Compounds > aztreonam

aztreonam and serine

aztreonam has been researched along with serine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Bush, K; Dougherty, TJ; Gougoutas, JZ; Malley, MF; Ohringer, S; Singer, SB; Sowek, JA1
Billot-Klein, D; Collatz, E; Gutmann, L; Tran Van Nhieu, G; Williamson, R1
Aklonis, CA; Gillum, AM; O'Sullivan, J; Souser, ML; Sykes, RB1
Frère, JM; Lamotte-Brasseur, J; Matagne, A1
Danizger, LH; Deraedt, MF; Harrington, AT; Wenzler, E1
Dong, D; Feng, K; Gong, H; Jia, N; Liu, Y; Lv, Z; Martins, FS; Sy, S; Sy, SKB; Yu, M; Zhang, J; Zhu, P; Zhu, S; Zhu, Y1
Biagi, M; Deshpande, LM; Lee, M; Mendes, RE; Patel, S; Shajee, A; Wenzler, E; Wu, T1

Other Studies

7 other study(ies) available for aztreonam and serine

ArticleYear
Substitution of lysine at position 104 or 240 of TEM-1pTZ18R beta-lactamase enhances the effect of serine-164 substitution on hydrolysis or affinity for cephalosporins and the monobactam aztreonam.
    Biochemistry, 1991, Apr-02, Volume: 30, Issue:13

    Topics: Aztreonam; beta-Lactamases; Binding Sites; Cephalosporins; Escherichia coli; Hydrolysis; Kinetics; Lysine; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Protein Conformation; Serine; Substrate Specificity

1991
Substitution of serine for arginine in position 162 of TEM-type beta-lactamases extends the substrate profile of mutant enzymes, TEM-7 and TEM-101, to ceftazidime and aztreonam.
    Gene, 1989, May-30, Volume: 78, Issue:2

    Topics: Amino Acid Sequence; Arginine; Aztreonam; beta-Lactamases; Ceftazidime; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Genes, Bacterial; Isoelectric Focusing; Mutation; R Factors; Restriction Mapping; Serine; Substrate Specificity

1989
Biosynthesis of monobactam compounds: origin of the carbon atoms in the beta-lactam ring.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:4

    Topics: Aztreonam; Bacteria; beta-Lactams; Cell-Free System; Chemical Phenomena; Chemistry; Culture Media; Cystine; Serine

1982
Interactions between active-site serine beta-lactamases and so-called beta-lactamase-stable antibiotics. Kinetic and molecular modelling studies.
    European journal of biochemistry, 1993, Oct-01, Volume: 217, Issue:1

    Topics: Actinomycetales; Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Binding Sites; Kinetics; Models, Molecular; Serine; Streptomyces

1993
Synergistic activity of ceftazidime-avibactam and aztreonam against serine and metallo-β-lactamase-producing gram-negative pathogens.
    Diagnostic microbiology and infectious disease, 2017, Volume: 88, Issue:4

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamases; Ceftazidime; Drug Combinations; Drug Synergism; Enterobacteriaceae; Gram-Negative Bacterial Infections; Humans; Pseudomonas aeruginosa; Serine

2017
Aztreonam/avibactam effect on pharmacodynamic indices for mutant selection of Escherichia coli and Klebsiella pneumoniae harbouring serine- and New Delhi metallo-β-lactamases.
    The Journal of antimicrobial chemotherapy, 2021, 10-11, Volume: 76, Issue:11

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamases; Ceftazidime; Drug Combinations; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Serine

2021
Aztreonam in combination with imipenem-relebactam against clinical and isogenic strains of serine and metallo-β-lactamase-producing enterobacterales.
    Diagnostic microbiology and infectious disease, 2022, Volume: 103, Issue:2

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamases; Escherichia coli; Humans; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Serine

2022