baicalein has been researched along with 5-7-dihydroxy-6-methoxy-2-phenylchromen-4-one* in 1 studies
1 other study(ies) available for baicalein and 5-7-dihydroxy-6-methoxy-2-phenylchromen-4-one
Article | Year |
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Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.
A series of 8-aminomethylated derivatives (1a-1j) were prepared by Mannich reaction of oroxylin A (1) with appropriate primary or secondary amines and para-formaldehyde. All the compounds were tested for their alpha-glucosidase inhibition activity against both yeast and rat intestinal alpha-glucosidase. Some of the compounds demonstrated significantly better alpha-glucosidase inhibitory activity than the parent compound (oroxylin A). Topics: Animals; Flavonoids; Glycoside Hydrolase Inhibitors; Intestines; Rats; Saccharomyces cerevisiae; Structure-Activity Relationship | 2008 |