baclofen has been researched along with lesogaberan in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alstermark, C; Amin, K; Dinn, SR; Elebring, T; Fitzpatrick, K; Fjellström, O; Geiss, WB; Gottfries, J; Guzzo, PR; Harding, JP; Holmén, A; Kothare, M; Lehmann, A; Mattsson, JP; Nilsson, K; Sundén, G; Swanson, M; von Unge, S; Woo, AM; Wyle, MJ; Zheng, X | 1 |
| Antonsson, M; Blackshaw, LA; Brändén, L; Bräuner-Osborne, H; Christiansen, B; Dent, J; Elebring, T; Holmberg, AA; Jacobson, BM; Jensen, J; Lehmann, A; Mattsson, JP; Nilsson, K; Oja, SS; Page, AJ; Saransaari, P; von Unge, S | 1 |
| Brändén, L; Fredriksson, A; Harring, E; Jensen, J; Lehmann, A | 1 |
| Adler, J; Boeckxstaens, GE; Lei, A; Ruth, M; Rydholm, H | 1 |
| Holloway, RH; Kuo, P | 1 |
| Storr, MA | 1 |
| Boeckxstaens, GE; Denison, H; Jensen, JM; Lehmann, A; Ruth, M | 1 |
| Benninga, MA; Smout, AJ; van der Pol, R | 1 |
| Ang, D; De Santis, A; Pauwels, A; Scarpellini, E; Tack, J; Vanuytsel, T | 1 |
3 review(s) available for baclofen and lesogaberan
| Article | Year |
|---|---|
Translational gastrointestinal pharmacology in the 21st century: 'the lesogaberan story'.
Topics: Animals; Baclofen; Dogs; Drug Resistance; Esophageal Sphincter, Lower; GABA-B Receptor Agonists; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Muscle Relaxation; Neuromuscular Agents; Phosphinic Acids; Propylamines; Species Specificity; Translational Research, Biomedical | 2011 |
Emerging therapies for GERD.
Topics: Baclofen; GABA-B Receptor Agonists; Gastroesophageal Reflux; Humans; Phosphinic Acids; Propylamines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2011 |
Management of refractory typical GERD symptoms.
Topics: Alginates; Algorithms; Antacids; Baclofen; Chronic Disease; Esophagoscopy; Gastroesophageal Reflux; Gastrointestinal Agents; Gastroscopy; Humans; Isoxazoles; Muscle Relaxants, Central; Neurotransmitter Agents; Phosphinic Acids; Propylamines; Triazoles | 2016 |
1 trial(s) available for baclofen and lesogaberan
| Article | Year |
|---|---|
Effect of lesogaberan, a novel GABA(B)-receptor agonist, on transient lower oesophageal sphincter relaxations in male subjects.
Topics: Adolescent; Adult; Baclofen; Cross-Over Studies; Esophageal Sphincter, Lower; GABA Agonists; Gastroesophageal Reflux; Humans; Male; Manometry; Middle Aged; Muscle Relaxation; Phosphinic Acids; Propylamines; Young Adult | 2010 |
5 other study(ies) available for baclofen and lesogaberan
| Article | Year |
|---|---|
Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.
Topics: Animals; Dose-Response Relationship, Drug; GABA Agonists; GABA-B Receptor Agonists; Gastroesophageal Reflux; Humans; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Fast Atom Bombardment | 2008 |
(R)-(3-amino-2-fluoropropyl) phosphinic acid (AZD3355), a novel GABAB receptor agonist, inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action.
Topics: Animals; Autoradiography; Baclofen; Binding, Competitive; Calcium; Dogs; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Female; Ferrets; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA-B Receptor Agonists; Humans; Hypothermia; In Vitro Techniques; Membrane Potentials; Mice; Muscle Relaxation; Peripheral Nerves; Phosphinic Acids; Propylamines; Protein Binding; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Vagus Nerve | 2009 |
The novel, peripherally restricted GABAB receptor agonist lesogaberan (AZD3355) inhibits acid reflux and reduces esophageal acid exposure as measured with 24-h pHmetry in dogs.
Topics: Animals; Baclofen; Dogs; Esophagus; Female; GABA Agonists; GABA-B Receptor Agonists; Gastric Acid; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Male; Manometry; Phosphinic Acids; Pilot Projects; Propylamines; Receptors, GABA-B; Time Factors | 2010 |
Beyond acid suppression: new pharmacologic approaches for treatment of GERD.
Topics: Animals; Baclofen; Cannabinoid Receptor Agonists; Dogs; Dronabinol; Erythromycin; GABA Agonists; GABA-B Receptor Agonists; Gastroesophageal Reflux; Gastrointestinal Agents; Humans; Phosphinic Acids; Propylamines; Proton Pump Inhibitors; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2010 |
What is nonacid reflux disease?
Topics: Baclofen; Esophageal Sphincter, Lower; Gastroesophageal Reflux; Humans; Phosphinic Acids; Propylamines; Proton Pump Inhibitors; Receptors, GABA-A | 2011 |