baclofen has been researched along with 4-hydroxybutyric acid in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bay, T; Bundgaard, C; Clausen, RP; Frølund, B; Kehler, J; Marek, A; Pedersen, MH; Vogensen, SB; Wellendorph, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Müller, EE; Rigamonti, AE | 1 |
| Coiro, V; Vescovi, PP | 1 |
| Cossu, G; Deiana, S; Fattore, L; Fratta, W; Martellotta, MC | 1 |
| Brunetti, G; Carai, MA; Cignarella, G; Colombo, G; Gessa, GL; Mastinu, S; Melis, S; Minardi, G; Pistuddi, AM; Serra, S; Solinas, C; Vacca, G | 1 |
| Bortolato, M; Carta, G; Gessa, GL; Nava, F | 1 |
| Affricano, D; Barbaccia, ML; Carai, MA; Colombo, G; Gessa, GL; Melis, S; Purdy, RH; Vacca, G | 1 |
| Cruz, HG; Ivanova, T; Lunn, ML; Lüscher, C; Slesinger, PA; Stoffel, M | 1 |
| Odagaki, Y; Yamauchi, T | 1 |
| Carai, MA; Colombo, G; Froestl, W; Gessa, GL; Serra, S; Vacca, G | 1 |
| Carai, MA; Colombo, G; Gessa, GL; Lobina, C | 1 |
| Cignarella, G; Gessa, GL; Melis, M; Muntoni, AL; Perra, S; Pillolla, G; Pistis, M | 1 |
| Bernardi, M; Caputo, F; Francini, S; Stoppo, M; Vignoli, T | 1 |
| Amato, L; Davoli, M; Minozzi, S | 1 |
| Chen, L; Crunelli, V; Emri, Z; Errington, AC; Gould, T; Parri, HR; Pirttimaki, T | 1 |
| Greene, S; Kailainathan, R; Koutsogiannis, Z; Wong, A | 1 |
| Diouf, M; González-Marín, MC; Jeanblanc, J; Lebourgeois, S; Naassila, M | 1 |
2 review(s) available for baclofen and 4-hydroxybutyric acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome.
Topics: Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Baclofen; Benzodiazepines; Ethanol; Humans; Hydroxybutyrates; Nitrous Oxide; Substance Withdrawal Syndrome | 2011 |
16 other study(ies) available for baclofen and 4-hydroxybutyric acid
| Article | Year |
|---|---|
New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.
Topics: Animals; Benzocycloheptenes; Binding Sites; Binding, Competitive; Brain; Carboxylic Acids; Cell Line; Central Nervous System; Cyclopentanes; Drug Stability; gamma-Aminobutyric Acid; Hydroxybutyrates; Kinetics; Ligands; Male; Models, Chemical; Molecular Structure; Radioligand Assay; Rats; Rats, Sprague-Dawley; Synaptic Membranes; Tritium | 2013 |
Gamma-hydroxybutyric acid and growth hormone secretion studies in rats and dogs.
Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Baclofen; Clonidine; Dogs; Female; GABA Agonists; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hydroxybutyrates; Male; Oligopeptides; Pituitary Gland; Prolactin; Rats | 2000 |
Different control of GH secretion by gamma-amino- and gamma-hydroxy-butyric acid in 4-year abstinent alcoholics.
Topics: Adult; Alcoholism; Baclofen; Biomarkers; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hydroxybutyrates; Male; Statistics, Nonparametric; Temperance; Valproic Acid | 2001 |
Baclofen antagonises intravenous self-administration of gamma-hydroxybutyric acid in mice.
Topics: Animals; Baclofen; Behavior, Addictive; GABA Agonists; Hydroxybutyrates; Injections, Intravenous; Male; Mice; Receptors, GABA-B; Reinforcement, Psychology; Self Administration | 2001 |
Role of GABA(B) receptors in the sedative/hypnotic effect of gamma-hydroxybutyric acid.
Topics: Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Hydroxybutyrates; Hypnotics and Sedatives; Male; Mice; Mice, Inbred DBA; Morpholines; Receptors, GABA-B; Reflex | 2001 |
gamma-Hydroxybutyric acid and baclofen decrease extracellular acetylcholine levels in the hippocampus via GABA(B) receptors.
Topics: Acetylcholine; Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Dose-Response Relationship, Drug; Extracellular Space; GABA Agonists; GABA Antagonists; Hippocampus; Hydroxybutyrates; Male; Morpholines; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Time Factors | 2001 |
GABA(B) receptor-mediated increase of neurosteroids by gamma-hydroxybutyric acid.
Topics: Animals; Baclofen; Cerebral Cortex; Desoxycorticosterone; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Hippocampus; Hydroxybutyrates; Male; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-B | 2002 |
Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system.
Topics: Animals; Baclofen; Dopamine; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Agonists; GABA-B Receptor Agonists; Humans; Hydroxybutyrates; Mice; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Ventral Tegmental Area | 2004 |
Gamma-hydroxybutyric acid, unlike gamma-aminobutyric acid, does not stimulate Gi/Go proteins in rat brain membranes.
Topics: Animals; Baclofen; Brain; Cell Membrane; GABA Agonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hydroxybutyrates; Male; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface | 2004 |
Suppression of GABA(B) receptor function in vivo by disulfide reducing agent, DL-dithiothreitol (DTT).
Topics: Animals; Baclofen; Conditioning, Operant; Discrimination Learning; Dithiothreitol; Drug Interactions; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Hydroxybutyrates; Male; Mice; Mice, Inbred DBA; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Long-Evans; Reflex | 2004 |
Different sensitivity to the motor incoordinating effects of gamma-hydroxybutyric acid (GHB) and baclofen in GHB-sensitive and GHB-resistant rats.
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Female; GABA Agonists; Hydroxybutyrates; Hypnotics and Sedatives; Motor Activity; Psychomotor Performance; Rats; Rotarod Performance Test | 2005 |
Gamma-hydroxybutyric acid (GHB) and the mesoaccumbens reward circuit: evidence for GABA(B) receptor-mediated effects.
Topics: Action Potentials; Animals; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; Hydroxybutyrates; Male; Nerve Net; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Reward | 2005 |
GABAergic medications for treating alcohol dependence.
Topics: Alcoholism; Baclofen; Drug Therapy, Combination; GABA Agonists; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Receptors, GABA-B; Substance Withdrawal Syndrome; Temperance | 2007 |
GABA(B) receptor-mediated activation of astrocytes by gamma-hydroxybutyric acid.
Topics: Animals; Astrocytes; Baclofen; Dose-Response Relationship, Drug; Epilepsy; Female; Hydroxybutyrates; Male; Mice; Mice, Knockout; Microscopy, Fluorescence; Rats; Rats, Wistar; Receptors, GABA-B; Reward; Ventral Tegmental Area; Ventral Thalamic Nuclei | 2014 |
Recognition of gamma-hydroxybutyric acid withdrawal: Rapid progression and prolonged symptomatology.
Topics: Adult; Anti-Bacterial Agents; Australia; Baclofen; Benzodiazepines; Diazepam; Humans; Hydroxybutyrates; Male; Penicillanic Acid; Phenobarbital; Piperacillin; Pneumonia; Psychomotor Agitation; Substance Withdrawal Syndrome; Sweating; Tazobactam; Tremor | 2017 |
Evaluation of alcohol use disorders pharmacotherapies in a new preclinical model of binge drinking.
Topics: Acamprosate; Animals; Baclofen; Binge Drinking; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Extinction, Psychological; Hydroxybutyrates; Male; Motivation; Naltrexone; Rats; Self Administration | 2018 |