bam-22p and arginylphenylalaninamide

bam-22p has been researched along with arginylphenylalaninamide* in 1 studies

Other Studies

1 other study(ies) available for bam-22p and arginylphenylalaninamide

Article	Year
Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors. Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21 A series of Arg-Phe-NH2 peptidomimetics containing an Arg mimetic were synthesized and tested as agonists of human MrgX1, rat MrgC, and mouse MrgC11 receptors. As predicted from the previously established species specificity, these peptidomimetics were found to be devoid of MrgX1 agonist activity. In contrast, these compounds acted as agonists of MrgC and/or MrgC11 with varying degrees of potency. These new peptidomimetics should complement the existing small molecule human MrgX1 agonists and enhance our ability to assess the therapeutic utility of targeting Mrg receptors in rodent models. Topics: Animals; HEK293 Cells; Humans; Mice; Neuropeptides; Peptidomimetics; Protein Binding; Rats; Receptors, G-Protein-Coupled; Small Molecule Libraries; Transfection	2014

Article

Year

Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors.

Bioorganic & medicinal chemistry, 2014, Nov-01, Volume: 22, Issue:21

A series of Arg-Phe-NH2 peptidomimetics containing an Arg mimetic were synthesized and tested as agonists of human MrgX1, rat MrgC, and mouse MrgC11 receptors. As predicted from the previously established species specificity, these peptidomimetics were found to be devoid of MrgX1 agonist activity. In contrast, these compounds acted as agonists of MrgC and/or MrgC11 with varying degrees of potency. These new peptidomimetics should complement the existing small molecule human MrgX1 agonists and enhance our ability to assess the therapeutic utility of targeting Mrg receptors in rodent models.

Topics: Animals; HEK293 Cells; Humans; Mice; Neuropeptides; Peptidomimetics; Protein Binding; Rats; Receptors, G-Protein-Coupled; Small Molecule Libraries; Transfection

2014