Page last updated: 2024-08-24

baicalin and 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one

baicalin has been researched along with 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's10 (62.50)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Kimura, Y; Ogita, Z; Okuda, H1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Hayashi, K; Kubo, M; Kutsuwa, M; Kyo, R; Nakahata, N; Ohizumi, Y1
Jeong, DW; Ji, HY; Kim, YC; Kim, YH; Lee, HS; Paek, IB; Sohn, DH1
Jeong, DW; Kim, YC; Kim, YH; Lee, HS; Park, ES; Sohn, DH1
Baek, NI; Joh, EH; Kim, DH; Kwak, HY; Trinh, HT1
Chen, MC; Eibl, G; Go, VL; Harris, DM; Lu, QY; Moro, A; Zhang, L1
Bi, K; Sun, H; Tong, L; Wan, M; Zhang, L; Zhu, Y1
Guo, H; Liu, J; Yang, X; Zheng, W1
Chen, L; Li, T; Liang, RX; Wang, YL; Wang, YW; Yang, WP; Zhang, D; Zhang, HH; Zhou, ZM1
Fong, SY; Wong, YC; Zuo, Z1
Chen, L; Li, T; Wang, YL; Wang, YW; Yang, WP; Zhang, D; Zhang, HH; Zhou, ZM; Zhuang, SX1
Hou, ZY; Hu, HJ; Liu, J; Liu, RX; Miao, XS; Song, GH; Wang, WQ; Wei, SL; Wu, PG; Zhang, XW1
Fong, SYK; Ho, YC; Li, C; Li, R; Wang, Q; Wong, YC; Xue, H; Zuo, Z1
Cai, ML; Chu, XL; Cui, ZQ; Li, HX; Su, JQ; Wu, SC; Wu, ZM; Yu, ZJ; Zhang, LY; Zhang, ZJ1
Hemantha, HP; Majeed, M; Nagabhushanam, K; Ramanujam, R1

Other Studies

16 other study(ies) available for baicalin and 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one

ArticleYear
Effects of flavonoids isolated from scutellariae radix on fibrinolytic system induced by trypsin in human umbilical vein endothelial cells.
    Journal of natural products, 1997, Volume: 60, Issue:6

    Topics: Cell Line; Endothelium, Vascular; Female; Fibrinolysis; Flavonoids; Humans; L-Lactate Dehydrogenase; Plants, Medicinal; Plasminogen Activator Inhibitor 1; Pregnancy; Tissue Plasminogen Activator; Trypsin; Umbilical Veins

1997
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Analysis of inhibitory effects of scutellariae radix and baicalein on prostaglandin E2 production in rat C6 glioma cells.
    The American journal of Chinese medicine, 1998, Volume: 26, Issue:3-4

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Arachidonic Acid; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Dinoprostone; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavanones; Flavonoids; Glioma; Ionophores; Molecular Sequence Data; Phosphorylation; Prostaglandin Antagonists; Rats; Tumor Cells, Cultured

1998
Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006, Dec-05, Volume: 844, Issue:2

    Topics: Animals; Chromatography, Liquid; Flavanones; Flavonoids; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Scutellaria; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2006
Pharmacokinetics of baicalein, baicalin and wogonin after oral administration of a standardized extract of Scutellaria baicalensis, PF-2405 in rats.
    Archives of pharmacal research, 2007, Volume: 30, Issue:2

    Topics: Administration, Oral; Animals; Chromatography, Liquid; Flavanones; Flavonoids; Gastrointestinal Tract; Male; Plant Extracts; Rats; Rats, Sprague-Dawley; Scutellaria baicalensis; Tandem Mass Spectrometry

2007
Anti-pruritic effect of baicalin and its metabolites, baicalein and oroxylin A, in mice.
    Acta pharmacologica Sinica, 2010, Volume: 31, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Antipruritics; Feces; Flavanones; Flavonoids; Guinea Pigs; Histamine; Histamine Antagonists; Intestines; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Phytotherapy; Pruritus; Scutellaria baicalensis; Streptomycin; Tetracycline

2010
Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts.
    Pancreas, 2012, Volume: 41, Issue:4

    Topics: Animals; Biological Availability; Cell Line, Tumor; Chromatography, High Pressure Liquid; Diet; Flavanones; Flavonoids; Mice; Mice, Nude; Pancreas; Pancreatic Neoplasms; Plant Extracts; Plant Roots; Random Allocation; Scutellaria baicalensis

2012
Simultaneous determination of baicalin, wogonoside, baicalein, wogonin, oroxylin A and chrysin of Radix scutellariae extract in rat plasma by liquid chromatography tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2012, Volume: 70

    Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, Liquid; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Half-Life; Limit of Detection; Male; Metabolic Clearance Rate; Plant Extracts; Rats; Rats, Wistar; Reference Standards; Reproducibility of Results; Scutellaria baicalensis; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2012
[Preparation of flavonoid reference standards from Scutellariae Radix under the guidance of high performance liquid chromatography-mass spectrometry analysis].
    Se pu = Chinese journal of chromatography, 2012, Volume: 30, Issue:7

    Topics: Chromatography, High Pressure Liquid; Flavanones; Flavonoids; Mass Spectrometry; Reference Standards; Scutellaria baicalensis

2012
[LC-MS quantification and pharmacokinetics of the multi-constituents of Huangqin Tang in rat plasma after different single oral doses].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:6

    Topics: Administration, Oral; Animals; Chromatography, Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavanones; Flavonoids; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Male; Monoterpenes; Pentacyclic Triterpenes; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization

2013
Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 97

    Topics: Animals; Brain; Chromatography, Liquid; Flavanones; Flavones; Flavonoids; Glucosides; Glucuronides; Male; Rats; Solid Phase Extraction; Tandem Mass Spectrometry

2014
[Pharmacokinetics and pharmacodynamics of huangqin tang in febrile rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:10

    Topics: Administration, Oral; Animals; Area Under Curve; Chromatography, Liquid; Dinoprostone; Drugs, Chinese Herbal; Fever; Flavanones; Flavonoids; Glucosides; Interleukin-1beta; Mass Spectrometry; Monoterpenes; Rats; Tumor Necrosis Factor-alpha

2014
Distribution patterns of the contents of five biologically activate ingredients in the root of Scutellaria baicalensis.
    Chinese journal of natural medicines, 2017, Volume: 15, Issue:2

    Topics: Drugs, Chinese Herbal; Flavanones; Flavonoids; Plant Roots; Scutellaria baicalensis

2017
Brain Uptake of Bioactive Flavones in Scutellariae Radix and Its Relationship to Anxiolytic Effect in Mice.
    Molecular pharmaceutics, 2017, 09-05, Volume: 14, Issue:9

    Topics: Animals; Anti-Anxiety Agents; Brain; Flavanones; Flavones; Flavonoids; Glucosides; Male; Maze Learning; Mice; Mice, Inbred ICR; Scutellaria baicalensis; Tandem Mass Spectrometry

2017
Baicalin protects mice against Salmonella typhimurium infection via the modulation of both bacterial virulence and host response.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2018, Sep-15, Volume: 48

    Topics: Animals; Anti-Bacterial Agents; Caco-2 Cells; Flavanones; Flavonoids; Humans; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Plant Extracts; Salmonella Infections, Animal; Salmonella typhimurium; Scutellaria; Virulence

2018
An unambiguous and practical synthesis of Oroxylin A: a commonly misidentified flavone.
    Natural product research, 2021, Volume: 35, Issue:9

    Topics: Bignoniaceae; Flavones; Flavonoids; Proton Magnetic Resonance Spectroscopy; Scutellaria baicalensis

2021