baclofen and ketamine

baclofen has been researched along with ketamine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's5 (20.00)18.2507
2000's5 (20.00)29.6817
2010's14 (56.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Henry, JL; Hong, Y1
Bansinath, M; Ramabadran, K; Shukla, VK; Turndorf, H1
Beal, MF; Ferrante, RJ; Kowall, NW; Martin, JB; Swartz, KJ1
Stringer, JL1
Bousquet, P; Chapleau, D; Crambes, A; Feldman, J; Monassier, L; Roegel, JC1
Amabeoku, GJ1
Akizuki, A; Shimoyama, M; Shimoyama, N; Takahashi, H1
Baker, LE; Poling, A; Pynnonen, DM; Searcy, GD1
France, CP; Koek, W1
Barton, D; Grothey, A; Kottschade, L; Loprinzi, C; Wolf, S1
Delhaas, EM; Marinus, J; Munts, AG; van Hilten, JJ; Voormolen, JH1
Barton, DL; Bearden, JD; Christensen, B; Green, NB; Hoff, KL; Kugler, JW; Lanier, KS; Loprinzi, CL; Mattar, BI; Qin, R; Reddy, PS; Riepl, M; Rowland, KM; Wos, EJ1
Ando, Y; Hojo, M; Kanaide, M; Shiraishi, S; Sudo, Y; Sumikawa, K; Takada, M; Uezono, Y1
Canning, BJ; Hilton, ECY; Saulsberry, L; Smith, JA1
Hama, A; Sagen, J1
Bak, K; Bleeker, J; Cavaletti, G; Chauhan, C; Dworkin, RH; Gavin, P; Hershman, DL; Lacchetti, C; Lavino, A; Lavoie Smith, EM; Loprinzi, CL; Lustberg, MB; Paice, J; Schneider, B; Smith, ML; Smith, T; Terstriep, S; Wagner-Johnston, N1
Khanegheini, A; Nasehi, M; Zarrindast, MR1
Banov, D; Bassani, AS1
Akbarabadi, A; Bakhtazad, A; Farahmandfar, M; Zarrindast, MR1
Mohs, AJ; Peace, MR; Poklis, A; Poklis, JL; Wolf, CE1
Keppel Hesselink, JM; Kopsky, DJ1
Krevolin, LE; Shenoda, BB; Sherman, M1

Reviews

4 review(s) available for baclofen and ketamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Palliative medicine for advanced gynecological malignancy].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 10

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Baclofen; Bone Neoplasms; Drug Therapy, Combination; Female; GABA Agonists; Genital Neoplasms, Female; Humans; Ketamine; Morphine; Muscle Neoplasms; Neoplasm Invasiveness; Nerve Block; Oxycodone; Pain, Intractable; Palliative Care; Peritonitis; Receptors, N-Methyl-D-Aspartate

2004
Chemotherapy-induced peripheral neuropathy: prevention and treatment strategies.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:11

    Topics: Acetylcarnitine; Acetylcysteine; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Calcium; Glutamine; Humans; Infusions, Intravenous; Ketamine; Magnesium; Naphthalenes; Nootropic Agents; Paclitaxel; Peripheral Nervous System Diseases; Pyridines; Randomized Controlled Trials as Topic; Vitamin E

2008
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014, Jun-20, Volume: 32, Issue:18

    Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States

2014

Trials

1 trial(s) available for baclofen and ketamine

ArticleYear
A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2011, Volume: 19, Issue:6

    Topics: Administration, Cutaneous; Adrenergic Uptake Inhibitors; Aged; Amitriptyline; Antineoplastic Agents; Baclofen; Double-Blind Method; Drug Combinations; Excitatory Amino Acid Antagonists; Female; GABA-B Receptor Agonists; Gels; Humans; Ketamine; Lecithins; Male; Middle Aged; Peripheral Nervous System Diseases; Poloxamer; Treatment Outcome

2011

Other Studies

20 other study(ies) available for baclofen and ketamine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
NMDA receptor antagonists block cardiovascular responses to intrathecal administration of D-baclofen in the rat.
    European journal of pharmacology, 1992, Jun-05, Volume: 216, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Blood Pressure; Injections, Intravenous; Injections, Spinal; Ketamine; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thoracic Vertebrae

1992
Intracerebroventricular administration of kappa-agonists induces convulsions in mice.
    Brain research bulletin, 1991, Volume: 27, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Baclofen; Benzeneacetamides; Benzomorphans; Cerebral Ventricles; Convulsants; Dizocilpine Maleate; Injections, Intraventricular; Ketamine; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Stereoisomerism; Thiophenes

1991
Systemic approaches to modifying quinolinic acid striatal lesions in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:10

    Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine

1988
Alterations in both excitation and inhibition occur before the onset of seizure activity in the hippocampus.
    Epilepsy research, 1993, Volume: 16, Issue:2

    Topics: Animals; Baclofen; Bicuculline; Diazepam; Electric Stimulation; Evoked Potentials; Hippocampus; Ketamine; Kindling, Neurologic; Limbic System; Male; Neurons; Phenobarbital; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Seizures; Stereotaxic Techniques; Synapses

1993
GABAergic and glutaminergic modulation of centrally evoked arrhythmias in rats.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Baclofen; Brain; Cardiovascular System; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Glutamine; Injections, Intravenous; Injections, Intraventricular; Ketamine; Kynurenic Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Synaptic Transmission

1996
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
    General pharmacology, 1999, Volume: 32, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline

1999
Differentiating the discriminative stimulus effects of gamma-hydroxybutyrate and ethanol in a three-choice drug discrimination procedure in rats.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:4

    Topics: 4-Butyrolactone; Animals; Baclofen; Benzocycloheptenes; Butylene Glycols; Discrimination, Psychological; Ethanol; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Ketamine; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Sodium Oxybate

2008
Cataleptic effects of gamma-hydroxybutyrate (GHB) and baclofen in mice: mediation by GABA(B) receptors, but differential enhancement by N-methyl-d-aspartate (NMDA) receptor antagonists.
    Psychopharmacology, 2008, Volume: 199, Issue:2

    Topics: Anesthetics, Intravenous; Animals; Area Under Curve; Ataxia; Baclofen; Catalepsy; Data Interpretation, Statistical; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice; Mice, Inbred C57BL; Muscle Relaxants, Central; Phencyclidine; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Sodium Oxybate

2008
Postdural puncture headache in complex regional pain syndrome: a retrospective observational study.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:8

    Topics: Adolescent; Adult; Anesthetics, Dissociative; Baclofen; Blood Patch, Epidural; Causality; Cerebrospinal Fluid Pressure; Complex Regional Pain Syndromes; Dura Mater; Dystonia; Female; GABA Agonists; Headache; Humans; Incidence; Injections, Spinal; Intracranial Hypotension; Ketamine; Male; Middle Aged; Retrospective Studies; Spinal Puncture; Treatment Outcome; Young Adult

2009
S(+)-ketamine suppresses desensitization of γ-aminobutyric acid type B receptor-mediated signaling by inhibition of the interaction of γ-aminobutyric acid type B receptors with G protein-coupled receptor kinase 4 or 5.
    Anesthesiology, 2011, Volume: 114, Issue:2

    Topics: Analgesics; Animals; Baclofen; Blotting, Western; Cells, Cultured; Cricetinae; Drug Interactions; Drug Tolerance; Electrophysiological Phenomena; Fluorescence Resonance Energy Transfer; G Protein-Coupled Inwardly-Rectifying Potassium Channels; G-Protein-Coupled Receptor Kinases; GABA-B Receptor Agonists; Ketamine; Kidney; Mice; Microscopy, Confocal; Rats; Receptors, GABA-B; Signal Transduction; Xenopus

2011
Antitussive effects of memantine in guinea pigs.
    Chest, 2012, Volume: 141, Issue:4

    Topics: Animals; Antitussive Agents; Baclofen; Bradykinin; Citric Acid; Cough; Dextromethorphan; Guinea Pigs; Ketamine; Male; Mecamylamine; Memantine; N-Methylaspartate; Serotonin

2012
Combinations of intrathecal gamma-amino-butyrate receptor agonists and N-methyl-d-aspartate receptor antagonists in rats with neuropathic spinal cord injury pain.
    European journal of pharmacology, 2012, May-15, Volume: 683, Issue:1-3

    Topics: Analgesia, Epidural; Animals; Baclofen; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; GABA-A Receptor Agonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Ketamine; Lumbar Vertebrae; Male; Muscimol; Neuralgia; Pain Threshold; Proteins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries

2012
The modulatory effect of CA1 GABAb receptors on ketamine-induced spatial and non-spatial novelty detection deficits with respect to Ca(2+).
    Neuroscience, 2015, Oct-01, Volume: 305

    Topics: Analysis of Variance; Animals; Baclofen; CA1 Region, Hippocampal; Calcium; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; GABA Antagonists; Imidazoles; Ketamine; Male; Memory Disorders; Mice; Receptors, GABA-A; Signal Detection, Psychological; Spatial Processing

2015
Evaluation of the Percutaneous Absorption of Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen, in Compounded Transdermal Pain Formulations, Using the Franz Finite Dose Model.
    Pain medicine (Malden, Mass.), 2016, Volume: 17, Issue:2

    Topics: Administration, Cutaneous; Aged; Amines; Baclofen; Clonidine; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Organ Culture Techniques; Pain; Skin Absorption

2016
Recovery from ketamine-induced amnesia by blockade of GABA-A receptor in the medial prefrontal cortex of mice.
    Neuroscience, 2017, 03-06, Volume: 344

    Topics: Amnesia; Animals; Baclofen; Bicuculline; Catheters, Indwelling; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; Ketamine; Male; Memory; Mice; Muscimol; Neuropsychological Tests; Prefrontal Cortex; Receptors, GABA-A; Time Factors

2017
Identification of Drugs in Parenteral Pharmaceutical Preparations from a Quality Assurance and a Diversion Program by Direct Analysis in Real-Time AccuTOFTM-Mass Spectrometry (DART-MS).
    Journal of analytical toxicology, 2016, Volume: 40, Issue:8

    Topics: Amides; Analgesics; Anesthetics; Baclofen; Bupivacaine; Caffeine; Chromatography, High Pressure Liquid; Clonidine; Dexamethasone; Ephedrine; Fentanyl; Heparin; Hydromorphone; Ketamine; Mass Spectrometry; Methadone; Midazolam; Morphine; Oxytocin; Parenteral Nutrition Solutions; Phenylephrine; Ropivacaine; Succinylcholine

2016
Phenytoin in topical formulations augments pain reduction of other topically applied analgesics in the treatment of trigeminal neuralgia.
    Journal of clinical anesthesia, 2017, Volume: 38

    Topics: Administration, Cutaneous; Aged; Analgesics; Baclofen; Drug Synergism; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Nociceptors; Pain Management; Phenytoin; Skin Cream; Time Factors; Touch; Trigeminal Neuralgia

2017
Syndrome of Inappropriate Antidiuretic Hormone Release During Ketamine Infusion in Complex Regional Syndrome Patient Receiving Intrathecal Baclofen: A Case Report.
    A&A practice, 2019, Nov-15, Volume: 13, Issue:10

    Topics: Baclofen; Complex Regional Pain Syndromes; Female; Humans; Inappropriate ADH Syndrome; Injections, Intraventricular; Injections, Spinal; Ketamine; Middle Aged; Sodium Potassium Chloride Symporter Inhibitors; Treatment Outcome

2019