baclofen has been researched along with gamma-aminobutyric acid in 1126 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 312 (27.71) | 18.7374 |
| 1990's | 448 (39.79) | 18.2507 |
| 2000's | 249 (22.11) | 29.6817 |
| 2010's | 101 (8.97) | 24.3611 |
| 2020's | 16 (1.42) | 2.80 |
| Authors | Studies |
|---|---|
| Berthelot, P; Brunet, C; Debaert, M; Flouquet, N; Luyckx, M; Vaccher, C | 1 |
| Boulanger, T; Brandau, B; Desaulles, E; Durant, F; Evrard, G; Heaulme, M; Mann, A; Wermuth, CG | 1 |
| Enna, SJ; Fung, YK; Patch, RJ; Witiak, DT | 1 |
| Berthelot, P; Debaert, M; Flouquet, N; Luyckx, M; Musadad, A; Vaccher, C | 1 |
| Baumann, PA; Brugger, F; Froestl, W; Gentsch, C; Hall, RG; Jaekel, J; Mickel, SJ; Olpe, HR; Strub, D; von Sprecher, G | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Bora-Tatar, G; Dalkara, S; Dayangaç-Erden, D; Demir, AS; Erdem-Yurter, H; Yelekçi, K | 1 |
| Chester, JA; Colby, DA; Han, C; Hockerman, GH; Jarrard, RE; Jiang, X; Kim, EH; Kirchhoff, AM; Powers, MS; Salvador, TK; Salyer, AE | 1 |
| Bay, T; Bundgaard, C; Clausen, RP; Frølund, B; Kehler, J; Marek, A; Pedersen, MH; Vogensen, SB; Wellendorph, P | 1 |
| Adams, DJ; Cai, F; Dai, Q; Ding, R; Dong, M; Liu, Z; Shen, J; Tae, HS; Wang, S; Xu, N; Yu, S; Zhang, X | 1 |
| Carlsson, VA | 1 |
| Waddington, JL | 3 |
| Johnston, GA | 1 |
| Kerwin, R; Pycock, C | 2 |
| Cross, AJ; Waddington, JL | 2 |
| Henning, M; Persson, B | 2 |
| van den Berg, CJ | 1 |
| Meldrum, BS | 1 |
| Paulson, GW | 1 |
| Fukuda, H; Kudo, Y; Ono, H | 1 |
| Costa, E; Guidotti, A; Naik, SR | 1 |
| Guidotti, A; Kurosawa, A; Naik, SR | 1 |
| Gupta, HK; Roberts, PJ; Shargill, NS | 1 |
| Breese, GR; Mailman, RB; Mueller, RA | 1 |
| Bowery, NG; Doble, A; Hill, DR; Hudson, AL; Shaw, JS; Turnbull, MJ | 1 |
| Cross, AL; Waddington, JL | 1 |
| Dinnendahl, V; Gumulka, SW; Schönhöfer, PS | 1 |
| Biswas, B; Carlsson, A; Lindqvist, M | 1 |
| Tanner, T | 1 |
| Chéramy, A; Glowinski, J; Nieoullon, A | 1 |
| Przewłocka, B; Scheel-Krüger, J; Stala, L | 1 |
| Cross, AJ; Crow, TJ; Waddington, JL | 1 |
| Delini-Stula, A; Vassout, A | 2 |
| Andén, NE; Wachtel, H | 1 |
| Kelly, PH; Moore, KE | 1 |
| Bardakjian, J; Gonnard, P; Rolland, B; Tardy, M | 1 |
| Beubler, E; Lembeck, F | 1 |
| Agnati, L; Fuxe, K; Hökfelt, T; Johansson, O; Ljungdahl, A; Perez de la Mora, M | 1 |
| Duma-Drzewińska, A; Kiwerski, J; Makowski, J | 1 |
| Kääriäinen, I | 1 |
| Carlsson, A; Cott, J; Engel, J; Lindqvist, M | 1 |
| Nistri, A | 1 |
| McCormick, DA | 2 |
| Chen, TF; Doyle, PT; Ferguson, DR | 1 |
| Snodgrass, SR | 1 |
| Bourdelais, AJ; Kalivas, PW | 1 |
| Depaulis, A; Liu, Z; Marescaux, C; Vergnes, M | 1 |
| Cohen, B; Holstein, GR; Martinelli, GP | 1 |
| Berger, TW; Nisenbaum, ES | 1 |
| Ogata, N; Tatebayashi, H | 2 |
| Carbone, S; Moguilevsky, JA; Szwarcfarb, B | 1 |
| DeWitte, P; Kalivas, PW; Klitenick, MA | 1 |
| Kelly, MJ; Loose, MD; Ronnekleiv, OK | 1 |
| Bernardi, G; Calabresi, P; Mercuri, NB; Stefani, A | 1 |
| Nicoll, RA; Solís, JM | 1 |
| Jarolimek, W; Misgeld, U | 2 |
| Brooker, G; Costa, E; De Erausquin, G; Wojcik, WJ | 1 |
| Misgeld, U | 1 |
| Brown, LL; Moshé, SL; Sperber, EF; Tempel, A | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Hamon, M; Legrand, JC; Mauborgne, A; Pohl, M | 1 |
| Moises, HC; Washburn, MS | 1 |
| Amit, Z; Robidoux, J; Smith, BR | 1 |
| Berthelot, P; Debaert, M; Flouquet, N; Kerr, DI; Ong, J; Vaccher, C | 1 |
| Bijak, M; Brunner, H; Misgeld, U | 1 |
| Alkon, DL; Sanchez-Andres, JV; Schreurs, BG | 1 |
| Ebbesson, SO; Erdö, SL; Hofmann, MH; Malz, CR; Meyer, DL | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Hammond, DL; Moy, ML | 1 |
| Avoli, M; Siniscalchi, A | 1 |
| Eguibar, JR; Jiménez, I; Quevedo, J; Rudomin, P | 1 |
| Beani, L; Bianchi, C; Ferraro, L; Tanganelli, S | 2 |
| Berger, TW; Grace, AA; Nisenbaum, ES | 2 |
| Dun, NJ; Wu, SY | 1 |
| Bonanno, G; Raiteri, M | 3 |
| Davidson, K; Gillies, G | 1 |
| Donoso, AO; López, FJ; Negro-Vilar, A | 1 |
| Finch, DM; Mello, LE; Tan, AM | 1 |
| Feldtrauer, JJ; Stöcklin, K; Waldmeier, PC | 1 |
| Callaway, JK; King, RG | 1 |
| Scarth, BA; Shaw, C | 1 |
| Dunwiddie, TV; Lupica, CR; Proctor, WR | 1 |
| Takeuchi, H | 1 |
| Harish, OE; Role, LW | 1 |
| Benoliel, JJ; Bourgoin, S; Cesselin, F; Collin, E; Hamon, M; Mauborgne, A; Pohl, M | 1 |
| Gedye, A | 1 |
| Fernández, A; Ruiz, RM; Serrano, I; Serrano, JS | 1 |
| Hao, JX; Seiger, A; Wiesenfeld-Hallin, Z; Xu, XJ; Yu, YX | 1 |
| Chang, JP; Dubourg, P; Kah, O; Peter, RE; Sloley, BD; Trudeau, VL; Yu, KL | 1 |
| Dutia, MB; Johnston, AR; McQueen, DS | 1 |
| Dutar, P; Jazat, F; Lamour, Y; Potier, B; Rascol, O | 1 |
| Amabeoku, G | 1 |
| Duckles, SP; Li, YJ | 1 |
| Pencheva, N; Radomirov, R; Venkova, K | 2 |
| Slaughter, MM; Stockton, RA | 1 |
| Miñano, FJ; Sancibrian, M; Serrano, JS | 1 |
| Barolet, AW; Morris, ME | 1 |
| Heidelberger, R; Matthews, G | 1 |
| Dreher, J; Eshel, G; Jackson, DM; Ong, J; Wong, LS | 1 |
| Kow, LM; Ogawa, S; Pfaff, DW | 1 |
| Fujita, S; Kusunoki, M; Sakanoue, Y; Shoji, Y; Utsunomiya, J; Yamamura, T; Yanagi, H | 1 |
| Agmo, A; Gutiérrez, M; Guzmán, M; Pruneda, R | 1 |
| Bindokas, VP; Ishida, AT | 1 |
| Alford, S; Grillner, S | 1 |
| Giridhar, J; Isom, GE; Peoples, RW | 1 |
| Howson, W; Lacey, MG; Seabrook, GR | 1 |
| Fodstad, H; Ljunggren, BC | 1 |
| Doroshenko, P; Neher, E | 1 |
| Bianconi, L; Capretti, L; Castelli, A; Cerri, L; Chiodera, P; Coiro, V; Marcato, A; Roberti, G; Volpi, R | 1 |
| Carbone, S; Moguilevsky, JA; Rondina, D; Szwarcfarb, B | 1 |
| Gautam, SK; Kulkarni, SK | 1 |
| Malinowska, B; Molderings, G; Schlicker, E; Schneider, D | 1 |
| Henry, JL; Hong, Y | 1 |
| Lee, MH; Strahlendorf, HK; Strahlendorf, JC | 1 |
| Rothman, SM; Yoon, KW | 1 |
| Bernardi, G; Calabresi, P; De Murtas, M; Mercuri, NB | 2 |
| Osmanović, SS; Shefner, SA | 1 |
| Collewijn, H; Pompeiano, O; van Neerven, J | 1 |
| Iarkov, AV; Kovalev, GI; Vorob'ev, VV | 1 |
| Luhmann, HJ; Prince, DA | 1 |
| Gilbert, CD; Hirsch, JA | 1 |
| Higashi, H; Nishi, S; Tanaka, E | 1 |
| North, RA; Uchimura, N | 1 |
| Higashi, H; Inokuchi, H; Nishi, S; Nose, I | 1 |
| Kamiya, H | 1 |
| Boelen, MK; Chubb, IW; Dowton, M; Morgan, IG; Wellard, J | 1 |
| Asprodini, EK; Rainnie, DG; Shinnick-Gallagher, P | 1 |
| Aceves, J; Arias-Montaño, JA; Martínez-Fong, D | 1 |
| Bonanno, G; Fedele, E; Fontana, G; Gemignani, A; Raiteri, M | 1 |
| Li, J; Smith, SS | 1 |
| Akaike, N; Ikemoto, Y; Kits, KS; Oyama, Y | 1 |
| Lothman, EW; Stringer, JL | 1 |
| Miledi, R; Polenzani, L; Woodward, RM | 1 |
| Jones, AJ; Keen, P; Ray, NJ | 1 |
| Carignani, C; Marchetti, C; Robello, M | 1 |
| Couture, R; De Champlain, J; Hasséssian, H; Prat, A | 1 |
| Ben-Ari, Y; Cherubini, E; Gaiarsa, JL | 1 |
| Martin, DL; Rimvall, K | 1 |
| Drew, CA; Johnston, GA | 1 |
| Caffarra, P; Caffarri, G; Chiodera, P; Coiro, V; Delsignore, R; Marcato, A; Rossi, G; Scaglioni, A; Volpi, R | 1 |
| Krnjević, K; Xu, YZ; Zhang, L | 1 |
| Ekström, P; Meissl, H | 1 |
| Calandra, RS; Campos, MB; Ritta, MN | 1 |
| Greenshaw, AJ; McManus, DJ | 1 |
| Fredow, G; Löscher, W | 1 |
| Cowell, J; Frankfurt, M; Luine, V | 1 |
| Carpenter, DO; Doi, N; Hori, N | 1 |
| Harris, V; Vasko, MR | 1 |
| Goto, Y; Hara, N; Hara, Y | 2 |
| Gallagher, JP; Twery, MJ | 1 |
| Albers, HE; Liou, SY; Shibata, S; Ueki, S | 1 |
| Chung, SH; Gage, PW; Premkumar, LS | 1 |
| Dolphin, AC; Huston, E; Scott, RH | 1 |
| Alberch, J; Arenas, E; Marsal, J | 1 |
| Kotak, VC; Page, CH | 1 |
| Andrioli, GC; Bonanno, G; Raiteri, M; Ruelle, A | 1 |
| Alhaider, AA; Lei, SZ; Wilcox, GL | 1 |
| Cremades, A; Del Rio-Garcia, J | 1 |
| Sandyk, R | 1 |
| Hösli, E; Hösli, L; Redle, S; Rojas, J; Schramek, H | 1 |
| James, MD; Leigh, AJ; Wilson, CA | 1 |
| Hirouchi, M; Kuriyama, K; Ohmori, Y; Taguchi, J | 1 |
| Bonanno, G; Giralt, MT; Raiteri, M | 1 |
| Bernardini, MC; Blandizzi, C; Del Tacca, M | 2 |
| Catt, KJ; Stojilković, SS; Virmani, MA | 1 |
| Morimoto, K; Nakamura, Y; Okamoto, M; Otsuki, S; Sato, K; Sato, M | 1 |
| Segal, M | 2 |
| Albin, RL; Chu, DC; Penney, JB; Young, AB | 1 |
| Drew, CA; Johnston, GA; Kerr, DI; Ong, J | 1 |
| Kohlenbach, A; Schlicker, E | 1 |
| Ferrendelli, JA; Miller, JW | 1 |
| Barraclough, CA; Hartman, RD; He, JR | 1 |
| Hösli, E; Hösli, L | 1 |
| Collingridge, GL; Davies, CH; Davies, SN | 1 |
| Friedman, DL; Redburn, DA | 1 |
| Kim, KH; Takeuchi, H | 1 |
| Baumann, PA; Waldmeier, PC | 1 |
| Kuriyama, K; Ohmori, Y | 1 |
| Maj, M; Monteleone, P; Steardo, L; Tanzillo, C | 1 |
| Mehta, AK; Ticku, MK | 1 |
| Balcar, VJ; Dreher, B | 1 |
| Iovino, M; Maj, M; Monteleone, P; Steardo, L | 1 |
| Michler, A | 1 |
| Bickford-Wimer, PC; Hoffer, BJ; Parfitt, KD | 1 |
| Boeckxstaens, GE; Herman, AG; Pelckmans, PA; Rampart, M; Ruytjens, IF; Van Maercke, YM; Verbeuren, TJ | 1 |
| Sved, AF; Sved, JC | 2 |
| Artemenko, DP; Gerasimov, VD | 1 |
| Cheun, JE; Lee, MB; Yeh, HH | 1 |
| Clements, JD; Forsythe, ID | 1 |
| Hicks, TP; Kaneko, T | 2 |
| Cardinali, DP; Chuluyan, HE; Rosenstein, RE | 1 |
| Kostowski, W; Pałejko, W; Plaznik, A; Stefański, R | 1 |
| Goto, Y; Hara, N; Hara, Y; Natsume, Y | 2 |
| Gage, PW; Saint, DA; Thomas, T | 1 |
| Slater, NT; Smith, RD; Turek, FW | 1 |
| Fukuda, H; Hirayama, T; Ono, H | 1 |
| Hall, RG; Johnston, GA; Kerr, DI; Ong, J | 1 |
| Khalil, A; Krantis, A; McKay, A | 1 |
| Harrison, NL | 1 |
| Malouf, AT; Robbins, CA; Schwartzkroin, PA | 1 |
| Mitsoglou, GM; Padjen, AL | 1 |
| Baba, M; Ichii, M; Iishi, H; Nakaizumi, A; Taniguchi, H; Tatsuta, M | 1 |
| Mizuno, M; Watanabe, K; Yano, S | 1 |
| Deisz, RA; Lux, HD | 1 |
| Taniyama, K | 1 |
| Persson, B; Rubenson, A; Sillén, U | 1 |
| Robertson, B; Taylor, WR | 1 |
| Ogata, N | 1 |
| Johnston, GA; Kerr, DI; Ong, J | 2 |
| Desarmenien, M; Desaulles, E; Feltz, P; Li Volsi, G; Schlichter, R | 1 |
| Akagi, H; Yanagisawa, M | 1 |
| Ciuffi, M; Franchi-Micheli, S; Luzzi, S; Rosi, E; Zilletti, L | 1 |
| Inoue, M; Matsuo, T; Ogata, N | 2 |
| Barnes, PJ; Belvisi, MG; Ichinose, M | 1 |
| Dutar, P; Lamour, Y; Rascol, O | 2 |
| Aley, KO; Kulkarni, SK | 2 |
| al-Dahan, MI; Thalmann, RH | 1 |
| Breslow, MF; Fankhauser, MP; Hope, DG; Meredith, KE; Misiaszek, J; Potter, RL | 1 |
| Andrioli, GC; Asaro, D; Bonanno, G; Cavazzani, P; Pellegrini, G; Raiteri, M | 1 |
| Gähwiler, BH; Thompson, SM | 1 |
| Johnston, GA; Kerr, DI; Ong, J; Prager, RH | 1 |
| Giuliani, S; Maggi, CA; Manzini, S; Meli, A | 1 |
| Masotto, C; Negro-Vilar, A; Wisniewski, G | 1 |
| Enna, SJ; Ferkany, JW; Karbon, EW; Scherer, RW | 1 |
| Bonanno, G; Fedele, E; Raiteri, M | 1 |
| Amenta, F; Erdö, SL; Ezer, E; Matuz, J; Wolff, JR | 1 |
| Menaker, M; Ralph, MR | 1 |
| Blasquez, C; Delbende, C; Jégou, S; Tranchand-Bunel, D; Vaudry, H | 1 |
| Agmo, A; Paredes, R; Soria, P | 1 |
| Harro, J; Kiivet, RA; Pŏld, M; Rägo, L | 1 |
| Bowen, DM; Cross, AJ; Francis, PT; Green, AR; Robinson, TN; Stirling, JM | 1 |
| Ikawa, K; Kariya, T; Motohashi, N | 1 |
| Erdö, SL; Michler, A | 1 |
| Burgoyne, RD; Robson, SJ | 1 |
| Baumann, PA; Feldtrauer, JJ; Waldmeier, PC; Wicki, P | 2 |
| Holden-Dye, L; Krogsgaard-Larsen, P; Nielsen, L; Walker, RJ | 1 |
| Candura, SM; Crema, A; Frigo, GM; Manzo, L; Onori, L; Rizzi, CA; Tonini, M | 1 |
| Bonanno, G; Cantoni, C; Pellegrini, G; Raiteri, M | 1 |
| Abbenante, J; Johnston, GA; Kerr, DI; Ong, J; Prager, RH | 1 |
| Gal'chenko, AA; Iarkov, AV; Kovalev, GI; Vorob'ev, VV | 1 |
| Enomoto, T; Nishikawa, T; Scatton, B; Shinohara, K; Takahashi, K | 1 |
| Karlsson, G; Olpe, HR | 1 |
| Malchow, RP; Qian, HH; Ripps, H | 1 |
| Ballejo, G; Calixto, JB; Strobel, GH | 1 |
| Hill, DR | 1 |
| Bingmann, D; Speckmann, EJ; Walden, J | 1 |
| Lacey, MG; Mercuri, NB; North, RA | 1 |
| Baker, JK; Wall, GM | 1 |
| Barat, A; Marsal, J; Ramírez, G; Solsona, C | 1 |
| Alabadí, JA; Alborch, E; Campos, V; Miranda, FJ; Salom, JB; Torregrosa, G | 1 |
| Beattie, DT; Berthelot, P; Curtis, DR; Debaert, M; Vaccher, C | 1 |
| Amatsu, M; Okada, Y; Yamauchi, R | 1 |
| Neal, MJ; Shah, MA | 1 |
| Misgeld, U; Müller, W | 1 |
| Chuang, DM; Zhu, XZ | 1 |
| Asaro, D; Pellegrini, G; Pittaluga, A; Raiteri, M | 1 |
| Dutar, P; Nicoll, RA | 1 |
| Rogier, CJ; Tunnicliff, G; Youngs, TL | 1 |
| Barker, JL; Harrison, NL; Lange, GD | 1 |
| Blair, AJ; Crawford, IL; Feldman, M; Petty, F; Stevens, MH; Taylor, IL; Thirlby, RC; Walsh, JH | 1 |
| Sedlácek, J | 1 |
| Zieglgänsberger, W | 1 |
| Aceves, J; Floran, B; Nava, C; Silva, I | 1 |
| Crawford, ML; Young, JM | 1 |
| Cañadas, S; Castro, E; Gimenez, G; González, MP; Oset-Gasque, MJ | 1 |
| Ciuffi, M; Franchi-Micheli, S; Gentilini, G; Gori, AM; Luzzi, S; Zilletti, L | 1 |
| Davrainville, JL; Khayari, A; Math, F | 1 |
| Albus, K; Baumfalk, U | 2 |
| Fujiwara, M; Kurahashi, K; Oikawa, H; Okamoto, T | 1 |
| Georgiev, V; Getova, D | 1 |
| Maurin, Y | 1 |
| Funase, K; Ohfune, Y; Shimamoto, K; Takeuchi, H; Yongsiri, A | 1 |
| Kontro, P; Oja, SS; Varga, V | 1 |
| Forziati, D; Iovino, M; Maj, M; Monteleone, P; Steardo, L; Veltro, F | 1 |
| Greentree, SG; Pertwee, RG; Swift, PA | 1 |
| Bitran, D; Leipheimer, RE; McQuade, DB; Miller, SA; Sachs, BD | 1 |
| Arakawa, T; Okada, Y | 1 |
| Connors, BW; Malenka, RC; Silva, LR | 1 |
| Davidoff, RA | 1 |
| Fukuda, H; Kato, K | 1 |
| Bousquet, P; Feldman, J; Schwartz, J | 1 |
| Evans, RH | 1 |
| Goddard, GV; Holmes, KH; Morimoto, K | 1 |
| Biscoe, TJ; Duchen, MR; Yu, YB | 1 |
| Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Cañadas, S; Castro, E; Gimenez, A; González, MP; Martinez, P; Oset-Gasque, MJ | 1 |
| Iwai, S; Shirakawa, J; Tanaka, C; Taniyama, K | 1 |
| Crunelli, V; Leresche, N; Lightowler, S; Soltesz, I | 1 |
| Lima, L; Sourkes, TL | 1 |
| Hilakivi, I; Hilakivi, LA; Loikas, P; Taira, T | 1 |
| Enna, SJ; Karbon, EW | 1 |
| Karobath, M; Supavilai, P | 1 |
| Brown, DA; Gähwiler, BH | 1 |
| Maggi, CA; Meli, A; Santicioli, P | 4 |
| Agmo, A; Tarasco, C | 1 |
| Gianutsos, G; Suzdak, PD | 4 |
| Hanada, S; Tanaka, C; Taniyama, K | 1 |
| Maggi, CA; Manzini, S; Meli, A | 1 |
| Giotti, A; Luzzi, S; Maggi, CA; Spagnesi, S; Zilletti, L | 1 |
| González-Viveros, MT; Meza, G; Ruiz, M | 1 |
| Ho, IK; Sivam, SP | 2 |
| Gordon-Weeks, PR; Lockerbie, RO | 1 |
| Agmo, A; Paredes, R | 1 |
| Awad, M; Fares, F; Gavish, M | 1 |
| Nakahiro, M; Saito, K; Yamada, I; Yoshida, H | 1 |
| Blaxter, TJ; Carlen, PL | 1 |
| Dickson, C; Sawynok, J | 2 |
| Maderdrut, JL; Oppenheim, RW; Reitzel, JL | 1 |
| Erdõ, SL; Riesz, M | 1 |
| Kannisto, P; Owman, C; Schmidt, G; Walles, B | 1 |
| Bloomfield, MR; Fillenz, M | 1 |
| Bristow, DR; Watling, KJ | 1 |
| Chweh, AY; Swinyard, EA; Ulloque, RA | 1 |
| Allan, AM; Harris, RA | 1 |
| Ault, B; Bragdon, AC; Sutch, CP; Swartzwelder, HS; Wilson, WA | 1 |
| Demeneix, BA; Feltz, P; Loeffler, JP; Taleb, O | 1 |
| Balcar, VJ; Dammasch, IE; Joó, F; Kása, P; Wolff, JR | 1 |
| Ciuffi, M; Franchi-Micheli, S; Luzzi, S; Zilletti, L | 1 |
| Goodwin, GM; Gray, JA; Green, AR; Metz, A | 1 |
| Morse, DE; Trapido-Rosenthal, HG | 1 |
| Strauss, P | 1 |
| Guidotti, A; Hanbauer, I | 1 |
| Curtis, DR; Gynther, BD; Malik, R | 1 |
| Baraldi, M; Benelli, A; Caselgrandi, E; Giberti, A; Preti, C; Sandrini, M; Tosi, G; Zanoli, P | 1 |
| Adjeroud, S; Bernard, C; Cazin, L; Danger, JM; Lamacz, M; Leneveu, E; Stoeckel, ME; Tappaz, ML; Tonon, MC; Vaudry, H | 1 |
| Jenks, BG; Lenssen, FJ; Vaudry, H; Verburg-van Kemenade, BM | 1 |
| Sawynok, J | 2 |
| Audi, EA; Graeff, FG | 1 |
| Lindgren, S | 1 |
| Zharkovskaia, TA; Zharkovskiĭ, AM | 1 |
| Gray, JA; Green, AR | 1 |
| Bhisitkul, RB; Kocsis, JD; Villa, JE | 1 |
| Miñano, FJ; Pascual, J; Sancibrián, M; Serrano, JS | 1 |
| Ciuffi, M; Franchi-Micheli, S; Luzzi, S; Rosi, E; Spagnesi, S; Zilletti, L | 1 |
| Pirkle, WH; Smith, DF | 1 |
| Håkanson, R; Kannisto, P; Owman, C; Schmidt, G; Wahlestedt, C | 1 |
| Aghajanian, GK; Innis, RB; Nestler, EJ | 1 |
| Martin, A; Martin, C; Rud, C; Valli, M | 1 |
| McLamb, RL; Sidel, ES; Swartzwelder, HS; Tilson, HA; Wilson, WA | 1 |
| Catelli, JM; Sved, AF | 1 |
| Kimura, H; Uemura, S | 1 |
| Höglund, U; Lindgren, S; Westerling, P | 1 |
| Calogero, AE; Chrousos, GP; Gallucci, WT; Gold, PW | 1 |
| Akaike, N; Behrends, JC; Maruyama, T | 1 |
| Howe, JR; Sutor, B; Zieglgänsberger, W | 1 |
| Kruszewska, A | 1 |
| Klockgether, T; Schwarz, M; Sontag, KH; Turski, L; Wüllner, U | 1 |
| Janigro, D; Schwartzkroin, PA | 1 |
| Crunelli, V; Haby, M; Jassik-Gerschenfeld, D; Leresche, N; Pirchio, M | 1 |
| Cortesini, C; Franchi-Micheli, S; Gentilini, G; Luzzi, S; Pantalone, D; Zilletti, L | 1 |
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| Faraji, F; Ghasemi, A; Motamedi, F; Zahediasl, S | 1 |
| Ayajiki, K; Kobuchi, S; Matsumura, Y; Ohkita, M; Shintani, T; Suzuki, R; Tanaka, R; Tsutsui, H | 1 |
| Chen, L; Luo, B; Su, YY; Wang, HT; Wu, SH | 1 |
| Deng, A; Goodey, R; Lobarinas, E; Lu, J; Salvi, RJ; Stolzberg, D; Sun, W | 1 |
| Blaskiewicz, R; Goldkamp, J; Myles, T | 1 |
| Lundbye-Jensen, J; Nielsen, JB; Petersen, TH; Willerslev-Olsen, M | 1 |
| Antal, K; Cselenyák, A; Emri, Z; Katarova, Z; Kwakowsky, A; Lacza, Z; Schwirtlich, M; Szabó, G | 1 |
| Leigh, RJ; Optican, LM; Shaikh, AG; Thurtell, MJ | 1 |
| Aono, Y; Cools, AR; Koshikawa, N; Oi, Y; Saigusa, T; Sekino, R; Takada, K; Uchida, T | 1 |
| Kim, YS; Lee, IO; Lim, ES; Son, JK | 1 |
| Augustin, M; Pogatzki-Zahn, EM; Reichl, S; Zahn, PK | 1 |
| Bonaventura, MM; Crivello, M; Cymeryng, C; Ferreira, ML; Libertun, C; Lux-Lantos, VA; Repetto, M | 1 |
| Khlebtsova, EB; Magomedov, MM; Samotrueva, MA; Tiurenkov, IN | 1 |
| Fei, SJ; Li, TT; Liu, ZB; Qiao, X; Zhang, JF; Zhu, JZ; Zhu, SP | 1 |
| Chen, SH; Li, SF; Lin, CT; Lue, JH; Tsai, YJ; Wang, HY | 1 |
| Lalive, AL; Luján, R; Lüscher, C; Martínez-Hernández, J; Moss, SJ; Munoz, MB; Padgett, CL; Pangalos, MN; Slesinger, PA; Tan, KR; Terunuma, M; Watanabe, M | 1 |
| Hanafusa, N; Kawasaki, H; Okamoto, K; Takatori, S | 1 |
| Di Prisco, S; Grilli, M; Marchi, M; Pittaluga, A; Summa, M; Usai, C | 1 |
| Kennard, C; Mehta, AR | 1 |
| Heinzlef, O; Monteil-Roch, I | 1 |
| Man'shina, NG; Safonov, VA; Tarakanov, IA; Vediasova, OA | 1 |
| Bolton, MM; Heaney, CF; Kinney, JW; Magcalas, CM; Murtishaw, AS; Sabbagh, JJ | 1 |
| Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Mishima, K; Niki, T; Oishi, R; Shirakawa, A | 1 |
| Cohen, SM; Misono, S | 1 |
| Balchand, K; Paton-Gay, CL; Rehm, J; Samokhvalov, AV | 1 |
| Cui, N; Jiang, C; Jin, X; Jin, XT; Zhong, W | 1 |
| Dacks, AM; Weiss, KR | 1 |
| Martire, M; Samengo, IA; Scotti, V | 1 |
| Atkinson, MA; Chen, Z; Dang, H; Guan, A; Jin, Y; Kaufman, DL; Tian, J | 1 |
| Chen, RX; Hou, XL; Lv, Y; Wu, YL; Xu, XQ; Zhu, Y | 1 |
| Benoliel, R; Haviv, Y; Sharav, Y; Zadik, Y | 1 |
| Bak, K; Bleeker, J; Cavaletti, G; Chauhan, C; Dworkin, RH; Gavin, P; Hershman, DL; Lacchetti, C; Lavino, A; Lavoie Smith, EM; Loprinzi, CL; Lustberg, MB; Paice, J; Schneider, B; Smith, ML; Smith, T; Terstriep, S; Wagner-Johnston, N | 1 |
| Collins, AC; Grady, SR; Marks, MJ; McClure-Begley, TD; Stitzel, JA | 1 |
| Fink, K; Harms, L; Hellweg, R; Kronenberg, G; Kunte, H | 1 |
| Dargan, PI; Green, JL; Kapil, V; Le Lait, MC; Wood, DM | 1 |
| Marino, V; Ong, J; Parker, DA | 1 |
| Budefeld, T; Carbone, D; Eitel, C; Handa, RJ; Majdic, G; Nash, C; Searcy, BT; Staros, M; Stratton, MS; Tobet, SA | 1 |
| Caffino, L; Castelnovo, LF; Cavalli, E; Colciago, A; Faroni, A; Magnaghi, V; Pajardi, G; Procacci, P | 1 |
| Glinka, Y; Hasilo, C; Paraskevas, S; Prud'homme, GJ; Udovyk, O; Wang, Q | 1 |
| Adelfinger, L; Besseyrias, V; Bettler, B; Fritzius, T; Gassmann, M; Jacquier, V; Rajalu, M | 1 |
| Auger, ML; Floresco, SB | 1 |
| Amakhin, DV; Popov, VA; Veselkin, NP | 1 |
| Borgland, SL; MacLeod, B; Pitman, KA; Puil, E | 1 |
| Chrobok, Ł; Lewandowski, MH; Palus, K | 1 |
| Arima, H; Bettler, B; Itohara, S; Iwasato, T; Koide, T; Lee, RX; Miczek, KA; Takahashi, A | 1 |
| Carvalho, P; de Vries, MG; Martins, I; Tavares, I; Teixeira-Pinto, A; Westerink, BHC; Wilson, SP | 1 |
| Finn, MG; Kaczanowska, K; Li, X; Markou, A; Risbrough, VB | 1 |
| Hu, P; Hu, Y; Liu, J; Rondard, P; Sun, Q; Tu, H; Wang, Y; Xu, C; Zhang, W | 1 |
| Bagmetova, VV; Krivitskaya, AN; Tyurenkov, IN | 1 |
| Borisova, T; Dudarenko, M; Pozdnyakova, N | 1 |
| Du, X; Gamper, N; Huang, D; Huang, S; Peers, C; Zhang, H | 1 |
| Fox, M; Schneemann, M; Steger, M | 1 |
| Chen, Q; Ding, L; Gao, R; Gao, XY; Kang, YM; Li, YH; Xiong, XQ; Zhu, GQ | 1 |
| Banov, D; Bassani, AS | 1 |
| Hatam, M; Nasimi, A; Rasoulpanah, M | 1 |
| Barson, JR; Leibowitz, SF | 1 |
| Ban Uelos, C; Beas, BS; Bizon, JL; McQuail, JA; Setlow, B | 1 |
| Trojano, M | 1 |
| Bagmetova, VV; Berestovitskaya, VM; Borodkina, LE; Tyurenkov, IN; Vasil'eva, OS | 1 |
| Hanaoka, K; Ikegaya, Y; Komatsu, T; Matsuki, N; Nagano, T; Naka, M; Nomura, H; Takeda, A; Terai, T; Ueno, T; Urano, Y | 1 |
| Jiang, H; Jin, Q; Li, G; Li, Y; Lv, J; Wan, P; Wang, J | 1 |
| Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P | 1 |
| Gratton, A; Lupinsky, D; Moquin, L | 1 |
| Li, J; Liu, C; Lu, WY; Wang, S; Xiang, YY; Yi, F; Zhu, J | 1 |
| Bongioanni, P; Diana, A; Miller, RG; Moore, DH; O'Keeffe, AG; Pillai, R | 1 |
| Chang, S; Choi, KH; Gwak, YS; Jang, EY; Jin, W; Kim, HY; Kim, JH; Kim, MS; Koo, H; Lee, BH; Lee, JG; Lee, JY; Ryu, YH; Steffensen, SC; Yang, CH; Yoon, SS | 1 |
| Andrews, R; Nahar, L; Patel, R; Paterson, S; Smith, A | 1 |
| Bogatyrev, S; Tzschentke, B; Yakimova, KS | 1 |
| Takahashi, M; Tanaka, J | 1 |
| Lyon, J | 1 |
| Friend, SF; Jimenez, B; Joshi, YB; Steiger, LR | 1 |
| Bardenheuer, HJ; Hollmann, MW; Kessler, J; Kohse, EK | 1 |
| Brodkin, ES; Carlson, GC; Dow, HC; Gajewski, C; Hirano, S; Krizman, E; Port, RG; Roberts, TPL; Robinson, MB; Siegel, SJ | 1 |
| Chang, CH; Grace, AA | 1 |
| Agier, MS; Bailly, S; Joyeux-Faure, M; Jullian-Desayes, I; Lador, F; Mallaret, M; Pépin, JL; Revol, B; Tamisier, R | 1 |
| Bolser, DC; Jakus, J; Kotmanova, Z; Martvon, L; Misek, J; Musselwhite, MN; Pitts, T; Poliacek, I; Shen, TY; Simera, M; Veternik, M | 1 |
| Dodridge, CS; Evans, JR; Garcia-Finana, M; Hanna, K; Howard, C; Jarvis, KA; Maan, T; MacDiarmid, SL; Noonan, CP; North, L; Rodgers, H; Rowe, FJ | 1 |
| Alabed, S; Bergman, H; Latifeh, Y; Mohammad, HA | 1 |
| Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R | 1 |
| Barreiro-Iglesias, A; Fernández-López, B; Hanslik, K; Ledo-García, R; Morgan, JR; Rodicio, MC; Romaus-Sanjurjo, D | 1 |
| Hardman, MI; Sprung, J; Weingarten, TN | 1 |
| Bocian, R; Broncel, A; Konopacki, J; Kłos-Wojtczak, P | 1 |
| Braun, C; Carboni, M; Fioravanti, C; Kajal, SD; Mazzetti, C; Ziemann, U | 1 |
| Candiotti, KA; Gitlin, M; Rodriguez-Blanco, YF; Sevilla, A; Su, C; Weller, R; Wu, J; Yang, J; Zhang, Y; Zheng, C | 1 |
| Cao, K; Liang, H; Luo, W; Tan, D; Tan, Y; Tian, N; Wang, X; Zhang, Q | 1 |
| Bank, J; Bartos, M; Booker, SA; Elgueta, C; Harada, H; Kulik, A; Vida, I | 1 |
| Kent, CN; Lindsley, CW; Park, C | 1 |
| Brigo, F; Golaszewski, S; Nardone, R; Pucks-Faes, E; Saltuari, L; Sebastianelli, L; Trinka, E; Versace, V | 1 |
| Irie, T; Kikura-Hanajiri, R; Yamazaki, D | 1 |
| Albagli, O; Armanet, M; Hamroune, J; Marullo, S; Maugein, A; Pechberty, S; Rachdi, L; Ravassard, P; Scharfmann, R | 1 |
| Araghi, F; Aryannejad, A; Dadkhahfar, S; Dehpour, AR; Mohammad Jafari, R; Noroozi, N; Tabary, M; Tavangar, SM | 1 |
| Hirono, M; Yanagawa, Y | 1 |
| Bailey, T; Kaczanowska, K; McDonald, P; Nieto, A | 1 |
| Alizadeh-Sani, M; Foroumadi, A; Hasanvand, Z; Jouyban, A; Mohammadian, E; Rahimpour, E | 1 |
| Bouchet, CA; Ingram, SL; Li, MH; McPherson, KB; Traynor, JR | 1 |
| Axelsson, SFA; Horiguchi, N; Horst, NK; Robbins, TW; Roberts, AC | 1 |
| Holland, A; Murray, A; VanDreese, B | 1 |
| Escorihuela, J; Fustero, S; Han, J; Landa, A; Soloshonok, VA; Sorochinsky, A | 1 |
| Guo, J; Li, JW; Li, RQ; Mei, JJ; Wang, YY; Zhang, JY; Zhang, LH | 1 |
60 review(s) available for baclofen and gamma-aminobutyric acid
| Article | Year |
|---|---|
Neuropharmacology of amino acid inhibitory transmitters.
Topics: Amino Acids; Animals; Baclofen; Barbiturates; Benzodiazepines; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Humans; Neurotransmitter Agents | 1978 |
GABA and epilepsy: their complex relationship and the evolution of our understanding.
Topics: Baclofen; Brain; Epilepsy; gamma-Aminobutyric Acid; Humans; Receptors, GABA-A | 1992 |
Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters.
Topics: Animals; Baclofen; Electric Conductivity; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Neurotransmitter Agents; Receptors, GABA-A; Receptors, GABA-B; Snails | 1992 |
GABAA and GABAB receptors and the ionic mechanisms mediating their effects on locus coeruleus neurons.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Cations, Divalent; Feedback; gamma-Aminobutyric Acid; Ion Channel Gating; Locus Coeruleus; Neurons; Norepinephrine; Rats; Receptors, GABA-A | 1991 |
GABA: an excitatory transmitter in early postnatal life.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Central Nervous System; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Hippocampus; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1991 |
Presynaptic GABA receptors.
Topics: Animals; Baclofen; Bicuculline; Brain; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Homeostasis; Muscimol; Receptors, GABA-A; Receptors, Neurotransmitter; Tissue Distribution | 1990 |
[GABAergic neurons in the mammalian intestine].
Topics: Animals; Autonomic Fibers, Postganglionic; Autoradiography; Baclofen; Calcium; Digestive System; gamma-Aminobutyric Acid; Gastrointestinal Motility; Glutamate Decarboxylase; Guinea Pigs; Histocytochemistry; Humans; In Vitro Techniques; Muscimol; Myenteric Plexus; Potassium; Rabbits; Rats; Receptors, GABA-A; Substance P; Synaptic Transmission; Vasoactive Intestinal Peptide | 1985 |
Dorsal horn neuropharmacology: baclofen and morphine.
Topics: Animals; Baclofen; Endorphins; gamma-Aminobutyric Acid; Humans; Morphine; Narcotics; Neurons; Receptors, Opioid; Spinal Cord; Stereoisomerism; Synapses | 1988 |
Antispasticity drugs: mechanisms of action.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Central Nervous System; Dantrolene; gamma-Aminobutyric Acid; Glycine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Neurotransmitter Agents; Phenothiazines; Rats; Receptors, Neurotransmitter; Spinal Cord | 1985 |
[GABA and central regulation of cardiovascular function].
Topics: Angiotensin II; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Baclofen; Benzodiazepines; Bicuculline; Blood Pressure; Brain Mapping; Cardiovascular Physiological Phenomena; Cardiovascular System; Cats; Central Nervous System; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Muscimol; Rabbits; Reflex; Reticular Formation; Synaptic Transmission; Vasomotor System; Vasopressins | 1985 |
Pharmacology of amino acid receptors on vertebrate primary afferent nerve fibres.
Topics: Animals; Baclofen; Barbiturates; Bicuculline; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Kainic Acid; Neurons, Afferent; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, GABA-A; Structure-Activity Relationship | 1986 |
GABA in morphine analgesia and tolerance.
Topics: Analgesia; Animals; Baclofen; Benzodiazepines; Bicuculline; Brain Chemistry; Cyclohexanecarboxylic Acids; Drug Tolerance; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Morphine; Muscimol; Naloxone; Picrotoxin; Rats; Receptors, GABA-A; Synaptic Transmission | 1985 |
GABAergic mechanisms of analgesia: an update.
Topics: Analgesia; Animals; Baclofen; Biogenic Amines; Catecholamines; gamma-Aminobutyric Acid; Narcotics; Receptors, GABA-A | 1987 |
Baclofen reduces post-synaptic potentials of rat cortical neurones by an action other than its hyperpolarizing action.
Topics: Action Potentials; Amino Acids; Animals; Aspartic Acid; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Inbred Strains; Stereoisomerism; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Time Factors | 1987 |
The interaction between GABA and dopamine: implications for schizophrenia.
Topics: Animals; Antipsychotic Agents; Baclofen; Brain Chemistry; Catalepsy; Dopamine; gamma-Aminobutyric Acid; Humans; Motor Activity; Neural Pathways; Neurons; Rats; Receptors, Dopamine; Rotation; Schizophrenia; Sodium Oxybate; Stereotyped Behavior; Valproic Acid | 1983 |
gamma-Aminobutyric acid and cardiovascular function.
Topics: Animals; Atropine; Baclofen; Blood Pressure; GABA Antagonists; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Vagotomy | 1983 |
GABA and respiratory function.
Topics: Animals; Baclofen; GABA Antagonists; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Iontophoresis; Medulla Oblongata; Muscimol; Respiration | 1984 |
The development of epilepsy in the paediatric brain.
Topics: Age Factors; Animals; Baclofen; Child; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Humans; Infant, Newborn; Kainic Acid; Kindling, Neurologic; Phenytoin; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate | 1994 |
Astrocytic GABA receptors.
Topics: Animals; Astrocytes; Baclofen; Barbiturates; Benzodiazepines; Carbolines; Cats; Chloride Channels; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Humans; Membrane Potentials; Muscimol; Nerve Tissue Proteins; Neurons; Neurotoxins; Pituitary Gland; Rats; Receptors, GABA; Second Messenger Systems; Synaptic Transmission | 1994 |
GABAB receptors in the lung.
Topics: Anaphylaxis; Animals; Baclofen; Cough; gamma-Aminobutyric Acid; Humans; Lung; Neurons, Afferent; Parasympathetic Nervous System; Receptors, GABA-A; Tachykinins | 1993 |
The neurochemistry of central pain: evidence from clinical studies, hypothesis and therapeutic implications.
Topics: Anesthetics, Intravenous; Baclofen; Cerebral Cortex; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Midazolam; Middle Aged; Pain; Propofol; Thalamus | 1998 |
GABAB receptors: drugs meet clones.
Topics: Baclofen; Brain Chemistry; Cloning, Molecular; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Receptors, GABA-B; Signal Transduction | 1998 |
Neuropharmacologic aspects of the ocular motor system and the treatment of abnormal eye movements.
Topics: Abducens Nerve; Acetates; Amines; Baclofen; Cranial Nerve Diseases; Cyclohexanecarboxylic Acids; Eye Movements; Fixation, Ocular; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypoglossal Nerve; Ocular Motility Disorders; Vestibular Nerve; Visual Pathways | 1999 |
GABA modulation of cocaine self-administration.
Topics: Animals; Baclofen; Cocaine; Conditioning, Psychological; gamma-Aminobutyric Acid; Organophosphonates; Phosphinic Acids; Reinforcement, Psychology; Self Administration | 2000 |
Pharmacotherapy of spasticity: oral medications and intrathecal baclofen.
Topics: Acetates; Administration, Oral; Amines; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Cerebral Palsy; Child, Preschool; Cyclohexanecarboxylic Acids; Dantrolene; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Muscle Relaxants, Central | 2001 |
GABA agonists and gabapentin for spastic hypertonia.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Diazepam; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Spasticity | 2001 |
Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug.
Topics: Animals; Anticonvulsants; Baclofen; Brain; Diazepam; Dopamine Agonists; Dyskinesias; Emotions; GABA Agonists; gamma-Aminobutyric Acid; Humans; Mental Disorders; Nootropic Agents; Phenethylamines; Piracetam; Stereoisomerism; Structure-Activity Relationship; Tranquilizing Agents | 2001 |
GABA(B) receptor agonists for the treatment of drug addiction: a review of recent findings.
Topics: Animals; Baclofen; Brain; Dopamine; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Reinforcement, Psychology; Substance-Related Disorders | 2002 |
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabinoids; Causalgia; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Dystonia; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Mechanoreceptors; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Pain; Physical Therapy Modalities; Receptors, GABA-A; Receptors, GABA-B; Relaxation Therapy; Trigeminal Neuralgia | 2001 |
A new role for GABA: inhibition of tumor cell migration.
Topics: Animals; Baclofen; Cell Movement; GABA Agonists; gamma-Aminobutyric Acid; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Receptors, GABA-B; Signal Transduction | 2003 |
A GABA(B) mystery: the search for pharmacologically distinct GABA(B) receptors.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Benzylamines; Cyclohexanecarboxylic Acids; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Molecular Structure; Morpholines; Phosphinic Acids; Protein Isoforms; Receptors, GABA-B; RNA, Messenger | 2001 |
Gabapentin for intractable hiccup.
Topics: Acetates; Aged; Amines; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guillain-Barre Syndrome; Hiccup; Humans; Male; Muscle Relaxants, Central; Tomography, X-Ray Computed | 2004 |
Antispasticity medications: uses and limitations of enteral therapy.
Topics: 4-Aminopyridine; Acetates; Adrenergic alpha-Agonists; Amines; Baclofen; Benzodiazepines; Cyclohexanecarboxylic Acids; Cyproheptadine; Dantrolene; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Glycine; Humans; Muscle Relaxants, Central; Muscle Spasticity; Neuroprotective Agents; Piracetam; Serotonin Antagonists | 2004 |
My close encounter with GABA(B) receptors.
Topics: Animals; Baclofen; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; gamma-Aminobutyric Acid; Humans; Potassium Channels, Inwardly Rectifying; Receptors, GABA-B; Synaptic Transmission | 2004 |
[Botulinum toxin type A in the treatment plan for cerebral palsy].
Topics: Activities of Daily Living; Adolescent; Adult; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Gait; gamma-Aminobutyric Acid; Humans; Injections, Intramuscular; Longitudinal Studies; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Physical Therapy Modalities; Prospective Studies; Quality of Life | 2001 |
Management issues of neuropathic trigeminal pain from a medical perspective.
Topics: Amines; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents; Baclofen; Carbamazepine; Cranial Nerve Injuries; Cyclohexanecarboxylic Acids; Facial Neuralgia; Facial Pain; Gabapentin; gamma-Aminobutyric Acid; Herpes Zoster; Humans; Lamotrigine; Narcotics; Phenytoin; Triazines; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2004 |
[Chronic intrathecal drug administration for the control of intractable pain].
Topics: Amines; Analgesics, Opioid; Anesthetics, Local; Baclofen; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Morphine; Neoplasms; Neuralgia; omega-Conotoxins; Pain, Intractable | 2008 |
[Pharmacotherapy of central oculomotor disorders].
Topics: 4-Aminopyridine; Amifampridine; Amines; Baclofen; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Gabapentin; gamma-Aminobutyric Acid; Humans; Magnetic Resonance Imaging; Memantine; Nystagmus, Pathologic; Vestibular Nuclei | 2008 |
[GABA(B) receptors and sensitization to pain].
Topics: 14-3-3 Proteins; Allosteric Regulation; Animals; Baclofen; Calcium Channels; Calcium-Binding Proteins; Chronic Disease; Dimerization; Extracellular Matrix Proteins; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Hyperalgesia; Mice; Mice, Knockout; Nerve Tissue Proteins; Nociceptors; Pain; Posterior Horn Cells; Presynaptic Terminals; Rats; Receptors, GABA-B | 2009 |
[Nystagmus in ophthalmology].
Topics: Amines; Baclofen; Cyclohexanecarboxylic Acids; Diagnostic Techniques, Ophthalmological; Eye Diseases; Gabapentin; gamma-Aminobutyric Acid; Humans; Nervous System Diseases; Nystagmus, Pathologic; Nystagmus, Physiologic; Ophthalmologic Surgical Procedures | 2009 |
The pharmacological treatment of nystagmus: a review.
Topics: Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Nystagmus, Congenital; Nystagmus, Pathologic; Randomized Controlled Trials as Topic | 2009 |
Clozapine, GABA(B), and the treatment of resistant schizophrenia.
Topics: Antipsychotic Agents; Baclofen; Clozapine; Drug Resistance; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Schizophrenia; Smoking; Tobacco Use Disorder; Transcranial Magnetic Stimulation | 2009 |
Spasticity: revisiting the role and the individual value of several pharmacological treatments.
Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Relaxants, Central; Muscle Spasticity; Recovery of Function; Treatment Outcome | 2010 |
The pharmacological treatment of acquired nystagmus.
Topics: Amines; Aminopyridines; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Nystagmus, Congenital; Nystagmus, Pathologic; Randomized Controlled Trials as Topic; Treatment Outcome | 2012 |
[Pharmacological treatment of spasticity in multiple sclerosis].
Topics: Algorithms; Amines; Baclofen; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Double-Blind Method; Drug Therapy, Combination; Gabapentin; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Nerve Block; Neuromuscular Agents; Randomized Controlled Trials as Topic; Spasm; Vigabatrin | 2012 |
Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review.
Topics: Amines; Amitriptyline; Baclofen; Chronic Disease; Cough; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neurotransmitter Agents; Pregabalin; Quality of Life | 2013 |
Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: American Society of Clinical Oncology clinical practice guideline.
Topics: Adult; Amines; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplastic Agents; Baclofen; Comorbidity; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Duloxetine Hydrochloride; Evidence-Based Medicine; Gabapentin; gamma-Aminobutyric Acid; Gels; Humans; Incidence; Ketamine; Neoplasms; Neuralgia; Peripheral Nervous System Diseases; Quality of Life; Randomized Controlled Trials as Topic; Severity of Illness Index; Survivors; Thiophenes; Treatment Outcome; United States | 2014 |
Systemic review: the pathogenesis and pharmacological treatment of hiccups.
Topics: Amines; Anticonvulsants; Antipsychotic Agents; Baclofen; Benzamides; Chlorpromazine; Cyclohexanecarboxylic Acids; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Metoclopramide; Randomized Controlled Trials as Topic; Treatment Outcome | 2015 |
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol | 2016 |
Gamma aminobutyric acid (GABA) modulators for amyotrophic lateral sclerosis/motor neuron disease.
Topics: Adult; Amyotrophic Lateral Sclerosis; Baclofen; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; GABA Agents; gamma-Aminobutyric Acid; Humans; Randomized Controlled Trials as Topic; Time Factors | 2017 |
Chronic Hiccups: An Underestimated Problem.
Topics: Amines; Anesthesiology; Baclofen; Chronic Disease; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hiccup; Humans; Muscle Relaxants, Central | 2017 |
Interventions for eye movement disorders due to acquired brain injury.
Topics: 4-Aminopyridine; Abducens Nerve Diseases; Amifampridine; Amines; Baclofen; Botulinum Toxins; Brain Injuries; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Neuromuscular Agents; Nystagmus, Pathologic; Ocular Motility Disorders; Randomized Controlled Trials as Topic; Vision, Binocular; Watchful Waiting | 2018 |
Gamma-aminobutyric acid agonists for antipsychotic-induced tardive dyskinesia.
Topics: Antipsychotic Agents; Baclofen; Dyskinesia, Drug-Induced; GABA Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Placebos; Randomized Controlled Trials as Topic; Valproic Acid | 2018 |
Pharmacological therapies for management of opium withdrawal.
Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol | 2018 |
Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.
Topics: Akathisia, Drug-Induced; Baclofen; Cyproheptadine; Dexmedetomidine; Diphenhydramine; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Haloperidol; Humans; Lorazepam; Male; Melatonin; Neuroleptic Malignant Syndrome; Olanzapine; Receptors, GABA; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult | 2019 |
Classics in Chemical Neuroscience: Baclofen.
Topics: Alcoholism; Baclofen; Brain; gamma-Aminobutyric Acid; Humans; Neurosciences; Receptors, GABA-B | 2020 |
Effects of intrathecal baclofen therapy in subjects with disorders of consciousness: a reappraisal.
Topics: Baclofen; Consciousness; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity | 2020 |
GABA
Topics: Baclofen; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Receptors, GABA-B; Seizures | 2022 |
Derivatization of γ-Amino Butyric Acid Analogues for Their Determination in the Biological Samples and Pharmaceutical Preparations: A Comprehensive Review.
Topics: Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Pharmaceutical Preparations; Pregabalin; Vigabatrin | 2022 |
Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives.
Topics: Baclofen; gamma-Aminobutyric Acid; Pregabalin; Stereoisomerism | 2022 |
14 trial(s) available for baclofen and gamma-aminobutyric acid
| Article | Year |
|---|---|
gamma-Aminobutyric acid enhances the tone of human internal anal sphincter.
Topics: Anal Canal; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Humans; Muscimol; Muscle Contraction; Muscle Relaxation; Pressure; Receptors, GABA-A; Valproic Acid | 1991 |
Reduction of baclofen-, but not sodium valproate-induced growth hormone release in type I diabetic men.
Topics: Adult; Baclofen; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Receptors, GABA-A; Valproic Acid | 1991 |
Role of gamma-aminobutyric acid in antipanic drug efficacy.
Topics: Anxiety Disorders; Baclofen; Clinical Trials as Topic; Double-Blind Method; Fear; gamma-Aminobutyric Acid; Humans; Panic; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Receptors, GABA-A | 1989 |
Baclofen-induced growth hormone secretion is blunted in chronic schizophrenics: neuroendocrine evidence for a GABA disturbance in schizophrenia.
Topics: Adult; Aged; Baclofen; Brain; Chronic Disease; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Middle Aged; Receptors, GABA-A; Schizophrenia | 1988 |
[Comparative study of sodium valproate and ketoprofen in the treatment of postoperative pain].
Topics: Adult; Baclofen; Clinical Trials as Topic; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Ketoprofen; Male; Middle Aged; Pain, Postoperative; Phenylpropionates; Valproic Acid | 1988 |
GABA and movement disorders.
Topics: Anticonvulsants; Baclofen; Clinical Trials as Topic; Double-Blind Method; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Humans; Huntington Disease; Isoniazid; Movement Disorders; Muscimol; Parkinson Disease; Valproic Acid | 1981 |
A possible role of gamma-aminobutyric acid in the control of the endocrine pancreas.
Topics: Administration, Oral; Adult; Baclofen; Blood Glucose; Female; gamma-Aminobutyric Acid; Glucagon; Glucose; Growth Hormone; Humans; Insulin; Islets of Langerhans; Male; Middle Aged | 1982 |
Baclofen administration for the treatment of affective disorders in alcoholic patients.
Topics: Administration, Oral; Adult; Alcoholism; Amitriptyline; Anxiety Disorders; Baclofen; Blood Platelets; Depressive Disorder; Diazepam; Dopamine; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Humans; Male; Monoamine Oxidase; Personality Inventory; Receptors, GABA-A; Receptors, GABA-B; Serotonin | 1993 |
A double-blind controlled study of gabapentin and baclofen as treatment for acquired nystagmus.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Double-Blind Method; Eye Movements; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Nystagmus, Pathologic; Treatment Outcome; Visual Acuity | 1997 |
Different control mechanisms of growth hormone (GH) secretion between gamma-amino- and gamma-hydroxy-butyric acid: neuroendocrine evidence in Parkinson's disease.
Topics: Aged; Baclofen; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Middle Aged; Parkinson Disease; Sodium Oxybate; Valproic Acid | 1997 |
Baclofen is effective in intractable hiccups induced by brainstem lesions.
Topics: Adult; Aged; Baclofen; Brain Stem; Brain Stem Infarctions; Chronic Disease; GABA Agonists; gamma-Aminobutyric Acid; Hiccup; Humans; Middle Aged; Neural Inhibition; Prospective Studies; Reflex; Synaptic Transmission; Treatment Outcome | 2001 |
Randomized, placebo-controlled trial of baclofen and gabapentin for the treatment of methamphetamine dependence.
Topics: Adult; Amines; Anti-Anxiety Agents; Baclofen; Central Nervous System Stimulants; Cyclohexanecarboxylic Acids; Demography; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Methamphetamine; Psychology; Substance-Related Disorders; Surveys and Questionnaires | 2006 |
The effect of baclofen and diazepam on motor skill acquisition in healthy subjects.
Topics: Adult; Baclofen; Brain Chemistry; Diazepam; Female; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Learning; Male; Motor Skills; Movement; Neural Inhibition; Young Adult | 2011 |
Inhibition in the somatosensory system: An integrative neuropharmacological and neuroimaging approach.
Topics: Adult; Alprazolam; Baclofen; Double-Blind Method; Ethanol; Evoked Potentials, Somatosensory; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Magnetoencephalography; Male; Neural Inhibition; Somatosensory Cortex; Touch Perception; Young Adult | 2019 |
1052 other study(ies) available for baclofen and gamma-aminobutyric acid
| Article | Year |
|---|---|
3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies.
Topics: Animals; Baclofen; Binding, Competitive; Brain; Chemical Phenomena; Chemistry; Furans; gamma-Aminobutyric Acid; Molecular Structure; Muscimol; Rats; Receptors, GABA-A; Synaptic Membranes; Thiophenes | 1991 |
Synthesis and biochemical evaluation of baclofen analogues locked in the baclofen solid-state conformation.
Topics: Animals; Baclofen; Binding, Competitive; Cell Membrane; gamma-Aminobutyric Acid; Indicators and Reagents; Models, Molecular; Molecular Conformation; Molecular Structure; Receptors, GABA-A; Structure-Activity Relationship; X-Ray Diffraction | 1991 |
Stereoselective syntheses of the trans-decahydroquinoline-5-carboxylic acid epimers. Diastereomeric zwitterionic probes of gamma-aminobutyric acid related biological properties in vitro and in vivo.
Topics: Animals; Brain; Chemical Phenomena; Chemistry; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Magnetic Resonance Spectroscopy; Mice; Quinolines; Rats; Receptors, GABA-A; Seizures; Stereoisomerism | 1986 |
Synthesis and pharmacological evaluation of gamma-aminobutyric acid analogues. New ligand for GABAB sites.
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, GABA-B; Stereoisomerism; Structure-Activity Relationship | 1987 |
Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists.
Topics: Animals; Behavior, Animal; Cats; Crystallography, X-Ray; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Organophosphonates; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Stereoisomerism; Structure-Activity Relationship | 1995 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies.
Topics: Caffeic Acids; Carboxylic Acids; Catalytic Domain; Chlorogenic Acid; Curcumin; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Models, Molecular; Molecular Structure; Protein Binding | 2009 |
Evaluation of difluoromethyl ketones as agonists of the γ-aminobutyric acid type B (GABAB) receptor.
Topics: Animals; Behavior, Animal; Female; GABA-B Receptor Agonists; Halogenation; Ketones; Male; Mice; Models, Molecular; Protein Conformation; Receptors, GABA-B | 2013 |
New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.
Topics: Animals; Benzocycloheptenes; Binding Sites; Binding, Competitive; Brain; Carboxylic Acids; Cell Line; Central Nervous System; Cyclopentanes; Drug Stability; gamma-Aminobutyric Acid; Hydroxybutyrates; Kinetics; Ligands; Male; Models, Chemical; Molecular Structure; Radioligand Assay; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Tritium | 2013 |
Targeting of N-Type Calcium Channels via GABA
Topics: Analgesics; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Conotoxins; Drug Discovery; HEK293 Cells; Humans; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Structure-Activity Relationship | 2018 |
[The contribution of drug research to the understanding of schizophrenia].
Topics: Adult; Amphetamines; Animals; Antipsychotic Agents; Baclofen; Chlorpromazine; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Haloperidol; Humans; Limbic System; Male; Methyltyrosines; Norepinephrine; Rats; Reserpine; Schizophrenia; Synaptic Transmission; Thioridazine; Tyrosine 3-Monooxygenase | 1975 |
GABA-like properties of flurazepam and baclofen suggested by rotational behaviour following unilateral intranigral injection: a comparison with the GABA agonist muscimol [proceedings].
Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Baclofen; Behavior; Flurazepam; gamma-Aminobutyric Acid; Humans; Injections; Isoxazoles; Male; Oxazoles; Rats; Stereotyped Behavior; Substantia Nigra | 1977 |
Behavioural evidence for GABAergic activity of the benzodiazepine flurazepam.
Topics: Animals; Anti-Anxiety Agents; Baclofen; Behavior, Animal; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rotation; Substantia Nigra; Synaptic Transmission; Time Factors | 1978 |
Baclofen (beta-p-chlorophenyl-gamma-aminobutyric acid) enhances [3H]gamma-aminobutyric acid (3H-GABA) release from rat globus pallidus in vitro.
Topics: Alanine; Aminobutyrates; Animals; Baclofen; Electric Stimulation; Female; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Neuroglia; Neurons; Potassium; Rats; Time Factors | 1978 |
Which pharmacological action of baclofen matters most?
Topics: Animals; Baclofen; Binding, Competitive; gamma-Aminobutyric Acid | 1979 |
Cardiovascular effects of baclofen in the rat.
Topics: Animals; Baclofen; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Male; Rats; Time Factors | 1979 |
Gabergic compounds and schizophrenia.
Topics: Baclofen; gamma-Aminobutyric Acid; Humans; Schizophrenia; Valproic Acid | 1976 |
Gamma-aminobutyric acid and the search for new anticonvulsant drugs.
Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Aminobutyrates; Animals; Anticonvulsants; Baclofen; Benzodiazepinones; Brain; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Epilepsy; Female; gamma-Aminobutyric Acid; Haplorhini; Humans; Mice; Myoclonus; Papio; Pyrrolidinones | 1978 |
Lioresal in Huntington's disease.
Topics: Aminobutyrates; Baclofen; Dantrolene; Diazepam; Drug Evaluation; Gait; gamma-Aminobutyric Acid; Growth Hormone; Humans; Huntington Disease; Prolactin | 1976 |
Effects of beta-(p-chlorophenyl)-GABA (baclofen) on spinal synaptic activity.
Topics: Action Potentials; Aminobutyrates; Animals; Anura; Baclofen; Drug Interactions; Fenclonine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rana catesbeiana; Rats; Reflex; Reserpine; Spinal Nerve Roots; Synapses; Tetrabenazine; Time Factors | 1977 |
Central GABA receptor agonists: comparison of muscimol and baclofen.
Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P | 1976 |
Possible role of gamma aminobutyric acid (GABA) in the regulation of cAMP system in rat anterior pituitary.
Topics: Aminobutyrates; Animals; Baclofen; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Isoniazid; Isoxazoles; Male; Nipecotic Acids; Pargyline; Picrotoxin; Pituitary Gland, Anterior; Protein Kinases; Rats; Reserpine | 1977 |
The interaction of baclofen (beta-(4-chlorophenyl)Gaba) with GABA systems in rat brain: evidence for a releasing action.
Topics: Aminobutyrates; Animals; Baclofen; Brain; Female; gamma-Aminobutyric Acid; Protein Binding; Rats; Receptors, Neurotransmitter; Synaptosomes | 1978 |
The effect of drugs which alter GABA-ergic function on cerebellar guanosine-3',5'-monophosphate content.
Topics: Animals; Apomorphine; Baclofen; Cerebellum; Cyclic GMP; Drug Interactions; gamma-Aminobutyric Acid; Male; Rats; Time Factors | 1978 |
Baclofen: a selective agonist for a novel type of GABA receptor proceedings.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Mice; Rats; Receptors, Cell Surface | 1979 |
Pharmacology of (+)- and (-)-baclofen: GABA-dependant rotational behaviour and [3H]GABA receptor binding studies.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Rats; Receptors, Neurotransmitter; Stereoisomerism; Substantia Nigra | 1979 |
Baclofen and cerebellar cyclic GMP levels in mice.
Topics: Animals; Arecoline; Baclofen; Cerebellum; Cyclic GMP; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Motor Activity; Pentylenetetrazole; Picrotoxin | 1979 |
Influence of GABA and GABA-like drugs on monoaminergic mechanisms.
Topics: 5-Hydroxytryptophan; Aminobutyrates; Animals; Baclofen; Biogenic Amines; Brain; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Norepinephrine; Rats; Receptors, Drug; Serotonin; Substance P | 1977 |
GABA-induced locomotor activity in the rat, after bilateral injection into the ventral tegmental area.
Topics: Animals; Baclofen; Brain Chemistry; Dopamine; gamma-Aminobutyric Acid; Homovanillic Acid; Injections; Male; Motor Activity; Picrotoxin; Rats; Tegmentum Mesencephali; Time Factors | 1979 |
Baclofen and muscimol: behavioural and neurochemical sequelae of unilateral intranigral administration and effects on 3H-GABA receptor binding.
Topics: Aminobutyrates; Animals; Baclofen; Behavior, Animal; Brain Chemistry; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxydopamines; Injections; Male; Muscimol; Oxazoles; Rats; Receptors, Drug; Substantia Nigra; Time Factors | 1979 |
Effects of the unilateral nigral application of baclofen on dopamine release in the two caudate nuclei of the cat.
Topics: Animals; Baclofen; Cats; Caudate Nucleus; Decerebrate State; Dopamine; Female; gamma-Aminobutyric Acid; Male; Neural Pathways; Substantia Nigra; Time Factors | 1979 |
Evidence that GABA in the nucleus dorsalis raphé induces stimulation of locomotor activity and eating behavior.
Topics: Animals; Baclofen; Brain Chemistry; Brain Stem; Feeding Behavior; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Motor Activity; Muscimol; Raphe Nuclei; Rats; Serotonin; Time Factors | 1979 |
Induction of rotational behaviour by intranigral baclofen suggests possible GABA-agonist activity.
Topics: Aminobutyrates; Animals; Baclofen; Behavior; gamma-Aminobutyric Acid; Humans; Injections; Male; Rats; Stereotyped Behavior; Substantia Nigra | 1977 |
Drug effects in a GABA-dependent rotational behaviour model and on [3H]-GABA receptor binding: studies with the enantiomers of baclofen HCl [proceedings].
Topics: Aminobutyrates; Animals; Baclofen; Behavior; gamma-Aminobutyric Acid; Humans; Male; Rats; Receptors, Drug; Stereoisomerism; Stereotyped Behavior | 1978 |
Modulatory effects of baclofen muscimol and GABA on interspecific aggressive behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Olfactory Bulb; Oxazoles; Rats | 1978 |
Biochemical effects of baclofen (beta-parachlorophenyl-GABA) on the dopamine and the noradrenaline in the rat brain.
Topics: Aminobutyrates; Amphetamines; Animals; Baclofen; Brain; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraperitoneal; Limbic System; Male; Norepinephrine; Rats; Rats, Inbred Strains; Tyrosine | 1977 |
Influence of baclofen and GABA-minetic agents on spontaneous and olfactory-bulb-ablation-induced muricidal behaviour in the rat.
Topics: Aggression; Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Olfactory Bulb; Rats | 1978 |
Dopamine concentrations in the rat brain following injections into the substantia nigra of baclofen, gamma-aminobutyric acid, gamma-hydroxybutyric acid, apomorphine and amphetamine.
Topics: Animals; Apomorphine; Baclofen; Behavior, Animal; Brain Chemistry; Dextroamphetamine; Dopamine; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections; Male; Rats; Substantia Nigra; Time Factors | 1978 |
Baclofen enhances [3h]-GABA release from rat globus pallidus in vitro [proceedings].
Topics: Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Rats | 1978 |
Action of beta-(4-chlorophenyl-GABA) on uptake and metabolism of GABA in different subcellular fractions of rat brain.
Topics: Aminobutyrates; Animals; Baclofen; Biological Transport; Depression, Chemical; gamma-Aminobutyric Acid; Kinetics; Male; Mesencephalon; Rats; Synaptosomes | 1978 |
Convulsions induced by hyperbaric oxygen: inhibition by phenobarbital, diazepam and baclofen.
Topics: Aminobutyrates; Animals; Baclofen; Diazepam; Female; gamma-Aminobutyric Acid; Glycine; Hyperbaric Oxygenation; Isoniazid; Male; Mice; Phenobarbital; Rats; Seizures; Strychnine | 1977 |
Regulation of the mesocortical dopamine neurons.
Topics: 4-Butyrolactone; Acetylcholine; Aminooxyacetic Acid; Baclofen; Cerebral Cortex; Dopamine; gamma-Aminobutyric Acid; Isoxazoles; Neurons; Pimozide; Pyrrolidinones; Sulpiride | 1977 |
[Lioresal in the treatment of spasticity].
Topics: Adolescent; Adult; Aged; Aminobutyrates; Baclofen; Drug Evaluation; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Spasticity; Spinal Cord Injuries | 1976 |
Effects of aminooxyacetic acid and baclofen on the catalepsy and on the increase of mesolimbic and striatal dopamine turnover induced by haloperidol in rats.
Topics: Acetates; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Brain Chemistry; Catalepsy; Corpus Striatum; Dopamine; Female; gamma-Aminobutyric Acid; Haloperidol; Homovanillic Acid; Humans; Limbic System; Rats; Tyrosine | 1976 |
Suppression of ethanol-induced locomotor stimulation by GABA-like drugs.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Brain; Dihydroxyphenylalanine; Ethanol; Female; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Mice; Motor Activity; Rats | 1976 |
Further investigations into the effects of baclofen (Lioresal) on the isolated spinal cord.
Topics: Acetylcholine; Aminobutyrates; Animals; Anura; Baclofen; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Rana temporaria; Spinal Cord | 1975 |
Cellular mechanisms underlying cholinergic and noradrenergic modulation of neuronal firing mode in the cat and guinea pig dorsal lateral geniculate nucleus.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Cats; Choline; Electric Conductivity; Female; gamma-Aminobutyric Acid; Geniculate Bodies; GTP-Binding Proteins; Guinea Pigs; Interneurons; Male; Neurons; Norepinephrine; Potassium; Prazosin; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Scopolamine | 1992 |
Inhibitory role of gamma-amino-butyric acid in the rabbit urinary bladder.
Topics: Animals; Baclofen; Bicuculline; Carbachol; Depression, Chemical; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Rabbits; Receptors, GABA-A; Urinary Bladder | 1992 |
Modulation of extracellular gamma-aminobutyric acid in the ventral pallidum using in vivo microdialysis.
Topics: Animals; Baclofen; Calcium Channels; Dialysis; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; Globus Pallidus; Magnesium Chloride; Male; Muscimol; Neurons; Potassium; Rats; Rats, Inbred Strains; Sodium Channels; Tetrodotoxin; Verapamil; Veratridine | 1992 |
Involvement of intrathalamic GABAB neurotransmission in the control of absence seizures in the rat.
Topics: Animals; Baclofen; Electroencephalography; Epilepsy, Absence; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission; Thalamus; Time Factors | 1992 |
Immunocytochemical visualization of L-baclofen-sensitive GABAB binding sites in the medial vestibular nucleus.
Topics: Animals; Antibodies, Monoclonal; Baclofen; Dendrites; gamma-Aminobutyric Acid; Haplorhini; Microscopy, Immunoelectron; Rats; Receptors, GABA-A; Synapses; Vestibular Nuclei | 1992 |
Functionally distinct subpopulations of striatal neurons are differentially regulated by GABAergic and dopaminergic inputs--I. In vivo analysis.
Topics: Animals; Baclofen; Benzazepines; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Male; Neural Pathways; Neurons; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-A; Sulpiride; Sympathectomy, Chemical | 1992 |
The mechanism of GABAB-mediated slowing of the activation phase of high voltage-activated Ca2+ channels in rat sensory neurons.
Topics: Animals; Baclofen; Calcium Channels; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Ganglia, Spinal; Neurons, Afferent; Rats; Receptors, GABA-A | 1992 |
Changes in the effect of gamma-aminobutyric acid on prolactin secretion during sexual maturation in female rats.
Topics: 4-Aminobutyrate Transaminase; Aging; Aminooxyacetic Acid; Animals; Baclofen; Female; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Maturation | 1992 |
Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study.
Topics: Afferent Pathways; Animals; Baclofen; Biological Transport; Dendrites; Dialysis; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Interneurons; Kinetics; Male; Models, Neurological; Morphine; Muscimol; Naloxone; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tegmentum Mesencephali; Time Factors | 1992 |
Estrogen suppresses mu-opioid- and GABAB-mediated hyperpolarization of hypothalamic arcuate neurons.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; beta-Endorphin; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estradiol; Evoked Potentials; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Membrane Potentials; Neurons; Ovariectomy; Receptors, Opioid; Receptors, Opioid, mu; Tetrodotoxin | 1992 |
Physiological role of GABAb receptors in the mammalian neostriatum.
Topics: Animals; Baclofen; Corpus Striatum; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1992 |
Pharmacological characterization of GABAB-mediated responses in the CA1 region of the rat hippocampal slice.
Topics: Animals; Baclofen; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Organophosphorus Compounds; Picrotoxin; Rats; Receptors, GABA-A | 1992 |
On the inhibitory actions of baclofen and gamma-aminobutyric acid in rat ventral midbrain culture.
Topics: Animals; Baclofen; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Membrane Potentials; Mesencephalon; Neurons; Potassium; Rats; Receptors, GABA-A; Synapses; Tetrodotoxin | 1992 |
Stimulation of high affinity gamma-aminobutyric acidB receptors potentiates the depolarization-induced increase of intraneuronal ionized calcium content in cerebellar granule neurons.
Topics: Animals; Baclofen; Calcium; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dantrolene; Drug Interactions; Egtazic Acid; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Intracellular Fluid; Membrane Potentials; Neurons; Organophosphorus Compounds; Potassium Channels; Rats; Receptors, GABA-A; Stimulation, Chemical | 1992 |
Blockade by (-)baclofen of recurrent inhibition in the guinea pig dentate gyrus in vitro.
Topics: Animals; Baclofen; Bicuculline; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Neural Inhibition; Neurons; Receptors, GABA-A | 1992 |
Age-dependent changes in substantia nigra GABA-mediated seizure suppression.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Dominance, Cerebral; Energy Metabolism; Flurothyl; gamma-Aminobutyric Acid; Muscimol; Rats; Receptors, GABA-A; Seizures; Status Epilepticus; Stereotyped Behavior; Substantia Nigra; Synaptic Transmission | 1992 |
GABA, acting at both GABAA and GABAB receptors, inhibits the release of cholecystokinin-like material from the rat spinal cord in vitro.
Topics: Animals; Baclofen; Cholecystokinin; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Perfusion; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord | 1992 |
Inhibitory responses of rat basolateral amygdaloid neurons recorded in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amygdala; Animals; Baclofen; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Histocytochemistry; In Vitro Techniques; Isoquinolines; Male; Membrane Potentials; Neurons; Picrotoxin; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereotyped Behavior | 1992 |
GABAergic involvement in the acquisition of voluntary ethanol intake in laboratory rats.
Topics: Alcohol Drinking; Animals; Baclofen; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoxazoles; Male; Rats; Receptors, GABA-A | 1992 |
Differing actions of beta-(2-thienyl)-gamma-aminobutyric acid in central and peripheral preparations.
Topics: Animals; Baclofen; Brain; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Receptors, GABA-A; Structure-Activity Relationship; Thiophenes | 1992 |
Granule cell inhibition and the activity of hilar neurons.
Topics: 4-Aminopyridine; Animals; Axons; Baclofen; Dendrites; Evoked Potentials; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Neural Inhibition; Neural Pathways; Neurons; Picrotoxin; Potassium Channels; Receptors, GABA-A; Synapses | 1992 |
GABA-induced responses in Purkinje cell dendrites of the rabbit cerebellar slice.
Topics: Animals; Baclofen; Calcium; Cerebellum; Dendrites; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Purkinje Cells; Rabbits; Receptors, GABA-A | 1992 |
Changes in ligand binding to GABAA receptor sites in pacific salmon (Oncorhynchus) brain during spawning migration and "aging".
Topics: Aging; Aminobutyrates; Analgesics; Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Female; gamma-Aminobutyric Acid; Isoxazoles; Kinetics; Ligands; Male; Muscimol; Receptors, GABA-A; Salmon; Sexual Behavior, Animal | 1992 |
Participation of GABAergic systems in the production of antinociception by various stresses in mice.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Stress, Psychological | 1992 |
Actions of 4-amino-3-(5-methoxybenzo(b)furan-2-yl) butanoic acid and 4-amino-3-benzo(b)furan-2-yl butanoic acid in the rat spinal cord.
Topics: Analgesics; Animals; Baclofen; Benzofurans; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1992 |
Modulation by GABAB receptors of spontaneous synchronous activities induced by 4-aminopyridine in the rat hippocampus.
Topics: 4-Aminopyridine; Animals; Baclofen; Dose-Response Relationship, Drug; Epilepsy; Evoked Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1992 |
Differential action of (-)-baclofen on the primary afferent depolarization produced by segmental and descending inputs.
Topics: Anesthesia; Animals; Baclofen; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Interneurons; Nerve Fibers; Neuromuscular Depolarizing Agents; Neurons, Afferent; Picrotoxin; Receptors, GABA-A; Reticular Formation; Skin; Spinal Cord; Synapses | 1992 |
Changes in gamma-aminobutyric acid release induced by topical administration of drugs affecting its metabolism and receptors: studies in freely moving guinea pigs with epidural cups.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Baclofen; beta-Alanine; Calcium; Cerebral Cortex; Epidural Space; Ethanolamines; Feedback; Female; gamma-Aminobutyric Acid; Guinea Pigs; Kinetics; Male; Nipecotic Acids; Norepinephrine; Receptors, GABA-A; Sodium; Tetrodotoxin | 1992 |
Presynaptic modulation by GABAB receptors of glutamatergic excitation and GABAergic inhibition of neostriatal neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Corpus Callosum; Corpus Striatum; Electric Stimulation; Evoked Potentials; Feedback; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1992 |
Presynaptic GABAB receptor activation attenuates synaptic transmission to rat sympathetic preganglionic neurons in vitro.
Topics: Animals; Autonomic Fibers, Preganglionic; Baclofen; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sympathetic Nervous System; Synapses; Synaptic Transmission; Synaptosomes | 1992 |
Functional evidence for multiple gamma-aminobutyric acidB receptor subtypes in the rat cerebral cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Chromatography, High Pressure Liquid; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Organophosphorus Compounds; Peptides; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
GABAergic influences on somatostatin secretion from hypothalamic neurons cultured in defined medium.
Topics: Animals; Baclofen; Bicuculline; Cells, Cultured; Culture Media; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Muscimol; Neurons; Nipecotic Acids; Rats; Receptors, GABA-A; Somatostatin | 1992 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of luteinizing hormone-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Gonadotropin-Releasing Hormone; In Vitro Techniques; Male; Median Eminence; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
GABAergic synaptic transmission in projections from the basal forebrain and hippocampal formation to the amygdala: an in vivo iontophoretic study.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Baclofen; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Male; Neural Pathways; Prosencephalon; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Receptors, Neurotransmitter; Synapses; Synaptic Transmission | 1992 |
Systemic administration of baclofen and the GABAB antagonist, CGP 35348, does not affect GABA, glutamate or aspartate in microdialysates of the striatum of conscious rats.
Topics: Animals; Aspartic Acid; Baclofen; Corpus Striatum; Dialysis; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Organophosphorus Compounds; Potassium; Rats; Rats, Inbred Strains | 1992 |
Effects of inhaled alpha 2-adrenoceptor and GABAB receptor agonists on citric acid-induced cough and tidal volume changes in guinea pigs.
Topics: Acetylcholine; Administration, Inhalation; Adrenergic alpha-Agonists; Animals; Atropine; Azepines; Baclofen; Citrates; Citric Acid; Cough; gamma-Aminobutyric Acid; Guinea Pigs; Male; Receptors, GABA-A; Respiration; Tidal Volume; Xylazine; Yohimbine | 1992 |
Age-dependent regulation of GABAA receptors in neocortex.
Topics: Aging; Animals; Baclofen; Cats; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Muscimol; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Veratridine | 1992 |
Dissociation of mu and delta opioid receptor-mediated reductions in evoked and spontaneous synaptic inhibition in the rat hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Axons; Baclofen; Bicuculline; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Synapses | 1992 |
Activation of phosphoinositide turnover and protein kinase C by neurotransmitters that modulate calcium channels in embryonic chick sensory neurons.
Topics: Animals; Baclofen; Calcium Channels; Cell Membrane; Chick Embryo; gamma-Aminobutyric Acid; GTP-Binding Proteins; Neurons, Afferent; Neurotransmitter Agents; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Protein Kinase C; Virulence Factors, Bordetella | 1992 |
gamma-Aminobutyric acid, through GABAA receptors, inhibits the potassium-stimulated release of calcitonin gene-related peptide- but not that of substance P-like material from rat spinal cord slices.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P | 1992 |
Serotonin-GABA treatment is hypothesized for self-injury in Lesch-Nyhan syndrome.
Topics: Baclofen; Drug Therapy, Combination; gamma-Aminobutyric Acid; Humans; Kynurenine; Lesch-Nyhan Syndrome; Male; Self-Injurious Behavior; Serotonin | 1992 |
GABAergic and cholinergic mediation in the antinociceptive action of homotaurine.
Topics: Acetates; Acetic Acid; Analgesics; Animals; Baclofen; gamma-Aminobutyric Acid; Immersion; Male; Mice; Pain; Pain Measurement; Parasympathetic Nervous System; Reaction Time; Scopolamine; Taurine | 1992 |
Baclofen reverses the hypersensitivity of dorsal horn wide dynamic range neurons to mechanical stimulation after transient spinal cord ischemia; implications for a tonic GABAergic inhibitory control of myelinated fiber input.
Topics: Animals; Baclofen; Decerebrate State; Electric Stimulation; gamma-Aminobutyric Acid; Ischemia; Muscimol; Nerve Fibers; Nerve Fibers, Myelinated; Neurons; Physical Stimulation; Rats; Rats, Inbred Strains; Spinal Cord | 1992 |
Influence of GABA on gonadotrophin release in the goldfish.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Brain; Estradiol; gamma-Aminobutyric Acid; Goldfish; Gonadotropins, Pituitary; Hypothalamus; Immunohistochemistry; Muscimol; Pituitary Gland; Seasons; Telencephalon; Testosterone; Vigabatrin | 1992 |
Tonic activity of rat medial vestibular nucleus neurones in vitro and its inhibition by GABA.
Topics: Action Potentials; Animals; Baclofen; Cobalt; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neurons; Nipecotic Acids; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Vestibular Nuclei | 1992 |
Alterations in the properties of hippocampal pyramidal neurons in the aged rat.
Topics: Acetylcholine; Action Potentials; Aging; Analysis of Variance; Animals; Baclofen; Carbachol; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Learning; Male; Membrane Potentials; Nerve Endings; Neurons; Pyramidal Tracts; Rats; Rats, Inbred Strains; Regression Analysis; Synapses; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1992 |
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.
Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Chloroquine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Phenobarbital; Seizures | 1992 |
GABA agonists and omega conotoxin GVIA modulate responses to nerve activation of the perfused rat mesentery.
Topics: Animals; Baclofen; Calcium Channels; Electric Stimulation; gamma-Aminobutyric Acid; Male; Mesenteric Arteries; Muscimol; omega-Conotoxin GVIA; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sympathetic Nervous System; Vasoconstriction; Vasodilation | 1991 |
GABAA and GABAB receptor-mediated effects on the spontaneous activity of the longitudinal layer in cat terminal ileum.
Topics: Animals; Baclofen; Bicuculline; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1991 |
Depolarizing actions of GABA and glycine on amphibian retinal horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Cobalt; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kynurenine; Lithium; Neuromuscular Depolarizing Agents; Nicotinic Acids; Picrotoxin; Receptors, GABA-A; Retina; Urodela | 1991 |
Opioid and prostaglandin mechanisms involved in the effects of GABAergic drugs on body temperature.
Topics: Animals; Baclofen; Bicuculline; Body Temperature; Dose-Response Relationship, Drug; Endorphins; gamma-Aminobutyric Acid; Indomethacin; Injections, Intraperitoneal; Muscimol; Naloxone; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Changes in extracellular K+ evoked by GABA, THIP and baclofen in the guinea-pig hippocampal slice.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Electrodes; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Isoxazoles; Nipecotic Acids; Potassium; Proline; Receptors, GABA-A; Temperature | 1991 |
Inhibition of calcium influx and calcium current by gamma-aminobutyric acid in single synaptic terminals.
Topics: Animals; Baclofen; Calcium; Calcium Channels; Electric Conductivity; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons; Picrotoxin; Retina; Synapses | 1991 |
Role of dopamine and GABA in the control of motor activity elicited from the rat nucleus accumbens.
Topics: Animals; Baclofen; Dopamine; Dopamine Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Motor Activity; Nucleus Accumbens; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, GABA-A; Sesterterpenes; Taurine | 1991 |
Effects of GABA and related agents on the electrical activity of hypothalamic ventromedial nucleus neurons in vitro.
Topics: Animals; Baclofen; Bicuculline; Electrophysiology; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Ventromedial Hypothalamic Nucleus | 1991 |
GABAergic drugs and conflict behavior in the rat: lack of similarities with the actions of benzodiazepines.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Behavior, Animal; Benzodiazepines; Bicuculline; Brain; Conflict, Psychological; Drug Interactions; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Nicotinic Acids; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission | 1991 |
(-)-baclofen and gamma-aminobutyric acid inhibit calcium currents in isolated retinal ganglion cells.
Topics: Animals; Baclofen; Bicuculline; Calcium; Calcium Channels; Cobalt; gamma-Aminobutyric Acid; Goldfish; In Vitro Techniques; Kinetics; Receptors, GABA-A; Retinal Ganglion Cells; Time Factors | 1991 |
The involvement of GABAB receptors and coupled G-proteins in spinal GABAergic presynaptic inhibition.
Topics: Animals; Baclofen; Electrophysiology; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Lampreys; Neural Inhibition; Neurons; Pertussis Toxin; Receptors, GABA-A; Spinal Cord; Synapses; Synaptic Transmission; Virulence Factors, Bordetella | 1991 |
Gamma-aminobutyric acidA (GABAA) receptor modulation of morphine inhibition of norepinephrine release.
Topics: Animals; Baclofen; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1991 |
Subpopulations of GABA-mediated synaptic potentials in slices of rat dorsal striatum are differentially modulated by presynaptic GABAB receptors.
Topics: Animals; Baclofen; Caudate Nucleus; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Organophosphorus Compounds; Putamen; Rats; Receptors, GABA-A; Synaptic Membranes | 1991 |
Baclofen and carbamazepine in supraspinal spasticity.
Topics: Administration, Oral; Adult; Baclofen; Brain Injuries; Carbamazepine; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Muscle Spasticity; Parasympatholytics; Quadriplegia; Receptors, GABA-A | 1991 |
Pertussis-toxin-sensitive inhibition by (-) baclofen of Ca signals in bovine chromaffin cells.
Topics: Animals; Baclofen; Bicuculline; Calcium; Cattle; Cells, Cultured; Chromaffin System; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Pertussis Toxin; Receptors, GABA-A; Virulence Factors, Bordetella | 1991 |
Sexual maturation modifies the GABAergic control of gonadotrophin secretion in female rats.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Female; Follicle Stimulating Hormone; gamma-Aminobutyric Acid; Gonadotropins; Luteinizing Hormone; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Maturation | 1991 |
GABA/BZ-and NMDA-receptor interaction in digoxin-induced convulsions in rats.
Topics: Animals; Baclofen; Diazepam; Digoxin; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Salts; Seizures | 1991 |
Noradrenaline release in the rat vena cava is inhibited by gamma-aminobutyric acid via GABAB receptors but not affected by histamine.
Topics: Animals; Baclofen; Bicuculline; Corticosterone; Desipramine; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; In Vitro Techniques; Male; Muscimol; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vena Cava, Inferior; Yohimbine | 1991 |
Phaclofen-reversible effects of GABA in the spinal cord of the rat.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Injections, Spinal; Lidocaine; Male; Rats; Rats, Inbred Strains; Spinal Cord; Stereoisomerism; Sympathetic Nervous System | 1991 |
Serotonin modulates muscimol- and baclofen-elicited inhibition of cerebellar Purkinje cells.
Topics: Action Potentials; Animals; Baclofen; Cerebellum; gamma-Aminobutyric Acid; Glycine; Male; Muscimol; Purkinje Cells; Rats; Receptors, GABA-A; Serotonin | 1991 |
The modulation of rat hippocampal synaptic conductances by baclofen and gamma-aminobutyric acid.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Rats; Receptors, GABA-A; Receptors, Neurotransmitter | 1991 |
Involvement of GABA systems in feedback regulation of glutamate-and GABA-mediated synaptic potentials in rat neostriatum.
Topics: Animals; Baclofen; Corpus Striatum; Electric Stimulation; Electrophysiology; Evoked Potentials; Feedback; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1991 |
Effects of GABAergic and noradrenergic injections into the cerebellar flocculus on vestibulo-ocular reflexes in the rabbit.
Topics: Adaptation, Physiological; Animals; Baclofen; Cerebellum; Female; gamma-Aminobutyric Acid; Isoproterenol; Male; Muscimol; Norepinephrine; Purkinje Cells; Rabbits; Receptors, GABA-A; Reflex, Vestibulo-Ocular; Sotalol; Vestibule, Labyrinth | 1991 |
[The action of GABA agonists and an antagonist on the frequency structure of the electrical activity of different brain formations in rats].
Topics: Animals; Baclofen; Bicuculline; Brain; Electrodes, Implanted; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Wakefulness | 1991 |
Postnatal maturation of the GABAergic system in rat neocortex.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Cerebral Cortex; Chlorides; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains | 1991 |
Synaptic physiology of horizontal connections in the cat's visual cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Lidocaine; Receptors, GABA-A; Synapses; Visual Cortex | 1991 |
Synaptic responses of guinea pig cingulate cortical neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; Epilepsy; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guinea Pigs; Gyrus Cinguli; Magnesium; Neurons; Quinoxalines; Synapses | 1991 |
Baclofen and adenosine inhibit synaptic potentials mediated by gamma-aminobutyric acid and glutamate release in rat nucleus accumbens.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Nucleus Accumbens; Phenylisopropyladenosine; Quinoxalines; Rats; Receptors, GABA-A; Receptors, Purinergic; Synapses | 1991 |
Synaptic responses of guinea pig and rat central amygdala neurons in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine; Amino Acids; Amygdala; Animals; Baclofen; Electric Stimulation; Electrodes; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Guinea Pigs; In Vitro Techniques; Male; Neuromuscular Depolarizing Agents; Neurons; Quinoxalines; Rats; Rats, Inbred Strains; Synapses | 1991 |
Some pharmacological differences between hippocampal excitatory and inhibitory synapses in transmitter release: an in vitro study.
Topics: Adenosine; Animals; Baclofen; Carbachol; Electrophysiology; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membranes; Neurotransmitter Agents; Pregnancy; Rats; Synapses | 1991 |
Glycinergic control of [Leu5]enkephalin levels in chicken retina.
Topics: Animals; Baclofen; Chickens; Enkephalin, Leucine; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Isoxazoles; Muscimol; Neurotransmitter Agents; Picrotoxin; Radioimmunoassay; Retina; Strychnine | 1991 |
Inhibitory transmission in the basolateral amygdala.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Baclofen; Bicuculline; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Pentobarbital; Potassium; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1991 |
Gamma-aminobutyric acid (GABAB) receptor-mediated inhibition of tyrosine hydroxylase activity in the striatum of rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Calcium; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; gamma-Aminobutyric Acid; Hydrazines; In Vitro Techniques; Male; Muscimol; Neural Pathways; Picrotoxin; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Tyrosine 3-Monooxygenase | 1991 |
gamma-Aminobutyric acidB receptors mediate inhibition of somatostatin release from cerebrocortex nerve terminals.
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Nerve Endings; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Somatostatin; Synaptosomes | 1991 |
GABAB receptor stimulation by baclofen and taurine enhances excitatory amino acid induced phosphatidylinositol turnover in neonatal rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Baclofen; Calcium; Cerebellum; gamma-Aminobutyric Acid; N-Methylaspartate; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Receptors, GABA-A; Taurine | 1991 |
GABA affects the glutamate receptor-chloride channel complex in mechanically isolated and internally perfused Aplysia neurons.
Topics: Animals; Anura; Aplysia; Baclofen; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channels; Muscimol; Neurons; Perfusion; Receptors, Glutamate; Receptors, Neurotransmitter | 1990 |
Pharmacological evidence indicating a role of GABAergic systems in termination of limbic seizures.
Topics: Animals; Baclofen; Bicuculline; Chloride Channels; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Limbic System; Male; Membrane Proteins; Muscimol; Neural Inhibition; Picrotoxin; Rats; Seizures | 1990 |
Expression of mammalian gamma-aminobutyric acid receptors with distinct pharmacology in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Cattle; Cerebral Cortex; Electric Conductivity; gamma-Aminobutyric Acid; Gene Expression; Membrane Potentials; Oocytes; Pentobarbital; Picrotoxin; Poly A; Rats; Receptors, GABA-A; Retina; RNA; RNA, Messenger; Transfection; Xenopus | 1991 |
GABAB receptor modulation of the release of substance P from capsaicin-sensitive neurones in the rat trachea in vitro.
Topics: Animals; Baclofen; Bicuculline; Capsaicin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neurons; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substance P; Taurine; Trachea | 1991 |
Voltage-dependent calcium currents in dissociated granule cells from rat cerebellum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Baclofen; Bicuculline; Calcium Channels; Cerebellum; Electrophysiology; gamma-Aminobutyric Acid; Membrane Potentials; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Regulation of cardiovascular sympathetic neurons by substance P and gamma-aminobutyric acid in the rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Capsaicin; Cardiovascular Physiological Phenomena; Cardiovascular System; Catecholamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Heart Rate; Injections, Spinal; Male; Muscimol; Neurons; Neuropeptide Y; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Substance P; Sympathetic Nervous System | 1991 |
A simple and multi-purpose "concentration-clamp" method for rapid superfusion.
Topics: Animals; Baclofen; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Ion Channels; Micromanipulation; Neurons; Perfusion; Potassium; Rats; Temperature | 1991 |
Increased intracellular gamma-aminobutyric acid selectively lowers the level of the larger of two glutamate decarboxylase proteins in cultured GABAergic neurons from rat cerebral cortex.
Topics: 4-Aminobutyrate Transaminase; Amino Acids; Aminocaproates; Animals; Baclofen; Cells, Cultured; Cerebral Cortex; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunoblotting; Intracellular Membranes; Muscimol; Neurons; Rats; Vigabatrin | 1992 |
Bicuculline- and baclofen-insensitive gamma-aminobutyric acid binding to rat cerebellar membranes.
Topics: Animals; Baclofen; Bicuculline; Binding Sites; Calcium; Cerebellum; gamma-Aminobutyric Acid; Isonicotinic Acids; Kinetics; Male; Membranes; Rats; Rats, Inbred Strains | 1992 |
Failure of the gamma-aminobutyric acid (GABA) derivative, baclofen, to stimulate growth hormone secretion in Parkinson's disease.
Topics: Aged; Baclofen; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Middle Aged; Parkinson Disease; Reference Values | 1991 |
Anoxic block of GABAergic IPSPs.
Topics: Action Potentials; Animals; Baclofen; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Oxygen; Rats; Rats, Inbred Strains; Synapses | 1991 |
Action of gamma-aminobutyric acid (GABA) in the isolated photosensory pineal organ.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Kinetics; Light; Muscimol; Neurons; Photic Stimulation; Picrotoxin; Pineal Gland; Time Factors; Trout | 1991 |
Coexistence of gamma-aminobutyric acid type A and type B receptors in testicular interstitial cells.
Topics: Ammonium Chloride; Animals; Baclofen; Binding Sites; Detergents; gamma-Aminobutyric Acid; Male; Octoxynol; Polyethylene Glycols; Rats; Rats, Inbred Strains; Receptors, GABA-A; Testis; Testosterone | 1991 |
Differential effects of chronic antidepressants in behavioural tests of beta-adrenergic and GABAB receptor function.
Topics: Albuterol; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Monoamine Oxidase Inhibitors; Motor Activity; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
GABAergic-serotonergic interactions in regulating lordosis.
Topics: 5,7-Dihydroxytryptamine; Animals; Baclofen; Estradiol; Female; gamma-Aminobutyric Acid; Hypothalamus; Male; Mesencephalon; Norepinephrine; Ovariectomy; Pargyline; Posture; Preoptic Area; Progesterone; Rats; Rats, Inbred Strains; Serotonin; Sexual Behavior, Animal | 1991 |
Differential effects of baclofen and gamma-aminobutyric acid (GABA) on rat piriform cortex pyramidal neurons in vitro.
Topics: Animals; Baclofen; Electrophysiology; gamma-Aminobutyric Acid; Male; Neural Inhibition; Olfactory Bulb; Olfactory Pathways; Rats; Receptors, GABA-A | 1990 |
gamma-Aminobutyric acid inhibits the potassium-stimulated release of somatostatin from rat spinal cord slices.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Morphine; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Somatostatin; Spinal Cord | 1990 |
Acid secretagogue mechanisms of a GABA-mimetic (PCPGABA) in the anesthetized rat: effects of hypothermia.
Topics: Animals; Baclofen; Bethanechol; Bethanechol Compounds; Body Temperature; Body Temperature Regulation; Deoxyglucose; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Histamine; Male; Rats; Rats, Inbred Strains | 1990 |
Somatostatin depresses GABA receptor-mediated inhibition in the rat dorsolateral septal nucleus.
Topics: Animals; Baclofen; Brain; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Kinetics; Male; Membrane Potentials; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Somatostatin; Synapses; Time Factors | 1990 |
Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Baclofen; Bicuculline; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Piperazines; Rats; Receptors, GABA-A; Suprachiasmatic Nucleus | 1990 |
GABA-induced potassium channels in cultured neurons.
Topics: Animals; Animals, Newborn; Baclofen; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Neurons; Potassium Channels; Rats; Receptors, GABA-A | 1990 |
A comparison of the effect of calcium channel ligands and GABAB agonists and antagonists on transmitter release and somatic calcium channel currents in cultured neurons.
Topics: Animals; Baclofen; Calcium Channel Agonists; Calcium Channels; Cells, Cultured; Cerebellum; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamates; Glutamic Acid; Neurons; Neurotransmitter Agents; Nicotinic Acids; Oxadiazoles; Stereoisomerism; Virulence Factors, Bordetella | 1990 |
GABAA and GABAB antagonists prevent the opioid inhibition of endogenous acetylcholine release evoked by glutamate from rat neostriatal slices.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Morphine; Narcotics; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
GABA mediated inhibition of abdominal postural flexion in lobster.
Topics: Abdomen; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Ganglia; Interneurons; Muscimol; Nephropidae; Physical Stimulation; Picrotoxin; Posture; Reflex | 1991 |
Cholinergic nerve terminals of human cerebral cortex possess a GABA transporter whose activation induces release of acetylcholine.
Topics: Acetylcholine; Anticonvulsants; Baclofen; Bicuculline; Biotransformation; Carrier Proteins; Cerebral Cortex; Choline; Female; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Membrane Proteins; Membrane Transport Proteins; Middle Aged; Muscimol; Nerve Endings; Nerve Tissue Proteins; Nipecotic Acids; Organic Anion Transporters; Parasympathetic Nervous System; Proline; Synaptosomes | 1991 |
Spinal 5-HT3 receptor-mediated antinociception: possible release of GABA.
Topics: Analgesia; Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; N-Methylaspartate; Neurons; Nociceptors; Pain Measurement; Picrotoxin; Receptors, Serotonin; Serotonin; Spinal Cord | 1991 |
GABAergic mechanisms in morphine-induced hypothermia.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Animals; Baclofen; Body Temperature; Female; Flumazenil; gamma-Aminobutyric Acid; Male; Morphine; Rats; Rats, Inbred Strains | 1990 |
Neuroleptic-induced "painful legs and moving toes" syndrome: successful treatment with clonazepam and baclofen.
Topics: Baclofen; Causalgia; Clonazepam; Dyskinesia, Drug-Induced; Female; gamma-Aminobutyric Acid; Humans; Leg; Middle Aged; Molindone; Schizophrenia; Serotonin; Syndrome; Toes | 1990 |
Action of baclofen, GABA and antagonists on the membrane potential of cultured astrocytes of rat spinal cord.
Topics: Animals; Astrocytes; Autoradiography; Baclofen; Bicuculline; Electrophysiology; Female; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Microelectrodes; Muscimol; Organophosphorus Compounds; Pregnancy; Rats; Spinal Cord | 1990 |
Role of gamma-aminobutyric acid in the zona incerta in the control of luteinizing hormone release and ovulation.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Diencephalon; Estradiol; Female; GABA Antagonists; gamma-Aminobutyric Acid; Luteinizing Hormone; Muscimol; Ovariectomy; Ovulation; Proestrus; Progesterone; Rats; Rats, Inbred Strains | 1990 |
Functional coupling of the gamma-aminobutyric acidB receptor with calcium ion channel and GTP-binding protein and its alteration following solubilization of the gamma-aminobutyric acidB receptor.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; Calcium Channels; Cattle; Cerebral Cortex; gamma-Aminobutyric Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanine Nucleotides; Kinetics; Pertussis Toxin; Receptors, GABA-A; Solubility; Synaptic Membranes; Virulence Factors, Bordetella | 1990 |
GABA terminal autoreceptors in the pars compacta and in the pars reticulata of the rat substantia nigra are GABAB.
Topics: Animals; Anticonvulsants; Baclofen; gamma-Aminobutyric Acid; Male; Muscimol; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Synaptosomes; Tritium | 1990 |
Central GABAA excitatory and GABAB inhibitory receptors regulate gastric acid secretion in rats.
Topics: Anesthesia; Animals; Baclofen; Bicuculline; Central Nervous System; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gastric Acid; Injections, Intraventricular; Male; Muscimol; Pylorus; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Stimulation of luteinizing hormone release by gamma-aminobutyric acid (GABA) agonists: mediation by GABAA-type receptors and activation of chloride and voltage-sensitive calcium channels.
Topics: Amino Acid Sequence; Animals; Baclofen; Calcium Channels; Cells, Cultured; Chloride Channels; Chlorides; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Isoxazoles; Luteinizing Hormone; Membrane Proteins; Molecular Sequence Data; Muscimol; Nifedipine; Pituitary Gland, Anterior; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
An analysis of anticonvulsant actions of GABA agonists (progabide and baclofen) in the kindling model of epilepsy.
Topics: Animals; Anticonvulsants; Baclofen; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
A subset of local interneurons generate slow inhibitory postsynaptic potentials in hippocampal neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Baclofen; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Interneurons; Neural Inhibition; Rats; Receptors, GABA-A | 1990 |
Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study.
Topics: Animals; Autoradiography; Baclofen; Binding, Competitive; Brain; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Inhibition of baclofen binding to rat cerebellar membranes by phaclofen, saclofen, 3-aminopropylphosphonic acid and related GABAB receptor antagonists.
Topics: Animals; Baclofen; Cerebellum; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Propylamines; Rats; Rats, Inbred Strains | 1990 |
GABAB receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Decerebrate State; Electric Stimulation; gamma-Aminobutyric Acid; Male; Muscimol; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A; Taurine; Tubocurarine; Vascular Resistance | 1990 |
Characterization of GABAergic seizure regulation in the midline thalamus.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Epilepsy; Female; Flurazepam; gamma-Aminobutyric Acid; Pentobarbital; Pentylenetetrazole; Piperidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thalamic Nuclei | 1990 |
Gamma-aminobutyric acid-A and -B receptor antagonists increase luteinizing hormone-releasing hormone neuronal responsiveness to intracerebroventricular norepinephrine in ovariectomized estrogen-treated rats.
Topics: Animals; Baclofen; Bicuculline; Estradiol; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Luteinizing Hormone; Neurons; Norepinephrine; Ovariectomy; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Evidence for GABAB-receptors on cultured astrocytes of rat CNS: autoradiographic binding studies.
Topics: Animals; Astrocytes; Baclofen; Brain Stem; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Rats; Receptors, GABA-A; Spinal Cord | 1990 |
Paired-pulse depression of monosynaptic GABA-mediated inhibitory postsynaptic responses in rat hippocampus.
Topics: Action Potentials; Animals; Baclofen; Female; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Picrotoxin; Rats; Synapses; Synaptic Transmission; Tetrodotoxin | 1990 |
Evidence for functionally distinct subclasses of gamma-aminobutyric acid receptors in rabbit retina.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Cell Fractionation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Light; Models, Theoretical; Pentobarbital; Picrotoxin; Rabbits; Receptors, GABA-A; Retina | 1990 |
GABAB receptor-mediated contractile effects resistant to tetrodotoxin in isolated cat ileum.
Topics: Animals; Baclofen; Bicuculline; Cats; Drug Resistance; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Receptors, GABA-A; Tetrodotoxin | 1990 |
Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Diazepam; Dibenzazepines; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Neurons; Pentobarbital; Picrotoxin; Receptors, GABA-A; Snails | 1990 |
Solubilization and partial purification of GABAB receptor from bovine brain.
Topics: Animals; Baclofen; Binding, Competitive; Cattle; Cerebral Cortex; Chromatography, Affinity; gamma-Aminobutyric Acid; Kinetics; Receptors, GABA-A; Solubility; Synaptic Membranes | 1990 |
Chronic antidepressant drug treatment does not affect GH response to baclofen in depressed subjects.
Topics: Adult; Amitriptyline; Baclofen; Depressive Disorder; Drug Interactions; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hypothalamus; Male; Middle Aged; Receptors, GABA-A; Secretory Rate; Stimulation, Chemical; Up-Regulation | 1990 |
Are GABAB receptors involved in the pharmacological effects of ethanol?
Topics: Animals; Baclofen; Cells, Cultured; Chlorine; Diazepam; Ethanol; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Picrotoxin; Radioisotopes; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Spinal Cord | 1990 |
Neurochemical correlates of gamma-aminobutyrate (GABA) inhibition in cat visual cortex.
Topics: Animals; Baclofen; Calcium; Cats; Cell Membrane; Female; GABA Antagonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoxazoles; Male; Neurons; Potassium; Pyridazines; Receptors, GABA-A; Visual Cortex | 1990 |
GABA, depression and the mechanism of action of antidepressant drugs: a neuroendocrine approach.
Topics: Adult; Amitriptyline; Antidepressive Agents; Baclofen; Brain; Depressive Disorder; Fluoxetine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Imipramine; Male; Middle Aged; Personality Tests; Receptors, GABA-A | 1990 |
Involvement of GABA receptors in the regulation of neurite growth in cultured embryonic chick tectum.
Topics: Animals; Axons; Baclofen; Cells, Cultured; Chick Embryo; Culture Media; gamma-Aminobutyric Acid; Isoxazoles; Ligands; Muscimol; Receptors, GABA-A; Superior Colliculi | 1990 |
Potentiation of gamma-aminobutyric acid-mediated inhibition by isoproterenol in the cerebellar cortex: receptor specificity.
Topics: Action Potentials; Animals; Baclofen; Cerebellar Cortex; Drug Synergism; gamma-Aminobutyric Acid; Isonicotinic Acids; Isoproterenol; Male; Neurons; Purkinje Cells; Rats; Rats, Inbred F344; Receptors, GABA-A | 1990 |
GABAA receptor-mediated stimulation of non-adrenergic non-cholinergic neurones in the dog ileocolonic junction.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Dogs; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurons; Nitroglycerin; Receptors, GABA-A; Taurine; Tetrodotoxin | 1990 |
Endogenous GABA acts on GABAB receptors in nucleus tractus solitarius to increase blood pressure.
Topics: 4-Aminobutyrate Transaminase; Aminocaproates; Animals; Baclofen; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vigabatrin | 1990 |
[The depressing effect of GABA on synaptic excitation in isolated rat hippocampal slices].
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neural Inhibition; Neurons; Penicillin G Benzathine; Picrotoxin; Rats; Receptors, Neurotransmitter; Synapses | 1990 |
Properties of GABA-activated whole-cell currents in bipolar cells of the rat retina.
Topics: Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Membrane Potentials; Muscimol; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Retina | 1990 |
Presynaptic glutamate receptors depress excitatory monosynaptic transmission between mouse hippocampal neurones.
Topics: Action Potentials; Aminobutyrates; Animals; Baclofen; Cells, Cultured; gamma-Aminobutyric Acid; Glutamates; Hippocampus; Kainic Acid; Mice; Quisqualic Acid; Receptors, Glutamate; Receptors, Neurotransmitter; Synaptic Transmission | 1990 |
GABA(B)-related activity involved in synaptic processing of somatosensory information in S1 cortex of the anaesthetized cat.
Topics: Anesthesia; Animals; Baclofen; Bicuculline; Cats; Electric Stimulation; Electrodes; Female; gamma-Aminobutyric Acid; Iontophoresis; Isoxazoles; Male; Muscimol; Neurons; Physical Stimulation; Somatosensory Cortex; Synapses | 1990 |
Presynaptic effects of gamma-aminobutyric acid on norepinephrine release and uptake in rat pineal gland.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Muscimol; Norepinephrine; Pineal Gland; Rats; Rats, Inbred Strains | 1990 |
Serotonin attenuates a slow inhibitory postsynaptic potential in rat hippocampal neurons.
Topics: 4-Aminopyridine; 5,7-Dihydroxytryptamine; Administration, Topical; Animals; Baclofen; Electric Conductivity; Electrophysiology; Fenfluramine; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Neurons; Rats; Rats, Inbred Strains; Serotonin; Synapses | 1990 |
Myorelaxant effect of baclofen injected to the nucleus accumbens septi.
Topics: Animals; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Haloperidol; Injections, Intraperitoneal; Male; Microinjections; Midazolam; Muscimol; Muscle Relaxation; Nicardipine; Nucleus Accumbens; Rats; Rats, Inbred Strains; Task Performance and Analysis | 1990 |
[Ulcerogenic effect of a GABA derivative, baclofen, in the rat: effect of hypothermia].
Topics: Animals; Baclofen; Duodenal Ulcer; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Hypothermia; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
GABAB agonists modulate a transient potassium current in cultured mammalian hippocampal neurons.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Baclofen; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Neurons; Potassium Channels; Rats | 1990 |
Endogenous GABA mediates presynaptic inhibition of spontaneous and evoked excitatory synaptic potentials in the rat neostriatum.
Topics: Animals; Baclofen; Corpus Striatum; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Synapses; Tetrodotoxin | 1990 |
Bicuculline and picrotoxin block phase advances induced by GABA agonists in the circadian rhythm of locomotor activity in the golden hamster by a phaclofen-insensitive mechanism.
Topics: Animals; Baclofen; Bicuculline; Circadian Rhythm; Cricetinae; gamma-Aminobutyric Acid; Male; Mesocricetus; Microinjections; Motor Activity; Muscimol; Picrotoxin; Stereotaxic Techniques; Triazolam | 1990 |
Effects of excitatory and inhibitory amino acid agonists and antagonists of ventral horn cells in slices of spinal cord isolated from adult rats.
Topics: Action Potentials; Amino Acids; Animals; Anterior Horn Cells; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Strychnine; Synapses | 1990 |
Effects of GABA antagonists and structural GABA analogues on baclofen stimulated gastric acid secretion in the rat.
Topics: Amino Acids; Anesthesia; Animals; Baclofen; Bethanechol Compounds; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Gastric Acid; Male; Rats; Rats, Inbred Strains | 1990 |
Differing actions of baclofen and 3-amino-propylphosphinic acid in rat neocortical slices.
Topics: Animals; Baclofen; Cerebral Cortex; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1990 |
Differences in the effects (in vitro) of ethylenediamine on the guinea-pig and rat intestine.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Ethylenediamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Intestine, Small; Jejunum; Male; Muscle Relaxation; Muscle, Smooth; Rats; Rats, Inbred Strains | 1990 |
On the presynaptic action of baclofen at inhibitory synapses between cultured rat hippocampal neurones.
Topics: Action Potentials; Animals; Baclofen; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Neurons; Pertussis Toxin; Rats; Synapses; Virulence Factors, Bordetella | 1990 |
Phaclofen inhibition of the slow inhibitory postsynaptic potential in hippocampal slice cultures: a possible role for the GABAB-mediated inhibitory postsynaptic potential.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Organ Culture Techniques; Rats | 1990 |
Some characteristics of baclofen-evoked responses of primary afferents in frog spinal cord.
Topics: 4-Aminopyridine; Action Potentials; Animals; Baclofen; Barium; gamma-Aminobutyric Acid; In Vitro Techniques; Neurons, Afferent; Potassium; Rana pipiens; Spinal Cord; Tetrodotoxin | 1990 |
Inhibition by gamma-amino-n-butyric acid and baclofen of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Gastric Mucosa; Male; Methylnitronitrosoguanidine; Rats; Rats, Inbred Strains; Reference Values; Stomach Neoplasms | 1990 |
Direct evidence indicating that a GABA-mimetic stimulates acid secretion through central mechanisms.
Topics: Anesthesia; Animals; Baclofen; Brain; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Hypothalamus, Middle; Injections; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains | 1990 |
Stimulatory effect of some therapeutic drugs used for improving cerebral insufficiency on gastric acid secretion in rats.
Topics: Animals; Atropine; Baclofen; Carbachol; Cerebrovascular Disorders; Cytidine Diphosphate Choline; gamma-Aminobutyric Acid; Gastric Acid; Male; Pantothenic Acid; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach | 1990 |
gamma-Aminobutyric acid-induced depression of calcium currents of chick sensory neurons.
Topics: Animals; Baclofen; Calcium; Cell Membrane Permeability; Chick Embryo; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials | 1985 |
Central effects of baclofen on the L-dopa induced hyperactive urinary bladder of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Injections, Intraventricular; Levodopa; Male; Naloxone; Rats; Rats, Inbred Strains; Substance P; Urinary Bladder | 1985 |
Effects of gamma-aminobutyric acid and (-)-baclofen on calcium and potassium currents in cat dorsal root ganglion neurones in vitro.
Topics: Animals; Baclofen; Cats; Electrodes; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Ion Channels; Neurons | 1986 |
gamma-Aminobutyric acid (GABA) causes consistent depolarization of neurons in the guinea pig supraoptic nucleus due to an absence of GABAB recognition sites.
Topics: Animals; Baclofen; Chlorides; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Hypothalamus; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neurons; Receptors, GABA-A; Supraoptic Nucleus | 1987 |
Calcium dependence of baclofen- and GABA-induced depression of responses to transmural stimulation in the guinea-pig isolated ileum.
Topics: Animals; Baclofen; Calcium; Electric Stimulation; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Muscle, Smooth; Ruthenium Red | 1987 |
Low concentrations of GABA reduce accommodation in primary afferent neurons by an action at GABAB receptors.
Topics: Animals; Baclofen; Calcium; Female; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Male; Neural Conduction; Neurons, Afferent; Rats; Receptors, GABA-A | 1987 |
GABAergic modulation of a substance P-mediated reflex of slow time course in the isolated rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Substance P | 1987 |
Effect of various GABA-receptor agonists and antagonists on anaphylactic histamine release in the guinea-pig ileum.
Topics: Anaphylaxis; Animals; Baclofen; beta-Alanine; Depression, Chemical; gamma-Aminobutyric Acid; Guinea Pigs; Histamine Release; Ileum; Isonicotinic Acids; Male; Muscle, Smooth; Receptors, GABA-A; Taurine | 1987 |
Contrasting properties of K+ conductances induced by baclofen and gamma-aminobutyric acid in slices of the guinea pig hippocampus.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Potentials; Picrotoxin; Potassium; Reference Values | 1987 |
Modulation of non-adrenergic, non-cholinergic neural bronchoconstriction in guinea-pig airways via GABAB-receptors.
Topics: Animals; Atropine; Autonomic Nervous System; Baclofen; Bicuculline; Blood Pressure; Bronchi; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Propranolol; Receptors, GABA-A; Substance P; Time Factors; Vagus Nerve | 1989 |
Involvement of a pertussis toxin-sensitive G-protein in the pharmacological properties of septo-hippocampal neurones.
Topics: Animals; Baclofen; Carbachol; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Male; Neurons; Pertussis Toxin; Rats; Rats, Inbred Strains; Serotonin; Virulence Factors, Bordetella | 1989 |
GABAergic agents-induced antinociceptive effect in mice.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; gamma-Aminobutyric Acid; Male; Mice; Morphine; Muscimol; Pain; Picrotoxin; Rats; Rats, Inbred Strains; Reaction Time; Sensory Thresholds; Valproic Acid | 1989 |
Effect of guanosine 5'-O-(3-thiotriphosphate) and calcium on gamma-aminobutyric acidB binding as a function of postnatal development.
Topics: Animals; Baclofen; Brain; Calcium; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Mathematics; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thionucleotides | 1989 |
Release-regulating autoreceptors of the GABAB-type in human cerebral cortex.
Topics: Aged; Aminooxyacetic Acid; Anticonvulsants; Baclofen; Cerebral Cortex; Female; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Male; Middle Aged; Muscimol; Nipecotic Acids; Receptors, GABA-A; Synaptosomes | 1989 |
Activity-dependent disinhibition. III. Desensitization and GABAB receptor-mediated presynaptic inhibition in the hippocampus in vitro.
Topics: Animals; Baclofen; Cells, Cultured; gamma-Aminobutyric Acid; Hippocampus; Iontophoresis; Membrane Potentials; Muscimol; Neural Inhibition; Rats; Receptors, GABA-A | 1989 |
GABAB-receptor-mediated actions of baclofen in rat isolated neocortical slice preparations: antagonism by phosphono-analogues of GABA.
Topics: Animals; Baclofen; Cerebral Cortex; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Propylamines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
GABAA receptor-mediated positive inotropism in guinea-pig isolated left atria: evidence for the involvement of capsaicin-sensitive nerves.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Muscimol; Myocardial Contraction; Neurons; Neuropeptides; Receptors, GABA-A; Taurine | 1989 |
Cardiovascular responses elicited by gamma-aminobutyric acid in the nucleus tractus solitarius: evidence for action at the GABAB receptor.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Hemodynamics; Injections; Male; Medulla Oblongata; Nipecotic Acids; Proline; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vasopressins | 1989 |
Different gamma-aminobutyric acid receptor subtypes are involved in the regulation of opiate-dependent and independent luteinizing hormone-releasing hormone secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; Baclofen; Bicuculline; Dinoprostone; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Male; Median Eminence; Muscimol; Naloxone; Narcotics; Oxytocin; Phentolamine; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
gamma-Aminobutyric acidB receptor activation modifies agonist binding to beta-adrenergic receptors in rat brain cerebral cortex.
Topics: Animals; Baclofen; Binding, Competitive; Cell Membrane; Cerebral Cortex; gamma-Aminobutyric Acid; Isoproterenol; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, GABA-A | 1989 |
Release of gamma-[3H]aminobutyric acid (GABA) from electrically stimulated rat cortical slices and its modulation by GABAB autoreceptors.
Topics: Animals; Baclofen; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tetrodotoxin | 1989 |
GABAA receptors in the rat stomach may mediate mucoprotective effects.
Topics: Administration, Oral; Aminooxyacetic Acid; Animals; Anti-Ulcer Agents; Baclofen; Bicuculline; Binding, Competitive; Ethanol; gamma-Aminobutyric Acid; Gastric Mucosa; Ligands; Muscimol; Rats; Receptors, GABA-A; Stomach Ulcer; Vagotomy; Valproic Acid | 1989 |
GABA regulation of circadian responses to light. I. Involvement of GABAA-benzodiazepine and GABAB receptors.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Circadian Rhythm; Cricetinae; GABA Antagonists; gamma-Aminobutyric Acid; Light; Male; Mesocricetus; Receptors, GABA-A | 1989 |
gamma-Aminobutyric acid inhibits the release of alpha-melanocyte-stimulating hormone from rat hypothalamic slices.
Topics: alpha-MSH; Aminooxyacetic Acid; Animals; Baclofen; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains | 1989 |
GABAergic drugs and lordosis behavior in the female rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Estradiol; Female; gamma-Aminobutyric Acid; Isoxazoles; Oxazoles; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal; Taurine | 1989 |
Central- and peripheral-type benzodiazepine receptors: similar regulation by stress and GABA receptor agonists.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Benzodiazepinones; Binding Sites; Brain; Flunitrazepam; gamma-Aminobutyric Acid; Kidney; Male; Mice; Muscimol; Myocardium; Rats; Receptors, GABA-A; Stress, Physiological | 1989 |
The modulation by chlormethiazole of the GABAA-receptor complex in rat brain.
Topics: Animals; Baclofen; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlormethiazole; CLC-2 Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Picrotoxin; Rats; Receptors, GABA-A | 1989 |
GABAB receptors are up-regulated by chronic treatment with lithium or carbamazepine. GABA hypothesis of affective disorders?
Topics: Animals; Baclofen; Carbamazepine; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Lithium; Male; Mood Disorders; Muscimol; Rats; Rats, Inbred WKY; Receptors, GABA-A; Synaptic Membranes | 1989 |
Stimulation by phaclofen of inositol 1,4,5-triphosphate production in cultured neurons from chick tectum.
Topics: Animals; Baclofen; Chick Embryo; gamma-Aminobutyric Acid; Inosine Nucleotides; Inosine Triphosphate; Isoxazoles; Neurons; Receptors, GABA-A; Superior Colliculi | 1989 |
L-type calcium channels in the regulation of neurite outgrowth from rat dorsal root ganglion neurons in culture.
Topics: 2-Chloroadenosine; Animals; Animals, Newborn; Axons; Baclofen; Bradykinin; Calcium Channels; Cells, Cultured; gamma-Aminobutyric Acid; Ganglia, Spinal; Neurons; Potassium; Rats; Veratridine | 1989 |
Release of endogenous GABA from the substantia nigra is not controlled by GABA autoreceptors.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Nipecotic Acids; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra; Tetrodotoxin | 1989 |
GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABAA-type agonist recognition site.
Topics: Animals; Ascaris; Baclofen; Binding, Competitive; Dieldrin; Electric Stimulation; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Muscles; Pentobarbital; Receptors, GABA-A; Stereoisomerism | 1989 |
An in vitro study of the relationship between GABA receptor function and propulsive motility in the distal colon of the rabbit.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Autonomic Nervous System; Baclofen; Colon; gamma-Aminobutyric Acid; Gastrointestinal Motility; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Rabbits; Receptors, GABA-A; Sesterterpenes; Taurine | 1989 |
A novel type of GABA receptor in rat spinal cord?
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Synaptosomes | 1989 |
Antagonism at GABAB receptors by saclofen and related sulphonic analogues of baclofen and GABA.
Topics: Animals; Baclofen; Cerebral Cortex; Evoked Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Receptors, GABA-A | 1989 |
[The electrical activity of the hippocampus in rats centrally administered GABA agonists and antagonists].
Topics: Animals; Baclofen; Bicuculline; Drug Interactions; Electrodes, Implanted; Electroencephalography; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Modulation of striatal serotonin metabolism by baclofen, a gamma-aminobutyric acidB receptor agonist.
Topics: Animals; Baclofen; Corpus Striatum; gamma-Aminobutyric Acid; Hippocampus; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin | 1989 |
Late inhibitory postsynaptic potentials in rat prefrontal cortex may be mediated by GABAB receptors.
Topics: Animals; Baclofen; Electric Conductivity; Electric Stimulation; Evoked Potentials; Frontal Lobe; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Isoxazoles; Male; Membrane Potentials; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Synapses | 1989 |
gamma-Aminobutyric acid (GABA)-induced currents of skate Muller (glial) cells are mediated by neuronal-like GABAA receptors.
Topics: Animals; Baclofen; Bicuculline; Cells, Cultured; Electric Conductivity; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Membrane Potentials; Muscimol; Neuroglia; Neurons; Receptors, GABA-A; Skates, Fish | 1989 |
GABA as an inhibitory neurotransmitter in human cerebral cortex.
Topics: Baclofen; Cerebral Cortex; Chlorides; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Injections; Intracellular Membranes; Muscimol; Neural Inhibition; Neurons; Neurotransmitter Agents | 1989 |
Decreased gamma-aminobutyric acid (GABA) modulatory effect on rat vas deferens neurotransmission after chronic administration of imipramine.
Topics: Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Humans; Imipramine; Isoproterenol; Male; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Vas Deferens | 1989 |
GABAB receptor modulation of adenylate cyclase activity in rat brain slices.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Baclofen; Brain; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; gamma-Aminobutyric Acid; In Vitro Techniques; Nipecotic Acids; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
GABAergic agents and clonidine attenuate footshock-induced aggression in mice.
Topics: Aggression; Animals; Baclofen; Clonidine; Diazepam; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Reserpine | 1989 |
Augmentation of glutamate responses by GABA in the rat's motorcortex in vivo.
Topics: Animals; Aspartic Acid; Baclofen; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Motor Cortex; Muscimol; N-Methylaspartate; Oxadiazoles; Quisqualic Acid; Rats | 1989 |
Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids.
Topics: Action Potentials; Animals; Baclofen; Dopamine; Electric Stimulation; Electrophysiology; gamma-Aminobutyric Acid; Intracellular Membranes; Narcotics; Neurons; Rats; Reaction Time; Substantia Nigra | 1989 |
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1989 |
GABAergic modulation of acetylcholine release in cholinergic synaptosomes from Torpedo marmorata electric organ.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Muscimol; Potassium; Synaptosomes; Torpedo | 1989 |
Inhibitory effect of GABA on cerebrovascular sympathetic neurotransmission.
Topics: Adrenergic Fibers; Animals; Baclofen; Cerebral Arteries; Cerebrovascular Circulation; Electric Stimulation; Female; gamma-Aminobutyric Acid; Goats; Isometric Contraction; Neural Inhibition; Norepinephrine; Picrotoxin; Vasoconstriction | 1989 |
Baclofen antagonism by 4-amino-3-(5-methoxybenzo[b]furan-2-yl) butanoic acid in the cat spinal cord.
Topics: Animals; Baclofen; Benzofurans; Cats; Electric Stimulation; gamma-Aminobutyric Acid; Interneurons; Neurons, Afferent; Reflex, Monosynaptic; Spinal Cord | 1989 |
Effect of GABA (gamma-aminobutyric acid) on neurotransmission in inferior colliculus slices from the guinea pig.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Chlorides; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Inferior Colliculi; Muscimol; Neural Inhibition | 1989 |
Rhythmical bursting activity and GABAergic mechanisms in the medial septum of normal and pertussis toxin-pretreated rats.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Male; Neurons; Nipecotic Acids; Pertussis Toxin; Proline; Rats; Rats, Inbred Strains; Septum Pellucidum; Virulence Factors, Bordetella | 1989 |
Baclofen and phaclofen modulate GABA release from slices of rat cerebral cortex and spinal cord but not from retina.
Topics: Amino Acids; Aminocaproates; Aminolevulinic Acid; Animals; Baclofen; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Retina; Spinal Cord; Vigabatrin | 1989 |
Carbachol reduces IK,baclofen, but not IK,GABA in guinea pig hippocampal slices.
Topics: Animals; Baclofen; Carbachol; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Membrane Potentials; Neurons | 1989 |
Modulation of calcium uptake and D-aspartate release by GABAB receptors in cultured cerebellar granule cells.
Topics: Animals; Aspartic Acid; Baclofen; Calcimycin; Calcium; Calcium Radioisotopes; Cells, Cultured; Cerebellum; gamma-Aminobutyric Acid; Muscimol; Nimodipine; Rats; Receptors, GABA-A | 1987 |
Cortisol: a potent biphasic modulator at GABAA-receptor complexes in the guinea pig isolated ileum.
Topics: Animals; Baclofen; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Ileum; In Vitro Techniques; Male; Muscle Contraction; Receptors, GABA-A; Taurine | 1987 |
Studies on [3H]GABA and endogenous GABA release in rat cerebral cortex suggest the presence of autoreceptors of the GABAB type.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Median Eminence; Nipecotic Acids; Picrotoxin; Potassium; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1987 |
A physiological role for GABAB receptors in the central nervous system.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Potassium; Rats; Receptors, GABA-A; Serotonin; Synapses | 1988 |
Inhibition of neuronal membrane GABAB receptor binding by GABA structural analogues.
Topics: 4-Aminobutyrate Transaminase; Alanine; Amino Acids; Amino Acids, Cyclic; Amino Acids, Neutral; Animals; Baclofen; Binding, Competitive; Brain; Cell Membrane; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Neurons; Receptors, GABA-A | 1988 |
(-)-Baclofen activates presynaptic GABAB receptors on GABAergic inhibitory neurons from embryonic rat hippocampus.
Topics: Action Potentials; Animals; Baclofen; Cells, Cultured; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Neural Inhibition; Rats; Receptors, GABA-A | 1988 |
Effect of GABA on basal and vagally mediated gastric acid secretion and hormone release in dogs.
Topics: Animals; Baclofen; Blood Glucose; Dogs; gamma-Aminobutyric Acid; Gastric Acid; Gastric Fistula; Gastrins; Gastrointestinal Hormones; Insulin; Male; Receptors, GABA-A; Vagus Nerve | 1988 |
Sensitivity of embryonic spontaneous motility to the GABA agonists baclofen and muscimol.
Topics: Animals; Baclofen; Chick Embryo; gamma-Aminobutyric Acid; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors | 1988 |
Potential involvement of a baclofen-sensitive autoreceptor in the modulation of the release of endogenous GABA from rat brain slices in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain; Cerebral Cortex; Corpus Striatum; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1988 |
Presynaptic modulation of the release of GABA by GABAA receptors in pars compacta and by GABAB receptors in pars reticulata of the rat substantia nigra.
Topics: Animals; Baclofen; Bicuculline; Brain; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1988 |
GABAB receptor-mediated inhibition of histamine H1-receptor-induced inositol phosphate formation in slices of rat cerebral cortex.
Topics: Animals; Baclofen; Carbachol; Cerebral Cortex; gamma-Aminobutyric Acid; Histamine; Inositol; Inositol Phosphates; Isonicotinic Acids; Kinetics; Lithium; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Histamine H1; Sugar Phosphates | 1988 |
GABAA and GABAB sites in bovine adrenal medulla membranes.
Topics: Adrenal Medulla; Animals; Baclofen; Binding Sites; Calcium; Cattle; Cell Membrane; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Muscimol; Receptors, GABA-A | 1988 |
Decreased response to GABA-B agonists in longitudinal smooth muscle-myenteric plexus preparations from morphine-tolerant guinea-pigs.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Drug Tolerance; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; Male; Morphine; Muscle, Smooth; Receptors, GABA-A | 1988 |
Influence of GABA, baclofen and bicuculline on the extracellular K+ activity in the olfactory bulb of the developing rat.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Olfactory Bulb; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Phaclofen antagonizes baclofen-induced suppression of visually evoked responses in the cat's striate cortex.
Topics: Animals; Baclofen; Cats; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Receptors, GABA-A; Visual Cortex | 1988 |
Release-regulating GABAA receptors are present on noradrenergic nerve terminals in selective areas of the rat brain.
Topics: Animals; Baclofen; Brain; Cerebral Cortex; gamma-Aminobutyric Acid; Hippocampus; Hypothalamus; Male; Muscimol; Nerve Endings; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Synaptosomes | 1987 |
GABAA-receptor-mediated inhibition of the delayed increase in intragastric pressure to stimulation of vagal afferent fibres in cats.
Topics: Animals; Baclofen; Cats; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Male; Muscimol; Muscle Contraction; Neurons, Afferent; Pressure; Receptors, GABA-A; Stomach; Vagus Nerve | 1988 |
GABA-ergic mechanisms in the anticonvulsive activity of newly synthesized barbiturates. II. Correlation of HB-7 with GABA-ergic agents.
Topics: Animals; Anticonvulsants; Baclofen; Barbiturates; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Muscimol; Pentobarbital; Receptors, GABA-A | 1988 |
Paradoxical antagonism by bicuculline of the inhibition by baclofen of the electrically evoked release of [3H]GABA from rat cerebral cortex slices.
Topics: Animals; Baclofen; Bicuculline; Cerebral Cortex; Electric Stimulation; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stereoisomerism | 1988 |
Classification of GABA receptors in snail neurones.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Membrane Potentials; Muscimol; Neurons; Receptors, GABA-A; Snails | 1988 |
Modulation of GABAergic neurotransmission in the brain by dipeptides.
Topics: Animals; Baclofen; Brain; Chlorides; Dipeptides; gamma-Aminobutyric Acid; Mice; Mice, Inbred Strains; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission; Synaptosomes | 1988 |
Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Catalepsy; Dronabinol; Drug Synergism; Flumazenil; Flupenthixol; Flurazepam; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Nipecotic Acids; Receptors, GABA-A; Strychnine; Taurine; Tiagabine | 1988 |
Inhibition of sexual reflexes by lumbosacral injection of a GABAB agonist in the male rat.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Injections, Spinal; Isoxazoles; Lumbosacral Region; Male; Penile Erection; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal; Spinal Cord | 1988 |
Excitatory and inhibitory action of GABA on synaptic transmission in slices of guinea pig superior colliculus.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Muscimol; Nipecotic Acids; Perfusion; Proline; Receptors, GABA-A; Superior Colliculi; Synaptic Membranes; Synaptic Transmission | 1988 |
Two inhibitory postsynaptic potentials, and GABAA and GABAB receptor-mediated responses in neocortex of rat and cat.
Topics: Action Potentials; Animals; Baclofen; Barium; Bicuculline; Cats; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neurons; Picrotoxin; Rats; Receptors, GABA-A; Somatosensory Cortex; Synapses; Time Factors; Visual Cortex | 1988 |
The non-GABAergic nature of 3H-baclofen binding in rat peripheral tissues.
Topics: Animals; Baclofen; Binding, Competitive; Calcium Chloride; Cations; gamma-Aminobutyric Acid; Kidney; Liver; Male; Neurotransmitter Agents; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, GABA-A; Spleen | 1985 |
Baclofen inhibits the spontaneous and visually evoked responses of neurones in the striate cortex of the cat.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Cats; Depression, Chemical; Evoked Potentials, Visual; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Receptors, GABA-A; Visual Cortex | 1987 |
Kindling-induced changes in EEG recorded during stimulation from the site of stimulation. III. Direct pharmacological manipulations of the kindled amygdala.
Topics: 2-Amino-5-phosphonovalerate; Amygdala; Animals; Atropine; Baclofen; Diazepam; Electroencephalography; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Neural Inhibition; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Valine | 1987 |
Primary afferent terminal excitability in the normal and spastic mutant mouse spinal cord.
Topics: Animals; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Bicuculline; Electric Stimulation; gamma-Aminobutyric Acid; Glutamates; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Muscle Spasticity; Nerve Endings; Neurons, Afferent; Spinal Cord | 1987 |
gamma-Aminobutyric acid-induced modulation of acetylcholine release from the guinea pig lung.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Calcium; Dose-Response Relationship, Drug; Female; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Lung; Male; Muscimol; Tetrodotoxin | 1987 |
GABA binding in bovine adrenal medulla membranes is sensitive to baclofen.
Topics: Adrenal Medulla; Animals; Baclofen; Bicuculline; Cattle; Cell Membrane; gamma-Aminobutyric Acid; Kinetics; Muscimol; Receptors, GABA-A | 1987 |
Regulation of [3H]GABA release from strips of guinea pig urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Bicuculline; Clonazepam; Clonidine; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Pentobarbital; Phenylephrine; Pirenzepine; Potassium; Prazosin; Tritium; Urinary Bladder; Yohimbine | 1988 |
Optic tract stimulation evokes GABAA but not GABAB IPSPs in the rat ventral lateral geniculate nucleus.
Topics: Action Potentials; Animals; Baclofen; gamma-Aminobutyric Acid; Geniculate Bodies; In Vitro Techniques; Male; Neural Inhibition; Rats; Rats, Inbred Strains; Visual Pathways | 1989 |
Cholinergic and GABAergic regulation of dopamine beta-hydroxylase activity in the adrenal gland of the rat.
Topics: 5,7-Dihydroxytryptamine; Acetylcholine; Adrenal Glands; Aminocaproates; Animals; Baclofen; Bicuculline; Dopamine beta-Hydroxylase; Enzyme Induction; Fenclonine; gamma-Aminobutyric Acid; Hydroxydopamines; Male; Muscimol; Oxotremorine; Propranolol; Rats; Vigabatrin | 1986 |
Neonatal treatment with monoamine uptake inhibitors alters later response in behavioural 'despair' test to beta and GABA-B receptor agonists.
Topics: Albuterol; Animals; Animals, Newborn; Antidepressive Agents; Baclofen; Behavior, Animal; Desipramine; gamma-Aminobutyric Acid; Male; Nomifensine; Rats; Rats, Inbred Strains; Time Factors; Zimeldine | 1988 |
Characterization of the relationship between gamma-aminobutyric acid B agonists and transmitter-coupled cyclic nucleotide-generating systems in rat brain.
Topics: Adenosine; Adenosine Deaminase; Animals; Baclofen; Brain; Cyclic AMP; gamma-Aminobutyric Acid; Histamine; In Vitro Techniques; Isoproterenol; Kinetics; Male; Norepinephrine; Organ Specificity; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1985 |
Modulation of acetylcholine release from rat striatal slices by the GABA/benzodiazepine receptor complex.
Topics: Acetylcholine; Animals; Atropine; Baclofen; Benzodiazepinones; Clonazepam; Corpus Striatum; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Haloperidol; In Vitro Techniques; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures.
Topics: Animals; Baclofen; Calcium; Cells, Cultured; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Potassium; Rats; Receptors, GABA-A | 1985 |
GABAA and GABAB receptors in detrusor strips from guinea-pig bladder dome.
Topics: Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Interactions between naloxone and GABA in the control of locomotor activity in the rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Brain; gamma-Aminobutyric Acid; Male; Motor Activity; Naloxone; Neural Inhibition; Rats; Rats, Inbred Strains; Synaptic Transmission | 1985 |
Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Baclofen; Cerebral Cortex; Dihydroalprenolol; gamma-Aminobutyric Acid; Hippocampus; Humans; Imipramine; Isoxazoles; Kinetics; Male; Mice; Mood Disorders; Nomifensine; Receptors, Adrenergic; Receptors, GABA-A | 1985 |
Autoreceptors regulate gamma-[3H]aminobutyric acid release from the guinea pig small intestine.
Topics: Animals; Baclofen; Bicuculline; Female; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Muscimol; Myenteric Plexus; Potassium; Receptors, GABA-A; Tetrodotoxin | 1985 |
Inhibitory effect of GABA on sympathetic neurotransmission in rabbit ear artery.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Arteries; Baclofen; Ear, External; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Norepinephrine; Picrotoxin; Potassium; Rabbits; Sympathetic Nervous System; Synaptic Transmission; Taurine; Vasoconstriction | 1985 |
Modulatory activity of GABAB receptors on cholinergic tone in guinea-pig distal colon.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Bicuculline; Blood Pressure; Colon; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Male; Parasympathetic Nervous System; Picrotoxin; Receptors, GABA-A | 1985 |
Specific [3H]gamma-aminobutyric acid binding to vestibular membranes of the chick inner ear.
Topics: Animals; Baclofen; Bicuculline; Binding, Competitive; Chickens; gamma-Aminobutyric Acid; Male; Muscimol; Receptors, GABA-A; Subcellular Fractions; Vestibule, Labyrinth | 1985 |
gamma-Aminobutyric acidA (GABAA) receptors modulate [3H]GABA release from isolated neuronal growth cones in the rat.
Topics: Animals; Animals, Newborn; Axons; Azides; Baclofen; Benzamides; Bicuculline; Brain; Dendrites; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Homeostasis; Muscimol; Potassium; Rats; Receptors, GABA-A; Stimulation, Chemical; Subcellular Fractions; Tritium | 1985 |
GABAergic drugs and sexual behaviour in the male rat.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sexual Behavior, Animal | 1985 |
Dual effect of GABA on the contractile activity of the guinea-pig isolated urinary bladder.
Topics: Acetylcholine; Animals; Baclofen; Dimethylphenylpiperazinium Iodide; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1985 |
Existence of sites for anions and divalent cations in the solubilized gamma-aminobutyric acid/benzodiazepine receptor complex.
Topics: Animals; Anions; Baclofen; Brain; Calcium Chloride; Cations, Divalent; Cattle; Cobalt; Flunitrazepam; gamma-Aminobutyric Acid; Hot Temperature; Magnesium; Magnesium Chloride; Receptors, GABA-A; Sodium Chloride; Zinc | 1985 |
Antagonistic effect of delta-aminovaleric acid on bicuculline-insensitive gamma-aminobutyric acid B (GABA B) sites in the rat's brain.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Bicuculline; Binding, Competitive; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Pre- and postsynaptic effects of baclofen in the rat hippocampal slice.
Topics: Animals; Baclofen; Calcium; Dose-Response Relationship, Drug; Electric Conductivity; gamma-Aminobutyric Acid; Hippocampus; Male; Potassium; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission | 1985 |
GABAergic effects of reserpine following chronic treatment.
Topics: Animals; Baclofen; Binding, Competitive; Cerebral Cortex; Dihydroalprenolol; gamma-Aminobutyric Acid; Hippocampus; Imipramine; Isoxazoles; Male; Mice; Receptors, GABA-A; Reserpine | 1985 |
D-Baclofen is an antagonist at baclofen receptors mediating antinociception in the spinal cord.
Topics: Alkynes; Aminobutyrates; Aminocaproates; Analgesics; Animals; Baclofen; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Morphine; Norepinephrine; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 1985 |
GABA-noradrenergic interaction: evidence for differential sites of action for GABA-A and GABA-B receptors.
Topics: Adrenergic Fibers; Animals; Baclofen; Benzylamines; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Norepinephrine; Receptors, GABA-A | 1985 |
Further behavioral analysis of GABA-mediated inhibition in the early chick embryo.
Topics: Animals; Baclofen; Bradykinin; Brain; Chick Embryo; gamma-Aminobutyric Acid; Histamine; Motor Activity; Serotonin; Stereoisomerism; Synaptic Transmission | 1986 |
GABAB receptors in the rabbit uterus may mediate contractile responses.
Topics: Animals; Atropine; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Phentolamine; Rabbits; Receptors, GABA-A; Tetrodotoxin; Uterine Contraction | 1985 |
Evidence for prejunctional GABAB receptors mediating inhibition of ovarian follicle contraction induced by nerve stimulation.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cattle; Electric Stimulation; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Ovarian Follicle; Phentolamine; Receptors, GABA-A; Synaptic Membranes; Taurine; Tetrodotoxin | 1986 |
The postganglionic excitatory innervation of the mouse urinary bladder and its modulation by prejunctional GABAB receptors.
Topics: Animals; Atropine; Baclofen; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Hemicholinium 3; In Vitro Techniques; Male; Mice; Muscle Contraction; Physostigmine; Receptors, Cell Surface; Receptors, GABA-A; Urinary Bladder | 1986 |
The effect of presynaptic receptor stimulation on adenosine 3',5'-cyclic monophosphate concentrations in rat cortical synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Baclofen; Cerebral Cortex; Clonidine; Cyclic AMP; gamma-Aminobutyric Acid; Male; Norepinephrine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Synaptosomes | 1986 |
GABAB receptor-mediated enhancement of vasoactive intestinal peptide-stimulated cyclic AMP production in slices of rat cerebral cortex.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Bicuculline; Cerebral Cortex; Cyclic AMP; Dose-Response Relationship, Drug; Drug Synergism; gamma-Aminobutyric Acid; Isoxazoles; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vasoactive Intestinal Peptide | 1986 |
Effects of gamma-aminobutyric acid (GABA) receptor agonists on the neurotoxicity and anticonvulsant activity of barbiturates in mice.
Topics: Animals; Anticonvulsants; Baclofen; Barbiturates; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Nervous System; Oxazoles; Receptors, GABA-A; Seizures | 1986 |
gamma-Aminobutyric acid agonists and antagonists alter chloride flux across brain membranes.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Animals; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Isoxazoles; Liver; Male; Mice; Mice, Inbred DBA; Muscimol; Picrotoxin; Receptors, GABA-A; Sodium; Sulfates; Taurine; Temperature | 1986 |
Baclofen suppresses hippocampal epileptiform activity at low concentrations without suppressing synaptic transmission.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Potassium; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses; Synaptic Transmission | 1986 |
GABAA and GABAB receptors on porcine pars intermedia cells in primary culture: functional role in modulating peptide release.
Topics: Animals; Baclofen; Cells, Cultured; gamma-Aminobutyric Acid; Melanocyte-Stimulating Hormones; Membrane Potentials; Neurons; Pituitary Gland; Receptors, GABA-A; Swine | 1986 |
GABA receptor binding in rat cerebral cortex and superior cervical ganglion in the absence of GABAergic synapses.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Binding, Competitive; Cerebral Cortex; Female; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synapses | 1986 |
Effects of GABA agonists on Herxheimer microshock in guinea pigs.
Topics: Anaphylaxis; Animals; Baclofen; Bronchial Spasm; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Receptors, GABA-A; Stereoisomerism | 1986 |
Potent depressant action of baclofen on hippocampal epileptiform activity in vitro: possible use in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Baclofen; Carbamazepine; Diazepam; Epilepsy; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Phenobarbital; Synaptic Transmission | 1986 |
The effects of the GABA-mimetic drugs, progabide and baclofen, on the biochemistry and function of 5-hydroxytryptamine and noradrenaline.
Topics: Animals; Baclofen; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Serotonin; Serotonin; Stereoisomerism | 1986 |
Availability of chemosensory receptors is down-regulated by habituation of larvae to a morphogenetic signal.
Topics: Animals; Baclofen; Chemoreceptor Cells; gamma-Aminobutyric Acid; Larva; Metamorphosis, Biological; Mollusca; Receptors, GABA-A | 1986 |
Comparison of the effect of gamma-aminobutyric acid and its derivative baclofen on the activity of Purkinje cells of frog cerebellum in vitro.
Topics: Action Potentials; Animals; Baclofen; Chlorides; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Purkinje Cells; Rana esculenta; Rana temporaria; Reserpine; Synaptic Transmission | 1986 |
Participation of GABA/benzodiazepine receptor system in the adrenal chromaffin cell function.
Topics: 4-Aminobutyrate Transaminase; Adrenal Medulla; Animals; Baclofen; Bicuculline; Catecholamines; Cattle; Cells, Cultured; Dogs; Enkephalin, Methionine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Muscimol; Rats; Receptors, GABA-A; Secretory Rate | 1986 |
A pharmacological study of group I muscle afferent terminals and synaptic excitation in the intermediate nucleus and Clarke's column of the cat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Interneurons; Muscles; Neurons, Afferent; Piperidines; Spinal Cord; Synaptic Transmission | 1986 |
Neurobehavioral, neuroendocrine and neurochemical effects of zinc supplementation in rats.
Topics: Adrenocorticotropic Hormone; Animals; Baclofen; Behavior, Animal; beta-Endorphin; Brain; Diazepam; Endorphins; gamma-Aminobutyric Acid; In Vitro Techniques; Injections, Intraventricular; Naloxone; Pain; Pituitary Gland; Rats; Receptors, GABA-A; Receptors, Opioid; Seizures; Zinc | 1986 |
GABA-ergic control of alpha-melanocyte-stimulating hormone (alpha-MSH) release by frog neurointermediate lobe in vitro.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Immunoenzyme Techniques; Male; Melanocyte-Stimulating Hormones; Muscimol; Picrotoxin; Pituitary Gland, Anterior; Rana ridibunda; Synaptic Transmission | 1986 |
Characterization of gamma-aminobutyric acid receptors in the neurointermediate lobe of the amphibian Xenopus laevis.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Kinetics; Melanocyte-Stimulating Hormones; Picrotoxin; Pituitary Gland; Receptors, GABA-A; Taurine; Xenopus | 1987 |
Effect of chronic imipramine or baclofen on GABA-B binding and cyclic AMP production in cerebral cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Cyclic AMP; gamma-Aminobutyric Acid; Imipramine; Male; Mice; Norepinephrine; Receptors, GABA-A | 1986 |
GABAA receptors in the midbrain central grey mediate the antiaversive action of GABA.
Topics: Animals; Avoidance Learning; Baclofen; Electrodes, Implanted; gamma-Aminobutyric Acid; Isoxazoles; Male; Mesencephalon; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat.
Topics: Alkynes; Aminocaproates; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Isoxazoles; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Nigra | 1987 |
[Antiabstinent action of fenibut and baclofen on a model of abstinence induced by the benzodiazepine receptor antagonist CGS 8216 in rats receiving diazepam].
Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Drug Evaluation, Preclinical; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrazoles; Rats; Receptors, GABA-A; Substance Withdrawal Syndrome; Tranquilizing Agents | 1987 |
GABAB-receptor mediated inhibition of potassium-evoked release of endogenous 5-hydroxytryptamine from mouse frontal cortex.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Potassium; Receptors, GABA-A; Serotonin; Stereoisomerism | 1987 |
Axonal GABA receptors are selectively present on normal and regenerated sensory fibers in rat peripheral nerve.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Muscimol; Nerve Regeneration; Neurons, Afferent; Peripheral Nerves; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sciatic Nerve; Spinal Nerve Roots | 1987 |
Effects of GABA on gastric acid secretion and ulcer formation in rats.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Gastric Acid; Ligation; Male; Pylorus; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stomach Ulcer; Stress, Physiological | 1987 |
Diazepam potentiates GABA-contraction in guinea-pig ileum.
Topics: Animals; Baclofen; Benzodiazepinones; Carbolines; Diazepam; Drug Synergism; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth | 1986 |
Stereoselective analysis of racemic psychotropic compounds by HPLC on chiral stationary phase.
Topics: 5-Hydroxytryptophan; Baclofen; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; Oxazepam; Psychopharmacology; Psychotropic Drugs; Stereoisomerism; Tranylcypromine | 1986 |
GABA suppresses stimulation-induced release of [3H]-noradrenaline from sympathetic nerve fibres in bovine ovarian follicles.
Topics: Animals; Baclofen; Bicuculline; Cattle; Desipramine; Electric Stimulation; Female; gamma-Aminobutyric Acid; Hydroxydopamines; In Vitro Techniques; Muscimol; Norepinephrine; Normetanephrine; Ovarian Follicle; Oxidopamine; Potassium Chloride; Sympathectomy, Chemical; Sympathetic Nervous System | 1987 |
Evidence for G protein mediation of serotonin- and GABAB-induced hyperpolarization of rat dorsal raphe neurons.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Baclofen; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; In Vitro Techniques; Male; Membrane Potentials; Pertussis Toxin; Raphe Nuclei; Rats; Serotonin; Thionucleotides; Virulence Factors, Bordetella | 1988 |
Potential interactions between GABAb and cholinergic systems: baclofen augments scopolamine-induced performance deficits in the eight-arm radial maze.
Topics: Animals; Baclofen; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Male; Motor Activity; Parasympathetic Nervous System; Psychomotor Performance; Rats; Rats, Inbred F344; Scopolamine | 1988 |
Enhanced pressor response to GABA in the nucleus tractus solitarii of the spontaneously hypertensive rat.
Topics: Animals; Baclofen; Blood Pressure; Brain Stem; gamma-Aminobutyric Acid; Heart Rate; Hypertension; Male; Muscimol; Nipecotic Acids; Proline; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
Amygdaloid kindling with bicuculline methiodide in rats.
Topics: Amygdala; Animals; Baclofen; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains | 1988 |
Dopamine mediated behavior and GABA influence.
Topics: Animals; Apomorphine; Baclofen; Behavior, Animal; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains | 1988 |
Interaction between GABAergic neurotransmission and rat hypothalamic corticotropin-releasing hormone secretion in vitro.
Topics: Animals; Baclofen; Corticotropin-Releasing Hormone; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Male; Muscimol; Organ Culture Techniques; Rats; Rats, Inbred Strains; Serotonin | 1988 |
Inhibition of the voltage-dependent calcium currents in isolated frog sensory neurons by GABA-related agonistic compounds.
Topics: Animals; Baclofen; Barbiturates; Benzodiazepines; Calcium; Diazepam; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Muscimol; Neurons, Afferent; Rana catesbeiana; Taurine | 1988 |
Baclofen and gamma-aminobutyric acid differentially suppress the cutaneous responsiveness of primary somatosensory cortical neurones.
Topics: Animals; Baclofen; Cats; Evoked Potentials; gamma-Aminobutyric Acid; Neurons; Skin; Somatosensory Cortex | 1988 |
The role of GABA in morphine abstinence in rats.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; gamma-Aminobutyric Acid; Male; Morphine; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome | 1988 |
Delta-aminovaleric acid antagonizes the pharmacological actions of baclofen in the central nervous system.
Topics: Animals; Baclofen; Bicuculline; Drug Antagonism; Electric Stimulation; Female; gamma-Aminobutyric Acid; H-Reflex; Male; Muscimol; Muscle Contraction; Muscle Spasticity; Rabbits; Rats; Rats, Inbred Strains; Reflex, Monosynaptic; Spinal Cord; Valerates | 1988 |
Effects of GABA and baclofen on pyramidal cells in the developing rabbit hippocampus: an 'in vitro' study.
Topics: Animals; Baclofen; Cell Membrane; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Pyramidal Tracts; Rabbits; Reference Values | 1988 |
Cl- - and K+-dependent inhibitory postsynaptic potentials evoked by interneurones of the rat lateral geniculate nucleus.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Chlorides; gamma-Aminobutyric Acid; Geniculate Bodies; In Vitro Techniques; Interneurons; Male; Potassium; Rats; Rats, Inbred Strains; Synapses | 1988 |
The effects of GABA agonists and antagonists on rat gastric acid secretion.
Topics: Animals; Baclofen; Bicuculline; Deoxyglucose; GABA Antagonists; gamma-Aminobutyric Acid; Gastric Acid; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains | 1988 |
Effect of gamma-aminobutyric acid on human jejunum "in vitro".
Topics: Baclofen; gamma-Aminobutyric Acid; Gastrointestinal Motility; Humans; In Vitro Techniques; Jejunum; Muscle, Smooth; Picrotoxin | 1988 |
Intrathecal application of baclofen in the treatment of spasticity.
Topics: Adolescent; Adult; Baclofen; Female; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male; Middle Aged; Muscle Spasticity; Spinal Cord; Spinal Cord Diseases | 1987 |
Evidence for gamma-aminobutyric acid modulation of ovarian hormonal effects on luteinizing hormone secretion and hypothalamic catecholamine activity in the female rat.
Topics: alpha-Methyltyrosine; Animals; Baclofen; Bicuculline; Castration; Catecholamines; Epinephrine; Estradiol; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Hypothalamus, Middle; Luteinizing Hormone; Methyltyrosines; Muscimol; Norepinephrine; Preoptic Area; Progesterone; Rats | 1986 |
Spontaneous paroxysmal activity induced by zero magnesium and bicuculline: suppression by NMDA antagonists and GABA mimetics.
Topics: Animals; Aspartic Acid; Baclofen; Bicuculline; Corpus Callosum; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; N-Methylaspartate; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains | 1986 |
GABA and gonadotropin secretion: evidence from in vitro studies on regulation of LHRH secretion.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Arginine Vasopressin; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Male; Median Eminence; Muscimol; Orchiectomy; Oxytocin; Rats | 1986 |
An antinociceptive profile of kojic amine: an analogue of gamma-aminobutyric acid (GABA).
Topics: Animals; Atropine; Atropine Derivatives; Baclofen; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Morphine; Motor Activity; Pain; Pyrans; Pyrones | 1987 |
A case of glutaric aciduria type I with unique abnormalities in the cerebral CT findings.
Topics: Baclofen; Female; gamma-Aminobutyric Acid; Gas Chromatography-Mass Spectrometry; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Infant; Intellectual Disability; Metabolism, Inborn Errors; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Tomography, X-Ray Computed | 1987 |
Differing actions of beta-phenyl-GABA and baclofen in the guinea pig isolated ileum.
Topics: Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Muscle Contraction | 1987 |
Strychnine alters the fusiform cell output from the dorsal cochlear nucleus.
Topics: Acoustic Stimulation; Action Potentials; Animals; Auditory Pathways; Baclofen; Bicuculline; Chinchilla; gamma-Aminobutyric Acid; Glycine; Medulla Oblongata; Neurons; Strychnine | 1987 |
Injection of baclofen into the ventromedial hypothalamus stimulates gastric motility in the rat.
Topics: Animals; Atropine; Baclofen; gamma-Aminobutyric Acid; Gastrointestinal Motility; Hypothalamus, Middle; Male; Muscimol; Rats; Rats, Inbred Strains; Vagotomy | 1987 |
Effect of gamma-aminobutyric acid on neurally mediated contraction of guinea pig trachealis smooth muscle.
Topics: Acetylcholine; Animals; Baclofen; Furosemide; gamma-Aminobutyric Acid; Guinea Pigs; Hemicholinium 3; In Vitro Techniques; Muscimol; Muscle Contraction; Muscle, Smooth; Naloxone; Phentolamine; Propranolol; Trachea | 1987 |
[Effect of gamma-aminobutyric acid on cardiac inotropism in the anesthetized guinea pig].
Topics: Adrenalectomy; Anesthesia; Animals; Baclofen; Barbital; Blood Pressure; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Heart Rate; Male; Myocardial Contraction; Reserpine; Urethane | 1987 |
Effect of GABAergic drugs in the behavioral 'despair' test in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoxazoles; Male; Motor Activity; Muscimol; Oxazoles; Picrotoxin; Rats | 1986 |
Involvement of a GABAergic mechanism in the pharmacologic action of phenytoin.
Topics: Animals; Anticonvulsants; Baclofen; Electroshock; gamma-Aminobutyric Acid; Male; Mice; Phenytoin; Postural Balance; Seizures | 1986 |
Effects of baclofen and gamma-aminobutyric acid on different types of medullary respiratory neurons.
Topics: Animals; Baclofen; Cats; Female; gamma-Aminobutyric Acid; Iontophoresis; Male; Microinjections; Phrenic Nerve; Respiratory Center | 1986 |
Effects of GABA-mimetic drugs on turnover of histamine in the mouse brain.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Brain; Brain Chemistry; gamma-Aminobutyric Acid; Histamine; Isoxazoles; Male; Methylhistamines; Methylhistidines; Mice; Muscimol | 1986 |
Local and remote effects of intra-caudate administration of GABA-related drugs on Met-enkephalin release in the basal ganglia.
Topics: Animals; Baclofen; Basal Ganglia; Bicuculline; Calcium; Caudate Nucleus; Corpus Striatum; Egtazic Acid; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Potassium; Rats; Rats, Inbred Strains | 1985 |
Comparison of the action of baclofen with gamma-aminobutyric acid on rat hippocampal pyramidal cells in vitro.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Chlorides; Dendrites; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Potassium; Rats; Synapses | 1985 |
Subchronic administration of GABAergic agonists elevates [3H]GABA binding and produces tolerance in striatal dopamine catabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alkynes; Aminocaproates; Aminooxyacetic Acid; Animals; Baclofen; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Isoxazoles; Male; Pyrones; Rats; Rats, Inbred Strains; Vigabatrin | 1985 |
Adverse effects secondary to baclofen withdrawal.
Topics: Adult; Baclofen; Female; gamma-Aminobutyric Acid; Hallucinations; Humans; Intestinal Absorption; Muscle Spasticity; Substance Withdrawal Syndrome | 1985 |
Stability of the amino acid content of nerve endings after administration of gamma-aminobutyrate agonists and antagonists.
Topics: Amino Acids; Animals; Anticonvulsants; Aspartic Acid; Baclofen; Bicuculline; Brain Chemistry; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Mice; Muscimol; Nerve Endings; Picrotoxin; Synaptosomes | 1985 |
The role of the gamma-aminobutyrate system in the interactions of cortical evoked potentials.
Topics: Acoustic Stimulation; Animals; Baclofen; Bicuculline; Cats; Cerebral Cortex; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Picrotoxin | 1985 |
GABAergic mechanisms in antinociception.
Topics: Alkynes; Aminocaproates; Aminooxyacetic Acid; Analgesics; Animals; Baclofen; Bicuculline; Central Nervous System; gamma-Aminobutyric Acid; Isoxazoles; Mice; Muscimol; Pain; Rats; Stereoisomerism; Substance P; Synaptic Transmission; Vigabatrin | 1984 |
GABAB receptors and norepinephrine-stimulated cAMP production in rat brain cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Cyclic AMP; Drug Interactions; gamma-Aminobutyric Acid; Male; Norepinephrine; Pyrones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
3H-ACh release from guinea pig gallbladder evoked by GABA through the bicuculline-sensitive GABA receptor.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Choline; Female; Gallbladder; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Male; Muscimol; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1984 |
Functional and pharmacological differences between two types of GABA receptor on embryonic chick sensory neurons.
Topics: Animals; Baclofen; Bicuculline; Calcium; Chick Embryo; Chlorides; Culture Techniques; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channels; Membrane Potentials; Muscimol; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Sensory Receptor Cells; Synaptic Transmission | 1984 |
GABA and baclofen reduce changes in extracellular free calcium in area CA1 of rat hippocampal slices.
Topics: Animals; Baclofen; Culture Techniques; Dose-Response Relationship, Drug; Extracellular Space; gamma-Aminobutyric Acid; Hippocampus; Ion Channels; Membrane Potentials; Neurons; Rats; Synapses | 1984 |
Differences in baclofen-sensitivity between CA3 neurons and granule cells of the guinea pig hippocampus in vitro.
Topics: Animals; Baclofen; Bicuculline; Culture Techniques; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Membrane Potentials; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1984 |
GABAergic agents as anticonvulsants in baboons with photosensitive epilepsy.
Topics: Aminocaproates; Animals; Anticonvulsants; Baclofen; Carbolines; Cerebral Cortex; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Papio; Photic Stimulation; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Vigabatrin | 1984 |
Enhancement of high affinity gamma-aminobutyric acid receptor binding in cerebellum of pyridoxine-deficient rat.
Topics: Animals; Baclofen; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes; Vitamin B 6 Deficiency | 1984 |
Baclofen has a presynaptic action at the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; Baclofen; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Junction; Receptors, GABA-A; Synapses | 1984 |
Pretreatment with GABA and modulatory ligands enhances GABA receptor binding.
Topics: Animals; Baclofen; Binding Sites; Cerebral Cortex; Drug Interactions; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Membranes | 1984 |
gamma-Aminobutyric acid-ergic analgesia: implications for gamma-aminobutyric acid-ergic therapy for drug addictions.
Topics: Animals; Baclofen; Brain; Drug Tolerance; Endorphins; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Morphine; Morphine Dependence; Muscimol; Nociceptors; Rats; Receptors, GABA-A; Sensory Thresholds; Substance Withdrawal Syndrome; Substance-Related Disorders | 1984 |
Bicuculline-insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes.
Topics: Animals; Baclofen; Bicuculline; Cations, Divalent; Cerebellum; gamma-Aminobutyric Acid; Kinetics; Rats; Receptors, GABA-A; Synaptic Membranes | 1984 |
Baclofen: stereoselective inhibition of excitant amino acid release.
Topics: Amino Acids; Animals; Aspartic Acid; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Stereoisomerism | 1980 |
The effect of baclofen on the cardiovascular system of the rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arteries; Baclofen; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hexamethonium Compounds; Male; Rats; Reserpine; Vasodilation | 1980 |
GABAergic mechanisms in blood pressure control. A pharmacological analysis in the rat.
Topics: Animals; Baclofen; Blood Pressure; Brain; Cardiovascular System; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurotransmitter Agents; Norepinephrine; Rats | 1980 |
The effects of anaesthetics on the uptake and release of amino acid neurotransmitters in thalamic slices.
Topics: Anesthetics; Animals; Aspartic Acid; Baclofen; Bicuculline; Calcium; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Methohexital; Neurotransmitter Agents; Picrotoxin; Potassium; Rats; Rats, Inbred Strains; Thalamus | 1982 |
Baclofen: effects on evoked field potentials and amino acid neurotransmitter release in the rat olfactory cortex slice.
Topics: Animals; Aspartic Acid; Baclofen; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Neural Inhibition; Olfactory Bulb; Potassium; Rats; Synapses; Synaptic Transmission; Taurine | 1982 |
Effect of gamma-aminobutyric acid agonists, glycine, taurine and neuropeptides on acetylcholine release from the rabbit retina.
Topics: Acetylcholine; Animals; Baclofen; Electroretinography; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neurotransmitter Agents; Photic Stimulation; Rabbits; Retina; Strychnine; Taurine | 1983 |
GABAB receptor mediated inhibition of field stimulation-induced contractions of rabbit bladder muscle in-vitro.
Topics: Acetylcholine; Amino Acids; Amino Acids, Neutral; Animals; Atropine; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Hexamethonium; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Phentolamine; Picrotoxin; Rabbits; Receptors, Cell Surface; Receptors, GABA-A; Taurine; Tetrodotoxin; Urinary Bladder | 1984 |
Post-anoxic action myoclonus (Lance-Adams syndrome) treated with levodopa and GABAergic drugs.
Topics: Anticonvulsants; Baclofen; Drug Therapy, Combination; Female; gamma-Aminobutyric Acid; Humans; Hypoxia; Levodopa; Middle Aged; Myoclonus | 1980 |
Electrophysiological evidence for the existence of excitatory fibres in the caudato-nigral pathway in the cat.
Topics: Animals; Atropine; Baclofen; Cats; Caudate Nucleus; Electrophysiology; gamma-Aminobutyric Acid; Neural Pathways; Picrotoxin; Reaction Time; Substance P; Substantia Nigra | 1980 |
The effects of substance P and baclofen on motoneurones of isolated spinal cord of the newborn rat.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Calcium; gamma-Aminobutyric Acid; Glutamates; Glycine; In Vitro Techniques; Motor Neurons; Perfusion; Rats; Spinal Cord; Substance P | 1980 |
Further support for the postsynaptic action of substance P and its blockade with baclofen in neurons of the guinea-pig hypothalamus in vitro.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Neurons; Substance P; Synapses | 1981 |
Neuropharmacology in the brain slice: effects of substance P on neurons in the guinea-pig hypothalamus.
Topics: Animals; Baclofen; Electrophysiology; Female; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; In Vitro Techniques; Male; Neurons; Substance P | 1982 |
GABAB receptor-mediated inhibition of serotonin release in the rat brain.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; In Vitro Techniques; Male; Nipecotic Acids; Phentolamine; Picrotoxin; Proline; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Serotonin | 1984 |
Effect of neuroactive peptides on labeled 5-hydroxytryptamine release from rat spinal slices in vitro.
Topics: Animals; Baclofen; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nerve Tissue Proteins; Potassium; Rats; Rats, Inbred Strains; Serotonin; Somatostatin; Spinal Cord; Substance P; Trigeminal Nucleus, Spinal | 1984 |
(-)Baclofen decreases neurotransmitter release in the mammalian CNS by an action at a novel GABA receptor.
Topics: Animals; Baclofen; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Norepinephrine; Rats; Receptors, Neurotransmitter; Serotonin | 1980 |
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures | 1980 |
3H-baclofen and 3H-GABA bind to bicuculline-insensitive GABA B sites in rat brain.
Topics: Animals; Baclofen; Bicuculline; Binding, Competitive; Brain; Calcium; GABA Antagonists; gamma-Aminobutyric Acid; Magnesium; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1981 |
Bicuculline-insensitive GABA receptors on peripheral autonomic nerve terminals.
Topics: Animals; Autonomic Nervous System; Baclofen; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; Heart Atria; Male; Norepinephrine; Rats; Receptors, Cell Surface; Receptors, GABA-A; Vas Deferens | 1981 |
The depressant action of baclofen on the isolated spinal cord of the neonatal rat.
Topics: Amino Acids; Animals; Animals, Newborn; Baclofen; Depression, Chemical; gamma-Aminobutyric Acid; In Vitro Techniques; Rats; Spinal Cord; Structure-Activity Relationship; Synaptic Transmission | 1981 |
GABA and baclofen potentiate the K+-evoked release of methionine-enkephalin from rat striatal slices.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Corpus Striatum; Drug Synergism; Endorphins; Enkephalin, Methionine; Enkephalins; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Picrotoxin; Potassium; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Two types of gamma-aminobutyric acid receptor on embryonic sensory neurones.
Topics: Action Potentials; Animals; Baclofen; Chick Embryo; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Neurons, Afferent; Receptors, Cell Surface; Receptors, GABA-A | 1981 |
Baclofen selectively inhibits excitatory synaptic transmission in the hippocampus.
Topics: Animals; Baclofen; Culture Techniques; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Nerve Fibers; Neural Inhibition; Rats; Synapses; Synaptic Transmission | 1981 |
Autoradiographic localization of GABAB receptors in rat cerebellum.
Topics: Animals; Autoradiography; Baclofen; Brain Mapping; Cerebellum; gamma-Aminobutyric Acid; Rats; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Structure-Activity Relationship | 1981 |
[GH after baclofen and diazepam].
Topics: Baclofen; Diazepam; Drug Interactions; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Receptors, Cell Surface; Receptors, GABA-A; Time Factors | 1981 |
Evidence for a neuromodulatory role of GABA at the first synapse of the baroreceptor reflex pathway. Effects of GABA derivatives injected into the NTS.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Female; gamma-Aminobutyric Acid; Heart Rate; Male; Medulla Oblongata; Muscimol; Pressoreceptors; Receptors, Cell Surface; Receptors, GABA-A; Reflex | 1982 |
[GABA and drug effects on the central nervous system].
Topics: Anticonvulsants; Baclofen; Benzodiazepines; Central Nervous System; gamma-Aminobutyric Acid; Humans; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
GABAA- and GABAB-receptor-mediated modification of intestinal motility.
Topics: Animals; Baclofen; Colon; Female; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, GABA-A | 1982 |
GABAA and GABAB receptor-mediated effects in guinea-pig ileum.
Topics: Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Receptors, Cell Surface; Receptors, GABA-A; Taurine | 1983 |
Modulation of GABA receptor binding by Ca2+.
Topics: Animals; Baclofen; Calcium; Cerebral Cortex; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1983 |
Bicuculline insensitive effects of baclofen.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Male; Motor Activity; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter | 1983 |
Presynaptic GABAB receptors and the regulation of [3H]noradrenaline release from rat anococcygeus muscle.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscles; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
GABA and lioresal actions on the identified Onchidium neuron.
Topics: Animals; Baclofen; Biomechanical Phenomena; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Ganglia; Ion Channels; Ions; Magnesium; Neurons; Snails | 1983 |
The action of benzodiazepine antagonist Ro 15-1788 on the effects of GABA-ergic drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Baclofen; Benzodiazepines; Benzodiazepinones; Brain Chemistry; Flumazenil; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Inhibition of GABAB receptor binding by guanyl nucleotides.
Topics: Animals; Baclofen; Brain; Calcium Chloride; gamma-Aminobutyric Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; Kinetics; Rats; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Membranes | 1984 |
gamma-aminobutyric acid B receptors are negatively coupled to adenylate cyclase in brain, and in the cerebellum these receptors may be associated with granule cells.
Topics: Adenylyl Cyclases; Animals; Baclofen; Brain; Cerebellum; Cytoplasmic Granules; gamma-Aminobutyric Acid; Kinetics; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Baclofen reduces tone-evoked activity of cochlear nucleus neurons.
Topics: 2-Aminoadipic Acid; Acoustic Stimulation; Animals; Aspartic Acid; Baclofen; Bicuculline; Chinchilla; Cochlear Nerve; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Loudness Perception; Neural Inhibition; Neurons; Pitch Perception; Receptors, Amino Acid; Receptors, Cell Surface; Synaptic Transmission | 1984 |
GABAB receptor-mediated stimulation of the contractility of isolated rabbit oviduct.
Topics: Animals; Baclofen; Fallopian Tubes; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Muscle Contraction; Rabbits; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Gaba-ergic and dopaminergic regulation of thyroid stimulating hormone. Effects of baclofen and metoclopramide.
Topics: Adult; Baclofen; Dopamine; Dopamine Antagonists; gamma-Aminobutyric Acid; Humans; Male; Metoclopramide; Thyroid Hormones; Thyrotropin; Thyrotropin-Releasing Hormone | 1984 |
Enhancement of spike and wave discharges by GABAmimetic drugs in rats with spontaneous petit-mal-like epilepsy.
Topics: Action Potentials; Aminocaproates; Animals; Baclofen; Epilepsy, Absence; gamma-Aminobutyric Acid; Isoxazoles; Muscimol; Rats; Vigabatrin | 1984 |
Huntington's chorea.
Topics: Baclofen; Canada; gamma-Aminobutyric Acid; Health Facilities; Humans; Huntington Disease; Hydroxybutyrates; Sodium Oxybate | 1982 |
Hyperpolarizing action of baclofen on neurons in the rat substantia nigra slice.
Topics: Animals; Baclofen; Bicuculline; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Rats; Substantia Nigra | 1984 |
[Nootropic properties of gamma-aminobutyric acid derivatives].
Topics: Amnesia; Amnesia, Retrograde; Animals; Avoidance Learning; Baclofen; Butyrates; Conditioning, Classical; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Hypoxia; Lithium; Mice; Organometallic Compounds; Piracetam; Sodium Oxybate | 1984 |
Self-injurious behavior in rats produced by intranigral microinjection of GABA agonists.
Topics: Animals; Baclofen; Bicuculline; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Male; Microinjections; Muscimol; Rats; Rats, Inbred Strains; Self Mutilation; Stress, Physiological; Substantia Nigra | 1984 |
Unilateral injection of GABA agonists in the superior colliculus: asymmetry to tactile stimulation.
Topics: Analgesics; Animals; Baclofen; Functional Laterality; gamma-Aminobutyric Acid; Isoxazoles; Motor Activity; Muscimol; Oxazoles; Physical Stimulation; Rats; Rats, Inbred Strains; Superior Colliculi; Touch | 1983 |
Effects of baclofen on synaptically-induced cell firing in the rat hippocampal slice.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Pyramidal Tracts; Rats; Rats, Inbred Strains; Stereoisomerism; Taurine | 1983 |
Inhibition by GABA, baclofen and gabapentin of dopamine release from rabbit caudate nucleus: are there common or different sites of action?
Topics: Acetates; Amines; Animals; Baclofen; Bicuculline; Binding Sites; Caudate Nucleus; Cyclohexanecarboxylic Acids; Dopamine; Female; Gabapentin; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Rabbits | 1983 |
Involvement of GABA in the antinociceptive effect of gamma-acetylenic GABA (GAG), an inhibitor of GABA-transaminase.
Topics: 4-Aminobutyrate Transaminase; Alkynes; Aminocaproates; Analgesics; Animals; Baclofen; Bicuculline; Drug Interactions; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Theophylline; Time Factors | 1983 |
Growth hormone secretion of the neonatal rat pituitaries is stimulated by gamma-aminobutyric acid in vitro.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Growth Hormone; In Vitro Techniques; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Strychnine | 1984 |
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate | 1984 |
Actions of gamma-aminobutyric acid on neurones of guinea-pig myenteric plexus.
Topics: Acetylcholine; Alanine; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Glycine; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Myenteric Plexus; Neural Conduction; Neuromuscular Depolarizing Agents; Neurons; Nipecotic Acids; Picrotoxin; Proline; Tetrodotoxin | 1984 |
Basic and regulatory mechanisms of in vitro release of Met-enkephalin from the dorsal zone of the rat spinal cord.
Topics: Animals; Baclofen; Bicuculline; Enkephalin, Methionine; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Nerve Tissue Proteins; Perfusion; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Tritium | 1984 |
Effects of some gamma-aminobutyric acid (GABA)-ergic drugs on the dopaminergic control of human growth hormone secretion.
Topics: Adult; Apomorphine; Baclofen; Diazepam; Dopamine; gamma-Aminobutyric Acid; Growth Hormone; Humans; Levodopa; Male; Valproic Acid | 1980 |
Discriminative stimulus effects of pentobarbital in pigeons.
Topics: Animals; Baclofen; Bemegride; Columbidae; Ethanol; gamma-Aminobutyric Acid; Muscimol; Pentobarbital; Prejudice | 1980 |
[Protective effects of muscimol on acute brain ischemia in the rat (author's transl)].
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Kinetics; Male; Muscimol; Oxazoles; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Nigral actions of GABA agonists are enhanced by chronic fluphenazine and differentiated by concomitant flurazepam.
Topics: Animals; Baclofen; Bicuculline; Female; Fluphenazine; Flurazepam; gamma-Aminobutyric Acid; Humans; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra | 1982 |
GABAergic influences on defensive fighting in rats.
Topics: Aggression; Aminocaproates; Animals; Baclofen; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Humans; Male; Motor Activity; Muscimol; Picrotoxin; Rats; Rats, Inbred Strains; Valproic Acid; Vigabatrin | 1982 |
Baclofen blocks postsynaptic inhibition but not the effect of muscimol in the olfactory cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Neural Conduction; Neural Inhibition; Olfactory Pathways; Oxazoles; Synapses | 1983 |
Regulation by divalent cations of 3H-baclofen binding to GABAB sites in rat cerebellar membranes.
Topics: Animals; Baclofen; Binding Sites; Calcium; Cations, Divalent; Cell Fractionation; Cerebellum; gamma-Aminobutyric Acid; Ligands; Rats; Synaptic Membranes; Tritium | 1983 |
Kainate-enhanced release of D-[3H]aspartate from cerebral cortex and striatum: reversal by baclofen and pentobarbital.
Topics: Animals; Aspartic Acid; Baclofen; Biological Transport; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glucose; Guinea Pigs; Kainic Acid; Kinetics; Phenobarbital; Pyrrolidines; Sodium; Tritium | 1983 |
GABAergic drugs, morphine and morphine tolerance: a study in relation to nociception and gastrointestinal transit in mice.
Topics: Aminooxyacetic Acid; Analgesia; Animals; Baclofen; Bicuculline; Cyclohexanecarboxylic Acids; Digestion; Digestive System; Digestive System Physiological Phenomena; Drug Tolerance; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Morphine; Muscimol; Naloxone; Nociceptors; Oxazoles; Picrotoxin | 1983 |
Two actions of gamma-aminobutyric acid on the responses of the isolated basilar artery from the rabbit.
Topics: Animals; Baclofen; Basilar Artery; Drug Interactions; Electric Stimulation; Female; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits; Serotonin; Taurine | 1982 |
On the involvement of GABA in the analgesia produced by baclofen, muscimol and morphine.
Topics: 4-Aminobutyrate Transaminase; Analgesia; Analgesics; Animals; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Naloxone; Picrotoxin; Transaminases | 1982 |
[Presynaptic component in the mechanism of fenibut action].
Topics: Animals; Baclofen; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin; Rats; Rats, Inbred Strains; Synaptosomes | 1982 |
Effect of baclofen and haloperidol on gamma-aminobutyric acid and dopamine systems in an animal model of tardive dyskinesia.
Topics: Animals; Baclofen; Brain Chemistry; Disease Models, Animal; Dopamine; Drug Interactions; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Haloperidol; Male; Rats; Rats, Inbred Strains | 1982 |
Removal of the telencephalon spares turning induced by injection of GABA agonists and antagonists into the substantia nigra.
Topics: Aminobutyrates; Animals; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Neural Pathways; Picrotoxin; Rats; Rats, Inbred Strains; Stereotyped Behavior; Substantia Nigra; Telencephalon; Thalamus | 1980 |
Selective depression of synaptic excitation in cat spinal neurones by baclofen: an iontophoretic study.
Topics: 2-Aminoadipic Acid; Animals; Baclofen; Cats; Female; gamma-Aminobutyric Acid; Iontophoresis; Male; Neurons; Norepinephrine; Serotonin; Spinal Cord; Synapses | 1981 |
GABA enhancement of [3H]dopamine release from slices of rat striatum: dependence on slice size.
Topics: Animals; Baclofen; Corpus Striatum; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Male; Potassium; Rats | 1981 |
Baclofen as an anticonvulsant in experimental models of convulsions.
Topics: 3-Mercaptopropionic Acid; Acoustic Stimulation; Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Pentylenetetrazole; Rats; Seizures | 1981 |
GABA-ergic mechanisms in central respiratory control in the anesthetized rat.
Topics: Animals; Baclofen; Blood Gas Analysis; Blood Pressure; gamma-Aminobutyric Acid; Halothane; Heart Rate; Hydroxybutyrates; Injections, Intraventricular; Male; Muscimol; Rats; Rats, Inbred Strains; Respiration; Sodium Oxybate | 1981 |
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Motor Activity; Muscimol; Pain; Phencyclidine; Reflex | 1980 |
Effect of GABA analogues on blood pressure and central GABA metabolism in the rat.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Blood Pressure; Brain; Dopamine; gamma-Aminobutyric Acid; Heart Rate; Hydroxybutyrates; Male; Muscimol; Picrotoxin; Rats; Sodium Oxybate | 1980 |
Inhibition of depressor cardiovascular reflexes by a derivative of gamma-aminobutyric acid (GABA) and by general anesthetics with suspected GABA-mimetic effects.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Blood Pressure; Cats; Chloralose; Female; gamma-Aminobutyric Acid; Male; Methohexital; Picrotoxin; Reflex; Sympathetic Nervous System; Urethane | 1980 |
Calcium channel involvement in GABAB receptor-mediated inhibition of GABA release in area CA1 of the rat hippocampus.
Topics: Action Potentials; Animals; Baclofen; Calcium Channel Blockers; Calcium Channels; Electrophysiology; GABA Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Interneurons; Male; Nerve Endings; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synapses | 1995 |
Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide.
Topics: Animals; Arachidonic Acids; Baclofen; Calcium Channel Blockers; Chloride Channels; Endocannabinoids; Furosemide; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Models, Neurological; Polyunsaturated Alkamides; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Snails; Synapses; Synaptic Transmission | 1995 |
[Co-involvement of catecholaminergic and gabaergic transmission in the electro-cortical response to central galanin administration in the rabbit].
Topics: alpha-Methyltyrosine; Animals; Baclofen; Catecholamines; Ditiocarb; Drug Interactions; Electroencephalography; GABA Antagonists; Galanin; gamma-Aminobutyric Acid; Injections, Intraventricular; Methyltyrosines; Muscimol; Peptides; Rabbits; Synaptic Transmission | 1993 |
GABAergic modulation of striatal peptide expression in rats and the alterations induced by dopamine antagonist treatment.
Topics: Animals; Baclofen; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Enkephalins; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutamate Decarboxylase; Haloperidol; In Situ Hybridization; Male; Muscimol; Protein Precursors; Rats; Rats, Wistar; Receptors, GABA; RNA, Messenger; Salicylamides; Substance P; Tachykinins; Vigabatrin | 1994 |
Age-dependent effects of gamma-aminobutyric acid agents on flurothyl seizures.
Topics: Age Factors; Animals; Anticonvulsants; Baclofen; Convulsants; Flurothyl; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Seizures; Vigabatrin | 1995 |
Extracellular GABA in the ventrolateral thalamus of rats exhibiting spontaneous absence epilepsy: a microdialysis study.
Topics: Animals; Baclofen; Electroencephalography; Epilepsy, Absence; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Microdialysis; Nipecotic Acids; Organophosphorus Compounds; Potassium; Rats; Rats, Wistar; Stereoisomerism; Thalamus; Tiagabine | 1995 |
A depolarizing inhibitory response to GABA in brainstem auditory neurons of the chick.
Topics: Animals; Baclofen; Basal Ganglia; Bicuculline; Brain Stem; Chickens; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Neuromuscular Depolarizing Agents; Neurons, Afferent; Patch-Clamp Techniques | 1995 |
Interaction between glutamate and GABA on 3H-noradrenaline release from rat hypothalamus.
Topics: Animals; Baclofen; Drug Interactions; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamus; Kainic Acid; Male; N-Methylaspartate; Norepinephrine; Potassium; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
Sympatholytic effect of tricyclic antidepressants: site and mechanism of action in anesthetized rats.
Topics: Adrenergic alpha-Antagonists; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Baclofen; Blood Pressure; Brain Mapping; Desipramine; Dioxanes; Fluoxetine; gamma-Aminobutyric Acid; Idazoxan; Imidazoles; Male; Medulla Oblongata; Microinjections; Nordefrin; Oxidopamine; Rats; Rats, Sprague-Dawley; Splanchnic Nerves; Sympatholytics; Time Factors | 1995 |
Acute increase of GABAergic neurotransmission exerts a stimulatory effect on GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized, estrogen- and progesterone-treated adult female rats.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Estradiol; Female; gamma-Aminobutyric Acid; Gene Expression; Gonadotropin-Releasing Hormone; Hypothalamus; Hypothalamus, Anterior; Muscimol; Ovariectomy; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Synaptic Transmission | 1995 |
A novel gamma-aminobutyric acid response in the embryonic brainstem as revealed by voltage-sensitive dye recording.
Topics: Animals; Baclofen; Brain Stem; Chick Embryo; Coloring Agents; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Picrotoxin | 1995 |
Inhibitory actions of GABA on rabbit urinary bladder muscle strips: mediation by potassium channels.
Topics: Animals; Baclofen; Carbachol; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Potassium Channels; Rabbits; Urinary Bladder | 1995 |
GABAB-mediated modulation of ionic conductances in type I hair cells isolated from guinea-pig semicircular canals.
Topics: Animals; Baclofen; Calcium; Cytosol; Electrophysiology; gamma-Aminobutyric Acid; Guinea Pigs; Hair Cells, Auditory; In Vitro Techniques; Ion Channels; Membrane Potentials; Picrotoxin; Semicircular Canals | 1993 |
Gamma-aminobutyric acidB, but not gamma-aminobutyric acidA receptor activation, inhibits electrically evoked substance P-like immunoreactivity release from the rat spinal cord in vitro.
Topics: Animals; Baclofen; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Substance P | 1993 |
GABAA receptor-mediated inhibition of N-methyl-D-aspartate-evoked [3H]dopamine release from mesencephalic cell cultures.
Topics: Animals; Baclofen; Cells, Cultured; Dopamine; Flunitrazepam; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kainic Acid; Mesencephalon; Muscimol; N-Methylaspartate; Picrotoxin; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA; Ventral Tegmental Area | 1994 |
Postnatal development of pre- and postsynaptic GABAB-mediated inhibitions in the CA3 hippocampal region of the rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Developmental Biology; Electric Stimulation; gamma-Aminobutyric Acid; Hippocampus; Male; Presynaptic Terminals; Rats; Rats, Wistar; Synapses | 1995 |
Baclofen enhancement of acetylcholine release from amacrine cells in the rabbit retina by reduction of glycinergic inhibition.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Muscarine; Organophosphorus Compounds; Rabbits; Retina; Strychnine | 1995 |
The role of mesoaccumbens--pallidal circuitry in novelty-induced behavioral activation.
Topics: Animals; Baclofen; Behavior, Animal; Dopamine; Dopamine Agonists; Exploratory Behavior; Fluphenazine; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Limbic System; Locomotion; Male; Microinjections; Muscimol; Neostriatum; Neural Pathways; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra; Ventral Tegmental Area | 1995 |
Characterization of synaptic connections between cortex and deep nuclei of the rat cerebellum in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cerebellar Nuclei; Cerebral Cortex; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lysine; Muscimol; Neural Pathways; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Tetrodotoxin; Vestibular Nucleus, Lateral | 1995 |
Presynaptic inhibition by baclofen of retinohypothalamic excitatory synaptic transmission in rat suprachiasmatic nucleus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Male; Optic Chiasm; Optic Nerve; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Suprachiasmatic Nucleus; Synaptic Transmission | 1995 |
Multiple GABA receptor subtypes mediate inhibition of calcium influx at rat retinal bipolar cell terminals.
Topics: Animals; Axons; Baclofen; Bicuculline; Calcium; Cells, Cultured; gamma-Aminobutyric Acid; Nerve Endings; Organophosphorus Compounds; Picrotoxin; Potassium; Propylamines; Rats; Receptors, GABA; Receptors, GABA-A; Retina | 1995 |
Modulation of GABAC receptors in rat retinal bipolar cells by protein kinase C.
Topics: Animals; Baclofen; Bicuculline; Cell Polarity; Cycloleucine; Down-Regulation; Electrophysiology; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, GABA; Receptors, Serotonin; Retina | 1994 |
Facilitation of an NMDA receptor-mediated EPSP by paired-pulse stimulation in rat neocortex via depression of GABAergic IPSPs.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Auditory Cortex; Baclofen; Cerebral Cortex; Cesium; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus | 1994 |
Further evidence for the interactions between angiotensin II and GABAergic transmission in pentylenetetrazol kindling seizures in mice.
Topics: Angiotensin II; Animals; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Phenylurea Compounds; Receptors, GABA; Seizures | 1995 |
Effect of GABAergic compounds on gonadotropin-releasing hormone receptor gene expression in the rat.
Topics: Animals; Baclofen; Base Sequence; Brain; Cloning, Molecular; DNA Primers; DNA, Complementary; Female; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression; Molecular Sequence Data; Muscimol; Mutation; Polymerase Chain Reaction; Rats; Receptors, LHRH; RNA, Messenger; Tissue Distribution | 1995 |
Biochemical and functional identification of GABA receptors in Hydra vulgaris.
Topics: Animals; Baclofen; Bicuculline; Binding, Competitive; Diazepam; Feeding Behavior; gamma-Aminobutyric Acid; Glutathione; Hydra; Kinetics; Membranes; Receptors, GABA; Sensitivity and Specificity; Stimulation, Chemical; Tritium | 1995 |
Mechanism of action of gamma-aminobutyric acid on frog melanotrophs.
Topics: Adenylyl Cyclases; Animals; Baclofen; Calcium; Calcium Channels; Colforsin; Cyclic AMP; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inositol Phosphates; Male; Melanocyte-Stimulating Hormones; Models, Biological; Pituitary Gland, Posterior; Rana ridibunda; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; Taurine | 1995 |
Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): a possible mechanism for the generation of absence-like seizures induced by GH
Topics: Action Potentials; Animals; Baclofen; Epilepsy, Absence; Extracellular Space; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Organophosphorus Compounds; Potassium; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, GABA-B; Sodium Oxybate; Thalamic Nuclei | 1995 |
GABAergic regulation of tuberoinfundibular dopaminergic neurons in the male rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Baclofen; Dopamine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Isonicotinic Acids; Male; Neurons; Osmolar Concentration; Prolactin; Pyridazines; Rats; Rats, Inbred Strains; Seizures | 1994 |
Endogenous GABA attenuates CNS white matter dysfunction following anoxia.
Topics: Animals; Axons; Baclofen; Central Nervous System Diseases; Enzyme Activation; Female; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hypoxia; Neural Conduction; Neuroprotective Agents; Optic Nerve; Osmolar Concentration; Protein Kinase C; Rats; Receptors, GABA; Time Factors | 1995 |
Differing actions of nitropropane analogs of GABA and baclofen in central and peripheral preparations.
Topics: Animals; Baclofen; Cats; Cerebral Cortex; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Membrane Potentials; Nitroparaffins; Propane; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 1994 |
Effect of gamma-aminobutyric acid on synaptic transmission and long-term potentiation in rat superior cervical ganglion.
Topics: Action Potentials; Animals; Baclofen; Electric Stimulation; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Long-Term Potentiation; Male; Muscimol; Rats; Rats, Wistar; Receptors, Nicotinic; Synaptic Transmission | 1994 |
Attenuation of a voltage-dependent sodium current by GABA (identified neurons, buccal ganglia, Helix pomatia).
Topics: Animals; Baclofen; Cobalt; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Helix, Snails; In Vitro Techniques; Membrane Potentials; Muscimol; Neurons; Patch-Clamp Techniques; Sodium Channels | 1994 |
Transient expression of a novel type of GABA response in rat CA3 hippocampal neurones during development.
Topics: Aging; Animals; Animals, Newborn; Baclofen; Bicuculline; gamma-Aminobutyric Acid; Hippocampus; Neurons; Rats; Rats, Wistar; Receptors, GABA; Time Factors | 1994 |
Dorsal column inhibition of nociceptive thalamic cells mediated by gamma-aminobutyric acid mechanisms in the cat.
Topics: Afferent Pathways; Animals; Baclofen; Cats; Dental Pulp; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Homocysteine; Pain; Picrotoxin; Spinal Cord; Thalamus | 1994 |
GABA and glutamate release affected by GABAB receptor antagonists with similar potency: no evidence for pharmacologically different presynaptic receptors.
Topics: Animals; Baclofen; Benzylamines; Cerebral Cortex; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Inbred Strains; Receptors, GABA-B; Receptors, Presynaptic | 1994 |
GABAA- and GABAB-mediated inhibition in the rat dentate gyrus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electric Stimulation; Epilepsy; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synapses | 1993 |
Role of glutamatergic synaptic transmission in synchronized discharges of hilar neurons in guinea pig hippocampal slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Picrotoxin; Quinoxalines; Receptors, GABA-B; Receptors, Glutamate; Synaptic Transmission; Time Factors | 1993 |
Chemical modulation of synaptic transmission in the striatum.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Kynurenic Acid; Muscarine; Quinoxalines; Rats; Receptors, Dopamine D2; Receptors, GABA-B; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1993 |
Extrasynaptic effects of GABA (gamma-aminobutyric acid) agonists on myelinated axons of peripheral nerve.
Topics: Action Potentials; Animals; Axons; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Isoxazoles; Motor Neurons; Nerve Fibers, Myelinated; Peripheral Nerves; Rana catesbeiana; Ranidae; Sciatic Nerve; Spinal Nerve Roots; Synapses | 1994 |
Phosphorylation of DARPP-32 is regulated by GABA in rat striatum and substantia nigra.
Topics: Animals; Baclofen; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine and cAMP-Regulated Phosphoprotein 32; GABA Antagonists; gamma-Aminobutyric Acid; Male; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Nigra | 1994 |
Pharmacological discrimination between gamma-aminobutyric acid type B receptors regulating cholecystokinin and somatostatin release from rat neocortex synaptosomes.
Topics: Animals; Baclofen; Benzylamines; Cerebral Cortex; Cholecystokinin; GABA Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ligands; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Somatostatin; Synaptosomes | 1994 |
Glutamatergic hippocampal formation projections to prefrontal cortex in the rat are regulated by GABAergic inhibition and show convergence with glutamatergic projections from the limbic thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Brain Mapping; Electric Stimulation; Electrophysiology; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Neurons; Organophosphorus Compounds; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thalamus | 1994 |
Presynaptic actions of GABA and baclofen in CA1 region of the guinea-pig hippocampus in vitro.
Topics: Animals; Baclofen; Bicuculline; Calcium; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Organophosphorus Compounds; Picrotoxin; Receptors, Presynaptic; Sesterterpenes; Tetrodotoxin | 1994 |
Influence of gamma-aminobutyric acid on baclofen intestinal absorption.
Topics: Animals; Baclofen; Chromatography, High Pressure Liquid; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Absorption; Male; Models, Biological; Perfusion; Rats; Rats, Wistar | 1994 |
GABA uptake into isolated retinal Müller glial cells of the guinea-pig detected electrophysiologically.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Membrane Potentials; Muscimol; Neuroglia; Retina | 1994 |
GABA in the inferior colliculus plays a critical role in control of audiogenic seizures.
Topics: Acoustic Stimulation; Amino Acids; Animals; Baclofen; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Inferior Colliculi; Microinjections; Pons; Rats; Rats, Inbred Strains; Receptors, GABA-B; Reticular Formation; Seizures; Synaptosomes | 1994 |
GABAergic inactivation of the central pattern generators for locomotion in isolated neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Baclofen; gamma-Aminobutyric Acid; In Vitro Techniques; Locomotion; N-Methylaspartate; Rats; Spinal Cord | 1994 |
Biphasic gabaergic regulation of GnRH secretion in GT1 cell lines.
Topics: Animals; Baclofen; Cell Line; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Mice, Transgenic; Muscimol; Neurons; Receptors, GABA | 1994 |
GABA-B receptor-mediated spinal inhibition.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Cats; Decerebrate State; Depression, Chemical; GABA Antagonists; gamma-Aminobutyric Acid; Organophosphorus Compounds; Phosphinic Acids; Receptors, GABA; Reflex, Monosynaptic; Spinal Cord; Tetany | 1994 |
A possible inhibitory action of baclofen on hippocampus GABAergic neurones.
Topics: Animals; Baclofen; Biomarkers; Brain; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; In Vitro Techniques; Male; Neurons; Rats; Rats, Wistar; Spectrometry, Fluorescence | 1994 |
GABA synapses formed in vitro by local axon collaterals of nucleus accumbens neurons.
Topics: Animals; Animals, Newborn; Axons; Baclofen; Bicuculline; Cells, Cultured; Electrophysiology; gamma-Aminobutyric Acid; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reaction Time; Synapses | 1994 |
GABAB-receptor-mediated inhibition of calcium signals in isolated nerve terminals.
Topics: Animals; Baclofen; Calcium; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Signal Transduction; Synaptosomes | 1994 |
The role of GABA-mediated inhibition in the rat ventral posterior medial thalamus. II. Differential effects of GABAA and GABAB receptor antagonists on responses of VPM neurons.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Brain Mapping; Evoked Potentials, Somatosensory; Female; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Rats; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Thalamic Nuclei; Vibrissae | 1994 |
Synchronization of inhibitory neurones in the guinea-pig hippocampus in vitro.
Topics: 4-Aminopyridine; Animals; Baclofen; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Interneurons; Membrane Potentials; Microelectrodes; Neurons; Picrotoxin; Pyramidal Cells; Synaptic Transmission | 1994 |
Monosynaptic GABA-mediated inhibitory postsynaptic potentials in CA1 pyramidal cells of hyperexcitable hippocampal slices from kainic acid-treated rats.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Neurons; Pyramidal Tracts; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1993 |
Release of endogenous glutamic and aspartic acids from cerebrocortex synaptosomes and its modulation through activation of a gamma-aminobutyric acidB (GABAB) receptor subtype.
Topics: Animals; Aspartic Acid; Baclofen; Bicuculline; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Male; Organophosphorus Compounds; Picrotoxin; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
GABA mediation of the dual effects of somatostatin on guinea pig ileal myenteric cholinergic transmission.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Animals; Baclofen; Bicuculline; Cholecystokinin; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Pertussis Toxin; Receptors, GABA-A; Somatostatin; Virulence Factors, Bordetella | 1993 |
Long-term GABA treatment elicits supersensitivity of quisqualate-preferring metabotropic glutamate receptor in cultured rat cerebellar neurons.
Topics: Animals; Baclofen; Carbachol; Cells, Cultured; Cerebellum; Drug Tolerance; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kainic Acid; N-Methylaspartate; Neurons; Potassium Chloride; Pyridazines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glutamate | 1993 |
CGP 55845A blocks baclofen, gamma-aminobutyric acid and inhibitory postsynaptic potassium currents in guinea pig CA3 neurons.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Electrophysiology; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Picrotoxin; Potassium Channels; Quinoxalines; Synapses | 1993 |
CGP 52432: a novel potent and selective GABAB autoreceptor antagonist in rat cerebral cortex.
Topics: Animals; Baclofen; Benzylamines; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Wistar; Somatostatin | 1993 |
Effects of the nerve agents soman and tabun on the uptake and release of GABA and glutamate in synaptosomes of guinea pig cerebral cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Cholinesterase Inhibitors; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Guinea Pigs; In Vitro Techniques; Neurotransmitter Agents; Organophosphates; Rats; Soman; Synaptosomes | 1993 |
Depression of glutamatergic and GABAergic synaptic responses in striatal spiny neurons by stimulation of presynaptic GABAB receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Corpus Striatum; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; In Vitro Techniques; Lidocaine; Male; Neurons; Pregnanolone; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sodium Channel Blockers; Synapses | 1993 |
Plasticity of GABAB receptor in rat spinal cord detected by autoradiography.
Topics: Animals; Autoradiography; Baclofen; Binding Sites; gamma-Aminobutyric Acid; Organophosphorus Compounds; Phosphinic Acids; Rats; Receptors, GABA-B; Spinal Cord; Up-Regulation | 1993 |
Enteric GABA-containing nerves projecting to the guinea-pig inferior mesenteric ganglion modulate acetylcholine release.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Colon; Diazepam; Electric Stimulation; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Guinea Pigs; In Vitro Techniques; Male; Mesentery; Muscimol; Neural Pathways; Receptors, GABA-A; Receptors, GABA-B; Splanchnic Nerves; Synaptic Transmission | 1993 |
A role for computer simulation in solving the riddles of autoreceptor-mediated regulation of GABA release.
Topics: Animals; Baclofen; Computer Simulation; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurotransmitter Uptake Inhibitors; Organophosphorus Compounds; Rats; Receptors, GABA; Receptors, GABA-B; Software | 1993 |
GABA has excitatory actions on GnRH-secreting immortalized hypothalamic (GT1-7) neurons.
Topics: Animals; Baclofen; Bicuculline; Calcium; Cells, Cultured; Chloride Channels; Electric Stimulation; Electrophysiology; Fura-2; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Membrane Potentials; Mice; Neurons; Receptors, GABA-A; Sodium Channels; Spectrometry, Fluorescence; Stimulation, Chemical; Tetrodotoxin | 1994 |
[The participation of the GABAergic system of the brain in shaping the breathing rhythm].
Topics: Animals; Apnea; Baclofen; Cats; Electromyography; Female; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Periodicity; Receptors, GABA; Respiration; Respiratory Muscles; Sodium Oxybate | 1993 |
Stiff man syndrome: clinical and laboratory findings in eight patients.
Topics: Adult; Aged; Autoantibodies; Autoimmune Diseases; Baclofen; Benzodiazepines; Blood Proteins; Central Nervous System; Cerebrospinal Fluid Proteins; Electrodiagnosis; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Stiff-Person Syndrome | 1994 |
GABA transporters and GABAC-like receptors on catfish cone- but not rod-driven horizontal cells.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Chloride Channels; Crotonates; Electrophysiology; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Ictaluridae; Kainic Acid; Kinetics; Membrane Proteins; Membrane Transport Proteins; Muscimol; Organic Anion Transporters; Picrotoxin; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Stereoisomerism; Time Factors | 1994 |
Antitussive effects of GABAB agonists in the cat and guinea-pig.
Topics: Animals; Antitussive Agents; Baclofen; Capsaicin; Cats; Codeine; Cough; Dextromethorphan; Electromyography; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Irritants; Male; Organophosphorus Compounds; Respiratory Muscles | 1993 |
The influence of thalamic GABA transmission on the susceptibility of adult rats to flurothyl induced seizures.
Topics: Aminocaproates; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Bicuculline; Flurothyl; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Rats; Rats, Sprague-Dawley; Seizures; Synaptic Transmission; Thalamic Nuclei; Vigabatrin | 1993 |
Biphasic GABA-A receptor-mediated effect on the spontaneous activity of the circular layer in cat terminal ileum.
Topics: Animals; Atropine; Baclofen; Bicuculline; Cats; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Tetrodotoxin | 1993 |
Involvement of both GABAA and GABAB receptors in tonic inhibitory control of blood pressure at the rostral ventrolateral medulla of the rat.
Topics: Animals; Baclofen; Blood Pressure; Brain; Cardiovascular System; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 1993 |
gamma-Aminobutyric acid-induced elevation of intracellular calcium concentration in pituitary cells of neonatal rats.
Topics: Animals; Animals, Newborn; Baclofen; Calcium; Female; Fura-2; gamma-Aminobutyric Acid; In Vitro Techniques; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Potassium Chloride; Rats; Rats, Wistar; Receptors, GABA-A; Verapamil | 1993 |
GABAB receptor-mediated inhibition of forskolin-stimulated cyclic AMP accumulation in rat spinal cord.
Topics: Analgesics; Animals; Animals, Newborn; Baclofen; Capsaicin; Colforsin; Cyclic AMP; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord | 1993 |
Reduction of GABA inhibition in Purkinje and cerebellar nuclei neurons in climbing fibre deafferented cerebella of rat.
Topics: Animals; Baclofen; Cerebellar Nuclei; Denervation; Electrophysiology; gamma-Aminobutyric Acid; Iontophoresis; Microelectrodes; Muscimol; Nerve Fibers; Neurons; Neurons, Afferent; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 1993 |
Giant GABAB-mediated synaptic potentials induced by zinc in the rat hippocampus: paradoxical effects of zinc on the GABAB receptor.
Topics: Animals; Baclofen; Barium; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ions; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Synaptic Transmission; Zinc | 1993 |
GABAergic modulation of striatal cholinergic interneurons: an in vivo microdialysis study.
Topics: Acetylcholine; Analysis of Variance; Animals; Baclofen; Bicuculline; Corpus Striatum; gamma-Aminobutyric Acid; Interneurons; Kinetics; Male; Microdialysis; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Time Factors | 1994 |
Thienyl-GABA derivatives as specific baclofen agonists in the rat and cat spinal cord in vivo.
Topics: Animals; Baclofen; Cats; Electrophoresis; Evoked Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-B; Spinal Cord | 1993 |
Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons.
Topics: Analgesics; Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Homeostasis; In Vitro Techniques; Male; Naloxone; Nerve Fibers; Neurons; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Synapses | 1993 |
gamma-Aminobutyric acid is an inhibitory neurotransmitter restricting the release of luteinizing hormone-releasing hormone before the onset of puberty.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Macaca mulatta; Ovariectomy; Secretory Rate; Sexual Maturation; Statistics as Topic | 1994 |
GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra.
Topics: Animals; Baclofen; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Substantia Nigra | 1993 |
Effects of GABAergic drugs on ethanol-induced gastric lesions.
Topics: Animals; Baclofen; Bicuculline; Diazepam; Ethanol; GABA Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Hemorrhage; Indomethacin; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Valproic Acid | 1993 |
CGP 55845A: a potent antagonist of GABAB receptors in the CA1 region of rat hippocampus.
Topics: Animals; Baclofen; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Phosphinic Acids; Propanolamines; Rats; Receptors, GABA-B; Synapses | 1993 |
GABA induces Ca2+ transients in astrocytes.
Topics: Animals; Astrocytes; Baclofen; Bicuculline; Calcium; Cells, Cultured; Cerebral Cortex; Cytosol; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Nicotinic Acids; Nifedipine; Rats | 1993 |
Influence of GABA on neurons of the gustatory zone of the rat nucleus of the solitary tract.
Topics: Animals; Baclofen; Bicuculline; Brain Mapping; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Male; Medulla Oblongata; Membrane Potentials; Muscimol; Neurons; Perfusion; Rats; Taste; Tetrodotoxin | 1993 |
Excitatory and inhibitory responses mediated by GABAA and GABAB receptors in guinea pig distal colon.
Topics: Animals; Baclofen; Colon; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Nitroprusside; Receptors, GABA-A; Tetrodotoxin | 1993 |
Analysis of gamma-aminobutyric acidB receptor function in the in vitro and in vivo regulation of alpha-melanotropin-stimulating hormone secretion from melanotrope cells of Xenopus laevis.
Topics: alpha-MSH; Animals; Baclofen; Butylamines; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Homeostasis; In Vitro Techniques; Kinetics; Organophosphorus Compounds; Perfusion; Pituitary Gland, Posterior; Radioimmunoassay; Receptors, GABA-A; Xenopus laevis | 1993 |
Indications from Mn-quenching of Fura-2 fluorescence in melanotrophs that dopamine and baclofen close Ca channels that are spontaneously open but not those opened by high [K+]O; and that Cd preferentially blocks the latter.
Topics: Action Potentials; Animals; Baclofen; Cadmium; Calcium Channel Blockers; Calcium Channels; Dopamine; Fluorescence; Fura-2; gamma-Aminobutyric Acid; Male; Manganese; Nickel; Organophosphorus Compounds; Pertussis Toxin; Pituitary Gland; Potassium; Rats; Rats, Sprague-Dawley; Sodium Channels; Sulpiride; Tetrodotoxin; Virulence Factors, Bordetella | 1993 |
Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Animals; Baclofen; Barium; Binding Sites; Calcium; Calcium Channels; Cells, Cultured; Cerebellum; Cyclic AMP; Dihydropyridines; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamine; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Membrane Potentials; NAD; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1993 |
Identification of cannabinoid receptors in cultures of rat cerebellar granule cells.
Topics: Adenosine Diphosphate Ribose; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Baclofen; Cannabinoids; Cells, Cultured; Cerebellum; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; gamma-Aminobutyric Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Kinetics; Male; Mice; Mice, Neurologic Mutants; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Virulence Factors, Bordetella | 1993 |
Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.
Topics: Acetates; Amines; Amino Acids; Animals; Anticonvulsants; Baclofen; Binding Sites; Cell Membrane; Cerebral Cortex; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Rats; Receptors, GABA-A; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Spermidine; Spermine | 1993 |
The spinal GABA system modulates burst frequency and intersegmental coordination in the lamprey: differential effects of GABAA and GABAB receptors.
Topics: Animals; Baclofen; Bicuculline; Culture Techniques; Diazepam; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Lampreys; Locomotion; Motor Neurons; Muscimol; Muscles; N-Methylaspartate; Nerve Net; Neurons; Nipecotic Acids; Proline; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission | 1993 |
Effects of GABAB receptor agonists and antagonists on the bulbar respiratory network in cat.
Topics: Animals; Baclofen; Cats; Decerebrate State; Dizocilpine Maleate; Evoked Potentials; Extracellular Space; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Medulla Oblongata; Nerve Net; Organophosphorus Compounds; Plethysmography; Receptors, GABA-A; Respiration | 1993 |
Spontaneous cytosolic calcium pulsing detected in Xenopus melanotrophs: modulation by secreto-inhibitory and stimulant ligands.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Dopamine; Female; gamma-Aminobutyric Acid; Male; Melanocyte-Stimulating Hormones; Muscimol; Neuropeptide Y; Nickel; Periodicity; Pertussis Toxin; Pituitary Gland; Receptors, GABA-A; Virulence Factors, Bordetella; Xenopus laevis | 1993 |
GABA, THIP and baclofen inhibition of Purkinje cells and cerebellar nuclei neurons.
Topics: Animals; Baclofen; Cerebellar Nuclei; Dose-Response Relationship, Drug; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Neural Inhibition; Neurons; Purkinje Cells; Rats; Rats, Sprague-Dawley | 1993 |
Intraseptal injection of GABA and benzodiazepine receptor ligands alters high-affinity choline transport in the hippocampus.
Topics: Acetylcholinesterase; Animals; Baclofen; Brain; Carbolines; Chlordiazepoxide; Choline; Convulsants; Flumazenil; gamma-Aminobutyric Acid; Hippocampus; Injections; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
GABAB receptor inhibition of P-type Ca2+ channels in central neurons.
Topics: Animals; Baclofen; Calcium Channels; Electric Conductivity; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Kinetics; Mollusk Venoms; Neurons; omega-Agatoxin IVA; omega-Conotoxin GVIA; Purkinje Cells; Rats; Receptors, GABA-A; Spider Venoms; Spinal Cord | 1993 |
gamma-Aminobutyric acid (GABA) autoreceptors in rat cerebral cortex and spinal cord represent pharmacologically distinct subtypes of the GABAB receptor.
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Potassium; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptosomes | 1993 |
Differential effects of coexisting dopamine, GABA and NPY on alpha-MSH secretion from melanotrope cells of Xenopus laevis.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; alpha-MSH; Animals; Baclofen; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Isonicotinic Acids; Kinetics; Neuropeptide Y; Perfusion; Pituitary Gland; Radioimmunoassay; Xenopus laevis | 1993 |
Endogenous GABA release from rat striatal slices: effects of the GABAB receptor antagonist 2-hydroxy-saclofen.
Topics: Animals; Baclofen; Calcium; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Nipecotic Acids; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Tiagabine | 1993 |
Effects of post-training administration of (-)-baclofen and chlordiazepoxide on memory retention in ICRC Swiss mice: interactions with GABAA and GABAB receptor antagonists.
Topics: Animals; Baclofen; Chlordiazepoxide; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isomerism; Male; Memory; Mice; Mice, Inbred ICR; Motor Activity; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A | 1993 |
GABA receptor subtypes involved in the neuronal mechanisms of baroreceptor reflex in the nucleus tractus solitarii of rabbits.
Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; gamma-Aminobutyric Acid; Male; Neurons; Phenylephrine; Pressoreceptors; Rabbits; Receptors, GABA-A | 1993 |
GABAA receptor-induced inhibition of neuronal burst firing is weak in rat somatosensory cortex.
Topics: Animals; Baclofen; Flurazepam; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Somatosensory Cortex | 1993 |
[Responses mediated by GABAA and GABAB receptors on the somatic membrane of toad dorsal root ganglion neurones].
Topics: Action Potentials; Animals; Baclofen; Bufo bufo; Cell Membrane; gamma-Aminobutyric Acid; Ganglia, Spinal; In Vitro Techniques; Membrane Potentials; Neurons; Receptors, GABA-A | 1993 |
(+/-)Baclofen sensitive scopolamine-induced short-term memory deficits in mice.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Memory, Short-Term; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Receptors, GABA-A; Scopolamine | 1993 |
Pre- and postsynaptic GABAB receptors of rat neocortical neurons differ in their pharmacological properties.
Topics: Animals; Baclofen; Cerebral Cortex; Electric Stimulation; Feedback; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1993 |
In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: II. Inhibition by gamma-aminobutyric acid.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Choline; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Infusions, Parenteral; Kinetics; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors | 1993 |
Muscle cramp as the result of impaired GABA function--an electrophysiological and pharmacological observation.
Topics: Amyotrophic Lateral Sclerosis; Baclofen; Clomipramine; Diazepam; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Levodopa; Lidocaine; Male; Middle Aged; Motor Neurons; Muscle Cramp; Muscular Atrophy, Spinal; Nerve Block; Neural Conduction; Sensory Thresholds; Ulnar Nerve | 1993 |
Examination of the effects of cholecystokinin 26-33 and neuropeptide Y on responses of visual cortical neurons of the cat.
Topics: Animals; Baclofen; Cats; Cholecystokinin; Evoked Potentials, Visual; gamma-Aminobutyric Acid; Iontophoresis; Neural Conduction; Neurons; Neuropeptide Y; Photic Stimulation; Proglumide; Sincalide; Tachyphylaxis; Visual Cortex | 1993 |
Pharmacologically induced elements of the hunting and feeding behavior in the pteropod mollusk Clione limacina. I. Effects of GABA.
Topics: Animals; Baclofen; Bicuculline; Brain; Electrophysiology; Extremities; Feeding Behavior; Fluorescent Antibody Technique; gamma-Aminobutyric Acid; Ganglia; Immunoenzyme Techniques; Locomotion; Mollusca; Nerve Net; Neurons; Neurons, Efferent; Picrotoxin; Predatory Behavior; Tissue Embedding | 1993 |
Attenuation of hippocampal long-term potentiation by ethanol: a patch-clamp analysis of glutamatergic and GABAergic mechanisms.
Topics: Animals; Baclofen; Electrophysiology; Ethanol; gamma-Aminobutyric Acid; Glutamine; Granulocytes; Hippocampus; Male; Midazolam; Neuronal Plasticity; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Membrane properties and synaptic potentials of three types of neurone in rat lateral amygdala.
Topics: Action Potentials; Amino Acids; Amygdala; Animals; Baclofen; Culture Techniques; Electric Stimulation; Enkephalin, Methionine; gamma-Aminobutyric Acid; Membrane Potentials; Pentagastrin; Rats; Sincalide; Synapses; Synaptic Membranes | 1993 |
Response of locus coeruleus neurons to footshock stimulation is mediated by neurons in the rostral ventral medulla.
Topics: Animals; Baclofen; Basal Ganglia; Cadmium; Electroshock; gamma-Aminobutyric Acid; Lidocaine; Locus Coeruleus; Male; Manganese; Medulla Oblongata; Microinjections; Neurons; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Synapses | 1993 |
GABA-induced motility of spinal neuroblasts develops along a ventrodorsal gradient and can be mimicked by agonists of GABAA and GABAB receptors.
Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Chemotaxis; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Spinal Cord | 1995 |
Pharmacological characterization of pre- and postsynaptic GABAB receptors in the deep nuclei of rat cerebellar slices.
Topics: Animals; Baclofen; Cerebellar Nuclei; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurotransmitter | 1995 |
gamma-Aminobutyric acid stimulates electrolyte transport in the guinea pig ileum in vitro.
Topics: Analysis of Variance; Animals; Atropine; Autoradiography; Baclofen; Bicuculline; Biological Transport; Capsaicin; Electrolytes; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Intestinal Mucosa; Male; Neurons, Afferent; Parasympatholytics; Pyrilamine; Taurine | 1996 |
Input-output dependence reveals the components of GABAergic modulation in rat hippocampal CA3 in vivo.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Rats; Rats, Sprague-Dawley | 1995 |
GABA transport and calcium dynamics in horizontal cells from the skate retina.
Topics: Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Dantrolene; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Muscle Relaxants, Central; Nifedipine; Picrotoxin; Retina; Skates, Fish | 1995 |
[The effect of phenibut on formation of respiratory rhythm].
Topics: Animals; Baclofen; Cats; Female; GABA Modulators; gamma-Aminobutyric Acid; Hemodynamics; Male; Receptors, GABA; Respiration; Sodium Oxybate | 1995 |
GABAergic and glutaminergic modulation of centrally evoked arrhythmias in rats.
Topics: Animals; Arrhythmias, Cardiac; Baclofen; Brain; Cardiovascular System; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Glutamine; Injections, Intravenous; Injections, Intraventricular; Ketamine; Kynurenic Acid; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Synaptic Transmission | 1996 |
Additivity and non-additivity between dopamine-, norepinephrine-, carbachol- and GABA-stimulated GTPase activity.
Topics: Adrenergic Agonists; Adrenergic alpha-Antagonists; Animals; Baclofen; Carbachol; Corpus Striatum; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; GTP Phosphohydrolases; L Cells; Male; Mice; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Neurotransmitter | 1995 |
Activation of GABAB receptors at individual release boutons of the crayfish opener neuromuscular junction produces presynaptic inhibition.
Topics: Animals; Astacoidea; Baclofen; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neural Conduction; Neural Inhibition; Neuromuscular Junction; Picrotoxin; Presynaptic Terminals | 1996 |
Block of glutamate decarboxylase decreases GABAergic inhibition at the crayfish synapses: possible role of presynaptic metabotropic mechanisms.
Topics: 3-Mercaptopropionic Acid; Aminooxyacetic Acid; Animals; Astacoidea; Baclofen; Chloride Channels; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; In Vitro Techniques; Models, Neurological; Muscles; Nerve Fibers; Picrotoxin; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1996 |
Actions of the anticonvulsant agent 2-amino-4-phosphonobutyrate on the release of [3H]D-aspartate from rat forebrain slices.
Topics: Aminobutyrates; Animals; Anticonvulsants; Aspartic Acid; Baclofen; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Isomerism; Kynurenic Acid; Prosencephalon; Rats | 1996 |
Paired pulse facilitation of GABAergic IPSCs in ventral horn neurons in neonatal rat spinal cord.
Topics: Adenosine; Animals; Animals, Newborn; Anterior Horn Cells; Baclofen; Bicuculline; Calcium; Electric Stimulation; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Presynaptic; Spinal Cord; Synapses; Synaptic Transmission | 1996 |
Effects of central GABAB receptor modulation upon the milk ejection reflex in the rat.
Topics: Animals; Baclofen; Electric Stimulation; Electroencephalography; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Injections; Injections, Intraventricular; Microdialysis; Milk Ejection; Oxytocin; Rats; Rats, Wistar; Receptors, GABA-A; Supraoptic Nucleus | 1996 |
Extracellular K+ accumulations and synchronous GABA-mediated potentials evoked by 4-aminopyridine in the adult rat hippocampus.
Topics: 4-Aminopyridine; Animals; Baclofen; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; Potassium; Rats; Rats, Sprague-Dawley | 1996 |
Age-specific effects of baclofen on pentylenetetrazol-induced seizures in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Organophosphorus Compounds; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, GABA; Seizures | 1996 |
Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study.
Topics: 4-Aminobutyrate Transaminase; Acetates; Adult; Amines; Anticonvulsants; Baclofen; Calcium Channel Blockers; Cyclohexanecarboxylic Acids; Differential Threshold; Enzyme Inhibitors; Gabapentin; gamma-Aminobutyric Acid; Humans; Motor Cortex; Physical Stimulation; Transcranial Magnetic Stimulation; Vigabatrin | 1996 |
GABAB receptor-mediated responses in GABAergic projection neurones of rat nucleus reticularis thalami in vitro.
Topics: Animals; Baclofen; Electrophysiology; Evoked Potentials; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neural Pathways; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Presynaptic; Thalamic Nuclei | 1996 |
Modulation of respiratory rhythm in vitro: role of Gi/o protein-mediated mechanisms.
Topics: Analgesics; Animals; Baclofen; Clonidine; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Rats; Respiration; Serotonin | 1996 |
The vigilance promoting drug modafinil increases dopamine release in the rat nucleus accumbens via the involvement of a local GABAergic mechanism.
Topics: Analysis of Variance; Animals; Baclofen; Benzhydryl Compounds; Central Nervous System Stimulants; Dopamine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Modafinil; Muscimol; Nipecotic Acids; Nucleus Accumbens; Rats; Rats, Sprague-Dawley | 1996 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
GABA, glutamate and substance P-like immunoreactivity release: effects of novel GABAB antagonists.
Topics: Animals; Baclofen; Benzoates; Benzylamines; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Isonicotinic Acids; Male; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Nerve Roots; Stereoisomerism; Substance P | 1996 |
GABAergic inhibitory inputs to subfornical organ neurons in rat slice preparations.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Subfornical Organ | 1995 |
GABA-induced responses in electrophysiologically characterized neurons within the rat rostro-ventrolateral medulla in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Synapses | 1996 |
Multiple postsynaptic actions of GABA via GABAB receptors on CA1 pyramidal cells of rat hippocampal slices.
Topics: Animals; Baclofen; Barium; Cesium; Chlorides; Electric Conductivity; Electrodes; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Potassium Chloride; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 1996 |
Desensitization by cyclic AMP-dependent protein kinase of GABAB receptor expressed in Xenopus oocytes.
Topics: Animals; Baclofen; Bicuculline; Bucladesine; Cerebellum; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression; Isoquinolines; Membrane Potentials; Oocytes; Rats; Receptors, GABA-B; RNA; Xenopus laevis | 1995 |
GABAB receptors negatively regulate transcription in cerebellar granular neurons through cyclic AMP responsive element binding protein-dependent mechanisms.
Topics: Animals; Baclofen; Calcium; Cerebellum; Cyclic AMP; gamma-Aminobutyric Acid; Rats; Rats, Wistar; Receptors, GABA-B; Transcription, Genetic | 1996 |
Growth hormone response to baclofen: a comparison of 10-mg and 20-mg doses in healthy men.
Topics: Adult; Baclofen; Depressive Disorder; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hypothalamus; Male; Middle Aged; Muscle Relaxants, Central | 1996 |
Influence of GABAergic mechanisms on baroreceptor inputs to nucleus tractus solitarii of rats.
Topics: Afferent Pathways; Animals; Baclofen; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Male; Muscimol; Neurons; Pressoreceptors; Rats; Rats, Wistar; Solitary Nucleus | 1996 |
Inhibition of calcium spikes by gamma-amino-butyric acid in the neurons of Lymnaea stagnalis L.
Topics: Action Potentials; Animals; Baclofen; Calcium; GABA Agonists; gamma-Aminobutyric Acid; Ion Transport; Lymnaea; Muscimol; Neurons; Pentylenetetrazole; Pertussis Toxin; Receptors, GABA-B; Virulence Factors, Bordetella | 1995 |
Estrogen rapidly attenuates a GABAB response in hypothalamic neurons.
Topics: Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Estradiol; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hypothalamus; Neurons; Potassium Channels; Receptors, GABA; Receptors, Opioid, mu | 1996 |
Effects of spinal cord stimulation on touch-evoked allodynia involve GABAergic mechanisms. An experimental study in the mononeuropathic rat.
Topics: Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Spinal; Male; Muscimol; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 1996 |
Effects of gamma-aminobutyric acid (GABA) agonists and GABA uptake inhibitors on pharmacosensitive and pharmacoresistant epileptiform activity in vitro.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Entorhinal Cortex; Epilepsy; Female; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Muscimol; Neurons; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Proline; Rats; Rats, Wistar; Tiagabine | 1996 |
Release of taurine and its effects on release of neurotransmitter amino acids in rat cerebral cortex.
Topics: Animals; Aspartic Acid; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Chromatography, High Pressure Liquid; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Male; Membrane Potentials; Potassium Chloride; Rats; Rats, Wistar; Spectrometry, Fluorescence; Synaptosomes; Taurine; Time Factors | 1996 |
Differential actions of serotonin, mediated by 5-HT1B and 5-HT2C receptors, on GABA-mediated synaptic input to rat substantia nigra pars reticulata neurons in vitro.
Topics: Animals; Baclofen; Electric Conductivity; gamma-Aminobutyric Acid; Neurons; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Substantia Nigra; Synapses; Synaptic Transmission | 1996 |
Interaction of taurine on baclofen intestinal absorption: a nonlinear mathematical treatment using differential equations to describe kinetic inhibition models.
Topics: Animals; Baclofen; beta-Alanine; gamma-Aminobutyric Acid; Intestinal Absorption; Kinetics; Leucine; Male; Models, Chemical; Muscle Relaxants, Central; Rats; Rats, Wistar; Taurine | 1996 |
Effects of gamma-aminobutyric acid agonists on the isolated perfused rat kidney.
Topics: Animals; Baclofen; Bicuculline; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Kidney; Male; Muscimol; Perfusion; Rats; Rats, Wistar | 1996 |
Inhibition of transmitter release shortens the duration of the excitatory synaptic current at a calyceal synapse.
Topics: Animals; Baclofen; Brain Stem; Chick Embryo; GABA Agonists; gamma-Aminobutyric Acid; Neurotransmitter Agents; Synapses; Synaptic Transmission | 1996 |
Effects of GABA and glycine receptor antagonists on the activity and PAG-induced inhibition of rat dorsal horn neurons.
Topics: Analysis of Variance; Animals; Baclofen; Bicuculline; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Microdialysis; Muscimol; Neurons; Periaqueductal Gray; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Skin; Spinal Cord; Strychnine; Time Factors | 1996 |
Relation of the [3H] gamma-hydroxybutyric acid (GHB) binding site to the gamma-aminobutyric acidB (GABAB) receptor in rat brain.
Topics: Animals; Autoradiography; Baclofen; Benzocycloheptenes; Binding Sites; Brain; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guanosine Triphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Seizures; Sodium Oxybate; Stereoisomerism | 1996 |
Anoxia blocks the presynaptic control of GABA release at inhibitory terminals in the rat hippocampus.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Animals; Baclofen; Cell Hypoxia; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Male; Neurons; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 1996 |
GABAergic modulation of optic nerve-evoked field potentials in the rat suprachiasmatic nucleus.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Optic Nerve; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus | 1995 |
Analysis of the kinetics of synaptic inhibition points to a reduction in GABA release in area CA1 of the genetically epileptic mouse, El.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Electric Stimulation; Epilepsy; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Mice; Mice, Mutant Strains; Neural Inhibition; Nipecotic Acids; Receptors, GABA; Species Specificity; Synaptic Transmission; Tiagabine | 1996 |
N-ethylmaleimide blocks depolarization-induced suppression of inhibition and enhances GABA release in the rat hippocampal slice in vitro.
Topics: Analysis of Variance; Animals; Baclofen; Ethylmaleimide; Evoked Potentials; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Isoxazoles; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA | 1997 |
GABAB receptor-mediated inhibition of tetrodotoxin-resistant GABA release in rodent hippocampal CA1 pyramidal cells.
Topics: Animals; Baclofen; Calcium; Drug Resistance; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Kinetics; Potassium; Protein Kinase C; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, GABA-B; Synaptic Transmission; Tetrodotoxin | 1997 |
GABAergic characteristics of transcallosal activity of cat motor cortical neurons.
Topics: Animals; Baclofen; Bicuculline; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Motor Cortex; Organophosphorus Compounds | 1996 |
GABAA receptor-mediated K(+)-evoked GABA release from globus pallidus--analysis using microdialysis.
Topics: Animals; Baclofen; Dinucleoside Phosphates; GABA Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Muscimol; Nipecotic Acids; Potassium Chloride; Proline; Rats; Rats, Wistar; Receptors, GABA-A | 1997 |
Effect of continuous infusion of GABA and baclofen on gastric secretion in anaesthetised rats.
Topics: Animals; Anti-Ulcer Agents; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Gastric Acid; Gastric Mucosa; Infusions, Intravenous; Male; Pepsin A; Rats | 1996 |
Both GABAA and GABAB receptors participate in suppression of [CA2+]i pulsing in toad melanotrophs.
Topics: Animals; Baclofen; Calcium; Cells, Cultured; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Pertussis Toxin; Pituitary Gland; Receptors, GABA-A; Receptors, GABA-B; Virulence Factors, Bordetella; Xenopus laevis | 1997 |
[Rhythmic circulatory dysregulation in stiff man syndrome].
Topics: Autonomic Nervous System; Baclofen; Blood Pressure; Cardiovascular System; Female; GABA Agonists; gamma-Aminobutyric Acid; Heart Rate; Hemodynamics; Humans; Injections, Spinal; Middle Aged; Spinal Cord; Stiff-Person Syndrome | 1996 |
Binding characteristics of gamma-hydroxybutyric acid as a weak but selective GABAB receptor agonist.
Topics: Animals; Anticonvulsants; Baclofen; Binding, Competitive; Brain Chemistry; Ethosuximide; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Oxybate; Valproic Acid | 1997 |
GABAergic drugs and sexual motivation, receptivity and exploratory behaviors in the female rat.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Exploratory Behavior; Female; gamma-Aminobutyric Acid; Male; Nicotinic Acids; Rats; Rats, Wistar; Sexual Behavior, Animal | 1997 |
In vitro capacitating effect of gamma-aminobutyric acid in ram spermatozoa.
Topics: Acrosome; Analysis of Variance; Animals; Baclofen; Calcimycin; Chlortetracycline; Dose-Response Relationship, Drug; Exocytosis; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neuroprotective Agents; Pregnanolone; Prostate-Specific Antigen; Receptors, GABA-A; Receptors, GABA-B; Sheep; Sperm Capacitation; Spermatozoa | 1997 |
Specific action of GABAB ligands on the temperature sensitivity of hypothalamic neurons.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Body Temperature Regulation; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hot Temperature; Hypothalamus, Anterior; In Vitro Techniques; Male; Neurons; Preoptic Area; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Thermoreceptors | 1997 |
Diazepam-insensitive GABAA receptors on postnatal spiral ganglion neurones in culture.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Carbolines; Cells, Cultured; Convulsants; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-A; Spiral Ganglion; Zinc | 1997 |
Pharmacologically distinct GABAB receptors that mediate inhibition of GABA and glutamate release in human neocortex.
Topics: Aged; Amino Acids; Baclofen; Calcium; Cerebral Cortex; Female; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; In Vitro Techniques; Male; Middle Aged; Potassium; Receptors, GABA-B; Synaptosomes | 1997 |
Heterogeneity in use-dependent depression of inhibitory postsynaptic potentials in the rat neostriatum in vitro.
Topics: Animals; Baclofen; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neostriatum; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-B; Synapses | 1997 |
Neuronal regulation of astrocyte morphology in vitro is mediated by GABAergic signaling.
Topics: Animals; Animals, Newborn; Astrocytes; Baclofen; Bicuculline; Cell Adhesion; Cells, Cultured; Coculture Techniques; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Isoxazoles; Muscimol; Neurons; Rats; Rats, Wistar; Signal Transduction; Sodium Channel Blockers; Tetrodotoxin; Time Factors | 1997 |
GABA in the nucleus accumbens shell participates in the central regulation of feeding behavior.
Topics: Animals; Baclofen; Eating; Enzyme Inhibitors; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Nucleus Accumbens; Proline; Rats; Rats, Sprague-Dawley; Vigabatrin | 1997 |
GABAB receptor-mediated inhibition of spontaneous inhibitory synaptic currents in rat midbrain culture.
Topics: Animals; Baclofen; Cadmium; Calcium Channel Blockers; Cells, Cultured; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Mesencephalon; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channels; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Channels; Synapses; Tetrodotoxin; Virulence Factors, Bordetella | 1997 |
OFF pathway is preferentially suppressed by the activation of GABA(A) receptors in carp retina.
Topics: Animals; Baclofen; Bicuculline; Carps; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neural Pathways; Receptors, GABA-A; Retina | 1997 |
Two metabotropic gamma-aminobutyric acid receptors differentially modulate calcium currents in retinal ganglion cells.
Topics: Action Potentials; Ambystoma; Animals; Baclofen; Calcium; Calcium Channels; Crotonates; Electric Conductivity; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Receptors, GABA-B; Retinal Ganglion Cells; Second Messenger Systems | 1997 |
GABAA receptor-mediated IPSCs in rat thalamic sensory nuclei: patterns of discharge and tonic modulation by GABAB autoreceptors.
Topics: Animals; Autoreceptors; Baclofen; Cadmium; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Interneurons; Isonicotinic Acids; Male; Membrane Potentials; Organ Culture Techniques; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Tetrodotoxin; Thalamic Nuclei | 1997 |
Effects of gamma-aminobutyric acid on human sperm motility and hyperactivation.
Topics: Baclofen; Bicuculline; Cyclic AMP; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Progesterone; Semen; Sperm Motility | 1996 |
Involvement of supraspinal GABA-ergic systems in clonidine-induced antinociception in the tail-pinch test in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Baclofen; Bicuculline; Clonidine; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Pain; Picrotoxin; Receptors, GABA; Tail | 1997 |
Inhibitory effect of baclofen on GABA-induced depolarization and GABA-activated current in primary sensory neurons.
Topics: Animals; Baclofen; Electric Conductivity; Electrophysiology; Female; GABA Agonists; gamma-Aminobutyric Acid; Isonicotinic Acids; Male; Muscimol; Neurons, Afferent; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Time Factors | 1997 |
GABAergic control of the firing pattern of substantia nigra dopaminergic neurons.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Kinetics; Muscimol; Neurons; Rats; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra | 1998 |
Modulation of intrinsic circuits by serotonin 5-HT3 receptors in developing ferret visual cortex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Ferrets; gamma-Aminobutyric Acid; Indoles; Ligands; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Pyridinium Compounds; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, GABA-A; Receptors, GABA-B; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses; Synaptic Transmission; Tetrodotoxin; Time Factors; Tropisetron; Virulence Factors, Bordetella; Visual Cortex | 1997 |
Functional properties of perigeniculate inhibition of dorsal lateral geniculate nucleus thalamocortical neurons in vitro.
Topics: Acetazolamide; Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Convulsants; Electrophysiology; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Male; Membrane Potentials; Neural Inhibition; Neural Pathways; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Thalamic Nuclei | 1997 |
Inhibitory interactions between perigeniculate GABAergic neurons.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Axons; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Excitatory Postsynaptic Potentials; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Male; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Different roles for GABAA and GABAB receptors in visual processing in the rat superior colliculus.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Iontophoresis; Organophosphorus Compounds; Photic Stimulation; Rats; Receptors, GABA-A; Receptors, GABA-B; Superior Colliculi; Vision, Ocular; Visual Fields | 1997 |
How opioids inhibit GABA-mediated neurotransmission.
Topics: Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Aspirin; Baclofen; Enkephalin, Methionine; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Narcotics; Periaqueductal Gray; Phospholipases A; Phospholipases A2; Potassium; Potassium Channel Blockers; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Opioid, mu; Second Messenger Systems; Synapses; Synaptic Transmission | 1997 |
Presynaptic GABAB and adenosine A1 receptors regulate synaptic transmission to rat substantia nigra reticulata neurones.
Topics: Adenosine; Animals; Baclofen; Electrophysiology; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Receptors, Purinergic P1; Substantia Nigra; Synaptic Transmission; Xanthines | 1997 |
Inhibitory cholinergic control of endogenous GABA release from electrically stimulated cortical slices and K(+)-depolarized synaptosomes.
Topics: Acetylcholine; Animals; Baclofen; Calcium; Cerebral Cortex; Culture Media; Electric Stimulation; Enzyme Inhibitors; Ethanolamines; Female; gamma-Aminobutyric Acid; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Nipecotic Acids; Potassium; Synaptosomes; Tetrodotoxin | 1997 |
Intrahippocampal GMP administration improves inhibitory avoidance performance through GABAergic and glutamatergic mechanisms in rats.
Topics: Animals; Avoidance Learning; Baclofen; Cyclic GMP; Dizocilpine Maleate; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microinjections; Muscimol; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate | 1997 |
Presynaptic GABAB autoreceptor modulation of P/Q-type calcium channels and GABA release in rat suprachiasmatic nucleus neurons.
Topics: Animals; Animals, Newborn; Autoreceptors; Baclofen; Calcium Channels; Calcium Channels, N-Type; Cells, Cultured; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Neurons; Patch-Clamp Techniques; Pertussis Toxin; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Presynaptic; Suprachiasmatic Nucleus; Virulence Factors, Bordetella | 1998 |
Age-related development of gamma-aminobutyric acid (GABA)B receptor functions in various brain regions of spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Aging; Animals; Baclofen; Brain; Corpus Striatum; Cyclic AMP; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Hypertension; Hypothalamus; Isoindoles; Male; Mesencephalon; Naphthyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA; Spiro Compounds | 1998 |
Ontogenesis of presynaptic GABAB receptor-mediated inhibition in the CA3 region of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Baclofen; Calcium; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Organophosphorus Compounds; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-B; Synaptic Transmission; Tiagabine | 1998 |
Modulation of calcium by inhibitory systems in the developing auditory midbrain.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Aging; Animals; Auditory Pathways; Baclofen; Bicuculline; Brain; Calcium; Electric Stimulation; Evoked Potentials; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Inferior Colliculi; Membrane Potentials; Mesencephalon; Muscimol; Neurons; Reaction Time; Receptors, GABA-A; Receptors, GABA-B | 1998 |
Functional organization of rat olfactory bulb glomeruli revealed by optical imaging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Male; N-Methylaspartate; Olfactory Bulb; Organ Culture Techniques; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Tetrodotoxin | 1998 |
Modulation of GAP-43 mRNA by GABA and glutamate in cultured cerebellar granule cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Different GABA-receptor types are involved in the 5-HT-induced antinociception at the spinal level: a behavioral study.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA; Serotonin; Spinal Cord | 1998 |
Effects of the neurosteroid dehydroepiandrosterone sulfate on medial vestibular nucleus neurons.
Topics: Animals; Baclofen; Cats; Dehydroepiandrosterone Sulfate; Electrophysiology; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Rotation; Vestibular Nuclei | 1998 |
Regulation of neurokinin-1 receptor expression by GABA(B) receptor agonists.
Topics: Animals; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Male; Organophosphonates; Pain Measurement; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; RNA, Messenger; Spinal Cord | 1998 |
Measurement of receptor-mediated functional activation of G proteins in postmortem human brain membranes.
Topics: Aged; Aged, 80 and over; Baclofen; Binding, Competitive; Brain; Cadaver; Female; GABA Agonists; gamma-Aminobutyric Acid; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Hydrolysis; Magnesium Chloride; Male; Membranes; Middle Aged; Receptors, GABA-B | 1998 |
A developmental shift from GABAergic to glycinergic transmission in the central auditory system.
Topics: Aging; Animals; Auditory Pathways; Baclofen; Brain; Electric Conductivity; GABA Agonists; gamma-Aminobutyric Acid; Gerbillinae; Glycine; Immunohistochemistry; Neural Inhibition; Neurons; Patch-Clamp Techniques; Receptors, GABA-A; Receptors, Glycine; Synaptic Transmission; Tissue Distribution | 1998 |
Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure.
Topics: Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Helium; High Pressure Neurological Syndrome; Male; Motor Activity; Muscimol; Myoclonus; Nipecotic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, GABA; Substantia Nigra; Synaptic Transmission; Time Factors; Vigabatrin | 1998 |
Effect of spinal cord stimulation on tactile hypersensitivity in mononeuropathic rats is potentiated by simultaneous GABA(B) and adenosine receptor activation.
Topics: Adenosine; Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hindlimb; Hyperesthesia; Male; Phosphinic Acids; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Sciatic Nerve; Sensory Thresholds; Spinal Cord; Theophylline | 1998 |
GABAergic modulation of ventral pallidal dopamine release studied by in vivo microdialysis in the freely moving rat.
Topics: Animals; Baclofen; Cocaine; Dopamine; Dopamine Uptake Inhibitors; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Microdialysis; Picrotoxin; Piperazines; Rats; Rats, Wistar | 1998 |
Corelease of two fast neurotransmitters at a central synapse.
Topics: Animals; Baclofen; Bicuculline; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; In Vitro Techniques; Interneurons; Motor Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Receptors, Glycine; Spinal Cord; Strychnine; Synaptic Transmission; Synaptic Vesicles | 1998 |
Role of GABA receptors in the bronchial response: studies in sensitized guinea-pigs.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Bronchi; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Ovalbumin; Trachea | 1998 |
GABAergic inhibition of hiccup-like reflex induced by electrical stimulation in medulla of cats.
Topics: Animals; Baclofen; Cats; Cholera Toxin; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Hiccup; Medulla Oblongata; Neural Inhibition; Pons; Receptors, GABA-A; Receptors, GABA-B; Reflex, Abnormal; Respiration | 1998 |
GABAergic input to cholinergic nucleus basalis neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Choline O-Acetyltransferase; Excitatory Postsynaptic Potentials; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; Immunohistochemistry; In Vitro Techniques; Muscimol; Neurons; Prosencephalon; Receptors, GABA-A; Receptors, GABA-B; Substantia Innominata; Synaptic Transmission | 1998 |
GABAergic effects on nucleus tractus solitarius neurons receiving gastric vagal inputs.
Topics: Animals; Animals, Newborn; Baclofen; Brain Stem; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Stomach; Vagus Nerve | 1998 |
Mechanisms underlying the enhancement of excitatory synaptic transmission in basolateral amygdala neurons of the kindling rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Baclofen; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1998 |
Modulation of spinal pain mechanisms by spinal cord stimulation and the potential role of adjuvant pharmacotherapy.
Topics: Adenosine; Animals; Baclofen; Behavior, Animal; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Models, Animal; Electric Stimulation Therapy; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male; Pain; Pain Management; Pain Threshold; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Purinergic P1; Spinal Cord; Touch; Treatment Outcome | 1997 |
Opioid inhibition of hippocampal interneurons via modulation of potassium and hyperpolarization-activated cation (Ih) currents.
Topics: Analgesics; Analgesics, Opioid; Animals; Baclofen; Barium; Cardiovascular Agents; Cations; Cell Size; Cells, Cultured; Cesium; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Interneurons; Male; Membrane Potentials; Potassium; Potassium Channels; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu | 1998 |
[ETICS Study: Empirical therapy of idiopathic chronic singultus].
Topics: Acetates; Aged; Aged, 80 and over; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Omeprazole; Treatment Outcome | 1998 |
Effect of GABA and baclofen on gastric mucosal protective factors.
Topics: Animals; Anti-Ulcer Agents; Baclofen; Female; GABA Agonists; gamma-Aminobutyric Acid; Gastric Mucosa; Male; Rats | 1998 |
Co-localized neuropeptide Y and GABA have complementary presynaptic effects on sensory synaptic transmission.
Topics: Animals; Baclofen; Female; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Glutamine; Immunohistochemistry; Intracellular Fluid; Lampreys; Male; Neurons, Afferent; Neuropeptide Y; Presynaptic Terminals; Receptors, Neuropeptide Y; Spinal Cord; Synaptic Transmission | 1998 |
Spinal inputs from lateral columns to reticulospinal neurons in lampreys.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Brain Stem; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Isotonic Solutions; Lampreys; Locomotion; Magnesium; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurotransmitter Agents; Ringer's Solution; Spinal Cord; Synaptic Transmission | 1998 |
GABA excites immature CA3 pyramidal cells through bicuculline-sensitive and -insensitive chloride-dependent receptors.
Topics: Animals; Animals, Newborn; Baclofen; Bicuculline; Chloride Channels; Culture Techniques; Evoked Potentials; gamma-Aminobutyric Acid; Kynurenic Acid; Nipecotic Acids; Patch-Clamp Techniques; Picrotoxin; Proline; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, GABA-B; Zinc | 1998 |
Effects of intravenous general anesthetics on [3H]GABA release from rat cortical synaptosomes.
Topics: Aminobutyrates; Anesthesia, General; Anesthetics, Intravenous; Animals; Baclofen; Bicuculline; Calcium; Cerebral Cortex; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Nerve Endings; Nipecotic Acids; Picrotoxin; Potassium Chloride; Proline; Propofol; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Synaptic Transmission; Synaptosomes; Tritium | 1998 |
Seizure sensitivity and GABAergic modulation of ethanol sensitivity in selectively bred FAST and SLOW mouse lines.
Topics: Animals; Baclofen; Ethanol; GABA Modulators; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Seizures; Species Specificity | 1998 |
Alcoholism abolishes the gamma-aminobutyric acid (GABA)ergic control of GH secretion in humans.
Topics: Adult; Alcoholism; Baclofen; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Human Growth Hormone; Humans; Kinetics; Male; Middle Aged; Valproic Acid | 1998 |
[Characteristics of human lymphocyte benzodiazepine receptors].
Topics: Adult; Baclofen; Benzodiazepinones; Binding, Competitive; Diazepam; Flumazenil; GABA Agonists; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Ligands; Lymphocytes; Male; Receptors, GABA-A | 1998 |
GABA(A) receptor modulates the activity of inner hair cell afferents in guinea pig cochlea.
Topics: Acetylcholine; Action Potentials; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Baclofen; Bicuculline; Cochlea; Electrophysiology; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Hair Cells, Auditory, Inner; Iontophoresis; Muscimol; N-Methylaspartate; Receptors, GABA-A | 1998 |
Receptor subtype specific effects of GABA agonists on neurons receiving aortic depressor nerve inputs within the nucleus of the solitary tract.
Topics: Animals; Aorta; Autonomic Nervous System; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Iontophoresis; Male; Membrane Potentials; Muscimol; Neurons; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Synapses; Synaptic Transmission | 1998 |
Inhibition evoked from primary afferents in the electrosensory lateral line lobe of the weakly electric fish (Apteronotus leptorhynchus).
Topics: Animals; Baclofen; Electric Fish; Electric Stimulation; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Iontophoresis; Male; Neurons, Afferent; Peripheral Nervous System; Pyramidal Cells; Sense Organs; Synapses | 1998 |
Exacerbation of cold restraint-induced gastric ulcer by GABA in mice.
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Baclofen; Bicuculline; Cold Temperature; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gastric Mucins; Male; Mice; Muscarinic Antagonists; Phentolamine; Stomach Ulcer; Stress, Physiological | 1996 |
GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord.
Topics: Animals; Autoreceptors; Baclofen; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord; Synaptosomes | 1998 |
Synaptic inhibition in the isolated respiratory network of neonatal rats.
Topics: Action Potentials; Animals; Animals, Newborn; Anti-Bacterial Agents; Baclofen; Bicarbonates; Bicuculline; Carbon Dioxide; Chloride Channel Agonists; Chloride Channels; Chlorides; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glycine Agents; Gramicidin; Medulla Oblongata; Microdialysis; Muscimol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Receptors, GABA-B; Respiration; Strychnine; Synapses; Tetrodotoxin | 1998 |
GABAergic effects on the depressor responses elicited by stimulation of central nucleus of the amygdala.
Topics: Amygdala; Animals; Baclofen; Bicuculline; Blood Pressure; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Male; Microinjections; Neurons; Rats; Rats, Wistar | 1999 |
Effects of GABA on acutely isolated neurons from the gustatory zone of the rat nucleus of the solitary tract.
Topics: Animals; Baclofen; Bicuculline; Cell Membrane; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Muscimol; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Solitary Nucleus | 1998 |
A powerful GABA(B) receptor-mediated inhibition of GABAergic neurons in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; In Situ Hybridization, Fluorescence; In Vitro Techniques; Neural Inhibition; Neurons; Organophosphorus Compounds; Receptors, GABA-B | 1998 |
GABAA and GABAB modulations of synaptic transmission between L1-L2 locomotor network and the motoneurons in the newborn rat isolated spinal cord.
Topics: Animals; Animals, Newborn; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Locomotion; Motor Neurons; Muscimol; Oligopeptides; Organ Culture Techniques; Rats; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Spinal Cord; Synaptic Transmission | 1998 |
Neurite outgrowth-regulating properties of GABA and the effect of serum on mouse spinal cord neurons in culture.
Topics: Animals; Baclofen; Cell Movement; Cell Size; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Growth Cones; Mice; Mice, Inbred BALB C; Microscopy, Phase-Contrast; Muscimol; Neurites; Spinal Cord | 1998 |
Substance P release in the dorsal horn assessed by receptor internalization: NMDA receptors counteract a tonic inhibition by GABA(B) receptors.
Topics: Animals; Baclofen; Dizocilpine Maleate; Down-Regulation; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Inhibition; Organ Culture Techniques; Rats; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P | 1999 |
Presynaptic GABAergic control of the locomotor drive in the isolated spinal cord of neonatal rats.
Topics: Animals; Animals, Newborn; Baclofen; Electrophysiology; Excitatory Amino Acid Agonists; Free Radical Scavengers; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Membrane Potentials; Mephenesin; Muscimol; Muscle Relaxants, Central; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Spinal Cord; Tetrodotoxin | 1999 |
Neuropeptide Y blocks GABAB-induced phase-shifts of the suprachiasmatic circadian clock in vitro.
Topics: Animals; Baclofen; Circadian Rhythm; Dose-Response Relationship, Drug; GABA Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Suprachiasmatic Nucleus | 1999 |
Carbamazepine facilitates effects of GABA on rat hippocampus slices.
Topics: Animals; Anticonvulsants; Baclofen; Carbamazepine; Evoked Potentials; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1997 |
Evaluation of 3-aminopropanesulphonamide analogues of GABA as antagonists at GABA(B) receptors in peripheral and central preparations.
Topics: Animals; Baclofen; Drug Interactions; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Neocortex; Rats; Rats, Sprague-Dawley; Sulfonamides | 1999 |
Distinct responses of osphradial neurons to chemical stimuli and neurotransmitters in Lymnaea stagnalis L.
Topics: Acetylcholine; Action Potentials; Animals; Aspartic Acid; Baclofen; FMRFamide; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Hexamethonium; Lymnaea; Neurons, Afferent; Neurotransmitter Agents; Nicotinic Antagonists; Patch-Clamp Techniques; Serotonin; Sodium Chloride; Stimulation, Chemical; Tetraethylammonium | 1999 |
Effects of CCK antagonists on GABA mechanism-induced antinociception in the formalin test.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Baclofen; Dose-Response Relationship, Drug; Formaldehyde; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Isoxazoles; Male; Mice; Morphine; Pain; Pain Measurement; Receptors, Cholecystokinin | 1999 |
Role of presynaptic L-type Ca2+ channels in GABAergic synaptic transmission in cultured hippocampal neurons.
Topics: Animals; Baclofen; Calcium; Calcium Channels; Cells, Cultured; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetany | 1999 |
The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dentate Gyrus; Electric Stimulation; GABA Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 1999 |
Comparison of gamma-aminobutyric acid effects in different parts of the cat ileum.
Topics: Acetylcholinesterase; Animals; Atropine; Baclofen; Bicuculline; Cats; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ileum; In Vitro Techniques; Male; Muscimol; Muscle Contraction; Tetrodotoxin | 1999 |
Tiagabine antinociception in rodents depends on GABA(B) receptor activation: parallel antinociception testing and medial thalamus GABA microdialysis.
Topics: Abdomen; Animals; Baclofen; Constriction, Pathologic; Dose-Response Relationship, Drug; Escape Reaction; Extracellular Space; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Microdialysis; Naloxone; Narcotic Antagonists; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Nociceptors; Organophosphorus Compounds; Pain; Pain Measurement; Pain Threshold; Psychomotor Performance; Receptors, GABA-B; Thalamus; Tiagabine | 1999 |
Cholinergic and GABAergic regulation of nitric oxide synthesis in the guinea pig ileum.
Topics: Animals; Baclofen; Bicuculline; Cholinergic Agonists; Cholinergic Antagonists; Citrulline; Egtazic Acid; Electric Stimulation; Female; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Isometric Contraction; Male; Mecamylamine; Muscimol; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitroarginine; Oxotremorine; Scopolamine; Tetrodotoxin; Tubocurarine | 1999 |
Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Nerve Degeneration; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Substantia Nigra | 1999 |
Activation of peripheral GABAA receptors inhibits temporomandibular joint-evoked jaw muscle activity.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electromyography; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Masseter Muscle; Motor Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Temporomandibular Joint | 1999 |
Antagonism of GABA(B) receptors by morpholino-2-acetic acid derivatives Sch 54679 and Sch 51324 in rat brain.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Morpholines; Neocortex; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Oximes; Rats; Rats, Sprague-Dawley; Tritium | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Clonidine; Dextromethorphan; Drug Interactions; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Ketamine; Mice; Muscimol; N-Methylaspartate; Picrotoxin; Receptors, GABA; Receptors, Glutamate; Seizures; Theophylline | 1999 |
Gamma-aminobutyric acid (GABA) A and B receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone.
Topics: Acrosome; Analysis of Variance; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Progesterone; Prospective Studies; Receptors, GABA-A; Receptors, GABA-B | 1999 |
Physiological and morphological correlates of presynaptic inhibition in primary afferents of the lamprey spinal cord.
Topics: Afferent Pathways; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Barium; Cadmium; Calcium Channels; Cell Membrane; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Lampreys; Membrane Potentials; Motor Neurons; Nerve Fibers; Neurons; Neurons, Afferent; Patch-Clamp Techniques; Presynaptic Terminals; Species Specificity; Spinal Cord; Synapses | 1999 |
N-type calcium channels and their regulation by GABAB receptors in axons of neonatal rat optic nerve.
Topics: Action Potentials; Adenosine; Animals; Animals, Newborn; Axons; Baclofen; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; GABA Agents; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Neuroglia; Optic Nerve; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Sodium-Calcium Exchanger | 1999 |
kappa- and mu-opioids reverse the somatostatin inhibition of Ca2+ currents in ciliary and dorsal root ganglion neurons.
Topics: Animals; Artifacts; Baclofen; Binding Sites; Calcium; Calcium Channels; Chick Embryo; Cytosol; gamma-Aminobutyric Acid; Ganglia, Parasympathetic; Ganglia, Spinal; GTP-Binding Proteins; Ion Channel Gating; Narcotics; Neurons; Norepinephrine; Patch-Clamp Techniques; Phosphorylation; Potassium Channels; Receptors, Opioid, kappa; Receptors, Opioid, mu; Signal Transduction; Somatostatin | 1999 |
Inhibitory influences on receptive field size in the dorsal column nuclei.
Topics: Animals; Baclofen; Bicuculline; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Male; Neural Inhibition; Neurons; Rats; Rats, Sprague-Dawley; Spinal Cord | 1999 |
GABA-Induced Cl- current in cultured embryonic human dorsal root ganglion neurons.
Topics: Adult; Baclofen; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Chloride Channels; Convulsants; Crotonates; Embryo, Mammalian; gamma-Aminobutyric Acid; Ganglia, Spinal; Glycine; Humans; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pentobarbital; Potassium Channels; Pregnanediones; Receptors, GABA-A; Taurine | 1999 |
Three GABA receptor-mediated postsynaptic potentials in interneurons in the rat lateral geniculate nucleus.
Topics: Animals; Baclofen; Bicuculline; Crotonates; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Geniculate Bodies; In Vitro Techniques; Interneurons; Models, Neurological; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Virulence Factors, Bordetella | 1999 |
Comparative potencies of CGP 47654A and CGP 46165A as GABA(B) receptor antagonists in rat brain.
Topics: Animals; Baclofen; Brain; Dose-Response Relationship, Drug; GABA Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neocortex; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Tritium | 1999 |
GABA-mediated representation of temporal information in rat barrel cortex.
Topics: Animals; Baclofen; Bicuculline; Brain Chemistry; Evoked Potentials, Somatosensory; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Rats; Rats, Long-Evans; Somatosensory Cortex; Time Perception; Vibrissae | 1999 |
Purkinje cell inhibitory responses to 3-APPA (3-aminopropylphosphinic acid) in RAT cerebellar slices.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cerebellum; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Purkinje Cells; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1999 |
Inhibition of transient LES relaxations and reflux in ferrets by GABA receptor agonists.
Topics: Animals; Baclofen; Behavior, Animal; Deglutition; Esophagogastric Junction; Female; Ferrets; GABA Agonists; gamma-Aminobutyric Acid; Gastroesophageal Reflux; Hydrogen-Ion Concentration; Manometry; Muscle Relaxation; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Pressure; Time Factors | 1999 |
GABAergic activation inhibits the hypothalamic-pituitary-ovaric axis and sexual development in the immature female rat. Associated changes in hypothalamic glutamatergic and taurinergic systems.
Topics: Aminooxyacetic Acid; Animals; Baclofen; Enzyme Inhibitors; Estradiol; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Hypothalamo-Hypophyseal System; Luteinizing Hormone; Muscimol; Organ Size; Ovary; Rats; Rats, Wistar; Sexual Maturation; Taurine | 1999 |
Facilitatory effect of unilateral lesion of the ventral tegmental area on locomotor response to stimulation of the contralateral ventral tegmental area: involvement of GABAergic transmission.
Topics: Animals; Baclofen; Bicuculline; Brain Mapping; Electric Stimulation; Functional Laterality; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Models, Neurological; Motor Activity; Muscimol; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Ventral Tegmental Area | 1999 |
mGluR7-like receptor and GABA(B) receptor activation enhance neurotoxic effects of N-methyl-D-aspartate in cultured mouse striatal GABAergic neurones.
Topics: Animals; Baclofen; Cell Survival; Cells, Cultured; Cerebellum; Corpus Striatum; Dizocilpine Maleate; Drug Synergism; Embryo, Mammalian; Excitatory Amino Acid Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Mice; N-Methylaspartate; Neurons; Neurotoxins; Propionates; Receptors, GABA-B; Receptors, Metabotropic Glutamate | 1999 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Picrotoxin; Substance Withdrawal Syndrome | 1999 |
A powerful GABA(B) receptor-mediated inhibition of GABAergic neurons in arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Female; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; In Situ Hybridization; In Vitro Techniques; Neural Inhibition; Neurons; Organophosphorus Compounds; Receptors, GABA-B | 1999 |
The modulation of calcium current by GABA metabotropic receptors in a sub-population of pallidal neurons.
Topics: Animals; Baclofen; Bicuculline; Calcium; Calcium Channel Blockers; Calcium Channels, N-Type; Calcium Channels, P-Type; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Male; Neurons; omega-Agatoxin IVA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 1999 |
Calcium sensing properties of the GABA(B) receptor.
Topics: Amino Acid Sequence; Animals; Baclofen; Calcium; Cerebral Cortex; CHO Cells; Cricetinae; GABA Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Male; Rats; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Xenopus | 1999 |
Selective block of rat and human neocortex GABA(B) receptors regulating somatostatin release by a GABA(B) antagonist endowed with cognition enhancing activity.
Topics: Adult; Animals; Baclofen; Female; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Male; Middle Aged; Neocortex; Nootropic Agents; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Somatostatin; Synaptosomes | 1999 |
Effects of inhibitory neurotransmitters on the mudpuppy (Necturus maculatus) locomotor pattern in vitro.
Topics: Animals; Baclofen; Bicuculline; Electromyography; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Locomotion; Membrane Potentials; N-Methylaspartate; Necturus; Neural Inhibition; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 1999 |
Excitatory and inhibitory synaptic inputs shape the discharge pattern of pump neurons of the nucleus tractus solitarii in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neural Inhibition; Neurons; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Strychnine; Synapses | 1999 |
Entrapping of impermeant probes of different size into nonpermeabilized synaptosomes as a method to study presynaptic mechanisms.
Topics: Animals; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Histological Techniques; Male; Molecular Probes; Neurology; Pertussis Toxin; Potassium; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptosomes; Tetanus Toxin; Virulence Factors, Bordetella | 2000 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
Autoradiographic distribution of radioactivity from (14)C-GABA in the mouse.
Topics: Animals; Autoradiography; Baclofen; Carbon Radioisotopes; Cartilage; GABA Antagonists; gamma-Aminobutyric Acid; Kidney Cortex; Liver; Male; Mice; Mice, Inbred ICR; Pineal Gland; Pituitary Gland; Receptors, GABA; Tissue Distribution; Whole-Body Irradiation | 2000 |
Dual control of dorsal raphe serotonergic neurons by GABA(B) receptors. Electrophysiological and microdialysis studies.
Topics: Animals; Baclofen; Electrophysiology; Extracellular Space; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Microdialysis; Microelectrodes; Neurons; Patch-Clamp Techniques; Raphe Nuclei; Rats; Rats, Wistar; Receptors, GABA-B; Serotonin | 2000 |
GABA synchronizes clock cells within the suprachiasmatic circadian clock.
Topics: Action Potentials; Animals; Baclofen; Biological Clocks; Cells, Cultured; GABA Agonists; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Neurons; Receptors, GABA-A; Suprachiasmatic Nucleus | 2000 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
GABAergic presynaptic inhibition of rat neostriatal afferents is mediated by Q-type Ca(2+) channels.
Topics: Animals; Baclofen; Calcium Channel Blockers; Calcium Channels, Q-Type; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Neostriatum; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-B | 2000 |
Effect of baclofen on cocaine self-administration in rats reinforced under fixed-ratio 1 and progressive-ratio schedules.
Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Dopamine; gamma-Aminobutyric Acid; Male; Rats; Rats, Wistar; Reinforcement Schedule; Self Administration | 2000 |
Bilateral blockade of NMDA receptors in anterior thalamus by dizocilpine (MK-801) injures pyramidal neurons in rat retrosplenial cortex.
Topics: Animals; Anterior Thalamic Nuclei; Baclofen; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; HSP70 Heat-Shock Proteins; Muscimol; Nerve Degeneration; Neural Pathways; Phytohemagglutinins; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia | 2000 |
Gabapentin "add-on therapy" for idiopathic chronic hiccup (ICH).
Topics: Acetates; Aged; Amines; Baclofen; Chronic Disease; Cisapride; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Gastrointestinal Agents; Hiccup; Humans; Male; Middle Aged; Muscle Relaxants, Central; Omeprazole; Treatment Outcome | 2000 |
Effect of experimental diabetes on GABA-mediated inhibition of neurally induced contractions in rat isolated trachea.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Wistar; Taurine; Tetrodotoxin; Trachea; Vasodilator Agents | 2000 |
GABAB-RI receptors in serotonergic neurons: effects of baclofen on 5-HT output in rat brain.
Topics: Animals; Baclofen; Brain; Carrier Proteins; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Neurons; Raphe Nuclei; Rats; Rats, Wistar; Receptors, GABA-B; RNA, Messenger; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2000 |
Activation of metabotropic GABAB receptors inhibited glutamate responses in spiral ganglion neurons of mice.
Topics: Age Factors; Animals; Animals, Newborn; Auditory Pathways; Baclofen; Bicuculline; Cells, Cultured; Cochlea; Dose-Response Relationship, Drug; Embryo, Mammalian; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hair Cells, Auditory; Mice; Neurons; Polymerase Chain Reaction; Receptors, GABA-B; Spiral Ganglion | 2000 |
GABA(B)-ergic modulation of burst rate and intersegmental coordination in lamprey: experiments and simulations.
Topics: Action Potentials; Animals; Baclofen; Calcium Channels; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Lampreys; Models, Neurological; N-Methylaspartate; Nerve Net; Neural Pathways; Neurons; Potassium Channels; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Time Factors | 2000 |
Taurine activates GABA(A) but not GABA(B) receptors in rat hippocampal CA1 area.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Organ Culture Techniques; Picrotoxin; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synapses; Taurine; Tetrodotoxin | 2000 |
Ethanol modulation of gamma-aminobutyric acid (GABA)-mediated inhibition of cerebellar Purkinje neurons: relationship to GABAb receptor input.
Topics: Animals; Baclofen; Central Nervous System Depressants; Cerebellum; Ethanol; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2000 |
GABA mediates presynaptic inhibition at glycinergic synapses in a rat auditory brainstem nucleus.
Topics: Animals; Baclofen; Carrier Proteins; Cochlear Nucleus; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Immunohistochemistry; In Vitro Techniques; Membrane Proteins; Organophosphorus Compounds; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Strychnine | 2000 |
Somatostatin inhibits GABAergic transmission in the sensory thalamus via presynaptic receptors.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Cats; Cell Membrane; Epilepsy; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Hormones; Male; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Sleep; Somatostatin; Synaptic Transmission; Tetrodotoxin; Ventral Thalamic Nuclei | 2000 |
Local GABAergic modulation of acetylcholine release from the cortex of freely moving rats.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Cholinesterase Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Male; Microdialysis; Muscimol; Organophosphorus Compounds; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Increased mesolimbic GABA concentration blocks heroin self-administration in the rat.
Topics: 4-Aminobutyrate Transaminase; Animals; Baclofen; Behavior, Animal; Bicuculline; Enzyme Inhibitors; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Heroin; Injections, Intraventricular; Lateral Ventricles; Male; Microinjections; Narcotics; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Self Administration; Telencephalon; Ventral Tegmental Area; Vigabatrin | 2000 |
The weaver mutation reverses the function of dopamine and GABA in mouse dopaminergic neurons.
Topics: Animals; Baclofen; Dopamine; G Protein-Coupled Inwardly-Rectifying Potassium Channels; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Mesencephalon; Mice; Mice, Neurologic Mutants; Nerve Degeneration; Neurons; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Dopamine D2; Receptors, GABA-B | 2000 |
Tonic and synaptically evoked presynaptic inhibition of sensory input to the rat olfactory bulb via GABA(B) heteroreceptors.
Topics: Animals; Baclofen; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Neural Inhibition; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2000 |
Novel mechanism for presynaptic inhibition: GABA(A) receptors affect the release machinery.
Topics: Action Potentials; Animals; Astacoidea; Baclofen; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Fura-2; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Intracellular Fluid; Magnesium; Neural Inhibition; Neuromuscular Junction; Patch-Clamp Techniques; Picrotoxin; Presynaptic Terminals; Reaction Time; Receptors, GABA-A; Synaptic Transmission; Temperature | 2000 |
Biophysical properties and responses to neurotransmitters of petrosal and geniculate ganglion neurons innervating the tongue.
Topics: Acetylcholine; Action Potentials; Animals; Baclofen; Carotid Sinus; Cell Separation; Dose-Response Relationship, Drug; Female; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Sensory; Geniculate Ganglion; In Vitro Techniques; Muscimol; Neurons; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Reaction Time; Stilbamidines; Substance P; Tongue | 2000 |
Effects of GABA on pancreatic exocrine secretion of rats.
Topics: Amylases; Animals; Baclofen; Bicuculline; Cholecystokinin; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Gastrin-Releasing Peptide; Hormones; In Vitro Techniques; Pancreas; Rats; Receptors, GABA-A; Secretin; Somatostatin; Tetrodotoxin | 2000 |
GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex.
Topics: Animals; Baclofen; Bicuculline; Bromodeoxyuridine; Cell Movement; Cellular Senescence; Cerebral Cortex; Chemotaxis; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Mitosis; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Organ Culture Techniques; Picrotoxin; Pregnancy; Rats; Receptors, GABA-A | 2000 |
Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors.
Topics: Amino Acid Sequence; Baclofen; Binding Sites; Cells, Cultured; GABA Agonists; gamma-Aminobutyric Acid; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Subunits; Receptors, GABA-B; Structure-Activity Relationship | 2000 |
The effect of internal GTPgammaS on GABA-release in cultured hippocampal neurons.
Topics: Animals; Baclofen; Cells, Cultured; Drug Interactions; Electric Stimulation; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Long-Term Potentiation; Membrane Potentials; Neural Inhibition; Neurons; Rats | 2000 |
The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.
Topics: Animals; Baclofen; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Receptors, GABA; Receptors, GABA-B | 2000 |
GABA spillover from single inhibitory axons suppresses low-frequency excitatory transmission at the cerebellar glomerulus.
Topics: Animals; Axons; Baclofen; Cerebellum; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Nerve Fibers; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synaptic Transmission; Temperature; Tetrodotoxin | 2000 |
Mediation of the cardiovascular response to spinal gamma-aminobutyric acid(B) receptor stimulation by adenosine A(1) receptors in anesthetized rats.
Topics: Adenosine; Amino Acids, Neutral; Animals; Baclofen; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Heart Rate; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Purinergic P1; Spinal Cord; Sympathetic Nervous System; Theobromine; Theophylline | 2000 |
The role of GABA-ergic system in human mammary gland pathology and in growth of transplantable murine mammary cancer.
Topics: Adolescent; Adult; Animals; Baclofen; Biomarkers, Tumor; Breast Neoplasms; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Middle Aged; Neoplasm Staging; Neoplasm Transplantation; Receptors, Estrogen; Receptors, GABA-B; Receptors, Progesterone; Tumor Cells, Cultured | 2000 |
GABAergic modulation of neurons in the nucleus of the solitary tract with ascending projections to the subfornical organ in the rat.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Male; Neural Pathways; Neurons; Pressoreceptors; Rats; Rats, Wistar; Solitary Nucleus; Subfornical Organ | 2001 |
Different control of GH secretion by gamma-amino- and gamma-hydroxy-butyric acid in 4-year abstinent alcoholics.
Topics: Adult; Alcoholism; Baclofen; Biomarkers; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hydroxybutyrates; Male; Statistics, Nonparametric; Temperance; Valproic Acid | 2001 |
Comparative activities of the enantiomeric GABA(B) receptor agonists CGP 44532 and 44533 in central and peripheral tissues.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; Male; Neocortex; Organophosphonates; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2001 |
Cross-talk between excitatory and inhibitory amino acids in the regulation of growth hormone secretion in neonatal rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics | 2001 |
The effects of GABA(B) agonists and gabapentin on mechanical hyperalgesia in models of neuropathic and inflammatory pain in the rat.
Topics: Acetates; Amines; Analgesics; Animals; Baclofen; Cyclohexanecarboxylic Acids; Electric Stimulation; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; In Vitro Techniques; Inflammation; Neuralgia; Rats; Rats, Wistar; Spinal Nerve Roots | 2001 |
Induction of wakefulness and inhibition of active (REM) sleep by GABAergic processes in the nucleus pontis oralis.
Topics: Animals; Baclofen; Bicuculline; Cats; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Pons; Receptors, GABA-A; Reticular Formation; Sleep, REM; Wakefulness | 2001 |
CGP 36216 is a selective antagonist at GABA(B) presynaptic receptors in rat brain.
Topics: Animals; Autoreceptors; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Neocortex; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2001 |
Involvement of pallidothalamic circuitry in working memory.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics, Opioid; Animals; Baclofen; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Extracellular Space; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Maze Learning; Mediodorsal Thalamic Nucleus; Memory, Short-Term; Motor Activity; Neural Inhibition; Neural Pathways; Neurons; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-B; Receptors, Opioid, mu | 2001 |
Heterogeneous susceptibility of GABA(A) receptor-mediated IPSCs to depolarization-induced suppression of inhibition in rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Carbachol; Cholinergic Agents; Diuretics; Electric Stimulation; Excitatory Amino Acid Antagonists; Furosemide; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Kinetics; Male; Neural Inhibition; Norepinephrine; Organ Culture Techniques; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sympathomimetics | 2001 |
Pharmacological characterization of homobaclofen on wild type and mutant GABA(B)1b receptors coexpressed with the GABA(B)2 receptor.
Topics: Animals; Baclofen; Cell Line; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Inositol Phosphates; Mutation; Rats; Receptors, GABA-B; Recombinant Proteins; Species Specificity; Stereoisomerism; Structure-Activity Relationship | 2001 |
Pretreatment of rat brain synaptosomes with GABA increases subsequent GABA uptake via GABA(B) receptor activation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Baclofen; Brain; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synaptosomes; Up-Regulation | 2001 |
Inhibitory effect of GABA on firing activity of rostral ventrolateral medullary neurons of rat in vitro.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Medulla Oblongata; Neurons; Rats; Rats, Sprague-Dawley | 1998 |
Involvement of central GABAergic neurons in basal and diurnal changes of tuberoinfundibular dopaminergic neuronal activity and prolactin secretion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Circadian Rhythm; Dopamine; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Median Eminence; Muscimol; Neurons; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2001 |
GABA inhibition of immortalized gonadotropin-releasing hormone neuronal excitability involves GABA(A) receptors negatively coupled to cyclic adenosine monophosphate formation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Baclofen; Bicuculline; Calcium; Calcium Channels; Cell Line, Transformed; Cell Membrane; Colforsin; Cyclic AMP; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Kinetics; Muscimol; Neurons; Potassium; Receptors, GABA-A | 2001 |
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
Topics: Acetates; Amines; Analgesics; Animals; Anticonvulsants; Baclofen; Calcium Channels; Calcium Signaling; Cyclohexanecarboxylic Acids; GABA Agonists; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Male; Mice; Mice, Transgenic; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2001 |
Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice.
Topics: Action Potentials; Animals; Baclofen; Behavior, Animal; Central Nervous System; Down-Regulation; Epilepsy; GABA Agonists; gamma-Aminobutyric Acid; Gene Targeting; Heterozygote; Mice; Mice, Knockout; Neural Inhibition; Neurons; Phenotype; Radioligand Assay; Receptors, GABA-B; Reflex, Startle; RNA, Messenger; Seizures; Synapses; Synaptic Transmission | 2001 |
gamma-Aminobutyric acid receptor subtype antagonists differentially alter opioid-induced feeding in the shell region of the nucleus accumbens in rats.
Topics: Animals; Baclofen; Bicuculline; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Opioid | 2001 |
GABA enhances transmission at an excitatory glutamatergic synapse.
Topics: Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Glutamic Acid; In Vitro Techniques; Iontophoresis; Male; Membrane Potentials; Motor Neurons; Muscimol; Muscles; Nephropidae; Neuromuscular Junction; Patch-Clamp Techniques; Picrotoxin; Receptors, GABA-B; Synapses; Synaptic Transmission | 2001 |
Involvement of GABAergic systems in manifestation of pharmacological activity of desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Baclofen; Desipramine; Freund's Adjuvant; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Reaction Time | 2001 |
Inhibitory effect of 17beta-estradiol in the parabrachial nucleus is mediated by GABA.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Estradiol; Estrogen Antagonists; Female; Fulvestrant; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neural Pathways; Neurons; Ovariectomy; Pons; Rats; Receptors, Estrogen; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Vagus Nerve; Ventral Thalamic Nuclei; Visceral Afferents | 2001 |
Hemorrhage activates catecholaminergic neurons sensitive to GABA in the nucleus of the solitary tract with ascending projections to the subfornical organ in rats.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Blood Pressure; Catecholamines; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hemorrhage; Iontophoresis; Male; Neurons; Oxidopamine; Pressoreceptors; Rats; Rats, Wistar; Solitary Nucleus; Subfornical Organ; Sympatholytics | 2001 |
Regulation of muscarinic acetylcholine receptor-mediated synaptic responses by GABA(B) receptors in the rat hippocampus.
Topics: Animals; Atropine; Baclofen; Excitatory Postsynaptic Potentials; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Muscarinic Antagonists; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Muscarinic; Synapses; Synaptic Transmission | 2001 |
Evaluation of functional GABA(B) receptors in dental pulp.
Topics: Animals; Baclofen; Biotransformation; Cattle; Dental Pulp; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Radiopharmaceuticals; Receptors, GABA-B; Receptors, Opioid; Statistics, Nonparametric; Sulfur Radioisotopes | 2001 |
Baclofen attenuates harmaline induced tremors in rats.
Topics: Animals; Baclofen; Brain; Dose-Response Relationship, Drug; Drug Interactions; Electromyography; Essential Tremor; Female; GABA Agonists; gamma-Aminobutyric Acid; Harmaline; Muscle Contraction; Olivary Nucleus; Rats; Rats, Wistar; Reaction Time; Receptors, GABA-B; Synaptic Transmission; Tremor | 2001 |
GABA receptors modulate trigeminovascular nociceptive neurotransmission in the trigeminocervical complex.
Topics: Animals; Baclofen; Bicuculline; Cats; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Muscimol; Neurons; Nociceptors; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Time Factors; Trigeminal Nuclei | 2001 |
Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Male; Microdialysis; Microinjections; Muscimol; Neurons; Organophosphorus Compounds; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2001 |
The activation of gamma aminobutyric acid(A) receptors in the paraventricular nucleus of the hypothalamus reduces non-contact penile erections in male rats.
Topics: Animals; Baclofen; Copulation; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Inhibition; Neural Pathways; Neurons; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 2001 |
Random response fluctuations lead to spurious paired-pulse facilitation.
Topics: Animals; Baclofen; Computer Simulation; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Models, Neurological; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Reproducibility of Results | 2001 |
Tonic activity and GABA responsiveness of medial vestibular nucleus neurons in aged rats.
Topics: Aging; Animals; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Muscimol; Neuronal Plasticity; Neurons; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vestibular Nuclei | 2001 |
GABA(A) and GABA(B) receptors in the anterior piriform cortex modulate feeding in rats.
Topics: Amino Acids; Animals; Baclofen; Bicuculline; Feeding Behavior; Food Deprivation; Food, Formulated; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Neural Inhibition; Neurons; Olfactory Pathways; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; RNA, Messenger; Threonine | 2002 |
Opiate-induced motor stimulation is regulated by gamma-aminobutyric acid type B receptors found in the ventral tegmental area in mice.
Topics: Animals; Baclofen; Dopamine; Drug Interactions; Feedback; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Narcotics; Neural Inhibition; Neural Pathways; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Receptors, GABA-B; Synaptic Transmission; Ventral Tegmental Area | 2002 |
Opposite roles of GABA and excitatory amino acids on the control of GAD expression in cultured retina cells.
Topics: Animals; Baclofen; Cells, Cultured; Chick Embryo; Cytarabine; Excitatory Amino Acid Agonists; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Immunohistochemistry; Isoxazoles; Kainic Acid; Nitric Oxide; Retina | 2002 |
[Specific binding of GABA in the adrenal glands and catecholamine blood and adrenal gland levels in rats under stress with inhibited functioning of the hypothalamus-hypophyseal-adrenocortical systems].
Topics: Adrenal Glands; Animals; Baclofen; Catecholamines; Dopamine; Epinephrine; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Male; Norepinephrine; Pituitary-Adrenal System; Rats; Rats, Wistar; Stress, Physiological; Swimming | 2001 |
Presynaptic short-term depression is maintained during regulation of transmitter release at a GABAergic synapse in rat hippocampus.
Topics: Animals; Baclofen; Cadmium; Calcium Channels; Cholinergic Agonists; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Neurotransmitter Agents; Presynaptic Terminals; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Time Factors | 2002 |
Baclofen inhibits ANP-mediated cyclic GMP synthesis in the rat cervical spinal cord.
Topics: Aging; Animals; Atrial Natriuretic Factor; Baclofen; Cervical Vertebrae; Cyclic GMP; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Immunohistochemistry; Male; Muscle Spasticity; Nerve Net; Nitric Oxide Donors; Nociceptors; Pain; Posterior Horn Cells; Rats; Rats, Inbred Lew; Receptors, GABA-B | 2002 |
Reduction of drug-induced yawning and penile erection and of noncontact erections in male rats by the activation of GABAA receptors in the paraventricular nucleus: involvement of nitric oxide.
Topics: Animals; Apomorphine; Baclofen; Bicuculline; Copulation; Extracellular Space; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; N-Methylaspartate; Neural Inhibition; Nitrates; Nitric Oxide; Nitrites; Oxytocin; Paraventricular Hypothalamic Nucleus; Penile Erection; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Yawning | 2002 |
Mechanism underlying gamma-aminobutyric acid-induced antihypertensive effect in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baclofen; Blood Pressure; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscimol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Systole; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2002 |
GABA interacts with photic signaling in the suprachiasmatic nucleus to regulate circadian phase shifts.
Topics: Animals; Baclofen; Circadian Rhythm; Cricetinae; Excitatory Amino Acid Agonists; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesocricetus; Muscimol; N-Methylaspartate; Neural Inhibition; Neurons; Photic Stimulation; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Suprachiasmatic Nucleus; Synaptic Transmission; Tetrodotoxin | 2002 |
Interactions between GABAergic and aminoacidergic pathways in the control of gonadotropin and GH secretion in pre-pubertal female rats.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Bicuculline; Excitatory Amino Acids; Female; Follicle Stimulating Hormone; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Human Growth Hormone; Kainic Acid; Luteinizing Hormone; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Sexual Maturation | 2002 |
Comparison of receptive field expansion produced by GABA(B) and GABA(A) receptor antagonists in raccoon primary somatosensory cortex.
Topics: Afferent Pathways; Animals; Baclofen; Female; Fingers; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mechanoreceptors; Neural Inhibition; Neuronal Plasticity; Neurons; Phosphinic Acids; Propanolamines; Raccoons; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Skin; Somatosensory Cortex; Synaptic Transmission; Touch | 2002 |
Treatment of spasticity.
Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Spasticity; Paralysis; Rhizotomy | 2002 |
Functional GABA(B) receptors expressed in cultured calvarial osteoblasts.
Topics: 3T3 Cells; Alkaline Phosphatase; Alternative Splicing; Animals; Baclofen; Calcium; Cells, Cultured; Cyclic AMP; DNA, Complementary; GABA Agonists; gamma-Aminobutyric Acid; Immunoblotting; Mice; Osteoblasts; Protein Structure, Tertiary; Rats; Rats, Wistar; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; Skull; Time Factors | 2002 |
Analysis of the function of GABA(B) receptors on inhibitory afferent neurons of Purkinje cells in the cerebellar cortex of the rat.
Topics: Animals; Autoreceptors; Baclofen; Cerebellar Cortex; GABA Agonists; gamma-Aminobutyric Acid; Neural Inhibition; Neurons, Afferent; Presynaptic Terminals; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-B; Synapses; Synaptic Transmission | 2002 |
GABAergic modulation of primary gustatory afferent synaptic efficacy.
Topics: Animals; Baclofen; Bicuculline; Carrier Proteins; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Goldfish; Membrane Proteins; Membrane Transport Proteins; Muscimol; Neurons, Afferent; Organic Anion Transporters; Phosphinic Acids; Propanolamines; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Synapses; Taste | 2002 |
Inhibitory effects of GABA(B) receptor agonists on swallowing in the dog.
Topics: Animals; Baclofen; Deglutition; Dogs; Esophagogastric Junction; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Muscle Relaxation; Organophosphonates; Phosphinic Acids; Receptors, GABA-B | 2002 |
GABAergic control of food intake in the meat-type chickens.
Topics: Animals; Baclofen; Bicuculline; Chickens; Dose-Response Relationship, Drug; Eating; GABA Agents; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Meat; Muscimol | 2002 |
GABA and development of the Xenopus optic projection.
Topics: Analysis of Variance; Animals; Baclofen; Blotting, Western; Culture Techniques; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Embryonic Development; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; Muscimol; Neurites; Neurons; Organophosphorus Compounds; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Retinal Ganglion Cells; Visual Pathways; Xenopus laevis | 2002 |
An autocrine role for pituitary GABA: activation of GABA-B receptors and regulation of growth hormone levels.
Topics: Animals; Autocrine Communication; Baclofen; Female; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Growth Hormone; Male; Pituitary Gland; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Tumor Cells, Cultured | 2002 |
GABAergic systems in the nucleus tractus solitarius regulate noradrenaline release in the subfornical organ area in the rat.
Topics: Analysis of Variance; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microdialysis; Muscimol; Norepinephrine; Rats; Rats, Wistar; Solitary Nucleus; Subfornical Organ | 2002 |
GABA-mediated neurotransmission in the ventrolateral NTS plays a role in respiratory regulation in the rat.
Topics: Animals; Apnea; Baclofen; Bicuculline; Cardiovascular System; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Kynurenic Acid; Male; Microinjections; Muscimol; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA; Respiration; Synaptic Transmission; Ventral Thalamic Nuclei | 2002 |
Interaction of pentobarbital with gabaergic drugs acting on the Cl(-)-ATPase activity of the plasma membranes from bream brain (Abramis brama L.).
Topics: Adenosine Triphosphatases; Animals; Anion Transport Proteins; Baclofen; Bicuculline; Brain; Cell Membrane; Chlorides; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Pentobarbital; Picrotoxin; Receptors, GABA-A; Sea Bream | 2002 |
Improvement of acquired pendular nystagmus by gabapentin: case report.
Topics: Acetates; Administration, Oral; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Middle Aged; Multiple Sclerosis; Nystagmus, Pathologic; Treatment Outcome | 2001 |
Functional GABAB receptors are present in guinea pig nodose ganglion cell bodies but not in peripheral mechanosensitive endings.
Topics: Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Mechanoreceptors; Nerve Endings; Nerve Fibers, Unmyelinated; Nodose Ganglion; Peripheral Nerves; Receptors, GABA-B | 2002 |
Plasticity of gamma-aminobutyrate receptors in the medial vestibular nucleus of rat after inferior cerebellar peduncle transection.
Topics: Animals; Baclofen; Behavior, Animal; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Mesencephalon; Muscimol; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, GABA; Vestibular Nuclei | 2002 |
The ATP-mediated fast current of rat dorsal root ganglion neurons is a novel effector for GABA(B) receptor activation.
Topics: Adenosine Triphosphate; Animals; Baclofen; Benzylamines; Cells, Cultured; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Phosphinic Acids; Picrotoxin; Rats; Receptors, GABA-A; Receptors, GABA-B; Receptors, Purinergic P2; Receptors, Purinergic P2X3 | 2003 |
Gamma-aminobutyric acid neuropharmacological investigations on narcosis produced by nitrogen, argon, or nitrous oxide.
Topics: Anesthesia, Inhalation; Animals; Argon; Baclofen; Flumazenil; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Motor Activity; Nitrogen; Nitrous Oxide; Pyridazines; Rats; Rats, Sprague-Dawley | 2003 |
GABAB receptor-mediated presynaptic potentiation of ATP ionotropic receptors in rat midbrain synaptosomes.
Topics: Adenosine Triphosphate; Animals; Baclofen; Calcium; Colforsin; Competitive Bidding; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Muscimol; Nerve Tissue Proteins; Picrotoxin; Rats; Receptors, GABA-B; Receptors, Purinergic P2; Receptors, Purinergic P2X; Synaptosomes; Time Factors | 2003 |
GABAergic modulation of hippocampal glutamatergic neurons: an in vivo microdialysis study.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Microdialysis; Muscimol; Neurons; Potassium Chloride; Rats; Receptors, GABA; Synaptosomes; Taurine; Time Factors; Veratridine | 2003 |
Baclofen attenuates conditioned locomotion to cues associated with cocaine administration and stabilizes extracellular glutamate levels in rat nucleus accumbens.
Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Motor Activity; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reward; Substance Withdrawal Syndrome; Synaptic Transmission | 2003 |
Glutamate and GABA modulate dopamine in the pedunculopontine tegmental nucleus.
Topics: Amphetamine; Animals; Baclofen; Behavior, Animal; Dopamine; Dopamine Uptake Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Locomotion; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Tegmentum Mesencephali | 2003 |
Involvement of glutamate and gamma-amino-butyric acid receptor systems on gastric acid secretion induced by activation of kappa-opioid receptors in the central nervous system in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Benzeneacetamides; Benzomorphans; Bicuculline; Brain; Dynorphins; gamma-Aminobutyric Acid; Gastric Acid; Injections, Intraventricular; Ketanserin; Male; Perfusion; Piperazines; Pyrrolidines; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Receptors, Serotonin; Stomach | 2003 |
Levetiracetam has no significant gamma-aminobutyric acid-related effect on paired-pulse interaction in the dentate gyrus of rats.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Clonazepam; Convulsants; Dentate Gyrus; Diazepam; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Rats, Sprague-Dawley; Receptors, GABA; Synaptic Transmission; Time Factors | 2003 |
Properties and modulation of the G protein-coupled K+ channel in rat cerebellar granule neurons: ATP versus phosphatidylinositol 4,5-bisphosphate.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Animals, Newborn; Arachidonic Acids; Baclofen; Carrier Proteins; Cerebellum; Cytosol; Electrophysiology; Endocannabinoids; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; gamma-Aminobutyric Acid; Neoplasm Proteins; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Polyunsaturated Alkamides; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Signal Transduction | 2003 |
GABAB receptor transduction mechanisms, and cross-talk between protein kinases A and C, in GABAergic terminals synapsing onto neurons of the rat nucleus basalis of Meynert.
Topics: Adenine; Animals; Baclofen; Basal Nucleus of Meynert; Calcium Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Conductivity; Enzyme Inhibitors; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Neural Inhibition; Neurons; Potassium Channels; Presynaptic Terminals; Protein Kinase C; Rats; Rats, Wistar; Receptors, GABA-B; Signal Transduction; Synapses | 2003 |
Positive regulation of GABA(B) receptors dually coupled to cyclic AMP by the allosteric agent CGP7930.
Topics: Adenylyl Cyclases; Allosteric Regulation; Animals; Baclofen; Calmodulin; Colforsin; Corpus Striatum; Corticotropin-Releasing Hormone; Cyclic AMP; Cytoplasmic Granules; Drug Synergism; Frontal Lobe; gamma-Aminobutyric Acid; Gene Expression; Male; Olfactory Bulb; Phenols; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-B; Signal Transduction | 2003 |
Different actions of gabapentin and baclofen in hippocampus from weaver mice.
Topics: Acetates; Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Down-Regulation; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Hippocampus; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Neural Inhibition; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Receptors, GABA-B; Species Specificity; Synaptic Transmission | 2003 |
Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex.
Topics: Animals; Baclofen; Bupivacaine; Cerebral Cortex; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Models, Neurological; Neurons; Pain Threshold; Phentolamine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vigabatrin | 2003 |
Spontaneous synaptic activity is primarily GABAergic in vestibular nucleus neurons of the chick embryo.
Topics: Animals; Baclofen; Chick Embryo; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Glycine; Neural Inhibition; Neurons; Patch-Clamp Techniques; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Vestibular Nuclei | 2003 |
Gabapentin actions on Kir3 currents and N-type Ca2+ channels via GABAB receptors in hippocampal pyramidal cells.
Topics: Acetates; Action Potentials; Amines; Animals; Anticonvulsants; Baclofen; Barium; Calcium Channel Blockers; Calcium Channels, N-Type; Cell Membrane; Cesium; Cyclohexanecarboxylic Acids; Epilepsy; Ethylmaleimide; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gabapentin; gamma-Aminobutyric Acid; GTP-Binding Proteins; Hippocampus; Male; omega-Conotoxin GVIA; Organ Culture Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2003 |
GABA mediates autoreceptor feedback inhibition in the rat carotid body via presynaptic GABAB receptors and TASK-1.
Topics: Animals; Autoreceptors; Baclofen; Calcium Channels; Carotid Body; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Electrophysiology; Feedback, Physiological; Fluorescent Antibody Technique; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Nerve Tissue Proteins; Patch-Clamp Techniques; Potassium; Potassium Channels; Potassium Channels, Tandem Pore Domain; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-B; Receptors, Presynaptic; Reverse Transcriptase Polymerase Chain Reaction; Synapses | 2003 |
N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.
Topics: Allosteric Regulation; Animals; Baclofen; CHO Cells; Cricetinae; Cyclopentanes; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Humans; Kinetics; Oocytes; Potassium Channels; Pyrimidines; Radioligand Assay; Signal Transduction; Structure-Activity Relationship; Sulfur Radioisotopes; Xenopus | 2003 |
Synaptic strength between motoneurons and terminals of the dorsolateral funiculus is regulated by GABA receptors in the turtle spinal cord.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Electrophysiology; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Motor Neurons; Muscimol; Picrotoxin; Receptors, GABA; Spinal Cord; Synapses; Synaptic Transmission; Time Factors; Turtles | 2004 |
Attenuation of cerebellar tremor with implantation of an intrathecal baclofen pump: the role of gamma-aminobutyric acidergic pathways. Case report.
Topics: Baclofen; Cerebellum; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Middle Aged; Multiple Sclerosis; Receptors, GABA; Tremor | 2003 |
Modulation of noradrenaline release in the median preoptic area by GABAergic inputs from the organum vasculosum of the lamina terminalis in the rat.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; Male; Microdialysis; Norepinephrine; Preoptic Area; Rats; Rats, Wistar | 2004 |
The GABAB receptor agonists baclofen and CGP44532 decreased nicotine self-administration in the rat.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; gamma-Aminobutyric Acid; Male; Nicotine; Organophosphonates; Phosphinic Acids; Rats; Rats, Wistar; Self Administration | 2004 |
Hypertension alters GABA receptor-mediated inhibition of neurons in the nucleus of the solitary tract.
Topics: Action Potentials; Animals; Baclofen; Baroreflex; Blood Pressure; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Hypertension, Renal; Male; Muscimol; Neural Inhibition; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus | 2003 |
Regulation of exocytosis from single visualized GABAergic boutons in hippocampal slices.
Topics: Animals; Baclofen; Calcium Channels; Cyclohexanols; Electric Stimulation; Excitatory Postsynaptic Potentials; Exocytosis; Fluorescent Dyes; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Isoenzymes; Luminescent Proteins; Mice; Mice, Transgenic; Neural Inhibition; Patch-Clamp Techniques; Presynaptic Terminals; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Recombinant Fusion Proteins | 2003 |
Swimming behavior regulation by GABAB receptors in Paramecium.
Topics: Animals; Baclofen; Calcium; Calcium Channels; Cilia; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Membrane Potentials; Motor Activity; Paramecium; Receptors, GABA-B; Swimming | 2003 |
Lamina-specific differences in GABA(B) autoreceptor-mediated regulation of spontaneous GABA release in rat entorhinal cortex.
Topics: Action Potentials; Animals; Autoreceptors; Baclofen; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Entorhinal Cortex; Evoked Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neural Inhibition; Phosphinic Acids; Propanolamines; Rats; Receptors, GABA-B | 2004 |
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.
Topics: 4-Butyrolactone; Adjuvants, Anesthesia; Animals; Anticonvulsants; Autoradiography; Baclofen; Behavior, Animal; Benzocycloheptenes; Binding, Competitive; Body Weight; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroencephalography; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Organophosphorus Compounds; Phenols; Radioligand Assay; Receptors, GABA-B; Sodium Oxybate; Time Factors | 2003 |
Plasticity of GABA(B) receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus.
Topics: Animals; Baclofen; Cells, Cultured; Excitatory Postsynaptic Potentials; GABA Agonists; gamma-Aminobutyric Acid; Male; Mossy Fibers, Hippocampal; Neural Inhibition; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Status Epilepticus; Synapses; Synaptic Transmission | 2003 |
Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism.
Topics: Aged; Aged, 80 and over; Baclofen; Dipeptides; Enzyme Induction; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Immunohistochemistry; Isoenzymes; Lymphatic Metastasis; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Middle Aged; Neoplasm Metastasis; Prostatic Hyperplasia; Prostatic Neoplasms; Protease Inhibitors; Receptors, GABA-B; Risk Factors | 2003 |
GABA modulates presynaptic signalling mediated by dinucleotides on rat synaptic terminals.
Topics: Animals; Baclofen; Calcium; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Dinucleoside Phosphates; GABA Agonists; gamma-Aminobutyric Acid; Mesencephalon; Nerve Endings; Presynaptic Terminals; Rats; Receptors, GABA-B | 2004 |
An Intrinsic gamma-aminobutyric acid (GABA)ergic system in the adrenal cortex: findings from human and rat adrenal glands and the NCI-H295R cell line.
Topics: Adrenal Cortex; Alternative Splicing; Animals; Baclofen; Calcium Channels, T-Type; Carrier Proteins; Cell Line; Electric Conductivity; GABA Agonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression; Glutamate Decarboxylase; Glutamic Acid; Humans; Immunohistochemistry; Isoenzymes; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters; Patch-Clamp Techniques; Rats; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Gamma-hydroxybutyric acid, unlike gamma-aminobutyric acid, does not stimulate Gi/Go proteins in rat brain membranes.
Topics: Animals; Baclofen; Brain; Cell Membrane; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydroxybutyrates; Male; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface | 2004 |
Relationship between the antinociceptive response to desipramine and changes in GABAB receptor function and subunit expression in the dorsal horn of the rat spinal cord.
Topics: Analgesics; Animals; Antidepressive Agents, Tricyclic; Baclofen; Desipramine; gamma-Aminobutyric Acid; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Male; Posterior Horn Cells; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spinal Cord | 2004 |
Suppression of GABA(B) receptor function in vivo by disulfide reducing agent, DL-dithiothreitol (DTT).
Topics: Animals; Baclofen; Conditioning, Operant; Discrimination Learning; Dithiothreitol; Drug Interactions; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Mice; Mice, Inbred DBA; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Long-Evans; Reflex | 2004 |
Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue.
Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Allylglycine; Amination; Animals; Aspartic Acid; Baclofen; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Ketoglutaric Acids; Leucine; Male; Oxidation-Reduction; Perfusion; Potassium Chloride; Rats; Rats, Wistar; Receptors, GABA | 2004 |
Differential expression of gamma-aminobutyric acid type B receptor subunit mRNAs in the developing nervous system and receptor coupling to adenylyl cyclase in embryonic neurons.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Baclofen; Binding Sites; Blotting, Western; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Developmental; In Situ Hybridization; Inhibitory Concentration 50; Male; Nervous System; Neurons; Organophosphorus Compounds; Phosphodiesterase Inhibitors; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Tritium | 2004 |
Chiral capillary electrophoretic resolution of baclofen, gabaergic ligand, using highly sulfated cyclodextrins.
Topics: Baclofen; Buffers; Cyclodextrins; Electrophoresis, Capillary; GABA Agonists; gamma-Aminobutyric Acid; Ligands; Sensitivity and Specificity; Sulfuric Acids | 2004 |
GABA-mediated attenuation of noradrenaline release in the rat median preoptic area caused by intravenous injection of metaraminol.
Topics: Adrenergic alpha-Agonists; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intravenous; Male; Metaraminol; Microdialysis; Norepinephrine; Preoptic Area; Rats; Rats, Wistar; Receptors, GABA | 2004 |
GABAergic synapses of the suprachiasmatic nucleus exhibit a diurnal rhythm of short-term synaptic plasticity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Baclofen; Calcium; Circadian Rhythm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Models, Neurological; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus; Synapses; Time Factors | 2004 |
Peripheral GABAB agonists stimulate gastric acid secretion in mice.
Topics: Animals; Antibodies, Monoclonal; Atropine; Baclofen; Deoxyglucose; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gastric Acid; Gastrins; Imidazoles; Injections, Intravenous; Male; Mice; Mice, Knockout; Muscimol; Organophosphorus Compounds; Pentagastrin; Peptides, Cyclic; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Somatostatin; Somatostatin; Time Factors; Vagotomy | 2004 |
GABA mediaties the inhibitory effect of lateral amygdaloid nucleus stimulation on the acoustic response of neurons in A I cortex: An in vivo microiontophoretic study.
Topics: Acoustic Stimulation; Amygdala; Animals; Baclofen; Bicuculline; Cerebral Cortex; Electric Stimulation; Evoked Potentials, Auditory; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Male; Microelectrodes; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2004 |
Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain.
Topics: Animals; Baclofen; Bicuculline; Calcitonin Gene-Related Peptide; gamma-Aminobutyric Acid; Ganglia, Spinal; Genetic Therapy; Genetic Vectors; Glutamate Decarboxylase; Hyperalgesia; Injections, Subcutaneous; Isoenzymes; Neurons; Pain; Rats; Simplexvirus; Spinal Cord Injuries; Tissue Distribution; Transduction, Genetic | 2004 |
Gabapentin activates presynaptic GABAB heteroreceptors in rat cortical slices.
Topics: Amines; Animals; Baclofen; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Morpholines; Neocortex; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Presynaptic; Tritium | 2004 |
Mechanism of GABA receptor-mediated inhibition of spontaneous GABA release onto cerebellar Purkinje cells.
Topics: Action Potentials; Age Factors; Animals; Baclofen; Barium; Cadmium; Calcium; Cerebellum; Colforsin; Drug Interactions; Enzyme Inhibitors; Exotoxins; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; Neural Inhibition; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Purkinje Cells; Receptors, GABA-A; Ruthenium Red; Synaptic Transmission; Tetrodotoxin | 2004 |
Effects of repeated cocaine on medial prefrontal cortical GABAB receptor modulation of neurotransmission in the mesocorticolimbic dopamine system.
Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Synergism; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Microdialysis; Nucleus Accumbens; Prefrontal Cortex; Rats; Receptors, GABA-B; Synaptic Transmission; Ventral Tegmental Area | 2004 |
Cocaine alters GABA(B)-mediated G-protein activation in the ventral tegmental area of female rats: modulation by estrogen.
Topics: Animals; Autoradiography; Baclofen; Cocaine; Dopamine Uptake Inhibitors; Entorhinal Cortex; Enzyme Activation; Estrogens; Female; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Ovariectomy; Rats; Receptors, GABA-B; Ventral Tegmental Area | 2004 |
Involvement of 5-HT1B receptors within the ventral tegmental area in regulation of mesolimbic dopaminergic neuronal activity via GABA mechanisms: a study with dual-probe microdialysis.
Topics: Animals; Baclofen; Benzamides; Biphenyl Compounds; Dopamine; GABA Agonists; gamma-Aminobutyric Acid; Male; Microdialysis; Neural Pathways; Neurons; Nucleus Accumbens; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Serotonin Antagonists; Serotonin Receptor Agonists; Ventral Tegmental Area | 2004 |
Local protein synthesis and GABAB receptors regulate the reversibility of long-term potentiation at murine hippocampal mossy fibre-CA3 synapses.
Topics: Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Morpholines; Mossy Fibers, Hippocampal; Neuronal Plasticity; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, GABA-B | 2004 |
Development of GABAB subunits and functional GABAB receptors in rat cultured hippocampal neurons.
Topics: Animals; Baclofen; Cells, Cultured; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Hippocampus; Neurons; Protein Subunits; Rats; Receptors, GABA-B | 2004 |
Activation mechanism of the heterodimeric GABA(B) receptor.
Topics: Allosteric Regulation; Animals; Baclofen; Dimerization; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Humans; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Receptors, G-Protein-Coupled; Receptors, GABA-B | 2004 |
Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats.
Topics: Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Food, Formulated; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Neural Inhibition; Nipecotic Acids; Nitroprusside; Organophosphorus Compounds; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Sodium Chloride, Dietary; Solitary Nucleus | 2004 |
Spastic paretic hemifacial contracture (SPHC) in a patient with multiple sclerosis. A clinical, EMG and neuroimaging study.
Topics: Adult; Amines; Baclofen; Blinking; Brain; Clonazepam; Cyclohexanecarboxylic Acids; Electromyography; Evoked Potentials; Excitatory Amino Acid Antagonists; Facial Muscles; Female; GABA Agonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hemifacial Spasm; Humans; Magnetic Resonance Imaging; Multiple Sclerosis; Neurons; Pons | 2004 |
Rapid dopaminergic signaling by interneurons that contain markers for catecholamines and GABA in the feeding circuitry of Aplysia.
Topics: Animals; Aplysia; Baclofen; Catecholamines; Dopamine; Feeding Behavior; gamma-Aminobutyric Acid; Interneurons; Nerve Net; Signal Transduction; Sulpiride; Synaptic Transmission | 2005 |
Dual effect of GABA on descending monosynaptic excitatory postsynaptic potential in frog lumbar motoneurons.
Topics: Animals; Baclofen; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lumbosacral Region; Motor Neurons; Rana ridibunda; Spinal Cord; Synapses; Synaptic Transmission | 2004 |
Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat.
Topics: Alkanesulfonates; Amines; Amitriptyline; Animals; Baclofen; Behavior, Animal; Benzoxazines; Carbamazepine; Cyclohexanecarboxylic Acids; Cyclohexanols; Discrimination Learning; Dose-Response Relationship, Drug; Dronabinol; Gabapentin; gamma-Aminobutyric Acid; Indans; Male; Molecular Structure; Morphine; Morpholines; Naphthalenes; Nitriles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sulfonic Acids | 2004 |
Effects of microinjections of neurotoxin AvTx8, isolated from the social wasp Agelaia vicina (Hymenoptera, Vespidae) venom, on GABAergic nigrotectal pathways.
Topics: Animals; Baclofen; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Neural Pathways; Neurotoxins; Rats; Rats, Wistar; Stimulation, Chemical; Substantia Nigra; Superior Colliculi; Wasp Venoms; Wasps | 2005 |
Injections of baclofen into the ventral medial prefrontal cortex block the initiation, but not the expression, of cocaine sensitization in rats.
Topics: Animals; Baclofen; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Motor Activity; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2005 |
Effects of GABAergic transmissions on the immunoreactivities of calcium binding proteins in the gerbil hippocampus.
Topics: Animals; Baclofen; Bicuculline; Calbindin 2; Calbindins; Calcium-Binding Proteins; Cell Count; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Gerbillinae; Hippocampus; Immunohistochemistry; Muscimol; Neurons; Parvalbumins; S100 Calcium Binding Protein G; Seizures; Synaptic Transmission | 2005 |
Functional GABA(B) receptors are expressed at the cone photoreceptor terminals in bullfrog retina.
Topics: Animals; Baclofen; Barium; Calcium Signaling; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Rana catesbeiana; Receptors, GABA-B; Retina; Retinal Cone Photoreceptor Cells; Synaptic Transmission; Vision, Ocular | 2005 |
GABAergic modulation of the activity of globus pallidus neurons in primates: in vivo analysis of the functions of GABA receptors and GABA transporters.
Topics: Action Potentials; Animals; Anisoles; Baclofen; Brain Mapping; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Macaca mulatta; Membrane Transport Modulators; Membrane Transport Proteins; Microdialysis; Microscopy, Immunoelectron; Muscimol; Neurons; Nipecotic Acids; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA | 2005 |
Gamma aminobutyric acid regulates glucosensitive neuropeptide Y neurons in arcuate nucleus via A/B receptors.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Bicuculline; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glucose; Immunohistochemistry; Male; Microscopy, Immunoelectron; Muscimol; Neurons; Neuropeptide Y; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA; Time Factors | 2005 |
Voltage-gated Ca2+ channel subtypes mediating GABAergic transmission in the rat supraoptic nucleus.
Topics: Adenosine; Animals; Baclofen; Calcium Channels, L-Type; Calcium Channels, Q-Type; Evoked Potentials; Female; GABA Agonists; gamma-Aminobutyric Acid; Membrane Potentials; Neural Inhibition; Organ Culture Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Supraoptic Nucleus; Synaptic Transmission | 2005 |
GABAergic control of the ascending input from the median raphe nucleus to the limbic system.
Topics: Afferent Pathways; Animals; Baclofen; Brain Mapping; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electroencephalography; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Limbic System; Male; Microdialysis; Muscimol; Neural Networks, Computer; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reaction Time; Spectrum Analysis; Time Factors | 2005 |
Distinct mechanisms of presynaptic inhibition at GABAergic synapses of the rat substantia nigra pars compacta.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aminobutyrates; Animals; Animals, Newborn; Baclofen; Cadmium Chloride; Dopamine; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Ionomycin; Ionophores; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Presynaptic Terminals; Propanolamines; Rats; Sodium Channel Blockers; Spider Venoms; Substantia Nigra; Synapses; Tetrodotoxin | 2005 |
Racemic resolution of RS-baclofen using lipase from Candida cylindracea.
Topics: Baclofen; Candida; Catalysis; gamma-Aminobutyric Acid; Lipase; Stereoisomerism; Substrate Specificity | 2001 |
HPLC conditions are critical for the detection of GABA by microdialysis.
Topics: Anesthetics, Local; Animals; Baclofen; Benzylamines; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microdialysis; Nipecotic Acids; Phosphinic Acids; Potassium; Rats; Rats, Wistar; Tetrodotoxin; Time Factors | 2005 |
Synaptically released GABA activates both pre- and postsynaptic GABA(B) receptors in the rat globus pallidus.
Topics: Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; In Vitro Techniques; Neural Inhibition; Neurons; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synapses; Synaptic Transmission; Time Factors | 2005 |
Anti-GAD antibodies and periodic alternating nystagmus.
Topics: Aged; Autoantibodies; Baclofen; Cerebellar Ataxia; Cerebellum; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Models, Neurological; Neural Inhibition; Nystagmus, Pathologic; Periodicity; Synaptic Transmission; Treatment Outcome | 2005 |
Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Calcium; Cerebellar Nuclei; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2005 |
Different function of pedunculopontine GABA and glutamate receptors in nucleus accumbens dopamine, pedunculopontine glutamate and operant discriminative behavior.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Brain Chemistry; Conditioning, Operant; Discrimination, Psychological; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesencephalon; Microdialysis; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Time Factors | 2005 |
Inhibition of mechanosensitivity in visceral primary afferents by GABAB receptors involves calcium and potassium channels.
Topics: Action Potentials; Animals; Baclofen; Calcium Channels; Calcium Channels, N-Type; Calcium Signaling; Esophagus; Ferrets; GABA Agonists; gamma-Aminobutyric Acid; Gastric Mucosa; Gastrointestinal Tract; Mechanoreceptors; Neural Inhibition; Neurons, Afferent; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, GABA-B; Stomach; Visceral Afferents | 2006 |
Spinal nerve ligation does not alter the expression or function of GABA(B) receptors in spinal cord and dorsal root ganglia of the rat.
Topics: Animals; Baclofen; Denervation; Disease Models, Animal; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Guanosine 5'-O-(3-Thiotriphosphate); Hyperalgesia; Ligation; Male; Neural Inhibition; Neuralgia; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Posterior Horn Cells; Presynaptic Terminals; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synaptic Transmission; Up-Regulation | 2006 |
GABA-induced calcium signaling in cultured enteric neurons is reinforced by activation of cholinergic pathways.
Topics: Acetylcholine; Animals; Baclofen; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hexamethonium; Isonicotinic Acids; Myenteric Plexus; Neurons; Nicotinic Antagonists; Ondansetron; Pyridoxal Phosphate; Serotonin Antagonists; Signal Transduction | 2006 |
Effects of baclofen on reserpine-induced vacuous chewing movements in mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Baclofen; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Mastication; Mice; Neural Inhibition; Receptors, GABA-B; Reserpine; Synaptic Transmission | 2006 |
Role of CGRP and GABA in the hypotensive effect of intrathecally administered anandamide to anesthetized rats.
Topics: Animals; Antihypertensive Agents; Arachidonic Acids; Baclofen; Benzoxazines; Bicuculline; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Spinal; Male; Morpholines; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Calcitonin Gene-Related Peptide; Time Factors | 2006 |
Beta and gamma range EEG power-spectrum correlation with spiking discharges in DBA/2J mice absence model: role of GABA receptors.
Topics: Alpha Rhythm; Animals; Baclofen; Beta Rhythm; Cerebral Cortex; Cognition; Cortical Synchronization; Delta Rhythm; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Mice, Inbred DBA; Morpholines; Receptors, GABA-B; Theta Rhythm | 2006 |
Modeling Starburst cells' GABA(B) receptors and their putative role in motion sensitivity.
Topics: Acetylcholine; Amacrine Cells; Animals; Baclofen; Bicuculline; Computer Simulation; Dendrites; Feedback, Physiological; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Models, Neurological; Motion Perception; Neural Inhibition; Receptors, GABA-B; Strychnine | 2006 |
Metabolic GHB precursor succinate binds to gamma-hydroxybutyrate receptors: characterization of human basal ganglia areas nucleus accumbens and globus pallidus.
Topics: Animals; Baclofen; Benzocycloheptenes; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Humans; Male; Models, Biological; Nucleus Accumbens; Postmortem Changes; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Receptors, Cell Surface; Succinic Acid; Synaptosomes; Tritium | 2006 |
Absence of GABA type A signaling in adult medial habenular neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Animals, Newborn; Baclofen; Bicuculline; Choline O-Acetyltransferase; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glycine Agents; Habenula; Immunohistochemistry; In Vitro Techniques; Isoenzymes; K Cl- Cotransporters; Male; Neural Inhibition; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Strychnine; Symporters | 2006 |
Survey of management of acquired nystagmus in the United Kingdom.
Topics: Amines; Baclofen; Cyclohexanecarboxylic Acids; Drug Utilization; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Health Care Surveys; Humans; Multiple Sclerosis; Neoplasms; Neurology; Nystagmus, Pathologic; Ophthalmology; Professional Practice; Referral and Consultation; Stroke; Treatment Outcome; United Kingdom; Vestibular Diseases | 2007 |
Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study.
Topics: Acetyltransferases; Analysis of Variance; Animals; Baclofen; Dose-Response Relationship, Radiation; Drug Delivery Systems; Electric Stimulation; Electromyography; Evoked Potentials, Motor; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression; H-Reflex; Immunohistochemistry; Male; Muscle Rigidity; Muscle Spasticity; Muscle, Skeletal; Neurologic Examination; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Rhizotomy; Spinal Cord Ischemia; Vesicular Glutamate Transport Protein 1; Vesicular Glutamate Transport Protein 2 | 2006 |
Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.
Topics: Acute Disease; Analgesics; Animals; Baclofen; Behavior, Animal; Chronic Disease; Disease Models, Animal; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neurons; Organophosphorus Compounds; Pain; Pain Measurement; Pain Threshold; Rats; Receptors, GABA-B; Synaptic Transmission; Time Factors; Ventral Thalamic Nuclei | 2006 |
Nucleus-specific abnormalities of GABAergic synaptic transmission in a genetic model of absence seizures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Epilepsy, Absence; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Intralaminar Thalamic Nuclei; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Receptors, GABA-A; Somatosensory Cortex; Synapses; Synaptic Transmission; Ventral Thalamic Nuclei | 2006 |
Differential effects of chronic amphetamine and baclofen administration on cAMP levels and phosphorylation of CREB in distinct brain regions of wild type and monoamine oxidase B-deficient mice.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Baclofen; Biogenic Monoamines; Brain; Central Nervous System Stimulants; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Drug Administration Schedule; GABA Agonists; gamma-Aminobutyric Acid; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoamine Oxidase; Neural Inhibition; Phosphorylation; Receptors, GABA-B; Synaptic Transmission; Up-Regulation | 2006 |
Opposite effects of presynaptic 5-HT3 receptor activation on spontaneous and action potential-evoked GABA release at hippocampal synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Indoles; Inhibitory Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Tropisetron | 2007 |
Characterization and restoration of altered inhibitory and excitatory control of micturition reflex in experimental autoimmune encephalomyelitis in rats.
Topics: Animals; Baclofen; Bicuculline; Cauda Equina; Efferent Pathways; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; gamma-Aminobutyric Acid; Glycine; Injections, Spinal; Lumbosacral Plexus; Models, Biological; Muscimol; Peripheral Nerves; Rats; Rats, Inbred Lew; Receptors, Glycine; Reflex, Abnormal; Spinal Cord; Strychnine; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive; Urinary Retention | 2007 |
Comparative effects of some hydrophilic excipients on the rate of gabapentin and baclofen lactamization in lyophilized formulations.
Topics: Amines; Anticonvulsants; Baclofen; beta-Cyclodextrins; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Cyclohexanecarboxylic Acids; Drug Stability; Excipients; Freeze Drying; Gabapentin; gamma-Aminobutyric Acid; Humidity; Kinetics; Lactams; Lactose; Mannitol; Models, Chemical; Molecular Structure; Parasympatholytics; Povidone; Raffinose; Technology, Pharmaceutical; Temperature; Thermogravimetry; Trehalose; Water | 2007 |
Orexin A in the rostrolateral hypothalamic area induces feeding by modulating GABAergic transmission.
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; Eating; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Male; Microdialysis; Muscimol; Neuropeptides; Orexins; Rats; Rats, Sprague-Dawley; Time Factors | 2006 |
Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.
Topics: Animals; Animals, Newborn; Baclofen; Brain; Cell Membrane; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down Syndrome; Excitatory Postsynaptic Potentials; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Mice; Mice, Neurologic Mutants; Neurons; Patch-Clamp Techniques; Potassium; Receptors, GABA-B; Synaptic Transmission; Trisomy | 2007 |
GABAA but not GABAB receptors in the rostral anterior cingulate cortex selectively modulate pain-induced escape/avoidance behavior.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Escape Reaction; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gyrus Cinguli; Male; Microinjections; Muscimol; Pain; Pain Threshold; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2007 |
Effects of GABA(A) and GABA(B) agonists on interhemispheric inhibition in man.
Topics: Adult; Baclofen; Cerebral Cortex; Corpus Callosum; Electric Stimulation; Female; GABA Agonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Midazolam; Nerve Net; Neural Inhibition; Neural Pathways; Receptors, GABA-A; Receptors, GABA-B; Reference Values; Synaptic Membranes; Synaptic Transmission | 2007 |
Electrically evoked GABA release in rat hippocampus CA1 region and its changes during kindling epileptogenesis.
Topics: Animals; Anticonvulsants; Baclofen; Electric Stimulation; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Nipecotic Acids; Rats; Rats, Wistar | 2007 |
Attenuation of cocaine-seeking by GABA B receptor agonists baclofen and CGP44532 but not the GABA reuptake inhibitor tiagabine in baboons.
Topics: Animals; Appetitive Behavior; Baclofen; Cocaine-Related Disorders; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Motivation; Nipecotic Acids; Organophosphonates; Papio anubis; Phosphinic Acids; Self Administration; Tiagabine | 2007 |
Uptake and release of [(3)H]GABA in human dental pulp.
Topics: Adult; Autoreceptors; Baclofen; Dental Pulp; Electric Stimulation; Female; GABA Agents; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Male; Morpholines; Nipecotic Acids; Oximes; Radiopharmaceuticals; Receptors, GABA; Time Factors; Tritium | 2007 |
GABAergic modulation of developing pedunculopontine nucleus.
Topics: Action Potentials; Aging; Animals; Baclofen; GABA Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Muscimol; Neural Inhibition; Neural Pathways; Pedunculopontine Tegmental Nucleus; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reticular Formation; Sleep, REM; Sodium Channel Blockers | 2007 |
Pentobarbital enhances gamma-aminobutyric acid-mediated excitation without altering synaptic plasticity in rat hippocampus.
Topics: Adjuvants, Anesthesia; Animals; Baclofen; Bicarbonates; Bicuculline; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neuronal Plasticity; Neurons; Pentobarbital; Rats; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Time Factors | 2007 |
Differential involvement of ventral tegmental GABA(A) and GABA(B) receptors in the regulation of the nucleus accumbens dopamine response to stress.
Topics: Animals; Baclofen; Bicuculline; Dopamine; Dose-Response Relationship, Drug; Electrochemistry; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, GABA; Stress, Physiological; Ventral Tegmental Area | 2007 |
The effects of GABA agonists on glutamic acid decarboxylase, GABA-transaminase, activin, salmon gonadotrophin-releasing hormone and tyrosine hydroxylase mRNA in the goldfish (Carassius auratus) neuroendocrine brain.
Topics: 4-Aminobutyrate Transaminase; Activins; Animals; Baclofen; Female; Fish Proteins; GABA Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Goldfish; Gonadotropin-Releasing Hormone; Hypothalamus; Luteinizing Hormone; Muscimol; Receptors, GABA; RNA, Messenger; Telencephalon; Tyrosine 3-Monooxygenase | 2007 |
Presynaptic inhibition of excitatory afferents to hilar mossy cells.
Topics: Animals; Baclofen; Cholinergic Agents; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Mossy Fibers, Hippocampal; Neural Inhibition; Neurons, Afferent; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Synaptic Transmission | 2007 |
Convulsions induced by methylmalonic acid are associated with glutamic acid decarboxylase inhibition in rats: a role for GABA in the seizures presented by methylmalonic acidemic patients?
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Male; Methylmalonic Acid; Muscimol; Rats; Rats, Wistar; Seizures | 2007 |
Posterior hypothalamic GABAergic mediation of hippocampal theta in the cat.
Topics: Animals; Baclofen; Bicuculline; Cats; Electroencephalography; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus, Posterior; Muscimol; Rats; Theta Rhythm | 2007 |
Dominant role of GABAB2 and Gbetagamma for GABAB receptor-mediated-ERK1/2/CREB pathway in cerebellar neurons.
Topics: Animals; Baclofen; Cell Line; Cerebellum; Cyclic AMP Response Element-Binding Protein; Extracellular Signal-Regulated MAP Kinases; gamma-Aminobutyric Acid; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Phosphorylation; Protein Subunits; Receptors, GABA-B | 2007 |
Effect of GABAergic substances on firing rate and thermal coefficient of hypothalamic neurons in the juvenile chicken.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Body Temperature Regulation; Chickens; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Temperature; Time Factors | 2007 |
GABAergic modulation of binge-like ethanol intake in C57BL/6J mice.
Topics: Alcoholism; Animals; Baclofen; Central Nervous System Depressants; Darkness; Dose-Response Relationship, Drug; Ethanol; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Postural Balance | 2007 |
The Cav3.2/alpha1H T-type Ca2+ current is a molecular determinant of excitatory effects of GABA in adult sensory neurons.
Topics: Animals; Baclofen; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; GABA Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Membrane Potentials; Mice; Mice, Knockout; Muscimol; Neurons, Afferent; Nickel; Patch-Clamp Techniques | 2007 |
A spinal muscarinic M2 receptor-GABAergic disinhibition pathway that modulates peripheral inflammation in mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Anti-Inflammatory Agents; Autonomic Fibers, Preganglionic; Baclofen; Catecholamines; Cell Proliferation; Exudates and Transudates; GABA Antagonists; gamma-Aminobutyric Acid; Image Interpretation, Computer-Assisted; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred ICR; Neural Pathways; Neurons; Receptor, Muscarinic M2; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 2007 |
High-frequency afferent stimulation induces long-term potentiation of field potentials in the ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Animals; Animals, Newborn; Baclofen; Dopamine; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Ventral Tegmental Area | 2008 |
GABA(B) receptor activation inhibits dopamine D1 receptor-mediated facilitation of [(3)H]GABA release in substantia nigra pars reticulata.
Topics: Animals; Baclofen; Benzazepines; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Dopamine Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, GABA-B; Reserpine; Substantia Nigra | 2007 |
GABAergic medications for treating alcohol dependence.
Topics: Alcoholism; Baclofen; Drug Therapy, Combination; GABA Agonists; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Receptors, GABA-B; Substance Withdrawal Syndrome; Temperance | 2007 |
The involvement of the substantia nigra pars reticulata in hypoglycemic seizures.
Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Fasting; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hypoglycemia; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Seizures; Substantia Nigra | 2007 |
Activation of postsynaptic GABAB receptors modulates the bursting pattern and synaptic activity of olfactory bulb juxtaglomerular neurons.
Topics: Action Potentials; Animals; Baclofen; Excitatory Postsynaptic Potentials; Female; GABA Agonists; gamma-Aminobutyric Acid; Interneurons; Male; Neural Inhibition; Neurons; Neuropil; Olfactory Bulb; Olfactory Nerve; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Smell; Synapses; Synaptic Membranes; Synaptic Transmission | 2008 |
Sustained granule cell activity disinhibits juvenile mouse cerebellar stellate cells through presynaptic mechanisms.
Topics: Animals; Baclofen; Cerebral Cortex; Evoked Potentials; GABA Agonists; gamma-Aminobutyric Acid; Kainic Acid; Mice; Mice, Inbred C57BL; Presynaptic Terminals; Receptors, AMPA; Receptors, GABA-B; Stellate Ganglion; Synapses; Synaptic Transmission | 2008 |
A case report on idiopathic recurrent priapism.
Topics: Adult; Amines; Androgen Antagonists; Baclofen; Cyclohexanecarboxylic Acids; Cyproterone Acetate; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Muscle Relaxants, Central; Priapism; Secondary Prevention | 2007 |
GABA B receptor is a novel drug target for pancreatic cancer.
Topics: Adrenergic beta-Agonists; Baclofen; Blotting, Western; Bromodeoxyuridine; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP; Enzyme Activation; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Isoproterenol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Receptors, GABA; RNA Interference; Signal Transduction | 2008 |
The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Baclofen; Benzhydryl Compounds; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Microdialysis; Nucleus Accumbens; Phosphoserine; Rats; Rats, Long-Evans; Tetrodotoxin | 2008 |
Unexpected benefit of propofol in stiff-person syndrome.
Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Infusion Pumps, Implantable; Injections, Intravenous; Injections, Spinal; Muscle Spasticity; Propofol; Stiff-Person Syndrome | 2008 |
Co-transmission of dopamine and GABA in periglomerular cells.
Topics: Analysis of Variance; Animals; Animals, Newborn; Baclofen; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; In Vitro Techniques; Interneurons; Mice; Mice, Inbred DBA; Mice, Transgenic; Olfactory Bulb; Olfactory Receptor Neurons; Sulpiride; Tyrosine 3-Monooxygenase | 2008 |
Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats.
Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Azabicyclo Compounds; Baclofen; Benzodiazepines; Bicuculline; Brain; Cyclohexanecarboxylic Acids; Discrimination Learning; Dose-Response Relationship, Drug; GABA Agents; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Generalization, Stimulus; Hypnotics and Sedatives; Injections, Intraperitoneal; Isoxazoles; Male; Nipecotic Acids; Piperazines; Pyridines; Rats; Thiophenes; Tiagabine; Zolpidem | 2008 |
Evidence that gamma-aminobutyric acid is part of the neural circuit mediating estradiol negative feedback in anestrous ewes.
Topics: Anestrus; Animals; Baclofen; Bicuculline; Dopamine; Estradiol; Feedback; Female; gamma-Aminobutyric Acid; Muscimol; Neurons; Ovariectomy; Sheep | 2008 |
Involvement of pallidotegmental neurons in methamphetamine- and MK-801-induced impairment of prepulse inhibition of the acoustic startle reflex in mice: reversal by GABAB receptor agonist baclofen.
Topics: Animals; Baclofen; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Inbred ICR; Neural Inhibition; Neural Pathways; Pons; Proto-Oncogene Proteins c-fos; Receptors, GABA-B; Reticular Formation; Sensory Gating; Synaptic Transmission | 2008 |
Cholinergic and GABAergic innervation regulate activity of electrogenic ionic pump in earthworm somatic muscle cells.
Topics: Animals; Atropine; Baclofen; Carbachol; Cholinergic Fibers; gamma-Aminobutyric Acid; Ion Pumps; Membrane Potentials; Muscle Cells; Norepinephrine; Oligochaeta; Ouabain; Sodium-Potassium-Exchanging ATPase; Tubocurarine | 2007 |
The CGP7930 analogue 2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol (BSPP) potentiates baclofen action at GABA(B) autoreceptors.
Topics: Animals; Baclofen; Drug Evaluation, Preclinical; Drug Synergism; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Morpholines; Neocortex; Organ Culture Techniques; Phenols; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spiro Compounds; Tritium | 2008 |
Propofol for stiff-person syndrome: learning new tricks from an old dog.
Topics: Aged; Autoantibodies; Baclofen; Diazepam; Drug Resistance; Female; GABA Agonists; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Humans; Muscle Spasticity; Propofol; Stiff-Person Syndrome | 2008 |
The effects of electroconvulsive therapy on GABAergic function in major depressive patients.
Topics: Adult; Baclofen; Depressive Disorder, Major; Electroconvulsive Therapy; Female; GABA Agonists; gamma-Aminobutyric Acid; Human Growth Hormone; Humans; Male; Middle Aged | 2008 |
GABA(B) receptor modulation of feedforward inhibition through hippocampal neurogliaform cells.
Topics: Action Potentials; Animals; Baclofen; Calcium; Calcium Signaling; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Inhibitory Postsynaptic Potentials; Interneurons; Neural Inhibition; Neural Pathways; Neuroglia; Organ Culture Techniques; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission | 2008 |
Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem.
Topics: Acoustic Stimulation; Action Potentials; Anesthetics, Local; Animals; Animals, Newborn; Auditory Pathways; Baclofen; Dose-Response Relationship, Drug; Ear; Egtazic Acid; Electric Stimulation; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Lidocaine; Models, Molecular; Neural Inhibition; Neurons; Olivary Nucleus; Organophosphorus Compounds; Patch-Clamp Techniques; Receptors, GABA-B; Sound Localization; Synaptic Transmission | 2008 |
Activation of the GABA(A) receptor ameliorates the cochlear excitotoxicity caused by kainic acid in the guinea pig.
Topics: Acoustics; Action Potentials; Animals; Baclofen; Bicuculline; Cochlea; Electrophysiology; GABA Agonists; gamma-Aminobutyric Acid; Glutamine; Guinea Pigs; Kainic Acid; Muscimol; Neurons; Receptors, GABA-A | 2008 |
Receptor activation involving positive allosteric modulation, unlike full agonism, does not result in GABAB receptor desensitization.
Topics: Allosteric Regulation; Animals; Baclofen; Benzoates; Biophysical Phenomena; Calcium; Cells, Cultured; Cerebral Cortex; Chlorocebus aethiops; Cyclic AMP; Cyclopentanes; Dose-Response Relationship, Drug; Embryo, Mammalian; GABA Agonists; gamma-Aminobutyric Acid; Humans; Mice; Mice, Inbred BALB C; Neurons; Organophosphorus Compounds; Pyrimidines; Receptors, GABA-B | 2008 |
GABAergic mediation of stress-induced secretion of corticosterone and oxytocin, but not prolactin, by the hypothalamic paraventricular nucleus.
Topics: Animals; Baclofen; Bicuculline; Corticosterone; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Oxytocin; Paraventricular Hypothalamic Nucleus; Prolactin; Rats; Rats, Wistar; Stress, Psychological | 2008 |
Baclofen does not counteract the acute effects of ethanol on flash-evoked potentials in Long-Evans rats.
Topics: Acute Disease; Alcohol-Induced Disorders, Nervous System; Animals; Arousal; Baclofen; Drug Synergism; Ethanol; Evoked Potentials, Visual; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Photic Stimulation; Rats; Rats, Long-Evans; Reaction Time; Receptors, GABA-B; Superior Colliculi; Time Factors; Visual Cortex | 2008 |
The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons.
Topics: Animals; Animals, Newborn; Baclofen; Benzoxazines; Benzylamines; Calcium; Central Nervous System Depressants; Cerebellum; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Ethanol; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Morpholines; Naphthalenes; Patch-Clamp Techniques; Phosphinic Acids; Protein Kinase C; Purkinje Cells; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2008 |
GABA-B(1) receptors are coupled to the ERK1/2 MAP kinase pathway in the absence of GABA-B(2) subunits.
Topics: Animals; Baclofen; Cell Line; Extracellular Signal-Regulated MAP Kinases; GABA Agents; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Pertussis Toxin; Phosphorylation; Protein Multimerization; Rats; Receptors, GABA-B | 2009 |
Source, topography and excitatory effects of GABAergic innervation in cockroach salivary glands.
Topics: Analysis of Variance; Animals; Baclofen; Benzylamines; Electrophysiology; Fluorescent Antibody Technique; GABA Agonists; gamma-Aminobutyric Acid; Neurons; Organophosphorus Compounds; Periplaneta; Phosphinic Acids; Salivary Glands | 2009 |
Tibolone rapidly attenuates the GABAB response in hypothalamic neurones.
Topics: Animals; Baclofen; Estrenes; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Protein alpha Subunits, Gq-G11; Guinea Pigs; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Structure; Neurons; Norpregnenes; Patch-Clamp Techniques; Pyrrolidinones; Receptors, GABA-B; Signal Transduction; Type C Phospholipases | 2008 |
Changes in the properties of allosteric and orthosteric GABAB receptor ligands after a continuous, desensitizing agonist pretreatment.
Topics: Allosteric Regulation; Animals; Baclofen; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Cyclopentanes; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Pyrimidines; Rats; Receptors, GABA-B | 2009 |
Gamma-aminobutyric acid: something old, something new for bronchodilation.
Topics: Animals; Baclofen; Bronchoconstriction; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Humans; Receptors, GABA-B | 2009 |
Human cord blood-derived hematopoietic and neural-like stem/progenitor cells are attracted by the neurotransmitter GABA.
Topics: AC133 Antigen; Antigens, CD; Baclofen; Bicuculline; Cell Differentiation; Cell Line; Cells, Cultured; Chemotaxis; Colony-Forming Units Assay; Fetal Blood; Flow Cytometry; Fluorescent Antibody Technique; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glycoproteins; Hematopoietic Stem Cells; Humans; Neurons; Peptides; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells | 2009 |
The incidence and management of tolerance in intrathecal baclofen therapy.
Topics: Adolescent; Adult; Aged; Baclofen; Cohort Studies; Dose-Response Relationship, Drug; Drug Tolerance; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Infusion Pumps, Implantable; Injections, Spinal; Male; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Neural Inhibition; Receptors, GABA-B; Retrospective Studies; Spinal Cord; Spinal Cord Injuries; Young Adult | 2009 |
Differential effects of GABAB autoreceptor activation on ethanol potentiation of local and lateral paracapsular GABAergic synapses in the rat basolateral amygdala.
Topics: Amygdala; Animals; Autoreceptors; Baclofen; Ethanol; GABA Modulators; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Male; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission | 2009 |
Impaired function of GABA(B) receptors in tissues from pharmacoresistant epilepsy patients.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Drug Resistance; Epilepsy; Epilepsy, Temporal Lobe; Excitatory Postsynaptic Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Immunohistochemistry; Mice; Neurons; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-B; Synaptic Transmission | 2009 |
Pharmacological characterization of harmaline-induced tremor activity in mice.
Topics: Affect; Animals; Anticonvulsants; Baclofen; Behavior, Animal; Benzazepines; Carbolines; Chlordiazepoxide; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamates; Harmaline; Lithium Chloride; Male; Mice; Mice, Inbred ICR; Muscimol; Neurotransmitter Agents; Piperazines; Propranolol; Raclopride; Receptors, Glutamate; Sodium Oxybate; Tremor | 2009 |
Renoprotective effects of gamma-aminobutyric acid on ischemia/reperfusion-induced renal injury in rats.
Topics: Animals; Baclofen; Benzylamines; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Male; Neurons; Norepinephrine; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sympathetic Nervous System; Time Factors | 2009 |
Intrathecal administration of GABA agonists in the vegetative state.
Topics: Adolescent; Baclofen; Child; GABA Agents; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Male; Neurologic Examination; Persistent Vegetative State; Recovery of Function; Time Factors; Tomography, X-Ray Computed | 2009 |
Basolateral amygdala modulates terminal dopamine release in the nucleus accumbens and conditioned responding.
Topics: Amygdala; Animals; Baclofen; Conditioning, Operant; Data Interpretation, Statistical; Dopamine; Electrochemistry; GABA Agonists; gamma-Aminobutyric Acid; Male; Microinjections; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Signal Transduction; Ventral Tegmental Area | 2010 |
Alterations in excitatory and inhibitory brainstem interneuronal circuits after severe spinal cord injury.
Topics: Adult; Aged; Baclofen; Blinking; Brain Stem; Excitatory Postsynaptic Potentials; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Inhibitory Postsynaptic Potentials; Interneurons; Male; Middle Aged; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Physical Stimulation; Reaction Time; Recovery of Function; Sensory Gating; Spinal Cord Injuries; Synaptic Transmission; Young Adult | 2010 |
Neurotransmitters in coma, vegetative and minimally conscious states, pharmacological interventions.
Topics: Antidepressive Agents, Tricyclic; Baclofen; Coma; Dopamine Agents; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Biological; Neurotransmitter Agents; Persistent Vegetative State; Pyridines; Zolpidem | 2010 |
Type B GABA receptors contribute to the restoration of balance during vestibular compensation in mice.
Topics: Adaptation, Physiological; Animals; Ataxia; Baclofen; Benzoates; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Lameness, Animal; Male; Mice; Mice, Inbred C57BL; Phenols; Phosphinic Acids; Postural Balance; Receptors, GABA-B; Recovery of Function; Reflex; Vestibular Nucleus, Lateral; Vestibule, Labyrinth | 2010 |
[Changes in the psycho-emotional state under conditions of suppressed immunogenesis, the correction of the disorders with GABA-positive means].
Topics: Animals; Baclofen; Behavior, Animal; Cyclophosphamide; Emotions; Female; GABA Agonists; gamma-Aminobutyric Acid; Grooming; Immunity; Male; Mice; Mice, Inbred CBA; Rats; Rats, Wistar | 2010 |
Plasticity of postsynaptic, but not presynaptic, GABAB receptors in SSADH deficient mice.
Topics: Adenosine; Animals; Baclofen; Disease Models, Animal; GABA Antagonists; gamma-Aminobutyric Acid; Mice; Mice, Knockout; Neuronal Plasticity; Organ Culture Techniques; Patch-Clamp Techniques; Presynaptic Terminals; Receptors, GABA-B; Succinate-Semialdehyde Dehydrogenase; Synaptic Transmission | 2010 |
Basal GABA regulates GABA(B)R conformation and release probability at single hippocampal synapses.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Animals, Newborn; Baclofen; CA1 Region, Hippocampal; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agents; gamma-Aminobutyric Acid; In Vitro Techniques; Microscopy, Confocal; Neurons; Nipecotic Acids; Organophosphorus Compounds; Potassium Chloride; Presynaptic Terminals; Probability; Protein Conformation; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Synapses; Tetrodotoxin | 2010 |
GABA-A and GABA-B receptors mediate feeding elicited by the GABA-B agonist baclofen in the ventral tegmental area and nucleus accumbens shell in rats: reciprocal and regional interactions.
Topics: Animals; Baclofen; Feeding Behavior; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Ventral Tegmental Area | 2010 |
Involvement of GABAergic transmission in the midbrain ventral tegmental area in the regulation of hippocampal theta rhythm.
Topics: Animals; Baclofen; Bicuculline; Electroencephalography; Fourier Analysis; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Rats; Rats, Wistar; Theta Rhythm; Ventral Tegmental Area | 2010 |
Identification and modulation of voltage-gated Ca2+ currents in zebrafish Rohon-Beard neurons.
Topics: Animals; Animals, Genetically Modified; Baclofen; Calcium Channels; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Models, Animal; Neurotransmitter Agents; Patch-Clamp Techniques; Sensory Receptor Cells; Zebrafish | 2011 |
[Pharmacological treatment of nystagmus].
Topics: 4-Aminopyridine; Amines; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dopamine Agents; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Muscle Relaxants, Central; Nystagmus, Pathologic; Potassium Channel Blockers | 2011 |
Pharmacological actions of oximino-propofol analogues at GABA(B) autoreceptors.
Topics: Animals; Autoreceptors; Baclofen; Electric Stimulation; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Morpholines; Neocortex; Oximes; Phenols; Propofol; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Tritium | 2011 |
GABAB receptor-mediated tonic inhibition of noradrenergic A7 neurons in the rat.
Topics: Analysis of Variance; Animals; Anisoles; Baclofen; Barium; Bee Venoms; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation; In Vitro Techniques; Lysine; Male; Morpholines; Neural Inhibition; Neurons; Nipecotic Acids; Norepinephrine; Organophosphorus Compounds; Oximes; Patch-Clamp Techniques; Pons; Potassium Channel Blockers; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; RNA, Messenger | 2011 |
Addiction research. Anonymous alcoholic bankrolls trial of controversial therapy.
Topics: Alcoholism; Baclofen; Controlled Clinical Trials as Topic; Financial Support; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans | 2011 |
Time-dependent effect of GABA on glucose-stimulated insulin secretion from isolated islets in rat.
Topics: Animals; Baclofen; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Wistar; Time Factors | 2011 |
Mechanisms underlying the renoprotective effect of GABA against ischemia/reperfusion-induced renal injury in rats.
Topics: Acute Kidney Injury; Animals; Baclofen; Benzylamines; Bicuculline; Blood Urea Nitrogen; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intravenous; Injections, Intraventricular; Kidney; Kidney Function Tests; Male; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reperfusion Injury; Sympathetic Nervous System | 2011 |
Activation of presynaptic GABAB receptors modulates GABAergic and glutamatergic inputs to the medial geniculate body.
Topics: Aging; Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Models, Animal; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Presynaptic; Synaptic Transmission | 2011 |
GABAergic neural activity involved in salicylate-induced auditory cortex gain enhancement.
Topics: Acoustic Stimulation; Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Auditory Cortex; Baclofen; GABA Agents; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle; Vigabatrin | 2011 |
Stiff person syndrome and pregnancy.
Topics: Adult; Amines; Baclofen; Cesarean Section; Cyclohexanecarboxylic Acids; Diazepam; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Muscle Relaxants, Central; Prednisone; Pregnancy; Spasm; Stiff-Person Syndrome; Treatment Outcome | 2011 |
GABAergic signaling in primary lens epithelial and lentoid cells and its involvement in intracellular Ca2+ modulation.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Calcium; Calcium Channels; Calcium Signaling; Cell Differentiation; Epithelial Cells; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Lens, Crystalline; Mice; Muscimol; Primary Cell Culture; Receptors, GABA-A; Receptors, GABA-B | 2011 |
Pharmacological tests of hypotheses for acquired pendular nystagmus.
Topics: Amines; Baclofen; Cerebellar Cortex; Cyclohexanecarboxylic Acids; Eye Movements; Gabapentin; gamma-Aminobutyric Acid; Humans; Memantine; Models, Neurological; Multiple Sclerosis; Myoclonus; Nystagmus, Pathologic; Olivary Nucleus | 2011 |
In vivo neurochemical evidence that newly synthesised GABA activates GABA(B), but not GABA(A), receptors on dopaminergic nerve endings in the nucleus accumbens of freely moving rats.
Topics: Allylglycine; Animals; Baclofen; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Microdialysis; Muscimol; Nerve Endings; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2012 |
Pharmacology of intracisternal or intrathecal glycine, muscimol, and baclofen in strychnine-induced thermal hyperalgesia of mice.
Topics: Animals; Baclofen; Drug Delivery Systems; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Muscimol; Pain Threshold; Random Allocation; Strychnine | 2011 |
Peripheral and spinal GABAergic regulation of incisional pain in rats.
Topics: Animals; Baclofen; Behavior, Animal; Chronic Pain; gamma-Aminobutyric Acid; Hyperalgesia; Muscimol; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 2012 |
Effects of GABAB receptor agonists and antagonists on glycemia regulation in mice.
Topics: Animals; Baclofen; Basal Metabolism; Blood Glucose; Body Weight; Eating; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Glucose Tolerance Test; Homeostasis; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Protein Subunits; Receptors, GABA-B; RNA, Messenger; Time Factors | 2012 |
[Influence of GABA derivatives on some indices of lipid peroxidation in immunocompetent organs under experimental immunopathology conditions].
Topics: Animals; Antioxidants; Baclofen; Catalase; Cyclophosphamide; gamma-Aminobutyric Acid; Immunosuppression Therapy; Immunosuppressive Agents; Lipid Peroxidation; Lipopolysaccharides; Male; Malondialdehyde; Organ Specificity; Oxidative Stress; Piracetam; Rats; Rats, Wistar; Spleen; Thymus Gland | 2011 |
Lateral hypothalamic area mediated the aggravated effect of microinjection of Baclofen into cerebellar fastigial nucleus on stress gastric mucosal damage in rats.
Topics: Animals; Apoptosis; Baclofen; Cell Proliferation; Cerebellar Nuclei; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Ganglionectomy; Gastric Acid; Gastric Mucosa; Gastrointestinal Diseases; Hypothalamic Area, Lateral; Microinjections; Neural Pathways; Rats; Receptors, GABA; Stress, Physiological | 2012 |
Changes in GABA and GABA(B) receptor expressions are involved in neuropathy in the rat cuneate nucleus following median nerve transection.
Topics: Animals; Baclofen; Electric Stimulation; GABA Antagonists; Gait; gamma-Aminobutyric Acid; Ganglia, Spinal; Male; Median Nerve; Median Neuropathy; Medulla Oblongata; Neuropeptide Y; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2012 |
Methamphetamine-evoked depression of GABA(B) receptor signaling in GABA neurons of the VTA.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bacterial Proteins; Central Nervous System Stimulants; Channelrhodopsins; Dopamine; Dopamine Agents; Down-Regulation; Drug Interactions; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Green Fluorescent Proteins; Homeodomain Proteins; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Immunoelectron; Neurons; Organophosphorus Compounds; Phosphorylation; Receptors, GABA-A; Transcription Factors; Ventral Tegmental Area | 2012 |
Involvement of hypothalamic periventricular GABAergic nerves in the central pressor response to clonidine in freely-moving conscious rats.
Topics: Animals; Antihypertensive Agents; Baclofen; Bicuculline; Blood Pressure; Clonidine; Excitatory Amino Acid Antagonists; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Heart Rate; Hypothalamus; Kynurenic Acid; Male; Muscimol; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Glutamate | 2012 |
Presynaptic mGlu7 receptors control GABA release in mouse hippocampus.
Topics: Adenylyl Cyclase Inhibitors; Aminobutyrates; Animals; Baclofen; Benzhydryl Compounds; Benzoates; Benzylamines; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Exocytosis; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Hippocampus; Imines; Mice; Phosphinic Acids; Potassium Chloride; Pyridones; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synaptosomes; Syntaxin 1; Vesicular Inhibitory Amino Acid Transport Proteins | 2013 |
[Respiratory reactions on microinjections of GABA and baclofen into the Bötzinger complex and the pre-Bötzinger complex in rats].
Topics: Animals; Baclofen; Exhalation; Female; gamma-Aminobutyric Acid; Inhalation; Male; Medulla Oblongata; Microinjections; Muscle Relaxants, Central; Rats; Respiratory Rate; Tidal Volume | 2012 |
Baclofen administration alters fear extinction and GABAergic protein levels.
Topics: Amygdala; Animals; Baclofen; Conditioning, Psychological; Cues; Extinction, Psychological; Fear; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle | 2012 |
Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system.
Topics: Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Lamotrigine; Lithium Carbonate; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Obsessive-Compulsive Disorder; Receptors, GABA-A; Triazines; Valproic Acid | 2013 |
Phenibut dependence.
Topics: Adult; Baclofen; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Male; Russia; Substance-Related Disorders | 2013 |
GABAergic synaptic inputs of locus coeruleus neurons in wild-type and Mecp2-null mice.
Topics: Animals; Baclofen; Female; GABA Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Locus Coeruleus; Male; Membrane Potentials; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscimol; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Presynaptic Terminals; Receptors, GABA-A; Receptors, GABA-B; Rett Syndrome; Synaptic Membranes; Synaptic Transmission | 2013 |
Release of a single neurotransmitter from an identified interneuron coherently affects motor output on multiple time scales.
Topics: Animals; Aplysia; Baclofen; Eating; Excitatory Postsynaptic Potentials; Feeding Behavior; GABA Antagonists; GABA-B Receptor Agonists; GABAergic Neurons; gamma-Aminobutyric Acid; Ganglia, Invertebrate; Interneurons; Motor Activity; Picrotoxin; Time Factors | 2013 |
Co-application of the GABAB receptor agonist, baclofen, and the mGlu receptor agonist, L-CCG-I, facilitates [(3)H]GABA release from rat cortical nerve endings.
Topics: Amino Acids, Dicarboxylic; Animals; Baclofen; Cerebral Cortex; Chelating Agents; Estrenes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Male; Neurons; Organophosphorus Compounds; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Synaptosomes; Time Factors | 2013 |
γ-Aminobutyric acid regulates both the survival and replication of human β-cells.
Topics: Animals; Apoptosis; Baclofen; Cell Survival; Diabetes Mellitus, Experimental; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Heterografts; Humans; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred NOD; Muscimol; Receptors, GABA-A | 2013 |
Evaluation of two modified quick, easy, cheap, effective, rugged and safe (QuEChERS) sample preparation methods for the analysis of baclofen and gabapentin in feeds by liquid chromatography tandem mass spectrometry.
Topics: Acetonitriles; Amines; Animal Feed; Baclofen; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Formates; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Mass Spectrometry; Methanol; Reproducibility of Results; Time Factors; Water | 2014 |
Painful traumatic trigeminal neuropathy: an open study on the pharmacotherapeutic response to stepped treatment.
Topics: Amines; Amitriptyline; Analgesics; Analgesics, Non-Narcotic; Baclofen; Carbamazepine; Clinical Protocols; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Combinations; Duloxetine Hydrochloride; Female; Follow-Up Studies; GABA-B Receptor Agonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Medical Records; Middle Aged; Nortriptyline; Pain; Pain Measurement; Pregabalin; Prognosis; Prospective Studies; Thiophenes; Treatment Outcome; Trigeminal Nerve Injuries; Trigeminal Neuralgia | 2014 |
Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes.
Topics: Animals; Autoreceptors; Baclofen; Calcineurin Inhibitors; Corpus Striatum; Dopamine; Female; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred C57BL; Potassium Chloride; Presynaptic Terminals; Protein Kinase C; Pyrethrins; Receptors, GABA-B; Receptors, Nicotinic; Synaptosomes; Time Factors | 2014 |
Successful treatment of excessive supragastric belching by combination of pregabalin and baclofen.
Topics: Anticonvulsants; Baclofen; Drug Therapy, Combination; Eructation; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Muscle Relaxants, Central; Pregabalin; Treatment Outcome | 2015 |
Misuse of the γ-aminobutyric acid analogues baclofen, gabapentin and pregabalin in the UK.
Topics: Adolescent; Adult; Amines; Baclofen; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Humans; Illicit Drugs; Male; Middle Aged; Pregabalin; Prescription Drug Misuse; United Kingdom; Young Adult | 2014 |
Pharmacological actions of thymol and an analogue at GABAB autoreceptors.
Topics: Animals; Autoreceptors; Baclofen; Butylated Hydroxytoluene; Dose-Response Relationship, Drug; GABA Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Morpholines; Neocortex; Phenols; Rats; Receptors, GABA-B; Thymol | 2014 |
Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice.
Topics: Animals; Anxiety; Baclofen; Cell Movement; Depression; Embryo, Mammalian; Female; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression; Hypothalamo-Hypophyseal System; Immobilization; Male; Maze Learning; Mice; Mice, Transgenic; Paraventricular Hypothalamic Nucleus; Phosphinic Acids; Pituitary-Adrenal System; Pregnancy; Propanolamines; Protein Subunits; Psychomotor Agitation; Receptors, GABA-B; Sex Factors; Stress, Psychological; Tissue Culture Techniques | 2014 |
Nerve regenerative effects of GABA-B ligands in a model of neuropathic pain.
Topics: Animals; Baclofen; gamma-Aminobutyric Acid; Gene Expression; Humans; Hyperalgesia; Ligands; Myelin Proteins; Myelin Sheath; Nerve Regeneration; Neuralgia; Rats; Sciatic Nerve; Sciatic Neuropathy | 2014 |
GABA protects pancreatic beta cells against apoptosis by increasing SIRT1 expression and activity.
Topics: Animals; Apoptosis; Baclofen; Cell Line, Tumor; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Insulin-Secreting Cells; Muscimol; NAD; Picrotoxin; Primary Cell Culture; Rats; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; Sirtuin 1; Transcription Factor RelA | 2014 |
Pharmacological characterization of GABAB receptor subtypes assembled with auxiliary KCTD subunits.
Topics: Allosteric Regulation; Animals; Baclofen; Cells, Cultured; CHO Cells; Cricetulus; Cyclopentanes; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Modulators; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; HEK293 Cells; Hippocampus; Humans; Mice; Neurons; Potassium; Pyrimidines; Rats; Receptors, GABA-B; Recombinant Proteins | 2015 |
Prefrontal cortical GABA modulation of spatial reference and working memory.
Topics: Animals; Baclofen; Bicuculline; Discrimination, Psychological; GABA Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Maze Learning; Memory, Short-Term; Muscimol; Prefrontal Cortex; Rats, Long-Evans; Receptors, GABA-A; Spatial Memory | 2014 |
[Modulation of GABA- and kainate-activated currents by metabotropic receptors in isolated rat cortical neurons].
Topics: Animals; Baclofen; Cycloleucine; Excitatory Amino Acid Agonists; Female; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Kainic Acid; Male; Neuroprotective Agents; Phosphinic Acids; Propanolamines; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2014 |
Isovaline does not activate GABA(B) receptor-coupled potassium currents in GABA(B) expressing AtT-20 cells and cultured rat hippocampal neurons.
Topics: Analysis of Variance; Animals; Baclofen; Cell Line; Cells, Cultured; Female; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; Hippocampus; Male; Membrane Potentials; Mice; Microscopy, Confocal; Neurons; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Rats, Sprague-Dawley; Receptors, GABA-B; Valine | 2015 |
Electrophysiology of GABAergic transmission of single intergeniculate leaflet neurons in rat.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Geniculate Bodies; In Vitro Techniques; Neurons; Rats; Sodium Channel Blockers; Statistics, Nonparametric; Suprachiasmatic Nucleus; Synaptic Transmission; Tetrodotoxin | 2015 |
Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice.
Topics: Aggression; Animals; Baclofen; Dorsal Raphe Nucleus; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Mice, Knockout; Microinjections; Prefrontal Cortex; Receptors, GABA-B; Serotonergic Neurons | 2015 |
GABA acting on GABAB receptors located in a medullary pain facilitatory area enhances nociceptive behaviors evoked by intraplantar formalin injection.
Topics: Animals; Baclofen; Disease Models, Animal; Formaldehyde; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Neurons; Nociception; Nociceptors; Organophosphorus Compounds; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-B; Reticular Formation | 2015 |
The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Buspirone; Conditioning, Classical; Dose-Response Relationship, Drug; Fear; Fever; GABA Modulators; gamma-Aminobutyric Acid; Male; Norbornanes; Phosphinic Acids; Pyrimidines; Rats, Wistar; Receptors, GABA-B; Reflex, Startle | 2015 |
GABAB receptor upregulates fragile X mental retardation protein expression in neurons.
Topics: Animals; Baclofen; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Mice; Neurons; Receptors, GABA-B; Receptors, Somatomedin; Signal Transduction | 2015 |
Effects of Phenibut and Citrocard on Non-Competitive and Competitive Behavior during Provoked Aggression in Animals.
Topics: Agonistic Behavior; Animal Communication; Animals; Avoidance Learning; Baclofen; Competitive Behavior; Drug Evaluation, Preclinical; Electroshock; Escape Reaction; Fear; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Nootropic Agents; Pain; Rats; Tranquilizing Agents | 2015 |
New effects of GABAB receptor allosteric modulator rac-BHFF on ambient GABA, uptake/release, Em and synaptic vesicle acidification in nerve terminals.
Topics: Allosteric Regulation; Animals; Baclofen; Benzofurans; Cerebral Cortex; Dose-Response Relationship, Drug; Extracellular Space; GABA Agents; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Protons; Rats, Wistar; Receptors, GABA-B; Synaptic Vesicles; Synaptosomes; Tritium | 2015 |
GABAB receptors inhibit low-voltage activated and high-voltage activated Ca(2+) channels in sensory neurons via distinct mechanisms.
Topics: Animals; Baclofen; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, T-Type; Dithiothreitol; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Ganglia, Spinal; Guanosine Diphosphate; HEK293 Cells; Humans; Nociception; Pain; Patch-Clamp Techniques; Pertussis Toxin; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Sensory Receptor Cells; Signal Transduction; Thionucleotides | 2015 |
GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats.
Topics: Adipose Tissue, White; Afferent Pathways; Animals; Baclofen; gamma-Aminobutyric Acid; Isonicotinic Acids; Kidney; Male; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vigabatrin | 2015 |
Evaluation of the Percutaneous Absorption of Ketamine HCl, Gabapentin, Clonidine HCl, and Baclofen, in Compounded Transdermal Pain Formulations, Using the Franz Finite Dose Model.
Topics: Administration, Cutaneous; Aged; Amines; Baclofen; Clonidine; Cyclohexanecarboxylic Acids; Drug Compounding; Drug Evaluation, Preclinical; Gabapentin; gamma-Aminobutyric Acid; Humans; Ketamine; Male; Middle Aged; Organ Culture Techniques; Pain; Skin Absorption | 2016 |
GABA modulates baroreflex in the ventral tegmental area in rat.
Topics: Animals; Baclofen; Baroreflex; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Wistar; Ventral Tegmental Area | 2015 |
GABA-induced inactivation of dorsal midline thalamic subregions has distinct effects on emotional behaviors.
Topics: Animals; Baclofen; Emotions; Exploratory Behavior; GABA-A Receptor Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Male; Maze Learning; Microinjections; Midline Thalamic Nuclei; Motor Activity; Muscimol; Rats, Long-Evans | 2015 |
Prefrontal cortical GABAergic signaling and impaired behavioral flexibility in aged F344 rats.
Topics: Aging; Animals; Attention; Baclofen; Discrimination Learning; Executive Function; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Gene Expression; Male; Motor Activity; Prefrontal Cortex; Rats, Inbred F344; Reaction Time; Receptors, GABA-B; Space Perception; Visual Perception | 2017 |
THC:CBD Observational Study Data: Evolution of Resistant MS Spasticity and Associated Symptoms.
Topics: Adult; Amines; Baclofen; Calcium Channel Blockers; Cannabidiol; Cohort Studies; Cyclohexanecarboxylic Acids; Dronabinol; Drug Combinations; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Germany; Humans; Italy; Male; Medical Marijuana; Middle Aged; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Observational Studies as Topic; Oral Sprays; Plant Extracts; Pregabalin; Prospective Studies; Treatment Outcome | 2016 |
Comparison of Nootropic and Neuroprotective Features of Aryl-Substituted Analogs of Gamma-Aminobutyric Acid.
Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Baclofen; Cinnamates; Coma; Electroshock; gamma-Aminobutyric Acid; Male; Neuroprotective Agents; Nootropic Agents; Rats; Scopolamine | 2016 |
Unexpected Photo-instability of 2,6-Sulfonamide-Substituted BODIPYs and Its Application to Caged GABA.
Topics: Acetaldehyde; Animals; Baclofen; Basolateral Nuclear Complex; Boron Compounds; Formaldehyde; GABA Antagonists; gamma-Aminobutyric Acid; HeLa Cells; Humans; Light; Methylamines; Mice; Picrotoxin; Sulfonamides | 2016 |
GABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia.
Topics: Animals; Baclofen; Dementia, Vascular; Dentate Gyrus; Disease Models, Animal; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Memory Disorders; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-B; Spatial Learning | 2016 |
Interhemispheric regulation of the rat medial prefrontal cortical glutamate stress response: role of local GABA- and dopamine-sensitive mechanisms.
Topics: Animals; Baclofen; Benzazepines; Corpus Callosum; Dopamine; Dopamine Antagonists; Functional Laterality; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Interneurons; Male; Microdialysis; Neurons; Prefrontal Cortex; Raclopride; Rats; Rats, Long-Evans; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, GABA-B; Stress, Psychological | 2017 |
Protective roles of hepatic GABA signaling in acute liver injury of rats.
Topics: Animals; Baclofen; Chemical and Drug Induced Liver Injury; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Galactosamine; gamma-Aminobutyric Acid; Hep G2 Cells; Hepatocytes; Humans; Liver; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2017 |
Acupuncture reduces relapse to cocaine-seeking behavior via activation of GABA neurons in the ventral tegmental area.
Topics: Acupuncture; Animals; Baclofen; Behavior, Animal; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Electrophysiological Phenomena; GABA-B Receptor Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Locomotion; Microdialysis; Nucleus Accumbens; Rats; Ventral Tegmental Area | 2018 |
Validated Method for the Screening and Quantification of Baclofen, Gabapentin and Pregabalin in Human Post-Mortem Whole Blood Using Protein Precipitation and Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Amines; Autopsy; Baclofen; Chemical Precipitation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Pregabalin; Reproducibility of Results; Tandem Mass Spectrometry | 2017 |
Influence of leptin and GABA
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Chickens; Dose-Response Relationship, Drug; Female; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Leptin; Male; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques | 2017 |
GABAergic modulation of noradrenaline release caused by blood pressure changes in the rat median preoptic area.
Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Baclofen; Bicuculline; Blood Pressure; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Metaraminol; Microdialysis; Norepinephrine; Preoptic Area; Rats; Rats, Wistar | 2017 |
More Treatments on Deck for Alcohol Use Disorder.
Topics: Acamprosate; Alcohol Deterrents; Alcohol-Related Disorders; Amines; Baclofen; Cyclohexanecarboxylic Acids; Cytidine Diphosphate Choline; Disulfiram; Drug Repositioning; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Mifepristone; Naltrexone; National Institute on Alcohol Abuse and Alcoholism (U.S.); Off-Label Use; Patient Acceptance of Health Care; Taurine; Topiramate; United States; Varenicline | 2017 |
Dissociative Intoxication and Prolonged Withdrawal Associated With Phenibut: A Case Report.
Topics: Adult; Baclofen; Delirium; GABA Agonists; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawal Syndrome; Substance-Related Disorders | 2017 |
Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits.
Topics: Acoustic Stimulation; Animals; Auditory Perception; Autism Spectrum Disorder; Baclofen; Cadherins; Chromatography, High Pressure Liquid; Electrocorticography; Electrodes, Implanted; Evoked Potentials; Female; GABA-B Receptor Agonists; Gamma Rhythm; gamma-Aminobutyric Acid; Glutamine; Male; Mice, Transgenic; Protocadherins; Sex Characteristics; Theta Rhythm | 2017 |
Inhibitory Modulation of Orbitofrontal Cortex on Medial Prefrontal Cortex-Amygdala Information Flow.
Topics: Amygdala; Anesthesia; Animals; Baclofen; Bicuculline; Electric Stimulation; Emotions; Excitatory Amino Acid Agonists; Frontal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microelectrodes; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurons; Rats, Sprague-Dawley; Receptors, GABA | 2018 |
Baclofen and sleep apnoea syndrome: analysis of VigiBase, the WHO pharmacovigilance database.
Topics: Administration, Oral; Adverse Drug Reaction Reporting Systems; Alcoholism; Apnea; Baclofen; Databases, Pharmaceutical; Drug and Narcotic Control; Female; gamma-Aminobutyric Acid; Hospitalization; Humans; Injections, Spinal; Male; Muscle Spasticity; Nervous System Diseases; Pharmacovigilance; Sleep Apnea Syndromes | 2018 |
GABA-ergic neurotransmission in the nucleus of the solitary tract modulates cough in the cat.
Topics: Animals; Baclofen; Blood Pressure; Cats; Cough; Esophagus; gamma-Aminobutyric Acid; Heart Rate; Inhalation; Male; Muscimol; Neurotransmitter Agents; Receptors, GABA-B; Solitary Nucleus; Synaptic Transmission | 2018 |
GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys.
Topics: Animals; Axons; Baclofen; Caspases; Cell Survival; Enzyme Activation; gamma-Aminobutyric Acid; Lampreys; Larva; Morpholinos; Nerve Regeneration; Protein Subunits; Receptors, GABA; Signal Transduction; Spinal Cord Injuries | 2018 |
GABAergic mediation of hippocampal theta rhythm induced by stimulation of the vagal nerve.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Neurons; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Theta Rhythm; Vagus Nerve; Vagus Nerve Stimulation | 2019 |
The mechanism of chronic nicotine exposure and nicotine withdrawal on pain perception in an animal model.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Down-Regulation; Endorphins; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hyperalgesia; Male; Naloxone; Nicotine; Pain Perception; Pain Threshold; Rats; Receptors, Opioid, mu; Spinal Cord; Substance Withdrawal Syndrome; Time Factors; Up-Regulation | 2020 |
GABA consumption during early pregnancy impairs endometrial receptivity and embryo development in mice.
Topics: Administration, Oral; Animals; Baclofen; Cadherins; Dose-Response Relationship, Drug; Embryo Implantation; Embryonic Development; Endometrium; Female; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Homeobox A10 Proteins; Leukemia Inhibitory Factor; Mice; Pregnancy; Signal Transduction | 2020 |
Presynaptic GABA
Topics: Afferent Pathways; Animals; Axons; Baclofen; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Interneurons; Mice; Presynaptic Terminals; Rats; Receptors, GABA-B; Somatostatin | 2020 |
F-phenibut (β-(4-Fluorophenyl)-GABA), a potent GABA
Topics: Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; Female; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice, Inbred ICR; Potassium; Potassium Channels; Purkinje Cells; Receptors, GABA-B | 2020 |
Regulated expression and function of the GABA
Topics: Baclofen; Cell Line; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Pancreas; Receptors, G-Protein-Coupled; Receptors, GABA-B; Signal Transduction | 2020 |
Ivermectin Increases Random-Pattern Skin Flap Survival in Rats: The Novel Role of GABAergic System.
Topics: Animals; Baclofen; Bicuculline; Drug Repositioning; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Graft Survival; Humans; Ivermectin; Male; Models, Animal; Rats; Receptors, GABA-A; Receptors, GABA-B; Skin; Surgical Flaps | 2021 |
Endocannabinoids regulate cerebellar GABAergic transmission in a synapse type-dependent manner.
Topics: Animals; Baclofen; Benzoxazines; Cannabinoids; Cerebellum; Endocannabinoids; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Morpholines; Naphthalenes; Neural Inhibition; Presynaptic Terminals; Synaptic Transmission | 2021 |
Mice Expressing Regulators of G protein Signaling-insensitive Gαo Define Roles of
Topics: Analgesics, Opioid; Animals; Baclofen; Female; gamma-Aminobutyric Acid; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Inhibitory Postsynaptic Potentials; Male; Mice; Mice, Transgenic; Models, Animal; Presynaptic Terminals; Receptors, GABA-B; Receptors, Opioid, mu; RGS Proteins | 2021 |
Flexible versus Fixed Spatial Self-Ordered Response Sequencing: Effects of Inactivation and Neurochemical Modulation of Ventrolateral Prefrontal Cortex.
Topics: Animals; Antipsychotic Agents; Baclofen; Callithrix; Cognition Disorders; Dopamine; Dopamine D2 Receptor Antagonists; Fluorobenzenes; GABA Agonists; gamma-Aminobutyric Acid; Goals; Memory, Short-Term; Muscimol; Piperidines; Prefrontal Cortex; Psychomotor Performance; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Spatial Behavior; Sulpiride | 2021 |
Chronic Phenibut Use: Symptoms, Severe Withdrawal, and Recovery.
Topics: Adult; Baclofen; gamma-Aminobutyric Acid; Humans; Male; Substance Withdrawal Syndrome | 2022 |
[Effects of Governor Vessel electroacupuncture on chloridion homeostasis in the cortex of rats with limb spasm after cerebral ischemia-reperfusion].
Topics: Animals; Baclofen; Cerebral Cortex; Cerebral Infarction; Electroacupuncture; gamma-Aminobutyric Acid; Male; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury; Stroke | 2023 |