baclofen and dizocilpine maleate

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: Animals; Baclofen; Benzodiazepines; Caffeine; Diazepam; Dizocilpine Maleate; Flumazenil; Male; Mice; Muscimol; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic; Seizures

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Baclofen; Benzeneacetamides; Benzomorphans; Cerebral Ventricles; Convulsants; Dizocilpine Maleate; Injections, Intraventricular; Ketamine; Mice; Mice, Inbred Strains; Muscimol; Naloxone; Narcotic Antagonists; Narcotics; Pyrroles; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, kappa; Seizures; Stereoisomerism; Thiophenes

Topics: Animals; Baclofen; Diazepam; Digoxin; Dizocilpine Maleate; Female; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Muscimol; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Salts; Seizures

Topics: Anesthesia; Animals; Baclofen; Blood Pressure; Dizocilpine Maleate; Dose-Response Relationship, Drug; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; Pertussis Toxin; Pressoreceptors; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Urethane; Virulence Factors, Bordetella

Topics: Animals; Aspartic Acid; Baclofen; Bromocriptine; Catalepsy; Dibenzocycloheptenes; Dizocilpine Maleate; Drug Interactions; Haloperidol; Male; N-Methylaspartate; Nimodipine; Nitrendipine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Scopolamine

Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine

Topics: Animals; Baclofen; Cells, Cultured; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Neuronal Plasticity; Neurotransmitter Agents; Rats; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission

Topics: Animals; Baclofen; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Substantia Nigra

Topics: Animals; Baclofen; Cats; Decerebrate State; Dizocilpine Maleate; Evoked Potentials; Extracellular Space; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Medulla Oblongata; Nerve Net; Organophosphorus Compounds; Plethysmography; Receptors, GABA-A; Respiration

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Cerebral Ventricles; Dizocilpine Maleate; Glycosides; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Muscimol; Naloxone; Pain; Sincalide; Spinal Cord; Spirostans; Yohimbine

Topics: Adrenergic Uptake Inhibitors; Animals; Apomorphine; Baclofen; Benzazepines; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Excitatory Amino Acid Antagonists; GABA Agonists; Histocytochemistry; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Reserpine; Salicylamides; Stimulation, Chemical; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Atropine; Baclofen; Blood Pressure; Carbachol; Dizocilpine Maleate; Heart Rate; Male; Rats; Rats, Wistar; Receptors, GABA; Receptors, Glutamate; Receptors, Muscarinic; Spinal Cord

Topics: Animals; Baclofen; Biological Assay; Cerebral Hemorrhage; Cold Temperature; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-A Receptor Agonists; GABA-B Receptor Agonists; Hypertension; Male; Muscimol; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Suture Techniques

Topics: Animals; Avoidance Learning; Baclofen; Cyclic GMP; Dizocilpine Maleate; Functional Laterality; GABA Agonists; gamma-Aminobutyric Acid; Hippocampus; Male; Microinjections; Muscimol; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate

Topics: 3,4-Dihydroxyphenylacetic Acid; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Cycloleucine; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; GABA Agonists; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Microdialysis; Neuroprotective Agents; Norepinephrine; Nucleus Accumbens; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stress, Physiological

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Blotting, Northern; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; GAP-43 Protein; Gene Expression Regulation, Developmental; Glial Fibrillary Acidic Protein; Glutamic Acid; Immunohistochemistry; In Situ Hybridization; Microtubule-Associated Proteins; Muscimol; N-Methylaspartate; Neurons; Neuroprotective Agents; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger

Topics: Animals; Baclofen; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dizocilpine Maleate; GABA Agonists; GABA-B Receptor Agonists; Hyperalgesia; Indoles; Isoindoles; Male; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Pressure; Rats; Rats, Wistar; Sciatic Nerve; Spinal Cord; Substance P

Topics: Anesthetics, Intravenous; Animals; Baclofen; Diazepam; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Food; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Sodium Oxybate

Topics: Animals; Baclofen; Brain; Dizocilpine Maleate; GABA Modulators; Injections, Intraventricular; Interleukin-6; Male; Mice; Mice, Inbred ICR; Muscimol; Oxidopamine; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Stress, Physiological

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; In Vitro Techniques; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-B; Supraoptic Nucleus

Topics: Animals; Baclofen; Dizocilpine Maleate; Down-Regulation; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Muscimol; Neural Inhibition; Organ Culture Techniques; Rats; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Substance P

Topics: Animals; Baclofen; Cell Survival; Cells, Cultured; Cerebellum; Corpus Striatum; Dizocilpine Maleate; Drug Synergism; Embryo, Mammalian; Excitatory Amino Acid Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Kinetics; Mice; N-Methylaspartate; Neurons; Neurotoxins; Propionates; Receptors, GABA-B; Receptors, Metabotropic Glutamate

Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neural Inhibition; Neurons; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Strychnine; Synapses

Topics: Animals; Anterior Thalamic Nuclei; Baclofen; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Gyrus Cinguli; HSP70 Heat-Shock Proteins; Muscimol; Nerve Degeneration; Neural Pathways; Phytohemagglutinins; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia

Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Animals; Baclofen; Central Nervous System Stimulants; Dextroamphetamine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Neostriatum; Picrotoxin; Proactive Inhibition; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Stereotyped Behavior; Substantia Nigra

Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Growth Hormone; Growth Hormone-Releasing Hormone; Male; Muscimol; N-Methylaspartate; Neurosecretory Systems; Quinoxalines; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Sex Characteristics

Topics: Analgesics; Animals; Baclofen; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; Injections, Spinal; Male; Mice; N-Methylaspartate; Pain; Quinolines; Receptors, GABA-B; Spinal Cord

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Analgesics; Animals; Baclofen; Carbohydrate Sequence; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Injections, Spinal; Male; Methysergide; Mice; Mice, Inbred ICR; Molecular Sequence Data; Muscimol; Naloxone; Narcotic Antagonists; Pain Measurement; Plant Extracts; Platycodon; Receptors, Cholecystokinin; Receptors, N-Methyl-D-Aspartate; Saponins; Serotonin Antagonists; Sincalide; Tail; Triterpenes; Yohimbine

Topics: Acoustic Stimulation; Animals; Apomorphine; Baclofen; Dizocilpine Maleate; Male; Rats; Rats, Sprague-Dawley; Reflex, Startle

Topics: Afferent Pathways; Analysis of Variance; Anesthetics, Local; Animals; Axons; Baclofen; Calcium; Capsaicin; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Functional Laterality; GABA Agonists; Immunohistochemistry; In Vitro Techniques; Indoles; Isoindoles; Lidocaine; Microscopy, Confocal; Neurokinin-1 Receptor Antagonists; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Spinal Nerve Roots; Time Factors

Topics: Animals; Baclofen; Benzodiazepines; Diazepam; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Rats; Rats, Sprague-Dawley; Urinary Incontinence

Topics: Amyloid beta-Peptides; Analysis of Variance; Animals; Baclofen; Blotting, Western; Calcium; Calcium Channel Blockers; Caspase 3; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Female; GABA Agonists; Glutamic Acid; Muscimol; Neurons; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, GABA-A; Tetrazolium Salts; Thiazoles; Time Factors; Verapamil

Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Agonists; gamma-Aminobutyric Acid; Gene Expression Regulation, Enzymologic; Glutamate Decarboxylase; Male; Methylmalonic Acid; Muscimol; Rats; Rats, Wistar; Seizures

Topics: Analysis of Variance; Animals; Apoptosis; Baclofen; Brain Ischemia; Cerebral Infarction; Disease Models, Animal; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agents; In Situ Nick-End Labeling; Male; Muscimol; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Reperfusion; src-Family Kinases; Tyrosine

Topics: Animals; Baclofen; Central Nervous System Stimulants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Schedule; Excitatory Amino Acid Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Globus Pallidus; Immunohistochemistry; Male; Methamphetamine; Mice; Mice, Inbred ICR; Neural Inhibition; Neural Pathways; Pons; Proto-Oncogene Proteins c-fos; Receptors, GABA-B; Reticular Formation; Sensory Gating; Synaptic Transmission

Topics: Anesthetics, Intravenous; Animals; Area Under Curve; Ataxia; Baclofen; Catalepsy; Data Interpretation, Statistical; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Mice; Mice, Inbred C57BL; Muscle Relaxants, Central; Phencyclidine; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Sodium Oxybate

Topics: Animals; Baclofen; Blotting, Western; Brain Ischemia; Disks Large Homolog 4 Protein; Dizocilpine Maleate; GABA Agonists; Immunohistochemistry; Immunoprecipitation; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Muscimol; Neurons; Neuroprotective Agents; Nitric Oxide Synthase Type I; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, GABA

Topics: Animals; Antidepressive Agents; Arginine; Baclofen; Cyclic GMP; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Indazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase 5 Inhibitors; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Swimming

Topics: Animals; Baclofen; Bicuculline; Choice Behavior; Conditioning, Operant; Dizocilpine Maleate; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; Male; Memory, Short-Term; Muscimol; Prefrontal Cortex; Rats; Rats, Long-Evans; Receptors, GABA; Receptors, N-Methyl-D-Aspartate

Topics: Animals; Avoidance Learning; Baclofen; Basolateral Nuclear Complex; Behavior, Animal; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Memory Disorders; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

Topics: Animals; Baclofen; Biomarkers; Cell Differentiation; Cell Proliferation; Cell Survival; Dizocilpine Maleate; Doublecortin Protein; Embryo, Mammalian; Female; Levetiracetam; Male; Nerve Tissue Proteins; Neural Stem Cells; Neurogenesis; Neurons; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spheroids, Cellular

Topics: Animals; Baclofen; Disease Models, Animal; Dizocilpine Maleate; GABA-B Receptor Agonists; Perception; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia