Compounds > bay h 4502

bay h 4502 and warfarin

bay h 4502 has been researched along with warfarin in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Halpert, JR; Hernandez, CE; Kumar, S; Liu, H1
Gay, SC; Halpert, JR; Jang, HH; Stout, CD; Wilderman, PR; Zhang, Q1

Other Studies

4 other study(ies) available for bay h 4502 and warfarin

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme.
    Archives of biochemistry and biophysics, 2006, Nov-01, Volume: 455, Issue:1

    Topics: Amino Acid Substitution; Amino Acids; Animals; Aryl Hydrocarbon Hydroxylases; Catalysis; Catalytic Domain; Chromatography, Thin Layer; Coumarins; Crystallization; Crystallography, X-Ray; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Hydroxylation; Imidazoles; Kinetics; Ligands; Models, Molecular; Protein Binding; Stereoisomerism; Substrate Specificity; Testosterone

2006
Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme.
    The FEBS journal, 2012, Volume: 279, Issue:9

    Topics: Aryl Hydrocarbon Hydroxylases; Coumarins; Crystallography, X-Ray; Cytochrome P450 Family 2; Enzyme Stability; Imidazoles; Ligands; Molecular Dynamics Simulation; Mutagenesis, Site-Directed

2012