baclofen and indomethacin

baclofen has been researched along with indomethacin in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's6 (26.09)18.2507
2000's5 (21.74)29.6817
2010's5 (21.74)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Deguchi, T; Hosoya, K; Kang, YS; Mori, S; Ohtsuki, S; Takanaga, H; Terasaki, T1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Miñano, FJ; Sancibrian, M; Serrano, JS1
Kauffman, G; Saperas, E; Taché, Y1
Cass, WA; Dunwiddie, TV; Fitzpatrick, FA; Taylor, M; Zahniser, NR1
Minami, M; Niida, H; Okabe, S; Takeuchi, K1
Magistretti, PJ; Schaad, NC; Schorderet, M1
Maggi, CA; Meli, A; Santicioli, P1
Foong, FW; Satoh, M1
Sears, M; Soloway, MR; Stjernschantz, J1
Couture, R; Cuello, AC1
Amico-Roxas, M; Caruso, A; Cutuli, VM; de Bernardis, E; Lucenti, A; Villari, L1
Olianas, MC; Onali, P1
Deboer, SR; Guterman, EL; Manesh, R; Platt, L; Probasco, JC; Shenderov, K; Sperati, CJ1

Reviews

1 review(s) available for baclofen and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

22 other study(ies) available for baclofen and indomethacin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:4

    Topics: Animals; Blood-Brain Barrier; Cimetidine; Convulsants; Endothelium, Vascular; Enzyme Inhibitors; Homovanillic Acid; Indican; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Penicillin G; Rats; Rats, Wistar; Transfection; Tritium; Xenopus laevis

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Opioid and prostaglandin mechanisms involved in the effects of GABAergic drugs on body temperature.
    General pharmacology, 1991, Volume: 22, Issue:2

    Topics: Animals; Baclofen; Bicuculline; Body Temperature; Dose-Response Relationship, Drug; Endorphins; gamma-Aminobutyric Acid; Indomethacin; Injections, Intraperitoneal; Muscimol; Naloxone; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, GABA-A

1991
Role of central prostaglandin E2 in the regulation of gastric acid secretion in the rat.
    European journal of pharmacology, 1991, Dec-10, Volume: 209, Issue:1-2

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Baclofen; Brain; Cisterna Magna; Dinoprostone; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Indomethacin; Infusions, Intravenous; Injections; Male; Prostaglandins; Rats; Rats, Inbred Strains; Vagus Nerve

1991
Arachidonic acid metabolites do not mediate modulation of neurotransmitter release by adenosine in rat hippocampus or striatum.
    Brain research, 1990, Sep-10, Volume: 527, Issue:1

    Topics: Acetophenones; Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Baclofen; Carbachol; Corpus Striatum; Evoked Potentials; Hippocampus; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Neurotransmitter Agents; Phospholipases; Rats; Rats, Inbred Strains; Second Messenger Systems; Thiazoles

1990
Determination of bicarbonate output using pH deflection in the rat duodenum: influences of prostaglandins and cholinergic agents.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:2

    Topics: Alprostadil; Animals; Azetidines; Baclofen; Bicarbonates; Dinoprostone; Dipeptides; Duodenum; Epoprostenol; Hydrogen-Ion Concentration; Indomethacin; Male; Parasympathomimetics; Prostaglandins; Rats; Rats, Inbred Strains

1990
Accumulation of cyclic AMP elicited by vasoactive intestinal peptide is potentiated by noradrenaline, histamine, adenosine, baclofen, phorbol esters, and ouabain in mouse cerebral cortical slices: studies on the role of arachidonic acid metabolites and pr
    Journal of neurochemistry, 1989, Volume: 53, Issue:6

    Topics: Adenosine; Animals; Arachidonic Acids; Baclofen; Caffeic Acids; Cerebral Cortex; Cyclic AMP; Drug Synergism; Histamine; In Vitro Techniques; Indomethacin; Kinetics; Male; Mice; Norepinephrine; Ouabain; Phorbol 12,13-Dibutyrate; Prostaglandins; Protein Kinase C; Vasoactive Intestinal Peptide

1989
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:2

    Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder

1985
Analgesic potencies of non-narcotic, narcotic and anesthetic drugs as determined by the bradykinin-induced biting-like responses in rats.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Anesthetics; Animals; Baclofen; Bradykinin; Chloralose; Dose-Response Relationship, Drug; Indomethacin; Lidocaine; Male; Morphine; Nociceptors; Rats; Rats, Inbred Strains

1983
The miotic effect of substance P on the isolated rabbit iris.
    Investigative ophthalmology & visual science, 1981, Volume: 20, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Baclofen; Dose-Response Relationship, Drug; Egtazic Acid; Indomethacin; Iris; Male; Miotics; Rabbits; Substance P

1981
Studies on the trigeminal antidromic vasodilatation and plasma extravasation in the rat.
    The Journal of physiology, 1984, Volume: 346

    Topics: Animals; Baclofen; Capillary Permeability; Cimetidine; Evoked Potentials; Female; Indomethacin; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Substance P; Sympatholytics; Trigeminal Nerve; Vasodilation

1984
Effects of GABAergic drugs on ethanol-induced gastric lesions.
    Journal of physiology, Paris, 1993, Volume: 87, Issue:6

    Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Hemorrhage; Indomethacin; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Valproic Acid

1993
GABA(B) receptor-mediated stimulation of adenylyl cyclase activity in membranes of rat olfactory bulb.
    British journal of pharmacology, 1999, Volume: 126, Issue:3

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Baclofen; Calcium; Calmodulin; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Indomethacin; Injections, Intraventricular; Male; Membranes; Neuropeptides; Neuroprotective Agents; Olfactory Bulb; Organophosphorus Compounds; Pertussis Toxin; Phosphinic Acids; Phospholipases A; Phospholipids; Pituitary Adenylate Cyclase-Activating Polypeptide; Propanolamines; Propylamines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Transducin; Virulence Factors, Bordetella

1999
Egad!
    Journal of hospital medicine, 2019, Volume: 14, Issue:3

    Topics: Aged; Baclofen; Colchicine; Diagnosis, Differential; Female; Gout; Hallux; Hospitalization; Humans; Indomethacin; Pain; Patient Readmission; Spasm; Thymoma

2019