baclofen and tizanidine

baclofen has been researched along with tizanidine in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (23.94)	18.7374
1990's	12 (16.90)	18.2507
2000's	18 (25.35)	29.6817
2010's	21 (29.58)	24.3611
2020's	3 (4.23)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Evans, RH; Long, SK; Siarey, RJ	1
Milanov, IG	1
Dietz, V	1
Cerný, R; Jerábek, J; Krejcová, H; Vyskocilová, M	1
Paulig, M; Pellkofer, M	1
Ciblis, D; Medici, M; Pebet, M	1
Rice, GP	2
Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Wüllner, U	1
Boisson, D; Eyssette, M; Rohmer, F; Serratrice, G; Warter, JM	1
Bass, B; Bouchard, S; Cameron, MG; Ebers, GC; Hader, W; Noseworthy, JH; Rice, GP; Weinshenker, B	1
Hoogstraten, MC; Minderhoud, JM; van der Ploeg, RJ; van Marle, S; vd Burg, W; Vreeling, A	1
Nordal, HJ; Oftedal, SI; Slettebø, M; Stien, R	1
Delwaide, PJ	1
Davies, J	1
McLellan, DL	1
Davies, J; Johnston, SE	1
Hudgson, P; Newman, PK; Newman, PM; Nogues, M; Weightman, D	1
Muff, S; Smolenski, C; Smolenski-Kautz, S	1
Corston, RN; Godwin-Austen, RB; Johnson, F	1
Hassan, N; McLellan, DL	1
Evans, RH; Long, SK; Siarey, RJ; Tulp, MT	1
Davis, C; Emre, M; Groves, L; Lataste, X	1
Skoog, B	1
Brenner, R; Hyman, N; Knobler, R; O'Brien, M; Stephan, T	1
Groves, L; Novack, GD; Shah, J; Shellenberger, MK	1
Goodkin, DE; Kita, M	1
Adone, R; Pagliacci, C; Taricco, M; Telaro, E	1
Noth, J	1
Autti-Rämö, I	1
Schapiro, RT	1
Rösche, J	1
Anderson, PM; Lloyd, AC; Rushton, DN	1
Al-Shahrani, AM	1
Freitag, FG	1
Yelnik, AP	1
Das, SK; Guha, G; Misra, AK; Ray, BK	1
Patel, DR; Soyode, O	1
Adone, R; Pagliacci, MC; Taricco, M; Telaro, E	1
He, L; Wu, B; Zhou, M	1
Jacobs, BW; Saulino, M	1
Awan, S; Dai, AI; Wasay, M	1
Bensmail, D; Chaleat-Valayer, E; Decq, P; Dehail, P; Dumarcet, N; Marque, P; Parratte, B; Pellas, F; Quentin, V; Rousseaux, M; Simon, O; Trocello, JM; Uzzan, M; Yelnik, AP	1
Benecke, R; Patejdl, R	1
Kuks, JB; Lapeyre, E; Meijler, WJ	1
Simon, O; Yelnik, AP	1
Delgado, MR; Tilton, A; Vargus-Adams, J	1
Chen, CL; Chung, CY; Wong, AM	1
Heinzlef, O; Monteil-Roch, I	1
Gillard, P; Graham, GD; Halpern, R; Varon, SF; Zorowitz, RD	1
Chu, VW; Hornby, TG; Schmit, BD	1
Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M	1
Lipták, J	1
Aksoy, SN; Dai, AI; Demiryürek, AT	1
Álvarez-Ossorio, L; Haupts, M; Jonas, A; Vila, C; Witte, K	1
Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P	1
Kouzouna, A; Lindsay, C; Pandyan, AD; Simcox, C	1
Achey, R; Bethoux, F; Dai, L; Jones, J; Lang, M; Lee, BS; Lobel, DA; Machado, AG; Nagel, SJ	1
Fu, X; Li, J; Li, M; Ma, Q; Wang, C; Wang, Y; Wu, H; Yang, W	1
Donato, AA; Hao, D; Olugbodi, A; Udechukwu, N	1
Abouihia, A; Calabrese, A; Cloud, G; Creamer, M; Francisco, GE; Kossmehl, P; Saltuari, L; Ward, AB; Wissel, J; Yochelson, M; Zampolini, M	1
Friedman, BW; Gallagher, EJ; Irizarry, E; Jones, MP; Pearlman, S; Shah, PD; Solorzano, C; Wollowitz, A; Zias, E	1
Centonze, D; Comi, G; Leocani, L; Otero-Romero, S; Solari, A	1
Jones, É; Vlachou, S	1
Broder, BI; DiStasio, C; Hui, RL; Lee, EA; Niu, F; Steinberg, SG; Su Zhang, VR	1

Reviews

27 review(s) available for baclofen and tizanidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Spasticity: therapy of increased reflexes or movement disorder?]. Der Nervenarzt, 1990, Volume: 61, Issue:10 Topics: Baclofen; Clonidine; Combined Modality Therapy; Dantrolene; Diazepam; Glycine; Humans; Locomotion; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Muscles; Phenothiazines; Reflex, Abnormal	1990
Pharmacotherapy of spasticity: some theoretical and practical considerations. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1987, Volume: 14, Issue:3 Suppl Topics: Baclofen; Benzodiazepines; Clonidine; Dantrolene; Humans; Muscle Spasticity; Parasympatholytics	1987
Comparative profile of tizanidine in the management of spasticity. Neurology, 1994, Volume: 44, Issue:11 Suppl 9 Topics: Activities of Daily Living; Baclofen; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus	1994
An approach to switching patients from baclofen to tizanidine. Hospital medicine (London, England : 1998), 1998, Volume: 59, Issue:10 Topics: Baclofen; Clinical Competence; Clonidine; Humans; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Spinal Cord Diseases; Spinal Cord Injuries	1998
Drugs used to treat spasticity. Drugs, 2000, Volume: 59, Issue:3 Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Drug Administration Schedule; Humans; Muscle Relaxants, Central; Muscle Spasticity	2000
Pharmacological interventions for spasticity following spinal cord injury. The Cochrane database of systematic reviews, 2000, Issue:2 Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Parasympatholytics; Spasm; Spinal Cord Injuries	2000
[Treatment of spasticity]. Duodecim; laaketieteellinen aikakauskirja, 1999, Volume: 115, Issue:8 Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Clonidine; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Quality of Life	1999
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis. Current neurology and neuroscience reports, 2001, Volume: 1, Issue:3 Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabinoids; Causalgia; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Dystonia; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mechanoreceptors; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Pain; Physical Therapy Modalities; Receptors, GABA-A; Receptors, GABA-B; Relaxation Therapy; Trigeminal Neuralgia	2001
Anti-spasticity medications. Saudi medical journal, 2003, Volume: 24, Issue:1 Topics: Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Parasympatholytics	2003
Preventative treatment for migraine and tension-type headaches : do drugs having effects on muscle spasm and tone have a role? CNS drugs, 2003, Volume: 17, Issue:6 Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; GABA Agonists; Humans; Migraine Disorders; Muscle Relaxants, Central; Neuromuscular Agents; Tension-Type Headache	2003
[Pharmacology and upper limb poststroke spasticity: a review. International Society of Prosthetics and Orthotics]. Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2004, Volume: 47, Issue:8 Topics: Arm; Baclofen; Botulinum Toxins, Type A; Clonidine; Combined Modality Therapy; Dantrolene; Ergonomics; Ethanol; Humans; Injections, Intramuscular; Injections, Spinal; Muscle Denervation; Muscle Spasticity; Neuromuscular Agents; Neuromuscular Blockade; Phenol; Physical Therapy Modalities; Stroke	2004
Pharmacologic interventions for reducing spasticity in cerebral palsy. Indian journal of pediatrics, 2005, Volume: 72, Issue:10 Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; Clonidine; Dantrolene; Diazepam; Ethanol; Humans; Infant; Injections, Intramuscular; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Phenol; Time Factors	2005
Pharmacological interventions for spasticity following spinal cord injury: results of a Cochrane systematic review. Europa medicophysica, 2006, Volume: 42, Issue:1 Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Spasticity; Randomized Controlled Trials as Topic; Spinal Cord Injuries	2006
Non-antiepileptic drugs for trigeminal neuralgia. The Cochrane database of systematic reviews, 2006, Jul-19, Issue:3 Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia	2006
The pharmacological management of spasticity. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2006, Volume: 38, Issue:6 Topics: Baclofen; Clonidine; Dantrolene; Humans; Muscle Relaxants, Central; Muscle Spasticity	2006
[New therapies for spastic movement disorders]. MMW Fortschritte der Medizin, 2009, Volume: 151 Suppl 3 Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Injections, Intramuscular; Injections, Spinal; Movement Disorders; Muscle Relaxants, Central; Muscle Spasticity; Parasympatholytics; Physical Therapy Modalities; Tolperisone	2009
Spasticity: revisiting the role and the individual value of several pharmacological treatments. NeuroRehabilitation, 2010, Volume: 27, Issue:2 Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Relaxants, Central; Muscle Spasticity; Recovery of Function; Treatment Outcome	2010
Managing spasticity with drugs. European journal of physical and rehabilitation medicine, 2010, Volume: 46, Issue:3 Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Clonidine; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents	2010
Pharmacologic treatment of spasticity in children. Seminars in pediatric neurology, 2010, Volume: 17, Issue:4 Topics: Age Factors; Baclofen; Botulinum Toxins; Child; Clonidine; Dantrolene; Diazepam; Humans; Injections, Spinal; Muscle Spasticity; Neuromuscular Agents	2010
Pharmacotherapy of spasticity in children with cerebral palsy. Journal of the Formosan Medical Association = Taiwan yi zhi, 2011, Volume: 110, Issue:4 Topics: Baclofen; Benzodiazepines; Cerebral Palsy; Child; Clonidine; Dantrolene; Humans; Muscle Spasticity; Neuromuscular Blocking Agents	2011
[Pharmacological treatment of spasticity in multiple sclerosis]. Revue neurologique, 2012, Volume: 168 Suppl 3 Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin	2012
Non-antiepileptic drugs for trigeminal neuralgia. The Cochrane database of systematic reviews, 2013, Dec-03, Issue:12 Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Randomized Controlled Trials as Topic; Tocainide; Trigeminal Neuralgia	2013
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper. Multiple sclerosis (Houndmills, Basingstoke, England), 2016, Volume: 22, Issue:11 Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol	2016
Pharmacological interventions other than botulinum toxin for spasticity after stroke. The Cochrane database of systematic reviews, 2016, Oct-06, Volume: 10 Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Randomized Controlled Trials as Topic; Stroke; Tolperisone	2016
A mixed treatment comparison on efficacy and safety of treatments for spasticity caused by multiple sclerosis: a systematic review and network meta-analysis. Clinical rehabilitation, 2018, Volume: 32, Issue:6 Topics: Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Transcutaneous Electric Nerve Stimulation	2018
A Critical Review of the Role of the Cannabinoid Compounds Δ Molecules (Basel, Switzerland), 2020, Oct-25, Volume: 25, Issue:21 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Baclofen; Cannabidiol; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Approval; Drug Combinations; Drug Therapy, Combination; Female; Humans; Male; Multiple Sclerosis; Spinal Cord; Treatment Outcome; United States; United States Food and Drug Administration	2020

Trials

15 trial(s) available for baclofen and tizanidine

Article	Year
[Comparative double-blind study of the effectiveness and tolerance of baclofen, tetrazepam and tizanidine in spastic movement disorders of the lower extremities]. Medizinische Klinik (Munich, Germany : 1983), 1989, Jan-15, Volume: 84, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Random Allocation	1989
A double-blind, long-term study of tizanidine ('Sirdalud') in spasticity due to cerebrovascular lesions. Current medical research and opinion, 1989, Volume: 11, Issue:6 Topics: Adult; Aged; Baclofen; Cerebrovascular Disorders; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity	1989
Multi-centre, double-blind trial of a novel antispastic agent, tizanidine, in spasticity associated with multiple sclerosis. Current medical research and opinion, 1988, Volume: 10, Issue:10 Topics: Adult; Aged; Baclofen; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity	1988
Tizanidine versus baclofen in the treatment of spasticity in patients with multiple sclerosis. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1988, Volume: 15, Issue:1 Topics: Adult; Aged; Baclofen; Brain; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity	1988
The treatment of spasticity in multiple sclerosis: a double-blind clinical trial of a new anti-spastic drug tizanidine compared with baclofen. Acta neurologica Scandinavica, 1987, Volume: 75, Issue:3 Topics: Adult; Aged; Baclofen; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity	1987
Tizanidine in the treatment of spasticity. European journal of clinical pharmacology, 1982, Volume: 23, Issue:1 Topics: Adult; Baclofen; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Spasticity; Time Factors	1982
A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis. Current medical research and opinion, 1981, Volume: 7, Issue:6 Topics: Adult; Aged; Baclofen; Chronic Disease; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity	1981
The assessment of drug treatment of spastic gait. Journal of neurology, neurosurgery, and psychiatry, 1981, Volume: 44, Issue:11 Topics: Aged; Baclofen; Clinical Trials as Topic; Clonidine; Female; Gait; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity	1981
A controlled pharmacokinetic evaluation of tizanidine and baclofen at steady state. Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:2 Topics: Adrenergic alpha-Agonists; Adult; Area Under Curve; Baclofen; Biotransformation; Clonidine; Drug Interactions; Half-Life; Humans; Male; Muscle Relaxants, Central	1999
Cost-effectiveness comparison of tizanidine and baclofen in the management of spasticity. PharmacoEconomics, 2002, Volume: 20, Issue:12 Topics: Baclofen; Clonidine; Cost-Benefit Analysis; Humans; Muscle Relaxants, Central; Muscle Spasticity; United Kingdom	2002
Botulinum toxin type A with oral baclofen versus oral tizanidine: a nonrandomized pilot comparison in patients with cerebral palsy and spastic equinus foot deformity. Journal of child neurology, 2008, Volume: 23, Issue:12 Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Chi-Square Distribution; Child; Child, Preschool; Clonidine; Drug Therapy, Combination; Equinus Deformity; Female; Humans; Male; Muscle Relaxants, Central; Neuromuscular Agents; Pilot Projects; Treatment Outcome	2008
Effect of antispastic drugs on motor reflexes and voluntary muscle contraction in incomplete spinal cord injury. Archives of physical medicine and rehabilitation, 2014, Volume: 95, Issue:4 Topics: Adult; Baclofen; Clonidine; Cross-Over Studies; Double-Blind Method; Electromyography; Humans; Isometric Contraction; Lower Extremity; Male; Middle Aged; Muscle Relaxants, Central; Muscle Strength; Pilot Projects; Reflex, Stretch; Spinal Cord Injuries; Torque	2014
Influence of Previous Failed Antispasticity Therapy on the Efficacy and Tolerability of THC:CBD Oromucosal Spray for Multiple Sclerosis Spasticity. European neurology, 2016, Volume: 75, Issue:5-6 Topics: Adult; Baclofen; Cannabidiol; Clonidine; Dronabinol; Drug Combinations; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Parasympatholytics; Plant Extracts	2016
Effect of Intrathecal Baclofen on Pain and Quality of Life in Poststroke Spasticity. Stroke, 2018, Volume: 49, Issue:9 Topics: Administration, Oral; Aged; Baclofen; Benzodiazepines; Clonidine; Dantrolene; Female; Humans; Infusions, Spinal; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Pain; Pain Measurement; Patient Satisfaction; Physical Therapy Modalities; Quality of Life; Severity of Illness Index; Stroke; Stroke Rehabilitation; Treatment Outcome	2018
A Randomized, Placebo-Controlled Trial of Ibuprofen Plus Metaxalone, Tizanidine, or Baclofen for Acute Low Back Pain. Annals of emergency medicine, 2019, Volume: 74, Issue:4 Topics: Acute Pain; Adult; Analgesics, Non-Narcotic; Baclofen; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Ibuprofen; Low Back Pain; Male; Muscle Relaxants, Central; Oxazolidinones; Treatment Outcome	2019

Other Studies

29 other study(ies) available for baclofen and tizanidine

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The effect of centrally acting myorelaxants on NMDA receptor-mediated synaptic transmission in the immature rat spinal cord in vitro. British journal of pharmacology, 1992, Volume: 107, Issue:2 Topics: Animals; Baclofen; Clonidine; Diazepam; In Vitro Techniques; Muscle Relaxants, Central; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Tetrodotoxin	1992
Flexor reflex for assessment of common interneurone activity in spasticity. Electromyography and clinical neurophysiology, 1992, Volume: 32, Issue:12 Topics: Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Cerebrovascular Disorders; Clonidine; Electroacupuncture; Electromyography; Female; Hemiplegia; Humans; Interneurons; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Reaction Time; Reflex	1992
[The effect of muscle relaxants on the function of the vestibulo-ocular reflex arc]. Ceskoslovenska neurologie a neurochirurgie, 1990, Volume: 53, Issue:2 Topics: Adult; Baclofen; Clonidine; Female; Humans; Male; Muscle Relaxants, Central; Reflex, Vestibulo-Ocular	1990
Tizanidine vs. baclofen in the treatment of spasticity in patients with multiple sclerosis. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1989, Volume: 16, Issue:4 Topics: Baclofen; Clonidine; Drug Tolerance; Humans; Multiple Sclerosis; Muscle Spasticity	1989
Myorelaxant effect after intrathecal injection of antispastic drugs in rats. Neuroscience letters, 1989, Feb-13, Volume: 97, Issue:1-2 Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; Female; H-Reflex; Injections, Spinal; Male; Midazolam; Muscle Contraction; Muscle Relaxation; Parasympatholytics; Rats; Rats, Mutant Strains; Reflex, Monosynaptic; Time Factors	1989
Tizanidine versus baclofen in the treatment of spasticity in multiple sclerosis patients. Acta neurologica Scandinavica, 1988, Volume: 77, Issue:3 Topics: Adult; Aged; Baclofen; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Muscles	1988
Electrophysiological analysis of the mode of action of muscle relaxants in spasticity. Annals of neurology, 1985, Volume: 17, Issue:1 Topics: Baclofen; Clonidine; Diazepam; Electrophysiology; Ethanolamines; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity	1985
Selective depression of synaptic transmission of spinal neurones in the cat by a new centrally acting muscle relaxant, 5-chloro-4-(2-imidazolin-2-yl-amino)-2, 1, 3-benzothiodazole (DS103-282). British journal of pharmacology, 1982, Volume: 76, Issue:3 Topics: Amino Acids; Animals; Baclofen; Cats; Clonidine; Female; Male; Muscle Relaxants, Central; Neurons; Reflex; Spinal Cord; Synapses; Synaptic Transmission	1982
The drug treatment of spasticity. International rehabilitation medicine, 1983, Volume: 5, Issue:3 Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Humans; Muscle Spasticity; Parasympatholytics	1983
Selective antinociceptive effects of tizanidine (DS 103-282), a centrally acting muscle relaxant, on dorsal horn neurones in the feline spinal cord. British journal of pharmacology, 1984, Volume: 82, Issue:2 Topics: Amino Acids; Analgesics; Animals; Baclofen; Cats; Clonidine; Electric Stimulation; Female; Injections, Intravenous; Iontophoresis; Male; Muscle Relaxants, Central; Naloxone; Neurons; Norepinephrine; Spinal Cord	1984
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity. Journal of neurology, neurosurgery, and psychiatry, 1980, Volume: 43, Issue:12 Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiplegia; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Paralysis; Placebos	1980
The effects of central myorelaxants on synaptically-evoked primary afferent depolarization in the immature rat spinal cord in vitro. British journal of pharmacology, 1994, Volume: 111, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Agonists; Animals; Baclofen; Clonidine; Diazepam; Electric Stimulation; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Muscle Relaxants, Central; Nerve Fibers; Neurons, Afferent; Rats; Receptors, Adrenergic, alpha-2; Spinal Cord; Synapses	1994
A comparison of the effects of two antispastic drugs, tizanidine and baclofen, on synaptic transmission from muscle spindle afferents to spinal interneurones in cats. Acta physiologica Scandinavica, 1996, Volume: 156, Issue:1 Topics: Afferent Pathways; Animals; Anticonvulsants; Baclofen; Cats; Clonidine; Dose-Response Relationship, Drug; Interneurons; Muscle Spindles; Synaptic Transmission; Time Factors	1996
[Current data on bipolar disorders, epilepsy and spasticity. 4. Neuro-Forum, Dresden]. Fortschritte der Neurologie-Psychiatrie, 1999, Volume: 67, Issue:5 Suppl Ak Topics: Baclofen; Bipolar Disorder; Clonidine; Epilepsy; Female; Humans; Male; Muscle Relaxants, Central; Muscle Spasticity; Spasm	1999
[Current data on bipolar disorders, epilepsy and spasm. 4th Neuro-Forum, Dresden]. Psychiatrische Praxis, 1999, Volume: 26, Issue:3 Suppl Topics: Baclofen; Benzodiazepines; Bipolar Disorder; Clonidine; Epilepsy; Humans; Muscle Relaxants, Central; Paraplegia	1999
[Pharmacology of spasticity. Does therapy remain in deep sleep?]. Der Nervenarzt, 2000, Volume: 71, Issue:12 Topics: Animals; Baclofen; Botulinum Toxins, Type A; Clonidine; Drug Industry; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Receptors, Adrenergic, alpha-2; Receptors, GABA-B; Research	2000
Treatment of spasticity. Spinal cord, 2002, Volume: 40, Issue:6 Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Spasticity; Paralysis; Rhizotomy	2002
Involuntary jerking of lower half of the body (spinal myoclonus). The Journal of the Association of Physicians of India, 2005, Volume: 53 Topics: Baclofen; Clonazepam; Clonidine; Diagnosis, Differential; Humans; Lower Extremity; Middle Aged; Myoclonus; Spinal Cord; Spinal Cord Diseases	2005
Drug treatments for spasticity. Annals of physical and rehabilitation medicine, 2009, Volume: 52, Issue:10 Topics: Administration, Oral; Adult; Alcohols; Algorithms; Anti-Dyskinesia Agents; Baclofen; Botulinum Toxins; Child; Clonidine; Decision Trees; Humans; Injections, Intramuscular; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Patient Selection; Phenol; Safety; Sclerosing Solutions; Treatment Outcome	2009
Adherence associated with oral medications in the treatment of spasticity. PM & R : the journal of injury, function, and rehabilitation, 2013, Volume: 5, Issue:9 Topics: Administration, Oral; Adult; Baclofen; Clonidine; Dantrolene; Female; Humans; Male; Medication Adherence; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Retrospective Studies; Young Adult	2013
[Comparative effectiveness of different muscle relaxants in the rehabilitation of post-stroke patients with spasticity]. Ideggyogyaszati szemle, 2013, Nov-30, Volume: 66, Issue:11-12 Topics: Aged; Baclofen; Clonidine; Comparative Effectiveness Research; Dantrolene; Female; Humans; Male; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Recovery of Function; Self Report; Stroke; Stroke Rehabilitation; Tolperisone; Treatment Outcome; Walking	2013
Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity. Journal of child neurology, 2016, Volume: 31, Issue:2 Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, Preschool; Clonidine; Drug Therapy, Combination; Equinus Deformity; Female; Follow-Up Studies; Humans; Male; Muscle Spasticity; Neuromuscular Agents; Retrospective Studies; Severity of Illness Index; Treatment Outcome	2016
Early outcomes after intrathecal baclofen therapy in ambulatory patients with multiple sclerosis. Journal of neurosurgery, 2018, Volume: 129, Issue:4 Topics: Administration, Oral; Aged; Ambulatory Care; Baclofen; Clonidine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; Multiple Sclerosis; Muscle Spasticity; Outcome Assessment, Health Care; Pain Measurement; Retrospective Studies; Walking	2018
Trauma-induced adiposis dolorosa (Dercum's disease). BMJ case reports, 2018, Mar-28, Volume: 2018 Topics: Accidents, Traffic; Adipose Tissue; Adiposis Dolorosa; Adult; Amitriptyline; Analgesics, Non-Narcotic; Angiomyolipoma; Baclofen; Chronic Pain; Clonidine; Diagnosis, Differential; Humans; Ibuprofen; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed; Upper Extremity	2018
Italian consensus on treatment of spasticity in multiple sclerosis. European journal of neurology, 2020, Volume: 27, Issue:3 Topics: Baclofen; Botulinum Toxins; Clonidine; Consensus; Disease Management; Gabapentin; Humans; Injections, Intramuscular; Italy; Multiple Sclerosis; Muscle Spasticity; Quality of Life; Transcutaneous Electric Nerve Stimulation	2020
Safety of baclofen versus tizanidine for older adults with musculoskeletal pain. Journal of the American Geriatrics Society, 2023, Volume: 71, Issue:8 Topics: Aged; Baclofen; Delirium; Female; Humans; Male; Muscle Relaxants, Central; Muscle Spasticity; Musculoskeletal Pain; Retrospective Studies	2023