Page last updated: 2024-08-24

baccatin iii and paclitaxel

baccatin iii has been researched along with paclitaxel in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	23 (28.40)	18.2507
2000's	30 (37.04)	29.6817
2010's	23 (28.40)	24.3611
2020's	5 (6.17)	2.80

Authors

Authors	Studies
Burke, CT; Cheruvallath, ZS; Georg, GI; Himes, RH; Mejillano, MR	1
Hosoyama, H; Kobayashi, J; Shigemori, H; Sudo, Y; Tsuruo, T; Wang, XX	1
Abe, M; Ando, M; Bai, J; Hasegawa, T; Hirose, K; Kawakami, J; Kikuchi, M; Matsubara, J; Sakai, J; Tomida, A; Tsuruo, T; Wang, J; Zhang, S	1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P	1
Bu, XZ; Chen, Y; Guo, YQ; Jin, J; Qiu, J; Sun, ZH; Tang, GH; Yin, S; Zhu, CG	1
Alvarado, AB; Brobst, SW; Hoover, AJ; Jech, K; Masters, S; Snader, KM; Wheeler, NC	1
Chang, CJ; Cooks, RG; Hoke, SH; Li, XH; Wood, JM	1
Chen, WM; Fang, QC; Liu, X; Rao, C; Zhang, PL	1
Alvarado, B; Bignami, GS; Byrnes, JB; Grothaus, PG; Harada, KE; McGuire, MT; O'Malley, S; Raybould, TJ; Waller, DF	1
Alvarado, B; Chang, CJ; Cooks, RG; Hoke, SH; Kelly, RC; McGuire, MT; Qualls, SJ; Snader, KM	1
Alvarado, AB; Chan, KC; Issaq, HJ; McGuire, MT; Muschik, GM; Snader, KM	1
Bignami, GS; Byrnes, JB; Grothaus, PG; Lazo, CB; Raybould, TJ	1
Kingston, DG; Neidigh, KA; Samaranayake, G	1
Cordell, GA; Kingston, DG; Neidigh, KA; Pengsuparp, T; Pezzuto, JM	1
Ewald, D; Hacker, C; Hornbogen, T; Kammer, B; Weckwerth, W; Zocher, R	1
Eugster, C; Forni, G; Rivara, G; Vai, S	1
Tabancay, AP; Wang, CJ; Woo, DD	1
Hara, Y; Higashi, Y; Tabata, H; Yukimune, Y	1
Gordon, M	1
Croteau, RB; Gibson, DM; Ketchum, RE; Shuler, ML	1
Barthol, A; Croteau, R; Gatfield, D; Goleniowski, M; Hezari, M; Ketchum, RE; Walker, K	1
Fan, W	1
Glowniak, K; Mroczek, T; Zobel, AM	1
Baloglu, E; Kingston, DG	1
Fan, W; Johnson, KR; Miller, MC; Willingham, MC	1
Hara, Y; Nomura, E; Seto, H; Yoshida, S; Yukimune, Y	1
Abela, BA; Mulchandani, A; Sheikh, SH	1
Chen, JR; Frechét, JJ; Peters, EC; Svec, F; Zare, RN	1
Bane, S; Barron, DM; Chatterjee, SK; Vos, S	1
Andreu, JM; Barasoain, I	1
Duchateau, J; Jaziri, M; Vanhaelen, M; Vanhaelen-Fastré, R	1
Alvinerie, P; Cresteil, T; Dubois, J; Gueritte, F; Monsarrat, B; Sonnier, M	1
Chen, Y; Hu, Q; Wu, Y; Zhu, W	1
Alfermann, AW; Cusidó, RM; Garden, H; Navia-Osorio, A; Palazón, J; Piñol, MT	1
Ahn, YM; Georg, GI; Vander Velde, DG	1
Braga, SF; Galvão, DS	1
Bonfill, M; Cusidó, RM; Morales, C; Palazón, J; Piñol, MT	1
Appendino, G; Ballero, M; Loi, MC; Poli, F; van Beek, TA; van de Haar, C; van Rozendaal, EL	1
Dolfinger, R; Locke, DC	1
Baldelli, E; Battaglia, A; Bombardelli, E; Carenzi, G; Fontana, G; Gambini, A; Gelmi, ML; Guerrini, A; Pocar, D	1
Almqvist, F; Berg, U; Frejd, T; Manner, S; Thornqvist, V; Wallin, M	1
Cui, H; Ge, F	1
Bentebibel, S; Bonfill, M; Cusidó, RM; Eibl, R; Moyano, E; Palazón, J; Piñol, MT	1
Bollon, AP; Croteau, RB; Dejong, JM; Jennewein, S; Liu, Y; Long, RM; Williams, D	1
Armirotti, A; Benatti, U; Damonte, G; Miele, M	1
Yu, LJ; Zhao, CF	1
Audus, KL; Datta, A; Desino, K; Dutta, D; Georg, GI; Himes, RH; Huff, JK; Rice, A; Seelig, A; Spletstoser, JT; Turunen, BJ	1
Loncaric, C; Merriweather, E; Walker, KD	1
Hanson, RL; Parker, WL; Patel, RN	1
Fu, Y; Li, Q; Li, S; Schwarz, G; Sun, R; Zu, Y	1
Doi, T; Fuse, S; Miyamoto, S; Nakai, K; Sasuga, D; Takahashi, T	1
Chen, X; Dai, J; Li, J; Zhu, P	1
Grant, DM; Harper, JK; Heider, EM	1
Dukor, RK; Izumi, H; Nafie, LA; Ogata, A	1
Pang, HH; Sun, JY; Yang, FJ; Zhang, XK; Zu, YG	1
Barradas-Dermitz, DM; Hayward-Jones, PM; Mata-Rosas, M; Palmeros-Sánchez, B; Platas-Barradas, OB; Velásquez-Toledo, RF	1
Hong, JT; Im, SA; Kim, K; Kim, KH; Kim, Y; Lee, CK; Lee, MK; Lee, YH; Lee, YR; Song, S	1
Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J	1
Abdolmaleki, P; Ghanati, F; Hajnoruzi, A; Mokhtari-Dizaji, M; Rezaei, A; Safari, M	1
Guifang, X; Li, M; Xiuren, Z; Zaiyou, J	1
Guo, LQ; Han, F; Kang, LZ; Lin, JF; Ye, ZW; Zeng, XL	1
Hong, JT; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Park, CS; Song, S; Whang, BY	1
Huang, RG; Liang, ZK; Xie, ZS; Xu, XJ	1
Bonfill, M; Cusido, RM; Eibl, R; Gallego, A; Imseng, N; Moyano, E; Palazon, J	1
Bai, X; Gou, X; Hou, X; Huang, M; Jin, J; Li, D; Liu, B; Zhong, G	1
Li, YJ; Li, ZW; Wang, L	1
Bonfill, M; Cusido, RM; Moyano, E; Osuna, L; Palazon, J; Ramirez-Estrada, K; Tapia, N	1
Cui, YM; Li, QF; Lin, HX; Xu, PP	1
Muchiri, R; Walker, KD	1
Kasaei, A; Mahjoubi, F; Mobini-Dehkordi, M; Saffar, B	1
Thornburg, CK; Walker, KD; Walter, T	1
Guo, LQ; Huang, JJ; Lin, JF; Lin, SL; Ouyang, PL; Wei, JB; Wei, T; Wu, GP	1
Guo, LQ; Huang, JJ; Jiang, BH; Lin, JF; Wei, T; You, LF; Zheng, QW	1
Gao, JM; Li, J; Shi, YQ; Zhang, CY; Zhang, QM	1
Jayabaskaran, C; Sah, B; Subban, K	1
Guo, LQ; Jiang, BH; Lin, JF; Wei, T; You, LF; Zheng, QW	1
Nawarathne, IN; Sullivan, SA; Walker, KD	1
Guo, LQ; Han, PY; Han, WF; Huang, JJ; Lin, JF; Wei, T; Ye, AQ	1
Ahmad, S; Amin, S; Mir, SR; Nurullah, M; Panda, BP; Usmani, Z	1
Altmann, KH; Bargsten, K; Díaz, JF; Estevez-Gallego, J; Fang, WS; Gago, F; Gaillard, N; Josa-Prado, F; Kamimura, S; Li, S; Lucena-Agell, D; Ma, Y; Mühlethaler, T; Oliva, MA; Prota, AE; Steinmetz, MO	1
Alseekh, S; Christmann, M; Fang, H; Fernie, AR; Molloy, J; Perez de Souza, L; Scossa, F; Wiese, L; Zhang, Y	1

Other Studies

81 other study(ies) available for baccatin iii and paclitaxel

Article	Year
Synthesis of biologically active taxol analogues with modified phenylisoserine side chains. Journal of medicinal chemistry, 1992, Oct-30, Volume: 35, Issue:22 Topics: Animals; Antineoplastic Agents; Cattle; Drug Screening Assays, Antitumor; In Vitro Techniques; Melanoma, Experimental; Microtubules; Molecular Conformation; Paclitaxel; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured	1992
Modulation of multidrug resistance by taxuspine C and other taxoids from Japanese yew. Bioorganic & medicinal chemistry letters, 1998, Jun-16, Volume: 8, Issue:12 Topics: Animals; Bridged-Ring Compounds; Carcinoma, Squamous Cell; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Leukemia L1210; Leukemia P388; Mice; Phenylpropionates; Taxoids; Trees; Tumor Cells, Cultured; Vincristine	1998
Structure-activity relationships of some taxoids as multidrug resistance modulator. Bioorganic & medicinal chemistry letters, 2007, Feb-15, Volume: 17, Issue:4 Topics: Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Structure-Activity Relationship; Taxoids; Taxus	2007
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22 Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship	2012
Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. mairei. Bioorganic & medicinal chemistry letters, 2015, Mar-15, Volume: 25, Issue:6 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Mice; Molecular Conformation; NIH 3T3 Cells; Paclitaxel; Plant Bark; Structure-Activity Relationship; Taxoids; Taxus	2015
Effects of genetic, epigenetic, and environmental factors on taxol content in Taxus brevifolia and related species. Journal of natural products, 1992, Volume: 55, Issue:4 Topics: Alkaloids; Analysis of Variance; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Paclitaxel; Plants, Medicinal; Seasons; Taxoids; Trees	1992
Rapid screening for taxanes by tandem mass spectrometry. Analytical chemistry, 1992, Oct-15, Volume: 64, Issue:20 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Mass Spectrometry; Paclitaxel; Plants; Taxoids	1992
[Application of high speed countercurrent chromatography for the isolation of natural products--preparative isolation of taxane-diterpenoids and diterpene alkaloids]. Yao xue xue bao = Acta pharmaceutica Sinica, 1991, Volume: 26, Issue:7 Topics: Alkaloids; Chromatography; Drugs, Chinese Herbal; Paclitaxel; Taxoids	1991
Taxane-specific monoclonal antibodies: measurement of taxol, baccatin III, and "total taxanes" in Taxus brevifolia extracts by enzyme immunoassay. Journal of natural products, 1995, Volume: 58, Issue:7 Topics: Alkaloids; Animals; Antibodies, Monoclonal; Antibody Specificity; Bridged-Ring Compounds; Cross Reactions; Drugs, Chinese Herbal; Female; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Paclitaxel; Plant Extracts; Plant Leaves; Plants, Medicinal; Taxoids	1995
Determination of taxanes in Taxus brevifolia extracts by tandem mass spectrometry and high-performance liquid chromatography. Journal of natural products, 1994, Volume: 57, Issue:2 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Mass Spectrometry; Paclitaxel; Plant Extracts; Plants, Medicinal; Taxoids	1994
High-performance liquid chromatography and micellar electrokinetic chromatography of taxol and related taxanes from bark and needle extracts of Taxus species. Journal of chromatography. B, Biomedical applications, 1994, Jul-15, Volume: 657, Issue:2 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drugs, Chinese Herbal; Micelles; Paclitaxel; Spectrophotometry, Ultraviolet; Taxoids; Trees	1994
An enzyme immunoassay for the determination of taxol and taxanes in Taxus sp. tissues and human plasma. Journal of immunological methods, 1993, Jan-14, Volume: 158, Issue:1 Topics: Alkaloids; Animals; Antibody Specificity; Female; Hemocyanins; Humans; Immunoenzyme Techniques; Paclitaxel; Rabbits; Taxoids; Trees; Triterpenes	1993
Modified taxols, 8. Deacylation and reacylation of baccatin III. Journal of natural products, 1993, Volume: 56, Issue:6 Topics: Acylation; Alkaloids; Dealkylation; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Paclitaxel; Taxoids	1993
Evaluation of the cytotoxic mechanism mediated by baccatin III, the synthetic precursor of taxol. Chemico-biological interactions, 1996, Aug-14, Volume: 101, Issue:2 Topics: Alkaloids; Animals; Antineoplastic Agents; Binding Sites; Cell Cycle; Colchicine; Humans; Mice; Microtubules; Paclitaxel; Podophyllotoxin; Polymers; Protein Binding; Taxoids; Tubulin; Tumor Cells, Cultured; Vinblastine	1996
Biosynthesis of taxol: enzymatic acetylation of 10-deacetylbaccatin-III to baccatin-III in crude extracts from roots of Taxus baccata. Biochemical and biophysical research communications, 1996, Dec-04, Volume: 229, Issue:1 Topics: Acetylation; Alkaloids; Antineoplastic Agents, Phytogenic; Cell-Free System; Chromatography, High Pressure Liquid; Paclitaxel; Plant Roots; Plants, Medicinal; Taxoids; Triterpenes	1996
Marigenol-concentrates comprising Taxol and/or Taxan esters as active substances. Panminerva medica, 1996, Volume: 38, Issue:4 Topics: Alkaloids; Antineoplastic Agents; Antiviral Agents; Chemistry, Pharmaceutical; Emulsions; Humans; Paclitaxel; Pharmaceutical Vehicles; Phytosterols; Solubility; Taxoids	1996
Microtubule active taxanes inhibit polycystic kidney disease progression in cpk mice. Kidney international, 1997, Volume: 51, Issue:5 Topics: Alkaloids; Animals; Kidney; Mice; Mice, Inbred C57BL; Microtubules; Paclitaxel; Polycystic Kidney Diseases; Structure-Activity Relationship; Taxoids	1997
Methyl jasmonate-induced overproduction of paclitaxel and baccatin III in Taxus cell suspension cultures. Nature biotechnology, 1996, Volume: 14, Issue:9 Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Biotechnology; Cells, Cultured; Cyclopentanes; Oxylipins; Paclitaxel; Plant Growth Regulators; Plants, Medicinal; Species Specificity; Taxoids	1996
Taxol supply problem? What problem? Nature biotechnology, 1996, Volume: 14, Issue:13 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Biotechnology; Cell Culture Techniques; Drugs, Chinese Herbal; Paclitaxel; Taxoids	1996
The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate. Biotechnology and bioengineering, 1999, Jan-05, Volume: 62, Issue:1 Topics: Acetates; Alkaloids; Biotechnology; Cell Division; Cells, Cultured; Cyclopentanes; Kinetics; Oxylipins; Paclitaxel; Plant Growth Regulators; Plants, Medicinal; Taxoids	1999
Partial purification and characterization of acetyl coenzyme A: taxa-4(20),11(12)-dien-5alpha-ol O-acetyl transferase that catalyzes the first acylation step of taxol biosynthesis. Archives of biochemistry and biophysics, 1999, Apr-15, Volume: 364, Issue:2 Topics: Acetyltransferases; Acylation; Alkaloids; Kinetics; Paclitaxel; Plants, Medicinal; Substrate Specificity; Taxoids; Time Factors; Triterpenes	1999
Possible mechanisms of paclitaxel-induced apoptosis. Biochemical pharmacology, 1999, Jun-01, Volume: 57, Issue:11 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Drug Interactions; G2 Phase; Glucocorticoids; Humans; Mitosis; Paclitaxel; Taxoids; Tumor Cells, Cultured	1999
Seasonal changes in the concentrations of four taxoids in Taxus baccata L. during the autumn-spring period. Phytomedicine : international journal of phytotherapy and phytopharmacology, 1999, Volume: 6, Issue:2 Topics: Alkaloids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Molecular Structure; Paclitaxel; Seasons; Taxoids; Trees; Triterpenes	1999
A new semisynthesis of paclitaxel from baccatin III. Journal of natural products, 1999, Volume: 62, Issue:7 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Drugs, Chinese Herbal; Indicators and Reagents; Magnetic Resonance Spectroscopy; Paclitaxel; Spectrometry, Mass, Fast Atom Bombardment; Taxoids	1999
Apoptotic cell death induced by baccatin III, a precursor of paclitaxel, may occur without G(2)/M arrest. Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:6 Topics: Alkaloids; Apoptosis; Breast Neoplasms; Cell Cycle; DNA Fragmentation; DNA, Neoplasm; Drugs, Chinese Herbal; Female; G2 Phase; Humans; KB Cells; Microtubules; Mitosis; Nucleosomes; Paclitaxel; Prohibitins; Taxoids; Tumor Cells, Cultured	1999
The configuration of methyl jasmonate affects paclitaxel and baccatin III production in Taxus cells. Phytochemistry, 2000, Volume: 54, Issue:1 Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Cell Division; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyclopentanes; Oxylipins; Paclitaxel; Plants, Medicinal; Stereoisomerism; Taxoids; Taxus	2000
Development of a fluorescence immunoassay for measurement of paclitaxel in human plasma. Analytical biochemistry, 2000, Jul-15, Volume: 283, Issue:1 Topics: Alkaloids; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Immunoassay; Immunoglobulin G; Paclitaxel; Reproducibility of Results; Rhodamines; Spectrometry, Fluorescence; Staphylococcal Protein A; Taxoids; Time Factors; Triterpenes	2000
Semipreparative capillary electrochromatography. Analytical chemistry, 2001, May-01, Volume: 73, Issue:9 Topics: Alkaloids; Chromatography, High Pressure Liquid; Electrochemistry; Electrophoresis, Capillary; Methacrylates; Paclitaxel; Polymers; Silicon Dioxide; Taxoids	2001
Baccatin III induces assembly of purified tubulin into long microtubules. Biochemistry, 2001, Jun-12, Volume: 40, Issue:23 Topics: Alkaloids; Animals; Cattle; Dose-Response Relationship, Drug; Guanosine Triphosphate; Inhibitory Concentration 50; Microscopy, Electron; Microtubules; Paclitaxel; Polymers; Taxoids; Tubulin	2001
The interaction of baccatin III with the taxol binding site of microtubules determined by a homogeneous assay with fluorescent taxoid. Biochemistry, 2001, Oct-09, Volume: 40, Issue:40 Topics: Alkaloids; Animals; Antineoplastic Agents, Phytogenic; Cattle; Chromatography, High Pressure Liquid; Flow Cytometry; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Microtubules; Paclitaxel; Spectrometry, Fluorescence; Structure-Activity Relationship; Taxoids; U937 Cells	2001
Taxanes in Taxus baccata pollen: cardiotoxicity and/or allergenicity? Planta medica, 2002, Volume: 68, Issue:1 Topics: Alkaloids; Animals; Antibodies, Anti-Idiotypic; Antineoplastic Agents, Phytogenic; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Humans; Hypersensitivity; Immunoglobulin G; Male; Mice; Paclitaxel; Plant Extracts; Plant Leaves; Pollen; Taxoids; Taxus; Toxicity Tests, Acute	2002
Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:4 Topics: Alkaloids; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; COS Cells; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Docetaxel; Humans; Hydroxylation; Microsomes, Liver; Mixed Function Oxygenases; Paclitaxel; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Structure-Activity Relationship; Substrate Specificity; Taxoids; Triterpenes	2002
[Effects of phenylalanine, sucrose and mannitol on the growth and production of taxol, baccatin III and 10-deacetylbaccatin III in suspension cells of Taxus media]. Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:2 Topics: Alkaloids; Cell Division; Cells, Cultured; Mannitol; Paclitaxel; Phenylalanine; Sucrose; Taxoids; Taxus; Triterpenes	1998
Production of paclitaxel and baccatin III in a 20-L airlift bioreactor by a cell suspension of Taxus wallichiana. Planta medica, 2002, Volume: 68, Issue:4 Topics: Air; Alkaloids; Biomass; Bioreactors; Cell Division; Cells, Cultured; Hydrogen-Ion Concentration; Paclitaxel; Taxoids; Taxus	2002
Synthetic studies with 13-deoxybaccatin III. The Journal of organic chemistry, 2002, Oct-04, Volume: 67, Issue:20 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, Thin Layer; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Paclitaxel; Stereoisomerism; Taxoids	2002
A semiempirical study on the electronic structure of 10-deacetylbaccatin-III. Journal of molecular graphics & modelling, 2002, Volume: 21, Issue:1 Topics: Alkaloids; Drugs, Chinese Herbal; Electrochemistry; Humans; Models, Chemical; Molecular Conformation; Molecular Structure; Paclitaxel; Taxoids	2002
Inhibition of paclitaxel and baccatin III accumulation by mevinolin and fosmidomycin in suspension cultures of Taxus baccata. Journal of biotechnology, 2003, Mar-06, Volume: 101, Issue:2 Topics: Acetates; Alkaloids; Cell Survival; Culture Media; Culture Techniques; Cyclopentanes; Fosfomycin; Lovastatin; Oxylipins; Paclitaxel; Quality Control; Taxoids; Taxus	2003
Analysis of pharmaceutically relevant taxoids in wild yew trees from Sardinia. Fitoterapia, 2003, Volume: 74, Issue:1-2 Topics: Alkaloids; Altitude; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Humans; Italy; Paclitaxel; Phytotherapy; Plant Extracts; Plant Leaves; Soil; Taxoids; Taxus	2003
Dependence of selectivity on eluent composition and temperature in the HPLC separation of taxanes using fluorinated and hydrocarbon phases. Analytical chemistry, 2003, Mar-15, Volume: 75, Issue:6 Topics: Acetonitriles; Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fluorocarbon Polymers; Paclitaxel; Solvents; Taxoids; Temperature	2003
Diastereoselective 14beta-hydroxylation of baccatin III derivatives. The Journal of organic chemistry, 2003, Dec-12, Volume: 68, Issue:25 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Docetaxel; Hydroxylation; Molecular Structure; Oxidation-Reduction; Paclitaxel; Stereoisomerism; Taxoids	2003
Spirobicyclo[2.2.2]octane derivatives: mimetics of baccatin III and paclitaxel (Taxol). Organic & biomolecular chemistry, 2004, Nov-07, Volume: 2, Issue:21 Topics: Alkaloids; Antineoplastic Agents; Biomimetic Materials; Computer Simulation; Models, Molecular; Octanes; Paclitaxel; Spiro Compounds; Taxoids	2004
[Studies on constituents from Taxus mairei Bark]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2004, Volume: 27, Issue:8 Topics: Alkaloids; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Magnetic Resonance Spectroscopy; Molecular Structure; Paclitaxel; Plant Bark; Plants, Medicinal; Taxoids; Taxus	2004
Effects of immobilization by entrapment in alginate and scale-up on paclitaxel and baccatin III production in cell suspension cultures of Taxus baccata. Biotechnology and bioengineering, 2005, Mar-20, Volume: 89, Issue:6 Topics: Alginates; Alkaloids; Antineoplastic Agents, Phytogenic; Biomass; Bioreactors; Biotechnology; Cells, Cultured; Glucuronic Acid; Hexuronic Acids; Paclitaxel; Taxoids; Taxus	2005
Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae. Biotechnology and bioengineering, 2006, Feb-05, Volume: 93, Issue:2 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Coenzyme A-Transferases; Cytochrome P-450 Enzyme System; Farnesyltranstransferase; Genes, Plant; Genetic Engineering; Mixed Function Oxygenases; Paclitaxel; Saccharomyces cerevisiae; Taxoids; Taxus	2006
Matrix-assisted laser desorption/ionization mass spectrometry of taxanes. Rapid communications in mass spectrometry : RCM, 2005, Volume: 19, Issue:23 Topics: Alkaloids; Antineoplastic Agents; Paclitaxel; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Taxoids	2005
[LC-ESI-MS metabolic profiling analysis of taxanes from the extracts of Taxus chinensis cell cultures]. Yao xue xue bao = Acta pharmaceutica Sinica, 2005, Volume: 40, Issue:8 Topics: Alkaloids; Bridged-Ring Compounds; Cells, Cultured; Chromatography, Liquid; Molecular Structure; Molecular Weight; Paclitaxel; Plant Extracts; Plants, Medicinal; Spectrometry, Mass, Electrospray Ionization; Taxoids; Taxus	2005
Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells. Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3 Topics: Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Cattle; Drug Interactions; Endothelial Cells; Female; Microcirculation; Paclitaxel; Permeability; Rhodamines; Taxoids	2006
Profiling a Taxol pathway 10beta-acetyltransferase: assessment of the specificity and the production of baccatin III by in vivo acetylation in E. coli. Chemistry & biology, 2006, Volume: 13, Issue:3 Topics: Acetyl Coenzyme A; Acetylation; Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Catalysis; Chromatography, High Pressure Liquid; Escherichia coli; Models, Chemical; Paclitaxel; Substrate Specificity; Taxoids; Time Factors	2006
Enzymatic C-4 deacetylation of 10-deacetylbaccatin III. Biotechnology and applied biochemistry, 2006, Volume: 45, Issue:Pt 2 Topics: Acetylation; Alkaloids; Aminohydrolases; Antineoplastic Agents, Phytogenic; Bacterial Proteins; Paclitaxel; Rhodococcus; Soil Microbiology; Stenotrophomonas maltophilia; Taxoids	2006
Rapid separation of four main taxoids in Taxus species by a combined LLP-SPE-HPLC (PAD) procedure. Journal of separation science, 2006, Volume: 29, Issue:9 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Humans; Molecular Structure; Paclitaxel; Plants, Medicinal; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Taxoids; Taxus	2006
A formal total synthesis of taxol aided by an automated synthesizer. Chemistry, an Asian journal, 2006, Sep-18, Volume: 1, Issue:3 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Automation; Centrifugation; Chemistry, Pharmaceutical; Computers; Filtration; Microwaves; Models, Chemical; Molecular Structure; Paclitaxel; Stereoisomerism; Taxoids; Technology, Pharmaceutical; Temperature; Time Factors	2006
Microbial transformation of cephalomannine by Luteibacter sp. Journal of natural products, 2007, Volume: 70, Issue:12 Topics: Alkaloids; Antineoplastic Agents; Bacteria; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Paclitaxel; Soil Microbiology; Taxoids; Taxus	2007
Structural characterization of an anhydrous polymorph of paclitaxel by solid-state NMR. Physical chemistry chemical physics : PCCP, 2007, Dec-14, Volume: 9, Issue:46 Topics: Alkaloids; Anhydrides; Antineoplastic Agents; Magnetic Resonance Spectroscopy; Molecular Conformation; Paclitaxel; Taxoids	2007
Vibrational circular dichroism analysis reveals a conformational change of the baccatin III ring of paclitaxel: visualization of conformations using a new code for structure-activity relationships. The Journal of organic chemistry, 2008, Mar-21, Volume: 73, Issue:6 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Circular Dichroism; Models, Molecular; Molecular Conformation; Molecular Structure; Paclitaxel; Structure-Activity Relationship; Taxoids	2008
[Quantitative changes of anti-cancer active components in Taxus chinensis var. mairei branches and leaves]. Ying yong sheng tai xue bao = The journal of applied ecology, 2008, Volume: 19, Issue:4 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Paclitaxel; Plant Leaves; Seasons; Taxoids; Taxus	2008
Taxus globosa S. cell lines: initiation, selection and characterization in terms of growth, and of baccatin III and paclitaxel production. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al, 2010, Volume: 34, Issue:1 Topics: Acetates; Alkaloids; Cell Culture Techniques; Cell Line; Cell Proliferation; Culture Media; Cyclopentanes; Oxylipins; Paclitaxel; Taxoids; Taxus	2010
Baccatin III, a synthetic precursor of taxol, enhances MHC-restricted antigen presentation in dendritic cells. International immunopharmacology, 2011, Volume: 11, Issue:8 Topics: Alkaloids; Animals; Antigen Presentation; Bone Marrow Cells; Cell Line; Dendritic Cells; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Immunologic Factors; Lymphocyte Activation; Major Histocompatibility Complex; Mice; Nanoparticles; Ovalbumin; Paclitaxel; T-Lymphocytes, Cytotoxic; Taxoids	2011
The relationship between TXS, DBAT, BAPT and DBTNBT gene expression and taxane production during the development of Taxus baccata plantlets. Plant science : an international journal of experimental plant biology, 2011, Volume: 181, Issue:3 Topics: Acetyltransferases; Acyltransferases; Alkaloids; Antineoplastic Agents; Bridged-Ring Compounds; Gene Expression; Gene Expression Regulation, Plant; Genes, Plant; Isomerases; Paclitaxel; Plant Components, Aerial; Plant Roots; Taxoids; Taxus	2011
Maintenance of membrane integrity and increase of taxanes production in hazel (Corylus avellana L.) cells induced by low-intensity ultrasound. Biotechnology letters, 2012, Volume: 34, Issue:6 Topics: Alkaloids; Cell Membrane; Cells, Cultured; Corylus; Paclitaxel; Sonication; Taxoids; Time Factors	2012
Isolation of an endophytic fungus producing baccatin III from Taxus wallichiana var. mairei. Journal of industrial microbiology & biotechnology, 2013, Volume: 40, Issue:11 Topics: Alkaloids; Ascomycota; Chromatography, High Pressure Liquid; Culture Media; DNA, Ribosomal; Mass Spectrometry; Paclitaxel; Taxoids; Taxus	2013
Bioproduction of baccatin III, an advanced precursor of paclitaxol, with transgenic Flammulina velutipes expressing the 10-deacetylbaccatin III-10-O-acetyl transferase gene. Journal of the science of food and agriculture, 2014, Volume: 94, Issue:12 Topics: Acetyltransferases; Alkaloids; Flammulina; Genes, Plant; Organisms, Genetically Modified; Paclitaxel; Taxoids; Taxus	2014
Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice. International immunopharmacology, 2014, Volume: 21, Issue:2 Topics: Alkaloids; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Female; Male; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Myeloid Cells; Paclitaxel; Reactive Oxygen Species; T-Lymphocytes; Taxoids	2014
Preparative isolation of paclitaxel and related taxanes from cell cultures of Taxus chinensis using reversed-phase flash chromatography. Natural product research, 2015, Volume: 29, Issue:4 Topics: Alkaloids; Cell Culture Techniques; Chromatography, Reverse-Phase; Paclitaxel; Plant Extracts; Taxoids; Taxus	2015
Development of a hazel cell culture-based paclitaxel and baccatin III production process on a benchtop scale. Journal of biotechnology, 2015, Feb-10, Volume: 195 Topics: Acetates; Alkaloids; Amino Acids; Antineoplastic Agents; Biomass; Bioreactors; Cell Culture Techniques; Cell Proliferation; Cell Survival; Cells, Cultured; Corylus; Cyclopentanes; Indenes; Oxylipins; Paclitaxel; Plant Growth Regulators; Taxoids	2015
Simultaneous determination of seven taxoids in rat plasma by UPLC-MS/MS and pharmacokinetic study after oral administration of Taxus yunnanensis extracts. Journal of pharmaceutical and biomedical analysis, 2015, Mar-25, Volume: 107 Topics: Administration, Oral; Alkaloids; Animals; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Docetaxel; Male; Methyl Ethers; Paclitaxel; Plant Extracts; Plasma; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Taxoids; Taxus	2015
Towards validating new enzymatic routes for synthetic conversion: 7,10-bis-O-(2,2,2-trichloroethoxycarbonyl)-10-deacetyl baccatin III-ethyl acetate-water (1/1/1). Acta crystallographica. Section C, Structural chemistry, 2015, Volume: 71, Issue:Pt 3 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Crystallization; Hydrogen Bonding; Molecular Conformation; Paclitaxel; Taxoids; Water; X-Ray Diffraction	2015
Changes in gene transcription and taxane production in elicited cell cultures of Taxus × media and Taxus globosa. Phytochemistry, 2015, Volume: 117 Topics: Alkaloids; Amino Acids; Bridged-Ring Compounds; Cell Culture Techniques; Cyclodextrins; Indenes; Paclitaxel; Taxoids; Taxus; Transcription, Genetic	2015
Synthesis and anti-inflammatory evaluation of novel paclitaxel analogs. Journal of Asian natural products research, 2017, Volume: 19, Issue:8 Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Combinatorial Chemistry Techniques; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Paclitaxel; Signal Transduction; Taxoids; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha	2017
Paclitaxel Biosynthesis: Adenylation and Thiolation Domains of an NRPS TycA PheAT Module Produce Various Arylisoserine CoA Thioesters. Biochemistry, 2017, 03-14, Volume: 56, Issue:10 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Brevibacillus; Catalytic Domain; Cloning, Molecular; Coenzyme A; Escherichia coli; Gene Expression; Kinetics; Models, Molecular; Paclitaxel; Peptide Synthases; Plant Proteins; Protein Domains; Protein Engineering; Protein Structure, Secondary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Taxoids; Taxus	2017
Isolation of Taxol-Producing Endophytic Fungi from Iranian Yew Through Novel Molecular Approach and Their Effects on Human Breast Cancer Cell Line. Current microbiology, 2017, Volume: 74, Issue:6 Topics: Alkaloids; bcl-2-Associated X Protein; Breast Neoplasms; Cell Line, Tumor; Cladosporium; Endophytes; Female; Humans; Iran; MCF-7 Cells; Paclitaxel; Plant Leaves; Plant Stems; Proto-Oncogene Proteins c-bcl-2; Taxoids; Taxus	2017
Biocatalysis of a Paclitaxel Analogue: Conversion of Baccatin III to N-Debenzoyl-N-(2-furoyl)paclitaxel and Characterization of an Amino Phenylpropanoyl CoA Transferase. Biochemistry, 2017, 11-07, Volume: 56, Issue:44 Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Biocatalysis; Coenzyme A-Transferases; Kinetics; Paclitaxel; Taxoids	2017
Bio-production of Baccatin III, an Important Precursor of Paclitaxel by a Cost-Effective Approach. Molecular biotechnology, 2018, Volume: 60, Issue:7 Topics: Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Bioengineering; Biosynthetic Pathways; Computational Biology; Cost-Benefit Analysis; Genetic Engineering; Models, Molecular; Mutagenesis; Paclitaxel; Substrate Specificity; Taxoids; Taxus; Vinyl Compounds	2018
Activity Essential Residue Analysis of Taxoid 10β-O-Acetyl Transferase for Enzymatic Synthesis of Baccatin. Applied biochemistry and biotechnology, 2018, Volume: 186, Issue:4 Topics: Acetyl Coenzyme A; Aldehyde-Ketone Transferases; Alkaloids; Amino Acid Substitution; Molecular Docking Simulation; Mutation, Missense; Paclitaxel; Plant Proteins; Taxoids; Taxus	2018
[The impurity profiling of paclitaxel and its injection by UPLC-MS/MS]. Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:6 Topics: Alkaloids; China; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Contamination; Injections; Paclitaxel; Tandem Mass Spectrometry; Taxoids	2016
Biochemical insights into the recombinant 10-deacetylbaccatin III-10-β-O-acetyltransferase enzyme from the Taxol-producing endophytic fungus Lasiodiplodia theobromae. FEMS microbiology letters, 2019, 04-01, Volume: 366, Issue:7 Topics: Acetyltransferases; Alkaloids; Ascomycota; Biocatalysis; Cloning, Molecular; Endophytes; Enzyme Stability; Fungal Proteins; Hydrogen-Ion Concentration; Kinetics; Paclitaxel; Recombinant Proteins; Taxoids; Temperature	2019
Optimization of Baccatin III Production by Cross-Linked Enzyme Aggregate of Taxoid 10β-O-Acetyltransferase. Molecular biotechnology, 2019, Volume: 61, Issue:7 Topics: Acetyltransferases; Alkaloids; Cross-Linking Reagents; Enzymes, Immobilized; Paclitaxel; Recombinant Proteins; Taxoids	2019
CoA recycling by a benzoate coenzyme A ligase in cascade reactions with aroyltransferases to biocatalyze paclitaxel analogs. Archives of biochemistry and biophysics, 2020, 04-15, Volume: 683 Topics: Alkaloids; Antineoplastic Agents; Benzoic Acid; Biocatalysis; Bridged-Ring Compounds; Carboxylic Acids; Catalysis; Coenzyme A Ligases; Escherichia coli; Kinetics; Paclitaxel; Rhodopseudomonas; Substrate Specificity; Taxoids	2020
High-effective biosynthesis of baccatin Ⅲ by using the alternative acetyl substrate, N-acetyl-d-glucosamine. Journal of applied microbiology, 2020, Volume: 129, Issue:2 Topics: Acetyl Coenzyme A; Acetylglucosamine; Acetyltransferases; Alkaloids; Antineoplastic Agents, Phytogenic; Biocatalysis; Paclitaxel; Substrate Specificity; Taxoids	2020
Purification and characterization of Taxol and 10-Deacetyl baccatin III from the bark, needles, and endophytes of Taxus baccata by preparative high-performance liquid chromatography, ultra-high-performance liquid chromatography-mass spectrometry, and nucl Journal of separation science, 2023, Volume: 46, Issue:6 Topics: Chromatography, High Pressure Liquid; Endophytes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Needles; Paclitaxel; Plant Bark; Taxoids; Taxus	2023
Structural insight into the stabilization of microtubules by taxanes. eLife, 2023, 03-06, Volume: 12 Topics: Microtubules; Paclitaxel; Taxoids; Tubulin	2023
Synthetic biology identifies the minimal gene set required for paclitaxel biosynthesis in a plant chassis. Molecular plant, 2023, Dec-04, Volume: 16, Issue:12 Topics: Mixed Function Oxygenases; Paclitaxel; Synthetic Biology; Taxoids	2023