baicalein and 5-7-dihydroxy-6-methoxy-2-phenylchromen-4-one

baicalein has been researched along with 5-7-dihydroxy-6-methoxy-2-phenylchromen-4-one* in 1 studies

Other Studies

1 other study(ies) available for baicalein and 5-7-dihydroxy-6-methoxy-2-phenylchromen-4-one

ArticleYear
Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.
    Bioorganic & medicinal chemistry letters, 2008, Mar-01, Volume: 18, Issue:5

    A series of 8-aminomethylated derivatives (1a-1j) were prepared by Mannich reaction of oroxylin A (1) with appropriate primary or secondary amines and para-formaldehyde. All the compounds were tested for their alpha-glucosidase inhibition activity against both yeast and rat intestinal alpha-glucosidase. Some of the compounds demonstrated significantly better alpha-glucosidase inhibitory activity than the parent compound (oroxylin A).

    Topics: Animals; Flavonoids; Glycoside Hydrolase Inhibitors; Intestines; Rats; Saccharomyces cerevisiae; Structure-Activity Relationship

2008