Compounds > b 823-08
Page last updated: 2024-09-03

b 823-08 and omeprazole

b 823-08 has been researched along with omeprazole in 8 studies

Compound Research Comparison

Studies
(b 823-08)		Trials
(b 823-08)		Recent Studies (post-2010)
(b 823-08)		Studies
(omeprazole)		Trials
(omeprazole)		Recent Studies (post-2010) (omeprazole)
8109,0852,7371,487

Protein Interaction Comparison

ProteinTaxonomyb 823-08 (IC50)omeprazole (IC50)
Mcl-1Homo sapiens (human)3.1448
cGMP-specific 3',5'-cyclic phosphodiesteraseHomo sapiens (human)0.28
Potassium-transporting ATPase alpha chain 1Homo sapiens (human)1.45
Cytochrome P450 2C19Homo sapiens (human)2.315
Potassium-transporting ATPase subunit betaHomo sapiens (human)1.45
WD repeat-containing protein 5Homo sapiens (human)1.7
Glutathione S-transferase omega-1Homo sapiens (human)4.6
Histone-lysine N-methyltransferase 2AHomo sapiens (human)1.7
Muscarinic acetylcholine receptorCavia porcellus (domestic guinea pig)3.8

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arnold, R; Eissele, R; Koop, H; Krack, W; Lorenz, W; McKnight, AT; Patberg, H1
Adler, G; Arnold, R; Eissele, R; Koop, H; Rosskopf, B1
Arnold, R; Koop, H1
Arnold, R; Eissele, R; Koop, H; Steinbach, F; Tuch, K; Willemer, S1
Bohnenkamp, W; Eltze, M; Heintze, K; Kromer, W; Riedel, R; Schudt, C1
Beil, W; Eltze, M; Heintze, K; Klemm, K; Riedel, R; Schudt, C; Sewing, KF; Simon, A1
Arnold, R; Eissele, R; Koop, H; Koop, I; Meyer, F; Mössner, J; Patberg, H; Richter, S1
Arnold, R; Czornik, M; Eissele, R; Simon, B; Swarovsky, B1

Reviews

1 review(s) available for b 823-08 and omeprazole

ArticleYear
Omeprazole: long-term safety.
    Digestion, 1989, Volume: 44 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Achlorhydria; Animals; Carcinoid Tumor; Clinical Trials as Topic; Drug Administration Schedule; Enterochromaffin Cells; Gastrins; Humans; Omeprazole

1989

Trials

1 trial(s) available for b 823-08 and omeprazole

ArticleYear
Omeprazole: long-term safety.
    Digestion, 1989, Volume: 44 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Achlorhydria; Animals; Carcinoid Tumor; Clinical Trials as Topic; Drug Administration Schedule; Enterochromaffin Cells; Gastrins; Humans; Omeprazole

1989

Other Studies

7 other study(ies) available for b 823-08 and omeprazole

ArticleYear
Effect of gastrin receptor blockade on endocrine cells in rats during achlorhydria.
    Gastroenterology, 1992, Volume: 103, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Achlorhydria; Animals; Enterochromaffin Cells; Gastrins; Histamine; Indoles; Male; Omeprazole; Phenethylamines; Proton Pumps; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Stomach; Time Factors

1992
Proliferation of endocrine cells in the rat stomach caused by drug-induced achlorhydria.
    Gastroenterology, 1991, Volume: 101, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Achlorhydria; Animals; Cell Count; Enterochromaffin Cells; Female; Gastric Mucosa; Gastrins; Hyperplasia; Mitotic Index; Omeprazole; Rats; Rats, Inbred Strains; Regression Analysis; Stomach; Time Factors

1991
Influence of chronic drug-induced achlorhydria by substituted benzimidazoles on the endocrine stomach in rats.
    Gastroenterology, 1987, Volume: 92, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Achlorhydria; Animals; Benzimidazoles; Female; Gastric Acid; Gastric Mucosa; Gastrins; Omeprazole; Rats; Rats, Inbred Strains; Somatostatin; Time Factors

1987
Specificity of the substituted benzimidazole B 823-08: a prodrug for gastric proton pump inhibition.
    Pharmacology, 1987, Volume: 34, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Bile; Depression, Chemical; Dogs; Electrolytes; Electrophysiology; Female; Gastric Acid; Gastric Mucosa; Guinea Pigs; In Vitro Techniques; Kidney; Male; Mice; Muscle, Smooth, Vascular; Omeprazole; Rabbits; Rats; Rats, Inbred Strains; Stomach; Sulfides

1987
The sulphoxide moiety of substituted benzimidazoles is essential for inhibition of parietal cell K+/H+-ATPase.
    British journal of pharmacology, 1986, Volume: 88, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Benzimidazoles; Female; Gastric Acid; Guinea Pigs; H(+)-K(+)-Exchanging ATPase; In Vitro Techniques; Mice; Microsomes, Liver; Omeprazole; Parietal Cells, Gastric; Phosphorylation; Rabbits; Rats; Sulfoxides

1986
A new CCK-B/gastrin receptor antagonist acts as an agonist on the rat pancreas.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1994, Volume: 15, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amino Acid Sequence; Amylases; Analysis of Variance; Animals; Benzodiazepinones; Devazepide; Drug Interactions; Female; In Vitro Techniques; Indoles; Molecular Sequence Data; Omeprazole; Pancreas; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide

1994
Effect of gastrin receptor blockade on gastrin and histidine decarboxylase gene expression in rats during achlorhydria.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Achlorhydria; Animals; Blotting, Northern; Chromogranin A; Chromogranins; Enzyme Inhibitors; Female; Gastrins; Gene Expression; Histidine Decarboxylase; Indoles; Omeprazole; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; RNA, Messenger; Somatostatin

1995