Compounds > bay h 4502

bay h 4502 and abiraterone

bay h 4502 has been researched along with abiraterone in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brodie, AM; Clement, OO; Freeman, CM; Handratta, VD; Hartmann, RW; Njar, VC; Vasaitis, TS1
Bartels, M; Hartmann, RW; Hu, Q; Jahn-Hoffmann, K; Lauterbach, T; Müller-Vieira, U; Negri, M; Olgen, S; Zhuang, Y1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

3 other study(ies) available for bay h 4502 and abiraterone

ArticleYear
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
    Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12

    Topics: Algorithms; Antineoplastic Agents; Azoles; Binding Sites; Enzyme Inhibitors; Humans; Hydrogen Bonding; Male; Models, Molecular; Prostatic Neoplasms; Protein Binding; Quantitative Structure-Activity Relationship; Steroid 17-alpha-Hydroxylase; Steroids

2003
Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge.
    Bioorganic & medicinal chemistry, 2008, Aug-15, Volume: 16, Issue:16

    Topics: Animals; Binding Sites; Biphenyl Compounds; Enzyme Inhibitors; Humans; Imidazoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Protein Structure, Secondary; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Steroid 17-alpha-Hydroxylase; Testosterone

2008
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013