baclofen and clozapine

baclofen has been researched along with clozapine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Liebman, J; Neale, R1
Bortolato, M; Castelli, MP; Fà, M; Frau, R; Gessa, GL; Marrosu, F; Mereu, G; Orrù, M; Piras, AP; Puligheddu, M; Tuveri, A1
Daskalakis, ZJ; George, TP1
Aston-Jones, G; McGlinchey, EM1
Bastiampillai, T; McKinnon, RA; Miners, JO; Nair, PC1

Reviews

3 review(s) available for baclofen and clozapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Clozapine, GABA(B), and the treatment of resistant schizophrenia.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:4

    Topics: Antipsychotic Agents; Baclofen; Clozapine; Drug Resistance; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Schizophrenia; Smoking; Tobacco Use Disorder; Transcranial Magnetic Stimulation

2009
Binding of clozapine to the GABA
    Molecular psychiatry, 2020, Volume: 25, Issue:9

    Topics: Baclofen; Clozapine; Molecular Docking Simulation; Receptors, GABA-B

2020

Other Studies

9 other study(ies) available for baclofen and clozapine

ArticleYear
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Neuroleptic-induced acute dyskinesias in squirrel monkeys: correlation with propensity to cause extrapyramidal side effects.
    Psychopharmacology, 1980, Volume: 68, Issue:1

    Topics: Animals; Antipsychotic Agents; Avoidance Learning; Baclofen; Basal Ganglia Diseases; Clozapine; Diazepam; Dyskinesia, Drug-Induced; Haloperidol; Haplorhini; Male; Saimiri

1980
Activation of GABA(B) receptors reverses spontaneous gating deficits in juvenile DBA/2J mice.
    Psychopharmacology, 2007, Volume: 194, Issue:3

    Topics: Animals; Antipsychotic Agents; Autoradiography; Baclofen; Brain; Clozapine; Disease Models, Animal; Dose-Response Relationship, Drug; GABA Agonists; Haloperidol; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neural Inhibition; Receptors, GABA-B; Reflex, Startle; Schizophrenia

2007
Dorsal Hippocampus Drives Context-Induced Cocaine Seeking via Inputs to Lateral Septum.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:5

    Topics: Animals; Baclofen; Behavior, Addictive; Clozapine; Cocaine; Cues; Drug-Seeking Behavior; Extinction, Psychological; Hippocampus; Locomotion; Male; Microinjections; Muscimol; Neuroanatomical Tract-Tracing Techniques; Oncogene Proteins v-fos; Rats; Self Administration; Septal Nuclei

2018