baicalin has been researched along with iridoids in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.92) | 18.2507 |
| 2000's | 12 (23.53) | 29.6817 |
| 2010's | 36 (70.59) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, SJ; Suen, TT; Tseng, HH; Wen, KC | 1 |
| Li, Y; Lu, L; Sun, X; Zhang, Z | 1 |
| Fujita, K; Hayashi, A; Kamataki, T; Mogami, A | 1 |
| Bae, HS; Cho, KH; Kim, DH; Kim, JJ; Kim, YS; Moon, SK; Park, EK; Yim, JS | 1 |
| Cheng, Y; Luo, G; Wang, Y; Xin, W; Yan, S | 1 |
| Liang, Q; Liu, Q; Luo, G; Pan, Y; Pang, C; Ran, X; Wang, B | 1 |
| Li, PT; Wang, LY; Wang, YY; Wang, Z; Zhang, ZJ | 1 |
| Li, P; Li, PT; Sun, ZH; Wang, YY; Wang, Z; Zhang, WS; Zhang, XJ; Zhang, ZJ | 1 |
| Lei, P; Li, XZ; Liu, S | 1 |
| Gao, YH; Niu, FL; Pang, H; Shan, ZS; Wang, SR; Yuan, ZZ; Zhu, LQ | 2 |
| Chen, Y; Han, FM; Li, LJ; Li, Y | 1 |
| Hui, JG; Sun, XM; Zhang, ZW; Zhao, XM | 1 |
| Ding, XY; Hao, F; Jiang, Y; Li, YR | 1 |
| Fu, J; Guo, L; Pan, L; Zhu, H | 1 |
| Jing, ZW; Li, M; Li, PT; Liu, J; Wang, LY; Wang, Z; Wu, HL; Yan, ZL; Zhang, ZJ; Zhou, CX; Zhou, J | 1 |
| Chen, Y; Jing, Z; Liu, J; Lv, A; Meng, F; Wang, Y; Wang, Z; Yu, Y; Zhou, C | 1 |
| Jo, HK; Jung, HJ; Kim, SG; Kim, YK; Poudel, A | 1 |
| Li, L; Li, Y; Liu, R; Shan, L; Yuan, X; Zeng, H; Zhang, W | 1 |
| Li, J; Meng, FY; Wang, CM; Wang, YY; Wang, Z; Wu, RG; Zhang, ZJ | 1 |
| Ji, ZQ; Liu, H; Zhang, ZW | 1 |
| Calway, TD; Mehendale, SR; Smith, J; Wang, CZ; Wang, Y; Wen, XD; Yu, C; Yuan, CS | 1 |
| Cheng, W; Li, P; Liu, J; Wang, Y; Zhang, J; Zhang, Z | 1 |
| Chen, Y; Fang, H; Jing, Z; Liu, J; Lv, A; Meng, F; Wang, Y; Wang, Z; Yu, Y | 1 |
| He, F; Liu, M; Pan, L; Qian, Z; Tang, Y; Zhang, Q; Zhu, H | 1 |
| Chen, YY; Fang, H; Jing, ZW; Li, HX; Liu, J; Wang, YY; Wang, Z; Yu, YN; Zhang, YY | 1 |
| Fang, X; Guan, S; Li, W; Liao, P; Liu, L; Wang, B | 2 |
| Liu, JX; Ma, ZT; Yang, XW; Zhang, Y | 1 |
| Lin, LC; Lu, CM; Tsai, TH | 1 |
| Cheung, F; Feng, Y; Hong, M; Lao, L; Nagamatsu, T; Tan, HY; Wang, N | 1 |
| Kim, JH; Kim, OS; Seo, CS; Shin, HK | 1 |
| Dang, H; Li, B; Li, H; Li, K; Liu, J; Wang, H; Wang, P; Wang, Y; Wang, Z; Yu, Y; Zhang, Y | 1 |
| Huang, CY; Huang, ZY; Liu, DD; Pan, BB; Ye, YL; Yu, YP; Zhang, Q | 1 |
| Gao, X; Lu, Z; Peng, L; Qin, L; Song, Y; Wang, Q; Zhang, Q; Zhang, Z | 1 |
| Dang, H; Guo, S; Li, B; Li, H; Liu, J; Wang, L; Wang, Y; Wang, Z; Wu, H; Yu, Y; Zhang, Y | 1 |
| Chen, GR; Dou, DQ; Jing, J; Li, MY; Mackie, B; Wang, J; Zhang, G; Zhang, X | 1 |
| Chen, Y; Kang, R; Li, B; Li, H; Liu, J; Wang, P; Wang, Z; Wu, H; Yu, Y; Zhang, X; Zhang, Y | 1 |
| Kang, RX; Li, B; Liu, J; Wang, PQ; Wang, YY; Wang, Z; Wu, HL; Yu, YN; Zhang, XX; Zhang, YY | 1 |
| Kong, L; Li, P; Liao, S; Lv, Y; Wang, J; Xu, D; Yang, M; Zhang, C; Zhang, Q | 1 |
| Dang, H; Li, B; Li, H; Liu, J; Liu, Q; Wang, P; Wang, Z; Yu, Y; Zhang, X; Zhang, Y | 1 |
| Fu, S; Gao, X; Huang, Z; Liu, H; Liu, Y; Lu, F; Wang, M; Xie, Z; Yu, H; Zhang, Y; Zhang, Z; Zhao, H | 1 |
| Guo, B; Liu, AM; Luo, M; Tan, Z | 1 |
| Fu, X; Kong, L; Wang, J; Yang, M; Zhang, Q | 1 |
| Li, B; Liu, J; Liu, Q; Ni, X; Wang, P; Wang, Y; Wang, Z; Yu, Y; Zhang, X; Zhang, Y | 1 |
| Chen, G; Dou, D; Guo, S; Xu, Y; Zhang, M; Zhang, X | 1 |
| Li, B; Liu, J; Liu, Q; Wang, PQ; Wang, Z; Xu, WJ; Yu, YN; Zhang, YY | 1 |
| Kang, YG; Li, M; Shi, YH; Wang, B; Wang, C; Wu, J | 1 |
| Cheng, HF; Huang, SS; Liu, PY; Tsai, CF; Wang, BC; Wang, DY; Yeh, CC | 1 |
| Cai, Z; Ding, Y; Huang, T; Jin, M; Zhang, T | 1 |
| Li, H; Li, M; Liu, J; Shi, Y; Wang, B; Wang, Y; Yang, H | 1 |
51 other study(ies) available for baicalin and iridoids
| Article | Year |
|---|---|
Determination of gentiopicroside, mangiferin, palmatine, berberine, baicalin, wogonin and glycyrrhizin in the traditional Chinese medicinal preparation sann-joong-kuey-jian-tang by high-performance liquid chromatography.
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Iridoid Glucosides; Iridoids; Pyrans; Reproducibility of Results; Xanthenes; Xanthones | 1996 |
[Comparison of 4 extraction methods for antidotal granules of Coptis].
Topics: Anti-Infective Agents; Berberine; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Iridoids; Pyrans; Technology, Pharmaceutical | 1996 |
Establishment of Salmonella strain expressing catalytically active human UDP-glucuronosyltransferase 1A1 (UGT1A1).
Topics: Animals; Bilirubin; Blotting, Western; Cell Fractionation; DNA Primers; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Flavonoids; Gene Expression; Glucuronates; Glucuronidase; Glucuronosyltransferase; Glycyrrhizic Acid; Humans; Iridoids; Microsomes, Liver; Plasmids; Polymerase Chain Reaction; Pyrans; RNA; Salmonella typhimurium; Transfection | 2000 |
Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora.
Topics: Adult; Chromatography, Thin Layer; Feces; Female; Flavanones; Flavonoids; Ginsenosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; In Vitro Techniques; Iridoid Glycosides; Iridoids; Male; Panax; Plant Extracts; Pyrans; Scutellaria baicalensis; Stereoisomerism | 2004 |
[Simultaneous determination of five groups of components in qingkailing injection by high performance liquid chromatography with photo diode array detector and evaporative light scattering detector].
Topics: Adenosine; Caffeic Acids; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Iridoids; Medicine, Chinese Traditional; Scattering, Radiation; Uridine | 2005 |
Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry.
Topics: Animals; Calibration; Cholic Acid; Chromatography, High Pressure Liquid; Deoxycholic Acid; Flavonoids; Iridoids; Male; Pyrans; Rats; Rats, Wistar; Reference Standards; Spectrometry, Mass, Electrospray Ionization | 2006 |
[Pharmacological evaluation of baicalin and jasminoidin and their combination on focal cerebral ischemia-reperfusion injury].
Topics: Animals; Behavior, Animal; Brain; Brain Ischemia; CREB-Binding Protein; Cyclic AMP Response Element-Binding Protein; Drug Combinations; Flavonoids; Gardenia; Injections; Iridoids; Male; Neuroprotective Agents; Plants, Medicinal; Proto-Oncogene Proteins c-akt; Pyrans; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Scutellaria; Signal Transduction | 2006 |
A comparative study on the individual and combined effects of baicalin and jasminoidin on focal cerebral ischemia-reperfusion injury.
Topics: Analysis of Variance; Animals; Brain; Brain Ischemia; Brain-Derived Neurotrophic Factor; Caspase 3; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Iridoids; Male; Neuroprotective Agents; Nimodipine; Pyrans; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Statistics, Nonparametric | 2006 |
[Determination of 3 kinds of components in huanglian jiedu decoction by HPLC under different UV wavelengths].
Topics: Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Iridoids; Plants, Medicinal; Pyrans; Quality Control; Ultraviolet Rays | 2006 |
[Protective action of effective components of Huanglian Jiedu decoction on hypoxia and reoxygenation injury in cultured rat cerebral microvascular endothelial cells].
Topics: Animals; Berberine; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Combinations; Drugs, Chinese Herbal; Endothelial Cells; Flavonoids; Iridoids; Male; Neuroprotective Agents; Oxygen; Plants, Medicinal; Pyrans; Rats; Rats, Sprague-Dawley | 2007 |
[Simultaneous determination of geniposide, baicalin and berberine hydrochloride in Angong Niuhuang pill by RP-HPLC].
Topics: Berberine; Chromatography, High Pressure Liquid; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Iridoids; Materia Medica; Plants, Medicinal; Pyrans | 2007 |
[Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction].
Topics: Antihypertensive Agents; Drug Combinations; Drugs, Chinese Herbal; Eucommiaceae; Flavonoids; Glucosides; Hydrogen-Ion Concentration; Iridoid Glucosides; Iridoids; Leonurus; Plants, Medicinal; Proline; Prunella; Scutellaria baicalensis; Technology, Pharmaceutical; Time Factors; Triterpenes; Uncaria; Ursolic Acid | 2007 |
[Fast and simultaneous determination of four index components in Qingwei Huanglian tablets by RP-HPLC].
Topics: Berberine; Chromatography, High Pressure Liquid; Coptis; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Gardenia; Glycyrrhiza; Glycyrrhizic Acid; Iridoids; Plants, Medicinal; Quality Control; Scutellaria baicalensis; Tablets | 2007 |
[Effect of effective components of huanglian jiedu decoction on hypoxia, reoxygenation injury and the expression of VCAM in cultured rat cerebral microvascular endothelial cells].
Topics: Animals; Berberine; Cell Hypoxia; Cells, Cultured; Cerebrum; Drugs, Chinese Herbal; Endothelium, Vascular; Flavonoids; Gene Expression; Humans; Hypoxia; Iridoids; Male; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vascular Cell Adhesion Molecule-1 | 2008 |
[Preliminary study to investigate dynamic extract process of Huanglian Jiedu Tang and the mechanism of subsidence produce].
Topics: Alkaloids; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavones; Flavonoids; Fractional Precipitation; Iridoids; Plants, Medicinal | 2010 |
Comparison of the network structural characteristics of calcium signaling pathway in cerebral ischemia after intervention by different components of Chinese medicine.
Topics: Animals; Brain Ischemia; Calcium Signaling; Drugs, Chinese Herbal; Flavonoids; Iridoids; Male; Mice; Nimodipine | 2011 |
Variations in target gene expression and pathway profiles in the mouse hippocampus following treatment with different effective compounds for ischemia-reperfusion injury.
Topics: Animals; ATP-Binding Cassette Transporters; Capillary Electrochromatography; Cerebral Infarction; Cholic Acid; Drugs, Chinese Herbal; Flavonoids; Gene Expression; Hippocampus; Iridoids; Male; Mice; Microarray Analysis; Mitogen-Activated Protein Kinases; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA; Signal Transduction | 2012 |
Development of simultaneous analysis for marker constituents in Hwangryunhaedok-tang () and its application in commercial herbal formulas.
Topics: Berberine; Drugs, Chinese Herbal; Flavanones; Flavonoids; Iridoids | 2013 |
The different inhibitory effects of Huang-Lian-Jie-Du-Tang on cyclooxygenase 2 and 5-lipoxygenase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Berberine; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drugs, Chinese Herbal; Edema; Flavanones; Flavonoids; Iridoids; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Synergism and rules from combination of Baicalin, Jasminoidin and Desoxycholic acid in refined Qing Kai Ling for treat ischemic stroke mice model.
Topics: Animals; Cluster Analysis; Computational Biology; Deoxycholic Acid; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Iridoids; Ischemia; Male; Mice; Models, Statistical; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Principal Component Analysis; Stroke | 2012 |
[Optimization of the extraction process for qingrejiedu oral liquid with synthesizing multiple guidelines grading method].
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavonoids; Gardenia; Iridoids; Plants, Medicinal; Quality Control; Reproducibility of Results; Scutellaria baicalensis; Technology, Pharmaceutical | 2012 |
Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chemoprevention; Colorectal Neoplasms; Cyclin A; Cyclin B1; Enzyme Inhibitors; Flavanones; Flavonoids; G2 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Iridoids; Membrane Potential, Mitochondrial; Mitochondria; Phytotherapy; Plant Extracts; S Phase Cell Cycle Checkpoints; Scutellaria baicalensis | 2013 |
Ameliorative effects of a combination of baicalin, jasminoidin and cholic acid on ibotenic acid-induced dementia model in rats.
Topics: Alzheimer Disease; Animals; Cholic Acid; Dementia; Disease Models, Animal; Drug Combinations; Drugs, Chinese Herbal; Flavonoids; Humans; Ibotenic Acid; Iridoids; Male; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Rats | 2013 |
Hierarchical profiles of signaling pathways and networks reveal two complementary pharmacological mechanisms.
Topics: Animals; Brain Ischemia; Flavonoids; Gene Regulatory Networks; Iridoids; Male; Mice; Random Allocation; Signal Transduction; Transcriptome; Ursodeoxycholic Acid | 2013 |
Novel pharmacokinetic studies of the Chinese formula Huang-Lian-Jie-Du-Tang in MCAO rats.
Topics: Animals; Berberine; Berberine Alkaloids; Drugs, Chinese Herbal; Flavanones; Flavonoids; Infarction, Middle Cerebral Artery; Iridoids; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2013 |
Convergent and divergent pathways decoding hierarchical additive mechanisms in treating cerebral ischemia-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Infarction, Middle Cerebral Artery; Iridoids; Male; Mice; Mice, Inbred Strains; Microarray Analysis; Molecular Sequence Data; Principal Component Analysis; Reperfusion Injury; Signal Transduction | 2014 |
Oral administration of baicalin and geniposide induces regression of atherosclerosis via inhibiting dendritic cells in ApoE-knockout mice.
Topics: Administration, Oral; Animals; Aorta, Abdominal; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Dendritic Cells; Diet, High-Fat; Flavonoids; Iridoids; Lipids; Male; Mice, Inbred C57BL; Mice, Knockout | 2014 |
Pharmacochemistry and integrated pharmacokinetics of six alkaloids after oral administration of huang-lian-jie-du-tang decoction.
Topics: Administration, Oral; Alkaloids; Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Iridoids; Molecular Structure; Rats; Rats, Sprague-Dawley | 2014 |
Baicalin and geniposide attenuate atherosclerosis involving lipids regulation and immunoregulation in ApoE-/- mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Flavonoids; Forkhead Transcription Factors; Interleukin-10; Iridoids; Lipids; Male; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Phytotherapy; Spleen; T-Lymphocytes, Regulatory; Transforming Growth Factor beta1 | 2014 |
Determination and pharmacokinetic study of gentiopicroside, geniposide, baicalin, and swertiamarin in Chinese herbal formulae after oral administration in rats by LC-MS/MS.
Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, Gel; Drugs, Chinese Herbal; Flavonoids; Iridoid Glucosides; Iridoids; Limit of Detection; Male; Pyrones; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2014 |
Inhibition of eukaryotic elongation factor-2 confers to tumor suppression by a herbal formulation Huanglian-Jiedu decoction in human hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Berberine; Carcinoma, Hepatocellular; Cell Line, Tumor; Drugs, Chinese Herbal; Elongation Factor 2 Kinase; Female; Flavonoids; Humans; Iridoids; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Phytotherapy; Xenograft Model Antitumor Assays | 2015 |
Simultaneous quantification and antiatherosclerosis effect of the traditional Korean medicine, Hwangryunhaedok-tang.
Topics: Animals; Antioxidants; Atherosclerosis; Berberine; Berberine Alkaloids; Biphenyl Compounds; Cell Proliferation; Chromatography, High Pressure Liquid; Coptis; Drugs, Chinese Herbal; Flavonoids; Gardenia; Iridoids; Lipoproteins, LDL; Medicine, Korean Traditional; Muscle, Smooth, Vascular; Phellodendron; Phytotherapy; Picrates; Platelet-Derived Growth Factor; Rats; Regression Analysis; Scutellaria | 2015 |
Variation of pathways and network profiles reveals the differential pharmacological mechanisms of each effective component to treat middle cerebral artery ischemia-reperfusion mice.
Topics: Animals; Flavonoids; Gene Expression Profiling; Gene Regulatory Networks; Iridoids; Ischemia; Male; Metabolic Networks and Pathways; Mice; Microarray Analysis; Middle Cerebral Artery; Neuroprotective Agents; Reperfusion Injury; Ursodeoxycholic Acid | 2016 |
[Screening of Active Fractions from Huanglian Jiedu Decoction against Primary Neuron Injury after Oxygen-Glucose Deprivation].
Topics: Animals; Berberine; Berberine Alkaloids; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucose; Iridoids; Models, Animal; Neurons; Oxygen; Rats; Reperfusion Injury | 2015 |
Pharmacokinetic-Pharmacodynamic Modeling to Study the Antipyretic Effect of Qingkailing Injection on Pyrexia Model Rats.
Topics: Animals; Antipyretics; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fever; Flavonoids; Iridoids; Male; Medicine, Chinese Traditional; Rats; Rats, Sprague-Dawley | 2016 |
Vertical and Horizontal Convergences of Targeting Pathways in Combination Therapy with Baicalin and Jasminoidin for Cerebral Ischemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Gene Expression; Iridoids; Male; Mice; Microarray Analysis; Random Allocation; Reperfusion Injury | 2016 |
The effective components of Huanglian Jiedu Decoction against sepsis evaluated by a lipid A-based affinity biosensor.
Topics: Animals; Berberine; Biosensing Techniques; Drugs, Chinese Herbal; Female; Flavonoids; Interleukin-6; Iridoids; Kidney; Lipid A; Lipopolysaccharides; Liver; Lung; Male; Mice, Inbred BALB C; Myocardium; Sepsis; Tumor Necrosis Factor-alpha | 2016 |
Entropy-based divergent and convergent modular pattern reveals additive and synergistic anticerebral ischemia mechanisms.
Topics: Algorithms; Brain; Brain Ischemia; Drug Delivery Systems; Drug Synergism; Drug Therapy, Combination; Entropy; Flavonoids; Gene Ontology; Gene Regulatory Networks; Humans; Iridoids; Neuroprotective Agents; Transcriptome; Ursodeoxycholic Acid | 2016 |
Quantitative Identification of Compound-Dependent On-Modules and Differential Allosteric Modules From Homologous Ischemic Networks.
Topics: Animals; Brain Ischemia; Flavonoids; Gene Expression Profiling; Gene Regulatory Networks; Humans; Iridoids; Mice; Ursodeoxycholic Acid | 2016 |
The components of Huang-Lian-Jie-Du-Decoction act synergistically to exert protective effects in a rat ischemic stroke model.
Topics: Animals; Berberine; Brain; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Flavonoids; Free Radical Scavengers; Infarction, Middle Cerebral Artery; Iridoids; Male; Metabolomics; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Phytotherapy; Plants, Medicinal; Proton Magnetic Resonance Spectroscopy; Rats, Sprague-Dawley; Reperfusion Injury | 2016 |
Poly-dimensional network comparative analysis reveals the pure pharmacological mechanism of baicalin in the targeted network of mouse cerebral ischemia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Infarction; Disease Models, Animal; Down-Regulation; Drugs, Chinese Herbal; Flavonoids; Gene Expression Profiling; Iridoids; Mice; Reperfusion Injury; Signal Transduction | 2017 |
An integrated strategy by using target tissue metabolomics biomarkers as pharmacodynamic surrogate indices to screen antipyretic components of Qingkaikling injection.
Topics: Administration, Intravenous; Animals; Antipyretics; Drugs, Chinese Herbal; Flavonoids; Hypothalamus; Iridoids; Male; Medicine, Chinese Traditional; Metabolomics; Rats; Rats, Sprague-Dawley | 2017 |
[Screening of effective ingredients of Yinzhihuang injection against cholestasis and their mechanism].
Topics: Alanine Transaminase; Animals; Chlorogenic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cytochrome P450 Family 8; Drugs, Chinese Herbal; Flavonoids; Humans; Iridoids; Liver; Male; Mice; Mice, Inbred ICR | 2016 |
Treatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach.
Topics: Berberine; Brain Ischemia; Drugs, Chinese Herbal; Flavonoids; Humans; Iridoids; Medicine, Chinese Traditional; Metabolomics; Stroke | 2017 |
Network-Wide Screen Identifies Variation of Novel Precise On-Module Targets Using Conformational Modudaoism.
Topics: Allosteric Regulation; Brain Ischemia; Drug Discovery; Flavonoids; Gene Expression Profiling; Gene Regulatory Networks; Humans; Iridoids; Models, Genetic; Ursodeoxycholic Acid | 2018 |
Evaluation of anti-sepsis activity by compounds with high affinity to lipid a from HuanglianJiedu decoction.
Topics: Animals; Berberine; Berberine Alkaloids; Cell Line; Drugs, Chinese Herbal; Flavonoids; Interleukin-6; Iridoids; Lipid A; Lipopolysaccharides; Mice; RAW 264.7 Cells; Sepsis; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Pure mechanistic analysis of additive neuroprotective effects between baicalin and jasminoidin in ischemic stroke mice.
Topics: Animals; Apoptosis; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Hippocampus; Immunity, Innate; Infarction, Middle Cerebral Artery; Iridoids; Male; Mice; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Phenotype; RNA, Messenger; Signal Transduction; Systems Biology; Transcriptome | 2018 |
Network pharmacology identification of mechanisms of cerebral ischemia injury amelioration by Baicalin and Geniposide.
Topics: Animals; Arachidonate 5-Lipoxygenase; Brain Ischemia; Cell Line; Cell Polarity; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Flavonoids; Humans; Iridoids; Mice; Microglia; Molecular Targeted Therapy; Receptors, Leukotriene | 2019 |
Simultaneous quantification of six indicator compounds in Wen-Qing-Yin by high-performance liquid chromatography-diode array detection.
Topics: Berberine; Chromatography, High Pressure Liquid; Coumaric Acids; Drugs, Chinese Herbal; Flavonoids; Furaldehyde; Glucosides; Iridoids; Medicine, Chinese Traditional; Monoterpenes | 2019 |
Enhancement effect of geniposide on solubility and intestinal absorption of baicalin.
Topics: Animals; Drugs, Chinese Herbal; Duodenum; Flavonoids; Intestinal Absorption; Iridoids; Jejunum; Male; Rats; Rats, Sprague-Dawley; Solubility | 2019 |
Baicalin and Geniposide Inhibit Polarization and Inflammatory Injury of OGD/R-Treated Microglia by Suppressing the 5-LOX/LTB4 Pathway.
Topics: Amino Acid Sequence; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Hypoxia; Cell Survival; Cells, Cultured; Epoxide Hydrolases; Flavonoids; Glucose; Humans; Inflammation; Iridoids; Mice; Microglia; Molecular Docking Simulation; Oxygen; Protein Binding; Signal Transduction | 2021 |