b 669 has been researched along with clofazimine in 16 studies
Studies (b 669) | Trials (b 669) | Recent Studies (post-2010) (b 669) | Studies (clofazimine) | Trials (clofazimine) | Recent Studies (post-2010) (clofazimine) |
---|---|---|---|---|---|
16 | 0 | 0 | 1,377 | 129 | 469 |
Protein | Taxonomy | b 669 (IC50) | clofazimine (IC50) |
---|---|---|---|
ATP-dependent translocase ABCB1 | Homo sapiens (human) | 0.9 | |
Cruzipain | Trypanosoma cruzi | 6 | |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.2 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (12.50) | 18.7374 |
1990's | 14 (87.50) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Conalty, ML; Morrison, NE; O'Sullivan, JF | 1 |
Levy, L | 1 |
Anderson, R; Van Rensburg, CE; Van Staden, AM | 1 |
Dooms, TG; Kuschke, RH; Wadee, AA | 1 |
Anderson, R; Jooné, GK; Myer, MS; O'Sullivan, JF; Van Rensburg, CE | 1 |
van Rensburg, CE; van Straten, A | 1 |
Anderson, R; Smit, MJ | 1 |
Anderson, R; Krajewska, MM | 1 |
Anderson, R; Krajewska, MM; O'Sullivan, JF | 1 |
Myer, MS; Van Rensburg, CE | 1 |
Anderson, R; Dooms, TG; Kuschke, RH; Wadee, AA | 1 |
Anderson, R; Prinsloo, Y; van der Walt, R; van Rensburg, CE | 1 |
Anderson, R; De Bruyn, EE; Steel, HC; Van Rensburg, EJ | 1 |
Anderson, R; Jooné, G; Myer, MS; O'Sullivan, JF; Van Rensburg, CE | 1 |
Anderson, R; Jooné, G; Van Rensburg, CE | 1 |
Anderson, R; Matlola, NM; Steel, HC | 1 |
16 other study(ies) available for b 669 and clofazimine
Article | Year |
---|---|
Clofazimine analogues active against a clofazimine-resistant organism.
Topics: Animals; Cells, Cultured; Clofazimine; Drug Resistance, Microbial; Macrophages; Mice; Mycobacterium; Mycobacterium leprae; Structure-Activity Relationship | 1988 |
Activity of four clofazimine analogues against Mycobacterium leprae.
Topics: Animals; Clofazimine; Mice; Mice, Inbred BALB C; Mycobacterium leprae | 1981 |
The riminophenazine agents clofazimine and B669 inhibit the proliferation of cancer cell lines in vitro by phospholipase A2-mediated oxidative and nonoxidative mechanisms.
Topics: Animals; Arachidonic Acid; Bleomycin; Cell Death; Cell Division; Cisplatin; Clofazimine; Cyclooxygenase Inhibitors; Cytotoxicity, Immunologic; Growth Inhibitors; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Lipoxygenase Inhibitors; Lysophosphatidylcholines; Methotrexate; Neutrophils; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Protein Kinase C; Tumor Cells, Cultured; Vitamin E | 1993 |
The inhibitory effects of Mycobacterium tuberculosis on MHC class II expression by monocytes activated with riminophenazines and phagocyte stimulants.
Topics: Antigens, Bacterial; Antigens, Fungal; Clofazimine; HLA-D Antigens; Humans; Immunosuppressive Agents; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Monocytes; Mycobacterium tuberculosis; Phagocytosis; Saccharomyces cerevisiae | 1995 |
The riminophenazine agents clofazimine and B669 reverse acquired multidrug resistance in a human lung cancer cell line.
Topics: Anti-Infective Agents; Antineoplastic Agents; Carbon Radioisotopes; Carcinoma, Small Cell; Cell Division; Clofazimine; Cyclosporine; Drug Interactions; Drug Resistance, Multiple; Humans; Lung Neoplasms; Tumor Cells, Cultured; Vinblastine | 1994 |
An in-vitro investigation of the susceptibility of Enterococcus faecalis to clofazimine and B669.
Topics: Anti-Bacterial Agents; Clofazimine; Enterococcus faecalis; Microbial Sensitivity Tests | 1994 |
Clofazimine and B669 inhibit the proliferative responses and Na+, K(+)-adenosine triphosphatase activity of human lymphocytes by a lysophospholipid-dependent mechanism.
Topics: Anti-Infective Agents; Arachidonic Acid; Cell Division; Clofazimine; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lysophospholipase; Lysophospholipids; Phospholipases A; Sodium-Potassium-Exchanging ATPase; T-Lymphocytes; Tritium; Vitamin E | 1993 |
An in vitro comparison of the effects of the prooxidative riminophenazines clofazimine and B669 on neutrophil phospholipase A2 activity and superoxide generation.
Topics: Adult; Anti-Infective Agents; Arachidonic Acids; Clofazimine; Humans; In Vitro Techniques; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Superoxides | 1993 |
Effects of clofazimine analogues and tumor necrosis factor-alpha individually and in combination on human polymorphonuclear leukocyte functions in vitro.
Topics: Adult; Cell Degranulation; Clofazimine; Drug Synergism; Humans; In Vitro Techniques; Iodine; Neutrophils; Peroxidase; Superoxides; Tumor Necrosis Factor-alpha | 1993 |
Chemosensitizing interactions of clofazimine and B669 with human K562 erythroleukaemia cells with varying levels of expression of P-glycoprotein.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clofazimine; Drug Interactions; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Ethacrynic Acid; Flow Cytometry; Genistein; Humans; Isoflavones; Leukemia, Erythroblastic, Acute; Tritium; Tumor Cells, Cultured; Vinblastine | 1996 |
The pro-oxidative riminophenazine B669 neutralizes the inhibitory effects of Mycobacterium tuberculosis on phagocyte antimicrobial activity.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Clofazimine; Humans; In Vitro Techniques; Monocytes; Mycobacterium tuberculosis; Neutrophils; Phagocytosis; Respiratory Burst | 1995 |
Augmentative inhibition of lymphocyte proliferation by cyclosporin A combined with the riminophenazine compounds clofazimine and B669.
Topics: Adenosine Triphosphate; Adult; Arachidonic Acid; Clofazimine; Cyclosporine; Drug Synergism; Humans; Immunosuppressive Agents; Lymphocyte Activation; Lysophosphatidylcholines; Sodium-Potassium-Exchanging ATPase | 1995 |
The riminophenazines, clofazimine and B669, inhibit potassium transport in gram-positive bacteria by a lysophospholipid-dependent mechanism.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Biological Transport; Clofazimine; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Lysophosphatidylcholines; Lysophospholipids; Mutation; Potassium; Potassium Radioisotopes; Rubidium Radioisotopes; Vitamin E | 1996 |
Novel tetramethylpiperidine-substituted phenazines are potent inhibitors of P-glycoprotein activity in a multidrug resistant cancer cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clofazimine; Drug Resistance, Multiple; Humans; Leukemia; Molecular Structure; Phenazines; Piperidines; Structure-Activity Relationship; Tumor Cells, Cultured; Vinblastine | 1997 |
Alpha-tocopherol antagonizes the multidrug-resistance-reversal activity of cyclosporin A, verapamil, GF120918, clofazimine and B669.
Topics: Acridines; Cell Death; Clofazimine; Cyclosporine; Drug Resistance, Multiple; Humans; Isoquinolines; Lung Neoplasms; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil; Vinblastine; Vitamin E | 1998 |
Inhibition of potassium transport and growth of mycobacteria exposed to clofazimine and B669 is associated with a calcium-independent increase in microbial phospholipase A2 activity.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Biological Transport; Calcium; Clofazimine; Humans; Mycobacterium; Mycobacterium tuberculosis; Phospholipases A; Phospholipases A2; Potassium | 1999 |