Page last updated: 2024-08-24

baicalin and apigenin

baicalin has been researched along with apigenin in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.55)18.2507
2000's7 (31.82)29.6817
2010's11 (50.00)24.3611
2020's3 (13.64)2.80

Authors

AuthorsStudies
Chen, K; Cheng, YC; Hu, CQ; Kilkuskie, RE; Lee, KH; Shi, Q1
Cao, Y; Chen, K; Gu, J; Huang, X; Ji, R; Jiang, H; Liu, T; Luo, X; Pei, G; Wong, BL; Wong, JT; Xue, H1
Broedel, SE; Cihlar, RL; ElSohly, HN; Ferreira, D; Jacob, MR; Joshi, AS; Khan, IA; Khan, SI; Li, XC; Raulli, RE; Walker, LA; Zhang, Z1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Amić, D; Lucić, B1
Ahn, S; Jung, H; Jung, Y; Lee, YH; Lim, Y; Shin, SY; Yong, Y1
Aquino, TM; Araújo-Júnior, JX; da Silva-Júnior, EF; Leoncini, GO; Rodrigues, ÉES1
Jin, YS1
Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC1
Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW1
Cushnie, TP; Hamilton, VE; Lamb, AJ1
Chen, WY; Franek, KJ; Zhang, WD; Zhou, Z1
Chen, X; Xing, J; Zhong, D1
Zgórka, G1
Li, XL; Mehendale, SR; Wang, CZ; Wang, QF; Yuan, CS1
Chen, C; Cui, LJ; Dou, YH; Huang, Y; Huo, K; Wang, JM; Zhan, WH1
Kimura, W; Miura, N; Sato, E; Wu, YX1
He, B; Yang, SY; Zhang, Y1
Huang, P; Huang, XQ; Liang, YE; Mo, ZZ; Su, JY; Su, ZR; Wang, YH; Wu, DW; Wu, XL; Xie, JH; Yu, XD; Zeng, HF; Zheng, RB; Zheng, YF1
Sun, C; Wang, H; Wang, Y; Xiao, S1
Li, P; Liu, B; Liu, J; Liu, K; Qi, LW; Xiao, N; Yang, LL1
Gao, S; Hu, M; Li, L; Tu, Y; Wang, L; Zhou, L1

Reviews

2 review(s) available for baicalin and apigenin

ArticleYear
The medicinal chemistry of Chikungunya virus.
    Bioorganic & medicinal chemistry, 2017, 08-15, Volume: 25, Issue:16

    Topics: Animals; Antiviral Agents; Biological Products; Chemistry, Pharmaceutical; Chikungunya Fever; Chikungunya virus; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017
Recent advances in natural antifungal flavonoids and their derivatives.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses

2019

Other Studies

20 other study(ies) available for baicalin and apigenin

ArticleYear
Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.
    Journal of natural products, 1994, Volume: 57, Issue:1

    Topics: Antiviral Agents; Cells, Cultured; Flavonoids; Galactosides; HIV-1; Humans; Mass Spectrometry; Medicine, Chinese Traditional; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Virus Replication; Zidovudine

1994
3D-QSAR model of flavonoids binding at benzodiazepine site in GABAA receptors.
    Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12

    Topics: Benzodiazepines; Binding Sites; Calorimetry; Flavonoids; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Protein Structure, Secondary; Protein Subunits; Quantitative Structure-Activity Relationship; Receptors, GABA-A; Recombinant Proteins; Static Electricity

2001
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.
    Journal of natural products, 2002, Volume: 65, Issue:12

    Topics: Antifungal Agents; Candida albicans; Combretaceae; Cryptococcus neoformans; Enzyme Inhibitors; Fatty Acid Synthases; Inhibitory Concentration 50; Isoflavones; Melastomataceae; Molecular Structure; Moraceae; Paspalum; Plants, Medicinal; Saccharomyces cerevisiae; Structure-Activity Relationship; Tannins; Triterpenes

2002
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships.
    Chemical biology & drug design, 2015, Volume: 85, Issue:5

    Topics: Apoptosis; Aurora Kinase A; Aurora Kinase B; Aurora Kinase C; Binding Sites; Chromones; Eriocaulaceae; Flavones; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; M Phase Cell Cycle Checkpoints; Microscopy, Fluorescence; Molecular Docking Simulation; Phosphorylation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Quantitative Structure-Activity Relationship

2015
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
    Journal of natural products, 2020, 05-22, Volume: 83, Issue:5

    Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure

2020
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
    Journal of medicinal chemistry, 2021, 12-09, Volume: 64, Issue:23

    Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors

2021
Assessment of the antibacterial activity of selected flavonoids and consideration of discrepancies between previous reports.
    Microbiological research, 2003, Volume: 158, Issue:4

    Topics: Anti-Infective Agents; Apigenin; Drug Resistance, Bacterial; Escherichia coli; Flavonoids; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus

2003
In vitro studies of baicalin alone or in combination with Salvia miltiorrhiza extract as a potential anti-cancer agent.
    International journal of oncology, 2005, Volume: 26, Issue:1

    Topics: Antineoplastic Agents; Apigenin; Camellia sinensis; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Flavonoids; Glucuronates; Humans; Neoplasms; Salvia miltiorrhiza

2005
Stability of baicalin in biological fluids in vitro.
    Journal of pharmaceutical and biomedical analysis, 2005, Sep-15, Volume: 39, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apigenin; Calibration; Chemistry, Pharmaceutical; Chromatography, Liquid; Drug Industry; Electromagnetic Fields; Electron Spin Resonance Spectroscopy; Flavonoids; Glucuronates; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Liver; Male; Mass Spectrometry; Models, Chemical; Oxidation-Reduction; Phenols; Rats; Rats, Wistar; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Temperature; Time Factors

2005
Retention behavior of silica-bonded and novel polymeric reversed-phase sorbents in studies on flavones as chemotaxonomic markers of Scutellaria L. genus.
    Journal of chromatography. A, 2006, Jul-07, Volume: 1120, Issue:1-2

    Topics: Apigenin; Chemotactic Factors; Chromatography, High Pressure Liquid; Flavones; Flavonoids; Luteolin; Molecular Structure; Plant Extracts; Polymers; Scutellaria; Silicon Dioxide

2006
Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Flavanones; Flavonoids; Glucuronates; Humans; Phytotherapy; Plant Extracts; Scutellaria baicalensis

2010
Comparative studies on interactions of baicalein, baicalin and scutellarin with lysozyme.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:12

    Topics: Animals; Anti-Infective Agents; Apigenin; Chickens; Enzyme Inhibitors; Flavanones; Flavonoids; Glucuronates; Muramidase; Pantothenic Acid; Protein Binding; Spectrometry, Fluorescence

2011
Baicalin and scutellarin are proteasome inhibitors that specifically target chymotrypsin-like catalytic activity.
    Phytotherapy research : PTR, 2013, Volume: 27, Issue:9

    Topics: Animals; Apigenin; Apoptosis; Cell Line, Tumor; Cell Survival; Chymotrypsin; Erigeron; Female; Flavonoids; Glucuronates; Humans; Liver; Mice; Mice, Inbred ICR; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Scutellaria baicalensis

2013
[A new method of calibration and positioning in quantitative analysis of multicomponents by single marker].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2012, Volume: 47, Issue:12

    Topics: Apigenin; Calibration; Chlorogenic Acid; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glucuronates; Glycosides; Reproducibility of Results

2012
Biological evaluation and molecular docking of baicalin and scutellarin as Helicobacter pylori urease inhibitors.
    Journal of ethnopharmacology, 2015, Mar-13, Volume: 162

    Topics: Apigenin; Cell Line; Cell Survival; Flavonoids; Glucuronates; Helicobacter pylori; Humans; Molecular Docking Simulation; Urease

2015
Rapid Isolation and Determination of Flavones in Biological Samples Using Zinc Complexation Coupled with High-Performance Liquid Chromatography.
    Molecules (Basel, Switzerland), 2016, Aug-16, Volume: 21, Issue:8

    Topics: Apigenin; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Flavanones; Flavones; Flavonoids; Glucosides; Glucuronates; Humans; Plant Components, Aerial; Plant Extracts; Scutellaria baicalensis; Zinc Acetate

2016
Differential regulation of baicalin and scutellarin on AMPK and Akt in promoting adipose cell glucose disposal.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; AMP-Activated Protein Kinases; Animals; Apigenin; Enzyme Activation; Flavonoids; Glucose; Glucuronates; Hypoglycemic Agents; Mice; Proto-Oncogene Proteins c-akt; Scutellaria baicalensis

2017
Development and validation of an LC-MS/MS method for the quantification of flavonoid glucuronides (wogonoside, baicalin, and apigenin-glucuronide) in the bile and blood samples: Application to a portal vein infusion study.
    Analytical biochemistry, 2020, 07-15, Volume: 601

    Topics: Animals; Apigenin; Bile; Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Glucosides; Male; Portal Vein; Rats; Rats, Wistar; Tandem Mass Spectrometry

2020