baclofen and guanosine triphosphate

baclofen has been researched along with guanosine triphosphate in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's7 (29.17)18.2507
2000's5 (20.83)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dolphin, AC; Sweeney, MI1
Dolphin, AC; Scott, RH1
Andrade, R; Malenka, RC; Nicoll, RA1
Lacey, MG; Mercuri, NB; North, RA1
Dolphin, AC; McGuirk, SM; Scott, RH2
al-Dahan, MI; Thalmann, RH1
Goh, JW; Pennefather, PS1
Lukasiewicz, P; Maguire, G; Maple, B; Werblin, F1
Singh, R; Ticku, MK1
Aghajanian, GK; Innis, RB; Nestler, EJ1
Thalmann, RH1
Bowery, NG; Hill, DR; Hudson, AL1
Andrade, R1
Boehm, S; Freissmuth, M; Hohenegger, M; Nanoff, C; Schütz, W1
Cullen, G; Dolphin, AC; Fazeli, MS; Huston, E; Pearson, H; Sweeney, MI1
Snead, OC1
Alger, BE; Lenz, RA; Pitler, TA1
Koyama, T; Nishi, N; Odagaki, Y; Ozawa, H; Riederer, P; Saito, T; Takahata, N1
Koyama, T; Odagaki, Y1
Neher, E; Sakaba, T1
Cens, T; Charnet, P; Gouin-Charnet, A; Rousset, M; Scamps, F1
Collingridge, GL; Isaac, JT; Lauri, SE; Maingret, F; Mulle, C; Segerstråle, M; Taira, T; Vesikansa, A1
Fujita, T; Oka, M; Wada, M; Wu, Q; Yamamoto, A1

Other Studies

24 other study(ies) available for baclofen and guanosine triphosphate

ArticleYear
1,4-Dihydropyridines modulate GTP hydrolysis by Go in neuronal membranes.
    FEBS letters, 1992, Sep-21, Volume: 310, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Calcium Channels; Cell Membrane; Cerebral Cortex; Dihydropyridines; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Immune Sera; Male; Neurons; Rats; Rats, Inbred Strains

1992
Regulation of calcium currents by a GTP analogue: potentiation of (-)-baclofen-mediated inhibition.
    Neuroscience letters, 1986, Aug-15, Volume: 69, Issue:1

    Topics: Animals; Baclofen; Calcium; Cells, Cultured; Drug Synergism; Ganglia, Spinal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channels; Membrane Potentials; Rats; Thionucleotides

1986
A G protein couples serotonin and GABAB receptors to the same channels in hippocampus.
    Science (New York, N.Y.), 1986, Dec-05, Volume: 234, Issue:4781

    Topics: Animals; Baclofen; Calcium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Hippocampus; Ion Channels; Phorbol 12,13-Dibutyrate; Phorbol Esters; Potassium; Rats; Receptors, GABA-A; Receptors, Serotonin; Serotonin; Spiperone; Thionucleotides

1986
On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones.
    The Journal of physiology, 1988, Volume: 401

    Topics: Action Potentials; Animals; Baclofen; Dopamine; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Ion Channels; Male; Muscimol; Neurons; Potassium; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, GABA-A; Substantia Nigra; Thionucleotides; Time Factors

1988
Modulation of divalent cation-activated chloride ion currents.
    British journal of pharmacology, 1988, Volume: 94, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Baclofen; Barium; Caffeine; Calcium Channels; Chlorides; Ganglia, Spinal; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Ion Channels; Neurons; Rats; Thionucleotides

1988
Effect of guanosine 5'-O-(3-thiotriphosphate) and calcium on gamma-aminobutyric acidB binding as a function of postnatal development.
    Journal of neurochemistry, 1989, Volume: 52, Issue:1

    Topics: Animals; Baclofen; Brain; Calcium; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Mathematics; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thionucleotides

1989
An investigation into the mechanisms of inhibition of calcium channel currents in cultured sensory neurones of the rat by guanine nucleotide analogues and (-)-baclofen.
    British journal of pharmacology, 1989, Volume: 97, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Baclofen; Calcium Channels; Cells, Cultured; Cholera Toxin; Colforsin; Culture Techniques; Electrophysiology; Enzyme Activation; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Neurons, Afferent; Protein Kinase C; Rats; Thionucleotides; Type C Phospholipases

1989
A pertussis toxin-sensitive G protein in hippocampal long-term potentiation.
    Science (New York, N.Y.), 1989, May-26, Volume: 244, Issue:4907

    Topics: Animals; Baclofen; Electric Conductivity; Enzyme Activation; Evoked Potentials; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hippocampus; Injections, Intraventricular; Male; Membrane Potentials; Neurons; Pertussis Toxin; Protein Kinase C; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Thionucleotides; Virulence Factors, Bordetella

1989
Gamma-aminobutyrate type B receptor modulation of L-type calcium channel current at bipolar cell terminals in the retina of the tiger salamander.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:24

    Topics: Animals; Axons; Baclofen; Calcium Channels; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Receptors, GABA-A; Retina; Retinal Ganglion Cells; Synapses; Thionucleotides; Urodela

1989
Comparison of [3H]baclofen binding to GABAB receptors in spontaneously hypertensive and normotensive rats.
    Brain research, 1985, Dec-09, Volume: 358, Issue:1-2

    Topics: Adenylyl Cyclases; Animals; Baclofen; Brain; Cerebellum; Guanosine Triphosphate; Hippocampus; Hypertension; Male; Medulla Oblongata; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA-A

1985
Evidence for G protein mediation of serotonin- and GABAB-induced hyperpolarization of rat dorsal raphe neurons.
    Brain research, 1988, Aug-30, Volume: 459, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Baclofen; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Male; Membrane Potentials; Pertussis Toxin; Raphe Nuclei; Rats; Serotonin; Thionucleotides; Virulence Factors, Bordetella

1988
Evidence that guanosine triphosphate (GTP)-binding proteins control a synaptic response in brain: effect of pertussis toxin and GTP gamma S on the late inhibitory postsynaptic potential of hippocampal CA3 neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12

    Topics: Adenylate Cyclase Toxin; Animals; Baclofen; Brain; Electric Conductivity; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Isoxazoles; Membrane Potentials; Neural Inhibition; Neurons; Pertussis Toxin; Rats; Synapses; Thionucleotides; Time Factors; Virulence Factors, Bordetella

1988
Inhibition of GABAB receptor binding by guanyl nucleotides.
    Journal of neurochemistry, 1984, Volume: 42, Issue:3

    Topics: Animals; Baclofen; Brain; Calcium Chloride; gamma-Aminobutyric Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Kinetics; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes

1984
Infusion of guanine nucleotides through recording electrodes for studies on G-protein regulation of ion currents and channels.
    Methods in enzymology, 1994, Volume: 238

    Topics: Animals; Baclofen; Carbachol; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Ion Channels; Membrane Potentials; Microelectrodes; Pyramidal Cells; Rats; Serotonin; Thionucleotides

1994
2',3'-Dialdehyde GTP as an irreversible G protein antagonist. Disruption and reconstitution of G protein-mediated signal transduction in cells and cell membranes.
    The Journal of biological chemistry, 1994, Dec-16, Volume: 269, Issue:50

    Topics: Adenylyl Cyclases; Affinity Labels; Animals; Baclofen; Blood Platelets; Calcium Channels; Cell Membrane; Chick Embryo; GTP-Binding Proteins; Guanosine Triphosphate; Humans; In Vitro Techniques; Ion Channel Gating; Neurons; Recombinant Proteins; Signal Transduction

1994
Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons.
    Neuroscience, 1993, Volume: 52, Issue:4

    Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Baclofen; Barium; Binding Sites; Calcium; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic AMP; Dihydropyridines; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamine; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Membrane Potentials; NAD; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella

1993
Relation of the [3H] gamma-hydroxybutyric acid (GHB) binding site to the gamma-aminobutyric acidB (GABAB) receptor in rat brain.
    Biochemical pharmacology, 1996, Oct-25, Volume: 52, Issue:8

    Topics: Animals; Autoradiography; Baclofen; Benzocycloheptenes; Binding Sites; Brain; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guanosine Triphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Seizures; Sodium Oxybate; Stereoisomerism

1996
High intracellular Cl- concentrations depress G-protein-modulated ionic conductances.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Aug-15, Volume: 17, Issue:16

    Topics: Animals; Baclofen; Chlorides; Cortical Spreading Depression; Dose-Response Relationship, Drug; Electric Conductivity; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Membrane Potentials; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Serotonin; Synapses

1997
Measurement of receptor-mediated functional activation of G proteins in postmortem human brain membranes.
    Brain research, 1998, Apr-06, Volume: 789, Issue:1

    Topics: Aged; Aged, 80 and over; Baclofen; Binding, Competitive; Brain; Cadaver; Female; GABA Agonists; gamma-Aminobutyric Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Magnesium Chloride; Male; Membranes; Middle Aged; Receptors, GABA-B

1998
Identification of galpha subtype(s) involved in gamma-aminobutyric acid(B) receptor-mediated high-affinity guanosine triphosphatase activity in rat cerebral cortical membranes.
    Neuroscience letters, 2001, Jan-12, Volume: 297, Issue:2

    Topics: Animals; Antibodies; Baclofen; Blood Proteins; Cell Membrane; Cerebral Cortex; GABA Agonists; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Guanosine Triphosphate; Male; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Signal Transduction

2001
Direct modulation of synaptic vesicle priming by GABA(B) receptor activation at a glutamatergic synapse.
    Nature, 2003, Aug-14, Volume: 424, Issue:6950

    Topics: Animals; Baclofen; Brain Stem; Calcium; Calcium Signaling; Calmodulin; Cyclic AMP; Excitatory Postsynaptic Potentials; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Neurons; Rats; Rats, Wistar; Receptors, GABA-B; Synapses; Synaptic Transmission; Synaptic Vesicles

2003
Ca2+ and phosphatidylinositol 4,5-bisphosphate stabilize a Gbeta gamma-sensitive state of Ca V2 Ca 2+ channels.
    The Journal of biological chemistry, 2004, Apr-09, Volume: 279, Issue:15

    Topics: Androstadienes; Animals; Baclofen; Calcium; Calcium Channels, N-Type; Cell Membrane; Chelating Agents; Cytoskeleton; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Enzyme Inhibitors; Ganglia, Spinal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Membrane Potentials; Mice; Neurons; Oocytes; Phosphatidylinositol 4,5-Diphosphate; Phospholipids; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Time Factors; Wortmannin; Xenopus; Xenopus laevis

2004
Endogenous activation of kainate receptors regulates glutamate release and network activity in the developing hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, May-04, Volume: 25, Issue:18

    Topics: Animals; Animals, Newborn; Aspartic Acid; Baclofen; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Furans; GABA Agonists; GABA Antagonists; Glutamic Acid; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Interneurons; Isoquinolines; Isoxazoles; Membrane Potentials; Mice; Mice, Knockout; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Picrotoxin; Probability; Receptors, Kainic Acid

2005
Functional expression of metabotropic GABAB receptors in primary cultures of astrocytes from rat cerebral cortex.
    Biochemical and biophysical research communications, 2006, Mar-17, Volume: 341, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Astrocytes; Baclofen; Cell Membrane; Cells, Cultured; Cerebral Cortex; Colforsin; Gene Expression Regulation; Guanosine Triphosphate; Rats; Receptors, GABA-B; RNA, Messenger

2006