baclofen has been researched along with cgp 7930 in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (50.00) | 29.6817 |
| 2010's | 11 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Brown, KM; Colby, DA; Doerksen, RJ; Hockerman, GH; Roy, KK | 1 |
| Mascia, FM; Olianas, MC; Onali, P | 1 |
| Bettler, B; Bräuner-Osborne, H; Cryan, JF; Froestl, W; Kaupmann, K; Klebs, K; Mombereau, C; Mosbacher, J; Sansig, G; Schmutz, M; van der Putten, H; Waldmeier, P; Wellendorph, P | 1 |
| Carai, MA; Colombo, G; Froestl, W; Gessa, GL | 1 |
| Beart, PM; Carroll, FY; Chen, F; Cowen, MS; Crawford, D; Krstew, E; Lawrence, AJ; Liang, JH | 1 |
| Chen, Y; Menendez-Roche, N; Sher, E | 1 |
| Filip, M; Frankowska, M | 1 |
| Filip, M; Frankowska, M; Przegaliński, E | 1 |
| Cryan, JF; Jacobson, LH | 1 |
| Marino, V; Ong, J; Parker, DA; Prager, RH; Puspawati, NM | 1 |
| Brusberg, M; Larsson, H; Lindström, E; Martinez, V; Martinsson, R; Ravnefjord, A | 1 |
| Liu, J; Liu, Q; Pin, JP; Rondard, P; Tu, H; Xu, C; Zhang, W | 1 |
| Baizer, JS; Broussard, DM; Heskin-Sweezie, R; Titley, HK | 1 |
| Cheng, K; France, CP; Koek, W; Rice, KC | 2 |
| Badali, M; Khalafy, J; Marino, V; Ong, J; Parker, DA; Prager, RH; Rimaz, M; Sullivan, T | 1 |
| Advani, T; Burke, TF; Cheng, K; Hensler, JG; Koek, W; Rice, KC | 1 |
| Ebenezer, IS | 1 |
| Cheng, K; Koek, W; Rice, KC | 1 |
| Cedillo, LN; Miranda, F | 1 |
| Colombo, G; Contini, A; Leite-Morris, K; Lorrai, I; Maccioni, P | 1 |
1 review(s) available for baclofen and cgp 7930
| Article | Year |
|---|---|
Activation of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor by Agonists and Positive Allosteric Modulators.
Topics: Animals; GABA Agonists; GABA Antagonists; GABA Modulators; Humans; Molecular Conformation; Receptors, GABA-B; Structure-Activity Relationship | 2015 |
21 other study(ies) available for baclofen and cgp 7930
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Positive regulation of GABA(B) receptors dually coupled to cyclic AMP by the allosteric agent CGP7930.
Topics: Adenylyl Cyclases; Allosteric Regulation; Animals; Baclofen; Calmodulin; Colforsin; Corpus Striatum; Corticotropin-Releasing Hormone; Cyclic AMP; Cytoplasmic Granules; Drug Synergism; Frontal Lobe; gamma-Aminobutyric Acid; Gene Expression; Male; Olfactory Bulb; Phenols; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-B; Signal Transduction | 2003 |
Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.
Topics: 4-Butyrolactone; Adjuvants, Anesthesia; Animals; Anticonvulsants; Autoradiography; Baclofen; Behavior, Animal; Benzocycloheptenes; Binding, Competitive; Body Weight; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroencephalography; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Organophosphorus Compounds; Phenols; Radioligand Assay; Receptors, GABA-B; Sodium Oxybate; Time Factors | 2003 |
In vivo effectiveness of CGP7930, a positive allosteric modulator of the GABAB receptor.
Topics: Animals; Baclofen; Drug Synergism; GABA Agonists; GABA-B Receptor Antagonists; Hypnotics and Sedatives; Male; Mice; Mice, Inbred DBA; Morpholines; Phenols; Receptors, GABA-B; Sodium Oxybate; Stereoisomerism | 2004 |
The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Baclofen; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; GABA Modulators; Male; Motor Activity; Phenols; Rats; Self Administration; Time Factors | 2006 |
Differential modulation by the GABAB receptor allosteric potentiator 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)-phenol (CGP7930) of synaptic transmission in the rat hippocampal CA1 area.
Topics: Action Potentials; Allosteric Regulation; Animals; Baclofen; GABA Modulators; Hippocampus; In Vitro Techniques; Male; Phenols; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Synaptic Transmission | 2006 |
Effects of GABA(B) receptor agents on cocaine priming, discrete contextual cue and food induced relapses.
Topics: Animals; Baclofen; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Conditioning, Operant; Cues; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Feeding Behavior; GABA Agonists; GABA Antagonists; Injections, Intravenous; Male; Morpholines; Organophosphorus Compounds; Phenols; Rats; Rats, Wistar; Receptors, GABA-B; Reinforcement, Psychology; Secondary Prevention; Self Administration | 2007 |
Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination.
Topics: Animals; Baclofen; Cocaine; Discrimination Learning; GABA Modulators; Male; Morpholines; Motor Activity; Organophosphorus Compounds; Phenols; Rats; Rats, Wistar; Receptors, GABA-B; Self Administration | 2007 |
Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Behavior, Animal; Benzodiazepines; Body Temperature; Dose-Response Relationship, Drug; Drug Evaluation; Fever; GABA Agonists; Male; Maze Learning; Mice; Models, Animal; Motor Activity; Phenols; Physical Endurance; Psychomotor Performance; Rats | 2008 |
The CGP7930 analogue 2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol (BSPP) potentiates baclofen action at GABA(B) autoreceptors.
Topics: Animals; Baclofen; Drug Evaluation, Preclinical; Drug Synergism; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Morpholines; Neocortex; Organ Culture Techniques; Phenols; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spiro Compounds; Tritium | 2008 |
The GABA(B) receptor agonist, baclofen, and the positive allosteric modulator, CGP7930, inhibit visceral pain-related responses to colorectal distension in rats.
Topics: Abdominal Pain; Animals; Baclofen; Blood Pressure; Colon; Compliance; Dilatation, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Female; GABA Agonists; Heart Rate; Pain Measurement; Phenols; Physical Stimulation; Rats; Rats, Sprague-Dawley | 2009 |
GABAB receptor activation protects neurons from apoptosis via IGF-1 receptor transactivation.
Topics: Animals; Animals, Newborn; Apoptosis; Baclofen; Bicuculline; Calcium; Caspase 3; Cells, Cultured; Cerebellum; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; In Situ Nick-End Labeling; Mice; Mice, Inbred Strains; Models, Biological; Morpholines; Neurons; Oncogene Protein v-akt; Pertussis Toxin; Phenols; Phosphinic Acids; Phosphorylation; Potassium; Pyridines; Receptor, IGF Type 1; Receptors, GABA-A; RNA Interference; Signal Transduction; Transcriptional Activation | 2010 |
Type B GABA receptors contribute to the restoration of balance during vestibular compensation in mice.
Topics: Adaptation, Physiological; Animals; Ataxia; Baclofen; Benzoates; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Lameness, Animal; Male; Mice; Mice, Inbred C57BL; Phenols; Phosphinic Acids; Postural Balance; Receptors, GABA-B; Recovery of Function; Reflex; Vestibular Nucleus, Lateral; Vestibule, Labyrinth | 2010 |
GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.
Topics: Animals; Baclofen; Benzofurans; Body Temperature; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Hypothermia; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organophosphorus Compounds; Phenols; Sodium Oxybate | 2010 |
Pharmacological actions of oximino-propofol analogues at GABA(B) autoreceptors.
Topics: Animals; Autoreceptors; Baclofen; Electric Stimulation; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Morpholines; Neocortex; Oximes; Phenols; Propofol; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Tritium | 2011 |
GABAB receptor-positive modulators: brain region-dependent effects.
Topics: Animals; Autoradiography; Baclofen; Benzofurans; Brain; Brain Chemistry; GABA Agonists; GABA Modulators; Guanosine 5'-O-(3-Thiotriphosphate); Image Processing, Computer-Assisted; In Vitro Techniques; Mice; Mice, Inbred C57BL; Phenols; Receptors, GABA-B; Sodium Oxybate | 2012 |
Effects of the GABAB receptor-positive modulators CGP7930 and rac-BHFF in baclofen- and γ-hydroxybutyrate-discriminating pigeons.
Topics: Animals; Baclofen; Benzofurans; Columbidae; Conditioning, Operant; Discrimination, Psychological; GABA Antagonists; GABA-B Receptor Agonists; Phenols; Phosphinic Acids; Receptors, GABA-B; Sodium Oxybate | 2012 |
Effects of intraperitoneal administration of the GABAB receptor positive allosteric modulator 2,6-di tert-butyl-4-(2-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) on food intake in non-deprived rats.
Topics: Allosteric Regulation; Animals; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; Eating; GABA-B Receptor Agonists; Hyperphagia; Injections, Intraperitoneal; Male; Phenols; Rats; Rats, Wistar; Receptors, GABA-B | 2012 |
Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse.
Topics: Animals; Baclofen; Benzodiazepines; Benzofurans; Cocaine; Columbidae; Diazepam; Discrimination, Psychological; Ethanol; GABA-B Receptor Agonists; Illicit Drugs; Nicotine; Organophosphorus Compounds; Phenols; Sodium Oxybate | 2013 |
Effects of co-administration of the GABAB receptor agonist baclofen and a positive allosteric modulator of the GABAB receptor, CGP7930, on the development and expression of amphetamine-induced locomotor sensitization in rats.
Topics: Amphetamine; Animals; Baclofen; Behavior, Animal; Brain; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; GABA-B Receptor Agonists; Male; Motor Activity; Phenols; Rats; Rats, Wistar; Receptors, GABA-B | 2013 |
Microinjection of baclofen and CGP7930 into the ventral tegmental area suppresses alcohol self-administration in alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Baclofen; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; GABA-B Receptor Agonists; Genetic Predisposition to Disease; Male; Microinjections; Motor Activity; Phenols; Rats; Self Administration; Ventral Tegmental Area | 2018 |