie, AK | 1 |
| Peers, C | 1 |
| Fox, AP; Hirning, LD; Miller, RJ | 1 |
| Florio, T; Grimaldi, M; Landolfi, E; Meucci, O; Schettini, G; Scorziello, A; Ventra, C | 1 |
| Dubyak, GR; Jones, SW; Marks, TN | 1 |
| Fox, AP; Scroggs, RS | 1 |
| Singer, JJ; Vivaudou, MB; Walsh, JV | 1 |
| Regan, LJ | 1 |
| Lory, P; Schultz, D; Schwartz, A; Varadi, G; Varadi, M | 1 |
| Brocklehurst, KW; Ceña, V; Pollard, HB; Rojas, E | 1 |
| Suszkiw, JB; Tomsig, JL | 1 |
| Lin, F; Moran, O; Sciancalepore, M; Zegarra-Moran, O | 1 |
| Drímal, J | 1 |
| Carpenter, CL; Cooper, EC; Greenberg, DA | 1 |
| Schramm, M; Towart, R | 1 |
| Creba, JA; Karobath, M | 1 |
| Glossmann, H; Goll, A; Moosburger, K; Striessnig, J | 1 |
| Callewaert, G; Droogmans, G | 1 |
| Kongsamut, S; Miller, RJ | 1 |
| Bean, BP; Hermsmeyer, K; Puga, A; Sturek, M | 1 |
| Bean, BP; Hess, P; Lansman, JB; Nilius, B; Nowycky, MC; Tsien, RW | 1 |
| Miller, RJ; Murphy, SN; Thayer, SA | 1 |
| Hoffmeister, F; Tettenborn, D | 1 |
| Chernow, B; Ives, N; King, JW; Roth, BL | 1 |
| Gurney, AM; Nerbonne, JM | 1 |
| Brown, AM; Brush, K; Hamilton, SL; Schwartz, A; Yatani, A | 1 |
| Brennan, CH; Charles, S; Hudspith, MJ; Littleton, JM | 1 |
| Challoner-Hue, L; Steele, TH | 1 |
| Hosey, MM; Maan, AC | 1 |
| Atchison, WD; O'Leary, SM | 1 |
| Skattebøl, A; Triggle, DJ | 1 |
| Brisac, AM; Champeroux, P; Gerard, P; Huguet, F; Laurent, S; Lucet, B; Montastruc, JL; Narcisse, G; Schmitt, H | 1 |
| Dunlap, K; Holz, GG; Kream, RM | 1 |
| Oswald, RE; Simasko, SM; Weiland, GA | 1 |
| Bacciottini, L; Carlà, V; Moroni, F; Pellegrini-Giampietro, DE | 1 |
| Knepel, W; Meier, K; Schöfl, C | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Hamilton, SL; Imoto, Y; Yatani, A | 1 |
| Warbanow, W; Will-Shahab, L | 1 |
| Massieu, L; Tapia, R | 1 |
| Dunn, SM | 1 |
| Bergamaschi, S; Cominetti, P; Govoni, S; Parenti, M; Trabucchi, M | 1 |
| Bihoreau, C; Clauser, H; Drouva, SV; Kordon, C; Laplante, E; Rasolonjanahary, R; Rerat, E | 1 |
| Catt, KJ; Hausdorff, WP | 1 |
| Bogónez, E; Martínez-Serrano, A; Satrústegui, J; Vitórica, J | 1 |
| Dunér-Engström, M; Fredholm, BB | 1 |
| Lacerda, AE; Poder, TC; Silberberg, SD | 1 |
| Brown, AM; Skattebøl, A; Triggle, DJ | 1 |
| Anderson, EG; Scroggs, RS | 1 |
| Birnbaumer, L; Brown, AM; Codina, J; Imoto, Y; Mattera, R; Yatani, A | 1 |
| Olsen, R; Powis, G; Seewald, M | 1 |
| Imoto, K; Mikami, A; Mori, Y; Narumiya, S; Niidome, T; Numa, S; Takeshima, H; Tanabe, T | 1 |
| Birnbaumer, L; Brown, AM; Campbell, KP; Horne, W; Kim, HS; Lacerda, AE; Perez-Reyes, E; Rampe, D; Wei, XY | 1 |
| Al-Dahan, MI; Thalmann, RH | 1 |
| Aaronson, PI; Bolton, TB; Lang, RJ; MacKenzie, I | 1 |
| Jones, SW; Marks, TN | 1 |
| Collins, F; Lile, JD | 1 |
| Caffrey, JM; Farach-Carson, MC | 1 |
| Ashcroft, FM; Rorsman, P; Smith, PA | 1 |
| Freedman, SB; Kongsamut, S; Miller, RJ | 1 |
| Gizinski, MJ; Schumaker, KS | 2 |
| de Boland, AR; Vazquez, G | 1 |
| Bagó, A; Deák, F; Hunyady, L; Rohács, T; Spät, A | 1 |
| Hettrick, DA; Pagel, PS; Warltier, DC | 1 |
| Browaeys-Poly, E; Guilbault, P; Ouadid, H; Vilain, JP | 1 |
| Albillos, A; Artalejo, AR; Carbone, E; Gandía, L; García, AG; López, MG | 1 |
| Croxton, TL; Farley, LS; Hirshman, CA; Vannier, C | 1 |
| Berger, AJ; Umemiya, M | 1 |
| Miras-Portugal, MT; Rodriguez-Pascual, F; Torres, M | 1 |
| Beam, KG; Dirksen, RT | 1 |
| Berrow, N; Brickley, K; Campbell, V; Dolphin, AC; Page, K; Wade, R | 1 |
| Albillos, A; Borges, R; Gandía, L; García, AG | 1 |
| Fraser, S; Kenny, BA; Spedding, M | 1 |
| Kimura, T; Satoh, S; Takeuchi, A | 1 |
| Nargeot, J; Neveu, D; Richard, S | 1 |
| MacVicar, BA; Pittman, QJ; Williams, PJ | 1 |
| Johnson, MS; MacEwan, DJ; Mitchell, R; Thomson, FJ | 1 |
| Ayata, C; Dalkara, T; Demirci, M; Erdemli, G; Onur, R | 1 |
| Bindokas, VP; Ishida, AT | 1 |
| Kamishima, T; McCarron, JG | 1 |
| Brown, DA; Filippov, AK | 1 |
| Biancardi, E; Carbone, E; Clementi, F; Davalli, AM; Pollo, A; Pontiroli, AE; Pozza, G; Sher, E; Socci, C | 1 |
| Gan, J; Iuvone, PM | 1 |
| Hofmann, F; Ito, H; Klugbauer, N | 1 |
| Gollasch, M; Haase, H; Haller, H; Lindschau, C; Luft, FC; Morano, I; Ried, C | 1 |
| Ouadid-Ahidouch, H | 1 |
| Kanaya, N; Kawana, S; Kimura, H; Matsumoto, M; Miyamoto, A; Namiki, A; Ohshika, H; Tsuchida, H | 1 |
| de la Villa, P; Kaneko, A; Vaquero, CF | 1 |
| Athmann, C; Kang, T; Sachs, G; Walsh, JH; Zeng, N | 1 |
| Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
| Bito, H; Deisseroth, K; Mermelstein, PG; Tsien, RW | 1 |
| Thoreson, WB | 1 |
| Hanna, ST; Tang, G; Wang, R; Wu, L; Wu, Y | 1 |
| Kang, TM; Kim, CH; Kim, KW; Kim, YI; Park, MK; Rhee, JC; Rhee, PL; So, I; Uhm, DY | 1 |
| Bell, DC; Berrow, NS; Brust, PF; Butcher, AJ; Dolphin, AC; Nesterova, A; Nürnberg, B; Page, KM; Seabrook, GR; Stauderman, KA | 1 |
| Kan, E; Kelly, JE; Lokuta, AJ; Nishio, M; Sagawa, K; Sagawa, T; Tsai, J; Wasserstrom, JA | 1 |
| Gerzanich, V; Simard, JM; West, GA; Zhang, F | 1 |
| Carroll, EM; Collins, PL; Gianopoulos, JG | 1 |
| Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L | 1 |
| Lipscombe, D; Xu, W | 1 |
| Brown, G; Losonczy, G; Schoenl, M; Venuto, R | 1 |
| Birkenbeil, H; Dedos, SG | 1 |
| Armstrong, DL; Birnbaumer, L; Darden, T; Erxleben, C; Gomez-Alegria, C; Mori, Y | 1 |
| Hino, N; Masumiya, H; Ochi, R; Tsujikawa, H | 1 |
| Grabner, M; Heinzle, T; Hoda, JC; Koschak, A; Reimer, D; Striessnig, J; Walter, D | 1 |
| Cota, G; Espinosa, JL; López-Domínguez, AM; López-Santiago, LF; Navarrete, A; Vega, AV | 1 |
| Darcy, DP; Isaacson, JS; Murphy, GJ | 1 |
| Aishima, M; Ito, Y; Teramoto, N; Tomoda, T; Zhu, HL | 1 |
| Dupere, JR; Payne, CE; Tringham, EW; Usowicz, MM | 1 |
| Davood, A; Iman, M; Nematollahi, AR; Shafiee, A | 1 |
| Rustenbeck, I; Seemann, N; Welling, A | 1 |
| Gao, S; Yan, N | 1 |
| Tikhonov, DB; Zhorov, BS | 1 |
3 review(s) available for bay-k-8644 and 1,4-dihydropyridine
| Article | Year |
|---|---|
Modulation of calcium channel function by drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Electric Conductivity; Heart Rate; Homeostasis; Humans; Ion Channels; Membrane Potentials; Nifedipine; Pyridines; Receptors, Cell Surface; Structure-Activity Relationship | 1985 |
Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium; Dihydropyridines; In Vitro Techniques; Ion Channels; Isoproterenol; Kinetics; Models, Biological; Nifedipine; Phosphorylation; Pyridines; Receptors, Adrenergic, beta | 1986 |
Direct G-protein regulation of Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cattle; Dihydropyridines; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Humans; Isoproterenol; Thionucleotides | 1989 |
121 other study(ies) available for bay-k-8644 and 1,4-dihydropyridine
| Article | Year |
|---|---|
P-type calcium channels in the somata and dendrites of adult cerebellar Purkinje cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Dendrites; Dihydropyridines; Electric Stimulation; Electrophysiology; Evoked Potentials; Female; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Purkinje Cells | 1992 |
Native-type DHP-sensitive calcium channel currents are produced by cloned rat aortic smooth muscle and cardiac alpha 1 subunits expressed in Xenopus laevis oocytes and are regulated by alpha 2- and beta-subunits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Calcium Channels; Cloning, Molecular; Dihydropyridines; Electric Conductivity; Female; Gene Expression Regulation; Muscle, Smooth, Vascular; Myocardium; Oocytes; Rabbits; Rats; Xenopus laevis | 1992 |
Pharmacologic and radioligand binding studies of 1,4-dihydropyridines in rat cardiac and vascular preparations: stereoselectivity and voltage dependence of antagonist and activator interactions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Binding, Competitive; Calcium Channel Blockers; Dihydropyridines; Drug Antagonism; Heart; In Vitro Techniques; Isradipine; Male; Muscle Contraction; Nifedipine; Radioligand Assay; Rats | 1992 |
Dihydropyridine-sensitive L-type Ca2+ channels in human foreskin fibroblast cells. Characterization of activation with the growth factor Lys-bradykinin.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cells, Cultured; Dihydropyridines; Fibroblasts; Fura-2; Humans; Ion Channel Gating; Kallidin; Nitrendipine | 1992 |
Angiotensin II receptor-mediated calcium influx in bovine adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Calcium Channels; Cattle; Cells, Cultured; Dihydropyridines; GTP-Binding Proteins; Imidazoles; Lanthanum; Losartan; Pertussis Toxin; Receptors, Angiotensin; Tetrazoles; Virulence Factors, Bordetella; Zona Glomerulosa | 1992 |
Kinetic and pharmacological properties of high- and low-threshold calcium channels in primary cultures of rat hippocampal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Electrophysiology; Hippocampus; Kinetics; Neurons; Nickel; omega-Conotoxin GVIA; Peptides, Cyclic; Rats | 1992 |
1,4-Dihydropyridines modulate GTP hydrolysis by Go in neuronal membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Calcium Channels; Cell Membrane; Cerebral Cortex; Dihydropyridines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immune Sera; Male; Neurons; Rats; Rats, Inbred Strains | 1992 |
Calcium release from pituitary secretory granules: modulation by thiols, disulfides, and dihydropyridine calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cattle; Cysteine; Cystine; Cytoplasmic Granules; Dihydropyridines; Disulfides; Dithiothreitol; Glutathione; Hydrogen-Ion Concentration; Mercaptoethanol; Nifedipine; Nimodipine; Pituitary Gland; Potassium Chloride; Sulfhydryl Compounds | 1990 |
Involvement of dihydropyridine-sensitive Ca2+ channels in adenosine-evoked inhibition of acetylcholine release from guinea pig ileal preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Acetylcholine; Adenosine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Calcium Channels; Chromatography, High Pressure Liquid; Dihydropyridines; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle, Smooth; Nifedipine; Physostigmine; Tetrodotoxin; Theophylline | 1990 |
Second messengers involved in genetic regulation of the number of calcium channels in bovine adrenal chromaffin cells in culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Animals; Calcium Channels; Cattle; Cells, Cultured; Chromaffin System; Dihydropyridines; Gene Expression; Inositol Phosphates; Kinetics; Pertussis Toxin; Phorbol Esters; Second Messenger Systems; Up-Regulation; Virulence Factors, Bordetella | 1990 |
Activation of latent Ca2+ channels in renal epithelial cells by parathyroid hormone.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Absorption; Animals; Biological Transport; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Dihydropyridines; Epithelium; Exocytosis; Kidney Tubules, Distal; Kinetics; Mice; Microtubules; Nifedipine; Parathyroid Hormone; Peptide Fragments | 1990 |
Multiple conductance levels of the dihydropyridine-sensitive calcium channel in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channels; Cell Line; Dihydropyridines; Electric Conductivity; Humans; Nimodipine; Pituitary Gland, Anterior | 1990 |
Hypoxic suppression of K+ currents in type I carotid body cells: selective effect on the Ca2(+)-activated K+ current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Calcium Channel Blockers; Carotid Body; Dihydropyridines; Electrophysiology; Hypoxia; Nifedipine; Potassium; Rats | 1990 |
Inhibition of calcium currents in cultured myenteric neurons by neuropeptide Y: evidence for direct receptor/channel coupling.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Cells, Cultured; Dihydropyridines; Fura-2; Membrane Potentials; Myenteric Plexus; Neurons; Neuropeptide Y; Nitrendipine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Neuropeptide Y; Receptors, Neurotransmitter; Virulence Factors, Bordetella | 1990 |
Dihydropyridine modulation of voltage-activated calcium channels in PC12 cells: effect of pertussis toxin pretreatment.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophysiology; Nicardipine; Pertussis Toxin; Pheochromocytoma; Potassium; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Calcium currents in the A7r5 smooth muscle-derived cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Biological Transport; Calcium; Calcium Channels; Cell Line; Colforsin; Cytosol; Dihydropyridines; Electric Conductivity; Fluorescence; Isoproterenol; Ligands; Muscle, Smooth, Vascular; Nifedipine; Potassium | 1990 |
Distribution of dihydropyridine and omega-conotoxin-sensitive calcium currents in acutely isolated rat and frog sensory neuron somata: diameter-dependent L channel expression in frog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channels; Dihydropyridines; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Kinetics; Membrane Potentials; Mollusk Venoms; Neurons, Afferent; Nimodipine; omega-Conotoxin GVIA; Peptides, Cyclic; Ranidae; Rats; Species Specificity | 1991 |
Multiple types of Ca2+ channels in visceral smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Bufo marinus; Calcium Channels; Dihydropyridines; Electric Conductivity; Gastric Mucosa; In Vitro Techniques; Kinetics; Muscle, Smooth; Stomach | 1991 |
Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Barium; Calcium Channels; Cell Separation; Dihydropyridines; Electric Conductivity; Electrophysiology; Nickel; Nimodipine; Nitrendipine; Purkinje Cells; Rats | 1991 |
Acceleration of activation and inactivation by the beta subunit of the skeletal muscle calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Binding Sites; Calcium Channels; Cell Line; Cell Membrane; Dihydropyridines; DNA; Electric Conductivity; Gene Expression; Ion Channel Gating; Isradipine; Kinetics; L Cells; Macromolecular Substances; Muscles; Oxadiazoles; Rabbits; Receptors, Nicotinic; Transfection | 1991 |
Pertussis toxin stimulation of catecholamine release from adrenal medullary chromaffin cells: mechanism may be by direct activation of L-type and G-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Dihydropyridines; Electric Conductivity; Membrane Potentials; Nifedipine; Pertussis Toxin; Verapamil; Virulence Factors, Bordetella | 1991 |
Permeation of Pb2+ through calcium channels: fura-2 measurements of voltage- and dihydropyridine-sensitive Pb2+ entry in isolated bovine chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Calcium Channels; Cattle; Cell Membrane Permeability; Cell Separation; Dihydropyridines; Fura-2; Lead; Membrane Potentials; Nifedipine | 1991 |
Voltage dependent calcium channels in cerebellar granule cell primary cultures.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium Channels; Cells, Cultured; Cerebellum; Dihydropyridines; Electrophysiology | 1991 |
The beta-adrenergic receptor-regulated 1,4-dihydropyridine calcium channel receptor sites in coronary artery smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cell Membrane; Cyclic AMP; Dihydropyridines; Dogs; Guanosine Triphosphate; Isoproterenol; Isradipine; Male; Microsomes; Muscle, Smooth, Vascular; Receptors, Adrenergic, beta | 1991 |
Stimulation of calcium uptake in PC12 cells by the dihydropyridine agonist BAY K 8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Gland Neoplasms; Animals; Calcium; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Nifedipine; Nitrendipine; Pheochromocytoma; Pyridines; Rats | 1985 |
The effect of dihydropyridine calcium agonists and antagonists on neuronal voltage sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Brain Chemistry; Calcium; Calcium Channel Blockers; Cell Line; Dihydropyridines; Electric Stimulation; Glioma; In Vitro Techniques; Ion Channels; Neuroblastoma; Neurons; Nifedipine; Potassium; Pyridines; Rats; Synaptosomes; Verapamil | 1986 |
Purified calcium channels have three allosterically coupled drug receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1986 |
Ca2+-channel current and its modification by the dihydropyridine agonist BAY k 8644 in isolated smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Barium; Barium Compounds; Cell Membrane; Cesium; Chlorides; Dihydropyridines; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscle, Smooth; Nifedipine; Pyridines | 1986 |
Nerve growth factor modulates the drug sensitivity of neurotransmitter release from PC-12 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bucladesine; Calcium; Cell Differentiation; Dihydropyridines; Nerve Growth Factors; Nifedipine; Nitrendipine; Norepinephrine; Pheochromocytoma; Potassium; Pyridines; Rats; Secretory Rate | 1986 |
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Pyridines; Rats | 1986 |
Widespread distribution of dihydropyridine-sensitive calcium channels in the central nervous system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Cells, Cultured; Cytosol; Dihydropyridines; Hippocampus; Ion Channels; Mice; Mice, Inbred C57BL; Neurons; Organ Specificity; Pyridines; Rats; Rats, Inbred Strains | 1986 |
Calcium agonists and antagonists of the dihydropyridine type: antinociceptive effects, interference with opiate-mu-receptor agonists and neuropharmacological actions in rodents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Analgesics; Animals; Anticonvulsants; Behavior, Animal; Calcium Channel Blockers; Dihydropyridines; Female; Motor Activity; Pain Measurement; Postural Balance; Pyridines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu | 1986 |
BAY k 8644, a calcium channel agonist, reverses hypotension in endotoxin-shocked rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Dihydropyridines; Dose-Response Relationship, Drug; Male; Microsomes; Myocardium; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Shock, Septic | 1986 |
Blockade of Ca2+ and K+ currents in bag cell neurons of Aplysia californica by dihydropyridine Ca2+ antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aplysia; Calcium; Calcium Channel Blockers; Dihydropyridines; Ion Channels; Kinetics; Mathematics; Neurons; Nifedipine; Nisoldipine; Potassium; Pyridines | 1987 |
A comparison between the binding and electrophysiological effects of dihydropyridines on cardiac membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Heart; Ion Channels; Isradipine; Kinetics; Membrane Potentials; Membranes; Myocardium; Nicotinic Acids; Nimodipine; Nitrendipine; Oxadiazoles; Pyridines; Stereoisomerism; Structure-Activity Relationship | 1987 |
Dihydropyridine-sensitive Ca2+ channels and inositol phospholipid metabolism in ethanol physical dependence.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alcoholism; Animals; Cerebral Cortex; Dihydropyridines; Hydroxydopamines; In Vitro Techniques; Inositol Phosphates; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Nitrendipine; Oxidopamine; Pyridines; Rats; Rats, Inbred Strains; Sugar Phosphates; Vas Deferens | 1987 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
Analysis of the properties of binding of calcium-channel activators and inhibitors to dihydropyridine receptors in chick heart membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Cations, Divalent; Chickens; Dihydropyridines; Ion Channels; Kinetics; Ligands; Membranes; Myocardium; Pyridines; Receptors, Cell Surface; Temperature | 1987 |
BAY K 8644 increases release of acetylcholine at the murine neuromuscular junction.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Dihydropyridines; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neuromuscular Junction; Nimodipine; Rats; Rats, Inbred Strains | 1987 |
Regional distribution of calcium channel ligand (1,4-dihydropyridine) binding sites and 45Ca2+ uptake processes in rat brain.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium; Calcium Channels; Caudate Nucleus; Cell Membrane; Cerebellum; Cerebral Cortex; Dihydropyridines; Hippocampus; Male; Nimodipine; Olfactory Bulb; Potassium; Rats; Receptors, Nicotinic; Synaptosomes; Tissue Distribution | 1987 |
Central interactions between dihydropyridines and cholinergic systems in the control of blood pressure in rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Atropine Derivatives; Blood Pressure; Cerebral Ventricles; Dihydropyridines; Hemicholinium 3; Hexamethonium; Hexamethonium Compounds; Hippocampus; In Vitro Techniques; Male; Nicardipine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Reference Values; Species Specificity | 1987 |
Characterization of the electrically evoked release of substance P from dorsal root ganglion neurons: methods and dihydropyridine sensitivity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Chick Embryo; Dihydropyridines; Electric Stimulation; Ganglia, Spinal; Nifedipine; Substance P | 1988 |
Pharmacological characterization of two calcium currents in GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Dihydropyridines; Electrophysiology; Ion Channels; Nitrendipine; Osmolar Concentration; Pituitary Gland; Rats | 1988 |
Morphine withdrawal in cortical slices: suppression by Ca2+-channel inhibitors of abstinence-induced [3H]-noradrenaline release.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Cerebral Cortex; Dihydropyridines; Disease Models, Animal; In Vitro Techniques; Ion Channels; Morphine; Naloxone; Nimodipine; Norepinephrine; Rats; Substance Withdrawal Syndrome; Tritium | 1988 |
Potassium depolarization elevates cytosolic free calcium concentration in rat anterior pituitary cells through 1,4-dihydropyridine-sensitive, omega-conotoxin-insensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzofurans; Calcium; Calcium Channel Blockers; Cytosol; Dihydropyridines; Fluorescent Dyes; Fura-2; Ion Channels; Magnesium; Male; Membrane Potentials; Mollusk Venoms; omega-Conotoxins; Pituitary Gland, Anterior; Potassium; Rats; Rats, Inbred Strains | 1988 |
The stimulatory G protein of adenylyl cyclase, Gs, also stimulates dihydropyridine-sensitive Ca2+ channels. Evidence for direct regulation independent of phosphorylation by cAMP-dependent protein kinase or stimulation by a dihydropyridine agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Calcium; Cell Membrane; Cholera Toxin; Cyclic AMP; Dihydropyridines; Electric Conductivity; Erythrocytes; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Ion Channels; Lipid Bilayers; Muscles; Myocardium; Phosphorylation; Protein Kinases; Thionucleotides | 1988 |
Altered effect of BAY K 8644 after exposure of the rat aorta to IBMX or Db cAMP.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Bucladesine; Cyclic AMP; Dihydropyridines; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred Strains; Theophylline | 1988 |
Relationship of dihydropyridine binding sites with calcium-dependent neurotransmitter release in synaptosomes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 4-Aminopyridine; Aminopyridines; Animals; Brain; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; gamma-Aminobutyric Acid; Ion Channels; Isradipine; Lanthanum; Male; Mice; Neurotransmitter Agents; Nifedipine; Nitrendipine; Oxadiazoles; Potassium; Receptors, Nicotinic; Ruthenium Red; Synaptosomes | 1988 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Direct coupling of a G-protein to dihydropyridine binding sites.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channels; Cerebral Cortex; Dihydropyridines; GTP-Binding Proteins; Guanosine Triphosphate; Male; Pertussis Toxin; Protein Binding; Rats; Rats, Inbred Strains; Synaptic Membranes; Virulence Factors, Bordetella | 1988 |
Dihydropyridine-sensitive calcium channel activity related to prolactin, growth hormone, and luteinizing hormone release from anterior pituitary cells in culture: interactions with somatostatin, dopamine, and estrogens.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Calcium Radioisotopes; Cells, Cultured; Dihydropyridines; Dopamine; Estradiol; Female; Growth Hormone; Luteinizing Hormone; Male; Nitrendipine; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Potassium; Prolactin; Rats; Rats, Inbred Strains; Sex Characteristics; Somatostatin | 1988 |
Activation of dihydropyridine-sensitive calcium channels and biphasic cytosolic calcium responses by angiotensin II in rat adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium; Calcium Channels; Cattle; Cytosol; Dihydropyridines; Ethers; Ionomycin; Kinetics; Male; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Species Specificity; Spectrometry, Fluorescence; Zona Glomerulosa | 1988 |
Reduction of K+-stimulated 45Ca2+ influx in synaptosomes with age involves inactivating and noninactivating calcium channels and is correlated with temporal modifications in protein dephosphorylation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aging; Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Dihydropyridines; Kinetics; Male; Molecular Weight; Nifedipine; Phosphoproteins; Phosphorylation; Potassium; Rats; Rats, Inbred Strains; Synaptosomes | 1989 |
Evidence that prejunctional adenosine receptors regulating acetylcholine release from rat hippocampal slices are linked to an N-ethylmaleimide-sensitive G-protein, but not to adenylate cyclase or dihydropyridine-sensitive Ca2+-channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylyl Cyclases; Animals; Calcium Channel Blockers; Carrier Proteins; Cyclic AMP; Dihydropyridines; Electric Stimulation; Ethylmaleimide; GTP-Binding Proteins; Hippocampus; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Neurotransmitter; Receptors, Purinergic | 1988 |
Endothelin increases single-channel calcium currents in coronary arterial smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channels; Coronary Vessels; Dihydropyridines; Electric Conductivity; Endothelins; Endothelium, Vascular; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Peptides; Second Messenger Systems; Swine | 1989 |
Homologous regulation of voltage-dependent calcium channels by 1,4-dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Cell Line; Dihydropyridines; Kinetics; Membrane Potentials; Pheochromocytoma; Radioligand Assay; Rats; Receptors, Nicotinic | 1989 |
Serotonin modulates calcium-dependent plateau of action potentials recorded from bull frog A-type sensory neurons which is omega-conotoxin GVIA-sensitive, but dihydropyridine-insensitive.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Dihydropyridines; Ganglia, Spinal; In Vitro Techniques; Mollusk Venoms; Neurons, Afferent; Nifedipine; omega-Conotoxin GVIA; Rana catesbeiana; Serotonin; Tetraethylammonium Compounds | 1989 |
Contribution of external and internal Ca2+ to changes in intracellular free Ca2+ produced by mitogens in Swiss 3T3 fibroblasts: the role of dihydropyridine sensitive Ca2+ channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cell Line; Cytosol; Dihydropyridines; Extracellular Space; Fibroblasts; Mice; Mitogens; Nifedipine; Platelet-Derived Growth Factor | 1989 |
Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Calcium Channels; Dihydropyridines; DNA; Electric Conductivity; Female; Gene Expression Regulation; Molecular Sequence Data; Molecular Weight; Muscles; Myocardium; Oocytes; Rabbits; Receptors, Nicotinic; RNA, Messenger; Sequence Homology, Nucleic Acid; Xenopus | 1989 |
Induction of calcium currents by the expression of the alpha 1-subunit of the dihydropyridine receptor from skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Calcium Channels; Cloning, Molecular; Dihydropyridines; DNA; Electric Conductivity; Gene Expression Regulation; Immunoblotting; L Cells; Macromolecular Substances; Mice; Molecular Weight; Muscles; Receptors, Nicotinic; Transfection; Transformation, Genetic | 1989 |
Effects of dihydropyridine calcium channel ligands on rat brain gamma-aminobutyric acidB receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Binding, Competitive; Calcium Channels; Dihydropyridines; Male; Nifedipine; Rats; Receptors, GABA-A | 1989 |
Calcium currents in single isolated smooth muscle cells from the rabbit ear artery in normal-calcium and high-barium solutions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Dihydropyridines; Ear; Electric Conductivity; Membrane Potentials; Muscle, Smooth, Vascular; Nifedipine; Rabbits | 1988 |
Calcium currents in bullfrog sympathetic neurons. I. Activation kinetics and pharmacology.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Cadmium; Calcium Channel Agonists; Calcium Channels; Dihydropyridines; Ganglia, Sympathetic; Kinetics; Membrane Potentials; Neurons; Nifedipine; Rana catesbeiana; Saxitoxin; Second Messenger Systems | 1989 |
The role of dihydropyridine-sensitive voltage-gated calcium channels in potassium-mediated neuronal survival.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Dihydropyridines; Membrane Potentials; Neurons; Potassium | 1989 |
Vitamin D3 metabolites modulate dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells.
Topics: 24,25-Dihydroxyvitamin D 3; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcifediol; Calcitriol; Calcium; Calcium Channels; Cell Line; Dihydropyridines; Kinetics; Membrane Potentials; Osteosarcoma; Rats; Tumor Cells, Cultured | 1989 |
Modulation of dihydropyridine-sensitive Ca2+ channels by glucose metabolism in mouse pancreatic beta-cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Dihydropyridines; Electric Conductivity; Glucose; In Vitro Techniques; Islets of Langerhans; Membrane Potentials; Mice | 1989 |
Dihydropyridine sensitive calcium channels in a smooth muscle cell line.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium; Cell Line; Cobalt; Dihydropyridines; Ion Channels; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Potassium; Pyridines; Rats | 1985 |
Cytokinin stimulates dihydropyridine-sensitive calcium uptake in moss protoplasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Biological Transport; Calcium; Calcium Channels; Cell Differentiation; Cells, Cultured; Dihydropyridines; In Vitro Techniques; Ion Channel Gating; Plant Cells; Plant Growth Regulators; Plant Physiological Phenomena; Potassium | 1993 |
"Stimulation of dihydropyridine-sensitive Ca2+ influx in cultured myoblasts by 1,25(OH)2-vitamin D3".
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcitriol; Calcium Channels; Cells, Cultured; Chick Embryo; Dihydropyridines; Egtazic Acid; Muscles; Nifedipine; Rats; Rats, Wistar | 1993 |
Dihydropyridine-sensitive initial component of the ANG II-induced Ca2+ response in rat adrenal glomerulosa cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Animals; Calcium; Calcium Channels, L-Type; Dihydropyridines; Female; Manganese; Membrane Potentials; Muscle Proteins; Nifedipine; Potassium; Rats; Rats, Wistar; Zona Glomerulosa | 1994 |
Left ventricular mechanical consequences of dihydropyridine calcium channel modulation in conscious and anesthetized chronically instrumented dogs.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Anesthetics; Animals; Autonomic Nerve Block; Autonomic Nervous System; Calcium Channels; Consciousness; Diastole; Dihydropyridines; Dogs; Drug Interactions; Halothane; Hemodynamics; Isoflurane; Myocardial Contraction; Nifedipine; Systole; Ventricular Function, Left | 1994 |
Endogenous DHP-sensitive Ca(2+) channels in Pleurodeles oocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Calcium; Calcium Channels; Dihydropyridines; Membrane Potentials; Mollusk Venoms; Nifedipine; omega-Conotoxin GVIA; Oocytes; Peptides; Pleurodeles | 1994 |
Calcium channel subtypes in cat chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Barium; Calcium Channels; Cats; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Female; Ion Channel Gating; Male; Membrane Potentials; Nisoldipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides | 1994 |
Inhibition of dihydropyridine-sensitive calcium entry in hypoxic relaxation of airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bronchi; Calcium; Calcium Channel Blockers; Carbachol; Dihydropyridines; Female; Hypoxia; Male; Muscle Relaxation; Muscle, Smooth; Nifedipine; Potassium Chloride; Swine | 1995 |
Single-channel properties of four calcium channel types in rat motoneurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channels; Dihydropyridines; Hypoglossal Nerve; Motor Neurons; Nerve Tissue Proteins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Spider Venoms | 1995 |
Modulation of the dihydropyridine-insensitive Ca2+ influx by 8-bromo-guanosine-3':5'-monophosphate, cyclic (8-Br-cGMP) in bovine adrenal chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Bucladesine; Calcium; Calcium Channels; Cattle; Cells, Cultured; Cyclic GMP; Dihydropyridines; Neomycin; Nerve Tissue Proteins; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Potassium Chloride; Second Messenger Systems; Spider Venoms | 1994 |
Single calcium channel behavior in native skeletal muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium Compounds; Cadmium; Cadmium Chloride; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Chlorides; Dihydropyridines; Electrophysiology; Isradipine; Lanthanum; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Patch-Clamp Techniques | 1995 |
Voltage-dependent calcium channel beta-subunits in combination with alpha 1 subunits, have a GTPase activating effect to promote the hydrolysis of GTP by G alpha o in rat frontal cortex.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Animals; Binding Sites; Calcium Channels; Cell Membrane; Dihydropyridines; Enzyme Activation; Frontal Lobe; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Peptide Fragments; Rats | 1995 |
Multiple calcium channel subtypes in isolated rat chromaffin cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Medulla; Animals; Barium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cells, Cultured; Dihydropyridines; Female; Ion Channel Gating; Ion Transport; Male; Membrane Potentials; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Species Specificity; Spider Venoms | 1995 |
Identification of a novel calcium antagonist binding site in rat brain by SR 33557.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding Sites; Calcium Channel Blockers; Cations, Divalent; Cations, Monovalent; Cecum; Cerebral Cortex; Dihydropyridines; Female; Guinea Pigs; Indolizines; Male; Muscle Contraction; Muscle, Smooth; Phenethylamines; Rats; Rats, Sprague-Dawley | 1993 |
Effects of nifedipine and Bay-K-8644 on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenal Glands; Anesthesia; Animals; Calcium Channels; Dihydropyridines; Dogs; Electric Stimulation; Epinephrine; Female; Male; Nifedipine; Norepinephrine; Sensitivity and Specificity; Splanchnic Nerves | 1993 |
Two high-voltage-activated, dihydropyridine-sensitive Ca2+ channel currents with distinct electrophysiological and pharmacological properties in cultured rat aortic myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta; Barium; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Dihydropyridines; Electric Conductivity; Electrophysiology; Male; Muscle, Smooth, Vascular; Nicardipine; Rats; Rats, Wistar | 1993 |
Blockade by funnel web toxin of a calcium current in the intermediate pituitary of the rat.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Cadmium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Ion Channel Gating; Male; Mollusk Venoms; Nickel; Peptides; Pituitary Gland; Polyamines; Rats; Rats, Sprague-Dawley; Spider Venoms | 1993 |
The involvement of dihydropyridine-sensitive calcium channels in phorbol ester-induced luteinizing hormone and growth hormone release.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Animals; Calcium; Calcium Channels; Dihydropyridines; Female; Growth Hormone; Ion Channel Gating; Isoquinolines; Luteinizing Hormone; Phorbol 12,13-Dibutyrate; Piperazines; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Staurosporine | 1993 |
Effects of cerebral ischemia on N-methyl-D-aspartate and dihydropyridine-sensitive calcium currents. An electrophysiological study in the rat hippocampus in situ.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electric Impedance; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Agonists; Hippocampus; Ion Channels; Iontophoresis; Ischemic Attack, Transient; Male; Membrane Potentials; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Reperfusion | 1996 |
Conotoxin-sensitive and conotoxin-resistant Ca2+ currents in fish retinal ganglion cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Agatoxins; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Dihydropyridines; Goldfish; Membrane Potentials; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Retinal Ganglion Cells; Spider Venoms | 1996 |
G proteins regulate dihydropyridine binding to moss plasma membranes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Binding Sites; Bryopsida; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; GTP-Binding Proteins; Guanine Nucleotides; Nifedipine | 1996 |
Depolarization-evoked increases in cytosolic calcium concentration in isolated smooth muscle cells of rat portal vein.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Cytophotometry; Cytosol; Dihydropyridines; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nimodipine; Patch-Clamp Techniques; Portal Vein; Rats; Rats, Sprague-Dawley; Ryanodine; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Activation of nucleotide receptors inhibits high-threshold calcium currents in NG108-15 neuronal hybrid cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Hybrid Cells; Mice; Mollusk Venoms; Neuroblastoma; Neurons; Nifedipine; omega-Conotoxin GVIA; Peptides; Pertussis Toxin; Rats; Receptors, Cell Surface; Virulence Factors, Bordetella | 1996 |
Dihydropyridine-sensitive and -insensitive voltage-operated calcium channels participate in the control of glucose-induced insulin release from human pancreatic beta cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adult; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mollusk Venoms; Nitrendipine; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides | 1996 |
Depolarization and activation of dihydropyridine-sensitive Ca2+ channels stimulate inositol phosphate accumulation in photoreceptor-enriched chick retinal cell cultures.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Chick Embryo; Dihydropyridines; Electric Stimulation; Estrenes; Inositol Phosphates; Membrane Potentials; Nifedipine; Pertussis Toxin; Phosphatidylinositol 4,5-Diphosphate; Phosphodiesterase Inhibitors; Photoreceptor Cells; Potassium; Pyrrolidinones; Type C Phospholipases; Virulence Factors, Bordetella | 1997 |
Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Calcium Channel Blockers; Calcium Channels; Cell Line; Dihydropyridines; Humans; Isradipine; Molecular Sequence Data; Mutagenesis, Site-Directed | 1997 |
L-type calcium channel expression depends on the differentiated state of vascular smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Actins; Animals; Aorta; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Differentiation; Cell Line; Culture Media; Dihydropyridines; Kinetics; Membrane Potentials; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nimodipine; Patch-Clamp Techniques; Rats; Tretinoin | 1998 |
Voltage-gated calcium channels in Pleurodeles oocytes: classification, modulation and functional roles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Breeding; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP-Dependent Protein Kinases; Dihydropyridines; Electric Stimulation; Ion Channel Gating; Ion Transport; Meiosis; Membrane Potentials; Nickel; Nifedipine; omega-Conotoxin GVIA; Oocytes; Peptides; Phosphorylation; Pleurodeles; Progesterone; Protein Processing, Post-Translational; Seasons; Second Messenger Systems | 1998 |
Ca2+ channel modulation alters halothane-induced depression of ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Wistar; Sarcolemma; Verapamil | 1998 |
Two types of calcium currents of the mouse bipolar cells recorded in the retinal slice preparation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cobalt; Dihydropyridines; Membrane Potentials; Mice; Mice, Inbred Strains; omega-Conotoxin GVIA; Organ Culture Techniques; Patch-Clamp Techniques; Peptides; Retina; Tetraethylammonium | 1998 |
Role of neuropeptide-sensitive L-type Ca(2+) channels in histamine release in gastric enterochromaffin-like cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenylate Cyclase Toxin; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; DNA Primers; Enterochromaffin-like Cells; Galanin; Gastric Acid; Gastric Mucosa; Gastrins; Gene Expression; GTP-Binding Proteins; Histamine; Histamine Release; Membrane Potentials; Neuropeptides; Neurotransmitter Agents; omega-Conotoxin GVIA; Peptide YY; Pertussis Toxin; Pituitary Adenylate Cyclase-Activating Polypeptide; Potassium; Rabbits; Rats; Receptors, Histamine H2; Somatostatin; Stomach; Tetraethylammonium; Virulence Factors, Bordetella | 1999 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials.
Topics: 2-Amino-5-phosphonovalerate; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Calmodulin; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression; Hippocampus; Ion Channel Gating; N-Methylaspartate; Phosphorylation; Pyramidal Cells; Rats | 2000 |
Dihydropyridine-sensitive calcium currents in bipolar cells of salamander retina are inhibited by reductions in extracellular chloride.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Ambystoma; Animals; Barium; Calcium Channels, L-Type; Chlorides; Dihydropyridines; Gluconates; In Vitro Techniques; Larva; Membrane Potentials; Nisoldipine; Nystatin; Patch-Clamp Techniques; Photoreceptor Cells, Vertebrate; Retina | 2000 |
Altered L-type Ca(2+) channel currents in vascular smooth muscle cells from experimental diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arteries; Bucladesine; Calcium Channels, L-Type; Cells, Cultured; Cyclic AMP; Diabetes Mellitus, Experimental; Dihydropyridines; Electric Conductivity; Glucose; Male; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Tail | 2000 |
Hypotonic swelling increases L-type calcium current in smooth muscle cells of the human stomach.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Size; Cells, Cultured; Dihydropyridines; Electric Conductivity; Fluorometry; Gastric Mucosa; Humans; Hypotonic Solutions; Muscle, Smooth, Vascular; Osmotic Pressure; Patch-Clamp Techniques; Stomach | 2000 |
Biophysical properties, pharmacology, and modulation of human, neuronal L-type (alpha(1D), Ca(V)1.3) voltage-dependent calcium currents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Electric Conductivity; Glutathione Transferase; GTP-Binding Proteins; Humans; Neurons; Protein Isoforms; Recombinant Fusion Proteins | 2001 |
Activation of purified cardiac ryanodine receptors by dihydropyridine agonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Dogs; Membrane Potentials; Myocardium; Nicotinic Acids; Nifedipine; Oxadiazoles; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Stereoisomerism | 2001 |
Chronic nicotine alters NO signaling of Ca(2+) channels in cerebral arterioles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arterioles; Barium; Calcium; Calcium Channels; Calcium Channels, L-Type; Cerebral Arteries; Cerebrovascular Circulation; Cyclic GMP; Dihydropyridines; Electric Stimulation; Female; Membrane Potentials; Muscle, Smooth, Vascular; Nicotine; Nifedipine; Nitric Oxide; Nitroprusside; Potassium Channels; Rats; Rats, Inbred WKY; Signal Transduction; Time Factors; Tyrphostins | 2001 |
Abnormality of calcium channel inhibitor released from fetal membranes in preterm labor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Extraembryonic Membranes; Female; Guinea Pigs; Humans; Isradipine; Obstetric Labor, Premature; Organ Specificity; Placenta; Pregnancy; Random Allocation; Rats; Rats, Wistar; Uterine Contraction | 2001 |
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil | 2001 |
Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alternative Splicing; Animals; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Kidney; Membrane Potentials; Molecular Sequence Data; Nimodipine; Oocytes; Patch-Clamp Techniques; Protein Subunits; Rats; Signal Transduction; Transfection; Xenopus | 2001 |
Enhanced vascular effects of the Ca(2+) channel agonist Bay K 8644 in pregnant rabbits.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; 6-Ketoprostaglandin F1 alpha; Anesthesia; Animals; Aorta; Blood Pressure; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiac Output; Consciousness; Dihydropyridines; Female; Heart Rate; Muscle, Smooth, Vascular; Nifedipine; Pregnancy; Pregnancy, Animal; Rabbits; Thromboxane B2; Tritium | 2002 |
Inhibition of cAMP signalling cascade-mediated Ca2+ influx by a prothoracicostatic peptide (Mas-MIP I) via dihydropyridine-sensitive Ca2+ channels in the prothoracic glands of the silkworm, Bombyx mori.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bombyx; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Cells, Cultured; Colforsin; Cyclic AMP; Dihydropyridines; Exocrine Glands; Kinetics; Larva; Signal Transduction | 2003 |
Modulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Calcium Channel Agonists; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Cricetinae; Dihydropyridines; Electrophysiology; Enzyme Inhibitors; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Okadaic Acid; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rabbits; Serine; Threonine; Time Factors; Transfection | 2003 |
Modulation of manganese currents by 1, 4-dihydropyridines, isoproterenol and forskolin in rabbit ventricular cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic beta-Agonists; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Colforsin; Cyclic AMP; Dihydropyridines; Electrophysiology; Heart Ventricles; In Vitro Techniques; Ion Channel Gating; Ion Channels; Isoproterenol; Manganese; Membrane Potentials; Myocardium; Myocytes, Cardiac; Nitrendipine; Patch-Clamp Techniques; Rabbits; Signal Transduction | 2003 |
Cav1.4alpha1 subunits can form slowly inactivating dihydropyridine-sensitive L-type Ca2+ channels lacking Ca2+-dependent inactivation.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amino Acid Sequence; Barium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cloning, Molecular; Dihydropyridines; Humans; Ion Channel Gating; Isradipine; Kidney; Molecular Sequence Data; Patch-Clamp Techniques; Protein Subunits; Sequence Homology, Amino Acid; Transfection | 2003 |
L-type calcium channel activation up-regulates the mRNAs for two different sodium channel alpha subunits (Nav1.2 and Nav1.3) in rat pituitary GH3 cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Brain; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Dihydropyridines; Drug Interactions; Gene Expression Regulation; NAV1.2 Voltage-Gated Sodium Channel; NAV1.3 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Nimodipine; Nucleic Acid Amplification Techniques; Pituitary Gland; Protein Subunits; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Sodium Channels; Up-Regulation | 2003 |
Intraglomerular inhibition: signaling mechanisms of an olfactory microcircuit.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Bicuculline; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Signaling; Chelating Agents; Dendrites; Diagnostic Imaging; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Conduction; Neural Inhibition; Neural Networks, Computer; Neurons; Nickel; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phosphinic Acids; Potassium; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Valine | 2005 |
The actions of azelnidipine, a dihydropyridine-derivative Ca antagonist, on voltage-dependent Ba2+ currents in guinea-pig vascular smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azetidinecarboxylic Acid; Barium; Calcium Channel Blockers; Dihydropyridines; Female; Guinea Pigs; Ion Channel Gating; Male; Muscle, Smooth, Vascular | 2006 |
Maturation of rat cerebellar Purkinje cells reveals an atypical Ca2+ channel current that is inhibited by omega-agatoxin IVA and the dihydropyridine (-)-(S)-Bay K8644.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebellar Cortex; Dihydropyridines; Male; Membrane Potentials; omega-Agatoxin IVA; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Wistar | 2007 |
Synthesis and docking studies of new 1,4-dihydropyridines containing 4-(5)-Chloro-2-ethyl-5-(4)-imidazolyl substituent as novel calcium channel agonist.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Binding Sites; Calcium Channel Agonists; Calcium Channels; Computer-Aided Design; Databases, Protein; Dihydropyridines; Drug Design; Ligands; Models, Molecular; Molecular Structure; Protein Conformation; Software; Structure-Activity Relationship | 2009 |
The inhibitor of connexin Cx36 channels, mefloquine, inhibits voltage-dependent Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Connexins; Dihydropyridines; Gap Junction delta-2 Protein; Glucose; Insulin Secretion; Insulin-Secreting Cells; Ion Channel Gating; Mefloquine; Mice; Nisoldipine; Potassium Chloride; Tolbutamide | 2018 |
Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amlodipine; Binding Sites; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cryoelectron Microscopy; Dihydropyridines; Molecular Dynamics Simulation; Nanostructures; Protein Structure, Tertiary; Stereoisomerism | 2021 |
Mechanisms of dihydropyridine agonists and antagonists in view of cryo-EM structures of calcium and sodium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Asparagine; Calcium; Cryoelectron Microscopy; Dihydropyridines; Isoleucine; Nitrogen Dioxide; Sodium Channels | 2023 |