baicalin has been researched along with wogonin in 86 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 9 (10.47) | 18.2507 |
2000's | 32 (37.21) | 29.6817 |
2010's | 43 (50.00) | 24.3611 |
2020's | 2 (2.33) | 2.80 |
Authors | Studies |
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Kimura, Y; Ogita, Z; Okuda, H | 1 |
Cao, Y; Chen, K; Gu, J; Huang, X; Ji, R; Jiang, H; Liu, T; Luo, X; Pei, G; Wong, BL; Wong, JT; Xue, H | 1 |
Angerhofer, CK; Arnason, JT; Batcha, LL; Bergeron, C; Burdette, JE; Gafner, S; Pezzuto, JM; Reich, J | 1 |
Chen, W; Duan, JA; Guo, J; Liu, L; Lu, Y; Ma, H; Tang, Y | 1 |
Han, C; Kong, L; Lei, J; Li, S; Liu, C; Peng, W; Wang, Z; Xu, X | 1 |
Jin, YS | 1 |
Hsieh, LM; Huang, HC; Wang, HR | 1 |
Lin, SJ; Suen, TT; Tseng, HH; Wen, KC | 1 |
Lin, CC; Shieh, DE | 1 |
Hayashi, K; Kubo, M; Kutsuwa, M; Kyo, R; Nakahata, N; Ohizumi, Y | 1 |
Kwon, IB; Lee, YS; Lee, YW; Park, HH; Park, HJ; Yu, JH | 1 |
Chung, CK; Kim, HM; Kim, KM; Li, E; Moon, EJ; Nam, SY | 1 |
Ishida, S; Miki, H; Okamura, N; Ono, H; Ono, Y; Tanaka, T; Yagi, A; Yano, A | 1 |
Gao, Z; Huang, K; Xu, H; Yang, X | 1 |
Ikemoto, S; Kishimoto, T; Sugimura, K; Wada, S; Yamamoto, K; Yasumoto, R; Yoshida, N | 1 |
Chen, LG; Chen, YC; Lee, TJ; Shen, SC; Yang, LL | 1 |
Chang, WH; Chen, CH; Lu, FJ | 1 |
Cho, S; Cyong, JC; Hong, T; Jin, GB | 1 |
Basnet, P; Cai, SQ; Matsunaga, N; Tani, T; Wang, X; Xie, LH; Yamaji, S; Yang, DY | 1 |
Cui, SL; Feng, XF; He, XR; Hu, SL; Liu, D; Liu, JF; Tang, XJ; Yang, JY; Yang, LX | 1 |
Hayasaka, S; Hayasaka, Y; Matsumoto, M; Nagaki, Y; Nakamura, N; Terasawa, K; Zhang, XY | 1 |
Chang, SF; Hu, SY; Lee, HH; Lee, YH; Wang, CC; Yang, LL | 1 |
Lamer-Zarawska, E; Matkowski, A; Woźniak, D | 1 |
Goodenowe, D; Murch, SJ; Rupasinghe, HP; Saxena, PK | 1 |
Fukazawa, H; Himeji, M; Mimura, A; Nishio, K; Ohtsuki, T; Tanaka, M; Tasaka, K; Ui, S; Yamamoto, H; Yazaki, S | 1 |
Yang, B; Zhou, XN | 1 |
Gao, Z; Gong, Y; Li, H; Xu, H; Zhao, Y | 1 |
Becker, LB; Chang, WT; Li, J; McEntee, E; Mehendale, SR; Shao, ZH; Vanden Hoek, TL; Yuan, CS | 1 |
Dong, XP; Feng, YL; Yu, BY | 1 |
Jeong, DW; Ji, HY; Kim, YC; Kim, YH; Lee, HS; Paek, IB; Sohn, DH | 1 |
Chen, H; Chen, X; Hu, Z; Qi, S; Tang, J; Tian, K; Zhang, H | 1 |
Cheng, Y; Gong, Y; Lin, Z; Yu, K | 1 |
Jeong, DW; Kim, YC; Kim, YH; Lee, HS; Park, ES; Sohn, DH | 1 |
Heo, HJ; Kang, SS; Kim, YS; Lee, CJ; Lee, HJ; Seo, UK; Seok, JH; Son, KH | 1 |
Liu, ZM; Ma, YM; Shi, R; Wang, TM; Yan, JC | 1 |
Broncel, M | 1 |
Gao, J; Wang, HZ; Yu, CH; Zhao, GR | 1 |
Kim, C; Lee, DH; Lee, YJ; Zhang, L | 1 |
Goda, Y; Hishida, A; Makino, T; Mizukami, H | 1 |
Chen, JK; He, CM; Li, LC; Su, S; Zhou, TS | 1 |
Feng, XF; Ge, XG; Li, H; Li, W; Liu, JY; Yang, B | 1 |
Li-Weber, M | 1 |
Li, XL; Mehendale, SR; Wang, CZ; Wang, QF; Yuan, CS | 1 |
Ji, GE; Kim, HS; Kim, JY; Park, MS; Zheng, H | 1 |
Gao, S; Jin, H; Li, W; You, J; Yu, A; Zhang, H | 1 |
Li, F; Niu, J; Wang, Z; Zhang, Q; Zhu, J | 1 |
Cai, F; Chen, W; Feng, J; Jiang, B; Tao, X; Wei, H; Xu, W | 1 |
Corcoran, O; Gao, J; Hylands, PJ; Zhao, H | 1 |
Liu, Q; Song, J; Yan, L; Yi, J; Zhao, J | 1 |
Kim, YK; Lee, SY; Li, X; Park, NI; Park, SU; Xu, H | 1 |
Chang, YC; Chao, PD; Hou, YC; Ko, MH; Lin, SP; Tsai, SY | 1 |
Huang, CG; Li, ZX; Ma, CH; Sun, ZL; Tang, YH; Wang, GY; Ye, G; Zhu, HY | 1 |
Bi, Y; Liu, Q; Yan, L; Yi, J; Zhao, J | 1 |
Chung, HJ; Islam, MN; Kim, DH; Yoo, HH | 1 |
Cai, BC; Cai, H; Liu, X; Zhuang, YS | 1 |
Ding, Y; Du, LJ; Hu, J; Lei, F; Li, HY; Wan, HJ; Xing, DM; Yuan, ZY; Zhao, S | 1 |
Bi, K; Sun, H; Tong, L; Wan, M; Zhang, L; Zhu, Y | 1 |
Jo, HK; Jung, HJ; Kim, SG; Kim, YK; Poudel, A | 1 |
Guo, H; Liu, J; Yang, X; Zheng, W | 1 |
Calway, TD; Mehendale, SR; Smith, J; Wang, CZ; Wang, Y; Wen, XD; Yu, C; Yuan, CS | 1 |
Calway, T; Li, D; Mao, Y; Nass, R; Qu, F; Wang, CZ; Wang, Y; Yu, C; Yuan, CS; Zhen, Z | 1 |
Cho, JH; Ham, SH; Kim, MS; Kim, TW; Lee, HK; Lim, JH; Song, IB; Yun, HI | 1 |
Chen, L; Li, T; Liang, RX; Wang, YL; Wang, YW; Yang, WP; Zhang, D; Zhang, HH; Zhou, ZM | 1 |
Chan, T; Gee Cheung, FS; Li, Z; Xu, F; Zheng, J; Zhou, F; Zhu, L; Zhuge, H | 1 |
Cao, YX; Dong, JC; Gong, WY; Liu, BJ; Lv, YB; Sun, J; Wu, JF; Wu, X; Zhang, HY | 1 |
Fong, SY; Wong, YC; Zuo, Z | 1 |
Bae, JS; Han, MS; Ku, SK; Kwak, S | 1 |
Bae, JS; Ku, SK; Lee, W | 1 |
Do, CW; To, CH; Xiao, JR | 1 |
Dryś, A; Matkowski, A; Woźniak, D | 1 |
Bae, JS; Ku, SK; Lee, HG | 1 |
Chen, L; Li, T; Wang, YL; Wang, YW; Yang, WP; Zhang, D; Zhang, HH; Zhou, ZM; Zhuang, SX | 1 |
Bae, JS; Ku, SK | 1 |
Dong, ZB; Li, C; Shao, JG | 1 |
Seo, CS; Shin, HK | 1 |
Huang, CY; Huang, ZY; Liu, DD; Pan, BB; Ye, YL; Yu, YP; Zhang, Q | 1 |
Chen, XY; Hill, L; Martin, C; Wang, G; Weng, JK; Xue, H; Zhang, Y; Zhao, Q | 1 |
Sun, C; Wang, H; Wang, Y; Xiao, S | 1 |
Hou, ZY; Hu, HJ; Liu, J; Liu, RX; Miao, XS; Song, GH; Wang, WQ; Wei, SL; Wu, PG; Zhang, XW | 1 |
Fong, SYK; Ho, YC; Li, C; Li, R; Wang, Q; Wong, YC; Xue, H; Zuo, Z | 1 |
Geng, YL; Liu, W; Lv, HH; Wang, X; Yang, F; Zhou, J | 1 |
Song, R; Zhang, Y; Zhang, Z | 1 |
Chunyan, L; Jintao, X; Mingxiang, Z; Peng, L; Quanwei, Y; Shuangxi, W; Yun, J | 1 |
Dong, J; Gong, W; Jiang, S; Li, M; Li, Q; Liu, B; Liu, L; Lu, L; Ma, W; Mohammadtursun, N; Qiu, J; Sun, J; Yan, C; Zhao, Z | 1 |
Chen, DF; Cho, KS; Do, CW; Pan, L; To, CH; Yi, I | 1 |
Bekalarska-Dębek, M; Chanaj-Kaczmarek, J; Cielecka-Piontek, J; Dyba, M; Karpiński, TM; Osmałek, T; Szymańska, E; Winnicka, K | 1 |
4 review(s) available for baicalin and wogonin
Article | Year |
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Recent advances in natural antifungal flavonoids and their derivatives.
Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses | 2019 |
New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin.
Topics: Drugs, Chinese Herbal; Enzyme Inhibitors; Flavanones; Flavonoids; Glucuronidase; Humans; Neoplasms; Phytotherapy; Plant Extracts; Scutellaria baicalensis; Topoisomerase II Inhibitors | 2009 |
Potential therapeutic effects of baicalein, baicalin, and wogonin in ocular disorders.
Topics: Animals; Drugs, Chinese Herbal; Eye Diseases; Flavanones; Flavonoids; Humans; Molecular Structure; Scutellaria baicalensis | 2014 |
Baicalein, Baicalin, and Wogonin: Protective Effects against Ischemia-Induced Neurodegeneration in the Brain and Retina.
Topics: Brain; Flavanones; Flavonoids; Humans; Oxidative Stress; Retina | 2021 |
82 other study(ies) available for baicalin and wogonin
Article | Year |
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Effects of flavonoids isolated from scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells.
Topics: Cell Line; Endothelium, Vascular; Female; Fibrinolysis; Flavonoids; Humans; L-Lactate Dehydrogenase; Plants, Medicinal; Plasminogen Activator Inhibitor 1; Pregnancy; Tissue Plasminogen Activator; Trypsin; Umbilical Veins | 1997 |
3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors.
Topics: Benzodiazepines; Binding Sites; Calorimetry; Flavonoids; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Recombinant Proteins; Static Electricity | 2001 |
Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora.
Topics: Cells, Cultured; Flavones; Flavonoids; Humans; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Receptors, Serotonin; Scutellaria; Serotonin Antagonists; Vermont | 2003 |
Discovery of estrogen receptor α modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells.
Topics: Animals; Cell Line, Tumor; Chemistry, Pharmaceutical; Crystallography, X-Ray; Drug Design; Drugs, Chinese Herbal; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Flavones; Humans; Mice; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Binding; Transfection | 2012 |
Flavone-based natural product agents as new lysine-specific demethylase 1 inhibitors exhibiting cytotoxicity against breast cancer cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; Biological Products; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Flavones; Histone Demethylases; Humans; Membrane Potential, Mitochondrial; Mitochondria; Molecular Structure; Structure-Activity Relationship | 2019 |
Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell.
Topics: Animals; Cell Division; Cells, Cultured; Depression, Chemical; Drugs, Chinese Herbal; Flavanones; Flavonoids; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rabbits; Thymidine | 1994 |
Determination of gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in the traditional Chinese medicinal preparation sann-joong-kuey-jian-tang by high-performance liquid chromatography.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Iridoid Glucosides; Iridoids; Pyrans; Reproducibility of Results; Xanthenes; Xanthones | 1996 |
The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin.
Topics: Animals; Anti-Infective Agents; Carrageenan; Flavanones; Flavonoids; Inflammation; Male; Medicine, Chinese Traditional; Pain Measurement; Rats; Rats, Wistar | 1996 |
Analysis of inhibitory effects of scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Dinoprostone; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavanones; Flavonoids; Glioma; Ionophores; Molecular Sequence Data; Phosphorylation; Prostaglandin Antagonists; Rats; Tumor Cells, Cultured | 1998 |
Induction of quinone reductase by a methanol extract of Scutellaria baicalensis and its flavonoids in murine Hepa 1c1c7 cells.
Topics: Animals; Anticarcinogenic Agents; Base Sequence; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Enzyme Induction; Flavanones; Flavonoids; Mice; Molecular Sequence Data; NAD(P)H Dehydrogenase (Quinone); Tumor Cells, Cultured | 1998 |
The nitric oxide-producing activities of Scutellaria baicalensis.
Topics: Animals; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavanones; Flavonoids; Interferon-gamma; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1999 |
Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, berberine, coptisine, palmatine, jateorrhizine and glycyrrhizin in Kampo medicines by ion-pair high-performance liquid chromatography.
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glycyrrhizic Acid; Medicine, Kampo | 1999 |
Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi.
Topics: Animals; Antioxidants; Binding Sites; Brain; China; Drugs, Chinese Herbal; Electron Spin Resonance Spectroscopy; Flavanones; Flavonoids; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxidation; Mitochondria; NADP; Plants, Medicinal; Rats; Tumor Cells, Cultured | 1999 |
Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines.
Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavanones; Flavonoids; Humans; Male; Mice; Mice, Inbred C3H; Tumor Cells, Cultured | 2000 |
Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide.
Topics: Animals; Antioxidants; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Drug Interactions; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavanones; Flavonoids; Gene Expression; Isoenzymes; Lipopolysaccharides; Macrophages; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Prostaglandin-Endoperoxide Synthases | 2001 |
Different effects of baicalein, baicalin and wogonin on mitochondrial function, glutathione content and cell cycle progression in human hepatoma cell lines.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; DNA, Neoplasm; Drugs, Chinese Herbal; Flavanones; Flavonoids; Flow Cytometry; Glutathione; Humans; Lamiaceae; Medicine, Chinese Traditional; Mitochondria; Molecular Structure; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Evaluation of the anti-inflammatory effect of baicalein on dextran sulfate sodium-induced colitis in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Colitis; Dextran Sulfate; Female; Flavanones; Flavonoids; Inflammation; Lamiaceae; Mice; Mice, Inbred BALB C; Plant Extracts; Plant Roots; Sulfasalazine | 2002 |
Evaluation of variation of acteoside and three major flavonoids in wild and cultivated Scutellaria baicalensis roots by micellar electrokinetic chromatography.
Topics: Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Flavanones; Flavonoids; Glucosides; Phenols; Plant Roots; Scutellaria; Spectrophotometry, Ultraviolet | 2002 |
[Determination of flavone for Scutellaria baicalensis from different areas by HPLC].
Topics: Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Plant Roots; Plants, Medicinal; Quality Control; Scutellaria baicalensis | 2002 |
Effects of baicalin, baicalein, and wogonin on interleukin-6 and interleukin-8 expression, and nuclear factor-kappab binding activities induced by interleukin-1beta in human retinal pigment epithelial cell line.
Topics: Anti-Inflammatory Agents; Cell Line; Cell Survival; Dexamethasone; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Humans; Interleukin-1; Interleukin-6; Interleukin-8; NF-kappa B; Pigment Epithelium of Eye; Polymerase Chain Reaction; RNA, Messenger | 2003 |
Differential effects of natural polyphenols on neuronal survival in primary cultured central neurons against glutamate- and glucose deprivation-induced neuronal death.
Topics: Animals; Brain Ischemia; Calcium Signaling; Cell Survival; Cells, Cultured; Central Nervous System; Drugs, Chinese Herbal; Excitatory Amino Acid Agonists; Female; Flavanones; Flavonoids; Glucose; Glutamic Acid; L-Lactate Dehydrogenase; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide; Phenols; Polyphenols; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Scutellaria baicalensis | 2003 |
Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis georgi.
Topics: Antimutagenic Agents; Antioxidants; Biphenyl Compounds; Flavanones; Flavonoids; Free Radical Scavengers; Glucosides; Hydrazines; Mutagenicity Tests; Picrates; Plant Extracts; Plant Roots; Scutellaria baicalensis | 2004 |
A metabolomic analysis of medicinal diversity in Huang-qin (Scutellaria baicalensis Georgi) genotypes: discovery of novel compounds.
Topics: Antioxidants; Drugs, Chinese Herbal; Flavanones; Flavonoids; Genetic Variation; Melatonin; Scutellaria baicalensis | 2004 |
Difference of growth-inhibitory effect of Scutellaria baicalensis-producing flavonoid wogonin among human cancer cells and normal diploid cell.
Topics: Apoptosis; Cell Cycle; Cell Division; Cell Line; Cell Line, Tumor; Cell Proliferation; Diploidy; DNA Fragmentation; Drugs, Chinese Herbal; Flavanones; Flavonoids; G2 Phase; Growth Inhibitors; Humans; Neoplasms; Plant Extracts; Scutellaria baicalensis | 2007 |
[Determination of contents of the effective ingredients in root of Scutellaria baicalensis by HPLC-ECD].
Topics: China; Cluster Analysis; Ecosystem; Flavanones; Flavonoids; Plant Roots; Plants, Medicinal; Scutellaria baicalensis | 2006 |
Effects of flavonoids extracted from Scutellaria baicalensis Georgi on hemin-nitrite-H2O2 induced liver injury.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Glutathione; Hemin; Humans; Hydrogen Peroxide; Lipid Peroxidation; Liver; Liver Diseases; Microsomes, Liver; Nitrates; Nitrites; Nitrosation; Oxidation-Reduction; Plant Extracts; Proteins; Rats; Scutellaria baicalensis | 2006 |
Cardioprotective effects of grape seed proanthocyanidins, baicalin and wogonin: comparison between acute and chronic treatments.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; Chickens; Flavanones; Flavonoids; Heart; Seeds | 2006 |
[Simultaneous determination of three kinds of components in sanhuang tablets by high-performance liquid chromatography].
Topics: Anthraquinones; Berberine; Chromatography, High Pressure Liquid; Coptis; Drug Combinations; Drugs, Chinese Herbal; Emodin; Flavanones; Flavonoids; Plants, Medicinal; Quality Control; Reproducibility of Results; Rheum; Scutellaria baicalensis; Tablets | 2006 |
Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma.
Topics: Animals; Chromatography, Liquid; Flavanones; Flavonoids; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Scutellaria; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2006 |
Analysis of baicalein, baicalin and wogonin in Scutellariae radix and its preparation by microemulsion electrokinetic chromatography with 1-butyl-3-methylimizolium tetrafluoborate ionic liquid as additive.
Topics: Borates; Chromatography, Micellar Electrokinetic Capillary; Drugs, Chinese Herbal; Flavanones; Flavonoids; Imidazoles; Molecular Structure; Plant Extracts; Reproducibility of Results; Scutellaria baicalensis | 2006 |
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresis.
Topics: 2-Propanol; Acetonitriles; Buffers; Capillary Electrochromatography; China; Drugs, Chinese Herbal; Flavanones; Flavonoids; Models, Statistical; Molecular Structure; Plant Extracts; Quality Control; Reproducibility of Results; Scutellaria baicalensis; Solvents; Time Factors | 2007 |
Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats.
Topics: Administration, Oral; Animals; Chromatography, Liquid; Flavanones; Flavonoids; Gastrointestinal Tract; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Tandem Mass Spectrometry | 2007 |
Effects of baicalin and wogonin on mucin release from cultured airway epithelial cells.
Topics: Animals; Anti-Asthmatic Agents; Cells, Cultured; Cricetinae; Drugs, Chinese Herbal; Epithelial Cells; Flavanones; Flavonoids; Male; Mesocricetus; Mucins; Prostaglandin Antagonists; Respiratory Mucosa; Scutellaria baicalensis | 2007 |
[Pharmacokinetics of flavonoids from xiexin decoction in rats].
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Kidney; Male; Rats; Rats, Sprague-Dawley | 2007 |
[Antiatherosclerotic properties of flavones from the roots of Scutellaria baicalensis Georgi].
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antioxidants; Atherosclerosis; China; Drugs, Chinese Herbal; Flavanones; Flavones; Flavonoids; Free Radical Scavengers; Humans; Japan; Plant Roots; Plants, Medicinal; Scutellaria baicalensis | 2007 |
[Effects of processing and extracting methods on active components in Radix Scutellariae by HPLC analysis].
Topics: Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glucosides; Hot Temperature; Plant Roots; Plants, Medicinal; Reproducibility of Results; Scutellaria baicalensis; Technology, Pharmaceutical | 2007 |
Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cytochromes c; DNA Fragmentation; Epithelial Cells; Flavanones; Flavonoids; Gene Expression Regulation; Humans; Male; Prostate; Proto-Oncogene Proteins; Tumor Suppressor Protein p53 | 2008 |
Comparison of the major flavonoid content of S. baicalensis, S. lateriflora, and their commercial products.
Topics: Dietary Supplements; Flavanones; Flavonoids; Glucuronides; Japan; Plant Extracts; Plant Leaves; Plant Roots; Plant Stems; Scutellaria; Scutellaria baicalensis; Tea | 2008 |
Genetic characterization and phytochemical analysis of wild and cultivated populations of Scutellaria baicalensis.
Topics: Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Genetic Variation; Glucosides; Random Amplified Polymorphic DNA Technique; Scutellaria baicalensis | 2008 |
[Comparative study on chemcial composition between cultivated and wild Scutellariae radix].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Reproducibility of Results; Scutellaria baicalensis; Sensitivity and Specificity | 2008 |
Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Flavanones; Flavonoids; Glucuronates; Humans; Phytotherapy; Plant Extracts; Scutellaria baicalensis | 2010 |
Cloning and expression of beta-glucuronidase from Lactobacillus brevis in E. coli and application in the bioconversion of baicalin and wogonoside.
Topics: Amino Acid Sequence; Cloning, Molecular; Enzyme Stability; Escherichia coli; Flavanones; Flavonoids; Glucosides; Glucuronidase; Hydrogen-Ion Concentration; Levilactobacillus brevis; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity; Temperature; Time Factors | 2009 |
On-line continuous flow ultrasonic extraction coupled with high performance liquid chromatographic separation for determination of the flavonoids from root of Scutellaria baicalensis Georgi.
Topics: Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Flavanones; Flavonoids; Limit of Detection; Online Systems; Particle Size; Plant Roots; Reference Standards; Regression Analysis; Rheology; Scutellaria baicalensis; Solvents; Ultrasonics | 2010 |
[A quantitative method for simultaneous assay of four flavones with one marker in Radix Scutellariae].
Topics: Chromatography, High Pressure Liquid; Flavanones; Flavones; Flavonoids; Glucosides; Plant Extracts; Scutellaria baicalensis | 2009 |
Simultaneous determination of baicalin, baicalein, wogonin, berberine, palmatine and jatrorrhizine in rat plasma by liquid chromatography-tandem mass spectrometry and application in pharmacokinetic studies after oral administration of traditional Chinese
Topics: Administration, Oral; Animals; Berberine; Berberine Alkaloids; Chromatography, Liquid; Coptis; Flavanones; Flavonoids; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley; Scutellaria; Tandem Mass Spectrometry | 2010 |
Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Humans; Least-Squares Analysis; Lung Neoplasms; Magnetic Resonance Spectroscopy; Plant Extracts; Principal Component Analysis; Scutellaria | 2010 |
[Simultaneous determination of five active constitutents in Xiaochaihu Tang by HPLC].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhizic Acid; Indicators and Reagents; Medicine, Chinese Traditional; Rehmannia; Spectrophotometry, Ultraviolet; Technology, Pharmaceutical | 2010 |
Molecular cloning and characterization of phenylalanine ammonia-lyase, cinnamate 4-hydroxylase and genes involved in flavone biosynthesis in Scutellaria baicalensis.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Flavanones; Flavones; Flavonoids; Gene Expression Regulation, Plant; Genes, Plant; Molecular Sequence Data; Organ Specificity; Phenylalanine Ammonia-Lyase; Scutellaria baicalensis; Sequence Alignment; Sequence Analysis, DNA; Time Factors; Trans-Cinnamate 4-Monooxygenase | 2010 |
Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats.
Topics: Administration, Oral; Animals; Brain; Chromatography, Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Kidney; Liver; Lung; Male; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Tandem Mass Spectrometry; Tissue Distribution | 2011 |
Characterization of the multiple absorbed constituents in rats after oral administration of Chai-Huang decoction by liquid chromatography coupled with electrospray-ionization mass spectrometry.
Topics: Administration, Oral; Animals; Bupleurum; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glucuronides; Medicine, Chinese Traditional; Oleanolic Acid; Rats; Saponins; Scutellaria baicalensis; Spectrometry, Mass, Electrospray Ionization | 2010 |
[Study on transportation of Xiaochaihu Tang in Caco-2 cell model].
Topics: Biological Transport, Active; Caco-2 Cells; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhizic Acid; Humans | 2011 |
A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae radix extract.
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Limit of Detection; Quality Control; Reproducibility of Results; Scutellaria baicalensis | 2012 |
[Simultaneous determination of five main index components and specific chromatograms analysis in Xiaochaihu granules].
Topics: Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhetinic Acid; Quality Control; Sensitivity and Specificity | 2012 |
Comparative study of the effect of baicalin and its natural analogs on neurons with oxygen and glucose deprivation involving innate immune reaction of TLR2/TNFα.
Topics: Animals; Antioxidants; Caspase 3; Cell Survival; Flavanones; Flavonoids; Glucose; Glucosides; Immunity, Innate; Neurons; Oxygen; PC12 Cells; Rats; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha | 2012 |
Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry.
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Half-Life; Limit of Detection; Male; Metabolic Clearance Rate; Plant Extracts; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Scutellaria baicalensis; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2012 |
Development of simultaneous analysis for marker constituents in Hwangryunhaedok-tang () and its application in commercial herbal formulas.
Topics: Berberine; Drugs, Chinese Herbal; Flavanones; Flavonoids; Iridoids | 2013 |
[Preparation of flavonoid reference standards from Scutellariae Radix under the guidance of high performance liquid chromatography-mass spectrometry analysis].
Topics: Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Mass Spectrometry; Reference Standards; Scutellaria baicalensis | 2012 |
Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Cyclin A; Cyclin B1; Enzyme Inhibitors; Flavanones; Flavonoids; G2 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Iridoids; Membrane Potential, Mitochondrial; Mitochondria; Phytotherapy; Plant Extracts; S Phase Cell Cycle Checkpoints; Scutellaria baicalensis | 2013 |
Different extraction pretreatments significantly change the flavonoid contents of Scutellaria baicalensis.
Topics: Chemical Fractionation; Chromatography, High Pressure Liquid; Drug Stability; Flavanones; Flavonoids; Glucosides; Hydrogen-Ion Concentration; Kinetics; Phytotherapy; Plant Extracts; Plants, Medicinal; Quality Control; Scutellaria baicalensis; Solvents; Temperature | 2013 |
Assessment of dermal safety of Scutellaria baicalensis aqueous extract topical application on skin hypersensitivity.
Topics: Administration, Topical; Animals; Anti-Allergic Agents; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Flavanones; Flavonoids; Glucosides; Guinea Pigs; Hypersensitivity; Male; Mice; Mice, Inbred BALB C; Plant Extracts; Plant Roots; Plants, Medicinal; Rabbits; Rats; Scutellaria baicalensis; Skin | 2013 |
[LC-MS quantification and pharmacokinetics of the multi-constituents of Huangqin Tang in rat plasma after different single oral doses].
Topics: Administration, Oral; Animals; Chromatography, Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Male; Monoterpenes; Pentacyclic Triterpenes; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization | 2013 |
The inhibitory effects of the bioactive components isolated from Scutellaria baicalensis on the cellular uptake mediated by the essential solute carrier transporters.
Topics: Biological Transport, Active; Cell Line; Flavanones; Flavonoids; Humans; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Plant Extracts; Scutellaria baicalensis; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2013 |
Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Flavanones; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Inflammation; Lung Neoplasms; Neoplasm Metastasis; Nicotine; Plant Extracts; Scutellaria baicalensis | 2014 |
Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies.
Topics: Animals; Brain; Chromatography, Liquid; Flavanones; Flavones; Flavonoids; Glucosides; Glucuronides; Male; Rats; Solid Phase Extraction; Tandem Mass Spectrometry | 2014 |
Vascular barrier protective effects of baicalin, baicalein and wogonin in vitro and in vivo.
Topics: Animals; Capillary Permeability; Cell Movement; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; Flavonoids; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Protective Agents | 2014 |
Anti-inflammatory effects of Baicalin, Baicalein, and Wogonin in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Flavanones; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL | 2015 |
Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix.
Topics: Antioxidants; Flavanones; Flavones; Flavonoids; Free Radical Scavengers; Glucosides; Molecular Structure; Plant Extracts; Plant Roots; Scutellaria baicalensis | 2015 |
Inhibitory effect of baicalin, baicalein and wogonin on secretory group IIA phospholipase A2.
Topics: Animals; Drugs, Chinese Herbal; Flavanones; Flavonoids; Gene Expression Regulation, Enzymologic; Group II Phospholipases A2; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phospholipases A2, Cytosolic | 2015 |
[Pharmacokinetics and pharmacodynamics of huangqin tang in febrile rats].
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, Liquid; Dinoprostone; Drugs, Chinese Herbal; Fever; Flavanones; Flavonoids; Glucosides; Interleukin-1beta; Mass Spectrometry; Monoterpenes; Rats; Tumor Necrosis Factor-alpha | 2014 |
Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Astragalus propinquus; Cell Adhesion Molecules; Diabetes Complications; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucose; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Mice; NF-kappa B; Reactive Oxygen Species; Vasculitis | 2015 |
[Simultaneous determination of seven components in Pudilan Xiaoyan oral liquid by HPLC].
Topics: Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Succinates | 2015 |
HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang.
Topics: Acetonitriles; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glucosides; Glycyrrhizic Acid; Humans; Limit of Detection; Medicine, Korean Traditional; Observer Variation; Pinellia; Plants, Medicinal; Reproducibility of Results; Solvents; Trifluoroacetic Acid; Water | 2016 |
[Screening of Active Fractions from Huanglian Jiedu Decoction against Primary Neuron Injury after Oxygen-Glucose Deprivation].
Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucose; Iridoids; Models, Animal; Neurons; Oxygen; Rats; Reperfusion Injury | 2015 |
A specialized flavone biosynthetic pathway has evolved in the medicinal plant, Scutellaria baicalensis.
Topics: Acyltransferases; Animals; Antioxidants; Apoptosis; Biosynthetic Pathways; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Flavanones; Flavones; Flavonoids; Gene Expression Regulation, Plant; Humans; Mice; Plant Extracts; Plants, Medicinal; Scutellaria baicalensis | 2016 |
Rapid Isolation and Determination of Flavones in Biological Samples Using Zinc Complexation Coupled with High-Performance Liquid Chromatography.
Topics: Apigenin; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Flavanones; Flavones; Flavonoids; Glucosides; Glucuronates; Humans; Plant Components, Aerial; Plant Extracts; Scutellaria baicalensis; Zinc Acetate | 2016 |
Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis.
Topics: Drugs, Chinese Herbal; Flavanones; Flavonoids; Plant Roots; Scutellaria baicalensis | 2017 |
Brain Uptake of Bioactive Flavones in Scutellariae Radix and Its Relationship to Anxiolytic Effect in Mice.
Topics: Animals; Anti-Anxiety Agents; Brain; Flavanones; Flavones; Flavonoids; Glucosides; Male; Maze Learning; Mice; Mice, Inbred ICR; Scutellaria baicalensis; Tandem Mass Spectrometry | 2017 |
[Influence of different germination stage on plant biomass and active compounds of Scutellaria baicalensis germchit].
Topics: Biomass; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Germination; Glucosides; Plant Extracts; Plant Roots; Scutellaria baicalensis; Seedlings | 2016 |
The Influence of Compatibility of Rhubarb and Radix Scutellariae on the Pharmacokinetics of Anthraquinones and Flavonoids in Rat Plasma.
Topics: Animals; Anthraquinones; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Herb-Drug Interactions; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Rheum; Scutellaria baicalensis; Tandem Mass Spectrometry | 2018 |
Rapid and Simultaneous Determination of Three Active Components in Raw and Processed Root Samples of Scutellaria baicalensis by Near-infrared Spectroscopy.
Topics: Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Geography; Least-Squares Analysis; Medicine, Chinese Traditional; Multivariate Analysis; Plant Roots; Scutellaria baicalensis; Spectroscopy, Near-Infrared | 2019 |
Scutellaria Flavonoids Effectively Inhibit the Malignant Phenotypes of Non-small Cell Lung Cancer in an Id1-dependent Manner.
Topics: A549 Cells; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Flavanones; Flavonoids; Guanosine Triphosphate; Humans; Inhibitor of Differentiation Protein 1; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Phenotype; Phosphorylation; Plant Extracts; Scutellaria; Shelterin Complex; Telomere-Binding Proteins | 2019 |
Development and Evaluation of Thermosensitive Hydrogels with Binary Mixture of
Topics: Animals; Chitosan; Drugs, Chinese Herbal; Flavanones; Flavonoids; Hydrogels; Mouth Mucosa; Periodontal Diseases; Plant Extracts; Plant Roots; Scutellaria baicalensis; Swine | 2021 |