Compounds > aztreonam

aztreonam and methicillin

aztreonam has been researched along with methicillin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Kayser, FH; Novak, J; Strässle, A1
Dubus, A; Kania, M; Normark, S; Page, MG1
Bryant, PK; Meroueh, SO; Mobashery, S; Page, MG; Wharton, CW; Wilkinson, AS1

Other Studies

6 other study(ies) available for aztreonam and methicillin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013
Comparative activity of the penem antibiotic Sch 34343 against gram-negative and gram-positive bacteria with special reference to multiresistant strains.
    The Journal of antimicrobial chemotherapy, 1985, Volume: 15 Suppl C

    Topics: Anti-Bacterial Agents; Aztreonam; Cefamandole; Cephalosporins; Corynebacterium; Gram-Negative Bacteria; Gram-Positive Bacteria; Lactams; Methicillin; Microbial Sensitivity Tests; Penicillin Resistance; Staphylococcus

1985
The role of tyrosine 150 in catalysis of beta-lactam hydrolysis by AmpC beta-lactamase from Escherichia coli investigated by site-directed mutagenesis.
    Biochemistry, 1994, Jul-19, Volume: 33, Issue:28

    Topics: Acylation; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Catalysis; Ceftriaxone; Cephalothin; Circular Dichroism; Enzyme Stability; Escherichia coli; Hydrolysis; Kinetics; Methicillin; Mutagenesis, Site-Directed; Plasmids; Protein Structure, Secondary; Restriction Mapping; Structure-Activity Relationship; Tyrosine

1994
A dynamic structure for the acyl-enzyme species of the antibiotic aztreonam with the Citrobacter freundii beta-lactamase revealed by infrared spectroscopy and molecular dynamics simulations.
    Biochemistry, 2003, Feb-25, Volume: 42, Issue:7

    Topics: Acylation; Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Binding Sites; Citrobacter freundii; Computer Simulation; Crystallography, X-Ray; Esters; Hydrogen Bonding; Hydrolysis; Methicillin; Models, Molecular; Protein Conformation; Spectrophotometry, Infrared; Structure-Activity Relationship; Thermodynamics

2003